FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:TBL1XR1-USP13 (FusionGDB2 ID:89569)

Fusion Gene Summary for TBL1XR1-USP13

check button Fusion gene summary
Fusion gene informationFusion gene name: TBL1XR1-USP13
Fusion gene ID: 89569
HgeneTgene
Gene symbol

TBL1XR1

USP13

Gene ID

79718

8975

Gene nameTBL1X receptor 1ubiquitin specific peptidase 13
SynonymsC21|DC42|IRA1|MRD41|TBLR1ISOT3|IsoT-3
Cytomap

3q26.32

3q26.33

Type of geneprotein-codingprotein-coding
DescriptionF-box-like/WD repeat-containing protein TBL1XR1TBL1-related protein 1nuclear receptor co-repressor/HDAC3 complex subunitnuclear receptor corepressor/HDAC3 complex subunit TBLR1transducin beta like 1 X-linked receptor 1ubiquitin carboxyl-terminal hydrolase 13deubiquitinating enzyme 13ubiquitin specific peptidase 13 (isopeptidase T-3)ubiquitin specific protease 13 (isopeptidase T-3)ubiquitin thioesterase 13ubiquitin thiolesterase 13ubiquitin-specific-processing pro
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000430069, ENST00000457928, 
ENST00000482333, ENST00000496897, 
ENST00000263966, 
Fusion gene scores* DoF score51 X 31 X 15=237154 X 4 X 3=48
# samples 664
** MAII scorelog2(66/23715*10)=-5.16719003372107
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TBL1XR1 [Title/Abstract] AND USP13 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTBL1XR1(176763917)-USP13(179478900), # samples:3
Anticipated loss of major functional domain due to fusion event.TBL1XR1-USP13 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
TBL1XR1-USP13 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
TBL1XR1-USP13 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
TBL1XR1-USP13 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTBL1XR1

GO:0000122

negative regulation of transcription by RNA polymerase II

12628926

HgeneTBL1XR1

GO:0045893

positive regulation of transcription, DNA-templated

18193033

HgeneTBL1XR1

GO:0045944

positive regulation of transcription by RNA polymerase II

18193033

TgeneUSP13

GO:0010506

regulation of autophagy

21962518

TgeneUSP13

GO:0035523

protein K29-linked deubiquitination

26280536

TgeneUSP13

GO:0044313

protein K6-linked deubiquitination

26280536

TgeneUSP13

GO:0050821

protein stabilization

21659512|26280536

TgeneUSP13

GO:0070536

protein K63-linked deubiquitination

22216260|26280536


check buttonFusion gene breakpoints across TBL1XR1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across USP13 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A07G-01ATBL1XR1chr3

176763916

-USP13chr3

179478899

+
ChimerDB4BRCATCGA-A8-A07G-01ATBL1XR1chr3

176763917

-USP13chr3

179478900

+
ChimerDB4BRCATCGA-A8-A07GTBL1XR1chr3

176763916

-USP13chr3

179478899

+


Top

Fusion Gene ORF analysis for TBL1XR1-USP13

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000430069ENST00000482333TBL1XR1chr3

176763917

-USP13chr3

179478900

+
5CDS-intronENST00000430069ENST00000482333TBL1XR1chr3

176763916

-USP13chr3

179478899

+
5CDS-intronENST00000430069ENST00000496897TBL1XR1chr3

176763917

-USP13chr3

179478900

+
5CDS-intronENST00000430069ENST00000496897TBL1XR1chr3

176763916

-USP13chr3

179478899

+
5CDS-intronENST00000457928ENST00000482333TBL1XR1chr3

176763917

-USP13chr3

179478900

+
5CDS-intronENST00000457928ENST00000482333TBL1XR1chr3

176763916

-USP13chr3

179478899

+
5CDS-intronENST00000457928ENST00000496897TBL1XR1chr3

176763917

-USP13chr3

179478900

+
5CDS-intronENST00000457928ENST00000496897TBL1XR1chr3

176763916

-USP13chr3

179478899

+
Frame-shiftENST00000457928ENST00000263966TBL1XR1chr3

176763917

-USP13chr3

179478900

+
Frame-shiftENST00000457928ENST00000263966TBL1XR1chr3

176763916

-USP13chr3

179478899

+
In-frameENST00000430069ENST00000263966TBL1XR1chr3

176763917

-USP13chr3

179478900

+
In-frameENST00000430069ENST00000263966TBL1XR1chr3

176763916

-USP13chr3

179478899

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000430069TBL1XR1chr3176763917-ENST00000263966USP13chr3179478900+708911852601828522
ENST00000430069TBL1XR1chr3176763916-ENST00000263966USP13chr3179478899+708911852601828522

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000430069ENST00000263966TBL1XR1chr3176763917-USP13chr3179478900+0.00045830.99954176
ENST00000430069ENST00000263966TBL1XR1chr3176763916-USP13chr3179478899+0.00045830.99954176

Top

Fusion Genomic Features for TBL1XR1-USP13


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TBL1XR1chr3176763916-USP13chr3179478899+2.44E-070.99999976
TBL1XR1chr3176763916-USP13chr3179478899+2.44E-070.99999976
TBL1XR1chr3176763916-USP13chr3179478899+2.44E-070.99999976
TBL1XR1chr3176763916-USP13chr3179478899+2.44E-070.99999976

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for TBL1XR1-USP13


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:176763917/chr3:179478900)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000430069-1016108_118308515.0Compositional biasNote=Poly-Ala
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000457928-1016108_118308515.0Compositional biasNote=Poly-Ala
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000430069-1016108_118308515.0Compositional biasNote=Poly-Ala
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000457928-1016108_118308515.0Compositional biasNote=Poly-Ala
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000430069-101641_86308515.0DomainNote=F-box-like
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000430069-10164_36308515.0DomainLisH
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000457928-101641_86308515.0DomainNote=F-box-like
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000457928-10164_36308515.0DomainLisH
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000430069-101641_86308515.0DomainNote=F-box-like
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000430069-10164_36308515.0DomainLisH
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000457928-101641_86308515.0DomainNote=F-box-like
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000457928-10164_36308515.0DomainLisH
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000430069-1016167_206308515.0RepeatNote=WD 1
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000430069-1016223_262308515.0RepeatNote=WD 2
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000430069-1016264_303308515.0RepeatNote=WD 3
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000457928-1016167_206308515.0RepeatNote=WD 1
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000457928-1016223_262308515.0RepeatNote=WD 2
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000457928-1016264_303308515.0RepeatNote=WD 3
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000430069-1016167_206308515.0RepeatNote=WD 1
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000430069-1016223_262308515.0RepeatNote=WD 2
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000430069-1016264_303308515.0RepeatNote=WD 3
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000457928-1016167_206308515.0RepeatNote=WD 1
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000457928-1016223_262308515.0RepeatNote=WD 2
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000457928-1016264_303308515.0RepeatNote=WD 3
TgeneUSP13chr3:176763916chr3:179478899ENST000002639661521652_693649864.0DomainUBA 1
TgeneUSP13chr3:176763916chr3:179478899ENST000002639661521727_767649864.0DomainUBA 2
TgeneUSP13chr3:176763916chr3:179478899ENST000004968971521652_693584799.0DomainUBA 1
TgeneUSP13chr3:176763916chr3:179478899ENST000004968971521727_767584799.0DomainUBA 2
TgeneUSP13chr3:176763917chr3:179478900ENST000002639661521652_693649864.0DomainUBA 1
TgeneUSP13chr3:176763917chr3:179478900ENST000002639661521727_767649864.0DomainUBA 2
TgeneUSP13chr3:176763917chr3:179478900ENST000004968971521652_693584799.0DomainUBA 1
TgeneUSP13chr3:176763917chr3:179478900ENST000004968971521727_767584799.0DomainUBA 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000430069-1016306_344308515.0RepeatNote=WD 4
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000430069-1016347_386308515.0RepeatNote=WD 5
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000430069-1016389_437308515.0RepeatNote=WD 6
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000430069-1016440_479308515.0RepeatNote=WD 7
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000430069-1016481_513308515.0RepeatNote=WD 8
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000457928-1016306_344308515.0RepeatNote=WD 4
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000457928-1016347_386308515.0RepeatNote=WD 5
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000457928-1016389_437308515.0RepeatNote=WD 6
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000457928-1016440_479308515.0RepeatNote=WD 7
HgeneTBL1XR1chr3:176763916chr3:179478899ENST00000457928-1016481_513308515.0RepeatNote=WD 8
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000430069-1016306_344308515.0RepeatNote=WD 4
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000430069-1016347_386308515.0RepeatNote=WD 5
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000430069-1016389_437308515.0RepeatNote=WD 6
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000430069-1016440_479308515.0RepeatNote=WD 7
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000430069-1016481_513308515.0RepeatNote=WD 8
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000457928-1016306_344308515.0RepeatNote=WD 4
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000457928-1016347_386308515.0RepeatNote=WD 5
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000457928-1016389_437308515.0RepeatNote=WD 6
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000457928-1016440_479308515.0RepeatNote=WD 7
HgeneTBL1XR1chr3:176763917chr3:179478900ENST00000457928-1016481_513308515.0RepeatNote=WD 8
TgeneUSP13chr3:176763916chr3:179478899ENST000002639661521336_861649864.0DomainNote=USP
TgeneUSP13chr3:176763916chr3:179478899ENST000004968971521336_861584799.0DomainNote=USP
TgeneUSP13chr3:176763917chr3:179478900ENST000002639661521336_861649864.0DomainNote=USP
TgeneUSP13chr3:176763917chr3:179478900ENST000004968971521336_861584799.0DomainNote=USP
TgeneUSP13chr3:176763916chr3:179478899ENST000002639661521209_281649864.0Zinc fingerUBP-type
TgeneUSP13chr3:176763916chr3:179478899ENST000004968971521209_281584799.0Zinc fingerUBP-type
TgeneUSP13chr3:176763917chr3:179478900ENST000002639661521209_281649864.0Zinc fingerUBP-type
TgeneUSP13chr3:176763917chr3:179478900ENST000004968971521209_281584799.0Zinc fingerUBP-type


Top

Fusion Gene Sequence for TBL1XR1-USP13


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>89569_89569_1_TBL1XR1-USP13_TBL1XR1_chr3_176763916_ENST00000430069_USP13_chr3_179478899_ENST00000263966_length(transcript)=7089nt_BP=1185nt
GCGCGGCAGCCGGGCCTTGCTCCGGGACGTGTTTATTTGTAACTTAGTGCTTTTTATCGTCTTAAGGAGGTATTTGGTGGAGGCTCTTTG
AAGTTGGGTTCAGGAGTGTAGAATTGGCAAAGTTATTGCCAGCTTCCTGCATCAACAACAGCAACTTGTGATTGGCGGTGACCGGATATT
CAGTTGCACATCCCCACATCAATGCACTGCCAATGGGTTATATCCTGTGTTGTGACCTCATGGTTTAAGTGGGAATAAAGATGAGTATAA
GCAGTGATGAGGTCAACTTCTTGGTATATAGATACTTGCAAGAGTCAGGATTTTCTCATTCAGCATTTACCTTTGGTATAGAAAGCCATA
TCAGTCAGTCCAATATAAATGGTGCCCTCGTCCCACCCGCTGCATTGATTTCTATCATCCAGAAAGGTCTACAGTATGTAGAAGCAGAAG
TTAGTATTAATGAGGATGGTACCTTGTTTGATGGTCGACCAATAGAGTCTCTGTCCCTGATAGATGCCGTAATGCCTGATGTAGTACAAA
CAAGACAACAAGCTTATAGAGATAAGCTTGCACAGCAACAGGCAGCAGCTGCTGCAGCTGCCGCAGCTGCAGCCAGCCAACAAGGATCTG
CAAAAAATGGAGAAAACACAGCAAATGGGGAGGAGAATGGAGCACATACTATAGCAAATAATCATACTGATATGATGGAAGTGGATGGGG
ATGTTGAAATCCCTCCTAATAAAGCTGTTGTGTTGCGGGGCCATGAATCTGAAGTTTTTATCTGTGCCTGGAACCCTGTTAGTGATCTCC
TAGCATCAGGGTCTGGAGACTCAACAGCAAGAATATGGAATCTTAGTGAGAACAGCACCAGTGGCTCTACACAGTTAGTACTTAGACATT
GTATACGAGAAGGAGGGCAAGATGTTCCAAGCAACAAGGATGTCACATCTCTAGATTGGAATAGTGAAGGTACACTTCTAGCAACTGGTT
CCTATGATGGGTTTGCCAGAATATGGACTAAAGATGGTAACCTTGCTAGCACCTTAGGGCAGCATAAAGGCCCTATATTTGCATTAAAAT
GGAATAAGAAAGGAAATTTCATCCTAAGTGCTGGAGTAGACAAGACTACAATTATTTGGGACGCACATACTGGTGAAGCCAAGCAACAGT
TTCCTTTTCATTCAGCATCAGACATCGATGAGTCATCAGTGATGCAGCTGGCCGAGATGGGTTTCCCGCTGGAAGCATGTCGCAAGGCTG
TGTACTTCACTGGAAATATGGGCGCCGAGGTGGCCTTCAACTGGATCATTGTTCACATGGAAGAGCCAGATTTTGCTGAGCCGCTGACCA
TGCCTGGTTATGGAGGGGCAGCTTCTGCTGGAGCCTCTGTTTTTGGTGCTTCTGGACTGGATAACCAACCTCCAGAGGAAATCGTAGCTA
TCATCACCTCCATGGGATTTCAGCGAAATCAGGCTATTCAGGCACTACGAGCAACGAATAATAACCTGGAAAGAGCACTGGATTGGATCT
TTAGCCACCCTGAGTTTGAAGAAGACAGTGATTTTGTGATTGAGATGGAGAATAATGCCAATGCAAACATTATTTCTGAGGCCAAGCCCG
AAGGACCTAGAGTCAAGGATGGATCTGGAACATATGAGCTATTTGCATTCATCAGTCACATGGGAACATCCACAATGAGTGGTCATTACA
TTTGCCATATCAAAAAGGAAGGAAGATGGGTGATTTACAATGACCACAAAGTTTGTGCCTCAGAAAGGCCCCCTAAAGACCTGGGCTACA
TGTACTTTTACCGCAGGATACCAAGCTAAACCTCAAATATAAAAATTGGCGAAAAGAAGCCATACGCCTTTTTAATTTGCCAAAAAAAAA
AAGAAGAAGAAGAAGTTGAAACAACTAGACATGAAGGAATATATGGGGTATTTATCGTTTATTTAAAGAGCACGATCAGTTGACACCTTC
TGAAATAGAACTGAGAAGAAATTTCTATTAGTGATGATACACTATTATATTGTAGATAGTTTTTATAAATGTTCAAAAAGATGATGATAT
TTAAAAACAAAAAAAGTATTCATATTGCTGGTGGAGGATCTGCCATCAGCACATCAAAAATGGGGATGTGCCCCCAGCCCTCTATTTTGC
TTTGGGGGTCAGTGATAGTGGCCTCTGGAGAAACCAAATAATGTGGCCAGTGGTGTGGCCTTACCCACAACAAATGAAAAGCCCACTTGT
GTTTCATATAGAAAATCAGCAGTTGGGTGGGGCTTTATTTGTGACATAATTTTTTTCATGACATACAATAATTTCTGATGTATCCATGTA
GATATTATGCTCTGTCCATAATAGAGCCTCTGCAATGAAAGATATTTTTAATTTGTCACATTAAAATTCATAATACGATTGTGTGAATGT
GTGTGAGACTGACTGAGAGTGTGAGACTTTTACTAGAAAAGTGAGTCCACTAGAAAATCTGTGACAAGTTGGTTTTTAAAGTCTGAACAG
TTGATATTAAGCATATCTGAAAAAAGCAAGTAAATATTTTAACAAAACTATGACTCAGGAACCTTCGAGAAGATTAGTTCCCCACTTAGA
TTTTTAAGGAGTAAAAAGGGCTGAGTTATGCCTTTAAGTGCTGTCAAGAATTCACTTGGGTTTGGGACATTTGCTGGTGTAATGCTAGAT
GCCCACAGCAGCATAATATTGTACTTTGTCAAAGGTAGGTAAATTCTCTGTTTCTCAGCAGCCCTTTCCCCAAAAGGTATGGTGTTTATT
TTTAGTAAAAATAGCTAATCTCTTTTTACCATCTCACATGATAACTCTTTGGAGTCATGTCAAGTGCCCCAAATTTGTCTGTGATTTTCC
CATCTCTGAGCTCTTTATCTGCCTCCGTTTCCTTGTTTTTCTGGGGCCAGAGTCTCATCTCTGCCTTTTTTTGGTGTATCACCTTCTGAC
TTGCCTTCATTGCTTGTCTGATGTGACCAACAGTGTGATCTTGGACACACTAAGGATTTTAGATGCAAAGAAACTTTATACAACATTATG
AAAGACTATCCTTTCCATTTTGGTTATTTCAGCATTTTAGTTGCAACCTGGGATTAGATTAGAGTTTCCAACGTGATGAAAAGTGGAATG
ATAGCATTCTATAATTTCCATAATTTTCCTACTGGTCCGTACCAAATTCTAGAGTCTCTGGAGTTGCTATTTCAGAGTATTTGGTCAAAC
GAAAAAGAATTTATTGCTGTCTGTTTAACATGTATTTGTTTGGTTGAAAGGATCTTTTTAGAAACTGTAGGAAAATAAACAGAACCAACC
AGGTGAAACAAAGCACAGACATTGGGTTAGGATGTAGTGAGTTGTGAACAATCAGGATTCTGGGTGTGATGGGGGTCCCTGTCTCATAGG
TGATCCTTTGGTGCCATGTGACCGAGAGACATGGTGTCTAAGGCCCATGGCCTGGAGACCTGGGTGCTGCTCCTAGCTGACTGTGGACCT
TGGGCAAGTCCTTCATCCGTCCTGTGCCTCACTGTCCTCATCTGAACAATGGTATGATGACACCTGCCCTCTCTTTCAATCATGCTTTGA
GGATACAGTGAGATTGGTTACAGTGAACCTTCAATGAGTAGAATGTGGTATGCCATGGTGGGTTGTAGTAGATGGTGCTCCCTGCCTTTT
CTCCTCTGTTTTCCTCAATTTGGGAACAAATGAGATTGGCAGAAGGAGGGAGCTCACGGTGCAGTACTTTTCTACCAAAGTGTGCCCACT
GGTGTCACCTCCTAATGTTAACTTGGATTTCCTAAAGCAGTCCCACTCTGTTATGAGAGTCACTGACTCCCGTGGACATCCCCACAGTAA
GCAGCCTTACAAAATCCAGTCCCCTTAGGGCAGAGTGAGTGTCATAGAATAATGACTCCAAACCCACGTCAAAAATGGCTTGTTTTCAGC
GATGTTATAAAACAAAGGCCTGTTTTTTGGAATTGGGGGTGACTGGGTGGTTTGGATTGAAATGTGGACAAAGATAGCATGTGTATTTTG
AATAAAATAAAAATTTTGTAATAAAACTTTTAAAAATCAGTGATGTAAAATCAATATTTAAGACTATAGGCTATAAATTGTTTGATTTCA
TTAACTAGCCCTTTTGATGCCTAGACATGTTGTAAAAAAATTGTGCTATGGCTGCCTTTTCTTCTGCCCCACAACACAAAGGGCTATTTC
TACAAGGCAAAGTTTTGTATATGTGCTATTCTTTACTTCAGATTGAGAGTTGGGAAAAACTGGAGTAAATAATGGGTTTCTTACTTGCTT
AAAAGCATATTTATATGTGTATCTCAATATATACAAGGCAGGTTCCCCTATAAAAGTCTGGAATGTACTGCTTAATTTTACACTTGTGTA
GACACGATTATTTGTGACTGAAAAGTGGAATAACGTGTGGATTTTGTCAACTCATTATCAGTCTGTTAGCAGTCCTCTATGTGAGGCATG
GTGGTCTAATTGTGAAATTCTCCCTGTATATGGGTGTCTGTGTGAAAGACAGCACTTTCTTCCTGTAAATATCTTTTGATATCCATTTAT
GTAGAATTCCAATGAATATGTCTTTGGAAAAGGTAATGTATCAAAGTTTTTATTTTGCCAATTGATCTAAATGCCCATATAACTAATCAG
AAATCCAGTTTGGTTCAGATTGGGATTTTCTTTTAAAGAAAAAAAAAGTATGCAGAAAAGACTATTGGAAGAATCATGTGTTAGTGACAC
TTTACATCAACGTTGCTTCAATATTTTGGAATTGACCAGGCTGCTTTCTCCTACCTGCAAGAGAATGTGCCTGACATTTCCCAGTGCTTA
CTTTGGGCTATAGGAAGTCCAGCGGGGATAGCTCGAGCCTCTTGCTCCCTGAGTCATTTATTCCCTTTACCTGAACAGAGCCTTACCTGC
AATTCATAGTGAGAGCACCTGGGTCTGTATCCTGACTCCACTCTAAGTGAGGTGGGACTGAATCACTGTACCTCTCTGGGCCTTTTCATT
TGAAACAAGTGGGTTAGACTAGATTAGCTCCAAAGTCCTCTCTTGCCCTAACATTTTATTTTTATTTTCCTGTGGTTACCACTAGGGTCT
GACACGTAAAATGTGAGGGATCACTTAGAGGTTTGGATGTTATATTTTTGCATTGTTACAGCTTATACTCCCCAGTTGAGGACCTGTGTC
ATTCTTAGTGGCCCCACGACCCCTCTGTTTGTATTCCTGCTCCACTTATCTATACTTTTTTGGGTAATCATCCCACTTTTTTTTTTTCTT
GAGATGGAGTCTCGCTGTGTTGCCAAGGCTGGAGTACAGTGGTGCAATCTCAGCTCACTGCAGCCTCCTCCCGGGTTCAAGTGATTCTCC
TGCCTCAGCTTCCCAAGTAGCTGGGATTACTGGCGCACGCCACTACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTTGCCA
TGTTGGCCAGGCTGGTCTTGAACTCTTGACCTCAACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACACGCATGAGCTACCGCGTCCAGC
CCCACTTTTTTTCTACTCTTGAAAAAAACAACTTTCTAGTCCATGAGGTACTTTGGCTCCATCCCCCTCAAAAACAAAACAAAAAATCCA
TTTAAAGTGTCCTCCTAGAAAAGCCTCAGAACTGCCTTCAACTACATCTGTCACCTTTATAGAATATTTTGAAATTCTGGAAGAGGATGG
GAAACAAAATTCTAATTTAGCTAGAGCTGTGATCCCCAAATAAGTGCTGACAAAATTGTCTACCACAGAAAGGCCGTCCTTGTCATCTTG
TAGGCATCACTGCTGCTAAATCACATCAGTACATGCCTTCTGTGGGGAGATGGCAGGGGGCAGGGGCAGGACCAGGGGATGGGATTAGAT
AAAGTGTGATAATGTCCTTTAGATAAAAGAAATCCTACGCTATAGAACAAGGTTCTGTACTCTTGAGTTGGTGTCTGAGATCACCTGCAC
AGTGTTACAGAGATTTTCCACTCCATAAATCACTCTAAAAGAGTTTGCATAAGACTCGGTAGACCTGTGCTATTCAATGTGGCAGTCAAC
AGCCATATGTGGCGATGACTACTCAAAGTTTGGCTTGTTCAAATCGAGACTGTGTTGTACACATACAATACACACCAGATTTTGAAGGCT
TGGTACCAAAAAGGAATTTAAAATATTTCACCAATATTTCATATTGATAACATGCTGAAATGACACTATTTTGGATGTACTAAGTAAAAT
ATTAACAATTTAATATATTTATATAATTGAAATTAAAATTCTTTTCACCCATTTTTATTTTTTTAAAAATGTGGCCCCTAAAGAACTTCA
AATTAGACATGTGGATAACGTTATACTTCTATTGGACAGCCCCACTCTAGACTTACATGGTGTGGGGTAGGCAGTGAAATCCGTAAATAG
GAAACGCAATTCTGCAAAGTATCTAAATAGACAGAAACAACACAAATATTTTTGCTGGAGTCAGGAGCACTGTGAGGCACAGAACATCTC
CCAGAAAGCAGATTTTTTTTTTCTGCCGAAAAACCAATATATATATGTATGATCCCAATTAAAAGACAAAAGCAAATGAGCCCCAAACTG
CCTGTCTTCAGCTTTGCCTGGGAGCTGCTACCTTTGCTCTTCTAGCATCTTCTAGGTACCAAGGATATTAGCCACTTGAGGGTGTTGGGC
ATATTTGTTTCATTGTAGGCAAAATCCTCTTGTGGTTTCCCCTCCCCAGGTATTGTTGAGTCTGTTCAAAGCTGGGTGTGTTGAAACACT
GCACAAATCCTGCCACTCTTGATGTGCCGCTTGTCTCAGCCTTGGCAGAGGCTGAGTCTGTTCCTGTGCCCACCTGTCCAGCAGGTTTTG
ATGTTGGCTCCTGAAAGAGTTTGTATTTATTTTATTTTGCACTAGTCACAGTTGTTGTTAAACTGTATCAAATGTTTTGGGAGATTATTT

>89569_89569_1_TBL1XR1-USP13_TBL1XR1_chr3_176763916_ENST00000430069_USP13_chr3_179478899_ENST00000263966_length(amino acids)=522AA_BP=308
MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPD
VVQTRQQAYRDKLAQQQAAAAAAAAAAASQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV
SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIF
ALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSASDIDESSVMQLAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAE
PLTMPGYGGAASAGASVFGASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEMENNANANIISE

--------------------------------------------------------------
>89569_89569_2_TBL1XR1-USP13_TBL1XR1_chr3_176763917_ENST00000430069_USP13_chr3_179478900_ENST00000263966_length(transcript)=7089nt_BP=1185nt
GCGCGGCAGCCGGGCCTTGCTCCGGGACGTGTTTATTTGTAACTTAGTGCTTTTTATCGTCTTAAGGAGGTATTTGGTGGAGGCTCTTTG
AAGTTGGGTTCAGGAGTGTAGAATTGGCAAAGTTATTGCCAGCTTCCTGCATCAACAACAGCAACTTGTGATTGGCGGTGACCGGATATT
CAGTTGCACATCCCCACATCAATGCACTGCCAATGGGTTATATCCTGTGTTGTGACCTCATGGTTTAAGTGGGAATAAAGATGAGTATAA
GCAGTGATGAGGTCAACTTCTTGGTATATAGATACTTGCAAGAGTCAGGATTTTCTCATTCAGCATTTACCTTTGGTATAGAAAGCCATA
TCAGTCAGTCCAATATAAATGGTGCCCTCGTCCCACCCGCTGCATTGATTTCTATCATCCAGAAAGGTCTACAGTATGTAGAAGCAGAAG
TTAGTATTAATGAGGATGGTACCTTGTTTGATGGTCGACCAATAGAGTCTCTGTCCCTGATAGATGCCGTAATGCCTGATGTAGTACAAA
CAAGACAACAAGCTTATAGAGATAAGCTTGCACAGCAACAGGCAGCAGCTGCTGCAGCTGCCGCAGCTGCAGCCAGCCAACAAGGATCTG
CAAAAAATGGAGAAAACACAGCAAATGGGGAGGAGAATGGAGCACATACTATAGCAAATAATCATACTGATATGATGGAAGTGGATGGGG
ATGTTGAAATCCCTCCTAATAAAGCTGTTGTGTTGCGGGGCCATGAATCTGAAGTTTTTATCTGTGCCTGGAACCCTGTTAGTGATCTCC
TAGCATCAGGGTCTGGAGACTCAACAGCAAGAATATGGAATCTTAGTGAGAACAGCACCAGTGGCTCTACACAGTTAGTACTTAGACATT
GTATACGAGAAGGAGGGCAAGATGTTCCAAGCAACAAGGATGTCACATCTCTAGATTGGAATAGTGAAGGTACACTTCTAGCAACTGGTT
CCTATGATGGGTTTGCCAGAATATGGACTAAAGATGGTAACCTTGCTAGCACCTTAGGGCAGCATAAAGGCCCTATATTTGCATTAAAAT
GGAATAAGAAAGGAAATTTCATCCTAAGTGCTGGAGTAGACAAGACTACAATTATTTGGGACGCACATACTGGTGAAGCCAAGCAACAGT
TTCCTTTTCATTCAGCATCAGACATCGATGAGTCATCAGTGATGCAGCTGGCCGAGATGGGTTTCCCGCTGGAAGCATGTCGCAAGGCTG
TGTACTTCACTGGAAATATGGGCGCCGAGGTGGCCTTCAACTGGATCATTGTTCACATGGAAGAGCCAGATTTTGCTGAGCCGCTGACCA
TGCCTGGTTATGGAGGGGCAGCTTCTGCTGGAGCCTCTGTTTTTGGTGCTTCTGGACTGGATAACCAACCTCCAGAGGAAATCGTAGCTA
TCATCACCTCCATGGGATTTCAGCGAAATCAGGCTATTCAGGCACTACGAGCAACGAATAATAACCTGGAAAGAGCACTGGATTGGATCT
TTAGCCACCCTGAGTTTGAAGAAGACAGTGATTTTGTGATTGAGATGGAGAATAATGCCAATGCAAACATTATTTCTGAGGCCAAGCCCG
AAGGACCTAGAGTCAAGGATGGATCTGGAACATATGAGCTATTTGCATTCATCAGTCACATGGGAACATCCACAATGAGTGGTCATTACA
TTTGCCATATCAAAAAGGAAGGAAGATGGGTGATTTACAATGACCACAAAGTTTGTGCCTCAGAAAGGCCCCCTAAAGACCTGGGCTACA
TGTACTTTTACCGCAGGATACCAAGCTAAACCTCAAATATAAAAATTGGCGAAAAGAAGCCATACGCCTTTTTAATTTGCCAAAAAAAAA
AAGAAGAAGAAGAAGTTGAAACAACTAGACATGAAGGAATATATGGGGTATTTATCGTTTATTTAAAGAGCACGATCAGTTGACACCTTC
TGAAATAGAACTGAGAAGAAATTTCTATTAGTGATGATACACTATTATATTGTAGATAGTTTTTATAAATGTTCAAAAAGATGATGATAT
TTAAAAACAAAAAAAGTATTCATATTGCTGGTGGAGGATCTGCCATCAGCACATCAAAAATGGGGATGTGCCCCCAGCCCTCTATTTTGC
TTTGGGGGTCAGTGATAGTGGCCTCTGGAGAAACCAAATAATGTGGCCAGTGGTGTGGCCTTACCCACAACAAATGAAAAGCCCACTTGT
GTTTCATATAGAAAATCAGCAGTTGGGTGGGGCTTTATTTGTGACATAATTTTTTTCATGACATACAATAATTTCTGATGTATCCATGTA
GATATTATGCTCTGTCCATAATAGAGCCTCTGCAATGAAAGATATTTTTAATTTGTCACATTAAAATTCATAATACGATTGTGTGAATGT
GTGTGAGACTGACTGAGAGTGTGAGACTTTTACTAGAAAAGTGAGTCCACTAGAAAATCTGTGACAAGTTGGTTTTTAAAGTCTGAACAG
TTGATATTAAGCATATCTGAAAAAAGCAAGTAAATATTTTAACAAAACTATGACTCAGGAACCTTCGAGAAGATTAGTTCCCCACTTAGA
TTTTTAAGGAGTAAAAAGGGCTGAGTTATGCCTTTAAGTGCTGTCAAGAATTCACTTGGGTTTGGGACATTTGCTGGTGTAATGCTAGAT
GCCCACAGCAGCATAATATTGTACTTTGTCAAAGGTAGGTAAATTCTCTGTTTCTCAGCAGCCCTTTCCCCAAAAGGTATGGTGTTTATT
TTTAGTAAAAATAGCTAATCTCTTTTTACCATCTCACATGATAACTCTTTGGAGTCATGTCAAGTGCCCCAAATTTGTCTGTGATTTTCC
CATCTCTGAGCTCTTTATCTGCCTCCGTTTCCTTGTTTTTCTGGGGCCAGAGTCTCATCTCTGCCTTTTTTTGGTGTATCACCTTCTGAC
TTGCCTTCATTGCTTGTCTGATGTGACCAACAGTGTGATCTTGGACACACTAAGGATTTTAGATGCAAAGAAACTTTATACAACATTATG
AAAGACTATCCTTTCCATTTTGGTTATTTCAGCATTTTAGTTGCAACCTGGGATTAGATTAGAGTTTCCAACGTGATGAAAAGTGGAATG
ATAGCATTCTATAATTTCCATAATTTTCCTACTGGTCCGTACCAAATTCTAGAGTCTCTGGAGTTGCTATTTCAGAGTATTTGGTCAAAC
GAAAAAGAATTTATTGCTGTCTGTTTAACATGTATTTGTTTGGTTGAAAGGATCTTTTTAGAAACTGTAGGAAAATAAACAGAACCAACC
AGGTGAAACAAAGCACAGACATTGGGTTAGGATGTAGTGAGTTGTGAACAATCAGGATTCTGGGTGTGATGGGGGTCCCTGTCTCATAGG
TGATCCTTTGGTGCCATGTGACCGAGAGACATGGTGTCTAAGGCCCATGGCCTGGAGACCTGGGTGCTGCTCCTAGCTGACTGTGGACCT
TGGGCAAGTCCTTCATCCGTCCTGTGCCTCACTGTCCTCATCTGAACAATGGTATGATGACACCTGCCCTCTCTTTCAATCATGCTTTGA
GGATACAGTGAGATTGGTTACAGTGAACCTTCAATGAGTAGAATGTGGTATGCCATGGTGGGTTGTAGTAGATGGTGCTCCCTGCCTTTT
CTCCTCTGTTTTCCTCAATTTGGGAACAAATGAGATTGGCAGAAGGAGGGAGCTCACGGTGCAGTACTTTTCTACCAAAGTGTGCCCACT
GGTGTCACCTCCTAATGTTAACTTGGATTTCCTAAAGCAGTCCCACTCTGTTATGAGAGTCACTGACTCCCGTGGACATCCCCACAGTAA
GCAGCCTTACAAAATCCAGTCCCCTTAGGGCAGAGTGAGTGTCATAGAATAATGACTCCAAACCCACGTCAAAAATGGCTTGTTTTCAGC
GATGTTATAAAACAAAGGCCTGTTTTTTGGAATTGGGGGTGACTGGGTGGTTTGGATTGAAATGTGGACAAAGATAGCATGTGTATTTTG
AATAAAATAAAAATTTTGTAATAAAACTTTTAAAAATCAGTGATGTAAAATCAATATTTAAGACTATAGGCTATAAATTGTTTGATTTCA
TTAACTAGCCCTTTTGATGCCTAGACATGTTGTAAAAAAATTGTGCTATGGCTGCCTTTTCTTCTGCCCCACAACACAAAGGGCTATTTC
TACAAGGCAAAGTTTTGTATATGTGCTATTCTTTACTTCAGATTGAGAGTTGGGAAAAACTGGAGTAAATAATGGGTTTCTTACTTGCTT
AAAAGCATATTTATATGTGTATCTCAATATATACAAGGCAGGTTCCCCTATAAAAGTCTGGAATGTACTGCTTAATTTTACACTTGTGTA
GACACGATTATTTGTGACTGAAAAGTGGAATAACGTGTGGATTTTGTCAACTCATTATCAGTCTGTTAGCAGTCCTCTATGTGAGGCATG
GTGGTCTAATTGTGAAATTCTCCCTGTATATGGGTGTCTGTGTGAAAGACAGCACTTTCTTCCTGTAAATATCTTTTGATATCCATTTAT
GTAGAATTCCAATGAATATGTCTTTGGAAAAGGTAATGTATCAAAGTTTTTATTTTGCCAATTGATCTAAATGCCCATATAACTAATCAG
AAATCCAGTTTGGTTCAGATTGGGATTTTCTTTTAAAGAAAAAAAAAGTATGCAGAAAAGACTATTGGAAGAATCATGTGTTAGTGACAC
TTTACATCAACGTTGCTTCAATATTTTGGAATTGACCAGGCTGCTTTCTCCTACCTGCAAGAGAATGTGCCTGACATTTCCCAGTGCTTA
CTTTGGGCTATAGGAAGTCCAGCGGGGATAGCTCGAGCCTCTTGCTCCCTGAGTCATTTATTCCCTTTACCTGAACAGAGCCTTACCTGC
AATTCATAGTGAGAGCACCTGGGTCTGTATCCTGACTCCACTCTAAGTGAGGTGGGACTGAATCACTGTACCTCTCTGGGCCTTTTCATT
TGAAACAAGTGGGTTAGACTAGATTAGCTCCAAAGTCCTCTCTTGCCCTAACATTTTATTTTTATTTTCCTGTGGTTACCACTAGGGTCT
GACACGTAAAATGTGAGGGATCACTTAGAGGTTTGGATGTTATATTTTTGCATTGTTACAGCTTATACTCCCCAGTTGAGGACCTGTGTC
ATTCTTAGTGGCCCCACGACCCCTCTGTTTGTATTCCTGCTCCACTTATCTATACTTTTTTGGGTAATCATCCCACTTTTTTTTTTTCTT
GAGATGGAGTCTCGCTGTGTTGCCAAGGCTGGAGTACAGTGGTGCAATCTCAGCTCACTGCAGCCTCCTCCCGGGTTCAAGTGATTCTCC
TGCCTCAGCTTCCCAAGTAGCTGGGATTACTGGCGCACGCCACTACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTTGCCA
TGTTGGCCAGGCTGGTCTTGAACTCTTGACCTCAACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACACGCATGAGCTACCGCGTCCAGC
CCCACTTTTTTTCTACTCTTGAAAAAAACAACTTTCTAGTCCATGAGGTACTTTGGCTCCATCCCCCTCAAAAACAAAACAAAAAATCCA
TTTAAAGTGTCCTCCTAGAAAAGCCTCAGAACTGCCTTCAACTACATCTGTCACCTTTATAGAATATTTTGAAATTCTGGAAGAGGATGG
GAAACAAAATTCTAATTTAGCTAGAGCTGTGATCCCCAAATAAGTGCTGACAAAATTGTCTACCACAGAAAGGCCGTCCTTGTCATCTTG
TAGGCATCACTGCTGCTAAATCACATCAGTACATGCCTTCTGTGGGGAGATGGCAGGGGGCAGGGGCAGGACCAGGGGATGGGATTAGAT
AAAGTGTGATAATGTCCTTTAGATAAAAGAAATCCTACGCTATAGAACAAGGTTCTGTACTCTTGAGTTGGTGTCTGAGATCACCTGCAC
AGTGTTACAGAGATTTTCCACTCCATAAATCACTCTAAAAGAGTTTGCATAAGACTCGGTAGACCTGTGCTATTCAATGTGGCAGTCAAC
AGCCATATGTGGCGATGACTACTCAAAGTTTGGCTTGTTCAAATCGAGACTGTGTTGTACACATACAATACACACCAGATTTTGAAGGCT
TGGTACCAAAAAGGAATTTAAAATATTTCACCAATATTTCATATTGATAACATGCTGAAATGACACTATTTTGGATGTACTAAGTAAAAT
ATTAACAATTTAATATATTTATATAATTGAAATTAAAATTCTTTTCACCCATTTTTATTTTTTTAAAAATGTGGCCCCTAAAGAACTTCA
AATTAGACATGTGGATAACGTTATACTTCTATTGGACAGCCCCACTCTAGACTTACATGGTGTGGGGTAGGCAGTGAAATCCGTAAATAG
GAAACGCAATTCTGCAAAGTATCTAAATAGACAGAAACAACACAAATATTTTTGCTGGAGTCAGGAGCACTGTGAGGCACAGAACATCTC
CCAGAAAGCAGATTTTTTTTTTCTGCCGAAAAACCAATATATATATGTATGATCCCAATTAAAAGACAAAAGCAAATGAGCCCCAAACTG
CCTGTCTTCAGCTTTGCCTGGGAGCTGCTACCTTTGCTCTTCTAGCATCTTCTAGGTACCAAGGATATTAGCCACTTGAGGGTGTTGGGC
ATATTTGTTTCATTGTAGGCAAAATCCTCTTGTGGTTTCCCCTCCCCAGGTATTGTTGAGTCTGTTCAAAGCTGGGTGTGTTGAAACACT
GCACAAATCCTGCCACTCTTGATGTGCCGCTTGTCTCAGCCTTGGCAGAGGCTGAGTCTGTTCCTGTGCCCACCTGTCCAGCAGGTTTTG
ATGTTGGCTCCTGAAAGAGTTTGTATTTATTTTATTTTGCACTAGTCACAGTTGTTGTTAAACTGTATCAAATGTTTTGGGAGATTATTT

>89569_89569_2_TBL1XR1-USP13_TBL1XR1_chr3_176763917_ENST00000430069_USP13_chr3_179478900_ENST00000263966_length(amino acids)=522AA_BP=308
MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPD
VVQTRQQAYRDKLAQQQAAAAAAAAAAASQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV
SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIF
ALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSASDIDESSVMQLAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAE
PLTMPGYGGAASAGASVFGASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEMENNANANIISE

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for TBL1XR1-USP13


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for TBL1XR1-USP13


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for TBL1XR1-USP13


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource