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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TBC1D22A-OTUD7A (FusionGDB2 ID:89301)

Fusion Gene Summary for TBC1D22A-OTUD7A

check button Fusion gene summary
Fusion gene informationFusion gene name: TBC1D22A-OTUD7A
Fusion gene ID: 89301
HgeneTgene
Gene symbol

TBC1D22A

OTUD7A

Gene ID

25771

161725

Gene nameTBC1 domain family member 22AOTU deubiquitinase 7A
SynonymsC22orf4|HSC79E021C15orf16|C16ORF15|CEZANNE2|OTUD7
Cytomap

22q13.31

15q13.3

Type of geneprotein-codingprotein-coding
DescriptionTBC1 domain family member 22Aputative GTPase activatorOTU domain-containing protein 7AOTU domain-containing 7Acezanne 2zinc finger protein Cezanne 2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000337137, ENST00000355704, 
ENST00000380995, ENST00000406733, 
ENST00000407381, ENST00000472791, 
ENST00000307050, ENST00000382902, 
Fusion gene scores* DoF score34 X 18 X 14=85685 X 5 X 3=75
# samples 375
** MAII scorelog2(37/8568*10)=-4.53336130423394
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TBC1D22A [Title/Abstract] AND OTUD7A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTBC1D22A(47308084)-OTUD7A(31862400), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneOTUD7A

GO:0035871

protein K11-linked deubiquitination

23827681


check buttonFusion gene breakpoints across TBC1D22A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across OTUD7A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-BF-A5EQ-01ATBC1D22Achr22

47308084

-OTUD7Achr15

31862400

-
ChimerDB4SKCMTCGA-BF-A5EQ-01ATBC1D22Achr22

47308084

+OTUD7Achr15

31862400

-


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Fusion Gene ORF analysis for TBC1D22A-OTUD7A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000337137ENST00000307050TBC1D22Achr22

47308084

+OTUD7Achr15

31862400

-
In-frameENST00000337137ENST00000382902TBC1D22Achr22

47308084

+OTUD7Achr15

31862400

-
In-frameENST00000355704ENST00000307050TBC1D22Achr22

47308084

+OTUD7Achr15

31862400

-
In-frameENST00000355704ENST00000382902TBC1D22Achr22

47308084

+OTUD7Achr15

31862400

-
In-frameENST00000380995ENST00000307050TBC1D22Achr22

47308084

+OTUD7Achr15

31862400

-
In-frameENST00000380995ENST00000382902TBC1D22Achr22

47308084

+OTUD7Achr15

31862400

-
In-frameENST00000406733ENST00000307050TBC1D22Achr22

47308084

+OTUD7Achr15

31862400

-
In-frameENST00000406733ENST00000382902TBC1D22Achr22

47308084

+OTUD7Achr15

31862400

-
In-frameENST00000407381ENST00000307050TBC1D22Achr22

47308084

+OTUD7Achr15

31862400

-
In-frameENST00000407381ENST00000382902TBC1D22Achr22

47308084

+OTUD7Achr15

31862400

-
intron-3CDSENST00000472791ENST00000307050TBC1D22Achr22

47308084

+OTUD7Achr15

31862400

-
intron-3CDSENST00000472791ENST00000382902TBC1D22Achr22

47308084

+OTUD7Achr15

31862400

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000337137TBC1D22Achr2247308084+ENST00000382902OTUD7Achr1531862400-4000118116638311221
ENST00000337137TBC1D22Achr2247308084+ENST00000307050OTUD7Achr1531862400-3979118116638101214
ENST00000380995TBC1D22Achr2247308084+ENST00000382902OTUD7Achr1531862400-3989117015538201221
ENST00000380995TBC1D22Achr2247308084+ENST00000307050OTUD7Achr1531862400-3968117015537991214
ENST00000407381TBC1D22Achr2247308084+ENST00000382902OTUD7Achr1531862400-377295311536031162
ENST00000407381TBC1D22Achr2247308084+ENST00000307050OTUD7Achr1531862400-375195311535821155
ENST00000355704TBC1D22Achr2247308084+ENST00000382902OTUD7Achr1531862400-370688710635371143
ENST00000355704TBC1D22Achr2247308084+ENST00000307050OTUD7Achr1531862400-368588710635161136
ENST00000406733TBC1D22Achr2247308084+ENST00000382902OTUD7Achr1531862400-4081126224139121223
ENST00000406733TBC1D22Achr2247308084+ENST00000307050OTUD7Achr1531862400-4060126224138911216

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000337137ENST00000382902TBC1D22Achr2247308084+OTUD7Achr1531862400-0.0046865310.9953134
ENST00000337137ENST00000307050TBC1D22Achr2247308084+OTUD7Achr1531862400-0.0069316170.99306846
ENST00000380995ENST00000382902TBC1D22Achr2247308084+OTUD7Achr1531862400-0.0046120170.995388
ENST00000380995ENST00000307050TBC1D22Achr2247308084+OTUD7Achr1531862400-0.006833340.9931666
ENST00000407381ENST00000382902TBC1D22Achr2247308084+OTUD7Achr1531862400-0.0035477730.9964522
ENST00000407381ENST00000307050TBC1D22Achr2247308084+OTUD7Achr1531862400-0.0053445390.9946555
ENST00000355704ENST00000382902TBC1D22Achr2247308084+OTUD7Achr1531862400-0.0033568910.9966432
ENST00000355704ENST00000307050TBC1D22Achr2247308084+OTUD7Achr1531862400-0.005098870.99490106
ENST00000406733ENST00000382902TBC1D22Achr2247308084+OTUD7Achr1531862400-0.0055212190.9944788
ENST00000406733ENST00000307050TBC1D22Achr2247308084+OTUD7Achr1531862400-0.0082049580.991795

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Fusion Genomic Features for TBC1D22A-OTUD7A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TBC1D22A-OTUD7A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:47308084/chr15:31862400)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneOTUD7Achr22:47308084chr15:31862400ENST00000307050011199_37450927.0DomainOTU
TgeneOTUD7Achr22:47308084chr15:31862400ENST00000382902011199_37450934.0DomainOTU
TgeneOTUD7Achr22:47308084chr15:31862400ENST00000307050011494_50950927.0MotifNuclear localization signal
TgeneOTUD7Achr22:47308084chr15:31862400ENST00000382902011494_50950934.0MotifNuclear localization signal
TgeneOTUD7Achr22:47308084chr15:31862400ENST00000307050011168_41050927.0RegionTRAF-binding
TgeneOTUD7Achr22:47308084chr15:31862400ENST00000307050011183_44950927.0RegionCatalytic
TgeneOTUD7Achr22:47308084chr15:31862400ENST00000382902011168_41050934.0RegionTRAF-binding
TgeneOTUD7Achr22:47308084chr15:31862400ENST00000382902011183_44950934.0RegionCatalytic
TgeneOTUD7Achr22:47308084chr15:31862400ENST00000307050011884_91950927.0Zinc fingerA20-type
TgeneOTUD7Achr22:47308084chr15:31862400ENST00000382902011884_91950934.0Zinc fingerA20-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTBC1D22Achr22:47308084chr15:31862400ENST00000337137+813222_446338518.0DomainRab-GAP TBC
HgeneTBC1D22Achr22:47308084chr15:31862400ENST00000355704+611222_446260440.0DomainRab-GAP TBC
HgeneTBC1D22Achr22:47308084chr15:31862400ENST00000380995+89222_446291325.0DomainRab-GAP TBC


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Fusion Gene Sequence for TBC1D22A-OTUD7A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>89301_89301_1_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000337137_OTUD7A_chr15_31862400_ENST00000307050_length(transcript)=3979nt_BP=1181nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAG
TGCCAGCGATGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCT
CAGCAGCTCAGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGAGGAATT
ACGGAGGTTGAGCTGGTCCGGAATCCCTAAGCCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCG
GAGACCAGCCACTCTCCAGAGAAAACAAAAAGAATATTTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGA
CACATACAGGCAGATCCACATAGACATCCCTCGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGAT
CTTGTTCATATGGGCGATCCGCCACCCAGCCAGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTG
TGAATACATAGGCAAAAACTGGGACCTGACAGCCGCTCTGAGCGACTATGAGCAGCTCCGCCAGGTGCACACAGCCAATCTGCCACATGT
GTTCAATGAAGGGCGGGGTCCCAAGCAGCCAGAGCGAGAGCCACAGCCCGGGCACAAGGTGGAGCGACCCTGCCTGCAGAGGCAGGACGA
CATTGCCCAAGAAAAGCGGCTTTCCCGGGGGATTTCCCACGCCAGCTCAGCCATCGTCTCCCTGGCCCGGTCCCACGTGGCAAGTGAATG
CAACAACGAGCAGTTCCCCCTGGAGATGCCAATCTACACATTCCAGTTGCCAGACCTGAGCGTGTACAGCGAGGATTTCAGGAGCTTCAT
CGAGCGGGACTTGATCGAGCAGGCAACAATGGTGGCTTTGGAGCAGGCAGGTCGCCTGAACTGGTGGTCCACTGTGTGCACGAGCTGTAA
ACGGCTTCTTCCTCTGGCCACAACAGGGGATGGGAACTGCCTTTTACATGCTGCTTCACTGGGAATGTGGGGGTTTCACGACCGGGACCT
GGTGTTACGGAAAGCTCTCTATACCATGATGAGGACGGGAGCTGAGAGGGAAGCCCTGAAGCGGAGGTGGAGGTGGCAGCAGACGCAGCA
GAATAAGGAGGAGGAGTGGGAGCGGGAGTGGACGGAGCTGCTGAAGCTGGCCTCCAGCGAGCCGCGCACACACTTCAGCAAGAATGGCGG
CACGGGCGGGGGTGTGGACAACTCTGAGGACCCCGTGTACGAGAGCCTGGAAGAGTTCCACGTTTTTGTCCTAGCCCATATATTAAGAAG
GCCCATCGTTGTTGTGGCAGATACAATGTTAAGAGACTCAGGTGGAGAAGCGTTCGCACCCATCCCATTCGGAGGGATCTACCTGCCCTT
GGAGGTCCCTCCCAACAGATGCCACTGCTCGCCTCTGGTTCTGGCCTATGATCAAGCCCATTTCTCTGCCCTTGTGTCCATGGAACAGAG
AGACCAGCAAAGAGAACAAGCCGTGATCCCCCTGACGGATTCTGAGCACAAGCTGCTGCCTCTGCACTTTGCAGTGGACCCTGGCAAGGA
CTGGGAGTGGGGGAAAGACGACAACGATAACGCCCGGCTGGCCCACCTTATCCTGTCGCTAGAAGCCAAGCTGAACCTTCTGCACAGCTA
CATGAACGTGACGTGGATCCGGATCCCCTCCGAGACACGGGCGCCCCTGGCACAGCCGGAGTCTCCCACGGCCTCGGCAGGGGAGGACGT
GCAGTCCCTGGCCGACTCGCTGGACTCGGACCGCGATTCGGTGTGCAGCAATTCTAACAGCAATAACGGCAAGAACGGCAAGGACAAGGA
GAAGGAGAAGCAGCGCAAGGAGAAGGACAAGACGCGCGCCGACTCCGTGGCCAACAAGCTGGGCAGCTTCAGCAAGACGCTGGGCATCAA
GCTGAAGAAAAACATGGGCGGCCTCGGCGGCCTGGTGCACGGCAAGATGGGCCGCGCCAACTCCGCCAATGGCAAGAACGGGGACTCGGC
CGAGCGGGGCAAGGAGAAGAAGGCCAAGTCGCGCAAGGGCAGCAAGGAGGAGTCTGGTGCGTCGGCCAGCACGTCGCCGTCGGAAAAGAC
CACGCCGTCGCCCACAGACAAGGCAGCGGGCGCGTCGCCGGCGGAGAAGGGCGGTGGGCCGCGGGGCGACGCCTGGAAGTACAGCACGGA
TGTGAAGCTGAGCCTCAACATCCTGCGCGCCGCCATGCAGGGGGAGCGCAAGTTCATCTTCGCCGGCCTGCTGCTCACCAGCCACCGGCA
CCAGTTCCACGAGGAGATGATCGGCTACTACCTGACGAGCGCGCAGGAGCGCTTCAGCGCCGAGCAGGAGCAGCGGCGCCGCGACGCCGC
TACTGCGGCCGCCGCTGCCGCCGCCGCCGCCGCCGCCACGGCCAAGCGGCCGCCGCGCAGACCGGAGACGGAGGGCGTGCCGGTCCCGGA
GCGCGCCTCTCCGGGCCCACCCACGCAGCTGGTGCTCAAGCTCAAGGAGCGGCCGAGCCCCGGGCCCGCGGCAGGGCGTGCGGCGCGGGC
GGCGGCGGGCGGCACGGCCTCCCCGGGGGGAGGCGCGCGGCGTGCGAGCGCCAGCGGACCAGTGCCTGGCCGCAGCCCCCCGGCGCCAGC
GCGCCAGAGCGTCATCCACGTGCAGGCGTCGGGCGCGCGGGACGAGGCGTGCGCGCCGGCCGTGGGGGCGCTGCGGCCGTGCGCCACGTA
CCCGCAGCAGAACCGCTCGCTGTCGTCGCAGAGCTACAGCCCGGCGCGCGCCGCCGCCCTGCGCACCGTCAACACGGTCGAGTCGCTGGC
GCGCGCGGTGCCCGGGGCCCTACCGGGCGCGGCGGGGACGGCGGGGGCGGCCGAGCACAAGTCGCAGACCTACACCAACGGCTTCGGCGC
CCTGCGCGACGGCCTGGAGTTCGCCGACGCCGACGCGCCGACCGCGCGCTCGAACGGTGAGTGCGGCCGTGGCGGCCCGGGGCCGGTGCA
GCGGCGCTGCCAGCGCGAGAACTGTGCGTTCTACGGGCGCGCCGAGACCGAGCACTACTGCTCCTACTGCTACCGCGAGGAGCTGCGGCG
GCGGCGCGAGGCGCGCGGGGCCCGGCCCTGAGCGGCGCGGCGCGGCGCGGGCGGCGAGGTTCTACCTTCGAGGATTTCTTTTCCATTGTG
TCGGTGTCTTTTTTACATGCCCTGGTCCACCGGAAGGCCGGCGCCTCCTCTGTCAGTGCCGTGTACGTGTTTGGTCAAACGTTCCTAATG

>89301_89301_1_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000337137_OTUD7A_chr15_31862400_ENST00000307050_length(amino acids)=1214AA_BP=338
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRND
EVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIGKNWDLTAALSDYEQLRQVHTA
NLPHVFNEGRGPKQPEREPQPGHKVERPCLQRQDDIAQEKRLSRGISHASSAIVSLARSHVASECNNEQFPLEMPIYTFQLPDLSVYSED
FRSFIERDLIEQATMVALEQAGRLNWWSTVCTSCKRLLPLATTGDGNCLLHAASLGMWGFHDRDLVLRKALYTMMRTGAEREALKRRWRW
QQTQQNKEEEWEREWTELLKLASSEPRTHFSKNGGTGGGVDNSEDPVYESLEEFHVFVLAHILRRPIVVVADTMLRDSGGEAFAPIPFGG
IYLPLEVPPNRCHCSPLVLAYDQAHFSALVSMEQRDQQREQAVIPLTDSEHKLLPLHFAVDPGKDWEWGKDDNDNARLAHLILSLEAKLN
LLHSYMNVTWIRIPSETRAPLAQPESPTASAGEDVQSLADSLDSDRDSVCSNSNSNNGKNGKDKEKEKQRKEKDKTRADSVANKLGSFSK
TLGIKLKKNMGGLGGLVHGKMGRANSANGKNGDSAERGKEKKAKSRKGSKEESGASASTSPSEKTTPSPTDKAAGASPAEKGGGPRGDAW
KYSTDVKLSLNILRAAMQGERKFIFAGLLLTSHRHQFHEEMIGYYLTSAQERFSAEQEQRRRDAATAAAAAAAAAAATAKRPPRRPETEG
VPVPERASPGPPTQLVLKLKERPSPGPAAGRAARAAAGGTASPGGGARRASASGPVPGRSPPAPARQSVIHVQASGARDEACAPAVGALR
PCATYPQQNRSLSSQSYSPARAAALRTVNTVESLARAVPGALPGAAGTAGAAEHKSQTYTNGFGALRDGLEFADADAPTARSNGECGRGG

--------------------------------------------------------------
>89301_89301_2_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000337137_OTUD7A_chr15_31862400_ENST00000382902_length(transcript)=4000nt_BP=1181nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAG
TGCCAGCGATGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCT
CAGCAGCTCAGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGAGGAATT
ACGGAGGTTGAGCTGGTCCGGAATCCCTAAGCCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCG
GAGACCAGCCACTCTCCAGAGAAAACAAAAAGAATATTTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGA
CACATACAGGCAGATCCACATAGACATCCCTCGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGAT
CTTGTTCATATGGGCGATCCGCCACCCAGCCAGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTG
TGAATACATAGGCAAAAACTGGGACCTGACAGCCGCTCTGAGCGACTATGAGCAGCTCCGCCAGGTGCACACAGCCAATCTGCCACATGT
GTTCAATGAAGGGCGGGGTCCCAAGCAGCCAGAGCGAGAGCCACAGCCCGGGCACAAGGTGGAGCGACCCTGCCTGCAGAGGCAGGACGA
CATTGCCCAAGAAAAGCGGCTTTCCCGGGGGATTTCCCACGCCAGCTCAGCCATCGTCTCCCTGGCCCGGTCCCACGTGGCAAGTGAATG
CAACAACGAGCAGTTCCCCCTGGAGATGCCAATCTACACATTCCAGTTGCCAGACCTGAGCGTGTACAGCGAGGATTTCAGGAGCTTCAT
CGAGCGGGACTTGATCGAGCAGGCAACAATGGTGGCTTTGGAGCAGGCAGGTCGCCTGAACTGGTGGTCCACTGTGTGCACGAGCTGTAA
ACGGCTTCTTCCTCTGGCCACAACAGGGGATGGGAACTGCCTTTTACATGCTGCTTCACTGGGAATGTGGGGGTTTCACGACCGGGACCT
GGTGTTACGGAAAGCTCTCTATACCATGATGAGGACGGGAGCTGAGAGGGAAGCCCTGAAGCGGAGGTGGAGGTGGCAGCAGACGCAGCA
GAATAAGGAGTCAGGGCTGGTGTACACAGAGGAGGAGTGGGAGCGGGAGTGGACGGAGCTGCTGAAGCTGGCCTCCAGCGAGCCGCGCAC
ACACTTCAGCAAGAATGGCGGCACGGGCGGGGGTGTGGACAACTCTGAGGACCCCGTGTACGAGAGCCTGGAAGAGTTCCACGTTTTTGT
CCTAGCCCATATATTAAGAAGGCCCATCGTTGTTGTGGCAGATACAATGTTAAGAGACTCAGGTGGAGAAGCGTTCGCACCCATCCCATT
CGGAGGGATCTACCTGCCCTTGGAGGTCCCTCCCAACAGATGCCACTGCTCGCCTCTGGTTCTGGCCTATGATCAAGCCCATTTCTCTGC
CCTTGTGTCCATGGAACAGAGAGACCAGCAAAGAGAACAAGCCGTGATCCCCCTGACGGATTCTGAGCACAAGCTGCTGCCTCTGCACTT
TGCAGTGGACCCTGGCAAGGACTGGGAGTGGGGGAAAGACGACAACGATAACGCCCGGCTGGCCCACCTTATCCTGTCGCTAGAAGCCAA
GCTGAACCTTCTGCACAGCTACATGAACGTGACGTGGATCCGGATCCCCTCCGAGACACGGGCGCCCCTGGCACAGCCGGAGTCTCCCAC
GGCCTCGGCAGGGGAGGACGTGCAGTCCCTGGCCGACTCGCTGGACTCGGACCGCGATTCGGTGTGCAGCAATTCTAACAGCAATAACGG
CAAGAACGGCAAGGACAAGGAGAAGGAGAAGCAGCGCAAGGAGAAGGACAAGACGCGCGCCGACTCCGTGGCCAACAAGCTGGGCAGCTT
CAGCAAGACGCTGGGCATCAAGCTGAAGAAAAACATGGGCGGCCTCGGCGGCCTGGTGCACGGCAAGATGGGCCGCGCCAACTCCGCCAA
TGGCAAGAACGGGGACTCGGCCGAGCGGGGCAAGGAGAAGAAGGCCAAGTCGCGCAAGGGCAGCAAGGAGGAGTCTGGTGCGTCGGCCAG
CACGTCGCCGTCGGAAAAGACCACGCCGTCGCCCACAGACAAGGCAGCGGGCGCGTCGCCGGCGGAGAAGGGCGGTGGGCCGCGGGGCGA
CGCCTGGAAGTACAGCACGGATGTGAAGCTGAGCCTCAACATCCTGCGCGCCGCCATGCAGGGGGAGCGCAAGTTCATCTTCGCCGGCCT
GCTGCTCACCAGCCACCGGCACCAGTTCCACGAGGAGATGATCGGCTACTACCTGACGAGCGCGCAGGAGCGCTTCAGCGCCGAGCAGGA
GCAGCGGCGCCGCGACGCCGCTACTGCGGCCGCCGCTGCCGCCGCCGCCGCCGCCGCCACGGCCAAGCGGCCGCCGCGCAGACCGGAGAC
GGAGGGCGTGCCGGTCCCGGAGCGCGCCTCTCCGGGCCCACCCACGCAGCTGGTGCTCAAGCTCAAGGAGCGGCCGAGCCCCGGGCCCGC
GGCAGGGCGTGCGGCGCGGGCGGCGGCGGGCGGCACGGCCTCCCCGGGGGGAGGCGCGCGGCGTGCGAGCGCCAGCGGACCAGTGCCTGG
CCGCAGCCCCCCGGCGCCAGCGCGCCAGAGCGTCATCCACGTGCAGGCGTCGGGCGCGCGGGACGAGGCGTGCGCGCCGGCCGTGGGGGC
GCTGCGGCCGTGCGCCACGTACCCGCAGCAGAACCGCTCGCTGTCGTCGCAGAGCTACAGCCCGGCGCGCGCCGCCGCCCTGCGCACCGT
CAACACGGTCGAGTCGCTGGCGCGCGCGGTGCCCGGGGCCCTACCGGGCGCGGCGGGGACGGCGGGGGCGGCCGAGCACAAGTCGCAGAC
CTACACCAACGGCTTCGGCGCCCTGCGCGACGGCCTGGAGTTCGCCGACGCCGACGCGCCGACCGCGCGCTCGAACGGTGAGTGCGGCCG
TGGCGGCCCGGGGCCGGTGCAGCGGCGCTGCCAGCGCGAGAACTGTGCGTTCTACGGGCGCGCCGAGACCGAGCACTACTGCTCCTACTG
CTACCGCGAGGAGCTGCGGCGGCGGCGCGAGGCGCGCGGGGCCCGGCCCTGAGCGGCGCGGCGCGGCGCGGGCGGCGAGGTTCTACCTTC
GAGGATTTCTTTTCCATTGTGTCGGTGTCTTTTTTACATGCCCTGGTCCACCGGAAGGCCGGCGCCTCCTCTGTCAGTGCCGTGTACGTG

>89301_89301_2_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000337137_OTUD7A_chr15_31862400_ENST00000382902_length(amino acids)=1221AA_BP=338
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRND
EVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIGKNWDLTAALSDYEQLRQVHTA
NLPHVFNEGRGPKQPEREPQPGHKVERPCLQRQDDIAQEKRLSRGISHASSAIVSLARSHVASECNNEQFPLEMPIYTFQLPDLSVYSED
FRSFIERDLIEQATMVALEQAGRLNWWSTVCTSCKRLLPLATTGDGNCLLHAASLGMWGFHDRDLVLRKALYTMMRTGAEREALKRRWRW
QQTQQNKESGLVYTEEEWEREWTELLKLASSEPRTHFSKNGGTGGGVDNSEDPVYESLEEFHVFVLAHILRRPIVVVADTMLRDSGGEAF
APIPFGGIYLPLEVPPNRCHCSPLVLAYDQAHFSALVSMEQRDQQREQAVIPLTDSEHKLLPLHFAVDPGKDWEWGKDDNDNARLAHLIL
SLEAKLNLLHSYMNVTWIRIPSETRAPLAQPESPTASAGEDVQSLADSLDSDRDSVCSNSNSNNGKNGKDKEKEKQRKEKDKTRADSVAN
KLGSFSKTLGIKLKKNMGGLGGLVHGKMGRANSANGKNGDSAERGKEKKAKSRKGSKEESGASASTSPSEKTTPSPTDKAAGASPAEKGG
GPRGDAWKYSTDVKLSLNILRAAMQGERKFIFAGLLLTSHRHQFHEEMIGYYLTSAQERFSAEQEQRRRDAATAAAAAAAAAAATAKRPP
RRPETEGVPVPERASPGPPTQLVLKLKERPSPGPAAGRAARAAAGGTASPGGGARRASASGPVPGRSPPAPARQSVIHVQASGARDEACA
PAVGALRPCATYPQQNRSLSSQSYSPARAAALRTVNTVESLARAVPGALPGAAGTAGAAEHKSQTYTNGFGALRDGLEFADADAPTARSN

--------------------------------------------------------------
>89301_89301_3_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000355704_OTUD7A_chr15_31862400_ENST00000307050_length(transcript)=3685nt_BP=887nt
CCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGA
GGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGTTTGCTCAGGTC
CACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCAGCGATGCCTGGGACGC
TGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCAACCGTGTGCTGCGTAA
CCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAGAGCCGCCCTCACCCCC
CAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGAATTACGGAGGTTGAGCTGGTCCGGAAT
CCCTAAGCCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAA
ACAAAAAGAATATTTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGA
CATCCCTCGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCA
CCCAGCCAGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACATAGGCAAAAACTGGGA
CCTGACAGCCGCTCTGAGCGACTATGAGCAGCTCCGCCAGGTGCACACAGCCAATCTGCCACATGTGTTCAATGAAGGGCGGGGTCCCAA
GCAGCCAGAGCGAGAGCCACAGCCCGGGCACAAGGTGGAGCGACCCTGCCTGCAGAGGCAGGACGACATTGCCCAAGAAAAGCGGCTTTC
CCGGGGGATTTCCCACGCCAGCTCAGCCATCGTCTCCCTGGCCCGGTCCCACGTGGCAAGTGAATGCAACAACGAGCAGTTCCCCCTGGA
GATGCCAATCTACACATTCCAGTTGCCAGACCTGAGCGTGTACAGCGAGGATTTCAGGAGCTTCATCGAGCGGGACTTGATCGAGCAGGC
AACAATGGTGGCTTTGGAGCAGGCAGGTCGCCTGAACTGGTGGTCCACTGTGTGCACGAGCTGTAAACGGCTTCTTCCTCTGGCCACAAC
AGGGGATGGGAACTGCCTTTTACATGCTGCTTCACTGGGAATGTGGGGGTTTCACGACCGGGACCTGGTGTTACGGAAAGCTCTCTATAC
CATGATGAGGACGGGAGCTGAGAGGGAAGCCCTGAAGCGGAGGTGGAGGTGGCAGCAGACGCAGCAGAATAAGGAGGAGGAGTGGGAGCG
GGAGTGGACGGAGCTGCTGAAGCTGGCCTCCAGCGAGCCGCGCACACACTTCAGCAAGAATGGCGGCACGGGCGGGGGTGTGGACAACTC
TGAGGACCCCGTGTACGAGAGCCTGGAAGAGTTCCACGTTTTTGTCCTAGCCCATATATTAAGAAGGCCCATCGTTGTTGTGGCAGATAC
AATGTTAAGAGACTCAGGTGGAGAAGCGTTCGCACCCATCCCATTCGGAGGGATCTACCTGCCCTTGGAGGTCCCTCCCAACAGATGCCA
CTGCTCGCCTCTGGTTCTGGCCTATGATCAAGCCCATTTCTCTGCCCTTGTGTCCATGGAACAGAGAGACCAGCAAAGAGAACAAGCCGT
GATCCCCCTGACGGATTCTGAGCACAAGCTGCTGCCTCTGCACTTTGCAGTGGACCCTGGCAAGGACTGGGAGTGGGGGAAAGACGACAA
CGATAACGCCCGGCTGGCCCACCTTATCCTGTCGCTAGAAGCCAAGCTGAACCTTCTGCACAGCTACATGAACGTGACGTGGATCCGGAT
CCCCTCCGAGACACGGGCGCCCCTGGCACAGCCGGAGTCTCCCACGGCCTCGGCAGGGGAGGACGTGCAGTCCCTGGCCGACTCGCTGGA
CTCGGACCGCGATTCGGTGTGCAGCAATTCTAACAGCAATAACGGCAAGAACGGCAAGGACAAGGAGAAGGAGAAGCAGCGCAAGGAGAA
GGACAAGACGCGCGCCGACTCCGTGGCCAACAAGCTGGGCAGCTTCAGCAAGACGCTGGGCATCAAGCTGAAGAAAAACATGGGCGGCCT
CGGCGGCCTGGTGCACGGCAAGATGGGCCGCGCCAACTCCGCCAATGGCAAGAACGGGGACTCGGCCGAGCGGGGCAAGGAGAAGAAGGC
CAAGTCGCGCAAGGGCAGCAAGGAGGAGTCTGGTGCGTCGGCCAGCACGTCGCCGTCGGAAAAGACCACGCCGTCGCCCACAGACAAGGC
AGCGGGCGCGTCGCCGGCGGAGAAGGGCGGTGGGCCGCGGGGCGACGCCTGGAAGTACAGCACGGATGTGAAGCTGAGCCTCAACATCCT
GCGCGCCGCCATGCAGGGGGAGCGCAAGTTCATCTTCGCCGGCCTGCTGCTCACCAGCCACCGGCACCAGTTCCACGAGGAGATGATCGG
CTACTACCTGACGAGCGCGCAGGAGCGCTTCAGCGCCGAGCAGGAGCAGCGGCGCCGCGACGCCGCTACTGCGGCCGCCGCTGCCGCCGC
CGCCGCCGCCGCCACGGCCAAGCGGCCGCCGCGCAGACCGGAGACGGAGGGCGTGCCGGTCCCGGAGCGCGCCTCTCCGGGCCCACCCAC
GCAGCTGGTGCTCAAGCTCAAGGAGCGGCCGAGCCCCGGGCCCGCGGCAGGGCGTGCGGCGCGGGCGGCGGCGGGCGGCACGGCCTCCCC
GGGGGGAGGCGCGCGGCGTGCGAGCGCCAGCGGACCAGTGCCTGGCCGCAGCCCCCCGGCGCCAGCGCGCCAGAGCGTCATCCACGTGCA
GGCGTCGGGCGCGCGGGACGAGGCGTGCGCGCCGGCCGTGGGGGCGCTGCGGCCGTGCGCCACGTACCCGCAGCAGAACCGCTCGCTGTC
GTCGCAGAGCTACAGCCCGGCGCGCGCCGCCGCCCTGCGCACCGTCAACACGGTCGAGTCGCTGGCGCGCGCGGTGCCCGGGGCCCTACC
GGGCGCGGCGGGGACGGCGGGGGCGGCCGAGCACAAGTCGCAGACCTACACCAACGGCTTCGGCGCCCTGCGCGACGGCCTGGAGTTCGC
CGACGCCGACGCGCCGACCGCGCGCTCGAACGGTGAGTGCGGCCGTGGCGGCCCGGGGCCGGTGCAGCGGCGCTGCCAGCGCGAGAACTG
TGCGTTCTACGGGCGCGCCGAGACCGAGCACTACTGCTCCTACTGCTACCGCGAGGAGCTGCGGCGGCGGCGCGAGGCGCGCGGGGCCCG
GCCCTGAGCGGCGCGGCGCGGCGCGGGCGGCGAGGTTCTACCTTCGAGGATTTCTTTTCCATTGTGTCGGTGTCTTTTTTACATGCCCTG

>89301_89301_3_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000355704_OTUD7A_chr15_31862400_ENST00000307050_length(amino acids)=1136AA_BP=260
MASDGARKQFWKRSNSKLPGSLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLNSEVVMETANRVLRNHSQRQ
GRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYF
AFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIGKNWDLTAAL
SDYEQLRQVHTANLPHVFNEGRGPKQPEREPQPGHKVERPCLQRQDDIAQEKRLSRGISHASSAIVSLARSHVASECNNEQFPLEMPIYT
FQLPDLSVYSEDFRSFIERDLIEQATMVALEQAGRLNWWSTVCTSCKRLLPLATTGDGNCLLHAASLGMWGFHDRDLVLRKALYTMMRTG
AEREALKRRWRWQQTQQNKEEEWEREWTELLKLASSEPRTHFSKNGGTGGGVDNSEDPVYESLEEFHVFVLAHILRRPIVVVADTMLRDS
GGEAFAPIPFGGIYLPLEVPPNRCHCSPLVLAYDQAHFSALVSMEQRDQQREQAVIPLTDSEHKLLPLHFAVDPGKDWEWGKDDNDNARL
AHLILSLEAKLNLLHSYMNVTWIRIPSETRAPLAQPESPTASAGEDVQSLADSLDSDRDSVCSNSNSNNGKNGKDKEKEKQRKEKDKTRA
DSVANKLGSFSKTLGIKLKKNMGGLGGLVHGKMGRANSANGKNGDSAERGKEKKAKSRKGSKEESGASASTSPSEKTTPSPTDKAAGASP
AEKGGGPRGDAWKYSTDVKLSLNILRAAMQGERKFIFAGLLLTSHRHQFHEEMIGYYLTSAQERFSAEQEQRRRDAATAAAAAAAAAAAT
AKRPPRRPETEGVPVPERASPGPPTQLVLKLKERPSPGPAAGRAARAAAGGTASPGGGARRASASGPVPGRSPPAPARQSVIHVQASGAR
DEACAPAVGALRPCATYPQQNRSLSSQSYSPARAAALRTVNTVESLARAVPGALPGAAGTAGAAEHKSQTYTNGFGALRDGLEFADADAP

--------------------------------------------------------------
>89301_89301_4_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000355704_OTUD7A_chr15_31862400_ENST00000382902_length(transcript)=3706nt_BP=887nt
CCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGA
GGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGTTTGCTCAGGTC
CACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCAGCGATGCCTGGGACGC
TGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCAACCGTGTGCTGCGTAA
CCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAGAGCCGCCCTCACCCCC
CAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGAATTACGGAGGTTGAGCTGGTCCGGAAT
CCCTAAGCCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAA
ACAAAAAGAATATTTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGA
CATCCCTCGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCA
CCCAGCCAGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACATAGGCAAAAACTGGGA
CCTGACAGCCGCTCTGAGCGACTATGAGCAGCTCCGCCAGGTGCACACAGCCAATCTGCCACATGTGTTCAATGAAGGGCGGGGTCCCAA
GCAGCCAGAGCGAGAGCCACAGCCCGGGCACAAGGTGGAGCGACCCTGCCTGCAGAGGCAGGACGACATTGCCCAAGAAAAGCGGCTTTC
CCGGGGGATTTCCCACGCCAGCTCAGCCATCGTCTCCCTGGCCCGGTCCCACGTGGCAAGTGAATGCAACAACGAGCAGTTCCCCCTGGA
GATGCCAATCTACACATTCCAGTTGCCAGACCTGAGCGTGTACAGCGAGGATTTCAGGAGCTTCATCGAGCGGGACTTGATCGAGCAGGC
AACAATGGTGGCTTTGGAGCAGGCAGGTCGCCTGAACTGGTGGTCCACTGTGTGCACGAGCTGTAAACGGCTTCTTCCTCTGGCCACAAC
AGGGGATGGGAACTGCCTTTTACATGCTGCTTCACTGGGAATGTGGGGGTTTCACGACCGGGACCTGGTGTTACGGAAAGCTCTCTATAC
CATGATGAGGACGGGAGCTGAGAGGGAAGCCCTGAAGCGGAGGTGGAGGTGGCAGCAGACGCAGCAGAATAAGGAGTCAGGGCTGGTGTA
CACAGAGGAGGAGTGGGAGCGGGAGTGGACGGAGCTGCTGAAGCTGGCCTCCAGCGAGCCGCGCACACACTTCAGCAAGAATGGCGGCAC
GGGCGGGGGTGTGGACAACTCTGAGGACCCCGTGTACGAGAGCCTGGAAGAGTTCCACGTTTTTGTCCTAGCCCATATATTAAGAAGGCC
CATCGTTGTTGTGGCAGATACAATGTTAAGAGACTCAGGTGGAGAAGCGTTCGCACCCATCCCATTCGGAGGGATCTACCTGCCCTTGGA
GGTCCCTCCCAACAGATGCCACTGCTCGCCTCTGGTTCTGGCCTATGATCAAGCCCATTTCTCTGCCCTTGTGTCCATGGAACAGAGAGA
CCAGCAAAGAGAACAAGCCGTGATCCCCCTGACGGATTCTGAGCACAAGCTGCTGCCTCTGCACTTTGCAGTGGACCCTGGCAAGGACTG
GGAGTGGGGGAAAGACGACAACGATAACGCCCGGCTGGCCCACCTTATCCTGTCGCTAGAAGCCAAGCTGAACCTTCTGCACAGCTACAT
GAACGTGACGTGGATCCGGATCCCCTCCGAGACACGGGCGCCCCTGGCACAGCCGGAGTCTCCCACGGCCTCGGCAGGGGAGGACGTGCA
GTCCCTGGCCGACTCGCTGGACTCGGACCGCGATTCGGTGTGCAGCAATTCTAACAGCAATAACGGCAAGAACGGCAAGGACAAGGAGAA
GGAGAAGCAGCGCAAGGAGAAGGACAAGACGCGCGCCGACTCCGTGGCCAACAAGCTGGGCAGCTTCAGCAAGACGCTGGGCATCAAGCT
GAAGAAAAACATGGGCGGCCTCGGCGGCCTGGTGCACGGCAAGATGGGCCGCGCCAACTCCGCCAATGGCAAGAACGGGGACTCGGCCGA
GCGGGGCAAGGAGAAGAAGGCCAAGTCGCGCAAGGGCAGCAAGGAGGAGTCTGGTGCGTCGGCCAGCACGTCGCCGTCGGAAAAGACCAC
GCCGTCGCCCACAGACAAGGCAGCGGGCGCGTCGCCGGCGGAGAAGGGCGGTGGGCCGCGGGGCGACGCCTGGAAGTACAGCACGGATGT
GAAGCTGAGCCTCAACATCCTGCGCGCCGCCATGCAGGGGGAGCGCAAGTTCATCTTCGCCGGCCTGCTGCTCACCAGCCACCGGCACCA
GTTCCACGAGGAGATGATCGGCTACTACCTGACGAGCGCGCAGGAGCGCTTCAGCGCCGAGCAGGAGCAGCGGCGCCGCGACGCCGCTAC
TGCGGCCGCCGCTGCCGCCGCCGCCGCCGCCGCCACGGCCAAGCGGCCGCCGCGCAGACCGGAGACGGAGGGCGTGCCGGTCCCGGAGCG
CGCCTCTCCGGGCCCACCCACGCAGCTGGTGCTCAAGCTCAAGGAGCGGCCGAGCCCCGGGCCCGCGGCAGGGCGTGCGGCGCGGGCGGC
GGCGGGCGGCACGGCCTCCCCGGGGGGAGGCGCGCGGCGTGCGAGCGCCAGCGGACCAGTGCCTGGCCGCAGCCCCCCGGCGCCAGCGCG
CCAGAGCGTCATCCACGTGCAGGCGTCGGGCGCGCGGGACGAGGCGTGCGCGCCGGCCGTGGGGGCGCTGCGGCCGTGCGCCACGTACCC
GCAGCAGAACCGCTCGCTGTCGTCGCAGAGCTACAGCCCGGCGCGCGCCGCCGCCCTGCGCACCGTCAACACGGTCGAGTCGCTGGCGCG
CGCGGTGCCCGGGGCCCTACCGGGCGCGGCGGGGACGGCGGGGGCGGCCGAGCACAAGTCGCAGACCTACACCAACGGCTTCGGCGCCCT
GCGCGACGGCCTGGAGTTCGCCGACGCCGACGCGCCGACCGCGCGCTCGAACGGTGAGTGCGGCCGTGGCGGCCCGGGGCCGGTGCAGCG
GCGCTGCCAGCGCGAGAACTGTGCGTTCTACGGGCGCGCCGAGACCGAGCACTACTGCTCCTACTGCTACCGCGAGGAGCTGCGGCGGCG
GCGCGAGGCGCGCGGGGCCCGGCCCTGAGCGGCGCGGCGCGGCGCGGGCGGCGAGGTTCTACCTTCGAGGATTTCTTTTCCATTGTGTCG
GTGTCTTTTTTACATGCCCTGGTCCACCGGAAGGCCGGCGCCTCCTCTGTCAGTGCCGTGTACGTGTTTGGTCAAACGTTCCTAATGGTG

>89301_89301_4_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000355704_OTUD7A_chr15_31862400_ENST00000382902_length(amino acids)=1143AA_BP=260
MASDGARKQFWKRSNSKLPGSLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLNSEVVMETANRVLRNHSQRQ
GRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYF
AFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIGKNWDLTAAL
SDYEQLRQVHTANLPHVFNEGRGPKQPEREPQPGHKVERPCLQRQDDIAQEKRLSRGISHASSAIVSLARSHVASECNNEQFPLEMPIYT
FQLPDLSVYSEDFRSFIERDLIEQATMVALEQAGRLNWWSTVCTSCKRLLPLATTGDGNCLLHAASLGMWGFHDRDLVLRKALYTMMRTG
AEREALKRRWRWQQTQQNKESGLVYTEEEWEREWTELLKLASSEPRTHFSKNGGTGGGVDNSEDPVYESLEEFHVFVLAHILRRPIVVVA
DTMLRDSGGEAFAPIPFGGIYLPLEVPPNRCHCSPLVLAYDQAHFSALVSMEQRDQQREQAVIPLTDSEHKLLPLHFAVDPGKDWEWGKD
DNDNARLAHLILSLEAKLNLLHSYMNVTWIRIPSETRAPLAQPESPTASAGEDVQSLADSLDSDRDSVCSNSNSNNGKNGKDKEKEKQRK
EKDKTRADSVANKLGSFSKTLGIKLKKNMGGLGGLVHGKMGRANSANGKNGDSAERGKEKKAKSRKGSKEESGASASTSPSEKTTPSPTD
KAAGASPAEKGGGPRGDAWKYSTDVKLSLNILRAAMQGERKFIFAGLLLTSHRHQFHEEMIGYYLTSAQERFSAEQEQRRRDAATAAAAA
AAAAAATAKRPPRRPETEGVPVPERASPGPPTQLVLKLKERPSPGPAAGRAARAAAGGTASPGGGARRASASGPVPGRSPPAPARQSVIH
VQASGARDEACAPAVGALRPCATYPQQNRSLSSQSYSPARAAALRTVNTVESLARAVPGALPGAAGTAGAAEHKSQTYTNGFGALRDGLE

--------------------------------------------------------------
>89301_89301_5_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000380995_OTUD7A_chr15_31862400_ENST00000307050_length(transcript)=3968nt_BP=1170nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGATG
CCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTCAG
CGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGAGGAATTACGGAGGTTGA
GCTGGTCCGGAATCCCTAAGCCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGCCA
CTCTCCAGAGAAAACAAAAAGAATATTTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAGGC
AGATCCACATAGACATCCCTCGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCATAT
GGGCGATCCGCCACCCAGCCAGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACATAG
GCAAAAACTGGGACCTGACAGCCGCTCTGAGCGACTATGAGCAGCTCCGCCAGGTGCACACAGCCAATCTGCCACATGTGTTCAATGAAG
GGCGGGGTCCCAAGCAGCCAGAGCGAGAGCCACAGCCCGGGCACAAGGTGGAGCGACCCTGCCTGCAGAGGCAGGACGACATTGCCCAAG
AAAAGCGGCTTTCCCGGGGGATTTCCCACGCCAGCTCAGCCATCGTCTCCCTGGCCCGGTCCCACGTGGCAAGTGAATGCAACAACGAGC
AGTTCCCCCTGGAGATGCCAATCTACACATTCCAGTTGCCAGACCTGAGCGTGTACAGCGAGGATTTCAGGAGCTTCATCGAGCGGGACT
TGATCGAGCAGGCAACAATGGTGGCTTTGGAGCAGGCAGGTCGCCTGAACTGGTGGTCCACTGTGTGCACGAGCTGTAAACGGCTTCTTC
CTCTGGCCACAACAGGGGATGGGAACTGCCTTTTACATGCTGCTTCACTGGGAATGTGGGGGTTTCACGACCGGGACCTGGTGTTACGGA
AAGCTCTCTATACCATGATGAGGACGGGAGCTGAGAGGGAAGCCCTGAAGCGGAGGTGGAGGTGGCAGCAGACGCAGCAGAATAAGGAGG
AGGAGTGGGAGCGGGAGTGGACGGAGCTGCTGAAGCTGGCCTCCAGCGAGCCGCGCACACACTTCAGCAAGAATGGCGGCACGGGCGGGG
GTGTGGACAACTCTGAGGACCCCGTGTACGAGAGCCTGGAAGAGTTCCACGTTTTTGTCCTAGCCCATATATTAAGAAGGCCCATCGTTG
TTGTGGCAGATACAATGTTAAGAGACTCAGGTGGAGAAGCGTTCGCACCCATCCCATTCGGAGGGATCTACCTGCCCTTGGAGGTCCCTC
CCAACAGATGCCACTGCTCGCCTCTGGTTCTGGCCTATGATCAAGCCCATTTCTCTGCCCTTGTGTCCATGGAACAGAGAGACCAGCAAA
GAGAACAAGCCGTGATCCCCCTGACGGATTCTGAGCACAAGCTGCTGCCTCTGCACTTTGCAGTGGACCCTGGCAAGGACTGGGAGTGGG
GGAAAGACGACAACGATAACGCCCGGCTGGCCCACCTTATCCTGTCGCTAGAAGCCAAGCTGAACCTTCTGCACAGCTACATGAACGTGA
CGTGGATCCGGATCCCCTCCGAGACACGGGCGCCCCTGGCACAGCCGGAGTCTCCCACGGCCTCGGCAGGGGAGGACGTGCAGTCCCTGG
CCGACTCGCTGGACTCGGACCGCGATTCGGTGTGCAGCAATTCTAACAGCAATAACGGCAAGAACGGCAAGGACAAGGAGAAGGAGAAGC
AGCGCAAGGAGAAGGACAAGACGCGCGCCGACTCCGTGGCCAACAAGCTGGGCAGCTTCAGCAAGACGCTGGGCATCAAGCTGAAGAAAA
ACATGGGCGGCCTCGGCGGCCTGGTGCACGGCAAGATGGGCCGCGCCAACTCCGCCAATGGCAAGAACGGGGACTCGGCCGAGCGGGGCA
AGGAGAAGAAGGCCAAGTCGCGCAAGGGCAGCAAGGAGGAGTCTGGTGCGTCGGCCAGCACGTCGCCGTCGGAAAAGACCACGCCGTCGC
CCACAGACAAGGCAGCGGGCGCGTCGCCGGCGGAGAAGGGCGGTGGGCCGCGGGGCGACGCCTGGAAGTACAGCACGGATGTGAAGCTGA
GCCTCAACATCCTGCGCGCCGCCATGCAGGGGGAGCGCAAGTTCATCTTCGCCGGCCTGCTGCTCACCAGCCACCGGCACCAGTTCCACG
AGGAGATGATCGGCTACTACCTGACGAGCGCGCAGGAGCGCTTCAGCGCCGAGCAGGAGCAGCGGCGCCGCGACGCCGCTACTGCGGCCG
CCGCTGCCGCCGCCGCCGCCGCCGCCACGGCCAAGCGGCCGCCGCGCAGACCGGAGACGGAGGGCGTGCCGGTCCCGGAGCGCGCCTCTC
CGGGCCCACCCACGCAGCTGGTGCTCAAGCTCAAGGAGCGGCCGAGCCCCGGGCCCGCGGCAGGGCGTGCGGCGCGGGCGGCGGCGGGCG
GCACGGCCTCCCCGGGGGGAGGCGCGCGGCGTGCGAGCGCCAGCGGACCAGTGCCTGGCCGCAGCCCCCCGGCGCCAGCGCGCCAGAGCG
TCATCCACGTGCAGGCGTCGGGCGCGCGGGACGAGGCGTGCGCGCCGGCCGTGGGGGCGCTGCGGCCGTGCGCCACGTACCCGCAGCAGA
ACCGCTCGCTGTCGTCGCAGAGCTACAGCCCGGCGCGCGCCGCCGCCCTGCGCACCGTCAACACGGTCGAGTCGCTGGCGCGCGCGGTGC
CCGGGGCCCTACCGGGCGCGGCGGGGACGGCGGGGGCGGCCGAGCACAAGTCGCAGACCTACACCAACGGCTTCGGCGCCCTGCGCGACG
GCCTGGAGTTCGCCGACGCCGACGCGCCGACCGCGCGCTCGAACGGTGAGTGCGGCCGTGGCGGCCCGGGGCCGGTGCAGCGGCGCTGCC
AGCGCGAGAACTGTGCGTTCTACGGGCGCGCCGAGACCGAGCACTACTGCTCCTACTGCTACCGCGAGGAGCTGCGGCGGCGGCGCGAGG
CGCGCGGGGCCCGGCCCTGAGCGGCGCGGCGCGGCGCGGGCGGCGAGGTTCTACCTTCGAGGATTTCTTTTCCATTGTGTCGGTGTCTTT
TTTACATGCCCTGGTCCACCGGAAGGCCGGCGCCTCCTCTGTCAGTGCCGTGTACGTGTTTGGTCAAACGTTCCTAATGGTGCCTGAACC

>89301_89301_5_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000380995_OTUD7A_chr15_31862400_ENST00000307050_length(amino acids)=1214AA_BP=338
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRND
EVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIGKNWDLTAALSDYEQLRQVHTA
NLPHVFNEGRGPKQPEREPQPGHKVERPCLQRQDDIAQEKRLSRGISHASSAIVSLARSHVASECNNEQFPLEMPIYTFQLPDLSVYSED
FRSFIERDLIEQATMVALEQAGRLNWWSTVCTSCKRLLPLATTGDGNCLLHAASLGMWGFHDRDLVLRKALYTMMRTGAEREALKRRWRW
QQTQQNKEEEWEREWTELLKLASSEPRTHFSKNGGTGGGVDNSEDPVYESLEEFHVFVLAHILRRPIVVVADTMLRDSGGEAFAPIPFGG
IYLPLEVPPNRCHCSPLVLAYDQAHFSALVSMEQRDQQREQAVIPLTDSEHKLLPLHFAVDPGKDWEWGKDDNDNARLAHLILSLEAKLN
LLHSYMNVTWIRIPSETRAPLAQPESPTASAGEDVQSLADSLDSDRDSVCSNSNSNNGKNGKDKEKEKQRKEKDKTRADSVANKLGSFSK
TLGIKLKKNMGGLGGLVHGKMGRANSANGKNGDSAERGKEKKAKSRKGSKEESGASASTSPSEKTTPSPTDKAAGASPAEKGGGPRGDAW
KYSTDVKLSLNILRAAMQGERKFIFAGLLLTSHRHQFHEEMIGYYLTSAQERFSAEQEQRRRDAATAAAAAAAAAAATAKRPPRRPETEG
VPVPERASPGPPTQLVLKLKERPSPGPAAGRAARAAAGGTASPGGGARRASASGPVPGRSPPAPARQSVIHVQASGARDEACAPAVGALR
PCATYPQQNRSLSSQSYSPARAAALRTVNTVESLARAVPGALPGAAGTAGAAEHKSQTYTNGFGALRDGLEFADADAPTARSNGECGRGG

--------------------------------------------------------------
>89301_89301_6_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000380995_OTUD7A_chr15_31862400_ENST00000382902_length(transcript)=3989nt_BP=1170nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGATG
CCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTCAG
CGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGAGGAATTACGGAGGTTGA
GCTGGTCCGGAATCCCTAAGCCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGCCA
CTCTCCAGAGAAAACAAAAAGAATATTTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAGGC
AGATCCACATAGACATCCCTCGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCATAT
GGGCGATCCGCCACCCAGCCAGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACATAG
GCAAAAACTGGGACCTGACAGCCGCTCTGAGCGACTATGAGCAGCTCCGCCAGGTGCACACAGCCAATCTGCCACATGTGTTCAATGAAG
GGCGGGGTCCCAAGCAGCCAGAGCGAGAGCCACAGCCCGGGCACAAGGTGGAGCGACCCTGCCTGCAGAGGCAGGACGACATTGCCCAAG
AAAAGCGGCTTTCCCGGGGGATTTCCCACGCCAGCTCAGCCATCGTCTCCCTGGCCCGGTCCCACGTGGCAAGTGAATGCAACAACGAGC
AGTTCCCCCTGGAGATGCCAATCTACACATTCCAGTTGCCAGACCTGAGCGTGTACAGCGAGGATTTCAGGAGCTTCATCGAGCGGGACT
TGATCGAGCAGGCAACAATGGTGGCTTTGGAGCAGGCAGGTCGCCTGAACTGGTGGTCCACTGTGTGCACGAGCTGTAAACGGCTTCTTC
CTCTGGCCACAACAGGGGATGGGAACTGCCTTTTACATGCTGCTTCACTGGGAATGTGGGGGTTTCACGACCGGGACCTGGTGTTACGGA
AAGCTCTCTATACCATGATGAGGACGGGAGCTGAGAGGGAAGCCCTGAAGCGGAGGTGGAGGTGGCAGCAGACGCAGCAGAATAAGGAGT
CAGGGCTGGTGTACACAGAGGAGGAGTGGGAGCGGGAGTGGACGGAGCTGCTGAAGCTGGCCTCCAGCGAGCCGCGCACACACTTCAGCA
AGAATGGCGGCACGGGCGGGGGTGTGGACAACTCTGAGGACCCCGTGTACGAGAGCCTGGAAGAGTTCCACGTTTTTGTCCTAGCCCATA
TATTAAGAAGGCCCATCGTTGTTGTGGCAGATACAATGTTAAGAGACTCAGGTGGAGAAGCGTTCGCACCCATCCCATTCGGAGGGATCT
ACCTGCCCTTGGAGGTCCCTCCCAACAGATGCCACTGCTCGCCTCTGGTTCTGGCCTATGATCAAGCCCATTTCTCTGCCCTTGTGTCCA
TGGAACAGAGAGACCAGCAAAGAGAACAAGCCGTGATCCCCCTGACGGATTCTGAGCACAAGCTGCTGCCTCTGCACTTTGCAGTGGACC
CTGGCAAGGACTGGGAGTGGGGGAAAGACGACAACGATAACGCCCGGCTGGCCCACCTTATCCTGTCGCTAGAAGCCAAGCTGAACCTTC
TGCACAGCTACATGAACGTGACGTGGATCCGGATCCCCTCCGAGACACGGGCGCCCCTGGCACAGCCGGAGTCTCCCACGGCCTCGGCAG
GGGAGGACGTGCAGTCCCTGGCCGACTCGCTGGACTCGGACCGCGATTCGGTGTGCAGCAATTCTAACAGCAATAACGGCAAGAACGGCA
AGGACAAGGAGAAGGAGAAGCAGCGCAAGGAGAAGGACAAGACGCGCGCCGACTCCGTGGCCAACAAGCTGGGCAGCTTCAGCAAGACGC
TGGGCATCAAGCTGAAGAAAAACATGGGCGGCCTCGGCGGCCTGGTGCACGGCAAGATGGGCCGCGCCAACTCCGCCAATGGCAAGAACG
GGGACTCGGCCGAGCGGGGCAAGGAGAAGAAGGCCAAGTCGCGCAAGGGCAGCAAGGAGGAGTCTGGTGCGTCGGCCAGCACGTCGCCGT
CGGAAAAGACCACGCCGTCGCCCACAGACAAGGCAGCGGGCGCGTCGCCGGCGGAGAAGGGCGGTGGGCCGCGGGGCGACGCCTGGAAGT
ACAGCACGGATGTGAAGCTGAGCCTCAACATCCTGCGCGCCGCCATGCAGGGGGAGCGCAAGTTCATCTTCGCCGGCCTGCTGCTCACCA
GCCACCGGCACCAGTTCCACGAGGAGATGATCGGCTACTACCTGACGAGCGCGCAGGAGCGCTTCAGCGCCGAGCAGGAGCAGCGGCGCC
GCGACGCCGCTACTGCGGCCGCCGCTGCCGCCGCCGCCGCCGCCGCCACGGCCAAGCGGCCGCCGCGCAGACCGGAGACGGAGGGCGTGC
CGGTCCCGGAGCGCGCCTCTCCGGGCCCACCCACGCAGCTGGTGCTCAAGCTCAAGGAGCGGCCGAGCCCCGGGCCCGCGGCAGGGCGTG
CGGCGCGGGCGGCGGCGGGCGGCACGGCCTCCCCGGGGGGAGGCGCGCGGCGTGCGAGCGCCAGCGGACCAGTGCCTGGCCGCAGCCCCC
CGGCGCCAGCGCGCCAGAGCGTCATCCACGTGCAGGCGTCGGGCGCGCGGGACGAGGCGTGCGCGCCGGCCGTGGGGGCGCTGCGGCCGT
GCGCCACGTACCCGCAGCAGAACCGCTCGCTGTCGTCGCAGAGCTACAGCCCGGCGCGCGCCGCCGCCCTGCGCACCGTCAACACGGTCG
AGTCGCTGGCGCGCGCGGTGCCCGGGGCCCTACCGGGCGCGGCGGGGACGGCGGGGGCGGCCGAGCACAAGTCGCAGACCTACACCAACG
GCTTCGGCGCCCTGCGCGACGGCCTGGAGTTCGCCGACGCCGACGCGCCGACCGCGCGCTCGAACGGTGAGTGCGGCCGTGGCGGCCCGG
GGCCGGTGCAGCGGCGCTGCCAGCGCGAGAACTGTGCGTTCTACGGGCGCGCCGAGACCGAGCACTACTGCTCCTACTGCTACCGCGAGG
AGCTGCGGCGGCGGCGCGAGGCGCGCGGGGCCCGGCCCTGAGCGGCGCGGCGCGGCGCGGGCGGCGAGGTTCTACCTTCGAGGATTTCTT
TTCCATTGTGTCGGTGTCTTTTTTACATGCCCTGGTCCACCGGAAGGCCGGCGCCTCCTCTGTCAGTGCCGTGTACGTGTTTGGTCAAAC

>89301_89301_6_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000380995_OTUD7A_chr15_31862400_ENST00000382902_length(amino acids)=1221AA_BP=338
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRND
EVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIGKNWDLTAALSDYEQLRQVHTA
NLPHVFNEGRGPKQPEREPQPGHKVERPCLQRQDDIAQEKRLSRGISHASSAIVSLARSHVASECNNEQFPLEMPIYTFQLPDLSVYSED
FRSFIERDLIEQATMVALEQAGRLNWWSTVCTSCKRLLPLATTGDGNCLLHAASLGMWGFHDRDLVLRKALYTMMRTGAEREALKRRWRW
QQTQQNKESGLVYTEEEWEREWTELLKLASSEPRTHFSKNGGTGGGVDNSEDPVYESLEEFHVFVLAHILRRPIVVVADTMLRDSGGEAF
APIPFGGIYLPLEVPPNRCHCSPLVLAYDQAHFSALVSMEQRDQQREQAVIPLTDSEHKLLPLHFAVDPGKDWEWGKDDNDNARLAHLIL
SLEAKLNLLHSYMNVTWIRIPSETRAPLAQPESPTASAGEDVQSLADSLDSDRDSVCSNSNSNNGKNGKDKEKEKQRKEKDKTRADSVAN
KLGSFSKTLGIKLKKNMGGLGGLVHGKMGRANSANGKNGDSAERGKEKKAKSRKGSKEESGASASTSPSEKTTPSPTDKAAGASPAEKGG
GPRGDAWKYSTDVKLSLNILRAAMQGERKFIFAGLLLTSHRHQFHEEMIGYYLTSAQERFSAEQEQRRRDAATAAAAAAAAAAATAKRPP
RRPETEGVPVPERASPGPPTQLVLKLKERPSPGPAAGRAARAAAGGTASPGGGARRASASGPVPGRSPPAPARQSVIHVQASGARDEACA
PAVGALRPCATYPQQNRSLSSQSYSPARAAALRTVNTVESLARAVPGALPGAAGTAGAAEHKSQTYTNGFGALRDGLEFADADAPTARSN

--------------------------------------------------------------
>89301_89301_7_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000406733_OTUD7A_chr15_31862400_ENST00000307050_length(transcript)=4060nt_BP=1262nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGA
TGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTC
AGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGAGGAATTACGGAGGTT
GAGCTGGTCCGGAATCCCTAAGCCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGC
CACTCTCCAGAGAAAACAAAAAGAATATTTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAG
GCAGATCCACATAGACATCCCTCGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCAT
ATGGGCGATCCGCCACCCAGCCAGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACAT
AGGCAAAAACTGGGACCTGACAGCCGCTCTGAGCGACTATGAGCAGCTCCGCCAGGTGCACACAGCCAATCTGCCACATGTGTTCAATGA
AGGGCGGGGTCCCAAGCAGCCAGAGCGAGAGCCACAGCCCGGGCACAAGGTGGAGCGACCCTGCCTGCAGAGGCAGGACGACATTGCCCA
AGAAAAGCGGCTTTCCCGGGGGATTTCCCACGCCAGCTCAGCCATCGTCTCCCTGGCCCGGTCCCACGTGGCAAGTGAATGCAACAACGA
GCAGTTCCCCCTGGAGATGCCAATCTACACATTCCAGTTGCCAGACCTGAGCGTGTACAGCGAGGATTTCAGGAGCTTCATCGAGCGGGA
CTTGATCGAGCAGGCAACAATGGTGGCTTTGGAGCAGGCAGGTCGCCTGAACTGGTGGTCCACTGTGTGCACGAGCTGTAAACGGCTTCT
TCCTCTGGCCACAACAGGGGATGGGAACTGCCTTTTACATGCTGCTTCACTGGGAATGTGGGGGTTTCACGACCGGGACCTGGTGTTACG
GAAAGCTCTCTATACCATGATGAGGACGGGAGCTGAGAGGGAAGCCCTGAAGCGGAGGTGGAGGTGGCAGCAGACGCAGCAGAATAAGGA
GGAGGAGTGGGAGCGGGAGTGGACGGAGCTGCTGAAGCTGGCCTCCAGCGAGCCGCGCACACACTTCAGCAAGAATGGCGGCACGGGCGG
GGGTGTGGACAACTCTGAGGACCCCGTGTACGAGAGCCTGGAAGAGTTCCACGTTTTTGTCCTAGCCCATATATTAAGAAGGCCCATCGT
TGTTGTGGCAGATACAATGTTAAGAGACTCAGGTGGAGAAGCGTTCGCACCCATCCCATTCGGAGGGATCTACCTGCCCTTGGAGGTCCC
TCCCAACAGATGCCACTGCTCGCCTCTGGTTCTGGCCTATGATCAAGCCCATTTCTCTGCCCTTGTGTCCATGGAACAGAGAGACCAGCA
AAGAGAACAAGCCGTGATCCCCCTGACGGATTCTGAGCACAAGCTGCTGCCTCTGCACTTTGCAGTGGACCCTGGCAAGGACTGGGAGTG
GGGGAAAGACGACAACGATAACGCCCGGCTGGCCCACCTTATCCTGTCGCTAGAAGCCAAGCTGAACCTTCTGCACAGCTACATGAACGT
GACGTGGATCCGGATCCCCTCCGAGACACGGGCGCCCCTGGCACAGCCGGAGTCTCCCACGGCCTCGGCAGGGGAGGACGTGCAGTCCCT
GGCCGACTCGCTGGACTCGGACCGCGATTCGGTGTGCAGCAATTCTAACAGCAATAACGGCAAGAACGGCAAGGACAAGGAGAAGGAGAA
GCAGCGCAAGGAGAAGGACAAGACGCGCGCCGACTCCGTGGCCAACAAGCTGGGCAGCTTCAGCAAGACGCTGGGCATCAAGCTGAAGAA
AAACATGGGCGGCCTCGGCGGCCTGGTGCACGGCAAGATGGGCCGCGCCAACTCCGCCAATGGCAAGAACGGGGACTCGGCCGAGCGGGG
CAAGGAGAAGAAGGCCAAGTCGCGCAAGGGCAGCAAGGAGGAGTCTGGTGCGTCGGCCAGCACGTCGCCGTCGGAAAAGACCACGCCGTC
GCCCACAGACAAGGCAGCGGGCGCGTCGCCGGCGGAGAAGGGCGGTGGGCCGCGGGGCGACGCCTGGAAGTACAGCACGGATGTGAAGCT
GAGCCTCAACATCCTGCGCGCCGCCATGCAGGGGGAGCGCAAGTTCATCTTCGCCGGCCTGCTGCTCACCAGCCACCGGCACCAGTTCCA
CGAGGAGATGATCGGCTACTACCTGACGAGCGCGCAGGAGCGCTTCAGCGCCGAGCAGGAGCAGCGGCGCCGCGACGCCGCTACTGCGGC
CGCCGCTGCCGCCGCCGCCGCCGCCGCCACGGCCAAGCGGCCGCCGCGCAGACCGGAGACGGAGGGCGTGCCGGTCCCGGAGCGCGCCTC
TCCGGGCCCACCCACGCAGCTGGTGCTCAAGCTCAAGGAGCGGCCGAGCCCCGGGCCCGCGGCAGGGCGTGCGGCGCGGGCGGCGGCGGG
CGGCACGGCCTCCCCGGGGGGAGGCGCGCGGCGTGCGAGCGCCAGCGGACCAGTGCCTGGCCGCAGCCCCCCGGCGCCAGCGCGCCAGAG
CGTCATCCACGTGCAGGCGTCGGGCGCGCGGGACGAGGCGTGCGCGCCGGCCGTGGGGGCGCTGCGGCCGTGCGCCACGTACCCGCAGCA
GAACCGCTCGCTGTCGTCGCAGAGCTACAGCCCGGCGCGCGCCGCCGCCCTGCGCACCGTCAACACGGTCGAGTCGCTGGCGCGCGCGGT
GCCCGGGGCCCTACCGGGCGCGGCGGGGACGGCGGGGGCGGCCGAGCACAAGTCGCAGACCTACACCAACGGCTTCGGCGCCCTGCGCGA
CGGCCTGGAGTTCGCCGACGCCGACGCGCCGACCGCGCGCTCGAACGGTGAGTGCGGCCGTGGCGGCCCGGGGCCGGTGCAGCGGCGCTG
CCAGCGCGAGAACTGTGCGTTCTACGGGCGCGCCGAGACCGAGCACTACTGCTCCTACTGCTACCGCGAGGAGCTGCGGCGGCGGCGCGA
GGCGCGCGGGGCCCGGCCCTGAGCGGCGCGGCGCGGCGCGGGCGGCGAGGTTCTACCTTCGAGGATTTCTTTTCCATTGTGTCGGTGTCT
TTTTTACATGCCCTGGTCCACCGGAAGGCCGGCGCCTCCTCTGTCAGTGCCGTGTACGTGTTTGGTCAAACGTTCCTAATGGTGCCTGAA

>89301_89301_7_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000406733_OTUD7A_chr15_31862400_ENST00000307050_length(amino acids)=1216AA_BP=340
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGG
TSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSR
NDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIGKNWDLTAALSDYEQLRQVH
TANLPHVFNEGRGPKQPEREPQPGHKVERPCLQRQDDIAQEKRLSRGISHASSAIVSLARSHVASECNNEQFPLEMPIYTFQLPDLSVYS
EDFRSFIERDLIEQATMVALEQAGRLNWWSTVCTSCKRLLPLATTGDGNCLLHAASLGMWGFHDRDLVLRKALYTMMRTGAEREALKRRW
RWQQTQQNKEEEWEREWTELLKLASSEPRTHFSKNGGTGGGVDNSEDPVYESLEEFHVFVLAHILRRPIVVVADTMLRDSGGEAFAPIPF
GGIYLPLEVPPNRCHCSPLVLAYDQAHFSALVSMEQRDQQREQAVIPLTDSEHKLLPLHFAVDPGKDWEWGKDDNDNARLAHLILSLEAK
LNLLHSYMNVTWIRIPSETRAPLAQPESPTASAGEDVQSLADSLDSDRDSVCSNSNSNNGKNGKDKEKEKQRKEKDKTRADSVANKLGSF
SKTLGIKLKKNMGGLGGLVHGKMGRANSANGKNGDSAERGKEKKAKSRKGSKEESGASASTSPSEKTTPSPTDKAAGASPAEKGGGPRGD
AWKYSTDVKLSLNILRAAMQGERKFIFAGLLLTSHRHQFHEEMIGYYLTSAQERFSAEQEQRRRDAATAAAAAAAAAAATAKRPPRRPET
EGVPVPERASPGPPTQLVLKLKERPSPGPAAGRAARAAAGGTASPGGGARRASASGPVPGRSPPAPARQSVIHVQASGARDEACAPAVGA
LRPCATYPQQNRSLSSQSYSPARAAALRTVNTVESLARAVPGALPGAAGTAGAAEHKSQTYTNGFGALRDGLEFADADAPTARSNGECGR

--------------------------------------------------------------
>89301_89301_8_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000406733_OTUD7A_chr15_31862400_ENST00000382902_length(transcript)=4081nt_BP=1262nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGA
TGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTC
AGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGAGGAATTACGGAGGTT
GAGCTGGTCCGGAATCCCTAAGCCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGC
CACTCTCCAGAGAAAACAAAAAGAATATTTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAG
GCAGATCCACATAGACATCCCTCGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCAT
ATGGGCGATCCGCCACCCAGCCAGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACAT
AGGCAAAAACTGGGACCTGACAGCCGCTCTGAGCGACTATGAGCAGCTCCGCCAGGTGCACACAGCCAATCTGCCACATGTGTTCAATGA
AGGGCGGGGTCCCAAGCAGCCAGAGCGAGAGCCACAGCCCGGGCACAAGGTGGAGCGACCCTGCCTGCAGAGGCAGGACGACATTGCCCA
AGAAAAGCGGCTTTCCCGGGGGATTTCCCACGCCAGCTCAGCCATCGTCTCCCTGGCCCGGTCCCACGTGGCAAGTGAATGCAACAACGA
GCAGTTCCCCCTGGAGATGCCAATCTACACATTCCAGTTGCCAGACCTGAGCGTGTACAGCGAGGATTTCAGGAGCTTCATCGAGCGGGA
CTTGATCGAGCAGGCAACAATGGTGGCTTTGGAGCAGGCAGGTCGCCTGAACTGGTGGTCCACTGTGTGCACGAGCTGTAAACGGCTTCT
TCCTCTGGCCACAACAGGGGATGGGAACTGCCTTTTACATGCTGCTTCACTGGGAATGTGGGGGTTTCACGACCGGGACCTGGTGTTACG
GAAAGCTCTCTATACCATGATGAGGACGGGAGCTGAGAGGGAAGCCCTGAAGCGGAGGTGGAGGTGGCAGCAGACGCAGCAGAATAAGGA
GTCAGGGCTGGTGTACACAGAGGAGGAGTGGGAGCGGGAGTGGACGGAGCTGCTGAAGCTGGCCTCCAGCGAGCCGCGCACACACTTCAG
CAAGAATGGCGGCACGGGCGGGGGTGTGGACAACTCTGAGGACCCCGTGTACGAGAGCCTGGAAGAGTTCCACGTTTTTGTCCTAGCCCA
TATATTAAGAAGGCCCATCGTTGTTGTGGCAGATACAATGTTAAGAGACTCAGGTGGAGAAGCGTTCGCACCCATCCCATTCGGAGGGAT
CTACCTGCCCTTGGAGGTCCCTCCCAACAGATGCCACTGCTCGCCTCTGGTTCTGGCCTATGATCAAGCCCATTTCTCTGCCCTTGTGTC
CATGGAACAGAGAGACCAGCAAAGAGAACAAGCCGTGATCCCCCTGACGGATTCTGAGCACAAGCTGCTGCCTCTGCACTTTGCAGTGGA
CCCTGGCAAGGACTGGGAGTGGGGGAAAGACGACAACGATAACGCCCGGCTGGCCCACCTTATCCTGTCGCTAGAAGCCAAGCTGAACCT
TCTGCACAGCTACATGAACGTGACGTGGATCCGGATCCCCTCCGAGACACGGGCGCCCCTGGCACAGCCGGAGTCTCCCACGGCCTCGGC
AGGGGAGGACGTGCAGTCCCTGGCCGACTCGCTGGACTCGGACCGCGATTCGGTGTGCAGCAATTCTAACAGCAATAACGGCAAGAACGG
CAAGGACAAGGAGAAGGAGAAGCAGCGCAAGGAGAAGGACAAGACGCGCGCCGACTCCGTGGCCAACAAGCTGGGCAGCTTCAGCAAGAC
GCTGGGCATCAAGCTGAAGAAAAACATGGGCGGCCTCGGCGGCCTGGTGCACGGCAAGATGGGCCGCGCCAACTCCGCCAATGGCAAGAA
CGGGGACTCGGCCGAGCGGGGCAAGGAGAAGAAGGCCAAGTCGCGCAAGGGCAGCAAGGAGGAGTCTGGTGCGTCGGCCAGCACGTCGCC
GTCGGAAAAGACCACGCCGTCGCCCACAGACAAGGCAGCGGGCGCGTCGCCGGCGGAGAAGGGCGGTGGGCCGCGGGGCGACGCCTGGAA
GTACAGCACGGATGTGAAGCTGAGCCTCAACATCCTGCGCGCCGCCATGCAGGGGGAGCGCAAGTTCATCTTCGCCGGCCTGCTGCTCAC
CAGCCACCGGCACCAGTTCCACGAGGAGATGATCGGCTACTACCTGACGAGCGCGCAGGAGCGCTTCAGCGCCGAGCAGGAGCAGCGGCG
CCGCGACGCCGCTACTGCGGCCGCCGCTGCCGCCGCCGCCGCCGCCGCCACGGCCAAGCGGCCGCCGCGCAGACCGGAGACGGAGGGCGT
GCCGGTCCCGGAGCGCGCCTCTCCGGGCCCACCCACGCAGCTGGTGCTCAAGCTCAAGGAGCGGCCGAGCCCCGGGCCCGCGGCAGGGCG
TGCGGCGCGGGCGGCGGCGGGCGGCACGGCCTCCCCGGGGGGAGGCGCGCGGCGTGCGAGCGCCAGCGGACCAGTGCCTGGCCGCAGCCC
CCCGGCGCCAGCGCGCCAGAGCGTCATCCACGTGCAGGCGTCGGGCGCGCGGGACGAGGCGTGCGCGCCGGCCGTGGGGGCGCTGCGGCC
GTGCGCCACGTACCCGCAGCAGAACCGCTCGCTGTCGTCGCAGAGCTACAGCCCGGCGCGCGCCGCCGCCCTGCGCACCGTCAACACGGT
CGAGTCGCTGGCGCGCGCGGTGCCCGGGGCCCTACCGGGCGCGGCGGGGACGGCGGGGGCGGCCGAGCACAAGTCGCAGACCTACACCAA
CGGCTTCGGCGCCCTGCGCGACGGCCTGGAGTTCGCCGACGCCGACGCGCCGACCGCGCGCTCGAACGGTGAGTGCGGCCGTGGCGGCCC
GGGGCCGGTGCAGCGGCGCTGCCAGCGCGAGAACTGTGCGTTCTACGGGCGCGCCGAGACCGAGCACTACTGCTCCTACTGCTACCGCGA
GGAGCTGCGGCGGCGGCGCGAGGCGCGCGGGGCCCGGCCCTGAGCGGCGCGGCGCGGCGCGGGCGGCGAGGTTCTACCTTCGAGGATTTC
TTTTCCATTGTGTCGGTGTCTTTTTTACATGCCCTGGTCCACCGGAAGGCCGGCGCCTCCTCTGTCAGTGCCGTGTACGTGTTTGGTCAA

>89301_89301_8_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000406733_OTUD7A_chr15_31862400_ENST00000382902_length(amino acids)=1223AA_BP=340
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGG
TSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSR
NDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIGKNWDLTAALSDYEQLRQVH
TANLPHVFNEGRGPKQPEREPQPGHKVERPCLQRQDDIAQEKRLSRGISHASSAIVSLARSHVASECNNEQFPLEMPIYTFQLPDLSVYS
EDFRSFIERDLIEQATMVALEQAGRLNWWSTVCTSCKRLLPLATTGDGNCLLHAASLGMWGFHDRDLVLRKALYTMMRTGAEREALKRRW
RWQQTQQNKESGLVYTEEEWEREWTELLKLASSEPRTHFSKNGGTGGGVDNSEDPVYESLEEFHVFVLAHILRRPIVVVADTMLRDSGGE
AFAPIPFGGIYLPLEVPPNRCHCSPLVLAYDQAHFSALVSMEQRDQQREQAVIPLTDSEHKLLPLHFAVDPGKDWEWGKDDNDNARLAHL
ILSLEAKLNLLHSYMNVTWIRIPSETRAPLAQPESPTASAGEDVQSLADSLDSDRDSVCSNSNSNNGKNGKDKEKEKQRKEKDKTRADSV
ANKLGSFSKTLGIKLKKNMGGLGGLVHGKMGRANSANGKNGDSAERGKEKKAKSRKGSKEESGASASTSPSEKTTPSPTDKAAGASPAEK
GGGPRGDAWKYSTDVKLSLNILRAAMQGERKFIFAGLLLTSHRHQFHEEMIGYYLTSAQERFSAEQEQRRRDAATAAAAAAAAAAATAKR
PPRRPETEGVPVPERASPGPPTQLVLKLKERPSPGPAAGRAARAAAGGTASPGGGARRASASGPVPGRSPPAPARQSVIHVQASGARDEA
CAPAVGALRPCATYPQQNRSLSSQSYSPARAAALRTVNTVESLARAVPGALPGAAGTAGAAEHKSQTYTNGFGALRDGLEFADADAPTAR

--------------------------------------------------------------
>89301_89301_9_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000407381_OTUD7A_chr15_31862400_ENST00000307050_length(transcript)=3751nt_BP=953nt
CTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCG
CGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCAT
CCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACC
AGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCT
GGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCC
CACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAA
GTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGAATTACGGAGGTTGAGCTGGTCCGGAATCCCTAAGCCAGTGCGTCCAATGAC
GTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAAACAAAAAGAATATTTTGCATTTAT
TGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGACATCCCTCGCATGAGCCCTGAAGC
GTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCACCCAGCCAGTGGATACGTTCAGGG
TATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACATAGGCAAAAACTGGGACCTGACAGCCGCTCTGAGCGACTA
TGAGCAGCTCCGCCAGGTGCACACAGCCAATCTGCCACATGTGTTCAATGAAGGGCGGGGTCCCAAGCAGCCAGAGCGAGAGCCACAGCC
CGGGCACAAGGTGGAGCGACCCTGCCTGCAGAGGCAGGACGACATTGCCCAAGAAAAGCGGCTTTCCCGGGGGATTTCCCACGCCAGCTC
AGCCATCGTCTCCCTGGCCCGGTCCCACGTGGCAAGTGAATGCAACAACGAGCAGTTCCCCCTGGAGATGCCAATCTACACATTCCAGTT
GCCAGACCTGAGCGTGTACAGCGAGGATTTCAGGAGCTTCATCGAGCGGGACTTGATCGAGCAGGCAACAATGGTGGCTTTGGAGCAGGC
AGGTCGCCTGAACTGGTGGTCCACTGTGTGCACGAGCTGTAAACGGCTTCTTCCTCTGGCCACAACAGGGGATGGGAACTGCCTTTTACA
TGCTGCTTCACTGGGAATGTGGGGGTTTCACGACCGGGACCTGGTGTTACGGAAAGCTCTCTATACCATGATGAGGACGGGAGCTGAGAG
GGAAGCCCTGAAGCGGAGGTGGAGGTGGCAGCAGACGCAGCAGAATAAGGAGGAGGAGTGGGAGCGGGAGTGGACGGAGCTGCTGAAGCT
GGCCTCCAGCGAGCCGCGCACACACTTCAGCAAGAATGGCGGCACGGGCGGGGGTGTGGACAACTCTGAGGACCCCGTGTACGAGAGCCT
GGAAGAGTTCCACGTTTTTGTCCTAGCCCATATATTAAGAAGGCCCATCGTTGTTGTGGCAGATACAATGTTAAGAGACTCAGGTGGAGA
AGCGTTCGCACCCATCCCATTCGGAGGGATCTACCTGCCCTTGGAGGTCCCTCCCAACAGATGCCACTGCTCGCCTCTGGTTCTGGCCTA
TGATCAAGCCCATTTCTCTGCCCTTGTGTCCATGGAACAGAGAGACCAGCAAAGAGAACAAGCCGTGATCCCCCTGACGGATTCTGAGCA
CAAGCTGCTGCCTCTGCACTTTGCAGTGGACCCTGGCAAGGACTGGGAGTGGGGGAAAGACGACAACGATAACGCCCGGCTGGCCCACCT
TATCCTGTCGCTAGAAGCCAAGCTGAACCTTCTGCACAGCTACATGAACGTGACGTGGATCCGGATCCCCTCCGAGACACGGGCGCCCCT
GGCACAGCCGGAGTCTCCCACGGCCTCGGCAGGGGAGGACGTGCAGTCCCTGGCCGACTCGCTGGACTCGGACCGCGATTCGGTGTGCAG
CAATTCTAACAGCAATAACGGCAAGAACGGCAAGGACAAGGAGAAGGAGAAGCAGCGCAAGGAGAAGGACAAGACGCGCGCCGACTCCGT
GGCCAACAAGCTGGGCAGCTTCAGCAAGACGCTGGGCATCAAGCTGAAGAAAAACATGGGCGGCCTCGGCGGCCTGGTGCACGGCAAGAT
GGGCCGCGCCAACTCCGCCAATGGCAAGAACGGGGACTCGGCCGAGCGGGGCAAGGAGAAGAAGGCCAAGTCGCGCAAGGGCAGCAAGGA
GGAGTCTGGTGCGTCGGCCAGCACGTCGCCGTCGGAAAAGACCACGCCGTCGCCCACAGACAAGGCAGCGGGCGCGTCGCCGGCGGAGAA
GGGCGGTGGGCCGCGGGGCGACGCCTGGAAGTACAGCACGGATGTGAAGCTGAGCCTCAACATCCTGCGCGCCGCCATGCAGGGGGAGCG
CAAGTTCATCTTCGCCGGCCTGCTGCTCACCAGCCACCGGCACCAGTTCCACGAGGAGATGATCGGCTACTACCTGACGAGCGCGCAGGA
GCGCTTCAGCGCCGAGCAGGAGCAGCGGCGCCGCGACGCCGCTACTGCGGCCGCCGCTGCCGCCGCCGCCGCCGCCGCCACGGCCAAGCG
GCCGCCGCGCAGACCGGAGACGGAGGGCGTGCCGGTCCCGGAGCGCGCCTCTCCGGGCCCACCCACGCAGCTGGTGCTCAAGCTCAAGGA
GCGGCCGAGCCCCGGGCCCGCGGCAGGGCGTGCGGCGCGGGCGGCGGCGGGCGGCACGGCCTCCCCGGGGGGAGGCGCGCGGCGTGCGAG
CGCCAGCGGACCAGTGCCTGGCCGCAGCCCCCCGGCGCCAGCGCGCCAGAGCGTCATCCACGTGCAGGCGTCGGGCGCGCGGGACGAGGC
GTGCGCGCCGGCCGTGGGGGCGCTGCGGCCGTGCGCCACGTACCCGCAGCAGAACCGCTCGCTGTCGTCGCAGAGCTACAGCCCGGCGCG
CGCCGCCGCCCTGCGCACCGTCAACACGGTCGAGTCGCTGGCGCGCGCGGTGCCCGGGGCCCTACCGGGCGCGGCGGGGACGGCGGGGGC
GGCCGAGCACAAGTCGCAGACCTACACCAACGGCTTCGGCGCCCTGCGCGACGGCCTGGAGTTCGCCGACGCCGACGCGCCGACCGCGCG
CTCGAACGGTGAGTGCGGCCGTGGCGGCCCGGGGCCGGTGCAGCGGCGCTGCCAGCGCGAGAACTGTGCGTTCTACGGGCGCGCCGAGAC
CGAGCACTACTGCTCCTACTGCTACCGCGAGGAGCTGCGGCGGCGGCGCGAGGCGCGCGGGGCCCGGCCCTGAGCGGCGCGGCGCGGCGC
GGGCGGCGAGGTTCTACCTTCGAGGATTTCTTTTCCATTGTGTCGGTGTCTTTTTTACATGCCCTGGTCCACCGGAAGGCCGGCGCCTCC

>89301_89301_9_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000407381_OTUD7A_chr15_31862400_ENST00000307050_length(amino acids)=1155AA_BP=279
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEELRRLSWSGIPKPVRPMTWKLLSGYL
PANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPF
FVVFICEYIGKNWDLTAALSDYEQLRQVHTANLPHVFNEGRGPKQPEREPQPGHKVERPCLQRQDDIAQEKRLSRGISHASSAIVSLARS
HVASECNNEQFPLEMPIYTFQLPDLSVYSEDFRSFIERDLIEQATMVALEQAGRLNWWSTVCTSCKRLLPLATTGDGNCLLHAASLGMWG
FHDRDLVLRKALYTMMRTGAEREALKRRWRWQQTQQNKEEEWEREWTELLKLASSEPRTHFSKNGGTGGGVDNSEDPVYESLEEFHVFVL
AHILRRPIVVVADTMLRDSGGEAFAPIPFGGIYLPLEVPPNRCHCSPLVLAYDQAHFSALVSMEQRDQQREQAVIPLTDSEHKLLPLHFA
VDPGKDWEWGKDDNDNARLAHLILSLEAKLNLLHSYMNVTWIRIPSETRAPLAQPESPTASAGEDVQSLADSLDSDRDSVCSNSNSNNGK
NGKDKEKEKQRKEKDKTRADSVANKLGSFSKTLGIKLKKNMGGLGGLVHGKMGRANSANGKNGDSAERGKEKKAKSRKGSKEESGASAST
SPSEKTTPSPTDKAAGASPAEKGGGPRGDAWKYSTDVKLSLNILRAAMQGERKFIFAGLLLTSHRHQFHEEMIGYYLTSAQERFSAEQEQ
RRRDAATAAAAAAAAAAATAKRPPRRPETEGVPVPERASPGPPTQLVLKLKERPSPGPAAGRAARAAAGGTASPGGGARRASASGPVPGR
SPPAPARQSVIHVQASGARDEACAPAVGALRPCATYPQQNRSLSSQSYSPARAAALRTVNTVESLARAVPGALPGAAGTAGAAEHKSQTY

--------------------------------------------------------------
>89301_89301_10_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000407381_OTUD7A_chr15_31862400_ENST00000382902_length(transcript)=3772nt_BP=953nt
CTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCG
CGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCAT
CCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACC
AGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCT
GGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCC
CACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAA
GTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAGGAATTACGGAGGTTGAGCTGGTCCGGAATCCCTAAGCCAGTGCGTCCAATGAC
GTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAAACAAAAAGAATATTTTGCATTTAT
TGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGACATCCCTCGCATGAGCCCTGAAGC
GTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCACCCAGCCAGTGGATACGTTCAGGG
TATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACATAGGCAAAAACTGGGACCTGACAGCCGCTCTGAGCGACTA
TGAGCAGCTCCGCCAGGTGCACACAGCCAATCTGCCACATGTGTTCAATGAAGGGCGGGGTCCCAAGCAGCCAGAGCGAGAGCCACAGCC
CGGGCACAAGGTGGAGCGACCCTGCCTGCAGAGGCAGGACGACATTGCCCAAGAAAAGCGGCTTTCCCGGGGGATTTCCCACGCCAGCTC
AGCCATCGTCTCCCTGGCCCGGTCCCACGTGGCAAGTGAATGCAACAACGAGCAGTTCCCCCTGGAGATGCCAATCTACACATTCCAGTT
GCCAGACCTGAGCGTGTACAGCGAGGATTTCAGGAGCTTCATCGAGCGGGACTTGATCGAGCAGGCAACAATGGTGGCTTTGGAGCAGGC
AGGTCGCCTGAACTGGTGGTCCACTGTGTGCACGAGCTGTAAACGGCTTCTTCCTCTGGCCACAACAGGGGATGGGAACTGCCTTTTACA
TGCTGCTTCACTGGGAATGTGGGGGTTTCACGACCGGGACCTGGTGTTACGGAAAGCTCTCTATACCATGATGAGGACGGGAGCTGAGAG
GGAAGCCCTGAAGCGGAGGTGGAGGTGGCAGCAGACGCAGCAGAATAAGGAGTCAGGGCTGGTGTACACAGAGGAGGAGTGGGAGCGGGA
GTGGACGGAGCTGCTGAAGCTGGCCTCCAGCGAGCCGCGCACACACTTCAGCAAGAATGGCGGCACGGGCGGGGGTGTGGACAACTCTGA
GGACCCCGTGTACGAGAGCCTGGAAGAGTTCCACGTTTTTGTCCTAGCCCATATATTAAGAAGGCCCATCGTTGTTGTGGCAGATACAAT
GTTAAGAGACTCAGGTGGAGAAGCGTTCGCACCCATCCCATTCGGAGGGATCTACCTGCCCTTGGAGGTCCCTCCCAACAGATGCCACTG
CTCGCCTCTGGTTCTGGCCTATGATCAAGCCCATTTCTCTGCCCTTGTGTCCATGGAACAGAGAGACCAGCAAAGAGAACAAGCCGTGAT
CCCCCTGACGGATTCTGAGCACAAGCTGCTGCCTCTGCACTTTGCAGTGGACCCTGGCAAGGACTGGGAGTGGGGGAAAGACGACAACGA
TAACGCCCGGCTGGCCCACCTTATCCTGTCGCTAGAAGCCAAGCTGAACCTTCTGCACAGCTACATGAACGTGACGTGGATCCGGATCCC
CTCCGAGACACGGGCGCCCCTGGCACAGCCGGAGTCTCCCACGGCCTCGGCAGGGGAGGACGTGCAGTCCCTGGCCGACTCGCTGGACTC
GGACCGCGATTCGGTGTGCAGCAATTCTAACAGCAATAACGGCAAGAACGGCAAGGACAAGGAGAAGGAGAAGCAGCGCAAGGAGAAGGA
CAAGACGCGCGCCGACTCCGTGGCCAACAAGCTGGGCAGCTTCAGCAAGACGCTGGGCATCAAGCTGAAGAAAAACATGGGCGGCCTCGG
CGGCCTGGTGCACGGCAAGATGGGCCGCGCCAACTCCGCCAATGGCAAGAACGGGGACTCGGCCGAGCGGGGCAAGGAGAAGAAGGCCAA
GTCGCGCAAGGGCAGCAAGGAGGAGTCTGGTGCGTCGGCCAGCACGTCGCCGTCGGAAAAGACCACGCCGTCGCCCACAGACAAGGCAGC
GGGCGCGTCGCCGGCGGAGAAGGGCGGTGGGCCGCGGGGCGACGCCTGGAAGTACAGCACGGATGTGAAGCTGAGCCTCAACATCCTGCG
CGCCGCCATGCAGGGGGAGCGCAAGTTCATCTTCGCCGGCCTGCTGCTCACCAGCCACCGGCACCAGTTCCACGAGGAGATGATCGGCTA
CTACCTGACGAGCGCGCAGGAGCGCTTCAGCGCCGAGCAGGAGCAGCGGCGCCGCGACGCCGCTACTGCGGCCGCCGCTGCCGCCGCCGC
CGCCGCCGCCACGGCCAAGCGGCCGCCGCGCAGACCGGAGACGGAGGGCGTGCCGGTCCCGGAGCGCGCCTCTCCGGGCCCACCCACGCA
GCTGGTGCTCAAGCTCAAGGAGCGGCCGAGCCCCGGGCCCGCGGCAGGGCGTGCGGCGCGGGCGGCGGCGGGCGGCACGGCCTCCCCGGG
GGGAGGCGCGCGGCGTGCGAGCGCCAGCGGACCAGTGCCTGGCCGCAGCCCCCCGGCGCCAGCGCGCCAGAGCGTCATCCACGTGCAGGC
GTCGGGCGCGCGGGACGAGGCGTGCGCGCCGGCCGTGGGGGCGCTGCGGCCGTGCGCCACGTACCCGCAGCAGAACCGCTCGCTGTCGTC
GCAGAGCTACAGCCCGGCGCGCGCCGCCGCCCTGCGCACCGTCAACACGGTCGAGTCGCTGGCGCGCGCGGTGCCCGGGGCCCTACCGGG
CGCGGCGGGGACGGCGGGGGCGGCCGAGCACAAGTCGCAGACCTACACCAACGGCTTCGGCGCCCTGCGCGACGGCCTGGAGTTCGCCGA
CGCCGACGCGCCGACCGCGCGCTCGAACGGTGAGTGCGGCCGTGGCGGCCCGGGGCCGGTGCAGCGGCGCTGCCAGCGCGAGAACTGTGC
GTTCTACGGGCGCGCCGAGACCGAGCACTACTGCTCCTACTGCTACCGCGAGGAGCTGCGGCGGCGGCGCGAGGCGCGCGGGGCCCGGCC
CTGAGCGGCGCGGCGCGGCGCGGGCGGCGAGGTTCTACCTTCGAGGATTTCTTTTCCATTGTGTCGGTGTCTTTTTTACATGCCCTGGTC

>89301_89301_10_TBC1D22A-OTUD7A_TBC1D22A_chr22_47308084_ENST00000407381_OTUD7A_chr15_31862400_ENST00000382902_length(amino acids)=1162AA_BP=279
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAEELRRLSWSGIPKPVRPMTWKLLSGYL
PANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPF
FVVFICEYIGKNWDLTAALSDYEQLRQVHTANLPHVFNEGRGPKQPEREPQPGHKVERPCLQRQDDIAQEKRLSRGISHASSAIVSLARS
HVASECNNEQFPLEMPIYTFQLPDLSVYSEDFRSFIERDLIEQATMVALEQAGRLNWWSTVCTSCKRLLPLATTGDGNCLLHAASLGMWG
FHDRDLVLRKALYTMMRTGAEREALKRRWRWQQTQQNKESGLVYTEEEWEREWTELLKLASSEPRTHFSKNGGTGGGVDNSEDPVYESLE
EFHVFVLAHILRRPIVVVADTMLRDSGGEAFAPIPFGGIYLPLEVPPNRCHCSPLVLAYDQAHFSALVSMEQRDQQREQAVIPLTDSEHK
LLPLHFAVDPGKDWEWGKDDNDNARLAHLILSLEAKLNLLHSYMNVTWIRIPSETRAPLAQPESPTASAGEDVQSLADSLDSDRDSVCSN
SNSNNGKNGKDKEKEKQRKEKDKTRADSVANKLGSFSKTLGIKLKKNMGGLGGLVHGKMGRANSANGKNGDSAERGKEKKAKSRKGSKEE
SGASASTSPSEKTTPSPTDKAAGASPAEKGGGPRGDAWKYSTDVKLSLNILRAAMQGERKFIFAGLLLTSHRHQFHEEMIGYYLTSAQER
FSAEQEQRRRDAATAAAAAAAAAAATAKRPPRRPETEGVPVPERASPGPPTQLVLKLKERPSPGPAAGRAARAAAGGTASPGGGARRASA
SGPVPGRSPPAPARQSVIHVQASGARDEACAPAVGALRPCATYPQQNRSLSSQSYSPARAAALRTVNTVESLARAVPGALPGAAGTAGAA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TBC1D22A-OTUD7A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TBC1D22A-OTUD7A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TBC1D22A-OTUD7A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource