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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TATDN2-FANCD2 (FusionGDB2 ID:89160)

Fusion Gene Summary for TATDN2-FANCD2

check button Fusion gene summary
Fusion gene informationFusion gene name: TATDN2-FANCD2
Fusion gene ID: 89160
HgeneTgene
Gene symbol

TATDN2

FANCD2

Gene ID

9797

2177

Gene nameTatD DNase domain containing 2FA complementation group D2
Synonyms-FA-D2|FA4|FACD|FAD|FAD2|FANCD
Cytomap

3p25.3

3p25.3

Type of geneprotein-codingprotein-coding
Descriptionputative deoxyribonuclease TATDN2Fanconi anemia group D2 proteinFanconi anemia complementation group D2
Modification date2020031320200313
UniProtAcc.

Q96PS1

Ensembl transtripts involved in fusion geneENST00000287652, ENST00000448281, 
ENST00000496355, 		ENST00000383806, 
ENST00000419585, ENST00000287647, 
ENST00000383807, ENST00000431693, 
ENST00000438741, 
Fusion gene scores* DoF score8 X 7 X 5=2809 X 13 X 7=819
# samples 1011
** MAII scorelog2(10/280*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/819*10)=-2.89635992811635
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TATDN2 [Title/Abstract] AND FANCD2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTATDN2(10291298)-FANCD2(10142872), # samples:2
TATDN2(10291298)-FANCD2(10142871), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneFANCD2

GO:0010332

response to gamma radiation

12874027


check buttonFusion gene breakpoints across TATDN2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FANCD2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-L5-A4OQ-01ATATDN2chr3

10291298

-FANCD2chr3

10142872

+
ChimerDB4ESCATCGA-L5-A4OQ-01ATATDN2chr3

10291298

+FANCD2chr3

10142872

+
ChimerDB4ESCATCGA-L5-A4OQTATDN2chr3

10291298

+FANCD2chr3

10142871

+
ChimerDB4UCECTCGA-FI-A2EX-01ATATDN2chr3

10291298

+FANCD2chr3

10122784

+


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Fusion Gene ORF analysis for TATDN2-FANCD2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000287652ENST00000383806TATDN2chr3

10291298

+FANCD2chr3

10142872

+
5CDS-3UTRENST00000287652ENST00000383806TATDN2chr3

10291298

+FANCD2chr3

10142871

+
5CDS-3UTRENST00000287652ENST00000419585TATDN2chr3

10291298

+FANCD2chr3

10142872

+
5CDS-3UTRENST00000287652ENST00000419585TATDN2chr3

10291298

+FANCD2chr3

10142871

+
5CDS-3UTRENST00000448281ENST00000383806TATDN2chr3

10291298

+FANCD2chr3

10142872

+
5CDS-3UTRENST00000448281ENST00000383806TATDN2chr3

10291298

+FANCD2chr3

10142871

+
5CDS-3UTRENST00000448281ENST00000419585TATDN2chr3

10291298

+FANCD2chr3

10142872

+
5CDS-3UTRENST00000448281ENST00000419585TATDN2chr3

10291298

+FANCD2chr3

10142871

+
5CDS-intronENST00000287652ENST00000287647TATDN2chr3

10291298

+FANCD2chr3

10142872

+
5CDS-intronENST00000287652ENST00000287647TATDN2chr3

10291298

+FANCD2chr3

10142871

+
5CDS-intronENST00000287652ENST00000383807TATDN2chr3

10291298

+FANCD2chr3

10142872

+
5CDS-intronENST00000287652ENST00000383807TATDN2chr3

10291298

+FANCD2chr3

10142871

+
5CDS-intronENST00000287652ENST00000431693TATDN2chr3

10291298

+FANCD2chr3

10142872

+
5CDS-intronENST00000287652ENST00000431693TATDN2chr3

10291298

+FANCD2chr3

10142871

+
5CDS-intronENST00000287652ENST00000431693TATDN2chr3

10291298

+FANCD2chr3

10122784

+
5CDS-intronENST00000287652ENST00000438741TATDN2chr3

10291298

+FANCD2chr3

10142872

+
5CDS-intronENST00000287652ENST00000438741TATDN2chr3

10291298

+FANCD2chr3

10142871

+
5CDS-intronENST00000287652ENST00000438741TATDN2chr3

10291298

+FANCD2chr3

10122784

+
5CDS-intronENST00000448281ENST00000287647TATDN2chr3

10291298

+FANCD2chr3

10142872

+
5CDS-intronENST00000448281ENST00000287647TATDN2chr3

10291298

+FANCD2chr3

10142871

+
5CDS-intronENST00000448281ENST00000383807TATDN2chr3

10291298

+FANCD2chr3

10142872

+
5CDS-intronENST00000448281ENST00000383807TATDN2chr3

10291298

+FANCD2chr3

10142871

+
5CDS-intronENST00000448281ENST00000431693TATDN2chr3

10291298

+FANCD2chr3

10142872

+
5CDS-intronENST00000448281ENST00000431693TATDN2chr3

10291298

+FANCD2chr3

10142871

+
5CDS-intronENST00000448281ENST00000431693TATDN2chr3

10291298

+FANCD2chr3

10122784

+
5CDS-intronENST00000448281ENST00000438741TATDN2chr3

10291298

+FANCD2chr3

10142872

+
5CDS-intronENST00000448281ENST00000438741TATDN2chr3

10291298

+FANCD2chr3

10142871

+
5CDS-intronENST00000448281ENST00000438741TATDN2chr3

10291298

+FANCD2chr3

10122784

+
In-frameENST00000287652ENST00000287647TATDN2chr3

10291298

+FANCD2chr3

10122784

+
In-frameENST00000287652ENST00000383806TATDN2chr3

10291298

+FANCD2chr3

10122784

+
In-frameENST00000287652ENST00000383807TATDN2chr3

10291298

+FANCD2chr3

10122784

+
In-frameENST00000287652ENST00000419585TATDN2chr3

10291298

+FANCD2chr3

10122784

+
In-frameENST00000448281ENST00000287647TATDN2chr3

10291298

+FANCD2chr3

10122784

+
In-frameENST00000448281ENST00000383806TATDN2chr3

10291298

+FANCD2chr3

10122784

+
In-frameENST00000448281ENST00000383807TATDN2chr3

10291298

+FANCD2chr3

10122784

+
In-frameENST00000448281ENST00000419585TATDN2chr3

10291298

+FANCD2chr3

10122784

+
intron-3CDSENST00000496355ENST00000287647TATDN2chr3

10291298

+FANCD2chr3

10122784

+
intron-3CDSENST00000496355ENST00000383806TATDN2chr3

10291298

+FANCD2chr3

10122784

+
intron-3CDSENST00000496355ENST00000383807TATDN2chr3

10291298

+FANCD2chr3

10122784

+
intron-3CDSENST00000496355ENST00000419585TATDN2chr3

10291298

+FANCD2chr3

10122784

+
intron-3UTRENST00000496355ENST00000383806TATDN2chr3

10291298

+FANCD2chr3

10142872

+
intron-3UTRENST00000496355ENST00000383806TATDN2chr3

10291298

+FANCD2chr3

10142871

+
intron-3UTRENST00000496355ENST00000419585TATDN2chr3

10291298

+FANCD2chr3

10142872

+
intron-3UTRENST00000496355ENST00000419585TATDN2chr3

10291298

+FANCD2chr3

10142871

+
intron-intronENST00000496355ENST00000287647TATDN2chr3

10291298

+FANCD2chr3

10142872

+
intron-intronENST00000496355ENST00000287647TATDN2chr3

10291298

+FANCD2chr3

10142871

+
intron-intronENST00000496355ENST00000383807TATDN2chr3

10291298

+FANCD2chr3

10142872

+
intron-intronENST00000496355ENST00000383807TATDN2chr3

10291298

+FANCD2chr3

10142871

+
intron-intronENST00000496355ENST00000431693TATDN2chr3

10291298

+FANCD2chr3

10142872

+
intron-intronENST00000496355ENST00000431693TATDN2chr3

10291298

+FANCD2chr3

10142871

+
intron-intronENST00000496355ENST00000431693TATDN2chr3

10291298

+FANCD2chr3

10122784

+
intron-intronENST00000496355ENST00000438741TATDN2chr3

10291298

+FANCD2chr3

10142872

+
intron-intronENST00000496355ENST00000438741TATDN2chr3

10291298

+FANCD2chr3

10142871

+
intron-intronENST00000496355ENST00000438741TATDN2chr3

10291298

+FANCD2chr3

10122784

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000287652TATDN2chr310291298+ENST00000287647FANCD2chr310122784+3615146510512904617
ENST00000287652TATDN2chr310291298+ENST00000383807FANCD2chr310122784+3513146510512844597
ENST00000287652TATDN2chr310291298+ENST00000383806FANCD2chr310122784+3419146510512238395
ENST00000287652TATDN2chr310291298+ENST00000419585FANCD2chr310122784+3513146510512844597
ENST00000448281TATDN2chr310291298+ENST00000287647FANCD2chr310122784+27265761622015617
ENST00000448281TATDN2chr310291298+ENST00000383807FANCD2chr310122784+26245761621955597
ENST00000448281TATDN2chr310291298+ENST00000383806FANCD2chr310122784+25305761621349395
ENST00000448281TATDN2chr310291298+ENST00000419585FANCD2chr310122784+26245761621955597

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000287652ENST00000287647TATDN2chr310291298+FANCD2chr310122784+0.0157013650.9842986
ENST00000287652ENST00000383807TATDN2chr310291298+FANCD2chr310122784+0.0042710060.995729
ENST00000287652ENST00000383806TATDN2chr310291298+FANCD2chr310122784+0.106479360.89352065
ENST00000287652ENST00000419585TATDN2chr310291298+FANCD2chr310122784+0.0042710060.995729
ENST00000448281ENST00000287647TATDN2chr310291298+FANCD2chr310122784+0.0178005140.98219943
ENST00000448281ENST00000383807TATDN2chr310291298+FANCD2chr310122784+0.0045340010.995466
ENST00000448281ENST00000383806TATDN2chr310291298+FANCD2chr310122784+0.084968550.9150315
ENST00000448281ENST00000419585TATDN2chr310291298+FANCD2chr310122784+0.0045340010.995466

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Fusion Genomic Features for TATDN2-FANCD2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TATDN2chr310291298+FANCD2chr310122783+1.55E-070.9999999
TATDN2chr310291298+FANCD2chr310142871+8.31E-091
TATDN2chr310291298+FANCD2chr310142871+8.31E-091
TATDN2chr310291298+FANCD2chr310122783+1.55E-070.9999999
TATDN2chr310291298+FANCD2chr310142871+8.31E-091
TATDN2chr310291298+FANCD2chr310142871+8.31E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for TATDN2-FANCD2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:10291298/chr3:10142872)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.FANCD2

Q96PS1

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for TATDN2-FANCD2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>89160_89160_1_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000287652_FANCD2_chr3_10122784_ENST00000287647_length(transcript)=3615nt_BP=1465nt
TTTTTTTTTTTTTTTTTGGTGCCTTCTAATTCTAATTCTTCCCATTTCTGGGTGTGTACTTAGTCTCTCTGAGCCACAGTTTTCTGCTCT
ATAAAGTGGGGTGATAATGCTCAGTACACGGTTTGCTTTGGCTCGATGAGAAATCCAGGTCTGAAAGCTTCAGGTACAGCGGCCGGCGCT
GAGGAAAACAGCGTTAAGTGAGGCGCGTCAGCGGACACCACCTGCCTGCACATCTGGCTGGCCTCAACTTCCCGCTGTTCGAGCCCACGT
GAGTGGCTCCGCCCCATCTGGCTTCTGACCAATGGACGAGCTTCCTAAGGCGTACCGTCCCGACTCCAAGGCGCCTGGCTTTGAGGCGGG
CTGCGTCTTGCTCGGAGTCCCGCCCCTTGCCGGGTCGAGCAATGGGCGCCTTCCGTTTGGCGCAGGCCCCGCCCCTGTCGCTCTCCGGCC
TGCGGGCCGCAGGGCTCGTTCCGGAGGGCGGGCGCCACGGAGGCCGGAGTGGTCGCAGTTCGGGCGGAGGCCGGGCCAGGCGGGGCTGTA
GGGCTGGGGCAGGCGGCGGGCTGCCCGGCGGGACAGCTGCGGCAGCCGGCGGGGGGCGTCCTGAGTTGGCGGTCGAGGGCGCTGCCAGCT
CCCGAGGGGCCGCTCGGGCCCCTTCCGGCCCGGGTCTGGTTGGGCCGCAGGAGCAGGGCGGGCTGCGGCGCCCGGGTCTGGCCCTGGCCT
ACGGGCTAAGCGCCCGGCCCCGGGGCCGCGGATCCGGCAGCCATGTGTGGATCTTGAAGCGCCATGTGGTCTTCTGAAGCGCTTGACAGT
TCTAAAGGGCTTTATATTGCAAACTGATCAAAGCGCTTCGTAGCCCCGGAAGCGCTTAGGCATCTCCGAAGTAGCGCTGGGCAAAGTGAA
GGCTTCCTGATCTCAGAAGCACGTTGTGGGCTTGGAAACCGACGGCAGCCTTTAGTCAATTTTGGATCGCTTTGACTTCTCCAACACGGT
TTGGCATCTCTGAAACCTTGAGAACTGTGATGGGCAGTGGAAAGAAGAGGGAAAGGTGCCCATGGCGTCCGAGCGGGGCAAGGTCAAGCA
CAACTGGAGCAGCACGTCGGAAGGGTGTCCCCGCAAGCGCAGCTGCCTCCGGGAGCCCTGTGATGTGGCCCCCTCCAGCCGGCCAGCTCA
GAGGTCTGCGTCGCGTTCTGGAGGGCCCAGCAGCCCCAAGCGCCTGAAAGCCCAGAAGGAGGACGATGTGGCTTGCTCGCGGAGGTTATC
CTGGGGCTCATCCCGCCGCAGAAATAACTCCTCCTCCTCCTTCTCCCCACATTTCTTGGGCCCTGGTGTGGGCGGGGCCGCCTCCAAAGG
CTGCCTGATTCGGAACACTCGGGGGTTCCTGTCTTCAGGGGGATCCCCTCTGCGTCCTGCCAACGCCTCTTTGGAAGAAATGGCTTCTCT
AGAGGAGGAAGCCTGCAGCCTTAAGAACAAAGGAAGCCGGAATATTGGATTCTCACATCTCCAACAGAGATCTGCCCAAGAAATTGTTCA
TTGTGTTTTTCAACTGCTGACCCCAATGTGTAACCACCTGGAGAACATTCACAACTATTTTCAGTGTTTAGCTGCTGAGAATCACGGTGT
AGTTGATGGACCAGGAGTGAAAGTTCAGGAGTACCACATAATGTCTTCCTGCTATCAGAGGCTGCTGCAGATTTTTCATGGGCTTTTTGC
TTGGAGTGGATTTTCTCAACCTGAAAATCAGAATTTACTGTATTCAGCCCTCCATGTCCTTAGTAGCCGACTGAAACAGGGAGAACACAG
CCAGCCTTTGGAGGAACTACTCAGCCAGAGCGTCCATTACTTGCAGAATTTCCATCAAAGCATTCCCAGTTTCCAGTGTGCTCTTTATCT
CATCAGACTTTTGATGGTTATTTTGGAGAAATCAACAGCTTCTGCTCAGAACAAAGAAAAAATTGCTTCCCTTGCCAGACAATTCCTCTG
TCGGGTGTGGCCAAGTGGGGATAAAGAGAAGAGCAACATCTCTAATGACCAGCTCCATGCTCTGCTCTGTATCTACCTGGAGCACACAGA
GAGCATTCTGAAGGCCATAGAGGAGATTGCTGGTGTTGGTGTCCCAGAACTGATCAACTCTCCTAAAGATGCATCTTCCTCCACATTCCC
TACACTGACCAGGCATACTTTTGTTGTTTTCTTCCGTGTGATGATGGCTGAACTAGAGAAGACGGTGAAAAAAATTGAGCCTGGCACAGC
AGCAGACTCGCAGCAGATTCATGAAGAGAAACTCCTCTACTGGAACATGGCTGTTCGAGACTTCAGTATCCTCATCAACTTGATAAAGGT
ATTTGATAGTCATCCTGTTCTGCATGTATGTTTGAAGTATGGGCGTCTCTTTGTGGAAGCATTTCTGAAGCAATGTATGCCGCTCCTAGA
CTTCAGTTTTAGAAAACACCGGGAAGATGTTCTGAGCTTACTGGAAACCTTCCAGTTGGACACAAGGCTGCTTCATCACCTGTGTGGGCA
TTCCAAGATTCACCAGGACACGAGACTCACCCAACATGTGCCTCTGCTCAAAAAGACCCTGGAACTTTTAGTTTGCAGAGTCAAAGCTAT
GCTCACTCTCAACAATTGTAGAGAGGCTTTCTGGCTGGGCAATCTAAAAAACCGGGACTTGCAGGGTGAAGAGATTAAGTCCCAAAATTC
CCAGGAGAGCACAGCAGATGAGAGTGAGGATGACATGTCATCCCAGGCCTCCAAGAGCAAAGCCACTGAGGTATCTCTACAAAACCCACC
AGAGTCTGGCACTGATGGTTGCATTTTGTTAATTGTTCTAAGTTGGTGGAGCAGAACTTTGCCTACTTATGTTTATTGTCAAATGCTTCT
ATGCCCATTTCCATTCCCTCCATAACAGCTTCTGTGCTTATATAATTTTTGGGACCCAGAAGAAACAACGACACAATCTTAGAATCACTC
CTGAGTATCTCGAGTTGTGGCATTTGTTATAGAGTTGACAATTTTCTGCATTATAGCCTCTCATTTTCCATGAATTCATATCTGAAACCA
TTTTAGAAGGGAGAAGTCATCGAAGTATTTTCTGAGTGTTGAGAAGAATGAGTTAAACCATTTAAACACATTTGAAACATACAAAAATAG
AAATGTGAAAGCATTTGGTGAAAGCCAAAGCACAGAGTCAGAAGCTGCCACCTTAGAGAACTGAAATAAAAATAGAAGTTCTTACGCTTT
TTTGTGGTACAGATGCTTTCGACAATTTAAAGAAAGCTAAATAAAAATGTAGACATGGCTGGCGCAGTGGCTCATGCTTGTAATCCTAGC
ACTTTTTGAGGCCAAGGTAGGAGGATTGCTTGAGTCCGGGAGCTCAAGGCAAAGCTGCACAACATAACAAGACCCTATCTCCACAAAAAA
AATGAAAAATAAACCTGGGTGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGATGTGGGCAGATCACAAGGTCAGGAGTTC
AAGACCAGCCTGGCCAACATAGTGAAACCCCATCTCTACTGAAAATACAAAAATTAGCTGGGTGTGGTGGCACGTGCCTGTTATCTCAGC

>89160_89160_1_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000287652_FANCD2_chr3_10122784_ENST00000287647_length(amino acids)=617AA_BP=136
MASERGKVKHNWSSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNSSSSFSPHFLG
PGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEEEACSLKNKGSRNIGFSHLQQRSAQEIVHCVFQLLTPMCNHLENIHNYF
QCLAAENHGVVDGPGVKVQEYHIMSSCYQRLLQIFHGLFAWSGFSQPENQNLLYSALHVLSSRLKQGEHSQPLEELLSQSVHYLQNFHQS
IPSFQCALYLIRLLMVILEKSTASAQNKEKIASLARQFLCRVWPSGDKEKSNISNDQLHALLCIYLEHTESILKAIEEIAGVGVPELINS
PKDASSSTFPTLTRHTFVVFFRVMMAELEKTVKKIEPGTAADSQQIHEEKLLYWNMAVRDFSILINLIKVFDSHPVLHVCLKYGRLFVEA
FLKQCMPLLDFSFRKHREDVLSLLETFQLDTRLLHHLCGHSKIHQDTRLTQHVPLLKKTLELLVCRVKAMLTLNNCREAFWLGNLKNRDL

--------------------------------------------------------------
>89160_89160_2_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000287652_FANCD2_chr3_10122784_ENST00000383806_length(transcript)=3419nt_BP=1465nt
TTTTTTTTTTTTTTTTTGGTGCCTTCTAATTCTAATTCTTCCCATTTCTGGGTGTGTACTTAGTCTCTCTGAGCCACAGTTTTCTGCTCT
ATAAAGTGGGGTGATAATGCTCAGTACACGGTTTGCTTTGGCTCGATGAGAAATCCAGGTCTGAAAGCTTCAGGTACAGCGGCCGGCGCT
GAGGAAAACAGCGTTAAGTGAGGCGCGTCAGCGGACACCACCTGCCTGCACATCTGGCTGGCCTCAACTTCCCGCTGTTCGAGCCCACGT
GAGTGGCTCCGCCCCATCTGGCTTCTGACCAATGGACGAGCTTCCTAAGGCGTACCGTCCCGACTCCAAGGCGCCTGGCTTTGAGGCGGG
CTGCGTCTTGCTCGGAGTCCCGCCCCTTGCCGGGTCGAGCAATGGGCGCCTTCCGTTTGGCGCAGGCCCCGCCCCTGTCGCTCTCCGGCC
TGCGGGCCGCAGGGCTCGTTCCGGAGGGCGGGCGCCACGGAGGCCGGAGTGGTCGCAGTTCGGGCGGAGGCCGGGCCAGGCGGGGCTGTA
GGGCTGGGGCAGGCGGCGGGCTGCCCGGCGGGACAGCTGCGGCAGCCGGCGGGGGGCGTCCTGAGTTGGCGGTCGAGGGCGCTGCCAGCT
CCCGAGGGGCCGCTCGGGCCCCTTCCGGCCCGGGTCTGGTTGGGCCGCAGGAGCAGGGCGGGCTGCGGCGCCCGGGTCTGGCCCTGGCCT
ACGGGCTAAGCGCCCGGCCCCGGGGCCGCGGATCCGGCAGCCATGTGTGGATCTTGAAGCGCCATGTGGTCTTCTGAAGCGCTTGACAGT
TCTAAAGGGCTTTATATTGCAAACTGATCAAAGCGCTTCGTAGCCCCGGAAGCGCTTAGGCATCTCCGAAGTAGCGCTGGGCAAAGTGAA
GGCTTCCTGATCTCAGAAGCACGTTGTGGGCTTGGAAACCGACGGCAGCCTTTAGTCAATTTTGGATCGCTTTGACTTCTCCAACACGGT
TTGGCATCTCTGAAACCTTGAGAACTGTGATGGGCAGTGGAAAGAAGAGGGAAAGGTGCCCATGGCGTCCGAGCGGGGCAAGGTCAAGCA
CAACTGGAGCAGCACGTCGGAAGGGTGTCCCCGCAAGCGCAGCTGCCTCCGGGAGCCCTGTGATGTGGCCCCCTCCAGCCGGCCAGCTCA
GAGGTCTGCGTCGCGTTCTGGAGGGCCCAGCAGCCCCAAGCGCCTGAAAGCCCAGAAGGAGGACGATGTGGCTTGCTCGCGGAGGTTATC
CTGGGGCTCATCCCGCCGCAGAAATAACTCCTCCTCCTCCTTCTCCCCACATTTCTTGGGCCCTGGTGTGGGCGGGGCCGCCTCCAAAGG
CTGCCTGATTCGGAACACTCGGGGGTTCCTGTCTTCAGGGGGATCCCCTCTGCGTCCTGCCAACGCCTCTTTGGAAGAAATGGCTTCTCT
AGAGGAGGAAGCCTGCAGCCTTAAGAACAAAGGAAGCCGGAATATTGGATTCTCACATCTCCAACAGAGATCTGCCCAAGAAATTGTTCA
TTGTGTTTTTCAACTGCTGACCCCAATGTGTAACCACCTGGAGAACATTCACAACTATTTTCAGTGTTTAGCTGCTGAGAATCACGGTGT
AGTTGATGGACCAGGAGTGAAAGTTCAGGAGTACCACATAATGTCTTCCTGCTATCAGAGGCTGCTGCAGATTTTTCATGGGCTTTTTGC
TTGGAGTGGATTTTCTCAACCTGAAAATCAGAATTTACTGTATTCAGCCCTCCATGTCCTTAGTAGCCGACTGAAACAGGGAGAACACAG
CCAGCCTTTGGAGGAACTACTCAGCCAGAGCGTCCATTACTTGCAGAATTTCCATCAAAGCATTCCCAGTTTCCAGTGTGCTCTTTATCT
CATCAGACTTTTGATGGTTATTTTGGAGAAATCAACAGCTTCTGCTCAGAACAAAGAAAAAATTGCTTCCCTTGCCAGACAATTCCTCTG
TCGGGTGTGGCCAAGTGGGGATAAAGAGAAGAGCAACATCTCTAATGACCAGCTCCATGCTCTGCTCTGTATCTACCTGGAGCACACAGA
GAGCATTCTGAAGGCCATAGAGGAGATTGCTGGTGTTGGTGTCCCAGAACTGATCAACTCTCCTAAAGATGCATCTTCCTCCACATTCCC
TACACTGACCAGATTCATGAAGAGAAACTCCTCTACTGGAACATGGCTGTTCGAGACTTCAGTATCCTCATCAACTTGATAAAGGTATTT
GATAGTCATCCTGTTCTGCATGTATGTTTGAAGTATGGGCGTCTCTTTGTGGAAGCATTTCTGAAGCAATGTATGCCGCTCCTAGACTTC
AGTTTTAGAAAACACCGGGAAGATGTTCTGAGCTTACTGGAAACCTTCCAGTTGGACACAAGGCTGCTTCATCACCTGTGTGGGCATTCC
AAGATTCACCAGGACACGAGACTCACCCAACATGTGCCTCTGCTCAAAAAGACCCTGGAACTTTTAGTTTGCAGAGTCAAAGCTATGCTC
ACTCTCAACAATTGTAGAGAGGCTTTCTGGCTGGGCAATCTAAAAAACCGGGACTTGCAGGGTGAAGAGATTAAGTCCCAAAATTCCCAG
GAGAGCACAGCAGATGAGAGTGAGGATGACATGTCATCCCAGGCCTCCAAGAGCAAAGCCACTGAGGATGGTGAAGAAGACGAAGTAAGT
GCTGGAGAAAAGGAGCAAGATAGTGATGAGAGTTATGATGACTCTGATTAGACCCCAGATAAATTGTTGCCTGCTTCTGTGTCTCTGCCA
GCCTGTGATCATTTTGTGTTAGAGTTTGAAATCCGCTGTTTGCCTTTCTTACTGGTAGGATCCTTTTTTGTTCCTCTTTTTTTTTTTTTT
TTTTTTTTTTTAAAGACGGGGACTCGCTGTGTTTCCCAGGCTGGAGTGCAGTGCTGCAATCTTGGCTCACTGCAACCTCCATCTCCTAGG
TTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACGACAGGCACATGCCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGA
TACGGGGTTTTACCATGTCGGCCAGATGGTCTCAATCTCCTGAACTCATGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGG
CATGAGCCACCGCTCCCAGCCATATTTTGTTCTTAAAGTGGGGTCTTTATTAACTTGTGGACATCATGGATTGTCTAACACCATCACAGT
CCCTGGCTCAGGATTCTAATGTAGCATTATTTATTGGTTTGGATAAACCCAGCTGTGCTACACTGCAGAGTAAAATCTCTGAGTCATGAT

>89160_89160_2_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000287652_FANCD2_chr3_10122784_ENST00000383806_length(amino acids)=395AA_BP=136
MASERGKVKHNWSSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNSSSSFSPHFLG
PGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEEEACSLKNKGSRNIGFSHLQQRSAQEIVHCVFQLLTPMCNHLENIHNYF
QCLAAENHGVVDGPGVKVQEYHIMSSCYQRLLQIFHGLFAWSGFSQPENQNLLYSALHVLSSRLKQGEHSQPLEELLSQSVHYLQNFHQS
IPSFQCALYLIRLLMVILEKSTASAQNKEKIASLARQFLCRVWPSGDKEKSNISNDQLHALLCIYLEHTESILKAIEEIAGVGVPELINS

--------------------------------------------------------------
>89160_89160_3_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000287652_FANCD2_chr3_10122784_ENST00000383807_length(transcript)=3513nt_BP=1465nt
TTTTTTTTTTTTTTTTTGGTGCCTTCTAATTCTAATTCTTCCCATTTCTGGGTGTGTACTTAGTCTCTCTGAGCCACAGTTTTCTGCTCT
ATAAAGTGGGGTGATAATGCTCAGTACACGGTTTGCTTTGGCTCGATGAGAAATCCAGGTCTGAAAGCTTCAGGTACAGCGGCCGGCGCT
GAGGAAAACAGCGTTAAGTGAGGCGCGTCAGCGGACACCACCTGCCTGCACATCTGGCTGGCCTCAACTTCCCGCTGTTCGAGCCCACGT
GAGTGGCTCCGCCCCATCTGGCTTCTGACCAATGGACGAGCTTCCTAAGGCGTACCGTCCCGACTCCAAGGCGCCTGGCTTTGAGGCGGG
CTGCGTCTTGCTCGGAGTCCCGCCCCTTGCCGGGTCGAGCAATGGGCGCCTTCCGTTTGGCGCAGGCCCCGCCCCTGTCGCTCTCCGGCC
TGCGGGCCGCAGGGCTCGTTCCGGAGGGCGGGCGCCACGGAGGCCGGAGTGGTCGCAGTTCGGGCGGAGGCCGGGCCAGGCGGGGCTGTA
GGGCTGGGGCAGGCGGCGGGCTGCCCGGCGGGACAGCTGCGGCAGCCGGCGGGGGGCGTCCTGAGTTGGCGGTCGAGGGCGCTGCCAGCT
CCCGAGGGGCCGCTCGGGCCCCTTCCGGCCCGGGTCTGGTTGGGCCGCAGGAGCAGGGCGGGCTGCGGCGCCCGGGTCTGGCCCTGGCCT
ACGGGCTAAGCGCCCGGCCCCGGGGCCGCGGATCCGGCAGCCATGTGTGGATCTTGAAGCGCCATGTGGTCTTCTGAAGCGCTTGACAGT
TCTAAAGGGCTTTATATTGCAAACTGATCAAAGCGCTTCGTAGCCCCGGAAGCGCTTAGGCATCTCCGAAGTAGCGCTGGGCAAAGTGAA
GGCTTCCTGATCTCAGAAGCACGTTGTGGGCTTGGAAACCGACGGCAGCCTTTAGTCAATTTTGGATCGCTTTGACTTCTCCAACACGGT
TTGGCATCTCTGAAACCTTGAGAACTGTGATGGGCAGTGGAAAGAAGAGGGAAAGGTGCCCATGGCGTCCGAGCGGGGCAAGGTCAAGCA
CAACTGGAGCAGCACGTCGGAAGGGTGTCCCCGCAAGCGCAGCTGCCTCCGGGAGCCCTGTGATGTGGCCCCCTCCAGCCGGCCAGCTCA
GAGGTCTGCGTCGCGTTCTGGAGGGCCCAGCAGCCCCAAGCGCCTGAAAGCCCAGAAGGAGGACGATGTGGCTTGCTCGCGGAGGTTATC
CTGGGGCTCATCCCGCCGCAGAAATAACTCCTCCTCCTCCTTCTCCCCACATTTCTTGGGCCCTGGTGTGGGCGGGGCCGCCTCCAAAGG
CTGCCTGATTCGGAACACTCGGGGGTTCCTGTCTTCAGGGGGATCCCCTCTGCGTCCTGCCAACGCCTCTTTGGAAGAAATGGCTTCTCT
AGAGGAGGAAGCCTGCAGCCTTAAGAACAAAGGAAGCCGGAATATTGGATTCTCACATCTCCAACAGAGATCTGCCCAAGAAATTGTTCA
TTGTGTTTTTCAACTGCTGACCCCAATGTGTAACCACCTGGAGAACATTCACAACTATTTTCAGTGTTTAGCTGCTGAGAATCACGGTGT
AGTTGATGGACCAGGAGTGAAAGTTCAGGAGTACCACATAATGTCTTCCTGCTATCAGAGGCTGCTGCAGATTTTTCATGGGCTTTTTGC
TTGGAGTGGATTTTCTCAACCTGAAAATCAGAATTTACTGTATTCAGCCCTCCATGTCCTTAGTAGCCGACTGAAACAGGGAGAACACAG
CCAGCCTTTGGAGGAACTACTCAGCCAGAGCGTCCATTACTTGCAGAATTTCCATCAAAGCATTCCCAGTTTCCAGTGTGCTCTTTATCT
CATCAGACTTTTGATGGTTATTTTGGAGAAATCAACAGCTTCTGCTCAGAACAAAGAAAAAATTGCTTCCCTTGCCAGACAATTCCTCTG
TCGGGTGTGGCCAAGTGGGGATAAAGAGAAGAGCAACATCTCTAATGACCAGCTCCATGCTCTGCTCTGTATCTACCTGGAGCACACAGA
GAGCATTCTGAAGGCCATAGAGGAGATTGCTGGTGTTGGTGTCCCAGAACTGATCAACTCTCCTAAAGATGCATCTTCCTCCACATTCCC
TACACTGACCAGGCATACTTTTGTTGTTTTCTTCCGTGTGATGATGGCTGAACTAGAGAAGACGGTGAAAAAAATTGAGCCTGGCACAGC
AGCAGACTCGCAGCAGATTCATGAAGAGAAACTCCTCTACTGGAACATGGCTGTTCGAGACTTCAGTATCCTCATCAACTTGATAAAGGT
ATTTGATAGTCATCCTGTTCTGCATGTATGTTTGAAGTATGGGCGTCTCTTTGTGGAAGCATTTCTGAAGCAATGTATGCCGCTCCTAGA
CTTCAGTTTTAGAAAACACCGGGAAGATGTTCTGAGCTTACTGGAAACCTTCCAGTTGGACACAAGGCTGCTTCATCACCTGTGTGGGCA
TTCCAAGATTCACCAGGACACGAGACTCACCCAACATGTGCCTCTGCTCAAAAAGACCCTGGAACTTTTAGTTTGCAGAGTCAAAGCTAT
GCTCACTCTCAACAATTGTAGAGAGGCTTTCTGGCTGGGCAATCTAAAAAACCGGGACTTGCAGGGTGAAGAGATTAAGTCCCAAAATTC
CCAGGAGAGCACAGCAGATGAGAGTGAGGATGACATGTCATCCCAGGCCTCCAAGAGCAAAGCCACTGAGGATGGTGAAGAAGACGAAGT
AAGTGCTGGAGAAAAGGAGCAAGATAGTGATGAGAGTTATGATGACTCTGATTAGACCCCAGATAAATTGTTGCCTGCTTCTGTGTCTCT
GCCAGCCTGTGATCATTTTGTGTTAGAGTTTGAAATCCGCTGTTTGCCTTTCTTACTGGTAGGATCCTTTTTTGTTCCTCTTTTTTTTTT
TTTTTTTTTTTTTTTAAAGACGGGGACTCGCTGTGTTTCCCAGGCTGGAGTGCAGTGCTGCAATCTTGGCTCACTGCAACCTCCATCTCC
TAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACGACAGGCACATGCCACCATGCCCAGCTAATTTTTGTATTTTTAG
TAGATACGGGGTTTTACCATGTCGGCCAGATGGTCTCAATCTCCTGAACTCATGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTA
CAGGCATGAGCCACCGCTCCCAGCCATATTTTGTTCTTAAAGTGGGGTCTTTATTAACTTGTGGACATCATGGATTGTCTAACACCATCA
CAGTCCCTGGCTCAGGATTCTAATGTAGCATTATTTATTGGTTTGGATAAACCCAGCTGTGCTACACTGCAGAGTAAAATCTCTGAGTCA
TGATTCTGGACTTTGGGAGCTAGTTTTGAAACTCTGATTTATTGTAGAACTTAGGCTTGTACCAATTTTACAAATAAATTCTGTTCTAAG

>89160_89160_3_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000287652_FANCD2_chr3_10122784_ENST00000383807_length(amino acids)=597AA_BP=136
MASERGKVKHNWSSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNSSSSFSPHFLG
PGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEEEACSLKNKGSRNIGFSHLQQRSAQEIVHCVFQLLTPMCNHLENIHNYF
QCLAAENHGVVDGPGVKVQEYHIMSSCYQRLLQIFHGLFAWSGFSQPENQNLLYSALHVLSSRLKQGEHSQPLEELLSQSVHYLQNFHQS
IPSFQCALYLIRLLMVILEKSTASAQNKEKIASLARQFLCRVWPSGDKEKSNISNDQLHALLCIYLEHTESILKAIEEIAGVGVPELINS
PKDASSSTFPTLTRHTFVVFFRVMMAELEKTVKKIEPGTAADSQQIHEEKLLYWNMAVRDFSILINLIKVFDSHPVLHVCLKYGRLFVEA
FLKQCMPLLDFSFRKHREDVLSLLETFQLDTRLLHHLCGHSKIHQDTRLTQHVPLLKKTLELLVCRVKAMLTLNNCREAFWLGNLKNRDL

--------------------------------------------------------------
>89160_89160_4_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000287652_FANCD2_chr3_10122784_ENST00000419585_length(transcript)=3513nt_BP=1465nt
TTTTTTTTTTTTTTTTTGGTGCCTTCTAATTCTAATTCTTCCCATTTCTGGGTGTGTACTTAGTCTCTCTGAGCCACAGTTTTCTGCTCT
ATAAAGTGGGGTGATAATGCTCAGTACACGGTTTGCTTTGGCTCGATGAGAAATCCAGGTCTGAAAGCTTCAGGTACAGCGGCCGGCGCT
GAGGAAAACAGCGTTAAGTGAGGCGCGTCAGCGGACACCACCTGCCTGCACATCTGGCTGGCCTCAACTTCCCGCTGTTCGAGCCCACGT
GAGTGGCTCCGCCCCATCTGGCTTCTGACCAATGGACGAGCTTCCTAAGGCGTACCGTCCCGACTCCAAGGCGCCTGGCTTTGAGGCGGG
CTGCGTCTTGCTCGGAGTCCCGCCCCTTGCCGGGTCGAGCAATGGGCGCCTTCCGTTTGGCGCAGGCCCCGCCCCTGTCGCTCTCCGGCC
TGCGGGCCGCAGGGCTCGTTCCGGAGGGCGGGCGCCACGGAGGCCGGAGTGGTCGCAGTTCGGGCGGAGGCCGGGCCAGGCGGGGCTGTA
GGGCTGGGGCAGGCGGCGGGCTGCCCGGCGGGACAGCTGCGGCAGCCGGCGGGGGGCGTCCTGAGTTGGCGGTCGAGGGCGCTGCCAGCT
CCCGAGGGGCCGCTCGGGCCCCTTCCGGCCCGGGTCTGGTTGGGCCGCAGGAGCAGGGCGGGCTGCGGCGCCCGGGTCTGGCCCTGGCCT
ACGGGCTAAGCGCCCGGCCCCGGGGCCGCGGATCCGGCAGCCATGTGTGGATCTTGAAGCGCCATGTGGTCTTCTGAAGCGCTTGACAGT
TCTAAAGGGCTTTATATTGCAAACTGATCAAAGCGCTTCGTAGCCCCGGAAGCGCTTAGGCATCTCCGAAGTAGCGCTGGGCAAAGTGAA
GGCTTCCTGATCTCAGAAGCACGTTGTGGGCTTGGAAACCGACGGCAGCCTTTAGTCAATTTTGGATCGCTTTGACTTCTCCAACACGGT
TTGGCATCTCTGAAACCTTGAGAACTGTGATGGGCAGTGGAAAGAAGAGGGAAAGGTGCCCATGGCGTCCGAGCGGGGCAAGGTCAAGCA
CAACTGGAGCAGCACGTCGGAAGGGTGTCCCCGCAAGCGCAGCTGCCTCCGGGAGCCCTGTGATGTGGCCCCCTCCAGCCGGCCAGCTCA
GAGGTCTGCGTCGCGTTCTGGAGGGCCCAGCAGCCCCAAGCGCCTGAAAGCCCAGAAGGAGGACGATGTGGCTTGCTCGCGGAGGTTATC
CTGGGGCTCATCCCGCCGCAGAAATAACTCCTCCTCCTCCTTCTCCCCACATTTCTTGGGCCCTGGTGTGGGCGGGGCCGCCTCCAAAGG
CTGCCTGATTCGGAACACTCGGGGGTTCCTGTCTTCAGGGGGATCCCCTCTGCGTCCTGCCAACGCCTCTTTGGAAGAAATGGCTTCTCT
AGAGGAGGAAGCCTGCAGCCTTAAGAACAAAGGAAGCCGGAATATTGGATTCTCACATCTCCAACAGAGATCTGCCCAAGAAATTGTTCA
TTGTGTTTTTCAACTGCTGACCCCAATGTGTAACCACCTGGAGAACATTCACAACTATTTTCAGTGTTTAGCTGCTGAGAATCACGGTGT
AGTTGATGGACCAGGAGTGAAAGTTCAGGAGTACCACATAATGTCTTCCTGCTATCAGAGGCTGCTGCAGATTTTTCATGGGCTTTTTGC
TTGGAGTGGATTTTCTCAACCTGAAAATCAGAATTTACTGTATTCAGCCCTCCATGTCCTTAGTAGCCGACTGAAACAGGGAGAACACAG
CCAGCCTTTGGAGGAACTACTCAGCCAGAGCGTCCATTACTTGCAGAATTTCCATCAAAGCATTCCCAGTTTCCAGTGTGCTCTTTATCT
CATCAGACTTTTGATGGTTATTTTGGAGAAATCAACAGCTTCTGCTCAGAACAAAGAAAAAATTGCTTCCCTTGCCAGACAATTCCTCTG
TCGGGTGTGGCCAAGTGGGGATAAAGAGAAGAGCAACATCTCTAATGACCAGCTCCATGCTCTGCTCTGTATCTACCTGGAGCACACAGA
GAGCATTCTGAAGGCCATAGAGGAGATTGCTGGTGTTGGTGTCCCAGAACTGATCAACTCTCCTAAAGATGCATCTTCCTCCACATTCCC
TACACTGACCAGGCATACTTTTGTTGTTTTCTTCCGTGTGATGATGGCTGAACTAGAGAAGACGGTGAAAAAAATTGAGCCTGGCACAGC
AGCAGACTCGCAGCAGATTCATGAAGAGAAACTCCTCTACTGGAACATGGCTGTTCGAGACTTCAGTATCCTCATCAACTTGATAAAGGT
ATTTGATAGTCATCCTGTTCTGCATGTATGTTTGAAGTATGGGCGTCTCTTTGTGGAAGCATTTCTGAAGCAATGTATGCCGCTCCTAGA
CTTCAGTTTTAGAAAACACCGGGAAGATGTTCTGAGCTTACTGGAAACCTTCCAGTTGGACACAAGGCTGCTTCATCACCTGTGTGGGCA
TTCCAAGATTCACCAGGACACGAGACTCACCCAACATGTGCCTCTGCTCAAAAAGACCCTGGAACTTTTAGTTTGCAGAGTCAAAGCTAT
GCTCACTCTCAACAATTGTAGAGAGGCTTTCTGGCTGGGCAATCTAAAAAACCGGGACTTGCAGGGTGAAGAGATTAAGTCCCAAAATTC
CCAGGAGAGCACAGCAGATGAGAGTGAGGATGACATGTCATCCCAGGCCTCCAAGAGCAAAGCCACTGAGGATGGTGAAGAAGACGAAGT
AAGTGCTGGAGAAAAGGAGCAAGATAGTGATGAGAGTTATGATGACTCTGATTAGACCCCAGATAAATTGTTGCCTGCTTCTGTGTCTCT
GCCAGCCTGTGATCATTTTGTGTTAGAGTTTGAAATCCGCTGTTTGCCTTTCTTACTGGTAGGATCCTTTTTTGTTCCTCTTTTTTTTTT
TTTTTTTTTTTTTTTAAAGACGGGGACTCGCTGTGTTTCCCAGGCTGGAGTGCAGTGCTGCAATCTTGGCTCACTGCAACCTCCATCTCC
TAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACGACAGGCACATGCCACCATGCCCAGCTAATTTTTGTATTTTTAG
TAGATACGGGGTTTTACCATGTCGGCCAGATGGTCTCAATCTCCTGAACTCATGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTA
CAGGCATGAGCCACCGCTCCCAGCCATATTTTGTTCTTAAAGTGGGGTCTTTATTAACTTGTGGACATCATGGATTGTCTAACACCATCA
CAGTCCCTGGCTCAGGATTCTAATGTAGCATTATTTATTGGTTTGGATAAACCCAGCTGTGCTACACTGCAGAGTAAAATCTCTGAGTCA
TGATTCTGGACTTTGGGAGCTAGTTTTGAAACTCTGATTTATTGTAGAACTTAGGCTTGTACCAATTTTACAAATAAATTCTGTTCTAAG

>89160_89160_4_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000287652_FANCD2_chr3_10122784_ENST00000419585_length(amino acids)=597AA_BP=136
MASERGKVKHNWSSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNSSSSFSPHFLG
PGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEEEACSLKNKGSRNIGFSHLQQRSAQEIVHCVFQLLTPMCNHLENIHNYF
QCLAAENHGVVDGPGVKVQEYHIMSSCYQRLLQIFHGLFAWSGFSQPENQNLLYSALHVLSSRLKQGEHSQPLEELLSQSVHYLQNFHQS
IPSFQCALYLIRLLMVILEKSTASAQNKEKIASLARQFLCRVWPSGDKEKSNISNDQLHALLCIYLEHTESILKAIEEIAGVGVPELINS
PKDASSSTFPTLTRHTFVVFFRVMMAELEKTVKKIEPGTAADSQQIHEEKLLYWNMAVRDFSILINLIKVFDSHPVLHVCLKYGRLFVEA
FLKQCMPLLDFSFRKHREDVLSLLETFQLDTRLLHHLCGHSKIHQDTRLTQHVPLLKKTLELLVCRVKAMLTLNNCREAFWLGNLKNRDL

--------------------------------------------------------------
>89160_89160_5_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000448281_FANCD2_chr3_10122784_ENST00000287647_length(transcript)=2726nt_BP=576nt
GGCAAAGTGAAGGCTTCCTGATCTCAGAAGCACGTTGTGGGCTTGGAAACCGACGGCAGCCTTTAGTCAATTTTGGATCGCTTTGACTTC
TCCAACACGGTTTGGCATCTCTGAAACCTTGAGAACTGTGATGGGCAGTGGAAAGAAGAGGGAAAGGTGCCCATGGCGTCCGAGCGGGGC
AAGGTCAAGCACAACTGGAGCAGCACGTCGGAAGGGTGTCCCCGCAAGCGCAGCTGCCTCCGGGAGCCCTGTGATGTGGCCCCCTCCAGC
CGGCCAGCTCAGAGGTCTGCGTCGCGTTCTGGAGGGCCCAGCAGCCCCAAGCGCCTGAAAGCCCAGAAGGAGGACGATGTGGCTTGCTCG
CGGAGGTTATCCTGGGGCTCATCCCGCCGCAGAAATAACTCCTCCTCCTCCTTCTCCCCACATTTCTTGGGCCCTGGTGTGGGCGGGGCC
GCCTCCAAAGGCTGCCTGATTCGGAACACTCGGGGGTTCCTGTCTTCAGGGGGATCCCCTCTGCGTCCTGCCAACGCCTCTTTGGAAGAA
ATGGCTTCTCTAGAGGAGGAAGCCTGCAGCCTTAAGAACAAAGGAAGCCGGAATATTGGATTCTCACATCTCCAACAGAGATCTGCCCAA
GAAATTGTTCATTGTGTTTTTCAACTGCTGACCCCAATGTGTAACCACCTGGAGAACATTCACAACTATTTTCAGTGTTTAGCTGCTGAG
AATCACGGTGTAGTTGATGGACCAGGAGTGAAAGTTCAGGAGTACCACATAATGTCTTCCTGCTATCAGAGGCTGCTGCAGATTTTTCAT
GGGCTTTTTGCTTGGAGTGGATTTTCTCAACCTGAAAATCAGAATTTACTGTATTCAGCCCTCCATGTCCTTAGTAGCCGACTGAAACAG
GGAGAACACAGCCAGCCTTTGGAGGAACTACTCAGCCAGAGCGTCCATTACTTGCAGAATTTCCATCAAAGCATTCCCAGTTTCCAGTGT
GCTCTTTATCTCATCAGACTTTTGATGGTTATTTTGGAGAAATCAACAGCTTCTGCTCAGAACAAAGAAAAAATTGCTTCCCTTGCCAGA
CAATTCCTCTGTCGGGTGTGGCCAAGTGGGGATAAAGAGAAGAGCAACATCTCTAATGACCAGCTCCATGCTCTGCTCTGTATCTACCTG
GAGCACACAGAGAGCATTCTGAAGGCCATAGAGGAGATTGCTGGTGTTGGTGTCCCAGAACTGATCAACTCTCCTAAAGATGCATCTTCC
TCCACATTCCCTACACTGACCAGGCATACTTTTGTTGTTTTCTTCCGTGTGATGATGGCTGAACTAGAGAAGACGGTGAAAAAAATTGAG
CCTGGCACAGCAGCAGACTCGCAGCAGATTCATGAAGAGAAACTCCTCTACTGGAACATGGCTGTTCGAGACTTCAGTATCCTCATCAAC
TTGATAAAGGTATTTGATAGTCATCCTGTTCTGCATGTATGTTTGAAGTATGGGCGTCTCTTTGTGGAAGCATTTCTGAAGCAATGTATG
CCGCTCCTAGACTTCAGTTTTAGAAAACACCGGGAAGATGTTCTGAGCTTACTGGAAACCTTCCAGTTGGACACAAGGCTGCTTCATCAC
CTGTGTGGGCATTCCAAGATTCACCAGGACACGAGACTCACCCAACATGTGCCTCTGCTCAAAAAGACCCTGGAACTTTTAGTTTGCAGA
GTCAAAGCTATGCTCACTCTCAACAATTGTAGAGAGGCTTTCTGGCTGGGCAATCTAAAAAACCGGGACTTGCAGGGTGAAGAGATTAAG
TCCCAAAATTCCCAGGAGAGCACAGCAGATGAGAGTGAGGATGACATGTCATCCCAGGCCTCCAAGAGCAAAGCCACTGAGGTATCTCTA
CAAAACCCACCAGAGTCTGGCACTGATGGTTGCATTTTGTTAATTGTTCTAAGTTGGTGGAGCAGAACTTTGCCTACTTATGTTTATTGT
CAAATGCTTCTATGCCCATTTCCATTCCCTCCATAACAGCTTCTGTGCTTATATAATTTTTGGGACCCAGAAGAAACAACGACACAATCT
TAGAATCACTCCTGAGTATCTCGAGTTGTGGCATTTGTTATAGAGTTGACAATTTTCTGCATTATAGCCTCTCATTTTCCATGAATTCAT
ATCTGAAACCATTTTAGAAGGGAGAAGTCATCGAAGTATTTTCTGAGTGTTGAGAAGAATGAGTTAAACCATTTAAACACATTTGAAACA
TACAAAAATAGAAATGTGAAAGCATTTGGTGAAAGCCAAAGCACAGAGTCAGAAGCTGCCACCTTAGAGAACTGAAATAAAAATAGAAGT
TCTTACGCTTTTTTGTGGTACAGATGCTTTCGACAATTTAAAGAAAGCTAAATAAAAATGTAGACATGGCTGGCGCAGTGGCTCATGCTT
GTAATCCTAGCACTTTTTGAGGCCAAGGTAGGAGGATTGCTTGAGTCCGGGAGCTCAAGGCAAAGCTGCACAACATAACAAGACCCTATC
TCCACAAAAAAAATGAAAAATAAACCTGGGTGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGATGTGGGCAGATCACAAG
GTCAGGAGTTCAAGACCAGCCTGGCCAACATAGTGAAACCCCATCTCTACTGAAAATACAAAAATTAGCTGGGTGTGGTGGCACGTGCCT

>89160_89160_5_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000448281_FANCD2_chr3_10122784_ENST00000287647_length(amino acids)=617AA_BP=136
MASERGKVKHNWSSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNSSSSFSPHFLG
PGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEEEACSLKNKGSRNIGFSHLQQRSAQEIVHCVFQLLTPMCNHLENIHNYF
QCLAAENHGVVDGPGVKVQEYHIMSSCYQRLLQIFHGLFAWSGFSQPENQNLLYSALHVLSSRLKQGEHSQPLEELLSQSVHYLQNFHQS
IPSFQCALYLIRLLMVILEKSTASAQNKEKIASLARQFLCRVWPSGDKEKSNISNDQLHALLCIYLEHTESILKAIEEIAGVGVPELINS
PKDASSSTFPTLTRHTFVVFFRVMMAELEKTVKKIEPGTAADSQQIHEEKLLYWNMAVRDFSILINLIKVFDSHPVLHVCLKYGRLFVEA
FLKQCMPLLDFSFRKHREDVLSLLETFQLDTRLLHHLCGHSKIHQDTRLTQHVPLLKKTLELLVCRVKAMLTLNNCREAFWLGNLKNRDL

--------------------------------------------------------------
>89160_89160_6_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000448281_FANCD2_chr3_10122784_ENST00000383806_length(transcript)=2530nt_BP=576nt
GGCAAAGTGAAGGCTTCCTGATCTCAGAAGCACGTTGTGGGCTTGGAAACCGACGGCAGCCTTTAGTCAATTTTGGATCGCTTTGACTTC
TCCAACACGGTTTGGCATCTCTGAAACCTTGAGAACTGTGATGGGCAGTGGAAAGAAGAGGGAAAGGTGCCCATGGCGTCCGAGCGGGGC
AAGGTCAAGCACAACTGGAGCAGCACGTCGGAAGGGTGTCCCCGCAAGCGCAGCTGCCTCCGGGAGCCCTGTGATGTGGCCCCCTCCAGC
CGGCCAGCTCAGAGGTCTGCGTCGCGTTCTGGAGGGCCCAGCAGCCCCAAGCGCCTGAAAGCCCAGAAGGAGGACGATGTGGCTTGCTCG
CGGAGGTTATCCTGGGGCTCATCCCGCCGCAGAAATAACTCCTCCTCCTCCTTCTCCCCACATTTCTTGGGCCCTGGTGTGGGCGGGGCC
GCCTCCAAAGGCTGCCTGATTCGGAACACTCGGGGGTTCCTGTCTTCAGGGGGATCCCCTCTGCGTCCTGCCAACGCCTCTTTGGAAGAA
ATGGCTTCTCTAGAGGAGGAAGCCTGCAGCCTTAAGAACAAAGGAAGCCGGAATATTGGATTCTCACATCTCCAACAGAGATCTGCCCAA
GAAATTGTTCATTGTGTTTTTCAACTGCTGACCCCAATGTGTAACCACCTGGAGAACATTCACAACTATTTTCAGTGTTTAGCTGCTGAG
AATCACGGTGTAGTTGATGGACCAGGAGTGAAAGTTCAGGAGTACCACATAATGTCTTCCTGCTATCAGAGGCTGCTGCAGATTTTTCAT
GGGCTTTTTGCTTGGAGTGGATTTTCTCAACCTGAAAATCAGAATTTACTGTATTCAGCCCTCCATGTCCTTAGTAGCCGACTGAAACAG
GGAGAACACAGCCAGCCTTTGGAGGAACTACTCAGCCAGAGCGTCCATTACTTGCAGAATTTCCATCAAAGCATTCCCAGTTTCCAGTGT
GCTCTTTATCTCATCAGACTTTTGATGGTTATTTTGGAGAAATCAACAGCTTCTGCTCAGAACAAAGAAAAAATTGCTTCCCTTGCCAGA
CAATTCCTCTGTCGGGTGTGGCCAAGTGGGGATAAAGAGAAGAGCAACATCTCTAATGACCAGCTCCATGCTCTGCTCTGTATCTACCTG
GAGCACACAGAGAGCATTCTGAAGGCCATAGAGGAGATTGCTGGTGTTGGTGTCCCAGAACTGATCAACTCTCCTAAAGATGCATCTTCC
TCCACATTCCCTACACTGACCAGATTCATGAAGAGAAACTCCTCTACTGGAACATGGCTGTTCGAGACTTCAGTATCCTCATCAACTTGA
TAAAGGTATTTGATAGTCATCCTGTTCTGCATGTATGTTTGAAGTATGGGCGTCTCTTTGTGGAAGCATTTCTGAAGCAATGTATGCCGC
TCCTAGACTTCAGTTTTAGAAAACACCGGGAAGATGTTCTGAGCTTACTGGAAACCTTCCAGTTGGACACAAGGCTGCTTCATCACCTGT
GTGGGCATTCCAAGATTCACCAGGACACGAGACTCACCCAACATGTGCCTCTGCTCAAAAAGACCCTGGAACTTTTAGTTTGCAGAGTCA
AAGCTATGCTCACTCTCAACAATTGTAGAGAGGCTTTCTGGCTGGGCAATCTAAAAAACCGGGACTTGCAGGGTGAAGAGATTAAGTCCC
AAAATTCCCAGGAGAGCACAGCAGATGAGAGTGAGGATGACATGTCATCCCAGGCCTCCAAGAGCAAAGCCACTGAGGATGGTGAAGAAG
ACGAAGTAAGTGCTGGAGAAAAGGAGCAAGATAGTGATGAGAGTTATGATGACTCTGATTAGACCCCAGATAAATTGTTGCCTGCTTCTG
TGTCTCTGCCAGCCTGTGATCATTTTGTGTTAGAGTTTGAAATCCGCTGTTTGCCTTTCTTACTGGTAGGATCCTTTTTTGTTCCTCTTT
TTTTTTTTTTTTTTTTTTTTTTAAAGACGGGGACTCGCTGTGTTTCCCAGGCTGGAGTGCAGTGCTGCAATCTTGGCTCACTGCAACCTC
CATCTCCTAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACGACAGGCACATGCCACCATGCCCAGCTAATTTTTGTA
TTTTTAGTAGATACGGGGTTTTACCATGTCGGCCAGATGGTCTCAATCTCCTGAACTCATGATCCACCTGCCTCAGCCTCCCAAAGTGCT
GGGATTACAGGCATGAGCCACCGCTCCCAGCCATATTTTGTTCTTAAAGTGGGGTCTTTATTAACTTGTGGACATCATGGATTGTCTAAC
ACCATCACAGTCCCTGGCTCAGGATTCTAATGTAGCATTATTTATTGGTTTGGATAAACCCAGCTGTGCTACACTGCAGAGTAAAATCTC
TGAGTCATGATTCTGGACTTTGGGAGCTAGTTTTGAAACTCTGATTTATTGTAGAACTTAGGCTTGTACCAATTTTACAAATAAATTCTG

>89160_89160_6_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000448281_FANCD2_chr3_10122784_ENST00000383806_length(amino acids)=395AA_BP=136
MASERGKVKHNWSSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNSSSSFSPHFLG
PGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEEEACSLKNKGSRNIGFSHLQQRSAQEIVHCVFQLLTPMCNHLENIHNYF
QCLAAENHGVVDGPGVKVQEYHIMSSCYQRLLQIFHGLFAWSGFSQPENQNLLYSALHVLSSRLKQGEHSQPLEELLSQSVHYLQNFHQS
IPSFQCALYLIRLLMVILEKSTASAQNKEKIASLARQFLCRVWPSGDKEKSNISNDQLHALLCIYLEHTESILKAIEEIAGVGVPELINS

--------------------------------------------------------------
>89160_89160_7_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000448281_FANCD2_chr3_10122784_ENST00000383807_length(transcript)=2624nt_BP=576nt
GGCAAAGTGAAGGCTTCCTGATCTCAGAAGCACGTTGTGGGCTTGGAAACCGACGGCAGCCTTTAGTCAATTTTGGATCGCTTTGACTTC
TCCAACACGGTTTGGCATCTCTGAAACCTTGAGAACTGTGATGGGCAGTGGAAAGAAGAGGGAAAGGTGCCCATGGCGTCCGAGCGGGGC
AAGGTCAAGCACAACTGGAGCAGCACGTCGGAAGGGTGTCCCCGCAAGCGCAGCTGCCTCCGGGAGCCCTGTGATGTGGCCCCCTCCAGC
CGGCCAGCTCAGAGGTCTGCGTCGCGTTCTGGAGGGCCCAGCAGCCCCAAGCGCCTGAAAGCCCAGAAGGAGGACGATGTGGCTTGCTCG
CGGAGGTTATCCTGGGGCTCATCCCGCCGCAGAAATAACTCCTCCTCCTCCTTCTCCCCACATTTCTTGGGCCCTGGTGTGGGCGGGGCC
GCCTCCAAAGGCTGCCTGATTCGGAACACTCGGGGGTTCCTGTCTTCAGGGGGATCCCCTCTGCGTCCTGCCAACGCCTCTTTGGAAGAA
ATGGCTTCTCTAGAGGAGGAAGCCTGCAGCCTTAAGAACAAAGGAAGCCGGAATATTGGATTCTCACATCTCCAACAGAGATCTGCCCAA
GAAATTGTTCATTGTGTTTTTCAACTGCTGACCCCAATGTGTAACCACCTGGAGAACATTCACAACTATTTTCAGTGTTTAGCTGCTGAG
AATCACGGTGTAGTTGATGGACCAGGAGTGAAAGTTCAGGAGTACCACATAATGTCTTCCTGCTATCAGAGGCTGCTGCAGATTTTTCAT
GGGCTTTTTGCTTGGAGTGGATTTTCTCAACCTGAAAATCAGAATTTACTGTATTCAGCCCTCCATGTCCTTAGTAGCCGACTGAAACAG
GGAGAACACAGCCAGCCTTTGGAGGAACTACTCAGCCAGAGCGTCCATTACTTGCAGAATTTCCATCAAAGCATTCCCAGTTTCCAGTGT
GCTCTTTATCTCATCAGACTTTTGATGGTTATTTTGGAGAAATCAACAGCTTCTGCTCAGAACAAAGAAAAAATTGCTTCCCTTGCCAGA
CAATTCCTCTGTCGGGTGTGGCCAAGTGGGGATAAAGAGAAGAGCAACATCTCTAATGACCAGCTCCATGCTCTGCTCTGTATCTACCTG
GAGCACACAGAGAGCATTCTGAAGGCCATAGAGGAGATTGCTGGTGTTGGTGTCCCAGAACTGATCAACTCTCCTAAAGATGCATCTTCC
TCCACATTCCCTACACTGACCAGGCATACTTTTGTTGTTTTCTTCCGTGTGATGATGGCTGAACTAGAGAAGACGGTGAAAAAAATTGAG
CCTGGCACAGCAGCAGACTCGCAGCAGATTCATGAAGAGAAACTCCTCTACTGGAACATGGCTGTTCGAGACTTCAGTATCCTCATCAAC
TTGATAAAGGTATTTGATAGTCATCCTGTTCTGCATGTATGTTTGAAGTATGGGCGTCTCTTTGTGGAAGCATTTCTGAAGCAATGTATG
CCGCTCCTAGACTTCAGTTTTAGAAAACACCGGGAAGATGTTCTGAGCTTACTGGAAACCTTCCAGTTGGACACAAGGCTGCTTCATCAC
CTGTGTGGGCATTCCAAGATTCACCAGGACACGAGACTCACCCAACATGTGCCTCTGCTCAAAAAGACCCTGGAACTTTTAGTTTGCAGA
GTCAAAGCTATGCTCACTCTCAACAATTGTAGAGAGGCTTTCTGGCTGGGCAATCTAAAAAACCGGGACTTGCAGGGTGAAGAGATTAAG
TCCCAAAATTCCCAGGAGAGCACAGCAGATGAGAGTGAGGATGACATGTCATCCCAGGCCTCCAAGAGCAAAGCCACTGAGGATGGTGAA
GAAGACGAAGTAAGTGCTGGAGAAAAGGAGCAAGATAGTGATGAGAGTTATGATGACTCTGATTAGACCCCAGATAAATTGTTGCCTGCT
TCTGTGTCTCTGCCAGCCTGTGATCATTTTGTGTTAGAGTTTGAAATCCGCTGTTTGCCTTTCTTACTGGTAGGATCCTTTTTTGTTCCT
CTTTTTTTTTTTTTTTTTTTTTTTTTAAAGACGGGGACTCGCTGTGTTTCCCAGGCTGGAGTGCAGTGCTGCAATCTTGGCTCACTGCAA
CCTCCATCTCCTAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACGACAGGCACATGCCACCATGCCCAGCTAATTTT
TGTATTTTTAGTAGATACGGGGTTTTACCATGTCGGCCAGATGGTCTCAATCTCCTGAACTCATGATCCACCTGCCTCAGCCTCCCAAAG
TGCTGGGATTACAGGCATGAGCCACCGCTCCCAGCCATATTTTGTTCTTAAAGTGGGGTCTTTATTAACTTGTGGACATCATGGATTGTC
TAACACCATCACAGTCCCTGGCTCAGGATTCTAATGTAGCATTATTTATTGGTTTGGATAAACCCAGCTGTGCTACACTGCAGAGTAAAA
TCTCTGAGTCATGATTCTGGACTTTGGGAGCTAGTTTTGAAACTCTGATTTATTGTAGAACTTAGGCTTGTACCAATTTTACAAATAAAT

>89160_89160_7_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000448281_FANCD2_chr3_10122784_ENST00000383807_length(amino acids)=597AA_BP=136
MASERGKVKHNWSSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNSSSSFSPHFLG
PGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEEEACSLKNKGSRNIGFSHLQQRSAQEIVHCVFQLLTPMCNHLENIHNYF
QCLAAENHGVVDGPGVKVQEYHIMSSCYQRLLQIFHGLFAWSGFSQPENQNLLYSALHVLSSRLKQGEHSQPLEELLSQSVHYLQNFHQS
IPSFQCALYLIRLLMVILEKSTASAQNKEKIASLARQFLCRVWPSGDKEKSNISNDQLHALLCIYLEHTESILKAIEEIAGVGVPELINS
PKDASSSTFPTLTRHTFVVFFRVMMAELEKTVKKIEPGTAADSQQIHEEKLLYWNMAVRDFSILINLIKVFDSHPVLHVCLKYGRLFVEA
FLKQCMPLLDFSFRKHREDVLSLLETFQLDTRLLHHLCGHSKIHQDTRLTQHVPLLKKTLELLVCRVKAMLTLNNCREAFWLGNLKNRDL

--------------------------------------------------------------
>89160_89160_8_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000448281_FANCD2_chr3_10122784_ENST00000419585_length(transcript)=2624nt_BP=576nt
GGCAAAGTGAAGGCTTCCTGATCTCAGAAGCACGTTGTGGGCTTGGAAACCGACGGCAGCCTTTAGTCAATTTTGGATCGCTTTGACTTC
TCCAACACGGTTTGGCATCTCTGAAACCTTGAGAACTGTGATGGGCAGTGGAAAGAAGAGGGAAAGGTGCCCATGGCGTCCGAGCGGGGC
AAGGTCAAGCACAACTGGAGCAGCACGTCGGAAGGGTGTCCCCGCAAGCGCAGCTGCCTCCGGGAGCCCTGTGATGTGGCCCCCTCCAGC
CGGCCAGCTCAGAGGTCTGCGTCGCGTTCTGGAGGGCCCAGCAGCCCCAAGCGCCTGAAAGCCCAGAAGGAGGACGATGTGGCTTGCTCG
CGGAGGTTATCCTGGGGCTCATCCCGCCGCAGAAATAACTCCTCCTCCTCCTTCTCCCCACATTTCTTGGGCCCTGGTGTGGGCGGGGCC
GCCTCCAAAGGCTGCCTGATTCGGAACACTCGGGGGTTCCTGTCTTCAGGGGGATCCCCTCTGCGTCCTGCCAACGCCTCTTTGGAAGAA
ATGGCTTCTCTAGAGGAGGAAGCCTGCAGCCTTAAGAACAAAGGAAGCCGGAATATTGGATTCTCACATCTCCAACAGAGATCTGCCCAA
GAAATTGTTCATTGTGTTTTTCAACTGCTGACCCCAATGTGTAACCACCTGGAGAACATTCACAACTATTTTCAGTGTTTAGCTGCTGAG
AATCACGGTGTAGTTGATGGACCAGGAGTGAAAGTTCAGGAGTACCACATAATGTCTTCCTGCTATCAGAGGCTGCTGCAGATTTTTCAT
GGGCTTTTTGCTTGGAGTGGATTTTCTCAACCTGAAAATCAGAATTTACTGTATTCAGCCCTCCATGTCCTTAGTAGCCGACTGAAACAG
GGAGAACACAGCCAGCCTTTGGAGGAACTACTCAGCCAGAGCGTCCATTACTTGCAGAATTTCCATCAAAGCATTCCCAGTTTCCAGTGT
GCTCTTTATCTCATCAGACTTTTGATGGTTATTTTGGAGAAATCAACAGCTTCTGCTCAGAACAAAGAAAAAATTGCTTCCCTTGCCAGA
CAATTCCTCTGTCGGGTGTGGCCAAGTGGGGATAAAGAGAAGAGCAACATCTCTAATGACCAGCTCCATGCTCTGCTCTGTATCTACCTG
GAGCACACAGAGAGCATTCTGAAGGCCATAGAGGAGATTGCTGGTGTTGGTGTCCCAGAACTGATCAACTCTCCTAAAGATGCATCTTCC
TCCACATTCCCTACACTGACCAGGCATACTTTTGTTGTTTTCTTCCGTGTGATGATGGCTGAACTAGAGAAGACGGTGAAAAAAATTGAG
CCTGGCACAGCAGCAGACTCGCAGCAGATTCATGAAGAGAAACTCCTCTACTGGAACATGGCTGTTCGAGACTTCAGTATCCTCATCAAC
TTGATAAAGGTATTTGATAGTCATCCTGTTCTGCATGTATGTTTGAAGTATGGGCGTCTCTTTGTGGAAGCATTTCTGAAGCAATGTATG
CCGCTCCTAGACTTCAGTTTTAGAAAACACCGGGAAGATGTTCTGAGCTTACTGGAAACCTTCCAGTTGGACACAAGGCTGCTTCATCAC
CTGTGTGGGCATTCCAAGATTCACCAGGACACGAGACTCACCCAACATGTGCCTCTGCTCAAAAAGACCCTGGAACTTTTAGTTTGCAGA
GTCAAAGCTATGCTCACTCTCAACAATTGTAGAGAGGCTTTCTGGCTGGGCAATCTAAAAAACCGGGACTTGCAGGGTGAAGAGATTAAG
TCCCAAAATTCCCAGGAGAGCACAGCAGATGAGAGTGAGGATGACATGTCATCCCAGGCCTCCAAGAGCAAAGCCACTGAGGATGGTGAA
GAAGACGAAGTAAGTGCTGGAGAAAAGGAGCAAGATAGTGATGAGAGTTATGATGACTCTGATTAGACCCCAGATAAATTGTTGCCTGCT
TCTGTGTCTCTGCCAGCCTGTGATCATTTTGTGTTAGAGTTTGAAATCCGCTGTTTGCCTTTCTTACTGGTAGGATCCTTTTTTGTTCCT
CTTTTTTTTTTTTTTTTTTTTTTTTTAAAGACGGGGACTCGCTGTGTTTCCCAGGCTGGAGTGCAGTGCTGCAATCTTGGCTCACTGCAA
CCTCCATCTCCTAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACGACAGGCACATGCCACCATGCCCAGCTAATTTT
TGTATTTTTAGTAGATACGGGGTTTTACCATGTCGGCCAGATGGTCTCAATCTCCTGAACTCATGATCCACCTGCCTCAGCCTCCCAAAG
TGCTGGGATTACAGGCATGAGCCACCGCTCCCAGCCATATTTTGTTCTTAAAGTGGGGTCTTTATTAACTTGTGGACATCATGGATTGTC
TAACACCATCACAGTCCCTGGCTCAGGATTCTAATGTAGCATTATTTATTGGTTTGGATAAACCCAGCTGTGCTACACTGCAGAGTAAAA
TCTCTGAGTCATGATTCTGGACTTTGGGAGCTAGTTTTGAAACTCTGATTTATTGTAGAACTTAGGCTTGTACCAATTTTACAAATAAAT

>89160_89160_8_TATDN2-FANCD2_TATDN2_chr3_10291298_ENST00000448281_FANCD2_chr3_10122784_ENST00000419585_length(amino acids)=597AA_BP=136
MASERGKVKHNWSSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNSSSSFSPHFLG
PGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEEEACSLKNKGSRNIGFSHLQQRSAQEIVHCVFQLLTPMCNHLENIHNYF
QCLAAENHGVVDGPGVKVQEYHIMSSCYQRLLQIFHGLFAWSGFSQPENQNLLYSALHVLSSRLKQGEHSQPLEELLSQSVHYLQNFHQS
IPSFQCALYLIRLLMVILEKSTASAQNKEKIASLARQFLCRVWPSGDKEKSNISNDQLHALLCIYLEHTESILKAIEEIAGVGVPELINS
PKDASSSTFPTLTRHTFVVFFRVMMAELEKTVKKIEPGTAADSQQIHEEKLLYWNMAVRDFSILINLIKVFDSHPVLHVCLKYGRLFVEA
FLKQCMPLLDFSFRKHREDVLSLLETFQLDTRLLHHLCGHSKIHQDTRLTQHVPLLKKTLELLVCRVKAMLTLNNCREAFWLGNLKNRDL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TATDN2-FANCD2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneFANCD2chr3:10291298chr3:10122784ENST0000043169308248_3590242.0BRCA2
TgeneFANCD2chr3:10291298chr3:10122784ENST00000431693081_2910242.0FANCE


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneFANCD2chr3:10291298chr3:10122784ENST000002876472943248_359992.01472.0BRCA2
TgeneFANCD2chr3:10291298chr3:10122784ENST000003838062943248_359992.01469.6666666666667BRCA2
TgeneFANCD2chr3:10291298chr3:10122784ENST000003838072944248_359992.01452.0BRCA2
TgeneFANCD2chr3:10291298chr3:10122784ENST000004195852944248_359992.01452.0BRCA2
TgeneFANCD2chr3:10291298chr3:10122784ENST0000028764729431_291992.01472.0FANCE
TgeneFANCD2chr3:10291298chr3:10122784ENST0000038380629431_291992.01469.6666666666667FANCE
TgeneFANCD2chr3:10291298chr3:10122784ENST0000038380729441_291992.01452.0FANCE
TgeneFANCD2chr3:10291298chr3:10122784ENST0000041958529441_291992.01452.0FANCE


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TATDN2-FANCD2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TATDN2-FANCD2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource