FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:TCF12-BPGM (FusionGDB2 ID:89697)

Fusion Gene Summary for TCF12-BPGM

check button Fusion gene summary
Fusion gene informationFusion gene name: TCF12-BPGM
Fusion gene ID: 89697
HgeneTgene
Gene symbol

TCF12

BPGM

Gene ID

6938

669

Gene nametranscription factor 12bisphosphoglycerate mutase
SynonymsCRS3|HEB|HTF4|HsT17266|TCF-12|bHLHb20|p64DPGM|ECYT8
Cytomap

15q21.3

7q33

Type of geneprotein-codingprotein-coding
Descriptiontranscription factor 12DNA-binding protein HTF4E-box-binding proteinclass B basic helix-loop-helix protein 20helix-loop-helix transcription factor 4transcription factor HTF-4bisphosphoglycerate mutase2,3-bisphosphoglycerate mutase, erythrocyte2,3-bisphosphoglycerate synthase2,3-diphosphoglycerate mutaseBPG-dependent PGAMerythrocyte 2,3-bisphosphoglycerate mutasetestis secretory sperm-binding protein Li 202a
Modification date2020031320200313
UniProtAcc.

P07738

Ensembl transtripts involved in fusion geneENST00000267811, ENST00000333725, 
ENST00000438423, ENST00000452095, 
ENST00000557843, ENST00000343827, 
ENST00000537840, ENST00000543579, 
ENST00000559703, ENST00000559710, 
ENST00000560764, 		ENST00000418040, 
ENST00000344924, ENST00000393132, 
Fusion gene scores* DoF score29 X 19 X 12=66123 X 3 X 2=18
# samples 323
** MAII scorelog2(32/6612*10)=-4.36894291440495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: TCF12 [Title/Abstract] AND BPGM [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTCF12(57213296)-BPGM(134363604), # samples:1
Anticipated loss of major functional domain due to fusion event.TCF12-BPGM seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
TCF12-BPGM seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
TCF12-BPGM seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTCF12

GO:0045944

positive regulation of transcription by RNA polymerase II

11802795


check buttonFusion gene breakpoints across TCF12 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BPGM (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E2-A1IJTCF12chr15

57213296

+BPGMchr7

134363604

+


Top

Fusion Gene ORF analysis for TCF12-BPGM

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000267811ENST00000418040TCF12chr15

57213296

+BPGMchr7

134363604

+
Frame-shiftENST00000333725ENST00000418040TCF12chr15

57213296

+BPGMchr7

134363604

+
Frame-shiftENST00000438423ENST00000418040TCF12chr15

57213296

+BPGMchr7

134363604

+
Frame-shiftENST00000452095ENST00000418040TCF12chr15

57213296

+BPGMchr7

134363604

+
Frame-shiftENST00000557843ENST00000418040TCF12chr15

57213296

+BPGMchr7

134363604

+
In-frameENST00000267811ENST00000344924TCF12chr15

57213296

+BPGMchr7

134363604

+
In-frameENST00000267811ENST00000393132TCF12chr15

57213296

+BPGMchr7

134363604

+
In-frameENST00000333725ENST00000344924TCF12chr15

57213296

+BPGMchr7

134363604

+
In-frameENST00000333725ENST00000393132TCF12chr15

57213296

+BPGMchr7

134363604

+
In-frameENST00000438423ENST00000344924TCF12chr15

57213296

+BPGMchr7

134363604

+
In-frameENST00000438423ENST00000393132TCF12chr15

57213296

+BPGMchr7

134363604

+
In-frameENST00000452095ENST00000344924TCF12chr15

57213296

+BPGMchr7

134363604

+
In-frameENST00000452095ENST00000393132TCF12chr15

57213296

+BPGMchr7

134363604

+
In-frameENST00000557843ENST00000344924TCF12chr15

57213296

+BPGMchr7

134363604

+
In-frameENST00000557843ENST00000393132TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000343827ENST00000344924TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000343827ENST00000393132TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000343827ENST00000418040TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000537840ENST00000344924TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000537840ENST00000393132TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000537840ENST00000418040TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000543579ENST00000344924TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000543579ENST00000393132TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000543579ENST00000418040TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000559703ENST00000344924TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000559703ENST00000393132TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000559703ENST00000418040TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000559710ENST00000344924TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000559710ENST00000393132TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000559710ENST00000418040TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000560764ENST00000344924TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000560764ENST00000393132TCF12chr15

57213296

+BPGMchr7

134363604

+
intron-3CDSENST00000560764ENST00000418040TCF12chr15

57213296

+BPGMchr7

134363604

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000438423TCF12chr1557213296+ENST00000344924BPGMchr7134363604+1405444260622120
ENST00000438423TCF12chr1557213296+ENST00000393132BPGMchr7134363604+1405444260622120
ENST00000267811TCF12chr1557213296+ENST00000344924BPGMchr7134363604+1413452304630108
ENST00000267811TCF12chr1557213296+ENST00000393132BPGMchr7134363604+1413452304630108
ENST00000452095TCF12chr1557213296+ENST00000344924BPGMchr7134363604+1403442294620108
ENST00000452095TCF12chr1557213296+ENST00000393132BPGMchr7134363604+1403442294620108
ENST00000333725TCF12chr1557213296+ENST00000344924BPGMchr7134363604+1344383235561108
ENST00000333725TCF12chr1557213296+ENST00000393132BPGMchr7134363604+1344383235561108
ENST00000557843TCF12chr1557213296+ENST00000344924BPGMchr7134363604+119623551413120
ENST00000557843TCF12chr1557213296+ENST00000393132BPGMchr7134363604+119623551413120

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000438423ENST00000344924TCF12chr1557213296+BPGMchr7134363604+0.0253199530.97468
ENST00000438423ENST00000393132TCF12chr1557213296+BPGMchr7134363604+0.0253199530.97468
ENST00000267811ENST00000344924TCF12chr1557213296+BPGMchr7134363604+0.0275275650.9724725
ENST00000267811ENST00000393132TCF12chr1557213296+BPGMchr7134363604+0.0275275650.9724725
ENST00000452095ENST00000344924TCF12chr1557213296+BPGMchr7134363604+0.036137420.9638626
ENST00000452095ENST00000393132TCF12chr1557213296+BPGMchr7134363604+0.036137420.9638626
ENST00000333725ENST00000344924TCF12chr1557213296+BPGMchr7134363604+0.0193751790.98062485
ENST00000333725ENST00000393132TCF12chr1557213296+BPGMchr7134363604+0.0193751790.98062485
ENST00000557843ENST00000344924TCF12chr1557213296+BPGMchr7134363604+0.024635980.9753641
ENST00000557843ENST00000393132TCF12chr1557213296+BPGMchr7134363604+0.024635980.9753641

Top

Fusion Genomic Features for TCF12-BPGM


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TCF12chr1557213296+BPGMchr7134363604+2.60E-050.999974
TCF12chr1557213296+BPGMchr7134363604+2.60E-050.999974

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for TCF12-BPGM


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:57213296/chr7:134363604)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.BPGM

P07738

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. {ECO:0000269|PubMed:21045285}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTCF12chr15:57213296chr7:134363604ENST00000267811+32019_27491821.3333333333333MotifNote=9aaTAD
HgeneTCF12chr15:57213296chr7:134363604ENST00000333725+32119_27491420.0MotifNote=9aaTAD
HgeneTCF12chr15:57213296chr7:134363604ENST00000438423+32119_27491398.3333333333333MotifNote=9aaTAD
HgeneTCF12chr15:57213296chr7:134363604ENST00000557843+32019_27491301.0MotifNote=9aaTAD

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTCF12chr15:57213296chr7:134363604ENST00000267811+320577_630491821.3333333333333DomainbHLH
HgeneTCF12chr15:57213296chr7:134363604ENST00000333725+321577_630491420.0DomainbHLH
HgeneTCF12chr15:57213296chr7:134363604ENST00000343827+113577_63001254.6666666666667DomainbHLH
HgeneTCF12chr15:57213296chr7:134363604ENST00000438423+321577_630491398.3333333333333DomainbHLH
HgeneTCF12chr15:57213296chr7:134363604ENST00000557843+320577_630491301.0DomainbHLH
HgeneTCF12chr15:57213296chr7:134363604ENST00000343827+11319_2701254.6666666666667MotifNote=9aaTAD
HgeneTCF12chr15:57213296chr7:134363604ENST00000267811+320119_140491821.3333333333333RegionNote=Leucine-zipper
HgeneTCF12chr15:57213296chr7:134363604ENST00000267811+320632_655491821.3333333333333RegionNote=Class A specific domain
HgeneTCF12chr15:57213296chr7:134363604ENST00000333725+321119_140491420.0RegionNote=Leucine-zipper
HgeneTCF12chr15:57213296chr7:134363604ENST00000333725+321632_655491420.0RegionNote=Class A specific domain
HgeneTCF12chr15:57213296chr7:134363604ENST00000343827+113119_14001254.6666666666667RegionNote=Leucine-zipper
HgeneTCF12chr15:57213296chr7:134363604ENST00000343827+113632_65501254.6666666666667RegionNote=Class A specific domain
HgeneTCF12chr15:57213296chr7:134363604ENST00000438423+321119_140491398.3333333333333RegionNote=Leucine-zipper
HgeneTCF12chr15:57213296chr7:134363604ENST00000438423+321632_655491398.3333333333333RegionNote=Class A specific domain
HgeneTCF12chr15:57213296chr7:134363604ENST00000557843+320119_140491301.0RegionNote=Leucine-zipper
HgeneTCF12chr15:57213296chr7:134363604ENST00000557843+320632_655491301.0RegionNote=Class A specific domain
TgeneBPGMchr15:57213296chr7:134363604ENST000003449241310_17200260.0RegionSubstrate binding
TgeneBPGMchr15:57213296chr7:134363604ENST0000034492413116_117200260.0RegionSubstrate binding
TgeneBPGMchr15:57213296chr7:134363604ENST0000034492413189_190200260.0RegionSubstrate binding
TgeneBPGMchr15:57213296chr7:134363604ENST000003449241323_24200260.0RegionSubstrate binding
TgeneBPGMchr15:57213296chr7:134363604ENST000003449241389_92200260.0RegionSubstrate binding
TgeneBPGMchr15:57213296chr7:134363604ENST000003931322410_17200260.0RegionSubstrate binding
TgeneBPGMchr15:57213296chr7:134363604ENST0000039313224116_117200260.0RegionSubstrate binding
TgeneBPGMchr15:57213296chr7:134363604ENST0000039313224189_190200260.0RegionSubstrate binding
TgeneBPGMchr15:57213296chr7:134363604ENST000003931322423_24200260.0RegionSubstrate binding
TgeneBPGMchr15:57213296chr7:134363604ENST000003931322489_92200260.0RegionSubstrate binding
TgeneBPGMchr15:57213296chr7:134363604ENST000004180402410_17200260.0RegionSubstrate binding
TgeneBPGMchr15:57213296chr7:134363604ENST0000041804024116_117200260.0RegionSubstrate binding
TgeneBPGMchr15:57213296chr7:134363604ENST0000041804024189_190200260.0RegionSubstrate binding
TgeneBPGMchr15:57213296chr7:134363604ENST000004180402423_24200260.0RegionSubstrate binding
TgeneBPGMchr15:57213296chr7:134363604ENST000004180402489_92200260.0RegionSubstrate binding


Top

Fusion Gene Sequence for TCF12-BPGM


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>89697_89697_1_TCF12-BPGM_TCF12_chr15_57213296_ENST00000267811_BPGM_chr7_134363604_ENST00000344924_length(transcript)=1413nt_BP=452nt
CGCGGAGGGATCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTATTC
GGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGCAA
AGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAG
ACGGGGCGGCAGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGA
CCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATC
AGGTATCTCAGATGAAGACATCATCAACATTACTCTTCCTACTGGAGTCCCCATTCTTCTGGAATTGGATGAAAACCTGCGTGCTGTTGG
GCCTCATCAGTTCCTGGGTGACCAAGAGGCGATCCAAGCAGCCATTAAGAAAGTAGAAGATCAAGGAAAAGTGAAACAAGCTAAAAAATA
GTCTTTCTCAACTGTTGGCTAAGAAGAAATGCAAAAGAAGTGGCATAGGAGTGTGTTATGGGTGCTGAACTCTCTCTCTTTTTCCCCGAT
TTTCCAGAGCTAGGCTGTGGAGTAGAGTTTGTATAGGTAACTAGGTAACTTATTGTGGCCCAGATAAGGCTTTAGGATGCCTCAGTGCTT
ATGTCATAGCCTTATGAGTTAGCTTTCTTGCTAGCCCCCTAGTCGGTCACCAAACTAGTAACTAGTGGGGCTTAATGAAGGTCATAAGTT
TCTGAGATGGGAGAGCAACAAGTAGAGATGAAGTTAAAGGTATTTATCATTCAAGAAATCATTATTGAGTCACCATTGACAGGCACTATT
CTAATCAGTAGTTCACTTTAATATTTAATAAGATTTTCTGGGATAACAGTAAGGGATATTAGATAATATACCGTATGTATTTATTACTAG
TCTTTTCCTCTAGGAAAAGGGATACTTTGATAATTAAGGCCAGAGGCCCATTAGTTGAGAAAGTCACAGATATATTTCTCCAAGAAAGCC
AACAACCACCACCACAATGACAGAAATGACAACAAGGCCCTTTAACTTGTCTTCTAGTTTAGAGACATCCTTCATTTGACATTTAGTAGA
ATTCCTCTTTGGCCACAAGAATAAGCAGCAAATAAACAACTATGGCTGTTGAGGTTCTCATTTTGGTTTGTTTTAATTTTTTGAACTTTG

>89697_89697_1_TCF12-BPGM_TCF12_chr15_57213296_ENST00000267811_BPGM_chr7_134363604_ENST00000344924_length(amino acids)=108AA_BP=49
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAI

--------------------------------------------------------------
>89697_89697_2_TCF12-BPGM_TCF12_chr15_57213296_ENST00000267811_BPGM_chr7_134363604_ENST00000393132_length(transcript)=1413nt_BP=452nt
CGCGGAGGGATCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTATTC
GGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGCAA
AGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAG
ACGGGGCGGCAGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGA
CCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATC
AGGTATCTCAGATGAAGACATCATCAACATTACTCTTCCTACTGGAGTCCCCATTCTTCTGGAATTGGATGAAAACCTGCGTGCTGTTGG
GCCTCATCAGTTCCTGGGTGACCAAGAGGCGATCCAAGCAGCCATTAAGAAAGTAGAAGATCAAGGAAAAGTGAAACAAGCTAAAAAATA
GTCTTTCTCAACTGTTGGCTAAGAAGAAATGCAAAAGAAGTGGCATAGGAGTGTGTTATGGGTGCTGAACTCTCTCTCTTTTTCCCCGAT
TTTCCAGAGCTAGGCTGTGGAGTAGAGTTTGTATAGGTAACTAGGTAACTTATTGTGGCCCAGATAAGGCTTTAGGATGCCTCAGTGCTT
ATGTCATAGCCTTATGAGTTAGCTTTCTTGCTAGCCCCCTAGTCGGTCACCAAACTAGTAACTAGTGGGGCTTAATGAAGGTCATAAGTT
TCTGAGATGGGAGAGCAACAAGTAGAGATGAAGTTAAAGGTATTTATCATTCAAGAAATCATTATTGAGTCACCATTGACAGGCACTATT
CTAATCAGTAGTTCACTTTAATATTTAATAAGATTTTCTGGGATAACAGTAAGGGATATTAGATAATATACCGTATGTATTTATTACTAG
TCTTTTCCTCTAGGAAAAGGGATACTTTGATAATTAAGGCCAGAGGCCCATTAGTTGAGAAAGTCACAGATATATTTCTCCAAGAAAGCC
AACAACCACCACCACAATGACAGAAATGACAACAAGGCCCTTTAACTTGTCTTCTAGTTTAGAGACATCCTTCATTTGACATTTAGTAGA
ATTCCTCTTTGGCCACAAGAATAAGCAGCAAATAAACAACTATGGCTGTTGAGGTTCTCATTTTGGTTTGTTTTAATTTTTTGAACTTTG

>89697_89697_2_TCF12-BPGM_TCF12_chr15_57213296_ENST00000267811_BPGM_chr7_134363604_ENST00000393132_length(amino acids)=108AA_BP=49
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAI

--------------------------------------------------------------
>89697_89697_3_TCF12-BPGM_TCF12_chr15_57213296_ENST00000333725_BPGM_chr7_134363604_ENST00000344924_length(transcript)=1344nt_BP=383nt
AGAGACCCACAAGTTCTATTCGGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGAC
CCGAGAGCTCGTGCGGGGCAAAGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAA
TCGGGGTGGTTGGATGCGGAGACGGGGCGGCAGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGG
GACCGACAAGGAGCTGAGCGACCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGG
AAGCAGTCAATTCAGTGGATCAGGTATCTCAGATGAAGACATCATCAACATTACTCTTCCTACTGGAGTCCCCATTCTTCTGGAATTGGA
TGAAAACCTGCGTGCTGTTGGGCCTCATCAGTTCCTGGGTGACCAAGAGGCGATCCAAGCAGCCATTAAGAAAGTAGAAGATCAAGGAAA
AGTGAAACAAGCTAAAAAATAGTCTTTCTCAACTGTTGGCTAAGAAGAAATGCAAAAGAAGTGGCATAGGAGTGTGTTATGGGTGCTGAA
CTCTCTCTCTTTTTCCCCGATTTTCCAGAGCTAGGCTGTGGAGTAGAGTTTGTATAGGTAACTAGGTAACTTATTGTGGCCCAGATAAGG
CTTTAGGATGCCTCAGTGCTTATGTCATAGCCTTATGAGTTAGCTTTCTTGCTAGCCCCCTAGTCGGTCACCAAACTAGTAACTAGTGGG
GCTTAATGAAGGTCATAAGTTTCTGAGATGGGAGAGCAACAAGTAGAGATGAAGTTAAAGGTATTTATCATTCAAGAAATCATTATTGAG
TCACCATTGACAGGCACTATTCTAATCAGTAGTTCACTTTAATATTTAATAAGATTTTCTGGGATAACAGTAAGGGATATTAGATAATAT
ACCGTATGTATTTATTACTAGTCTTTTCCTCTAGGAAAAGGGATACTTTGATAATTAAGGCCAGAGGCCCATTAGTTGAGAAAGTCACAG
ATATATTTCTCCAAGAAAGCCAACAACCACCACCACAATGACAGAAATGACAACAAGGCCCTTTAACTTGTCTTCTAGTTTAGAGACATC
CTTCATTTGACATTTAGTAGAATTCCTCTTTGGCCACAAGAATAAGCAGCAAATAAACAACTATGGCTGTTGAGGTTCTCATTTTGGTTT

>89697_89697_3_TCF12-BPGM_TCF12_chr15_57213296_ENST00000333725_BPGM_chr7_134363604_ENST00000344924_length(amino acids)=108AA_BP=49
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAI

--------------------------------------------------------------
>89697_89697_4_TCF12-BPGM_TCF12_chr15_57213296_ENST00000333725_BPGM_chr7_134363604_ENST00000393132_length(transcript)=1344nt_BP=383nt
AGAGACCCACAAGTTCTATTCGGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGAC
CCGAGAGCTCGTGCGGGGCAAAGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAA
TCGGGGTGGTTGGATGCGGAGACGGGGCGGCAGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGG
GACCGACAAGGAGCTGAGCGACCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGG
AAGCAGTCAATTCAGTGGATCAGGTATCTCAGATGAAGACATCATCAACATTACTCTTCCTACTGGAGTCCCCATTCTTCTGGAATTGGA
TGAAAACCTGCGTGCTGTTGGGCCTCATCAGTTCCTGGGTGACCAAGAGGCGATCCAAGCAGCCATTAAGAAAGTAGAAGATCAAGGAAA
AGTGAAACAAGCTAAAAAATAGTCTTTCTCAACTGTTGGCTAAGAAGAAATGCAAAAGAAGTGGCATAGGAGTGTGTTATGGGTGCTGAA
CTCTCTCTCTTTTTCCCCGATTTTCCAGAGCTAGGCTGTGGAGTAGAGTTTGTATAGGTAACTAGGTAACTTATTGTGGCCCAGATAAGG
CTTTAGGATGCCTCAGTGCTTATGTCATAGCCTTATGAGTTAGCTTTCTTGCTAGCCCCCTAGTCGGTCACCAAACTAGTAACTAGTGGG
GCTTAATGAAGGTCATAAGTTTCTGAGATGGGAGAGCAACAAGTAGAGATGAAGTTAAAGGTATTTATCATTCAAGAAATCATTATTGAG
TCACCATTGACAGGCACTATTCTAATCAGTAGTTCACTTTAATATTTAATAAGATTTTCTGGGATAACAGTAAGGGATATTAGATAATAT
ACCGTATGTATTTATTACTAGTCTTTTCCTCTAGGAAAAGGGATACTTTGATAATTAAGGCCAGAGGCCCATTAGTTGAGAAAGTCACAG
ATATATTTCTCCAAGAAAGCCAACAACCACCACCACAATGACAGAAATGACAACAAGGCCCTTTAACTTGTCTTCTAGTTTAGAGACATC
CTTCATTTGACATTTAGTAGAATTCCTCTTTGGCCACAAGAATAAGCAGCAAATAAACAACTATGGCTGTTGAGGTTCTCATTTTGGTTT

>89697_89697_4_TCF12-BPGM_TCF12_chr15_57213296_ENST00000333725_BPGM_chr7_134363604_ENST00000393132_length(amino acids)=108AA_BP=49
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAI

--------------------------------------------------------------
>89697_89697_5_TCF12-BPGM_TCF12_chr15_57213296_ENST00000438423_BPGM_chr7_134363604_ENST00000344924_length(transcript)=1405nt_BP=444nt
GGCGCGGAGGGATCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTAT
TCGGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGC
AAAGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGG
AGACGGGGCGGCAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGG
ACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGGTATCT
CAGATGAAGACATCATCAACATTACTCTTCCTACTGGAGTCCCCATTCTTCTGGAATTGGATGAAAACCTGCGTGCTGTTGGGCCTCATC
AGTTCCTGGGTGACCAAGAGGCGATCCAAGCAGCCATTAAGAAAGTAGAAGATCAAGGAAAAGTGAAACAAGCTAAAAAATAGTCTTTCT
CAACTGTTGGCTAAGAAGAAATGCAAAAGAAGTGGCATAGGAGTGTGTTATGGGTGCTGAACTCTCTCTCTTTTTCCCCGATTTTCCAGA
GCTAGGCTGTGGAGTAGAGTTTGTATAGGTAACTAGGTAACTTATTGTGGCCCAGATAAGGCTTTAGGATGCCTCAGTGCTTATGTCATA
GCCTTATGAGTTAGCTTTCTTGCTAGCCCCCTAGTCGGTCACCAAACTAGTAACTAGTGGGGCTTAATGAAGGTCATAAGTTTCTGAGAT
GGGAGAGCAACAAGTAGAGATGAAGTTAAAGGTATTTATCATTCAAGAAATCATTATTGAGTCACCATTGACAGGCACTATTCTAATCAG
TAGTTCACTTTAATATTTAATAAGATTTTCTGGGATAACAGTAAGGGATATTAGATAATATACCGTATGTATTTATTACTAGTCTTTTCC
TCTAGGAAAAGGGATACTTTGATAATTAAGGCCAGAGGCCCATTAGTTGAGAAAGTCACAGATATATTTCTCCAAGAAAGCCAACAACCA
CCACCACAATGACAGAAATGACAACAAGGCCCTTTAACTTGTCTTCTAGTTTAGAGACATCCTTCATTTGACATTTAGTAGAATTCCTCT
TTGGCCACAAGAATAAGCAGCAAATAAACAACTATGGCTGTTGAGGTTCTCATTTTGGTTTGTTTTAATTTTTTGAACTTTGGGTACCTG

>89697_89697_5_TCF12-BPGM_TCF12_chr15_57213296_ENST00000438423_BPGM_chr7_134363604_ENST00000344924_length(amino acids)=120AA_BP=61
MDAETGRQKWPKMNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGISDEDIINITLPTGVPILLELDENLRAV

--------------------------------------------------------------
>89697_89697_6_TCF12-BPGM_TCF12_chr15_57213296_ENST00000438423_BPGM_chr7_134363604_ENST00000393132_length(transcript)=1405nt_BP=444nt
GGCGCGGAGGGATCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTAT
TCGGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGC
AAAGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGG
AGACGGGGCGGCAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGG
ACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGGTATCT
CAGATGAAGACATCATCAACATTACTCTTCCTACTGGAGTCCCCATTCTTCTGGAATTGGATGAAAACCTGCGTGCTGTTGGGCCTCATC
AGTTCCTGGGTGACCAAGAGGCGATCCAAGCAGCCATTAAGAAAGTAGAAGATCAAGGAAAAGTGAAACAAGCTAAAAAATAGTCTTTCT
CAACTGTTGGCTAAGAAGAAATGCAAAAGAAGTGGCATAGGAGTGTGTTATGGGTGCTGAACTCTCTCTCTTTTTCCCCGATTTTCCAGA
GCTAGGCTGTGGAGTAGAGTTTGTATAGGTAACTAGGTAACTTATTGTGGCCCAGATAAGGCTTTAGGATGCCTCAGTGCTTATGTCATA
GCCTTATGAGTTAGCTTTCTTGCTAGCCCCCTAGTCGGTCACCAAACTAGTAACTAGTGGGGCTTAATGAAGGTCATAAGTTTCTGAGAT
GGGAGAGCAACAAGTAGAGATGAAGTTAAAGGTATTTATCATTCAAGAAATCATTATTGAGTCACCATTGACAGGCACTATTCTAATCAG
TAGTTCACTTTAATATTTAATAAGATTTTCTGGGATAACAGTAAGGGATATTAGATAATATACCGTATGTATTTATTACTAGTCTTTTCC
TCTAGGAAAAGGGATACTTTGATAATTAAGGCCAGAGGCCCATTAGTTGAGAAAGTCACAGATATATTTCTCCAAGAAAGCCAACAACCA
CCACCACAATGACAGAAATGACAACAAGGCCCTTTAACTTGTCTTCTAGTTTAGAGACATCCTTCATTTGACATTTAGTAGAATTCCTCT
TTGGCCACAAGAATAAGCAGCAAATAAACAACTATGGCTGTTGAGGTTCTCATTTTGGTTTGTTTTAATTTTTTGAACTTTGGGTACCTG

>89697_89697_6_TCF12-BPGM_TCF12_chr15_57213296_ENST00000438423_BPGM_chr7_134363604_ENST00000393132_length(amino acids)=120AA_BP=61
MDAETGRQKWPKMNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGISDEDIINITLPTGVPILLELDENLRAV

--------------------------------------------------------------
>89697_89697_7_TCF12-BPGM_TCF12_chr15_57213296_ENST00000452095_BPGM_chr7_134363604_ENST00000344924_length(transcript)=1403nt_BP=442nt
TCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTATTCGGGGGGACCG
ACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGCAAAGTGAACCGA
GCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAGACGGGGCGGC
AGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGGAC
TTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGGTATCTCA
GATGAAGACATCATCAACATTACTCTTCCTACTGGAGTCCCCATTCTTCTGGAATTGGATGAAAACCTGCGTGCTGTTGGGCCTCATCAG
TTCCTGGGTGACCAAGAGGCGATCCAAGCAGCCATTAAGAAAGTAGAAGATCAAGGAAAAGTGAAACAAGCTAAAAAATAGTCTTTCTCA
ACTGTTGGCTAAGAAGAAATGCAAAAGAAGTGGCATAGGAGTGTGTTATGGGTGCTGAACTCTCTCTCTTTTTCCCCGATTTTCCAGAGC
TAGGCTGTGGAGTAGAGTTTGTATAGGTAACTAGGTAACTTATTGTGGCCCAGATAAGGCTTTAGGATGCCTCAGTGCTTATGTCATAGC
CTTATGAGTTAGCTTTCTTGCTAGCCCCCTAGTCGGTCACCAAACTAGTAACTAGTGGGGCTTAATGAAGGTCATAAGTTTCTGAGATGG
GAGAGCAACAAGTAGAGATGAAGTTAAAGGTATTTATCATTCAAGAAATCATTATTGAGTCACCATTGACAGGCACTATTCTAATCAGTA
GTTCACTTTAATATTTAATAAGATTTTCTGGGATAACAGTAAGGGATATTAGATAATATACCGTATGTATTTATTACTAGTCTTTTCCTC
TAGGAAAAGGGATACTTTGATAATTAAGGCCAGAGGCCCATTAGTTGAGAAAGTCACAGATATATTTCTCCAAGAAAGCCAACAACCACC
ACCACAATGACAGAAATGACAACAAGGCCCTTTAACTTGTCTTCTAGTTTAGAGACATCCTTCATTTGACATTTAGTAGAATTCCTCTTT
GGCCACAAGAATAAGCAGCAAATAAACAACTATGGCTGTTGAGGTTCTCATTTTGGTTTGTTTTAATTTTTTGAACTTTGGGTACCTGTA

>89697_89697_7_TCF12-BPGM_TCF12_chr15_57213296_ENST00000452095_BPGM_chr7_134363604_ENST00000344924_length(amino acids)=108AA_BP=49
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAI

--------------------------------------------------------------
>89697_89697_8_TCF12-BPGM_TCF12_chr15_57213296_ENST00000452095_BPGM_chr7_134363604_ENST00000393132_length(transcript)=1403nt_BP=442nt
TCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTATTCGGGGGGACCG
ACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGCAAAGTGAACCGA
GCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAGACGGGGCGGC
AGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGGAC
TTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGGTATCTCA
GATGAAGACATCATCAACATTACTCTTCCTACTGGAGTCCCCATTCTTCTGGAATTGGATGAAAACCTGCGTGCTGTTGGGCCTCATCAG
TTCCTGGGTGACCAAGAGGCGATCCAAGCAGCCATTAAGAAAGTAGAAGATCAAGGAAAAGTGAAACAAGCTAAAAAATAGTCTTTCTCA
ACTGTTGGCTAAGAAGAAATGCAAAAGAAGTGGCATAGGAGTGTGTTATGGGTGCTGAACTCTCTCTCTTTTTCCCCGATTTTCCAGAGC
TAGGCTGTGGAGTAGAGTTTGTATAGGTAACTAGGTAACTTATTGTGGCCCAGATAAGGCTTTAGGATGCCTCAGTGCTTATGTCATAGC
CTTATGAGTTAGCTTTCTTGCTAGCCCCCTAGTCGGTCACCAAACTAGTAACTAGTGGGGCTTAATGAAGGTCATAAGTTTCTGAGATGG
GAGAGCAACAAGTAGAGATGAAGTTAAAGGTATTTATCATTCAAGAAATCATTATTGAGTCACCATTGACAGGCACTATTCTAATCAGTA
GTTCACTTTAATATTTAATAAGATTTTCTGGGATAACAGTAAGGGATATTAGATAATATACCGTATGTATTTATTACTAGTCTTTTCCTC
TAGGAAAAGGGATACTTTGATAATTAAGGCCAGAGGCCCATTAGTTGAGAAAGTCACAGATATATTTCTCCAAGAAAGCCAACAACCACC
ACCACAATGACAGAAATGACAACAAGGCCCTTTAACTTGTCTTCTAGTTTAGAGACATCCTTCATTTGACATTTAGTAGAATTCCTCTTT
GGCCACAAGAATAAGCAGCAAATAAACAACTATGGCTGTTGAGGTTCTCATTTTGGTTTGTTTTAATTTTTTGAACTTTGGGTACCTGTA

>89697_89697_8_TCF12-BPGM_TCF12_chr15_57213296_ENST00000452095_BPGM_chr7_134363604_ENST00000393132_length(amino acids)=108AA_BP=49
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAI

--------------------------------------------------------------
>89697_89697_9_TCF12-BPGM_TCF12_chr15_57213296_ENST00000557843_BPGM_chr7_134363604_ENST00000344924_length(transcript)=1196nt_BP=235nt
GGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAGACGGGGCGGCAGAAGTGGCCGAAGATG
AATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTT
AATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGGTATCTCAGATGAAGACATCATCAACATTACTCTT
CCTACTGGAGTCCCCATTCTTCTGGAATTGGATGAAAACCTGCGTGCTGTTGGGCCTCATCAGTTCCTGGGTGACCAAGAGGCGATCCAA
GCAGCCATTAAGAAAGTAGAAGATCAAGGAAAAGTGAAACAAGCTAAAAAATAGTCTTTCTCAACTGTTGGCTAAGAAGAAATGCAAAAG
AAGTGGCATAGGAGTGTGTTATGGGTGCTGAACTCTCTCTCTTTTTCCCCGATTTTCCAGAGCTAGGCTGTGGAGTAGAGTTTGTATAGG
TAACTAGGTAACTTATTGTGGCCCAGATAAGGCTTTAGGATGCCTCAGTGCTTATGTCATAGCCTTATGAGTTAGCTTTCTTGCTAGCCC
CCTAGTCGGTCACCAAACTAGTAACTAGTGGGGCTTAATGAAGGTCATAAGTTTCTGAGATGGGAGAGCAACAAGTAGAGATGAAGTTAA
AGGTATTTATCATTCAAGAAATCATTATTGAGTCACCATTGACAGGCACTATTCTAATCAGTAGTTCACTTTAATATTTAATAAGATTTT
CTGGGATAACAGTAAGGGATATTAGATAATATACCGTATGTATTTATTACTAGTCTTTTCCTCTAGGAAAAGGGATACTTTGATAATTAA
GGCCAGAGGCCCATTAGTTGAGAAAGTCACAGATATATTTCTCCAAGAAAGCCAACAACCACCACCACAATGACAGAAATGACAACAAGG
CCCTTTAACTTGTCTTCTAGTTTAGAGACATCCTTCATTTGACATTTAGTAGAATTCCTCTTTGGCCACAAGAATAAGCAGCAAATAAAC
AACTATGGCTGTTGAGGTTCTCATTTTGGTTTGTTTTAATTTTTTGAACTTTGGGTACCTGTAATTAGTTTAAAAATAAAGTTCCTGATA

>89697_89697_9_TCF12-BPGM_TCF12_chr15_57213296_ENST00000557843_BPGM_chr7_134363604_ENST00000344924_length(amino acids)=120AA_BP=61
MDAETGRQKWPKMNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGISDEDIINITLPTGVPILLELDENLRAV

--------------------------------------------------------------
>89697_89697_10_TCF12-BPGM_TCF12_chr15_57213296_ENST00000557843_BPGM_chr7_134363604_ENST00000393132_length(transcript)=1196nt_BP=235nt
GGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAGACGGGGCGGCAGAAGTGGCCGAAGATG
AATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTT
AATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGGTATCTCAGATGAAGACATCATCAACATTACTCTT
CCTACTGGAGTCCCCATTCTTCTGGAATTGGATGAAAACCTGCGTGCTGTTGGGCCTCATCAGTTCCTGGGTGACCAAGAGGCGATCCAA
GCAGCCATTAAGAAAGTAGAAGATCAAGGAAAAGTGAAACAAGCTAAAAAATAGTCTTTCTCAACTGTTGGCTAAGAAGAAATGCAAAAG
AAGTGGCATAGGAGTGTGTTATGGGTGCTGAACTCTCTCTCTTTTTCCCCGATTTTCCAGAGCTAGGCTGTGGAGTAGAGTTTGTATAGG
TAACTAGGTAACTTATTGTGGCCCAGATAAGGCTTTAGGATGCCTCAGTGCTTATGTCATAGCCTTATGAGTTAGCTTTCTTGCTAGCCC
CCTAGTCGGTCACCAAACTAGTAACTAGTGGGGCTTAATGAAGGTCATAAGTTTCTGAGATGGGAGAGCAACAAGTAGAGATGAAGTTAA
AGGTATTTATCATTCAAGAAATCATTATTGAGTCACCATTGACAGGCACTATTCTAATCAGTAGTTCACTTTAATATTTAATAAGATTTT
CTGGGATAACAGTAAGGGATATTAGATAATATACCGTATGTATTTATTACTAGTCTTTTCCTCTAGGAAAAGGGATACTTTGATAATTAA
GGCCAGAGGCCCATTAGTTGAGAAAGTCACAGATATATTTCTCCAAGAAAGCCAACAACCACCACCACAATGACAGAAATGACAACAAGG
CCCTTTAACTTGTCTTCTAGTTTAGAGACATCCTTCATTTGACATTTAGTAGAATTCCTCTTTGGCCACAAGAATAAGCAGCAAATAAAC
AACTATGGCTGTTGAGGTTCTCATTTTGGTTTGTTTTAATTTTTTGAACTTTGGGTACCTGTAATTAGTTTAAAAATAAAGTTCCTGATA

>89697_89697_10_TCF12-BPGM_TCF12_chr15_57213296_ENST00000557843_BPGM_chr7_134363604_ENST00000393132_length(amino acids)=120AA_BP=61
MDAETGRQKWPKMNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGISDEDIINITLPTGVPILLELDENLRAV

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for TCF12-BPGM


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneTCF12chr15:57213296chr7:134363604ENST00000267811+320182_19649.3333333333333361821.3333333333333RUNX1T1
HgeneTCF12chr15:57213296chr7:134363604ENST00000333725+321182_19649.3333333333333361420.0RUNX1T1
HgeneTCF12chr15:57213296chr7:134363604ENST00000343827+113182_19601254.6666666666667RUNX1T1
HgeneTCF12chr15:57213296chr7:134363604ENST00000438423+321182_19649.3333333333333361398.3333333333333RUNX1T1
HgeneTCF12chr15:57213296chr7:134363604ENST00000557843+320182_19649.3333333333333361301.0RUNX1T1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for TCF12-BPGM


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for TCF12-BPGM


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource