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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BAIAP2L1-MET (FusionGDB2 ID:8923)

Fusion Gene Summary for BAIAP2L1-MET

check button Fusion gene summary
Fusion gene informationFusion gene name: BAIAP2L1-MET
Fusion gene ID: 8923
HgeneTgene
Gene symbol

BAIAP2L1

MET

Gene ID

55971

8731

Gene nameBAR/IMD domain containing adaptor protein 2 like 1RNA guanine-7 methyltransferase
SynonymsIRTKSCMT1|CMT1c|MET|Met|RG7MT1|cm1p|hCMT1|hMet
Cytomap

7q21.3-q22.1

18p11.21

Type of geneprotein-codingprotein-coding
Descriptionbrain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1BAI1 associated protein 2 like 1BAI1-associated protein 2-like protein 1insulin receptor tyrosine kinase substratemRNA cap guanine-N7 methyltransferaseRNA (guanine-7-) methyltransferasehcm1pmRNA (guanine-7-)methyltransferasemRNA (guanine-N(7)-)-methyltransferasemRNA cap methyltransferase
Modification date2020031320200329
UniProtAcc

Q9UHR4

Q9H1A3

Ensembl transtripts involved in fusion geneENST00000005260, ENST00000462558, 
ENST00000436117, ENST00000495962, 
ENST00000539704, ENST00000318493, 
ENST00000397752, 
Fusion gene scores* DoF score20 X 13 X 9=234014 X 18 X 10=2520
# samples 2327
** MAII scorelog2(23/2340*10)=-3.34680276352639
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(27/2520*10)=-3.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BAIAP2L1 [Title/Abstract] AND MET [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBAIAP2L1(97939757)-MET(116414935), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneBAIAP2L1

GO:0009617

response to bacterium

19366662

HgeneBAIAP2L1

GO:0030838

positive regulation of actin filament polymerization

21098279

TgeneMET

GO:0006370

7-methylguanosine mRNA capping

27422871


check buttonFusion gene breakpoints across BAIAP2L1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MET (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4KIRPTCGA-BQ-7049-01ABAIAP2L1chr7

97939757

-METchr7

116414935

+
ChimerDB4KIRPTCGA-BQ-7049BAIAP2L1chr7

97939756

-METchr7

116414934

+
ChimerDB4KIRPTCGA-BQ-7049BAIAP2L1chr7

97939757

-METchr7

116414935

+


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Fusion Gene ORF analysis for BAIAP2L1-MET

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000005260ENST00000436117BAIAP2L1chr7

97939757

-METchr7

116414935

+
5CDS-intronENST00000005260ENST00000436117BAIAP2L1chr7

97939756

-METchr7

116414934

+
5CDS-intronENST00000005260ENST00000495962BAIAP2L1chr7

97939757

-METchr7

116414935

+
5CDS-intronENST00000005260ENST00000495962BAIAP2L1chr7

97939756

-METchr7

116414934

+
5CDS-intronENST00000005260ENST00000539704BAIAP2L1chr7

97939757

-METchr7

116414935

+
5CDS-intronENST00000005260ENST00000539704BAIAP2L1chr7

97939756

-METchr7

116414934

+
5UTR-3CDSENST00000462558ENST00000318493BAIAP2L1chr7

97939757

-METchr7

116414935

+
5UTR-3CDSENST00000462558ENST00000318493BAIAP2L1chr7

97939756

-METchr7

116414934

+
5UTR-3CDSENST00000462558ENST00000397752BAIAP2L1chr7

97939757

-METchr7

116414935

+
5UTR-3CDSENST00000462558ENST00000397752BAIAP2L1chr7

97939756

-METchr7

116414934

+
5UTR-intronENST00000462558ENST00000436117BAIAP2L1chr7

97939757

-METchr7

116414935

+
5UTR-intronENST00000462558ENST00000436117BAIAP2L1chr7

97939756

-METchr7

116414934

+
5UTR-intronENST00000462558ENST00000495962BAIAP2L1chr7

97939757

-METchr7

116414935

+
5UTR-intronENST00000462558ENST00000495962BAIAP2L1chr7

97939756

-METchr7

116414934

+
5UTR-intronENST00000462558ENST00000539704BAIAP2L1chr7

97939757

-METchr7

116414935

+
5UTR-intronENST00000462558ENST00000539704BAIAP2L1chr7

97939756

-METchr7

116414934

+
In-frameENST00000005260ENST00000318493BAIAP2L1chr7

97939757

-METchr7

116414935

+
In-frameENST00000005260ENST00000318493BAIAP2L1chr7

97939756

-METchr7

116414934

+
In-frameENST00000005260ENST00000397752BAIAP2L1chr7

97939757

-METchr7

116414935

+
In-frameENST00000005260ENST00000397752BAIAP2L1chr7

97939756

-METchr7

116414934

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000005260BAIAP2L1chr797939757-ENST00000397752METchr7116414935+45781171332315760
ENST00000005260BAIAP2L1chr797939757-ENST00000318493METchr7116414935+25341171332315760
ENST00000005260BAIAP2L1chr797939756-ENST00000397752METchr7116414934+45781171332315760
ENST00000005260BAIAP2L1chr797939756-ENST00000318493METchr7116414934+25341171332315760

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000005260ENST00000397752BAIAP2L1chr797939757-METchr7116414935+0.0002138120.9997862
ENST00000005260ENST00000318493BAIAP2L1chr797939757-METchr7116414935+0.0008111310.99918884
ENST00000005260ENST00000397752BAIAP2L1chr797939756-METchr7116414934+0.0002138120.9997862
ENST00000005260ENST00000318493BAIAP2L1chr797939756-METchr7116414934+0.0008111310.99918884

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Fusion Genomic Features for BAIAP2L1-MET


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
BAIAP2L1chr797939756-METchr7116414934+0.0056651440.99433494
BAIAP2L1chr797939756-METchr7116414934+0.0056651440.99433494
BAIAP2L1chr797939756-METchr7116414934+0.0056651440.99433494
BAIAP2L1chr797939756-METchr7116414934+0.0056651440.99433494

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for BAIAP2L1-MET


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:97939757/chr7:116414935)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BAIAP2L1

Q9UHR4

MET

Q9H1A3

FUNCTION: May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. {ECO:0000269|PubMed:17430976, ECO:0000269|PubMed:19366662, ECO:0000269|PubMed:22921828}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBAIAP2L1chr7:97939756chr7:116414934ENST00000005260-914115_154318512.0Coiled coilOntology_term=ECO:0000255
HgeneBAIAP2L1chr7:97939757chr7:116414935ENST00000005260-914115_154318512.0Coiled coilOntology_term=ECO:0000255
HgeneBAIAP2L1chr7:97939756chr7:116414934ENST00000005260-9141_249318512.0DomainIMD
HgeneBAIAP2L1chr7:97939757chr7:116414935ENST00000005260-9141_249318512.0DomainIMD
TgeneMETchr7:97939756chr7:116414934ENST0000031849313211078_134510271409.0DomainProtein kinase
TgeneMETchr7:97939756chr7:116414934ENST0000039775213211078_134510091391.0DomainProtein kinase
TgeneMETchr7:97939756chr7:116414934ENST00000436117091078_13450765.0DomainProtein kinase
TgeneMETchr7:97939756chr7:116414934ENST000004361170927_5150765.0DomainSema
TgeneMETchr7:97939756chr7:116414934ENST0000043611709563_6550765.0DomainNote=IPT/TIG 1
TgeneMETchr7:97939756chr7:116414934ENST0000043611709657_7390765.0DomainNote=IPT/TIG 2
TgeneMETchr7:97939756chr7:116414934ENST0000043611709742_8360765.0DomainNote=IPT/TIG 3
TgeneMETchr7:97939757chr7:116414935ENST0000031849313211078_134510271409.0DomainProtein kinase
TgeneMETchr7:97939757chr7:116414935ENST0000039775213211078_134510091391.0DomainProtein kinase
TgeneMETchr7:97939757chr7:116414935ENST00000436117091078_13450765.0DomainProtein kinase
TgeneMETchr7:97939757chr7:116414935ENST000004361170927_5150765.0DomainSema
TgeneMETchr7:97939757chr7:116414935ENST0000043611709563_6550765.0DomainNote=IPT/TIG 1
TgeneMETchr7:97939757chr7:116414935ENST0000043611709657_7390765.0DomainNote=IPT/TIG 2
TgeneMETchr7:97939757chr7:116414935ENST0000043611709742_8360765.0DomainNote=IPT/TIG 3
TgeneMETchr7:97939756chr7:116414934ENST0000031849313211084_109210271409.0Nucleotide bindingATP
TgeneMETchr7:97939756chr7:116414934ENST0000039775213211084_109210091391.0Nucleotide bindingATP
TgeneMETchr7:97939756chr7:116414934ENST00000436117091084_10920765.0Nucleotide bindingATP
TgeneMETchr7:97939757chr7:116414935ENST0000031849313211084_109210271409.0Nucleotide bindingATP
TgeneMETchr7:97939757chr7:116414935ENST0000039775213211084_109210091391.0Nucleotide bindingATP
TgeneMETchr7:97939757chr7:116414935ENST00000436117091084_10920765.0Nucleotide bindingATP
TgeneMETchr7:97939756chr7:116414934ENST000004361170925_9320765.0Topological domainExtracellular
TgeneMETchr7:97939756chr7:116414934ENST0000043611709956_13900765.0Topological domainCytoplasmic
TgeneMETchr7:97939757chr7:116414935ENST000004361170925_9320765.0Topological domainExtracellular
TgeneMETchr7:97939757chr7:116414935ENST0000043611709956_13900765.0Topological domainCytoplasmic
TgeneMETchr7:97939756chr7:116414934ENST0000043611709933_9550765.0TransmembraneHelical
TgeneMETchr7:97939757chr7:116414935ENST0000043611709933_9550765.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBAIAP2L1chr7:97939756chr7:116414934ENST00000005260-914339_402318512.0DomainSH3
HgeneBAIAP2L1chr7:97939757chr7:116414935ENST00000005260-914339_402318512.0DomainSH3
HgeneBAIAP2L1chr7:97939756chr7:116414934ENST00000005260-914483_511318512.0RegionNote=Binds F-actin
HgeneBAIAP2L1chr7:97939757chr7:116414935ENST00000005260-914483_511318512.0RegionNote=Binds F-actin
TgeneMETchr7:97939756chr7:116414934ENST00000318493132127_51510271409.0DomainSema
TgeneMETchr7:97939756chr7:116414934ENST000003184931321563_65510271409.0DomainNote=IPT/TIG 1
TgeneMETchr7:97939756chr7:116414934ENST000003184931321657_73910271409.0DomainNote=IPT/TIG 2
TgeneMETchr7:97939756chr7:116414934ENST000003184931321742_83610271409.0DomainNote=IPT/TIG 3
TgeneMETchr7:97939756chr7:116414934ENST00000397752132127_51510091391.0DomainSema
TgeneMETchr7:97939756chr7:116414934ENST000003977521321563_65510091391.0DomainNote=IPT/TIG 1
TgeneMETchr7:97939756chr7:116414934ENST000003977521321657_73910091391.0DomainNote=IPT/TIG 2
TgeneMETchr7:97939756chr7:116414934ENST000003977521321742_83610091391.0DomainNote=IPT/TIG 3
TgeneMETchr7:97939757chr7:116414935ENST00000318493132127_51510271409.0DomainSema
TgeneMETchr7:97939757chr7:116414935ENST000003184931321563_65510271409.0DomainNote=IPT/TIG 1
TgeneMETchr7:97939757chr7:116414935ENST000003184931321657_73910271409.0DomainNote=IPT/TIG 2
TgeneMETchr7:97939757chr7:116414935ENST000003184931321742_83610271409.0DomainNote=IPT/TIG 3
TgeneMETchr7:97939757chr7:116414935ENST00000397752132127_51510091391.0DomainSema
TgeneMETchr7:97939757chr7:116414935ENST000003977521321563_65510091391.0DomainNote=IPT/TIG 1
TgeneMETchr7:97939757chr7:116414935ENST000003977521321657_73910091391.0DomainNote=IPT/TIG 2
TgeneMETchr7:97939757chr7:116414935ENST000003977521321742_83610091391.0DomainNote=IPT/TIG 3
TgeneMETchr7:97939756chr7:116414934ENST00000318493132125_93210271409.0Topological domainExtracellular
TgeneMETchr7:97939756chr7:116414934ENST000003184931321956_139010271409.0Topological domainCytoplasmic
TgeneMETchr7:97939756chr7:116414934ENST00000397752132125_93210091391.0Topological domainExtracellular
TgeneMETchr7:97939756chr7:116414934ENST000003977521321956_139010091391.0Topological domainCytoplasmic
TgeneMETchr7:97939757chr7:116414935ENST00000318493132125_93210271409.0Topological domainExtracellular
TgeneMETchr7:97939757chr7:116414935ENST000003184931321956_139010271409.0Topological domainCytoplasmic
TgeneMETchr7:97939757chr7:116414935ENST00000397752132125_93210091391.0Topological domainExtracellular
TgeneMETchr7:97939757chr7:116414935ENST000003977521321956_139010091391.0Topological domainCytoplasmic
TgeneMETchr7:97939756chr7:116414934ENST000003184931321933_95510271409.0TransmembraneHelical
TgeneMETchr7:97939756chr7:116414934ENST000003977521321933_95510091391.0TransmembraneHelical
TgeneMETchr7:97939757chr7:116414935ENST000003184931321933_95510271409.0TransmembraneHelical
TgeneMETchr7:97939757chr7:116414935ENST000003977521321933_95510091391.0TransmembraneHelical


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Fusion Gene Sequence for BAIAP2L1-MET


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8923_8923_1_BAIAP2L1-MET_BAIAP2L1_chr7_97939756_ENST00000005260_MET_chr7_116414934_ENST00000318493_length(transcript)=2534nt_BP=1171nt
CTCCTCTGCTCCTCGAAGAAGGCCAGGGCGGCGCTGCCGCAAGTTTTGACATTTTCGCAGCGGAGACGCGCGCGGGCACTCTCGGGCCGA
CGGCTGCGGCGGCGGCCGACCCTCCAGAGCCCCTTAGTCGCGCCCCGGCCCTCCCGCTGCCCGGAGTCCGGCGGCCACGAGGCCCAGCCG
CGTCCTCCCGCGCTTGCTCGCCCGGCGGCCGCAGCCATGTCCCGGGGGCCCGAGGAGGTGAACCGGCTCACGGAGAGCACCTACCGGAAT
GTTATGGAACAGTTCAATCCTGGGCTGCGAAATTTAATAAACCTGGGGAAAAATTATGAGAAAGCTGTAAACGCTATGATCCTGGCAGGA
AAAGCCTACTACGATGGAGTGGCCAAGATCGGTGAGATTGCCACTGGGTCCCCCGTGTCAACTGAACTGGGACATGTCCTCATAGAGATT
TCAAGTACCCACAAGAAACTCAACGAGAGTCTTGATGAAAATTTTAAAAAATTCCACAAAGAGATTATCCATGAGCTGGAGAAGAAGATA
GAACTTGACGTGAAATATATGAACGCAACTCTAAAAAGATACCAAACAGAACACAAGAATAAATTAGAGTCTTTGGAGAAATCCCAAGCT
GAGTTGAAGAAGATCAGAAGGAAAAGCCAAGGAAGCCGAAACGCACTCAAATATGAACACAAAGAAATTGAGTATGTGGAGACCGTTACT
TCTCGTCAGAGTGAAATCCAGAAATTCATTGCAGATGGTTGCAAAGAGGCTCTGCTTGAAGAGAAGAGGCGCTTCTGCTTTCTGGTTGAT
AAGCACTGTGGCTTTGCAAACCACATACATTATTATCACTTACAGTCTGCAGAACTACTGAATTCCAAGCTGCCTCGGTGGCAGGAGACC
TGTGTTGATGCCATCAAAGTGCCAGAGAAAATCATGAATATGATCGAAGAAATAAAGACCCCAGCCTCTACCCCCGTGTCTGGAACTCCT
CAGGCTTCACCCATGATCGAGAGAAGCAATGTGGTTAGGAAAGATTACGACACCCTTTCTAAATGCTCACCAAAGATGCCCCCCGCTCCT
TCAGGCAGAGCATATACCAGTCCCTTGATCGATATGTTTAATAACCCAGCCACGGCTGCCCCGAATTCACAAAGGGTAAATAATTCAACA
GATCAGTTTCCTAATTCATCTCAGAACGGTTCATGCCGACAAGTGCAGTATCCTCTGACAGACATGTCCCCCATCCTAACTAGTGGGGAC
TCTGATATATCCAGTCCATTACTGCAAAATACTGTCCACATTGACCTCAGTGCTCTAAATCCAGAGCTGGTCCAGGCAGTGCAGCATGTA
GTGATTGGGCCCAGTAGCCTGATTGTGCATTTCAATGAAGTCATAGGAAGAGGGCATTTTGGTTGTGTATATCATGGGACTTTGTTGGAC
AATGATGGCAAGAAAATTCACTGTGCTGTGAAATCCTTGAACAGAATCACTGACATAGGAGAAGTTTCCCAATTTCTGACCGAGGGAATC
ATCATGAAAGATTTTAGTCATCCCAATGTCCTCTCGCTCCTGGGAATCTGCCTGCGAAGTGAAGGGTCTCCGCTGGTGGTCCTACCATAC
ATGAAACATGGAGATCTTCGAAATTTCATTCGAAATGAGACTCATAATCCAACTGTAAAAGATCTTATTGGCTTTGGTCTTCAAGTAGCC
AAAGGCATGAAATATCTTGCAAGCAAAAAGTTTGTCCACAGAGACTTGGCTGCAAGAAACTGTATGCTGGATGAAAAATTCACAGTCAAG
GTTGCTGATTTTGGTCTTGCCAGAGACATGTATGATAAAGAATACTATAGTGTACACAACAAAACAGGTGCAAAGCTGCCAGTGAAGTGG
ATGGCTTTGGAAAGTCTGCAAACTCAAAAGTTTACCACCAAGTCAGATGTGTGGTCCTTTGGCGTGCTCCTCTGGGAGCTGATGACAAGA
GGAGCCCCACCTTATCCTGACGTAAACACCTTTGATATAACTGTTTACTTGTTGCAAGGGAGAAGACTCCTACAACCCGAATACTGCCCA
GACCCCTTATATGAAGTAATGCTAAAATGCTGGCACCCTAAAGCCGAAATGCGCCCATCCTTTTCTGAACTGGTGTCCCGGATATCAGCG
ATCTTCTCTACTTTCATTGGGGAGCACTATGTCCATGTGAACGCTACTTATGTGAACGTAAAATGTGTCGCTCCGTATCCTTCTCTGTTG
TCATCAGAAGATAACGCTGATGATGAGGTGGACACACGACCAGCCTCCTTCTGGGAGACATCATAGTGCTAGTACTATGTCAAAGCAACA
GTCCACACTTTGTCCAATGGTTTTTTCACTGCCTGACCTTTAAAAGGCCATCGATATTCTTTGCTCTTGCCAAAATTGCACTATTATAGG
ACTTGTATTGTTATTTAAATTACTGGATTCTAAGGAATTTCTTATCTGACAGAGCATCAGAACCAGAGGCTTGGTCCCACAGGCCACGGA

>8923_8923_1_BAIAP2L1-MET_BAIAP2L1_chr7_97939756_ENST00000005260_MET_chr7_116414934_ENST00000318493_length(amino acids)=760AA_BP=378
MPQVLTFSQRRRARALSGRRLRRRPTLQSPLVAPRPSRCPESGGHEAQPRPPALARPAAAAMSRGPEEVNRLTESTYRNVMEQFNPGLRN
LINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGSPVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATL
KRYQTEHKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEALLEEKRRFCFLVDKHCGFANHIHY
YHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEEIKTPASTPVSGTPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPLID
MFNNPATAAPNSQRVNNSTDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHF
NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIR
NETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF
TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYV

--------------------------------------------------------------
>8923_8923_2_BAIAP2L1-MET_BAIAP2L1_chr7_97939756_ENST00000005260_MET_chr7_116414934_ENST00000397752_length(transcript)=4578nt_BP=1171nt
CTCCTCTGCTCCTCGAAGAAGGCCAGGGCGGCGCTGCCGCAAGTTTTGACATTTTCGCAGCGGAGACGCGCGCGGGCACTCTCGGGCCGA
CGGCTGCGGCGGCGGCCGACCCTCCAGAGCCCCTTAGTCGCGCCCCGGCCCTCCCGCTGCCCGGAGTCCGGCGGCCACGAGGCCCAGCCG
CGTCCTCCCGCGCTTGCTCGCCCGGCGGCCGCAGCCATGTCCCGGGGGCCCGAGGAGGTGAACCGGCTCACGGAGAGCACCTACCGGAAT
GTTATGGAACAGTTCAATCCTGGGCTGCGAAATTTAATAAACCTGGGGAAAAATTATGAGAAAGCTGTAAACGCTATGATCCTGGCAGGA
AAAGCCTACTACGATGGAGTGGCCAAGATCGGTGAGATTGCCACTGGGTCCCCCGTGTCAACTGAACTGGGACATGTCCTCATAGAGATT
TCAAGTACCCACAAGAAACTCAACGAGAGTCTTGATGAAAATTTTAAAAAATTCCACAAAGAGATTATCCATGAGCTGGAGAAGAAGATA
GAACTTGACGTGAAATATATGAACGCAACTCTAAAAAGATACCAAACAGAACACAAGAATAAATTAGAGTCTTTGGAGAAATCCCAAGCT
GAGTTGAAGAAGATCAGAAGGAAAAGCCAAGGAAGCCGAAACGCACTCAAATATGAACACAAAGAAATTGAGTATGTGGAGACCGTTACT
TCTCGTCAGAGTGAAATCCAGAAATTCATTGCAGATGGTTGCAAAGAGGCTCTGCTTGAAGAGAAGAGGCGCTTCTGCTTTCTGGTTGAT
AAGCACTGTGGCTTTGCAAACCACATACATTATTATCACTTACAGTCTGCAGAACTACTGAATTCCAAGCTGCCTCGGTGGCAGGAGACC
TGTGTTGATGCCATCAAAGTGCCAGAGAAAATCATGAATATGATCGAAGAAATAAAGACCCCAGCCTCTACCCCCGTGTCTGGAACTCCT
CAGGCTTCACCCATGATCGAGAGAAGCAATGTGGTTAGGAAAGATTACGACACCCTTTCTAAATGCTCACCAAAGATGCCCCCCGCTCCT
TCAGGCAGAGCATATACCAGTCCCTTGATCGATATGTTTAATAACCCAGCCACGGCTGCCCCGAATTCACAAAGGGTAAATAATTCAACA
GATCAGTTTCCTAATTCATCTCAGAACGGTTCATGCCGACAAGTGCAGTATCCTCTGACAGACATGTCCCCCATCCTAACTAGTGGGGAC
TCTGATATATCCAGTCCATTACTGCAAAATACTGTCCACATTGACCTCAGTGCTCTAAATCCAGAGCTGGTCCAGGCAGTGCAGCATGTA
GTGATTGGGCCCAGTAGCCTGATTGTGCATTTCAATGAAGTCATAGGAAGAGGGCATTTTGGTTGTGTATATCATGGGACTTTGTTGGAC
AATGATGGCAAGAAAATTCACTGTGCTGTGAAATCCTTGAACAGAATCACTGACATAGGAGAAGTTTCCCAATTTCTGACCGAGGGAATC
ATCATGAAAGATTTTAGTCATCCCAATGTCCTCTCGCTCCTGGGAATCTGCCTGCGAAGTGAAGGGTCTCCGCTGGTGGTCCTACCATAC
ATGAAACATGGAGATCTTCGAAATTTCATTCGAAATGAGACTCATAATCCAACTGTAAAAGATCTTATTGGCTTTGGTCTTCAAGTAGCC
AAAGGCATGAAATATCTTGCAAGCAAAAAGTTTGTCCACAGAGACTTGGCTGCAAGAAACTGTATGCTGGATGAAAAATTCACAGTCAAG
GTTGCTGATTTTGGTCTTGCCAGAGACATGTATGATAAAGAATACTATAGTGTACACAACAAAACAGGTGCAAAGCTGCCAGTGAAGTGG
ATGGCTTTGGAAAGTCTGCAAACTCAAAAGTTTACCACCAAGTCAGATGTGTGGTCCTTTGGCGTGCTCCTCTGGGAGCTGATGACAAGA
GGAGCCCCACCTTATCCTGACGTAAACACCTTTGATATAACTGTTTACTTGTTGCAAGGGAGAAGACTCCTACAACCCGAATACTGCCCA
GACCCCTTATATGAAGTAATGCTAAAATGCTGGCACCCTAAAGCCGAAATGCGCCCATCCTTTTCTGAACTGGTGTCCCGGATATCAGCG
ATCTTCTCTACTTTCATTGGGGAGCACTATGTCCATGTGAACGCTACTTATGTGAACGTAAAATGTGTCGCTCCGTATCCTTCTCTGTTG
TCATCAGAAGATAACGCTGATGATGAGGTGGACACACGACCAGCCTCCTTCTGGGAGACATCATAGTGCTAGTACTATGTCAAAGCAACA
GTCCACACTTTGTCCAATGGTTTTTTCACTGCCTGACCTTTAAAAGGCCATCGATATTCTTTGCTCTTGCCAAAATTGCACTATTATAGG
ACTTGTATTGTTATTTAAATTACTGGATTCTAAGGAATTTCTTATCTGACAGAGCATCAGAACCAGAGGCTTGGTCCCACAGGCCACGGA
CCAATGGCCTGCAGCCGTGACAACACTCCTGTCATATTGGAGTCCAAAACTTGAATTCTGGGTTGAATTTTTTAAAAATCAGGTACCACT
TGATTTCATATGGGAAATTGAAGCAGGAAATATTGAGGGCTTCTTGATCACAGAAAACTCAGAAGAGATAGTAATGCTCAGGACAGGAGC
GGCAGCCCCAGAACAGGCCACTCATTTAGAATTCTAGTGTTTCAAAACACTTTTGTGTGTTGTATGGTCAATAACATTTTTCATTACTGA
TGGTGTCATTCACCCATTAGGTAAACATTCCCTTTTAAATGTTTGTTTGTTTTTTGAGACAGGATCTCACTCTGTTGCCAGGGCTGTAGT
GCAGTGGTGTGATCATAGCTCACTGCAACCTCCACCTCCCAGGCTCAAGCCTCCCGAATAGCTGGGACTACAGGCGCACACCACCATCCC
CGGCTAATTTTTGTATTTTTTGTAGAGACGGGGTTTTGCCATGTTGCCAAGGCTGGTTTCAAACTCCTGGACTCAAGAAATCCACCCACC
TCAGCCTCCCAAAGTGCTAGGATTACAGGCATGAGCCACTGCGCCCAGCCCTTATAAATTTTTGTATAGACATTCCTTTGGTTGGAAGAA
TATTTATAGGCAATACAGTCAAAGTTTCAAAATAGCATCACACAAAACATGTTTATAAATGAACAGGATGTAATGTACATAGATGACATT
AAGAAAATTTGTATGAAATAATTTAGTCATCATGAAATATTTAGTTGTCATATAAAAACCCACTGTTTGAGAATGATGCTACTCTGATCT
AATGAATGTGAACATGTAGATGTTTTGTGTGTATTTTTTTAAATGAAAACTCAAAATAAGACAAGTAATTTGTTGATAAATATTTTTAAA
GATAACTCAGCATGTTTGTAAAGCAGGATACATTTTACTAAAAGGTTCATTGGTTCCAATCACAGCTCATAGGTAGAGCAAAGAAAGGGT
GGATGGATTGAAAAGATTAGCCTCTGTCTCGGTGGCAGGTTCCCACCTCGCAAGCAATTGGAAACAAAACTTTTGGGGAGTTTTATTTTG
CATTAGGGTGTGTTTTATGTTAAGCAAAACATACTTTAGAAACAAATGAAAAAGGCAATTGAAAATCCCAGCTATTTCACCTAGATGGAA
TAGCCACCCTGAGCAGAACTTTGTGATGCTTCATTCTGTGGAATTTTGTGCTTGCTACTGTATAGTGCATGTGGTGTAGGTTACTCTAAC
TGGTTTTGTCGACGTAAACATTTAAAGTGTTATATTTTTTATAAAAATGTTTATTTTTAATGATATGAGAAAAATTTTGTTAGGCCACAA
AAACACTGCACTGTGAACATTTTAGAAAAGGTATGTCAGACTGGGATTAATGACAGCATGATTTTCAATGACTGTAAATTGCGATAAGGA
AATGTACTGATTGCCAATACACCCCACCCTCATTACATCATCAGGACTTGAAGCCAAGGGTTAACCCAGCAAGCTACAAAGAGGGTGTGT
CACACTGAAACTCAATAGTTGAGTTTGGCTGTTGTTGCAGGAAAATGATTATAACTAAAAGCTCTCTGATAGTGCAGAGACTTACCAGAA
GACACAAGGAATTGTACTGAAGAGCTATTACAATCCAAATATTGCCGTTTCATAAATGTAATAAGTAATACTAATTCACAGAGTATTGTA
AATGGTGGATGACAAAAGAAAATCTGCTCTGTGGAAAGAAAGAACTGTCTCTACCAGGGTCAAGAGCATGAACGCATCAATAGAAAGAAC
TCGGGGAAACATCCCATCAACAGGACTACACACTTGTATATACATTCTTGAGAACACTGCAATGTGAAAATCACGTTTGCTATTTATAAA
CTTGTCCTTAGATTAATGTGTCTGGACAGATTGTGGGAGTAAGTGATTCTTCTAAGAATTAGATACTTGTCACTGCCTATACCTGCAGCT

>8923_8923_2_BAIAP2L1-MET_BAIAP2L1_chr7_97939756_ENST00000005260_MET_chr7_116414934_ENST00000397752_length(amino acids)=760AA_BP=378
MPQVLTFSQRRRARALSGRRLRRRPTLQSPLVAPRPSRCPESGGHEAQPRPPALARPAAAAMSRGPEEVNRLTESTYRNVMEQFNPGLRN
LINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGSPVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATL
KRYQTEHKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEALLEEKRRFCFLVDKHCGFANHIHY
YHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEEIKTPASTPVSGTPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPLID
MFNNPATAAPNSQRVNNSTDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHF
NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIR
NETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF
TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYV

--------------------------------------------------------------
>8923_8923_3_BAIAP2L1-MET_BAIAP2L1_chr7_97939757_ENST00000005260_MET_chr7_116414935_ENST00000318493_length(transcript)=2534nt_BP=1171nt
CTCCTCTGCTCCTCGAAGAAGGCCAGGGCGGCGCTGCCGCAAGTTTTGACATTTTCGCAGCGGAGACGCGCGCGGGCACTCTCGGGCCGA
CGGCTGCGGCGGCGGCCGACCCTCCAGAGCCCCTTAGTCGCGCCCCGGCCCTCCCGCTGCCCGGAGTCCGGCGGCCACGAGGCCCAGCCG
CGTCCTCCCGCGCTTGCTCGCCCGGCGGCCGCAGCCATGTCCCGGGGGCCCGAGGAGGTGAACCGGCTCACGGAGAGCACCTACCGGAAT
GTTATGGAACAGTTCAATCCTGGGCTGCGAAATTTAATAAACCTGGGGAAAAATTATGAGAAAGCTGTAAACGCTATGATCCTGGCAGGA
AAAGCCTACTACGATGGAGTGGCCAAGATCGGTGAGATTGCCACTGGGTCCCCCGTGTCAACTGAACTGGGACATGTCCTCATAGAGATT
TCAAGTACCCACAAGAAACTCAACGAGAGTCTTGATGAAAATTTTAAAAAATTCCACAAAGAGATTATCCATGAGCTGGAGAAGAAGATA
GAACTTGACGTGAAATATATGAACGCAACTCTAAAAAGATACCAAACAGAACACAAGAATAAATTAGAGTCTTTGGAGAAATCCCAAGCT
GAGTTGAAGAAGATCAGAAGGAAAAGCCAAGGAAGCCGAAACGCACTCAAATATGAACACAAAGAAATTGAGTATGTGGAGACCGTTACT
TCTCGTCAGAGTGAAATCCAGAAATTCATTGCAGATGGTTGCAAAGAGGCTCTGCTTGAAGAGAAGAGGCGCTTCTGCTTTCTGGTTGAT
AAGCACTGTGGCTTTGCAAACCACATACATTATTATCACTTACAGTCTGCAGAACTACTGAATTCCAAGCTGCCTCGGTGGCAGGAGACC
TGTGTTGATGCCATCAAAGTGCCAGAGAAAATCATGAATATGATCGAAGAAATAAAGACCCCAGCCTCTACCCCCGTGTCTGGAACTCCT
CAGGCTTCACCCATGATCGAGAGAAGCAATGTGGTTAGGAAAGATTACGACACCCTTTCTAAATGCTCACCAAAGATGCCCCCCGCTCCT
TCAGGCAGAGCATATACCAGTCCCTTGATCGATATGTTTAATAACCCAGCCACGGCTGCCCCGAATTCACAAAGGGTAAATAATTCAACA
GATCAGTTTCCTAATTCATCTCAGAACGGTTCATGCCGACAAGTGCAGTATCCTCTGACAGACATGTCCCCCATCCTAACTAGTGGGGAC
TCTGATATATCCAGTCCATTACTGCAAAATACTGTCCACATTGACCTCAGTGCTCTAAATCCAGAGCTGGTCCAGGCAGTGCAGCATGTA
GTGATTGGGCCCAGTAGCCTGATTGTGCATTTCAATGAAGTCATAGGAAGAGGGCATTTTGGTTGTGTATATCATGGGACTTTGTTGGAC
AATGATGGCAAGAAAATTCACTGTGCTGTGAAATCCTTGAACAGAATCACTGACATAGGAGAAGTTTCCCAATTTCTGACCGAGGGAATC
ATCATGAAAGATTTTAGTCATCCCAATGTCCTCTCGCTCCTGGGAATCTGCCTGCGAAGTGAAGGGTCTCCGCTGGTGGTCCTACCATAC
ATGAAACATGGAGATCTTCGAAATTTCATTCGAAATGAGACTCATAATCCAACTGTAAAAGATCTTATTGGCTTTGGTCTTCAAGTAGCC
AAAGGCATGAAATATCTTGCAAGCAAAAAGTTTGTCCACAGAGACTTGGCTGCAAGAAACTGTATGCTGGATGAAAAATTCACAGTCAAG
GTTGCTGATTTTGGTCTTGCCAGAGACATGTATGATAAAGAATACTATAGTGTACACAACAAAACAGGTGCAAAGCTGCCAGTGAAGTGG
ATGGCTTTGGAAAGTCTGCAAACTCAAAAGTTTACCACCAAGTCAGATGTGTGGTCCTTTGGCGTGCTCCTCTGGGAGCTGATGACAAGA
GGAGCCCCACCTTATCCTGACGTAAACACCTTTGATATAACTGTTTACTTGTTGCAAGGGAGAAGACTCCTACAACCCGAATACTGCCCA
GACCCCTTATATGAAGTAATGCTAAAATGCTGGCACCCTAAAGCCGAAATGCGCCCATCCTTTTCTGAACTGGTGTCCCGGATATCAGCG
ATCTTCTCTACTTTCATTGGGGAGCACTATGTCCATGTGAACGCTACTTATGTGAACGTAAAATGTGTCGCTCCGTATCCTTCTCTGTTG
TCATCAGAAGATAACGCTGATGATGAGGTGGACACACGACCAGCCTCCTTCTGGGAGACATCATAGTGCTAGTACTATGTCAAAGCAACA
GTCCACACTTTGTCCAATGGTTTTTTCACTGCCTGACCTTTAAAAGGCCATCGATATTCTTTGCTCTTGCCAAAATTGCACTATTATAGG
ACTTGTATTGTTATTTAAATTACTGGATTCTAAGGAATTTCTTATCTGACAGAGCATCAGAACCAGAGGCTTGGTCCCACAGGCCACGGA

>8923_8923_3_BAIAP2L1-MET_BAIAP2L1_chr7_97939757_ENST00000005260_MET_chr7_116414935_ENST00000318493_length(amino acids)=760AA_BP=378
MPQVLTFSQRRRARALSGRRLRRRPTLQSPLVAPRPSRCPESGGHEAQPRPPALARPAAAAMSRGPEEVNRLTESTYRNVMEQFNPGLRN
LINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGSPVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATL
KRYQTEHKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEALLEEKRRFCFLVDKHCGFANHIHY
YHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEEIKTPASTPVSGTPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPLID
MFNNPATAAPNSQRVNNSTDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHF
NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIR
NETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF
TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYV

--------------------------------------------------------------
>8923_8923_4_BAIAP2L1-MET_BAIAP2L1_chr7_97939757_ENST00000005260_MET_chr7_116414935_ENST00000397752_length(transcript)=4578nt_BP=1171nt
CTCCTCTGCTCCTCGAAGAAGGCCAGGGCGGCGCTGCCGCAAGTTTTGACATTTTCGCAGCGGAGACGCGCGCGGGCACTCTCGGGCCGA
CGGCTGCGGCGGCGGCCGACCCTCCAGAGCCCCTTAGTCGCGCCCCGGCCCTCCCGCTGCCCGGAGTCCGGCGGCCACGAGGCCCAGCCG
CGTCCTCCCGCGCTTGCTCGCCCGGCGGCCGCAGCCATGTCCCGGGGGCCCGAGGAGGTGAACCGGCTCACGGAGAGCACCTACCGGAAT
GTTATGGAACAGTTCAATCCTGGGCTGCGAAATTTAATAAACCTGGGGAAAAATTATGAGAAAGCTGTAAACGCTATGATCCTGGCAGGA
AAAGCCTACTACGATGGAGTGGCCAAGATCGGTGAGATTGCCACTGGGTCCCCCGTGTCAACTGAACTGGGACATGTCCTCATAGAGATT
TCAAGTACCCACAAGAAACTCAACGAGAGTCTTGATGAAAATTTTAAAAAATTCCACAAAGAGATTATCCATGAGCTGGAGAAGAAGATA
GAACTTGACGTGAAATATATGAACGCAACTCTAAAAAGATACCAAACAGAACACAAGAATAAATTAGAGTCTTTGGAGAAATCCCAAGCT
GAGTTGAAGAAGATCAGAAGGAAAAGCCAAGGAAGCCGAAACGCACTCAAATATGAACACAAAGAAATTGAGTATGTGGAGACCGTTACT
TCTCGTCAGAGTGAAATCCAGAAATTCATTGCAGATGGTTGCAAAGAGGCTCTGCTTGAAGAGAAGAGGCGCTTCTGCTTTCTGGTTGAT
AAGCACTGTGGCTTTGCAAACCACATACATTATTATCACTTACAGTCTGCAGAACTACTGAATTCCAAGCTGCCTCGGTGGCAGGAGACC
TGTGTTGATGCCATCAAAGTGCCAGAGAAAATCATGAATATGATCGAAGAAATAAAGACCCCAGCCTCTACCCCCGTGTCTGGAACTCCT
CAGGCTTCACCCATGATCGAGAGAAGCAATGTGGTTAGGAAAGATTACGACACCCTTTCTAAATGCTCACCAAAGATGCCCCCCGCTCCT
TCAGGCAGAGCATATACCAGTCCCTTGATCGATATGTTTAATAACCCAGCCACGGCTGCCCCGAATTCACAAAGGGTAAATAATTCAACA
GATCAGTTTCCTAATTCATCTCAGAACGGTTCATGCCGACAAGTGCAGTATCCTCTGACAGACATGTCCCCCATCCTAACTAGTGGGGAC
TCTGATATATCCAGTCCATTACTGCAAAATACTGTCCACATTGACCTCAGTGCTCTAAATCCAGAGCTGGTCCAGGCAGTGCAGCATGTA
GTGATTGGGCCCAGTAGCCTGATTGTGCATTTCAATGAAGTCATAGGAAGAGGGCATTTTGGTTGTGTATATCATGGGACTTTGTTGGAC
AATGATGGCAAGAAAATTCACTGTGCTGTGAAATCCTTGAACAGAATCACTGACATAGGAGAAGTTTCCCAATTTCTGACCGAGGGAATC
ATCATGAAAGATTTTAGTCATCCCAATGTCCTCTCGCTCCTGGGAATCTGCCTGCGAAGTGAAGGGTCTCCGCTGGTGGTCCTACCATAC
ATGAAACATGGAGATCTTCGAAATTTCATTCGAAATGAGACTCATAATCCAACTGTAAAAGATCTTATTGGCTTTGGTCTTCAAGTAGCC
AAAGGCATGAAATATCTTGCAAGCAAAAAGTTTGTCCACAGAGACTTGGCTGCAAGAAACTGTATGCTGGATGAAAAATTCACAGTCAAG
GTTGCTGATTTTGGTCTTGCCAGAGACATGTATGATAAAGAATACTATAGTGTACACAACAAAACAGGTGCAAAGCTGCCAGTGAAGTGG
ATGGCTTTGGAAAGTCTGCAAACTCAAAAGTTTACCACCAAGTCAGATGTGTGGTCCTTTGGCGTGCTCCTCTGGGAGCTGATGACAAGA
GGAGCCCCACCTTATCCTGACGTAAACACCTTTGATATAACTGTTTACTTGTTGCAAGGGAGAAGACTCCTACAACCCGAATACTGCCCA
GACCCCTTATATGAAGTAATGCTAAAATGCTGGCACCCTAAAGCCGAAATGCGCCCATCCTTTTCTGAACTGGTGTCCCGGATATCAGCG
ATCTTCTCTACTTTCATTGGGGAGCACTATGTCCATGTGAACGCTACTTATGTGAACGTAAAATGTGTCGCTCCGTATCCTTCTCTGTTG
TCATCAGAAGATAACGCTGATGATGAGGTGGACACACGACCAGCCTCCTTCTGGGAGACATCATAGTGCTAGTACTATGTCAAAGCAACA
GTCCACACTTTGTCCAATGGTTTTTTCACTGCCTGACCTTTAAAAGGCCATCGATATTCTTTGCTCTTGCCAAAATTGCACTATTATAGG
ACTTGTATTGTTATTTAAATTACTGGATTCTAAGGAATTTCTTATCTGACAGAGCATCAGAACCAGAGGCTTGGTCCCACAGGCCACGGA
CCAATGGCCTGCAGCCGTGACAACACTCCTGTCATATTGGAGTCCAAAACTTGAATTCTGGGTTGAATTTTTTAAAAATCAGGTACCACT
TGATTTCATATGGGAAATTGAAGCAGGAAATATTGAGGGCTTCTTGATCACAGAAAACTCAGAAGAGATAGTAATGCTCAGGACAGGAGC
GGCAGCCCCAGAACAGGCCACTCATTTAGAATTCTAGTGTTTCAAAACACTTTTGTGTGTTGTATGGTCAATAACATTTTTCATTACTGA
TGGTGTCATTCACCCATTAGGTAAACATTCCCTTTTAAATGTTTGTTTGTTTTTTGAGACAGGATCTCACTCTGTTGCCAGGGCTGTAGT
GCAGTGGTGTGATCATAGCTCACTGCAACCTCCACCTCCCAGGCTCAAGCCTCCCGAATAGCTGGGACTACAGGCGCACACCACCATCCC
CGGCTAATTTTTGTATTTTTTGTAGAGACGGGGTTTTGCCATGTTGCCAAGGCTGGTTTCAAACTCCTGGACTCAAGAAATCCACCCACC
TCAGCCTCCCAAAGTGCTAGGATTACAGGCATGAGCCACTGCGCCCAGCCCTTATAAATTTTTGTATAGACATTCCTTTGGTTGGAAGAA
TATTTATAGGCAATACAGTCAAAGTTTCAAAATAGCATCACACAAAACATGTTTATAAATGAACAGGATGTAATGTACATAGATGACATT
AAGAAAATTTGTATGAAATAATTTAGTCATCATGAAATATTTAGTTGTCATATAAAAACCCACTGTTTGAGAATGATGCTACTCTGATCT
AATGAATGTGAACATGTAGATGTTTTGTGTGTATTTTTTTAAATGAAAACTCAAAATAAGACAAGTAATTTGTTGATAAATATTTTTAAA
GATAACTCAGCATGTTTGTAAAGCAGGATACATTTTACTAAAAGGTTCATTGGTTCCAATCACAGCTCATAGGTAGAGCAAAGAAAGGGT
GGATGGATTGAAAAGATTAGCCTCTGTCTCGGTGGCAGGTTCCCACCTCGCAAGCAATTGGAAACAAAACTTTTGGGGAGTTTTATTTTG
CATTAGGGTGTGTTTTATGTTAAGCAAAACATACTTTAGAAACAAATGAAAAAGGCAATTGAAAATCCCAGCTATTTCACCTAGATGGAA
TAGCCACCCTGAGCAGAACTTTGTGATGCTTCATTCTGTGGAATTTTGTGCTTGCTACTGTATAGTGCATGTGGTGTAGGTTACTCTAAC
TGGTTTTGTCGACGTAAACATTTAAAGTGTTATATTTTTTATAAAAATGTTTATTTTTAATGATATGAGAAAAATTTTGTTAGGCCACAA
AAACACTGCACTGTGAACATTTTAGAAAAGGTATGTCAGACTGGGATTAATGACAGCATGATTTTCAATGACTGTAAATTGCGATAAGGA
AATGTACTGATTGCCAATACACCCCACCCTCATTACATCATCAGGACTTGAAGCCAAGGGTTAACCCAGCAAGCTACAAAGAGGGTGTGT
CACACTGAAACTCAATAGTTGAGTTTGGCTGTTGTTGCAGGAAAATGATTATAACTAAAAGCTCTCTGATAGTGCAGAGACTTACCAGAA
GACACAAGGAATTGTACTGAAGAGCTATTACAATCCAAATATTGCCGTTTCATAAATGTAATAAGTAATACTAATTCACAGAGTATTGTA
AATGGTGGATGACAAAAGAAAATCTGCTCTGTGGAAAGAAAGAACTGTCTCTACCAGGGTCAAGAGCATGAACGCATCAATAGAAAGAAC
TCGGGGAAACATCCCATCAACAGGACTACACACTTGTATATACATTCTTGAGAACACTGCAATGTGAAAATCACGTTTGCTATTTATAAA
CTTGTCCTTAGATTAATGTGTCTGGACAGATTGTGGGAGTAAGTGATTCTTCTAAGAATTAGATACTTGTCACTGCCTATACCTGCAGCT

>8923_8923_4_BAIAP2L1-MET_BAIAP2L1_chr7_97939757_ENST00000005260_MET_chr7_116414935_ENST00000397752_length(amino acids)=760AA_BP=378
MPQVLTFSQRRRARALSGRRLRRRPTLQSPLVAPRPSRCPESGGHEAQPRPPALARPAAAAMSRGPEEVNRLTESTYRNVMEQFNPGLRN
LINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGSPVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATL
KRYQTEHKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEALLEEKRRFCFLVDKHCGFANHIHY
YHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEEIKTPASTPVSGTPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPLID
MFNNPATAAPNSQRVNNSTDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHF
NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIR
NETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF
TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for BAIAP2L1-MET


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneMETchr7:97939756chr7:116414934ENST0000031849313211320_13591027.33333333333331409.0MUC20
TgeneMETchr7:97939756chr7:116414934ENST0000039775213211320_13591009.33333333333341391.0MUC20
TgeneMETchr7:97939756chr7:116414934ENST00000436117091320_13590.0765.0MUC20
TgeneMETchr7:97939757chr7:116414935ENST0000031849313211320_13591027.33333333333331409.0MUC20
TgeneMETchr7:97939757chr7:116414935ENST0000039775213211320_13591009.33333333333341391.0MUC20
TgeneMETchr7:97939757chr7:116414935ENST00000436117091320_13590.0765.0MUC20
TgeneMETchr7:97939756chr7:116414934ENST0000031849313211212_13901027.33333333333331409.0RANBP9
TgeneMETchr7:97939756chr7:116414934ENST0000039775213211212_13901009.33333333333341391.0RANBP9
TgeneMETchr7:97939756chr7:116414934ENST00000436117091212_13900.0765.0RANBP9
TgeneMETchr7:97939757chr7:116414935ENST0000031849313211212_13901027.33333333333331409.0RANBP9
TgeneMETchr7:97939757chr7:116414935ENST0000039775213211212_13901009.33333333333341391.0RANBP9
TgeneMETchr7:97939757chr7:116414935ENST00000436117091212_13900.0765.0RANBP9


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BAIAP2L1-MET


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BAIAP2L1-MET


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource