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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TCF12-NPAS1 (FusionGDB2 ID:89715)

Fusion Gene Summary for TCF12-NPAS1

check button Fusion gene summary
Fusion gene informationFusion gene name: TCF12-NPAS1
Fusion gene ID: 89715
HgeneTgene
Gene symbol

TCF12

NPAS1

Gene ID

6938

4861

Gene nametranscription factor 12neuronal PAS domain protein 1
SynonymsCRS3|HEB|HTF4|HsT17266|TCF-12|bHLHb20|p64MOP5|PASD5|bHLHe11
Cytomap

15q21.3

19q13.32

Type of geneprotein-codingprotein-coding
Descriptiontranscription factor 12DNA-binding protein HTF4E-box-binding proteinclass B basic helix-loop-helix protein 20helix-loop-helix transcription factor 4transcription factor HTF-4neuronal PAS domain-containing protein 1PAS domain-containing protein 5basic-helix-loop-helix-PAS protein MOP5class E basic helix-loop-helix protein 11member of PAS protein 5member of PAS superfamily 5neuronal PAS1
Modification date2020031320200313
UniProtAcc.

Q99742

Ensembl transtripts involved in fusion geneENST00000267811, ENST00000333725, 
ENST00000438423, ENST00000452095, 
ENST00000557843, ENST00000343827, 
ENST00000537840, ENST00000543579, 
ENST00000559703, ENST00000559710, 
ENST00000560764, 		ENST00000439365, 
ENST00000449844, ENST00000602189, 
ENST00000602212, 
Fusion gene scores* DoF score29 X 19 X 12=66129 X 4 X 5=180
# samples 3212
** MAII scorelog2(32/6612*10)=-4.36894291440495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/180*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TCF12 [Title/Abstract] AND NPAS1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTCF12(57213296)-NPAS1(47542294), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTCF12

GO:0045944

positive regulation of transcription by RNA polymerase II

11802795


check buttonFusion gene breakpoints across TCF12 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NPAS1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-EJ-A8FO-01ATCF12chr15

57213296

-NPAS1chr19

47542294

+
ChimerDB4PRADTCGA-EJ-A8FO-01ATCF12chr15

57213296

+NPAS1chr19

47542294

+


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Fusion Gene ORF analysis for TCF12-NPAS1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000267811ENST00000439365TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000267811ENST00000449844TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000267811ENST00000602189TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000267811ENST00000602212TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000333725ENST00000439365TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000333725ENST00000449844TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000333725ENST00000602189TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000333725ENST00000602212TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000438423ENST00000439365TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000438423ENST00000449844TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000438423ENST00000602189TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000438423ENST00000602212TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000452095ENST00000439365TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000452095ENST00000449844TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000452095ENST00000602189TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000452095ENST00000602212TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000557843ENST00000439365TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000557843ENST00000449844TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000557843ENST00000602189TCF12chr15

57213296

+NPAS1chr19

47542294

+
In-frameENST00000557843ENST00000602212TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000343827ENST00000439365TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000343827ENST00000449844TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000343827ENST00000602189TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000343827ENST00000602212TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000537840ENST00000439365TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000537840ENST00000449844TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000537840ENST00000602189TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000537840ENST00000602212TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000543579ENST00000439365TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000543579ENST00000449844TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000543579ENST00000602189TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000543579ENST00000602212TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000559703ENST00000439365TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000559703ENST00000449844TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000559703ENST00000602189TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000559703ENST00000602212TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000559710ENST00000439365TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000559710ENST00000449844TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000559710ENST00000602189TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000559710ENST00000602212TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000560764ENST00000439365TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000560764ENST00000449844TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000560764ENST00000602189TCF12chr15

57213296

+NPAS1chr19

47542294

+
intron-3CDSENST00000560764ENST00000602212TCF12chr15

57213296

+NPAS1chr19

47542294

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000438423TCF12chr1557213296+ENST00000602212NPAS1chr1947542294+16534442601528422
ENST00000438423TCF12chr1557213296+ENST00000602189NPAS1chr1947542294+16084442601531423
ENST00000438423TCF12chr1557213296+ENST00000449844NPAS1chr1947542294+16374442601528422
ENST00000438423TCF12chr1557213296+ENST00000439365NPAS1chr1947542294+15894441532720270
ENST00000267811TCF12chr1557213296+ENST00000602212NPAS1chr1947542294+16614523041536410
ENST00000267811TCF12chr1557213296+ENST00000602189NPAS1chr1947542294+16164523041539411
ENST00000267811TCF12chr1557213296+ENST00000449844NPAS1chr1947542294+16454523041536410
ENST00000267811TCF12chr1557213296+ENST00000439365NPAS1chr1947542294+15974521540728270
ENST00000452095TCF12chr1557213296+ENST00000602212NPAS1chr1947542294+16514422941526410
ENST00000452095TCF12chr1557213296+ENST00000602189NPAS1chr1947542294+16064422941529411
ENST00000452095TCF12chr1557213296+ENST00000449844NPAS1chr1947542294+16354422941526410
ENST00000452095TCF12chr1557213296+ENST00000439365NPAS1chr1947542294+15874421530718270
ENST00000333725TCF12chr1557213296+ENST00000602212NPAS1chr1947542294+15923832351467410
ENST00000333725TCF12chr1557213296+ENST00000602189NPAS1chr1947542294+15473832351470411
ENST00000333725TCF12chr1557213296+ENST00000449844NPAS1chr1947542294+15763832351467410
ENST00000333725TCF12chr1557213296+ENST00000439365NPAS1chr1947542294+15283836411420259
ENST00000557843TCF12chr1557213296+ENST00000602212NPAS1chr1947542294+1444235511319422
ENST00000557843TCF12chr1557213296+ENST00000602189NPAS1chr1947542294+1399235511322423
ENST00000557843TCF12chr1557213296+ENST00000449844NPAS1chr1947542294+1428235511319422
ENST00000557843TCF12chr1557213296+ENST00000439365NPAS1chr1947542294+13802354931272259

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000438423ENST00000602212TCF12chr1557213296+NPAS1chr1947542294+0.169747830.8302522
ENST00000438423ENST00000602189TCF12chr1557213296+NPAS1chr1947542294+0.159792070.840208
ENST00000438423ENST00000449844TCF12chr1557213296+NPAS1chr1947542294+0.17399590.826004
ENST00000438423ENST00000439365TCF12chr1557213296+NPAS1chr1947542294+0.62493750.37506256
ENST00000267811ENST00000602212TCF12chr1557213296+NPAS1chr1947542294+0.170939620.8290604
ENST00000267811ENST00000602189TCF12chr1557213296+NPAS1chr1947542294+0.161485550.8385144
ENST00000267811ENST00000449844TCF12chr1557213296+NPAS1chr1947542294+0.175208360.82479167
ENST00000267811ENST00000439365TCF12chr1557213296+NPAS1chr1947542294+0.61929170.38070828
ENST00000452095ENST00000602212TCF12chr1557213296+NPAS1chr1947542294+0.175772470.8242276
ENST00000452095ENST00000602189TCF12chr1557213296+NPAS1chr1947542294+0.166285590.8337144
ENST00000452095ENST00000449844TCF12chr1557213296+NPAS1chr1947542294+0.18013640.81986356
ENST00000452095ENST00000439365TCF12chr1557213296+NPAS1chr1947542294+0.65936440.3406356
ENST00000333725ENST00000602212TCF12chr1557213296+NPAS1chr1947542294+0.173103530.8268964
ENST00000333725ENST00000602189TCF12chr1557213296+NPAS1chr1947542294+0.162729490.8372705
ENST00000333725ENST00000449844TCF12chr1557213296+NPAS1chr1947542294+0.17707160.8229284
ENST00000333725ENST00000439365TCF12chr1557213296+NPAS1chr1947542294+0.59806550.40193453
ENST00000557843ENST00000602212TCF12chr1557213296+NPAS1chr1947542294+0.138311650.8616884
ENST00000557843ENST00000602189TCF12chr1557213296+NPAS1chr1947542294+0.133227680.86677235
ENST00000557843ENST00000449844TCF12chr1557213296+NPAS1chr1947542294+0.14298380.85701615
ENST00000557843ENST00000439365TCF12chr1557213296+NPAS1chr1947542294+0.499778960.5002211

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Fusion Genomic Features for TCF12-NPAS1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TCF12chr1557213296+NPAS1chr1947542293+1.34E-070.9999999
TCF12chr1557213296+NPAS1chr1947542293+1.34E-070.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for TCF12-NPAS1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:57213296/chr19:47542294)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.NPAS1

Q99742

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level (By similarity). Forms a heterodimer that binds core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) leading to transcriptional repression on its target gene TH (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:P97459}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTCF12chr15:57213296chr19:47542294ENST00000267811+32019_27491821.3333333333333MotifNote=9aaTAD
HgeneTCF12chr15:57213296chr19:47542294ENST00000333725+32119_27491420.0MotifNote=9aaTAD
HgeneTCF12chr15:57213296chr19:47542294ENST00000438423+32119_27491398.3333333333333MotifNote=9aaTAD
HgeneTCF12chr15:57213296chr19:47542294ENST00000557843+32019_27491301.0MotifNote=9aaTAD
TgeneNPAS1chr15:57213296chr19:47542294ENST00000449844411293_359229591.0DomainPAS 2
TgeneNPAS1chr15:57213296chr19:47542294ENST00000449844411365_408229591.0DomainNote=PAC
TgeneNPAS1chr15:57213296chr19:47542294ENST00000602212512293_359229591.0DomainPAS 2
TgeneNPAS1chr15:57213296chr19:47542294ENST00000602212512365_408229591.0DomainNote=PAC

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTCF12chr15:57213296chr19:47542294ENST00000267811+320577_630491821.3333333333333DomainbHLH
HgeneTCF12chr15:57213296chr19:47542294ENST00000333725+321577_630491420.0DomainbHLH
HgeneTCF12chr15:57213296chr19:47542294ENST00000343827+113577_63001254.6666666666667DomainbHLH
HgeneTCF12chr15:57213296chr19:47542294ENST00000438423+321577_630491398.3333333333333DomainbHLH
HgeneTCF12chr15:57213296chr19:47542294ENST00000557843+320577_630491301.0DomainbHLH
HgeneTCF12chr15:57213296chr19:47542294ENST00000343827+11319_2701254.6666666666667MotifNote=9aaTAD
HgeneTCF12chr15:57213296chr19:47542294ENST00000267811+320119_140491821.3333333333333RegionNote=Leucine-zipper
HgeneTCF12chr15:57213296chr19:47542294ENST00000267811+320632_655491821.3333333333333RegionNote=Class A specific domain
HgeneTCF12chr15:57213296chr19:47542294ENST00000333725+321119_140491420.0RegionNote=Leucine-zipper
HgeneTCF12chr15:57213296chr19:47542294ENST00000333725+321632_655491420.0RegionNote=Class A specific domain
HgeneTCF12chr15:57213296chr19:47542294ENST00000343827+113119_14001254.6666666666667RegionNote=Leucine-zipper
HgeneTCF12chr15:57213296chr19:47542294ENST00000343827+113632_65501254.6666666666667RegionNote=Class A specific domain
HgeneTCF12chr15:57213296chr19:47542294ENST00000438423+321119_140491398.3333333333333RegionNote=Leucine-zipper
HgeneTCF12chr15:57213296chr19:47542294ENST00000438423+321632_655491398.3333333333333RegionNote=Class A specific domain
HgeneTCF12chr15:57213296chr19:47542294ENST00000557843+320119_140491301.0RegionNote=Leucine-zipper
HgeneTCF12chr15:57213296chr19:47542294ENST00000557843+320632_655491301.0RegionNote=Class A specific domain
TgeneNPAS1chr15:57213296chr19:47542294ENST00000449844411211_222229591.0Compositional biasNote=Poly-Ser
TgeneNPAS1chr15:57213296chr19:47542294ENST00000602212512211_222229591.0Compositional biasNote=Poly-Ser
TgeneNPAS1chr15:57213296chr19:47542294ENST00000449844411135_207229591.0DomainPAS 1
TgeneNPAS1chr15:57213296chr19:47542294ENST0000044984441145_98229591.0DomainbHLH
TgeneNPAS1chr15:57213296chr19:47542294ENST00000602212512135_207229591.0DomainPAS 1
TgeneNPAS1chr15:57213296chr19:47542294ENST0000060221251245_98229591.0DomainbHLH


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Fusion Gene Sequence for TCF12-NPAS1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>89715_89715_1_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000267811_NPAS1_chr19_47542294_ENST00000439365_length(transcript)=1597nt_BP=452nt
CGCGGAGGGATCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTATTC
GGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGCAA
AGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAG
ACGGGGCGGCAGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGA
CCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATC
AGAGGCCAGCCTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGG
GCTGCACGTCAAGGCCTCAGGGTACAAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCACAC
GTTGCCCCCGGCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTGTGA
GAGCAGAGTCAGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCACGAG
GATCCGCCAGAGCCACGTGGACTCGTGCCGGGGGCTTCGTGTGGCTGCAGTCTGTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGG
AGCACCATGTGCTTTGGGTCAGCCACGTGCTCAGCCAAGCCGAGGGTGGCCAAACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGG
CCTGTGAGGAGGCATCCAGCCCGGGGCCAGAGCCCACAGAGCCGGAGCCTCCGACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGG
CCCCCCAGACCCAGGGCAAACGCATCAAAGTGGAGCCCGGCCCGAGGGAAACCAAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCA
GCCACCCGGCCACACCGAGGCCCGAGTTCACCTCTGTCATCCGGGCAGGGGTCCTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGC
CTCCCGGGGACCCCCCGCCCACCCTCCTGCACGCGGGCTTCCTGCCGCCGGTGGTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACG
GCCCCGCGGAGCTGGGCCTGGTGTACCCGCACCTGCAGAGGCTGGGTCCGGGCCCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCC
TGCCCTACCCGGGGCCCGCGGGCACCAGGCTGCCGCGGAAGGGGGACTGAGGACTGGCAGAGCTGCCGGCGCCGGACCCTGCGACAACCG

>89715_89715_1_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000267811_NPAS1_chr19_47542294_ENST00000439365_length(amino acids)=270AA_BP=
MGDPGCRRVRRRQLCQSSVPLPRQPGARGPRVGQAQGRVKGLRERGARTQPLQVRVHQAQLRGAVADGAGCAQAPHHRRQEARVQEGGRG
VPGRRQAPWPHRILLQDPCPDDRGELGPRCGRVAGGILVATVLGAFGFPRAGLHFDAFALGLGGLVLRWGSLLPFRRRLRLCGLWPRAGC
LLTGHAGWKLEGIQRSLATLGLAEHVADPKHMVLPGALPAPSHCGHRLQPHEAPGTSPRGSGGSSWRPVRGQTGSSCGPPALRAPGPCGR

--------------------------------------------------------------
>89715_89715_2_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000267811_NPAS1_chr19_47542294_ENST00000449844_length(transcript)=1645nt_BP=452nt
CGCGGAGGGATCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTATTC
GGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGCAA
AGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAG
ACGGGGCGGCAGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGA
CCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATC
AGAGGCCAGCCTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGG
GCTGCACGTCAAGGCCTCAGGGTACAAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCACAC
GTTGCCCCCGGCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTGTGA
GAGCAGAGTCAGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCACGAG
GATCCGCCAGAGCCACGTGGACTTGCTGGACAAGGGTCAGGTGATGACTGGTTACTACCGTTGGCTGCAGCGTGCCGGGGGCTTCGTGTG
GCTGCAGTCTGTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGGAGCACCATGTGCTTTGGGTCAGCCACGTGCTCAGCCAAGCCGA
GGGTGGCCAAACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGGCCTGTGAGGAGGCATCCAGCCCGGGGCCAGAGCCCACAGAGCC
GGAGCCTCCGACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGGCCCCCCAGACCCAGGGCAAACGCATCAAAGTGGAGCCCGGCCC
GAGGGAAACCAAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCAGCCACCCGGCCACACCGAGGCCCGAGTTCACCTCTGTCATCCG
GGCAGGGGTCCTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGCCTCCCGGGGACCCCCCGCCCACCCTCCTGCACGCGGGCTTCCT
GCCGCCGGTGGTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACGGCCCCGCGGAGCTGGGCCTGGTGTACCCGCACCTGCAGAGGCT
GGGTCCGGGCCCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCCTGCCCTACCCGGGGCCCGCGGGCACCAGGCTGCCGCGGAAGGG
GGACTGAGGACTGGCAGAGCTGCCGGCGCCGGACCCTGCGACAACCGGGGTCCCCCAGGACAGTAGGCCCGGCTCTGCCCGTAGCCCTGA

>89715_89715_2_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000267811_NPAS1_chr19_47542294_ENST00000449844_length(amino acids)=410AA_BP=49
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSEASLTKVPPSSLVQERSFFVRMKSTLTKRGLHVKASGYKVI
HVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDATRIRQSHVDLLDK
GQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTEPEPPTEGKQAAP
AENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAGFLPPVVRGLCTPG

--------------------------------------------------------------
>89715_89715_3_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000267811_NPAS1_chr19_47542294_ENST00000602189_length(transcript)=1616nt_BP=452nt
CGCGGAGGGATCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTATTC
GGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGCAA
AGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAG
ACGGGGCGGCAGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGA
CCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATC
AGAGGCCAGCCTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGG
GCTGCACGTCAAGGCCTCAGGGTACAAGCAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCA
CACGTTGCCCCCGGCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTG
TGAGAGCAGAGTCAGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCAC
GAGGATCCGCCAGAGCCACGTGGACTTGCTGGACAAGGGTCAGGTGATGACTGGTTACTACCGTTGGCTGCAGCGTGCCGGGGGCTTCGT
GTGGCTGCAGTCTGTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGGAGCACCATGTGCTTTGGGTCAGCCACGTGCTCAGCCAAGC
CGAGGGTGGCCAAACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGGCCTGTGAGGAGGCATCCAGCCCGGGGCCAGAGCCCACAGA
GCCGGAGCCTCCGACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGGCCCCCCAGACCCAGGGCAAACGCATCAAAGTGGAGCCCGG
CCCGAGGGAAACCAAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCAGCCACCCGGCCACACCGAGGCCCGAGTTCACCTCTGTCAT
CCGGGCAGGGGTCCTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGCCTCCCGGGGACCCCCCGCCCACCCTCCTGCACGCGGGCTT
CCTGCCGCCGGTGGTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACGGCCCCGCGGAGCTGGGCCTGGTGTACCCGCACCTGCAGAG
GCTGGGTCCGGGCCCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCCTGCCCTACCCGGGGCCCGCGGGCACCAGGCTGCCGCGGAA

>89715_89715_3_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000267811_NPAS1_chr19_47542294_ENST00000602189_length(amino acids)=411AA_BP=49
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSEASLTKVPPSSLVQERSFFVRMKSTLTKRGLHVKASGYKQV
IHVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDATRIRQSHVDLLD
KGQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTEPEPPTEGKQAA
PAENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAGFLPPVVRGLCTP

--------------------------------------------------------------
>89715_89715_4_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000267811_NPAS1_chr19_47542294_ENST00000602212_length(transcript)=1661nt_BP=452nt
CGCGGAGGGATCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTATTC
GGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGCAA
AGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAG
ACGGGGCGGCAGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGA
CCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATC
AGAGGCCAGCCTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGG
GCTGCACGTCAAGGCCTCAGGGTACAAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCACAC
GTTGCCCCCGGCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTGTGA
GAGCAGAGTCAGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCACGAG
GATCCGCCAGAGCCACGTGGACTTGCTGGACAAGGGTCAGGTGATGACTGGTTACTACCGTTGGCTGCAGCGTGCCGGGGGCTTCGTGTG
GCTGCAGTCTGTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGGAGCACCATGTGCTTTGGGTCAGCCACGTGCTCAGCCAAGCCGA
GGGTGGCCAAACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGGCCTGTGAGGAGGCATCCAGCCCGGGGCCAGAGCCCACAGAGCC
GGAGCCTCCGACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGGCCCCCCAGACCCAGGGCAAACGCATCAAAGTGGAGCCCGGCCC
GAGGGAAACCAAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCAGCCACCCGGCCACACCGAGGCCCGAGTTCACCTCTGTCATCCG
GGCAGGGGTCCTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGCCTCCCGGGGACCCCCCGCCCACCCTCCTGCACGCGGGCTTCCT
GCCGCCGGTGGTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACGGCCCCGCGGAGCTGGGCCTGGTGTACCCGCACCTGCAGAGGCT
GGGTCCGGGCCCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCCTGCCCTACCCGGGGCCCGCGGGCACCAGGCTGCCGCGGAAGGG
GGACTGAGGACTGGCAGAGCTGCCGGCGCCGGACCCTGCGACAACCGGGGTCCCCCAGGACAGTAGGCCCGGCTCTGCCCGTAGCCCTGA

>89715_89715_4_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000267811_NPAS1_chr19_47542294_ENST00000602212_length(amino acids)=410AA_BP=49
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSEASLTKVPPSSLVQERSFFVRMKSTLTKRGLHVKASGYKVI
HVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDATRIRQSHVDLLDK
GQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTEPEPPTEGKQAAP
AENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAGFLPPVVRGLCTPG

--------------------------------------------------------------
>89715_89715_5_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000333725_NPAS1_chr19_47542294_ENST00000439365_length(transcript)=1528nt_BP=383nt
AGAGACCCACAAGTTCTATTCGGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGAC
CCGAGAGCTCGTGCGGGGCAAAGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAA
TCGGGGTGGTTGGATGCGGAGACGGGGCGGCAGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGG
GACCGACAAGGAGCTGAGCGACCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGG
AAGCAGTCAATTCAGTGGATCAGAGGCCAGCCTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAA
ATCCACGCTCACCAAGAGGGGGCTGCACGTCAAGGCCTCAGGGTACAAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGG
CCTTGTGGCCCTCGGGCACACGTTGCCCCCGGCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCTGGG
TCTCACCATCCTTGCTTGTGAGAGCAGAGTCAGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGT
CCACGGACAGGACGCCACGAGGATCCGCCAGAGCCACGTGGACTCGTGCCGGGGGCTTCGTGTGGCTGCAGTCTGTGGCCACAGTGGCTG
GGAGCGGGAAGAGCCCCGGGGAGCACCATGTGCTTTGGGTCAGCCACGTGCTCAGCCAAGCCGAGGGTGGCCAAACTCCTTTGGATGCCT
TCCAGCTTCCAGCCAGCGTGGCCTGTGAGGAGGCATCCAGCCCGGGGCCAGAGCCCACAGAGCCGGAGCCTCCGACGGAAGGGAAGCAGG
CTGCCCCAGCGGAGAACGAGGCCCCCCAGACCCAGGGCAAACGCATCAAAGTGGAGCCCGGCCCGAGGGAAACCAAAGGCTCCGAGGACA
GTGGCGACGAGGATCCCTCCAGCCACCCGGCCACACCGAGGCCCGAGTTCACCTCTGTCATCCGGGCAGGGGTCCTGAAGCAGGATCCGG
TGCGGCCATGGGGCCTGGCGCCTCCCGGGGACCCCCCGCCCACCCTCCTGCACGCGGGCTTCCTGCCGCCGGTGGTGCGGGGCCTGTGCA
CACCCGGCACCATCCGCTACGGCCCCGCGGAGCTGGGCCTGGTGTACCCGCACCTGCAGAGGCTGGGTCCGGGCCCCGCGCTCCCGGAGG
CCTTTTACCCGCCCCTGGGCCTGCCCTACCCGGGGCCCGCGGGCACCAGGCTGCCGCGGAAGGGGGACTGAGGACTGGCAGAGCTGCCGG

>89715_89715_5_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000333725_NPAS1_chr19_47542294_ENST00000439365_length(amino acids)=259AA_BP=
MLVRAESATTWTWGPQSWWAAAATSLSTDRTPRGSARATWTRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLP
ASVACEEASSPGPEPTEPEPPTEGKQAAPAENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPW

--------------------------------------------------------------
>89715_89715_6_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000333725_NPAS1_chr19_47542294_ENST00000449844_length(transcript)=1576nt_BP=383nt
AGAGACCCACAAGTTCTATTCGGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGAC
CCGAGAGCTCGTGCGGGGCAAAGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAA
TCGGGGTGGTTGGATGCGGAGACGGGGCGGCAGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGG
GACCGACAAGGAGCTGAGCGACCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGG
AAGCAGTCAATTCAGTGGATCAGAGGCCAGCCTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAA
ATCCACGCTCACCAAGAGGGGGCTGCACGTCAAGGCCTCAGGGTACAAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGG
CCTTGTGGCCCTCGGGCACACGTTGCCCCCGGCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCTGGG
TCTCACCATCCTTGCTTGTGAGAGCAGAGTCAGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGT
CCACGGACAGGACGCCACGAGGATCCGCCAGAGCCACGTGGACTTGCTGGACAAGGGTCAGGTGATGACTGGTTACTACCGTTGGCTGCA
GCGTGCCGGGGGCTTCGTGTGGCTGCAGTCTGTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGGAGCACCATGTGCTTTGGGTCAG
CCACGTGCTCAGCCAAGCCGAGGGTGGCCAAACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGGCCTGTGAGGAGGCATCCAGCCC
GGGGCCAGAGCCCACAGAGCCGGAGCCTCCGACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGGCCCCCCAGACCCAGGGCAAACG
CATCAAAGTGGAGCCCGGCCCGAGGGAAACCAAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCAGCCACCCGGCCACACCGAGGCC
CGAGTTCACCTCTGTCATCCGGGCAGGGGTCCTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGCCTCCCGGGGACCCCCCGCCCAC
CCTCCTGCACGCGGGCTTCCTGCCGCCGGTGGTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACGGCCCCGCGGAGCTGGGCCTGGT
GTACCCGCACCTGCAGAGGCTGGGTCCGGGCCCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCCTGCCCTACCCGGGGCCCGCGGG
CACCAGGCTGCCGCGGAAGGGGGACTGAGGACTGGCAGAGCTGCCGGCGCCGGACCCTGCGACAACCGGGGTCCCCCAGGACAGTAGGCC

>89715_89715_6_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000333725_NPAS1_chr19_47542294_ENST00000449844_length(amino acids)=410AA_BP=49
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSEASLTKVPPSSLVQERSFFVRMKSTLTKRGLHVKASGYKVI
HVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDATRIRQSHVDLLDK
GQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTEPEPPTEGKQAAP
AENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAGFLPPVVRGLCTPG

--------------------------------------------------------------
>89715_89715_7_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000333725_NPAS1_chr19_47542294_ENST00000602189_length(transcript)=1547nt_BP=383nt
AGAGACCCACAAGTTCTATTCGGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGAC
CCGAGAGCTCGTGCGGGGCAAAGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAA
TCGGGGTGGTTGGATGCGGAGACGGGGCGGCAGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGG
GACCGACAAGGAGCTGAGCGACCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGG
AAGCAGTCAATTCAGTGGATCAGAGGCCAGCCTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAA
ATCCACGCTCACCAAGAGGGGGCTGCACGTCAAGGCCTCAGGGTACAAGCAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCT
GGGCCTTGTGGCCCTCGGGCACACGTTGCCCCCGGCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCT
GGGTCTCACCATCCTTGCTTGTGAGAGCAGAGTCAGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTT
TGTCCACGGACAGGACGCCACGAGGATCCGCCAGAGCCACGTGGACTTGCTGGACAAGGGTCAGGTGATGACTGGTTACTACCGTTGGCT
GCAGCGTGCCGGGGGCTTCGTGTGGCTGCAGTCTGTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGGAGCACCATGTGCTTTGGGT
CAGCCACGTGCTCAGCCAAGCCGAGGGTGGCCAAACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGGCCTGTGAGGAGGCATCCAG
CCCGGGGCCAGAGCCCACAGAGCCGGAGCCTCCGACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGGCCCCCCAGACCCAGGGCAA
ACGCATCAAAGTGGAGCCCGGCCCGAGGGAAACCAAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCAGCCACCCGGCCACACCGAG
GCCCGAGTTCACCTCTGTCATCCGGGCAGGGGTCCTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGCCTCCCGGGGACCCCCCGCC
CACCCTCCTGCACGCGGGCTTCCTGCCGCCGGTGGTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACGGCCCCGCGGAGCTGGGCCT
GGTGTACCCGCACCTGCAGAGGCTGGGTCCGGGCCCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCCTGCCCTACCCGGGGCCCGC
GGGCACCAGGCTGCCGCGGAAGGGGGACTGAGGACTGGCAGAGCTGCCGGCGCCGGACCCTGCGACAACCGGGGTCCCCCAGGACAGTAG

>89715_89715_7_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000333725_NPAS1_chr19_47542294_ENST00000602189_length(amino acids)=411AA_BP=49
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSEASLTKVPPSSLVQERSFFVRMKSTLTKRGLHVKASGYKQV
IHVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDATRIRQSHVDLLD
KGQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTEPEPPTEGKQAA
PAENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAGFLPPVVRGLCTP

--------------------------------------------------------------
>89715_89715_8_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000333725_NPAS1_chr19_47542294_ENST00000602212_length(transcript)=1592nt_BP=383nt
AGAGACCCACAAGTTCTATTCGGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGAC
CCGAGAGCTCGTGCGGGGCAAAGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAA
TCGGGGTGGTTGGATGCGGAGACGGGGCGGCAGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGG
GACCGACAAGGAGCTGAGCGACCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGG
AAGCAGTCAATTCAGTGGATCAGAGGCCAGCCTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAA
ATCCACGCTCACCAAGAGGGGGCTGCACGTCAAGGCCTCAGGGTACAAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGG
CCTTGTGGCCCTCGGGCACACGTTGCCCCCGGCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCTGGG
TCTCACCATCCTTGCTTGTGAGAGCAGAGTCAGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGT
CCACGGACAGGACGCCACGAGGATCCGCCAGAGCCACGTGGACTTGCTGGACAAGGGTCAGGTGATGACTGGTTACTACCGTTGGCTGCA
GCGTGCCGGGGGCTTCGTGTGGCTGCAGTCTGTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGGAGCACCATGTGCTTTGGGTCAG
CCACGTGCTCAGCCAAGCCGAGGGTGGCCAAACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGGCCTGTGAGGAGGCATCCAGCCC
GGGGCCAGAGCCCACAGAGCCGGAGCCTCCGACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGGCCCCCCAGACCCAGGGCAAACG
CATCAAAGTGGAGCCCGGCCCGAGGGAAACCAAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCAGCCACCCGGCCACACCGAGGCC
CGAGTTCACCTCTGTCATCCGGGCAGGGGTCCTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGCCTCCCGGGGACCCCCCGCCCAC
CCTCCTGCACGCGGGCTTCCTGCCGCCGGTGGTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACGGCCCCGCGGAGCTGGGCCTGGT
GTACCCGCACCTGCAGAGGCTGGGTCCGGGCCCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCCTGCCCTACCCGGGGCCCGCGGG
CACCAGGCTGCCGCGGAAGGGGGACTGAGGACTGGCAGAGCTGCCGGCGCCGGACCCTGCGACAACCGGGGTCCCCCAGGACAGTAGGCC

>89715_89715_8_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000333725_NPAS1_chr19_47542294_ENST00000602212_length(amino acids)=410AA_BP=49
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSEASLTKVPPSSLVQERSFFVRMKSTLTKRGLHVKASGYKVI
HVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDATRIRQSHVDLLDK
GQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTEPEPPTEGKQAAP
AENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAGFLPPVVRGLCTPG

--------------------------------------------------------------
>89715_89715_9_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000438423_NPAS1_chr19_47542294_ENST00000439365_length(transcript)=1589nt_BP=444nt
GGCGCGGAGGGATCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTAT
TCGGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGC
AAAGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGG
AGACGGGGCGGCAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGG
ACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGAGGCCA
GCCTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGGGCTGCACG
TCAAGGCCTCAGGGTACAAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCACACGTTGCCCC
CGGCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTGTGAGAGCAGAG
TCAGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCACGAGGATCCGCC
AGAGCCACGTGGACTCGTGCCGGGGGCTTCGTGTGGCTGCAGTCTGTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGGAGCACCAT
GTGCTTTGGGTCAGCCACGTGCTCAGCCAAGCCGAGGGTGGCCAAACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGGCCTGTGAG
GAGGCATCCAGCCCGGGGCCAGAGCCCACAGAGCCGGAGCCTCCGACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGGCCCCCCAG
ACCCAGGGCAAACGCATCAAAGTGGAGCCCGGCCCGAGGGAAACCAAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCAGCCACCCG
GCCACACCGAGGCCCGAGTTCACCTCTGTCATCCGGGCAGGGGTCCTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGCCTCCCGGG
GACCCCCCGCCCACCCTCCTGCACGCGGGCTTCCTGCCGCCGGTGGTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACGGCCCCGCG
GAGCTGGGCCTGGTGTACCCGCACCTGCAGAGGCTGGGTCCGGGCCCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCCTGCCCTAC
CCGGGGCCCGCGGGCACCAGGCTGCCGCGGAAGGGGGACTGAGGACTGGCAGAGCTGCCGGCGCCGGACCCTGCGACAACCGGGGTCCCC

>89715_89715_9_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000438423_NPAS1_chr19_47542294_ENST00000439365_length(amino acids)=270AA_BP=
MGDPGCRRVRRRQLCQSSVPLPRQPGARGPRVGQAQGRVKGLRERGARTQPLQVRVHQAQLRGAVADGAGCAQAPHHRRQEARVQEGGRG
VPGRRQAPWPHRILLQDPCPDDRGELGPRCGRVAGGILVATVLGAFGFPRAGLHFDAFALGLGGLVLRWGSLLPFRRRLRLCGLWPRAGC
LLTGHAGWKLEGIQRSLATLGLAEHVADPKHMVLPGALPAPSHCGHRLQPHEAPGTSPRGSGGSSWRPVRGQTGSSCGPPALRAPGPCGR

--------------------------------------------------------------
>89715_89715_10_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000438423_NPAS1_chr19_47542294_ENST00000449844_length(transcript)=1637nt_BP=444nt
GGCGCGGAGGGATCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTAT
TCGGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGC
AAAGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGG
AGACGGGGCGGCAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGG
ACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGAGGCCA
GCCTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGGGCTGCACG
TCAAGGCCTCAGGGTACAAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCACACGTTGCCCC
CGGCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTGTGAGAGCAGAG
TCAGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCACGAGGATCCGCC
AGAGCCACGTGGACTTGCTGGACAAGGGTCAGGTGATGACTGGTTACTACCGTTGGCTGCAGCGTGCCGGGGGCTTCGTGTGGCTGCAGT
CTGTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGGAGCACCATGTGCTTTGGGTCAGCCACGTGCTCAGCCAAGCCGAGGGTGGCC
AAACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGGCCTGTGAGGAGGCATCCAGCCCGGGGCCAGAGCCCACAGAGCCGGAGCCTC
CGACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGGCCCCCCAGACCCAGGGCAAACGCATCAAAGTGGAGCCCGGCCCGAGGGAAA
CCAAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCAGCCACCCGGCCACACCGAGGCCCGAGTTCACCTCTGTCATCCGGGCAGGGG
TCCTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGCCTCCCGGGGACCCCCCGCCCACCCTCCTGCACGCGGGCTTCCTGCCGCCGG
TGGTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACGGCCCCGCGGAGCTGGGCCTGGTGTACCCGCACCTGCAGAGGCTGGGTCCGG
GCCCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCCTGCCCTACCCGGGGCCCGCGGGCACCAGGCTGCCGCGGAAGGGGGACTGAG
GACTGGCAGAGCTGCCGGCGCCGGACCCTGCGACAACCGGGGTCCCCCAGGACAGTAGGCCCGGCTCTGCCCGTAGCCCTGAGAATTAAA

>89715_89715_10_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000438423_NPAS1_chr19_47542294_ENST00000449844_length(amino acids)=422AA_BP=61
MDAETGRQKWPKMNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSEASLTKVPPSSLVQERSFFVRMKSTLTKR
GLHVKASGYKVIHVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDAT
RIRQSHVDLLDKGQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTE
PEPPTEGKQAAPAENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAGF

--------------------------------------------------------------
>89715_89715_11_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000438423_NPAS1_chr19_47542294_ENST00000602189_length(transcript)=1608nt_BP=444nt
GGCGCGGAGGGATCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTAT
TCGGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGC
AAAGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGG
AGACGGGGCGGCAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGG
ACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGAGGCCA
GCCTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGGGCTGCACG
TCAAGGCCTCAGGGTACAAGCAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCACACGTTGC
CCCCGGCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTGTGAGAGCA
GAGTCAGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCACGAGGATCC
GCCAGAGCCACGTGGACTTGCTGGACAAGGGTCAGGTGATGACTGGTTACTACCGTTGGCTGCAGCGTGCCGGGGGCTTCGTGTGGCTGC
AGTCTGTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGGAGCACCATGTGCTTTGGGTCAGCCACGTGCTCAGCCAAGCCGAGGGTG
GCCAAACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGGCCTGTGAGGAGGCATCCAGCCCGGGGCCAGAGCCCACAGAGCCGGAGC
CTCCGACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGGCCCCCCAGACCCAGGGCAAACGCATCAAAGTGGAGCCCGGCCCGAGGG
AAACCAAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCAGCCACCCGGCCACACCGAGGCCCGAGTTCACCTCTGTCATCCGGGCAG
GGGTCCTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGCCTCCCGGGGACCCCCCGCCCACCCTCCTGCACGCGGGCTTCCTGCCGC
CGGTGGTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACGGCCCCGCGGAGCTGGGCCTGGTGTACCCGCACCTGCAGAGGCTGGGTC
CGGGCCCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCCTGCCCTACCCGGGGCCCGCGGGCACCAGGCTGCCGCGGAAGGGGGACT

>89715_89715_11_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000438423_NPAS1_chr19_47542294_ENST00000602189_length(amino acids)=423AA_BP=61
MDAETGRQKWPKMNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSEASLTKVPPSSLVQERSFFVRMKSTLTKR
GLHVKASGYKQVIHVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDA
TRIRQSHVDLLDKGQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPT
EPEPPTEGKQAAPAENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAG

--------------------------------------------------------------
>89715_89715_12_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000438423_NPAS1_chr19_47542294_ENST00000602212_length(transcript)=1653nt_BP=444nt
GGCGCGGAGGGATCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTAT
TCGGGGGGACCGACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGC
AAAGTGAACCGAGCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGG
AGACGGGGCGGCAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGG
ACTTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGAGGCCA
GCCTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGGGCTGCACG
TCAAGGCCTCAGGGTACAAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCACACGTTGCCCC
CGGCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTGTGAGAGCAGAG
TCAGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCACGAGGATCCGCC
AGAGCCACGTGGACTTGCTGGACAAGGGTCAGGTGATGACTGGTTACTACCGTTGGCTGCAGCGTGCCGGGGGCTTCGTGTGGCTGCAGT
CTGTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGGAGCACCATGTGCTTTGGGTCAGCCACGTGCTCAGCCAAGCCGAGGGTGGCC
AAACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGGCCTGTGAGGAGGCATCCAGCCCGGGGCCAGAGCCCACAGAGCCGGAGCCTC
CGACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGGCCCCCCAGACCCAGGGCAAACGCATCAAAGTGGAGCCCGGCCCGAGGGAAA
CCAAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCAGCCACCCGGCCACACCGAGGCCCGAGTTCACCTCTGTCATCCGGGCAGGGG
TCCTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGCCTCCCGGGGACCCCCCGCCCACCCTCCTGCACGCGGGCTTCCTGCCGCCGG
TGGTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACGGCCCCGCGGAGCTGGGCCTGGTGTACCCGCACCTGCAGAGGCTGGGTCCGG
GCCCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCCTGCCCTACCCGGGGCCCGCGGGCACCAGGCTGCCGCGGAAGGGGGACTGAG
GACTGGCAGAGCTGCCGGCGCCGGACCCTGCGACAACCGGGGTCCCCCAGGACAGTAGGCCCGGCTCTGCCCGTAGCCCTGAGAATTAAA

>89715_89715_12_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000438423_NPAS1_chr19_47542294_ENST00000602212_length(amino acids)=422AA_BP=61
MDAETGRQKWPKMNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSEASLTKVPPSSLVQERSFFVRMKSTLTKR
GLHVKASGYKVIHVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDAT
RIRQSHVDLLDKGQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTE
PEPPTEGKQAAPAENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAGF

--------------------------------------------------------------
>89715_89715_13_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000452095_NPAS1_chr19_47542294_ENST00000439365_length(transcript)=1587nt_BP=442nt
TCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTATTCGGGGGGACCG
ACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGCAAAGTGAACCGA
GCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAGACGGGGCGGC
AGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGGAC
TTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGAGGCCAGC
CTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGGGCTGCACGTC
AAGGCCTCAGGGTACAAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCACACGTTGCCCCCG
GCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTGTGAGAGCAGAGTC
AGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCACGAGGATCCGCCAG
AGCCACGTGGACTCGTGCCGGGGGCTTCGTGTGGCTGCAGTCTGTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGGAGCACCATGT
GCTTTGGGTCAGCCACGTGCTCAGCCAAGCCGAGGGTGGCCAAACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGGCCTGTGAGGA
GGCATCCAGCCCGGGGCCAGAGCCCACAGAGCCGGAGCCTCCGACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGGCCCCCCAGAC
CCAGGGCAAACGCATCAAAGTGGAGCCCGGCCCGAGGGAAACCAAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCAGCCACCCGGC
CACACCGAGGCCCGAGTTCACCTCTGTCATCCGGGCAGGGGTCCTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGCCTCCCGGGGA
CCCCCCGCCCACCCTCCTGCACGCGGGCTTCCTGCCGCCGGTGGTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACGGCCCCGCGGA
GCTGGGCCTGGTGTACCCGCACCTGCAGAGGCTGGGTCCGGGCCCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCCTGCCCTACCC
GGGGCCCGCGGGCACCAGGCTGCCGCGGAAGGGGGACTGAGGACTGGCAGAGCTGCCGGCGCCGGACCCTGCGACAACCGGGGTCCCCCA

>89715_89715_13_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000452095_NPAS1_chr19_47542294_ENST00000439365_length(amino acids)=270AA_BP=
MGDPGCRRVRRRQLCQSSVPLPRQPGARGPRVGQAQGRVKGLRERGARTQPLQVRVHQAQLRGAVADGAGCAQAPHHRRQEARVQEGGRG
VPGRRQAPWPHRILLQDPCPDDRGELGPRCGRVAGGILVATVLGAFGFPRAGLHFDAFALGLGGLVLRWGSLLPFRRRLRLCGLWPRAGC
LLTGHAGWKLEGIQRSLATLGLAEHVADPKHMVLPGALPAPSHCGHRLQPHEAPGTSPRGSGGSSWRPVRGQTGSSCGPPALRAPGPCGR

--------------------------------------------------------------
>89715_89715_14_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000452095_NPAS1_chr19_47542294_ENST00000449844_length(transcript)=1635nt_BP=442nt
TCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTATTCGGGGGGACCG
ACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGCAAAGTGAACCGA
GCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAGACGGGGCGGC
AGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGGAC
TTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGAGGCCAGC
CTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGGGCTGCACGTC
AAGGCCTCAGGGTACAAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCACACGTTGCCCCCG
GCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTGTGAGAGCAGAGTC
AGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCACGAGGATCCGCCAG
AGCCACGTGGACTTGCTGGACAAGGGTCAGGTGATGACTGGTTACTACCGTTGGCTGCAGCGTGCCGGGGGCTTCGTGTGGCTGCAGTCT
GTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGGAGCACCATGTGCTTTGGGTCAGCCACGTGCTCAGCCAAGCCGAGGGTGGCCAA
ACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGGCCTGTGAGGAGGCATCCAGCCCGGGGCCAGAGCCCACAGAGCCGGAGCCTCCG
ACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGGCCCCCCAGACCCAGGGCAAACGCATCAAAGTGGAGCCCGGCCCGAGGGAAACC
AAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCAGCCACCCGGCCACACCGAGGCCCGAGTTCACCTCTGTCATCCGGGCAGGGGTC
CTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGCCTCCCGGGGACCCCCCGCCCACCCTCCTGCACGCGGGCTTCCTGCCGCCGGTG
GTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACGGCCCCGCGGAGCTGGGCCTGGTGTACCCGCACCTGCAGAGGCTGGGTCCGGGC
CCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCCTGCCCTACCCGGGGCCCGCGGGCACCAGGCTGCCGCGGAAGGGGGACTGAGGA
CTGGCAGAGCTGCCGGCGCCGGACCCTGCGACAACCGGGGTCCCCCAGGACAGTAGGCCCGGCTCTGCCCGTAGCCCTGAGAATTAAACG

>89715_89715_14_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000452095_NPAS1_chr19_47542294_ENST00000449844_length(amino acids)=410AA_BP=49
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSEASLTKVPPSSLVQERSFFVRMKSTLTKRGLHVKASGYKVI
HVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDATRIRQSHVDLLDK
GQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTEPEPPTEGKQAAP
AENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAGFLPPVVRGLCTPG

--------------------------------------------------------------
>89715_89715_15_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000452095_NPAS1_chr19_47542294_ENST00000602189_length(transcript)=1606nt_BP=442nt
TCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTATTCGGGGGGACCG
ACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGCAAAGTGAACCGA
GCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAGACGGGGCGGC
AGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGGAC
TTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGAGGCCAGC
CTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGGGCTGCACGTC
AAGGCCTCAGGGTACAAGCAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCACACGTTGCCC
CCGGCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTGTGAGAGCAGA
GTCAGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCACGAGGATCCGC
CAGAGCCACGTGGACTTGCTGGACAAGGGTCAGGTGATGACTGGTTACTACCGTTGGCTGCAGCGTGCCGGGGGCTTCGTGTGGCTGCAG
TCTGTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGGAGCACCATGTGCTTTGGGTCAGCCACGTGCTCAGCCAAGCCGAGGGTGGC
CAAACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGGCCTGTGAGGAGGCATCCAGCCCGGGGCCAGAGCCCACAGAGCCGGAGCCT
CCGACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGGCCCCCCAGACCCAGGGCAAACGCATCAAAGTGGAGCCCGGCCCGAGGGAA
ACCAAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCAGCCACCCGGCCACACCGAGGCCCGAGTTCACCTCTGTCATCCGGGCAGGG
GTCCTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGCCTCCCGGGGACCCCCCGCCCACCCTCCTGCACGCGGGCTTCCTGCCGCCG
GTGGTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACGGCCCCGCGGAGCTGGGCCTGGTGTACCCGCACCTGCAGAGGCTGGGTCCG
GGCCCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCCTGCCCTACCCGGGGCCCGCGGGCACCAGGCTGCCGCGGAAGGGGGACTGA

>89715_89715_15_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000452095_NPAS1_chr19_47542294_ENST00000602189_length(amino acids)=411AA_BP=49
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSEASLTKVPPSSLVQERSFFVRMKSTLTKRGLHVKASGYKQV
IHVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDATRIRQSHVDLLD
KGQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTEPEPPTEGKQAA
PAENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAGFLPPVVRGLCTP

--------------------------------------------------------------
>89715_89715_16_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000452095_NPAS1_chr19_47542294_ENST00000602212_length(transcript)=1651nt_BP=442nt
TCCGGAGGCGAGCCGAGCGCGGTGGTGAGGCCGCCTCAGCGAAAAAAATGTCCGCCTGAAGAGACCCACAAGTTCTATTCGGGGGGACCG
ACAGCCCGCCCCGGGAGGAAGGGGCGGCCAGGCCCGAAAGCCGCCTCCCCCTCCCAGACCCGAGAGCTCGTGCGGGGCAAAGTGAACCGA
GCCGCTGGGCGGTGCAAGGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAGACGGGGCGGC
AGGACCTGCTAGAAGTGGCCGAAGATGAATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGGAC
TTCAGTGCGATGTTTTCCCCACCTGTTAATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGAGGCCAGC
CTCACCAAGGTGCCCCCCTCCTCCCTGGTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGGGCTGCACGTC
AAGGCCTCAGGGTACAAGGTCATCCACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCACACGTTGCCCCCG
GCCCCCCTGGCTGAGCTGCCACTCCATGGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTGTGAGAGCAGAGTC
AGCGACCACATGGACCTGGGGCCCTCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCACGAGGATCCGCCAG
AGCCACGTGGACTTGCTGGACAAGGGTCAGGTGATGACTGGTTACTACCGTTGGCTGCAGCGTGCCGGGGGCTTCGTGTGGCTGCAGTCT
GTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGGAGCACCATGTGCTTTGGGTCAGCCACGTGCTCAGCCAAGCCGAGGGTGGCCAA
ACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGGCCTGTGAGGAGGCATCCAGCCCGGGGCCAGAGCCCACAGAGCCGGAGCCTCCG
ACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGGCCCCCCAGACCCAGGGCAAACGCATCAAAGTGGAGCCCGGCCCGAGGGAAACC
AAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCAGCCACCCGGCCACACCGAGGCCCGAGTTCACCTCTGTCATCCGGGCAGGGGTC
CTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGCCTCCCGGGGACCCCCCGCCCACCCTCCTGCACGCGGGCTTCCTGCCGCCGGTG
GTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACGGCCCCGCGGAGCTGGGCCTGGTGTACCCGCACCTGCAGAGGCTGGGTCCGGGC
CCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCCTGCCCTACCCGGGGCCCGCGGGCACCAGGCTGCCGCGGAAGGGGGACTGAGGA
CTGGCAGAGCTGCCGGCGCCGGACCCTGCGACAACCGGGGTCCCCCAGGACAGTAGGCCCGGCTCTGCCCGTAGCCCTGAGAATTAAACG

>89715_89715_16_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000452095_NPAS1_chr19_47542294_ENST00000602212_length(amino acids)=410AA_BP=49
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSEASLTKVPPSSLVQERSFFVRMKSTLTKRGLHVKASGYKVI
HVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDATRIRQSHVDLLDK
GQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTEPEPPTEGKQAAP
AENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAGFLPPVVRGLCTPG

--------------------------------------------------------------
>89715_89715_17_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000557843_NPAS1_chr19_47542294_ENST00000439365_length(transcript)=1380nt_BP=235nt
GGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAGACGGGGCGGCAGAAGTGGCCGAAGATG
AATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTT
AATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGAGGCCAGCCTCACCAAGGTGCCCCCCTCCTCCCTG
GTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGGGCTGCACGTCAAGGCCTCAGGGTACAAGGTCATCCAC
GTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCACACGTTGCCCCCGGCCCCCCTGGCTGAGCTGCCACTCCAT
GGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTGTGAGAGCAGAGTCAGCGACCACATGGACCTGGGGCCCTCA
GAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCACGAGGATCCGCCAGAGCCACGTGGACTCGTGCCGGGGGCTT
CGTGTGGCTGCAGTCTGTGGCCACAGTGGCTGGGAGCGGGAAGAGCCCCGGGGAGCACCATGTGCTTTGGGTCAGCCACGTGCTCAGCCA
AGCCGAGGGTGGCCAAACTCCTTTGGATGCCTTCCAGCTTCCAGCCAGCGTGGCCTGTGAGGAGGCATCCAGCCCGGGGCCAGAGCCCAC
AGAGCCGGAGCCTCCGACGGAAGGGAAGCAGGCTGCCCCAGCGGAGAACGAGGCCCCCCAGACCCAGGGCAAACGCATCAAAGTGGAGCC
CGGCCCGAGGGAAACCAAAGGCTCCGAGGACAGTGGCGACGAGGATCCCTCCAGCCACCCGGCCACACCGAGGCCCGAGTTCACCTCTGT
CATCCGGGCAGGGGTCCTGAAGCAGGATCCGGTGCGGCCATGGGGCCTGGCGCCTCCCGGGGACCCCCCGCCCACCCTCCTGCACGCGGG
CTTCCTGCCGCCGGTGGTGCGGGGCCTGTGCACACCCGGCACCATCCGCTACGGCCCCGCGGAGCTGGGCCTGGTGTACCCGCACCTGCA
GAGGCTGGGTCCGGGCCCCGCGCTCCCGGAGGCCTTTTACCCGCCCCTGGGCCTGCCCTACCCGGGGCCCGCGGGCACCAGGCTGCCGCG
GAAGGGGGACTGAGGACTGGCAGAGCTGCCGGCGCCGGACCCTGCGACAACCGGGGTCCCCCAGGACAGTAGGCCCGGCTCTGCCCGTAG

>89715_89715_17_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000557843_NPAS1_chr19_47542294_ENST00000439365_length(amino acids)=259AA_BP=
MLVRAESATTWTWGPQSWWAAAATSLSTDRTPRGSARATWTRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLP
ASVACEEASSPGPEPTEPEPPTEGKQAAPAENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPW

--------------------------------------------------------------
>89715_89715_18_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000557843_NPAS1_chr19_47542294_ENST00000449844_length(transcript)=1428nt_BP=235nt
GGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAGACGGGGCGGCAGAAGTGGCCGAAGATG
AATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTT
AATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGAGGCCAGCCTCACCAAGGTGCCCCCCTCCTCCCTG
GTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGGGCTGCACGTCAAGGCCTCAGGGTACAAGGTCATCCAC
GTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCACACGTTGCCCCCGGCCCCCCTGGCTGAGCTGCCACTCCAT
GGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTGTGAGAGCAGAGTCAGCGACCACATGGACCTGGGGCCCTCA
GAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCACGAGGATCCGCCAGAGCCACGTGGACTTGCTGGACAAGGGT
CAGGTGATGACTGGTTACTACCGTTGGCTGCAGCGTGCCGGGGGCTTCGTGTGGCTGCAGTCTGTGGCCACAGTGGCTGGGAGCGGGAAG
AGCCCCGGGGAGCACCATGTGCTTTGGGTCAGCCACGTGCTCAGCCAAGCCGAGGGTGGCCAAACTCCTTTGGATGCCTTCCAGCTTCCA
GCCAGCGTGGCCTGTGAGGAGGCATCCAGCCCGGGGCCAGAGCCCACAGAGCCGGAGCCTCCGACGGAAGGGAAGCAGGCTGCCCCAGCG
GAGAACGAGGCCCCCCAGACCCAGGGCAAACGCATCAAAGTGGAGCCCGGCCCGAGGGAAACCAAAGGCTCCGAGGACAGTGGCGACGAG
GATCCCTCCAGCCACCCGGCCACACCGAGGCCCGAGTTCACCTCTGTCATCCGGGCAGGGGTCCTGAAGCAGGATCCGGTGCGGCCATGG
GGCCTGGCGCCTCCCGGGGACCCCCCGCCCACCCTCCTGCACGCGGGCTTCCTGCCGCCGGTGGTGCGGGGCCTGTGCACACCCGGCACC
ATCCGCTACGGCCCCGCGGAGCTGGGCCTGGTGTACCCGCACCTGCAGAGGCTGGGTCCGGGCCCCGCGCTCCCGGAGGCCTTTTACCCG
CCCCTGGGCCTGCCCTACCCGGGGCCCGCGGGCACCAGGCTGCCGCGGAAGGGGGACTGAGGACTGGCAGAGCTGCCGGCGCCGGACCCT

>89715_89715_18_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000557843_NPAS1_chr19_47542294_ENST00000449844_length(amino acids)=422AA_BP=61
MDAETGRQKWPKMNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSEASLTKVPPSSLVQERSFFVRMKSTLTKR
GLHVKASGYKVIHVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDAT
RIRQSHVDLLDKGQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTE
PEPPTEGKQAAPAENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAGF

--------------------------------------------------------------
>89715_89715_19_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000557843_NPAS1_chr19_47542294_ENST00000602189_length(transcript)=1399nt_BP=235nt
GGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAGACGGGGCGGCAGAAGTGGCCGAAGATG
AATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTT
AATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGAGGCCAGCCTCACCAAGGTGCCCCCCTCCTCCCTG
GTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGGGCTGCACGTCAAGGCCTCAGGGTACAAGCAGGTCATC
CACGTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCACACGTTGCCCCCGGCCCCCCTGGCTGAGCTGCCACTC
CATGGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTGTGAGAGCAGAGTCAGCGACCACATGGACCTGGGGCCC
TCAGAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCACGAGGATCCGCCAGAGCCACGTGGACTTGCTGGACAAG
GGTCAGGTGATGACTGGTTACTACCGTTGGCTGCAGCGTGCCGGGGGCTTCGTGTGGCTGCAGTCTGTGGCCACAGTGGCTGGGAGCGGG
AAGAGCCCCGGGGAGCACCATGTGCTTTGGGTCAGCCACGTGCTCAGCCAAGCCGAGGGTGGCCAAACTCCTTTGGATGCCTTCCAGCTT
CCAGCCAGCGTGGCCTGTGAGGAGGCATCCAGCCCGGGGCCAGAGCCCACAGAGCCGGAGCCTCCGACGGAAGGGAAGCAGGCTGCCCCA
GCGGAGAACGAGGCCCCCCAGACCCAGGGCAAACGCATCAAAGTGGAGCCCGGCCCGAGGGAAACCAAAGGCTCCGAGGACAGTGGCGAC
GAGGATCCCTCCAGCCACCCGGCCACACCGAGGCCCGAGTTCACCTCTGTCATCCGGGCAGGGGTCCTGAAGCAGGATCCGGTGCGGCCA
TGGGGCCTGGCGCCTCCCGGGGACCCCCCGCCCACCCTCCTGCACGCGGGCTTCCTGCCGCCGGTGGTGCGGGGCCTGTGCACACCCGGC
ACCATCCGCTACGGCCCCGCGGAGCTGGGCCTGGTGTACCCGCACCTGCAGAGGCTGGGTCCGGGCCCCGCGCTCCCGGAGGCCTTTTAC
CCGCCCCTGGGCCTGCCCTACCCGGGGCCCGCGGGCACCAGGCTGCCGCGGAAGGGGGACTGAGGACTGGCAGAGCTGCCGGCGCCGGAC

>89715_89715_19_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000557843_NPAS1_chr19_47542294_ENST00000602189_length(amino acids)=423AA_BP=61
MDAETGRQKWPKMNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSEASLTKVPPSSLVQERSFFVRMKSTLTKR
GLHVKASGYKQVIHVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDA
TRIRQSHVDLLDKGQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPT
EPEPPTEGKQAAPAENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAG

--------------------------------------------------------------
>89715_89715_20_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000557843_NPAS1_chr19_47542294_ENST00000602212_length(transcript)=1444nt_BP=235nt
GGGGAAGCCCAAGCCCGTTCTCCCGGCCAAAGTGAACTTTAATCGGGGTGGTTGGATGCGGAGACGGGGCGGCAGAAGTGGCCGAAGATG
AATCCCCAGCAACAACGCATGGCCGCTATAGGGACCGACAAGGAGCTGAGCGACCTACTGGACTTCAGTGCGATGTTTTCCCCACCTGTT
AATAGTGGGAAAACTAGACCAACTACACTGGGAAGCAGTCAATTCAGTGGATCAGAGGCCAGCCTCACCAAGGTGCCCCCCTCCTCCCTG
GTCCAGGAGCGCTCCTTCTTTGTCCGCATGAAATCCACGCTCACCAAGAGGGGGCTGCACGTCAAGGCCTCAGGGTACAAGGTCATCCAC
GTGACTGGGCGCCTTCGGGCCCACGCCCTGGGCCTTGTGGCCCTCGGGCACACGTTGCCCCCGGCCCCCCTGGCTGAGCTGCCACTCCAT
GGACACATGATCGTCTTCCGTCTCAGCCTGGGTCTCACCATCCTTGCTTGTGAGAGCAGAGTCAGCGACCACATGGACCTGGGGCCCTCA
GAGCTGGTGGGCCGCAGCTGCTACCAGTTTGTCCACGGACAGGACGCCACGAGGATCCGCCAGAGCCACGTGGACTTGCTGGACAAGGGT
CAGGTGATGACTGGTTACTACCGTTGGCTGCAGCGTGCCGGGGGCTTCGTGTGGCTGCAGTCTGTGGCCACAGTGGCTGGGAGCGGGAAG
AGCCCCGGGGAGCACCATGTGCTTTGGGTCAGCCACGTGCTCAGCCAAGCCGAGGGTGGCCAAACTCCTTTGGATGCCTTCCAGCTTCCA
GCCAGCGTGGCCTGTGAGGAGGCATCCAGCCCGGGGCCAGAGCCCACAGAGCCGGAGCCTCCGACGGAAGGGAAGCAGGCTGCCCCAGCG
GAGAACGAGGCCCCCCAGACCCAGGGCAAACGCATCAAAGTGGAGCCCGGCCCGAGGGAAACCAAAGGCTCCGAGGACAGTGGCGACGAG
GATCCCTCCAGCCACCCGGCCACACCGAGGCCCGAGTTCACCTCTGTCATCCGGGCAGGGGTCCTGAAGCAGGATCCGGTGCGGCCATGG
GGCCTGGCGCCTCCCGGGGACCCCCCGCCCACCCTCCTGCACGCGGGCTTCCTGCCGCCGGTGGTGCGGGGCCTGTGCACACCCGGCACC
ATCCGCTACGGCCCCGCGGAGCTGGGCCTGGTGTACCCGCACCTGCAGAGGCTGGGTCCGGGCCCCGCGCTCCCGGAGGCCTTTTACCCG
CCCCTGGGCCTGCCCTACCCGGGGCCCGCGGGCACCAGGCTGCCGCGGAAGGGGGACTGAGGACTGGCAGAGCTGCCGGCGCCGGACCCT
GCGACAACCGGGGTCCCCCAGGACAGTAGGCCCGGCTCTGCCCGTAGCCCTGAGAATTAAACGCCGGCTCTCCCTGCAGTGGTTTGGGCT

>89715_89715_20_TCF12-NPAS1_TCF12_chr15_57213296_ENST00000557843_NPAS1_chr19_47542294_ENST00000602212_length(amino acids)=422AA_BP=61
MDAETGRQKWPKMNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSEASLTKVPPSSLVQERSFFVRMKSTLTKR
GLHVKASGYKVIHVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDAT
RIRQSHVDLLDKGQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTE
PEPPTEGKQAAPAENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAGF

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TCF12-NPAS1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneTCF12chr15:57213296chr19:47542294ENST00000267811+320182_19649.3333333333333361821.3333333333333RUNX1T1
HgeneTCF12chr15:57213296chr19:47542294ENST00000333725+321182_19649.3333333333333361420.0RUNX1T1
HgeneTCF12chr15:57213296chr19:47542294ENST00000343827+113182_19601254.6666666666667RUNX1T1
HgeneTCF12chr15:57213296chr19:47542294ENST00000438423+321182_19649.3333333333333361398.3333333333333RUNX1T1
HgeneTCF12chr15:57213296chr19:47542294ENST00000557843+320182_19649.3333333333333361301.0RUNX1T1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TCF12-NPAS1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TCF12-NPAS1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource