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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TBC1D22A-ARFGAP3 (FusionGDB2 ID:89283)

Fusion Gene Summary for TBC1D22A-ARFGAP3

check button Fusion gene summary
Fusion gene informationFusion gene name: TBC1D22A-ARFGAP3
Fusion gene ID: 89283
HgeneTgene
Gene symbol

TBC1D22A

ARFGAP3

Gene ID

25771

26286

Gene nameTBC1 domain family member 22AADP ribosylation factor GTPase activating protein 3
SynonymsC22orf4|HSC79E021ARFGAP1
Cytomap

22q13.31

22q13.2

Type of geneprotein-codingprotein-coding
DescriptionTBC1 domain family member 22Aputative GTPase activatorADP-ribosylation factor GTPase-activating protein 3ADP-ribosylation factor GTPase activating protein 1ARF GAP 3
Modification date2020031320200313
UniProtAcc.

Q9NP61

Ensembl transtripts involved in fusion geneENST00000380995, ENST00000337137, 
ENST00000355704, ENST00000407381, 
ENST00000406733, ENST00000472791, 
ENST00000263245, ENST00000429508, 
ENST00000437119, 
Fusion gene scores* DoF score34 X 18 X 14=85689 X 9 X 5=405
# samples 3715
** MAII scorelog2(37/8568*10)=-4.53336130423394
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/405*10)=-1.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TBC1D22A [Title/Abstract] AND ARFGAP3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTBC1D22A(47158745)-ARFGAP3(43195166), # samples:3
Anticipated loss of major functional domain due to fusion event.TBC1D22A-ARFGAP3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across TBC1D22A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ARFGAP3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-EE-A2ME-06ATBC1D22Achr22

47158745

-ARFGAP3chr22

43195166

-
ChimerDB4SKCMTCGA-EE-A2ME-06ATBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
ChimerDB4SKCMTCGA-FS-A4F4-06ATBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-


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Fusion Gene ORF analysis for TBC1D22A-ARFGAP3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000380995ENST00000263245TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
5UTR-3CDSENST00000380995ENST00000429508TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
5UTR-3CDSENST00000380995ENST00000437119TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
Frame-shiftENST00000337137ENST00000263245TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
Frame-shiftENST00000337137ENST00000429508TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
Frame-shiftENST00000337137ENST00000437119TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
Frame-shiftENST00000355704ENST00000263245TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
Frame-shiftENST00000355704ENST00000429508TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
Frame-shiftENST00000355704ENST00000437119TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
Frame-shiftENST00000407381ENST00000263245TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
Frame-shiftENST00000407381ENST00000429508TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
Frame-shiftENST00000407381ENST00000437119TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
In-frameENST00000337137ENST00000263245TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
In-frameENST00000337137ENST00000429508TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
In-frameENST00000337137ENST00000437119TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
In-frameENST00000355704ENST00000263245TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
In-frameENST00000355704ENST00000429508TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
In-frameENST00000355704ENST00000437119TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
In-frameENST00000380995ENST00000263245TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
In-frameENST00000380995ENST00000429508TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
In-frameENST00000380995ENST00000437119TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
In-frameENST00000406733ENST00000263245TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
In-frameENST00000406733ENST00000429508TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
In-frameENST00000406733ENST00000437119TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
In-frameENST00000407381ENST00000263245TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
In-frameENST00000407381ENST00000429508TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
In-frameENST00000407381ENST00000437119TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
intron-3CDSENST00000406733ENST00000263245TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
intron-3CDSENST00000406733ENST00000429508TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
intron-3CDSENST00000406733ENST00000437119TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
intron-3CDSENST00000472791ENST00000263245TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
intron-3CDSENST00000472791ENST00000263245TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
intron-3CDSENST00000472791ENST00000429508TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
intron-3CDSENST00000472791ENST00000429508TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-
intron-3CDSENST00000472791ENST00000437119TBC1D22Achr22

47158745

+ARFGAP3chr22

43195166

-
intron-3CDSENST00000472791ENST00000437119TBC1D22Achr22

47189738

+ARFGAP3chr22

43219708

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000337137TBC1D22Achr2247189738+ENST00000263245ARFGAP3chr2243219708-26386261661551461
ENST00000337137TBC1D22Achr2247189738+ENST00000429508ARFGAP3chr2243219708-17716261661551461
ENST00000337137TBC1D22Achr2247189738+ENST00000437119ARFGAP3chr2243219708-17266261661551461
ENST00000380995TBC1D22Achr2247189738+ENST00000263245ARFGAP3chr2243219708-26276151551540461
ENST00000380995TBC1D22Achr2247189738+ENST00000429508ARFGAP3chr2243219708-17606151551540461
ENST00000380995TBC1D22Achr2247189738+ENST00000437119ARFGAP3chr2243219708-17156151551540461
ENST00000407381TBC1D22Achr2247189738+ENST00000263245ARFGAP3chr2243219708-25875751151500461
ENST00000407381TBC1D22Achr2247189738+ENST00000429508ARFGAP3chr2243219708-17205751151500461
ENST00000407381TBC1D22Achr2247189738+ENST00000437119ARFGAP3chr2243219708-16755751151500461
ENST00000355704TBC1D22Achr2247189738+ENST00000263245ARFGAP3chr2243219708-25215091061434442
ENST00000355704TBC1D22Achr2247189738+ENST00000429508ARFGAP3chr2243219708-16545091061434442
ENST00000355704TBC1D22Achr2247189738+ENST00000437119ARFGAP3chr2243219708-16095091061434442
ENST00000406733TBC1D22Achr2247189738+ENST00000263245ARFGAP3chr2243219708-27197072411632463
ENST00000406733TBC1D22Achr2247189738+ENST00000429508ARFGAP3chr2243219708-18527072411632463
ENST00000406733TBC1D22Achr2247189738+ENST00000437119ARFGAP3chr2243219708-18077072411632463

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000337137ENST00000263245TBC1D22Achr2247189738+ARFGAP3chr2243219708-0.0004939410.999506
ENST00000337137ENST00000429508TBC1D22Achr2247189738+ARFGAP3chr2243219708-0.0022184190.9977816
ENST00000337137ENST00000437119TBC1D22Achr2247189738+ARFGAP3chr2243219708-0.0024910320.997509
ENST00000380995ENST00000263245TBC1D22Achr2247189738+ARFGAP3chr2243219708-0.0004881260.99951184
ENST00000380995ENST00000429508TBC1D22Achr2247189738+ARFGAP3chr2243219708-0.002035410.9979646
ENST00000380995ENST00000437119TBC1D22Achr2247189738+ARFGAP3chr2243219708-0.0023022120.9976978
ENST00000407381ENST00000263245TBC1D22Achr2247189738+ARFGAP3chr2243219708-0.0004428040.9995572
ENST00000407381ENST00000429508TBC1D22Achr2247189738+ARFGAP3chr2243219708-0.0017088990.9982911
ENST00000407381ENST00000437119TBC1D22Achr2247189738+ARFGAP3chr2243219708-0.0019750740.99802494
ENST00000355704ENST00000263245TBC1D22Achr2247189738+ARFGAP3chr2243219708-0.0006486910.9993513
ENST00000355704ENST00000429508TBC1D22Achr2247189738+ARFGAP3chr2243219708-0.0019624860.9980375
ENST00000355704ENST00000437119TBC1D22Achr2247189738+ARFGAP3chr2243219708-0.0022068920.9977931
ENST00000406733ENST00000263245TBC1D22Achr2247189738+ARFGAP3chr2243219708-0.001348040.99865204
ENST00000406733ENST00000429508TBC1D22Achr2247189738+ARFGAP3chr2243219708-0.0030498370.9969502
ENST00000406733ENST00000437119TBC1D22Achr2247189738+ARFGAP3chr2243219708-0.0033544670.9966455

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Fusion Genomic Features for TBC1D22A-ARFGAP3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TBC1D22A-ARFGAP3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:47158745/chr22:43195166)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ARFGAP3

Q9NP61

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. {ECO:0000269|PubMed:11172815}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneARFGAP3chr22:47189738chr22:43219708ENST00000263245616243_263208517.0Coiled coilOntology_term=ECO:0000255
TgeneARFGAP3chr22:47189738chr22:43219708ENST00000437119515243_263164473.0Coiled coilOntology_term=ECO:0000255
TgeneARFGAP3chr22:47189738chr22:43219708ENST00000263245616348_377208517.0Compositional biasNote=Ser-rich
TgeneARFGAP3chr22:47189738chr22:43219708ENST00000437119515348_377164473.0Compositional biasNote=Ser-rich

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTBC1D22Achr22:47189738chr22:43219708ENST00000337137+313222_446153518.0DomainRab-GAP TBC
HgeneTBC1D22Achr22:47189738chr22:43219708ENST00000355704+211222_446134440.0DomainRab-GAP TBC
HgeneTBC1D22Achr22:47189738chr22:43219708ENST00000380995+39222_446106325.0DomainRab-GAP TBC
TgeneARFGAP3chr22:47189738chr22:43219708ENST0000026324561610_126208517.0DomainArf-GAP
TgeneARFGAP3chr22:47189738chr22:43219708ENST0000043711951510_126164473.0DomainArf-GAP
TgeneARFGAP3chr22:47189738chr22:43219708ENST0000026324561625_48208517.0Zinc fingerC4-type
TgeneARFGAP3chr22:47189738chr22:43219708ENST0000043711951525_48164473.0Zinc fingerC4-type


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Fusion Gene Sequence for TBC1D22A-ARFGAP3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>89283_89283_1_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000337137_ARFGAP3_chr22_43219708_ENST00000263245_length(transcript)=2638nt_BP=626nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGT
ATCCTCTATCATAAAAAAGAAACCAAATCAAGCTAAAAAAGGCCTTGGGGCCAAAAAAGGAAGTTTGGGAGCTCAGAAACTGGCAAACAC
ATGCTTTAATGAAATTGAAAAACAAGCTCAAGCTGCGGATAAAATGAAGGAGCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATC
AATTGTTTCATCATTACGATTAGCCTATAAGGATCTTGAAATTCAAATGAAGAAAGACGAAAAGATGAACATTAGTGGCAAAAAAAATGT
TGACTCAGACAGACTCGGCATGGGATTTGGAAATTGCAGAAGTGTTATTTCACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGA
ATCACCCATTATGGCAAAACCAAGAAAAAAGTATAATGATGACAGTGACGATTCATATTTTACTTCCAGCTCAAGTTACTTTGACGAGCC
AGTGGAGTTAAGGAGCAGTTCTTTCTCTAGCTGGGATGACAGTTCAGATTCCTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGT
TCTGAAAACCACAGGCTATTCAGACAGACCTACTGCTCGCCGCAAGCCAGATTATGAGCCAGTTGAAAATACAGATGAGGCCCAGAAGAA
GTTTGGCAATGTCAAGGCCATTTCATCAGATATGTATTTTGGAAGACAATCCCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCT
GTCGGCAAGTTCCTCCATAAGCTCGGCTGATCTGTTCGAGGAGCCGAGGAAGCAGCCAGCAGGGAACTACAGCCTGTCCAGTGTGCTGCC
CAACGCCCCCGACATGGCGCAGTTCAAGCAGGGAGTGAGATCGGTTGCTGGAAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAAT
TCAGGATCGCTACGGTTCTTAATACTGAAGTCATGATGTGTATTTCCTGGAGAAATTCCTCTTTAAATGAACAAGTAACCACATCTCAGG
CGGCAGTGAAGTCCAGATAGTTTTGCAGATTGTTTTGCTACTTTTTCATATGGTATATGTTTCTGATTTTTAATATTTCTTTTGAGAAAT
TCTGAGTTCTGATGTAGGAGCTTTCCTGTGATTTCTGTTTCACGTTCCTTCCTGTCACACCCTCCTTTGGCGTCTCTGTGTATATCCTTG
CTTTATTTTCTTGGAACCTTTGATTTCAACACTGAGGGCCTGGAGACCTCGGCTCCTCCTGCTCCTGAACCAGGAGGCTTCATGTGGGGG
AGGAGGAGAGGTCTCCATGTGACACATGGGCTCAGGGCTGCCAGAATCAGCGGATGCTGGATGGGCCTGCAGAAACAACACTCACCACAC
ACACTTCCTTCAAAAGACCAAAAGTGACTGGTGTCTCGTGTGACAGATTGCTTCATTTATGTTTCTACATAGTAAGGTGACTGCCAAATA
ATATTTGAAGTCATCTGTCTCTTTGTAAATTATTTTATATGACCTATAAATTTAAAAATGTTTTTCAGTGAGTGCTTTTAACAAACTTAA
GCTTCTGCCCTGCCAAGGGAATTAATGTTATCTTGTGAAAGGTGTTGCTGTTTGAATTGATGAGAAATGGAAGATGAGAACTCCCTAAGA
GTTCTCATAATAAATCATCTCATCACAAATCAATACGGTATACAGAGTTAAAGTGGAATGAGGTAAGAAGATACAGCTACAGAAAATAGT
TGCGTGTATGGGAGAACAGTCATTGTAATTGGGTAGTTTTGTTAATAAATATTTTTAAATCTTGCTTTTCAGAAATTACCGAATGTGTAT
AAACAAATAAAGAAAAATAATTTAGCTGTGTTTTAGACAGCATTAGAATATATTGTTCAGCACAGTAAAATATATTTGAAATTTGATAAG
CCAAAAATGTGGTTTTGAATGAATATTTTGTGAATCTTTCTTAAAAGCTCAAATTTGTAGACTTCTAAATAGAATAAACACTTGCAGCAG

>89283_89283_1_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000337137_ARFGAP3_chr22_43219708_ENST00000263245_length(amino acids)=461AA_BP=152
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEVSSIIKKKPNQAKKGLGAKKGSLGAQ
KLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQ
TIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTD
EAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANG

--------------------------------------------------------------
>89283_89283_2_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000337137_ARFGAP3_chr22_43219708_ENST00000429508_length(transcript)=1771nt_BP=626nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGT
ATCCTCTATCATAAAAAAGAAACCAAATCAAGCTAAAAAAGGCCTTGGGGCCAAAAAAGGAAGTTTGGGAGCTCAGAAACTGGCAAACAC
ATGCTTTAATGAAATTGAAAAACAAGCTCAAGCTGCGGATAAAATGAAGGAGCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATC
AATTGTTTCATCATTACGATTAGCCTATAAGGATCTTGAAATTCAAATGAAGAAAGACGAAAAGATGAACATTAGTGGCAAAAAAAATGT
TGACTCAGACAGACTCGGCATGGGATTTGGAAATTGCAGAAGTGTTATTTCACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGA
ATCACCCATTATGGCAAAACCAAGAAAAAAGTATAATGATGACAGTGACGATTCATATTTTACTTCCAGCTCAAGTTACTTTGACGAGCC
AGTGGAGTTAAGGAGCAGTTCTTTCTCTAGCTGGGATGACAGTTCAGATTCCTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGT
TCTGAAAACCACAGGCTATTCAGACAGACCTACTGCTCGCCGCAAGCCAGATTATGAGCCAGTTGAAAATACAGATGAGGCCCAGAAGAA
GTTTGGCAATGTCAAGGCCATTTCATCAGATATGTATTTTGGAAGACAATCCCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCT
GTCGGCAAGTTCCTCCATAAGCTCGGCTGATCTGTTCGAGGAGCCGAGGAAGCAGCCAGCAGGGAACTACAGCCTGTCCAGTGTGCTGCC
CAACGCCCCCGACATGGCGCAGTTCAAGCAGGGAGTGAGATCGGTTGCTGGAAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAAT
TCAGGATCGCTACGGTTCTTAATACTGAAGTCATGATGTGTATTTCCTGGAGAAATTCCTCTTTAAATGAACAAGTAACCACATCTCAGG
CGGCAGTGAAGTCCAGATAGTTTTGCAGATTGTTTTGCTACTTTTTCATATGGTATATGTTTCTGATTTTTAATATTTCTTTTGAGAAAT

>89283_89283_2_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000337137_ARFGAP3_chr22_43219708_ENST00000429508_length(amino acids)=461AA_BP=152
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEVSSIIKKKPNQAKKGLGAKKGSLGAQ
KLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQ
TIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTD
EAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANG

--------------------------------------------------------------
>89283_89283_3_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000337137_ARFGAP3_chr22_43219708_ENST00000437119_length(transcript)=1726nt_BP=626nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGT
ATCCTCTATCATAAAAAAGAAACCAAATCAAGCTAAAAAAGGCCTTGGGGCCAAAAAAGGAAGTTTGGGAGCTCAGAAACTGGCAAACAC
ATGCTTTAATGAAATTGAAAAACAAGCTCAAGCTGCGGATAAAATGAAGGAGCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATC
AATTGTTTCATCATTACGATTAGCCTATAAGGATCTTGAAATTCAAATGAAGAAAGACGAAAAGATGAACATTAGTGGCAAAAAAAATGT
TGACTCAGACAGACTCGGCATGGGATTTGGAAATTGCAGAAGTGTTATTTCACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGA
ATCACCCATTATGGCAAAACCAAGAAAAAAGTATAATGATGACAGTGACGATTCATATTTTACTTCCAGCTCAAGTTACTTTGACGAGCC
AGTGGAGTTAAGGAGCAGTTCTTTCTCTAGCTGGGATGACAGTTCAGATTCCTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGT
TCTGAAAACCACAGGCTATTCAGACAGACCTACTGCTCGCCGCAAGCCAGATTATGAGCCAGTTGAAAATACAGATGAGGCCCAGAAGAA
GTTTGGCAATGTCAAGGCCATTTCATCAGATATGTATTTTGGAAGACAATCCCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCT
GTCGGCAAGTTCCTCCATAAGCTCGGCTGATCTGTTCGAGGAGCCGAGGAAGCAGCCAGCAGGGAACTACAGCCTGTCCAGTGTGCTGCC
CAACGCCCCCGACATGGCGCAGTTCAAGCAGGGAGTGAGATCGGTTGCTGGAAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAAT
TCAGGATCGCTACGGTTCTTAATACTGAAGTCATGATGTGTATTTCCTGGAGAAATTCCTCTTTAAATGAACAAGTAACCACATCTCAGG
CGGCAGTGAAGTCCAGATAGTTTTGCAGATTGTTTTGCTACTTTTTCATATGGTATATGTTTCTGATTTTTAATATTTCTTTTGAGAAAT

>89283_89283_3_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000337137_ARFGAP3_chr22_43219708_ENST00000437119_length(amino acids)=461AA_BP=152
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEVSSIIKKKPNQAKKGLGAKKGSLGAQ
KLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQ
TIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTD
EAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANG

--------------------------------------------------------------
>89283_89283_4_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000355704_ARFGAP3_chr22_43219708_ENST00000263245_length(transcript)=2521nt_BP=509nt
CCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGA
GGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGTTTGCTCAGGTC
CACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCAGCGATGCCTGGGACGC
TGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCAACCGTGTGCTGCGTAA
CCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAGAGCCGCCCTCACCCCC
CAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGTATCCTCTATCATAAAAAAGAAACCAAA
TCAAGCTAAAAAAGGCCTTGGGGCCAAAAAAGGAAGTTTGGGAGCTCAGAAACTGGCAAACACATGCTTTAATGAAATTGAAAAACAAGC
TCAAGCTGCGGATAAAATGAAGGAGCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATCAATTGTTTCATCATTACGATTAGCCTA
TAAGGATCTTGAAATTCAAATGAAGAAAGACGAAAAGATGAACATTAGTGGCAAAAAAAATGTTGACTCAGACAGACTCGGCATGGGATT
TGGAAATTGCAGAAGTGTTATTTCACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGAATCACCCATTATGGCAAAACCAAGAAA
AAAGTATAATGATGACAGTGACGATTCATATTTTACTTCCAGCTCAAGTTACTTTGACGAGCCAGTGGAGTTAAGGAGCAGTTCTTTCTC
TAGCTGGGATGACAGTTCAGATTCCTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGTTCTGAAAACCACAGGCTATTCAGACAG
ACCTACTGCTCGCCGCAAGCCAGATTATGAGCCAGTTGAAAATACAGATGAGGCCCAGAAGAAGTTTGGCAATGTCAAGGCCATTTCATC
AGATATGTATTTTGGAAGACAATCCCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCTGTCGGCAAGTTCCTCCATAAGCTCGGC
TGATCTGTTCGAGGAGCCGAGGAAGCAGCCAGCAGGGAACTACAGCCTGTCCAGTGTGCTGCCCAACGCCCCCGACATGGCGCAGTTCAA
GCAGGGAGTGAGATCGGTTGCTGGAAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAATTCAGGATCGCTACGGTTCTTAATACTG
AAGTCATGATGTGTATTTCCTGGAGAAATTCCTCTTTAAATGAACAAGTAACCACATCTCAGGCGGCAGTGAAGTCCAGATAGTTTTGCA
GATTGTTTTGCTACTTTTTCATATGGTATATGTTTCTGATTTTTAATATTTCTTTTGAGAAATTCTGAGTTCTGATGTAGGAGCTTTCCT
GTGATTTCTGTTTCACGTTCCTTCCTGTCACACCCTCCTTTGGCGTCTCTGTGTATATCCTTGCTTTATTTTCTTGGAACCTTTGATTTC
AACACTGAGGGCCTGGAGACCTCGGCTCCTCCTGCTCCTGAACCAGGAGGCTTCATGTGGGGGAGGAGGAGAGGTCTCCATGTGACACAT
GGGCTCAGGGCTGCCAGAATCAGCGGATGCTGGATGGGCCTGCAGAAACAACACTCACCACACACACTTCCTTCAAAAGACCAAAAGTGA
CTGGTGTCTCGTGTGACAGATTGCTTCATTTATGTTTCTACATAGTAAGGTGACTGCCAAATAATATTTGAAGTCATCTGTCTCTTTGTA
AATTATTTTATATGACCTATAAATTTAAAAATGTTTTTCAGTGAGTGCTTTTAACAAACTTAAGCTTCTGCCCTGCCAAGGGAATTAATG
TTATCTTGTGAAAGGTGTTGCTGTTTGAATTGATGAGAAATGGAAGATGAGAACTCCCTAAGAGTTCTCATAATAAATCATCTCATCACA
AATCAATACGGTATACAGAGTTAAAGTGGAATGAGGTAAGAAGATACAGCTACAGAAAATAGTTGCGTGTATGGGAGAACAGTCATTGTA
ATTGGGTAGTTTTGTTAATAAATATTTTTAAATCTTGCTTTTCAGAAATTACCGAATGTGTATAAACAAATAAAGAAAAATAATTTAGCT
GTGTTTTAGACAGCATTAGAATATATTGTTCAGCACAGTAAAATATATTTGAAATTTGATAAGCCAAAAATGTGGTTTTGAATGAATATT
TTGTGAATCTTTCTTAAAAGCTCAAATTTGTAGACTTCTAAATAGAATAAACACTTGCAGCAGATGGCATTGCCTACATTTTTCCCTGAA

>89283_89283_4_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000355704_ARFGAP3_chr22_43219708_ENST00000263245_length(amino acids)=442AA_BP=133
MASDGARKQFWKRSNSKLPGSLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLNSEVVMETANRVLRNHSQRQ
GRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEVSSIIKKKPNQAKKGLGAKKGSLGAQKLANTCFNEIEKQAQAADK
MKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDD
SDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTDEAQKKFGNVKAISSDMYFG

--------------------------------------------------------------
>89283_89283_5_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000355704_ARFGAP3_chr22_43219708_ENST00000429508_length(transcript)=1654nt_BP=509nt
CCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGA
GGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGTTTGCTCAGGTC
CACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCAGCGATGCCTGGGACGC
TGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCAACCGTGTGCTGCGTAA
CCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAGAGCCGCCCTCACCCCC
CAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGTATCCTCTATCATAAAAAAGAAACCAAA
TCAAGCTAAAAAAGGCCTTGGGGCCAAAAAAGGAAGTTTGGGAGCTCAGAAACTGGCAAACACATGCTTTAATGAAATTGAAAAACAAGC
TCAAGCTGCGGATAAAATGAAGGAGCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATCAATTGTTTCATCATTACGATTAGCCTA
TAAGGATCTTGAAATTCAAATGAAGAAAGACGAAAAGATGAACATTAGTGGCAAAAAAAATGTTGACTCAGACAGACTCGGCATGGGATT
TGGAAATTGCAGAAGTGTTATTTCACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGAATCACCCATTATGGCAAAACCAAGAAA
AAAGTATAATGATGACAGTGACGATTCATATTTTACTTCCAGCTCAAGTTACTTTGACGAGCCAGTGGAGTTAAGGAGCAGTTCTTTCTC
TAGCTGGGATGACAGTTCAGATTCCTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGTTCTGAAAACCACAGGCTATTCAGACAG
ACCTACTGCTCGCCGCAAGCCAGATTATGAGCCAGTTGAAAATACAGATGAGGCCCAGAAGAAGTTTGGCAATGTCAAGGCCATTTCATC
AGATATGTATTTTGGAAGACAATCCCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCTGTCGGCAAGTTCCTCCATAAGCTCGGC
TGATCTGTTCGAGGAGCCGAGGAAGCAGCCAGCAGGGAACTACAGCCTGTCCAGTGTGCTGCCCAACGCCCCCGACATGGCGCAGTTCAA
GCAGGGAGTGAGATCGGTTGCTGGAAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAATTCAGGATCGCTACGGTTCTTAATACTG
AAGTCATGATGTGTATTTCCTGGAGAAATTCCTCTTTAAATGAACAAGTAACCACATCTCAGGCGGCAGTGAAGTCCAGATAGTTTTGCA
GATTGTTTTGCTACTTTTTCATATGGTATATGTTTCTGATTTTTAATATTTCTTTTGAGAAATTCTGAGTTCTGATGTAGGAGCTTTCCT

>89283_89283_5_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000355704_ARFGAP3_chr22_43219708_ENST00000429508_length(amino acids)=442AA_BP=133
MASDGARKQFWKRSNSKLPGSLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLNSEVVMETANRVLRNHSQRQ
GRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEVSSIIKKKPNQAKKGLGAKKGSLGAQKLANTCFNEIEKQAQAADK
MKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDD
SDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTDEAQKKFGNVKAISSDMYFG

--------------------------------------------------------------
>89283_89283_6_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000355704_ARFGAP3_chr22_43219708_ENST00000437119_length(transcript)=1609nt_BP=509nt
CCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGA
GGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGTTTGCTCAGGTC
CACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCAGCGATGCCTGGGACGC
TGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCAACCGTGTGCTGCGTAA
CCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAGAGCCGCCCTCACCCCC
CAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGTATCCTCTATCATAAAAAAGAAACCAAA
TCAAGCTAAAAAAGGCCTTGGGGCCAAAAAAGGAAGTTTGGGAGCTCAGAAACTGGCAAACACATGCTTTAATGAAATTGAAAAACAAGC
TCAAGCTGCGGATAAAATGAAGGAGCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATCAATTGTTTCATCATTACGATTAGCCTA
TAAGGATCTTGAAATTCAAATGAAGAAAGACGAAAAGATGAACATTAGTGGCAAAAAAAATGTTGACTCAGACAGACTCGGCATGGGATT
TGGAAATTGCAGAAGTGTTATTTCACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGAATCACCCATTATGGCAAAACCAAGAAA
AAAGTATAATGATGACAGTGACGATTCATATTTTACTTCCAGCTCAAGTTACTTTGACGAGCCAGTGGAGTTAAGGAGCAGTTCTTTCTC
TAGCTGGGATGACAGTTCAGATTCCTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGTTCTGAAAACCACAGGCTATTCAGACAG
ACCTACTGCTCGCCGCAAGCCAGATTATGAGCCAGTTGAAAATACAGATGAGGCCCAGAAGAAGTTTGGCAATGTCAAGGCCATTTCATC
AGATATGTATTTTGGAAGACAATCCCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCTGTCGGCAAGTTCCTCCATAAGCTCGGC
TGATCTGTTCGAGGAGCCGAGGAAGCAGCCAGCAGGGAACTACAGCCTGTCCAGTGTGCTGCCCAACGCCCCCGACATGGCGCAGTTCAA
GCAGGGAGTGAGATCGGTTGCTGGAAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAATTCAGGATCGCTACGGTTCTTAATACTG
AAGTCATGATGTGTATTTCCTGGAGAAATTCCTCTTTAAATGAACAAGTAACCACATCTCAGGCGGCAGTGAAGTCCAGATAGTTTTGCA

>89283_89283_6_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000355704_ARFGAP3_chr22_43219708_ENST00000437119_length(amino acids)=442AA_BP=133
MASDGARKQFWKRSNSKLPGSLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLNSEVVMETANRVLRNHSQRQ
GRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEVSSIIKKKPNQAKKGLGAKKGSLGAQKLANTCFNEIEKQAQAADK
MKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDD
SDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTDEAQKKFGNVKAISSDMYFG

--------------------------------------------------------------
>89283_89283_7_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000380995_ARFGAP3_chr22_43219708_ENST00000263245_length(transcript)=2627nt_BP=615nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGTATCCTCTATCA
TAAAAAAGAAACCAAATCAAGCTAAAAAAGGCCTTGGGGCCAAAAAAGGAAGTTTGGGAGCTCAGAAACTGGCAAACACATGCTTTAATG
AAATTGAAAAACAAGCTCAAGCTGCGGATAAAATGAAGGAGCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATCAATTGTTTCAT
CATTACGATTAGCCTATAAGGATCTTGAAATTCAAATGAAGAAAGACGAAAAGATGAACATTAGTGGCAAAAAAAATGTTGACTCAGACA
GACTCGGCATGGGATTTGGAAATTGCAGAAGTGTTATTTCACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGAATCACCCATTA
TGGCAAAACCAAGAAAAAAGTATAATGATGACAGTGACGATTCATATTTTACTTCCAGCTCAAGTTACTTTGACGAGCCAGTGGAGTTAA
GGAGCAGTTCTTTCTCTAGCTGGGATGACAGTTCAGATTCCTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGTTCTGAAAACCA
CAGGCTATTCAGACAGACCTACTGCTCGCCGCAAGCCAGATTATGAGCCAGTTGAAAATACAGATGAGGCCCAGAAGAAGTTTGGCAATG
TCAAGGCCATTTCATCAGATATGTATTTTGGAAGACAATCCCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCTGTCGGCAAGTT
CCTCCATAAGCTCGGCTGATCTGTTCGAGGAGCCGAGGAAGCAGCCAGCAGGGAACTACAGCCTGTCCAGTGTGCTGCCCAACGCCCCCG
ACATGGCGCAGTTCAAGCAGGGAGTGAGATCGGTTGCTGGAAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAATTCAGGATCGCT
ACGGTTCTTAATACTGAAGTCATGATGTGTATTTCCTGGAGAAATTCCTCTTTAAATGAACAAGTAACCACATCTCAGGCGGCAGTGAAG
TCCAGATAGTTTTGCAGATTGTTTTGCTACTTTTTCATATGGTATATGTTTCTGATTTTTAATATTTCTTTTGAGAAATTCTGAGTTCTG
ATGTAGGAGCTTTCCTGTGATTTCTGTTTCACGTTCCTTCCTGTCACACCCTCCTTTGGCGTCTCTGTGTATATCCTTGCTTTATTTTCT
TGGAACCTTTGATTTCAACACTGAGGGCCTGGAGACCTCGGCTCCTCCTGCTCCTGAACCAGGAGGCTTCATGTGGGGGAGGAGGAGAGG
TCTCCATGTGACACATGGGCTCAGGGCTGCCAGAATCAGCGGATGCTGGATGGGCCTGCAGAAACAACACTCACCACACACACTTCCTTC
AAAAGACCAAAAGTGACTGGTGTCTCGTGTGACAGATTGCTTCATTTATGTTTCTACATAGTAAGGTGACTGCCAAATAATATTTGAAGT
CATCTGTCTCTTTGTAAATTATTTTATATGACCTATAAATTTAAAAATGTTTTTCAGTGAGTGCTTTTAACAAACTTAAGCTTCTGCCCT
GCCAAGGGAATTAATGTTATCTTGTGAAAGGTGTTGCTGTTTGAATTGATGAGAAATGGAAGATGAGAACTCCCTAAGAGTTCTCATAAT
AAATCATCTCATCACAAATCAATACGGTATACAGAGTTAAAGTGGAATGAGGTAAGAAGATACAGCTACAGAAAATAGTTGCGTGTATGG
GAGAACAGTCATTGTAATTGGGTAGTTTTGTTAATAAATATTTTTAAATCTTGCTTTTCAGAAATTACCGAATGTGTATAAACAAATAAA
GAAAAATAATTTAGCTGTGTTTTAGACAGCATTAGAATATATTGTTCAGCACAGTAAAATATATTTGAAATTTGATAAGCCAAAAATGTG
GTTTTGAATGAATATTTTGTGAATCTTTCTTAAAAGCTCAAATTTGTAGACTTCTAAATAGAATAAACACTTGCAGCAGATGGCATTGCC

>89283_89283_7_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000380995_ARFGAP3_chr22_43219708_ENST00000263245_length(amino acids)=461AA_BP=152
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEVSSIIKKKPNQAKKGLGAKKGSLGAQ
KLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQ
TIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTD
EAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANG

--------------------------------------------------------------
>89283_89283_8_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000380995_ARFGAP3_chr22_43219708_ENST00000429508_length(transcript)=1760nt_BP=615nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGTATCCTCTATCA
TAAAAAAGAAACCAAATCAAGCTAAAAAAGGCCTTGGGGCCAAAAAAGGAAGTTTGGGAGCTCAGAAACTGGCAAACACATGCTTTAATG
AAATTGAAAAACAAGCTCAAGCTGCGGATAAAATGAAGGAGCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATCAATTGTTTCAT
CATTACGATTAGCCTATAAGGATCTTGAAATTCAAATGAAGAAAGACGAAAAGATGAACATTAGTGGCAAAAAAAATGTTGACTCAGACA
GACTCGGCATGGGATTTGGAAATTGCAGAAGTGTTATTTCACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGAATCACCCATTA
TGGCAAAACCAAGAAAAAAGTATAATGATGACAGTGACGATTCATATTTTACTTCCAGCTCAAGTTACTTTGACGAGCCAGTGGAGTTAA
GGAGCAGTTCTTTCTCTAGCTGGGATGACAGTTCAGATTCCTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGTTCTGAAAACCA
CAGGCTATTCAGACAGACCTACTGCTCGCCGCAAGCCAGATTATGAGCCAGTTGAAAATACAGATGAGGCCCAGAAGAAGTTTGGCAATG
TCAAGGCCATTTCATCAGATATGTATTTTGGAAGACAATCCCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCTGTCGGCAAGTT
CCTCCATAAGCTCGGCTGATCTGTTCGAGGAGCCGAGGAAGCAGCCAGCAGGGAACTACAGCCTGTCCAGTGTGCTGCCCAACGCCCCCG
ACATGGCGCAGTTCAAGCAGGGAGTGAGATCGGTTGCTGGAAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAATTCAGGATCGCT
ACGGTTCTTAATACTGAAGTCATGATGTGTATTTCCTGGAGAAATTCCTCTTTAAATGAACAAGTAACCACATCTCAGGCGGCAGTGAAG
TCCAGATAGTTTTGCAGATTGTTTTGCTACTTTTTCATATGGTATATGTTTCTGATTTTTAATATTTCTTTTGAGAAATTCTGAGTTCTG

>89283_89283_8_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000380995_ARFGAP3_chr22_43219708_ENST00000429508_length(amino acids)=461AA_BP=152
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEVSSIIKKKPNQAKKGLGAKKGSLGAQ
KLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQ
TIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTD
EAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANG

--------------------------------------------------------------
>89283_89283_9_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000380995_ARFGAP3_chr22_43219708_ENST00000437119_length(transcript)=1715nt_BP=615nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGTATCCTCTATCA
TAAAAAAGAAACCAAATCAAGCTAAAAAAGGCCTTGGGGCCAAAAAAGGAAGTTTGGGAGCTCAGAAACTGGCAAACACATGCTTTAATG
AAATTGAAAAACAAGCTCAAGCTGCGGATAAAATGAAGGAGCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATCAATTGTTTCAT
CATTACGATTAGCCTATAAGGATCTTGAAATTCAAATGAAGAAAGACGAAAAGATGAACATTAGTGGCAAAAAAAATGTTGACTCAGACA
GACTCGGCATGGGATTTGGAAATTGCAGAAGTGTTATTTCACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGAATCACCCATTA
TGGCAAAACCAAGAAAAAAGTATAATGATGACAGTGACGATTCATATTTTACTTCCAGCTCAAGTTACTTTGACGAGCCAGTGGAGTTAA
GGAGCAGTTCTTTCTCTAGCTGGGATGACAGTTCAGATTCCTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGTTCTGAAAACCA
CAGGCTATTCAGACAGACCTACTGCTCGCCGCAAGCCAGATTATGAGCCAGTTGAAAATACAGATGAGGCCCAGAAGAAGTTTGGCAATG
TCAAGGCCATTTCATCAGATATGTATTTTGGAAGACAATCCCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCTGTCGGCAAGTT
CCTCCATAAGCTCGGCTGATCTGTTCGAGGAGCCGAGGAAGCAGCCAGCAGGGAACTACAGCCTGTCCAGTGTGCTGCCCAACGCCCCCG
ACATGGCGCAGTTCAAGCAGGGAGTGAGATCGGTTGCTGGAAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAATTCAGGATCGCT
ACGGTTCTTAATACTGAAGTCATGATGTGTATTTCCTGGAGAAATTCCTCTTTAAATGAACAAGTAACCACATCTCAGGCGGCAGTGAAG
TCCAGATAGTTTTGCAGATTGTTTTGCTACTTTTTCATATGGTATATGTTTCTGATTTTTAATATTTCTTTTGAGAAATTCTGAGTTCTG

>89283_89283_9_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000380995_ARFGAP3_chr22_43219708_ENST00000437119_length(amino acids)=461AA_BP=152
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEVSSIIKKKPNQAKKGLGAKKGSLGAQ
KLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQ
TIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTD
EAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANG

--------------------------------------------------------------
>89283_89283_10_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000406733_ARFGAP3_chr22_43219708_ENST00000263245_length(transcript)=2719nt_BP=707nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGTATCCTCTAT
CATAAAAAAGAAACCAAATCAAGCTAAAAAAGGCCTTGGGGCCAAAAAAGGAAGTTTGGGAGCTCAGAAACTGGCAAACACATGCTTTAA
TGAAATTGAAAAACAAGCTCAAGCTGCGGATAAAATGAAGGAGCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATCAATTGTTTC
ATCATTACGATTAGCCTATAAGGATCTTGAAATTCAAATGAAGAAAGACGAAAAGATGAACATTAGTGGCAAAAAAAATGTTGACTCAGA
CAGACTCGGCATGGGATTTGGAAATTGCAGAAGTGTTATTTCACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGAATCACCCAT
TATGGCAAAACCAAGAAAAAAGTATAATGATGACAGTGACGATTCATATTTTACTTCCAGCTCAAGTTACTTTGACGAGCCAGTGGAGTT
AAGGAGCAGTTCTTTCTCTAGCTGGGATGACAGTTCAGATTCCTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGTTCTGAAAAC
CACAGGCTATTCAGACAGACCTACTGCTCGCCGCAAGCCAGATTATGAGCCAGTTGAAAATACAGATGAGGCCCAGAAGAAGTTTGGCAA
TGTCAAGGCCATTTCATCAGATATGTATTTTGGAAGACAATCCCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCTGTCGGCAAG
TTCCTCCATAAGCTCGGCTGATCTGTTCGAGGAGCCGAGGAAGCAGCCAGCAGGGAACTACAGCCTGTCCAGTGTGCTGCCCAACGCCCC
CGACATGGCGCAGTTCAAGCAGGGAGTGAGATCGGTTGCTGGAAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAATTCAGGATCG
CTACGGTTCTTAATACTGAAGTCATGATGTGTATTTCCTGGAGAAATTCCTCTTTAAATGAACAAGTAACCACATCTCAGGCGGCAGTGA
AGTCCAGATAGTTTTGCAGATTGTTTTGCTACTTTTTCATATGGTATATGTTTCTGATTTTTAATATTTCTTTTGAGAAATTCTGAGTTC
TGATGTAGGAGCTTTCCTGTGATTTCTGTTTCACGTTCCTTCCTGTCACACCCTCCTTTGGCGTCTCTGTGTATATCCTTGCTTTATTTT
CTTGGAACCTTTGATTTCAACACTGAGGGCCTGGAGACCTCGGCTCCTCCTGCTCCTGAACCAGGAGGCTTCATGTGGGGGAGGAGGAGA
GGTCTCCATGTGACACATGGGCTCAGGGCTGCCAGAATCAGCGGATGCTGGATGGGCCTGCAGAAACAACACTCACCACACACACTTCCT
TCAAAAGACCAAAAGTGACTGGTGTCTCGTGTGACAGATTGCTTCATTTATGTTTCTACATAGTAAGGTGACTGCCAAATAATATTTGAA
GTCATCTGTCTCTTTGTAAATTATTTTATATGACCTATAAATTTAAAAATGTTTTTCAGTGAGTGCTTTTAACAAACTTAAGCTTCTGCC
CTGCCAAGGGAATTAATGTTATCTTGTGAAAGGTGTTGCTGTTTGAATTGATGAGAAATGGAAGATGAGAACTCCCTAAGAGTTCTCATA
ATAAATCATCTCATCACAAATCAATACGGTATACAGAGTTAAAGTGGAATGAGGTAAGAAGATACAGCTACAGAAAATAGTTGCGTGTAT
GGGAGAACAGTCATTGTAATTGGGTAGTTTTGTTAATAAATATTTTTAAATCTTGCTTTTCAGAAATTACCGAATGTGTATAAACAAATA
AAGAAAAATAATTTAGCTGTGTTTTAGACAGCATTAGAATATATTGTTCAGCACAGTAAAATATATTTGAAATTTGATAAGCCAAAAATG
TGGTTTTGAATGAATATTTTGTGAATCTTTCTTAAAAGCTCAAATTTGTAGACTTCTAAATAGAATAAACACTTGCAGCAGATGGCATTG

>89283_89283_10_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000406733_ARFGAP3_chr22_43219708_ENST00000263245_length(amino acids)=463AA_BP=154
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEVSSIIKKKPNQAKKGLGAKKGSLG
AQKLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSD
MQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVEN
TDEAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFA

--------------------------------------------------------------
>89283_89283_11_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000406733_ARFGAP3_chr22_43219708_ENST00000429508_length(transcript)=1852nt_BP=707nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGTATCCTCTAT
CATAAAAAAGAAACCAAATCAAGCTAAAAAAGGCCTTGGGGCCAAAAAAGGAAGTTTGGGAGCTCAGAAACTGGCAAACACATGCTTTAA
TGAAATTGAAAAACAAGCTCAAGCTGCGGATAAAATGAAGGAGCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATCAATTGTTTC
ATCATTACGATTAGCCTATAAGGATCTTGAAATTCAAATGAAGAAAGACGAAAAGATGAACATTAGTGGCAAAAAAAATGTTGACTCAGA
CAGACTCGGCATGGGATTTGGAAATTGCAGAAGTGTTATTTCACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGAATCACCCAT
TATGGCAAAACCAAGAAAAAAGTATAATGATGACAGTGACGATTCATATTTTACTTCCAGCTCAAGTTACTTTGACGAGCCAGTGGAGTT
AAGGAGCAGTTCTTTCTCTAGCTGGGATGACAGTTCAGATTCCTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGTTCTGAAAAC
CACAGGCTATTCAGACAGACCTACTGCTCGCCGCAAGCCAGATTATGAGCCAGTTGAAAATACAGATGAGGCCCAGAAGAAGTTTGGCAA
TGTCAAGGCCATTTCATCAGATATGTATTTTGGAAGACAATCCCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCTGTCGGCAAG
TTCCTCCATAAGCTCGGCTGATCTGTTCGAGGAGCCGAGGAAGCAGCCAGCAGGGAACTACAGCCTGTCCAGTGTGCTGCCCAACGCCCC
CGACATGGCGCAGTTCAAGCAGGGAGTGAGATCGGTTGCTGGAAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAATTCAGGATCG
CTACGGTTCTTAATACTGAAGTCATGATGTGTATTTCCTGGAGAAATTCCTCTTTAAATGAACAAGTAACCACATCTCAGGCGGCAGTGA
AGTCCAGATAGTTTTGCAGATTGTTTTGCTACTTTTTCATATGGTATATGTTTCTGATTTTTAATATTTCTTTTGAGAAATTCTGAGTTC

>89283_89283_11_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000406733_ARFGAP3_chr22_43219708_ENST00000429508_length(amino acids)=463AA_BP=154
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEVSSIIKKKPNQAKKGLGAKKGSLG
AQKLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSD
MQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVEN
TDEAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFA

--------------------------------------------------------------
>89283_89283_12_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000406733_ARFGAP3_chr22_43219708_ENST00000437119_length(transcript)=1807nt_BP=707nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGTATCCTCTAT
CATAAAAAAGAAACCAAATCAAGCTAAAAAAGGCCTTGGGGCCAAAAAAGGAAGTTTGGGAGCTCAGAAACTGGCAAACACATGCTTTAA
TGAAATTGAAAAACAAGCTCAAGCTGCGGATAAAATGAAGGAGCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATCAATTGTTTC
ATCATTACGATTAGCCTATAAGGATCTTGAAATTCAAATGAAGAAAGACGAAAAGATGAACATTAGTGGCAAAAAAAATGTTGACTCAGA
CAGACTCGGCATGGGATTTGGAAATTGCAGAAGTGTTATTTCACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGAATCACCCAT
TATGGCAAAACCAAGAAAAAAGTATAATGATGACAGTGACGATTCATATTTTACTTCCAGCTCAAGTTACTTTGACGAGCCAGTGGAGTT
AAGGAGCAGTTCTTTCTCTAGCTGGGATGACAGTTCAGATTCCTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGTTCTGAAAAC
CACAGGCTATTCAGACAGACCTACTGCTCGCCGCAAGCCAGATTATGAGCCAGTTGAAAATACAGATGAGGCCCAGAAGAAGTTTGGCAA
TGTCAAGGCCATTTCATCAGATATGTATTTTGGAAGACAATCCCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCTGTCGGCAAG
TTCCTCCATAAGCTCGGCTGATCTGTTCGAGGAGCCGAGGAAGCAGCCAGCAGGGAACTACAGCCTGTCCAGTGTGCTGCCCAACGCCCC
CGACATGGCGCAGTTCAAGCAGGGAGTGAGATCGGTTGCTGGAAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAATTCAGGATCG
CTACGGTTCTTAATACTGAAGTCATGATGTGTATTTCCTGGAGAAATTCCTCTTTAAATGAACAAGTAACCACATCTCAGGCGGCAGTGA
AGTCCAGATAGTTTTGCAGATTGTTTTGCTACTTTTTCATATGGTATATGTTTCTGATTTTTAATATTTCTTTTGAGAAATTCTGAGTTC

>89283_89283_12_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000406733_ARFGAP3_chr22_43219708_ENST00000437119_length(amino acids)=463AA_BP=154
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEVSSIIKKKPNQAKKGLGAKKGSLG
AQKLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSD
MQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVEN
TDEAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFA

--------------------------------------------------------------
>89283_89283_13_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000407381_ARFGAP3_chr22_43219708_ENST00000263245_length(transcript)=2587nt_BP=575nt
CTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCG
CGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCAT
CCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACC
AGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCT
GGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCC
CACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAA
GTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGTATCCTCTATCATAAAAAAGAAACCAAATCAAGCTAAAAAAGGCCTTGGGGC
CAAAAAAGGAAGTTTGGGAGCTCAGAAACTGGCAAACACATGCTTTAATGAAATTGAAAAACAAGCTCAAGCTGCGGATAAAATGAAGGA
GCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATCAATTGTTTCATCATTACGATTAGCCTATAAGGATCTTGAAATTCAAATGAA
GAAAGACGAAAAGATGAACATTAGTGGCAAAAAAAATGTTGACTCAGACAGACTCGGCATGGGATTTGGAAATTGCAGAAGTGTTATTTC
ACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGAATCACCCATTATGGCAAAACCAAGAAAAAAGTATAATGATGACAGTGACGA
TTCATATTTTACTTCCAGCTCAAGTTACTTTGACGAGCCAGTGGAGTTAAGGAGCAGTTCTTTCTCTAGCTGGGATGACAGTTCAGATTC
CTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGTTCTGAAAACCACAGGCTATTCAGACAGACCTACTGCTCGCCGCAAGCCAGA
TTATGAGCCAGTTGAAAATACAGATGAGGCCCAGAAGAAGTTTGGCAATGTCAAGGCCATTTCATCAGATATGTATTTTGGAAGACAATC
CCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCTGTCGGCAAGTTCCTCCATAAGCTCGGCTGATCTGTTCGAGGAGCCGAGGAA
GCAGCCAGCAGGGAACTACAGCCTGTCCAGTGTGCTGCCCAACGCCCCCGACATGGCGCAGTTCAAGCAGGGAGTGAGATCGGTTGCTGG
AAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAATTCAGGATCGCTACGGTTCTTAATACTGAAGTCATGATGTGTATTTCCTGGA
GAAATTCCTCTTTAAATGAACAAGTAACCACATCTCAGGCGGCAGTGAAGTCCAGATAGTTTTGCAGATTGTTTTGCTACTTTTTCATAT
GGTATATGTTTCTGATTTTTAATATTTCTTTTGAGAAATTCTGAGTTCTGATGTAGGAGCTTTCCTGTGATTTCTGTTTCACGTTCCTTC
CTGTCACACCCTCCTTTGGCGTCTCTGTGTATATCCTTGCTTTATTTTCTTGGAACCTTTGATTTCAACACTGAGGGCCTGGAGACCTCG
GCTCCTCCTGCTCCTGAACCAGGAGGCTTCATGTGGGGGAGGAGGAGAGGTCTCCATGTGACACATGGGCTCAGGGCTGCCAGAATCAGC
GGATGCTGGATGGGCCTGCAGAAACAACACTCACCACACACACTTCCTTCAAAAGACCAAAAGTGACTGGTGTCTCGTGTGACAGATTGC
TTCATTTATGTTTCTACATAGTAAGGTGACTGCCAAATAATATTTGAAGTCATCTGTCTCTTTGTAAATTATTTTATATGACCTATAAAT
TTAAAAATGTTTTTCAGTGAGTGCTTTTAACAAACTTAAGCTTCTGCCCTGCCAAGGGAATTAATGTTATCTTGTGAAAGGTGTTGCTGT
TTGAATTGATGAGAAATGGAAGATGAGAACTCCCTAAGAGTTCTCATAATAAATCATCTCATCACAAATCAATACGGTATACAGAGTTAA
AGTGGAATGAGGTAAGAAGATACAGCTACAGAAAATAGTTGCGTGTATGGGAGAACAGTCATTGTAATTGGGTAGTTTTGTTAATAAATA
TTTTTAAATCTTGCTTTTCAGAAATTACCGAATGTGTATAAACAAATAAAGAAAAATAATTTAGCTGTGTTTTAGACAGCATTAGAATAT
ATTGTTCAGCACAGTAAAATATATTTGAAATTTGATAAGCCAAAAATGTGGTTTTGAATGAATATTTTGTGAATCTTTCTTAAAAGCTCA

>89283_89283_13_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000407381_ARFGAP3_chr22_43219708_ENST00000263245_length(amino acids)=461AA_BP=152
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEVSSIIKKKPNQAKKGLGAKKGSLGAQ
KLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQ
TIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTD
EAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANG

--------------------------------------------------------------
>89283_89283_14_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000407381_ARFGAP3_chr22_43219708_ENST00000429508_length(transcript)=1720nt_BP=575nt
CTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCG
CGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCAT
CCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACC
AGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCT
GGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCC
CACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAA
GTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGTATCCTCTATCATAAAAAAGAAACCAAATCAAGCTAAAAAAGGCCTTGGGGC
CAAAAAAGGAAGTTTGGGAGCTCAGAAACTGGCAAACACATGCTTTAATGAAATTGAAAAACAAGCTCAAGCTGCGGATAAAATGAAGGA
GCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATCAATTGTTTCATCATTACGATTAGCCTATAAGGATCTTGAAATTCAAATGAA
GAAAGACGAAAAGATGAACATTAGTGGCAAAAAAAATGTTGACTCAGACAGACTCGGCATGGGATTTGGAAATTGCAGAAGTGTTATTTC
ACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGAATCACCCATTATGGCAAAACCAAGAAAAAAGTATAATGATGACAGTGACGA
TTCATATTTTACTTCCAGCTCAAGTTACTTTGACGAGCCAGTGGAGTTAAGGAGCAGTTCTTTCTCTAGCTGGGATGACAGTTCAGATTC
CTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGTTCTGAAAACCACAGGCTATTCAGACAGACCTACTGCTCGCCGCAAGCCAGA
TTATGAGCCAGTTGAAAATACAGATGAGGCCCAGAAGAAGTTTGGCAATGTCAAGGCCATTTCATCAGATATGTATTTTGGAAGACAATC
CCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCTGTCGGCAAGTTCCTCCATAAGCTCGGCTGATCTGTTCGAGGAGCCGAGGAA
GCAGCCAGCAGGGAACTACAGCCTGTCCAGTGTGCTGCCCAACGCCCCCGACATGGCGCAGTTCAAGCAGGGAGTGAGATCGGTTGCTGG
AAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAATTCAGGATCGCTACGGTTCTTAATACTGAAGTCATGATGTGTATTTCCTGGA
GAAATTCCTCTTTAAATGAACAAGTAACCACATCTCAGGCGGCAGTGAAGTCCAGATAGTTTTGCAGATTGTTTTGCTACTTTTTCATAT
GGTATATGTTTCTGATTTTTAATATTTCTTTTGAGAAATTCTGAGTTCTGATGTAGGAGCTTTCCTGTGATTTCTGTTTCACGTTCCTTC

>89283_89283_14_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000407381_ARFGAP3_chr22_43219708_ENST00000429508_length(amino acids)=461AA_BP=152
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEVSSIIKKKPNQAKKGLGAKKGSLGAQ
KLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQ
TIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTD
EAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANG

--------------------------------------------------------------
>89283_89283_15_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000407381_ARFGAP3_chr22_43219708_ENST00000437119_length(transcript)=1675nt_BP=575nt
CTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCG
CGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCAT
CCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACC
AGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCT
GGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCC
CACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAA
GTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGTATCCTCTATCATAAAAAAGAAACCAAATCAAGCTAAAAAAGGCCTTGGGGC
CAAAAAAGGAAGTTTGGGAGCTCAGAAACTGGCAAACACATGCTTTAATGAAATTGAAAAACAAGCTCAAGCTGCGGATAAAATGAAGGA
GCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATCAATTGTTTCATCATTACGATTAGCCTATAAGGATCTTGAAATTCAAATGAA
GAAAGACGAAAAGATGAACATTAGTGGCAAAAAAAATGTTGACTCAGACAGACTCGGCATGGGATTTGGAAATTGCAGAAGTGTTATTTC
ACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGAATCACCCATTATGGCAAAACCAAGAAAAAAGTATAATGATGACAGTGACGA
TTCATATTTTACTTCCAGCTCAAGTTACTTTGACGAGCCAGTGGAGTTAAGGAGCAGTTCTTTCTCTAGCTGGGATGACAGTTCAGATTC
CTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGTTCTGAAAACCACAGGCTATTCAGACAGACCTACTGCTCGCCGCAAGCCAGA
TTATGAGCCAGTTGAAAATACAGATGAGGCCCAGAAGAAGTTTGGCAATGTCAAGGCCATTTCATCAGATATGTATTTTGGAAGACAATC
CCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCTGTCGGCAAGTTCCTCCATAAGCTCGGCTGATCTGTTCGAGGAGCCGAGGAA
GCAGCCAGCAGGGAACTACAGCCTGTCCAGTGTGCTGCCCAACGCCCCCGACATGGCGCAGTTCAAGCAGGGAGTGAGATCGGTTGCTGG
AAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAATTCAGGATCGCTACGGTTCTTAATACTGAAGTCATGATGTGTATTTCCTGGA
GAAATTCCTCTTTAAATGAACAAGTAACCACATCTCAGGCGGCAGTGAAGTCCAGATAGTTTTGCAGATTGTTTTGCTACTTTTTCATAT

>89283_89283_15_TBC1D22A-ARFGAP3_TBC1D22A_chr22_47189738_ENST00000407381_ARFGAP3_chr22_43219708_ENST00000437119_length(amino acids)=461AA_BP=152
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEVSSIIKKKPNQAKKGLGAKKGSLGAQ
KLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQ
TIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTD
EAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TBC1D22A-ARFGAP3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TBC1D22A-ARFGAP3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TBC1D22A-ARFGAP3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource