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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TCF25-ZNF276 (FusionGDB2 ID:89759)

Fusion Gene Summary for TCF25-ZNF276

check button Fusion gene summary
Fusion gene informationFusion gene name: TCF25-ZNF276
Fusion gene ID: 89759
HgeneTgene
Gene symbol

TCF25

ZNF276

Gene ID

22980

92822

Gene nametranscription factor 25zinc finger protein 276
SynonymsFKSG26|Hulp1|NULP1|PRO2620|hKIAA1049CENP-Z|CENPZ|ZADT|ZFP276|ZNF477
Cytomap

16q24.3

16q24.3

Type of geneprotein-codingprotein-coding
Descriptiontranscription factor 25TCF-25nuclear localized protein 1transcription factor 25 (basic helix-loop-helix)zinc finger protein 276centromere protein Zzinc finger protein 276 homologzinc finger protein 477zinc finger, AD-type
Modification date2020031320200320
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000263346, ENST00000263347, 
ENST00000563406, 		ENST00000289816, 
ENST00000443381, ENST00000446326, 
ENST00000568064, 
Fusion gene scores* DoF score9 X 12 X 8=8647 X 7 X 5=245
# samples 127
** MAII scorelog2(12/864*10)=-2.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/245*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TCF25 [Title/Abstract] AND ZNF276 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTCF25(89973730)-ZNF276(89799710), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTCF25

GO:0000122

negative regulation of transcription by RNA polymerase II

16574069


check buttonFusion gene breakpoints across TCF25 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZNF276 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4COADTCGA-D5-6541-01ATCF25chr16

89973730

+ZNF276chr16

89799710

+


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Fusion Gene ORF analysis for TCF25-ZNF276

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000263346ENST00000289816TCF25chr16

89973730

+ZNF276chr16

89799710

+
In-frameENST00000263346ENST00000443381TCF25chr16

89973730

+ZNF276chr16

89799710

+
In-frameENST00000263346ENST00000446326TCF25chr16

89973730

+ZNF276chr16

89799710

+
In-frameENST00000263346ENST00000568064TCF25chr16

89973730

+ZNF276chr16

89799710

+
In-frameENST00000263347ENST00000289816TCF25chr16

89973730

+ZNF276chr16

89799710

+
In-frameENST00000263347ENST00000443381TCF25chr16

89973730

+ZNF276chr16

89799710

+
In-frameENST00000263347ENST00000446326TCF25chr16

89973730

+ZNF276chr16

89799710

+
In-frameENST00000263347ENST00000568064TCF25chr16

89973730

+ZNF276chr16

89799710

+
intron-3CDSENST00000563406ENST00000289816TCF25chr16

89973730

+ZNF276chr16

89799710

+
intron-3CDSENST00000563406ENST00000443381TCF25chr16

89973730

+ZNF276chr16

89799710

+
intron-3CDSENST00000563406ENST00000446326TCF25chr16

89973730

+ZNF276chr16

89799710

+
intron-3CDSENST00000563406ENST00000568064TCF25chr16

89973730

+ZNF276chr16

89799710

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000263346TCF25chr1689973730+ENST00000446326ZNF276chr1689799710+25661855562530824
ENST00000263346TCF25chr1689973730+ENST00000289816ZNF276chr1689799710+51881855562530824
ENST00000263346TCF25chr1689973730+ENST00000568064ZNF276chr1689799710+28751855562263735
ENST00000263346TCF25chr1689973730+ENST00000443381ZNF276chr1689799710+28561855562530824
ENST00000263347TCF25chr1689973730+ENST00000446326ZNF276chr1689799710+20841373602048662
ENST00000263347TCF25chr1689973730+ENST00000289816ZNF276chr1689799710+47061373602048662
ENST00000263347TCF25chr1689973730+ENST00000568064ZNF276chr1689799710+23931373601781573
ENST00000263347TCF25chr1689973730+ENST00000443381ZNF276chr1689799710+23741373602048662

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000263346ENST00000446326TCF25chr1689973730+ZNF276chr1689799710+0.0121353490.9878647
ENST00000263346ENST00000289816TCF25chr1689973730+ZNF276chr1689799710+0.0029787290.99702126
ENST00000263346ENST00000568064TCF25chr1689973730+ZNF276chr1689799710+0.0102551580.98974484
ENST00000263346ENST00000443381TCF25chr1689973730+ZNF276chr1689799710+0.0067203210.99327964
ENST00000263347ENST00000446326TCF25chr1689973730+ZNF276chr1689799710+0.0598416780.94015837
ENST00000263347ENST00000289816TCF25chr1689973730+ZNF276chr1689799710+0.0189417790.98105824
ENST00000263347ENST00000568064TCF25chr1689973730+ZNF276chr1689799710+0.043300570.9566995
ENST00000263347ENST00000443381TCF25chr1689973730+ZNF276chr1689799710+0.0426848940.95731515

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Fusion Genomic Features for TCF25-ZNF276


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TCF25chr1689973730+ZNF276chr1689799709+0.035898350.9641017
TCF25chr1689973730+ZNF276chr1689799709+0.035898350.9641017

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for TCF25-ZNF276


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:89973730/chr16:89799710)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneZNF276chr16:89973730chr16:89799710ENST00000289816511434_458314540.0Zinc fingerC2H2-type 1
TgeneZNF276chr16:89973730chr16:89799710ENST00000289816511465_490314540.0Zinc fingerC2H2-type 2
TgeneZNF276chr16:89973730chr16:89799710ENST00000289816511496_518314540.0Zinc fingerC2H2-type 3
TgeneZNF276chr16:89973730chr16:89799710ENST00000289816511524_546314540.0Zinc fingerC2H2-type 4
TgeneZNF276chr16:89973730chr16:89799710ENST00000289816511554_577314540.0Zinc fingerC2H2-type 5
TgeneZNF276chr16:89973730chr16:89799710ENST00000443381511434_458389615.0Zinc fingerC2H2-type 1
TgeneZNF276chr16:89973730chr16:89799710ENST00000443381511465_490389615.0Zinc fingerC2H2-type 2
TgeneZNF276chr16:89973730chr16:89799710ENST00000443381511496_518389615.0Zinc fingerC2H2-type 3
TgeneZNF276chr16:89973730chr16:89799710ENST00000443381511524_546389615.0Zinc fingerC2H2-type 4
TgeneZNF276chr16:89973730chr16:89799710ENST00000443381511554_577389615.0Zinc fingerC2H2-type 5

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneZNF276chr16:89973730chr16:89799710ENST0000028981651177_163314540.0DomainZAD
TgeneZNF276chr16:89973730chr16:89799710ENST0000044338151177_163389615.0DomainZAD


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Fusion Gene Sequence for TCF25-ZNF276


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>89759_89759_1_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263346_ZNF276_chr16_89799710_ENST00000289816_length(transcript)=5188nt_BP=1855nt
CCGAGTTTTCTGCGCTTCCTTCTCCCTCTCTCCAGACGTCGTGGTCGTTCGGTCCTATGTCGCGCCGGGCCCTCCGGAGGCTGAGGGGGG
AACAGCGCGGCCAGGAGCCCCTCGGGCCCGGCGCCTTGCATTTCGATCTCCGTGATGACGATGACGCGGAAGAAGAAGGGCCCAAGCGGG
AGCTTGGTGTCCGGCGTCCCGGGGGCGCAGGGAAGGAGGGCGTCCGAGTCAACAACCGCTTCGAGCTGATAAACATTGACGATCTTGAGG
ATGACCCTGTGGTGAACGGGGAGAGGTCTGGCTGTGCGCTCACAGACGCTGTGGCACCAGGGAACAAAGGAAGGGGTCAGCGTGGAAACA
CAGAGAGCAAGACGGATGGAGATGACACCGAGACAGTGCCCTCAGAGCAGTCTCATGCAAGTGGCAAACTCCGGAAGAAGAAAAAAAAAC
AGAAAAACAAGAAAAGCAGCACGGGAGAAGCATCGGAAAACGGACTAGAAGATATCGATCGCATCCTAGAGAGGATTGAGGACAGCACTG
GGTTGAACCGTCCCGGCCCAGCTCCCCTGAGCTCCAGGAAGCACGTTCTCTACGTGGAGCACAGACACTTGAATCCAGACACAGAACTGA
AAAGGTATTTTGGTGCCCGGGCAATCCTGGGGGAGCAAAGGCCACGGCAGAGACAACGTGTGTACCCCAAGTGCACATGGCTGACCACCC
CTAAAAGCACCTGGCCCCGCTACAGCAAACCAGGTCTGTCCATGCGGCTGCTGGAATCAAAAAAAGGCCTCTCCTTCTTTGCGTTTGAGC
ACAGTGAGGAGTACCAGCAGGCTCAGCACAAGTTCCTGGTGGCCGTGGAGTCTATGGAGCCGAACAACATCGTGGTTCTGCTCCAGACGA
GCCCTTACCACGTTGACTCACTCCTGCAGCTCAGCGATGCCTGCCGCTTTCAAGAGGATCAGGAGATGGCTCGAGACCTCGTAGAGAGAG
CGCTGTACAGCATGGAATGTGCGTTCCACCCCCTGTTCAGTCTCACCAGTGGGGCCTGCCGGCTGGATTACCGCAGACCCGAGAACAGGA
GCTTCTACCTGGCCCTCTACAAGCAGATGAGCTTCCTGGAGAAGCGAGGCTGCCCGCGCACGGCGCTGGAGTACTGCAAGCTCATCCTGA
GTCTCGAGCCGGATGAGGACCCCCTCTGCATGCTGCTGCTCATCGACCACCTGGCCTTGCGGGCCCGGAACTACGAGTACCTGATCCGCC
TCTTCCAGGAGTGGGAGGCTCATCGGAACCTGTCCCAGCTCCCTAATTTTGCCTTCTCTGTTCCACTGGCGTATTTCCTGCTGAGCCAGC
AGACAGACCTCCCTGAGTGTGAGCAGAGCTCTGCCAGGCAGAAGGCCTCTCTCCTGATACAGCAGGCGCTCACCATGTTCCCTGGAGTCC
TCCTGCCCCTGCTCGAGTCTTGCAGTGTGCGGCCCGACGCCAGCGTTTCCAGTCACCGCTTCTTTGGACCCAATGCTGAAATAAGCCAGC
CCCCTGCCCTGAGCCAGCTGGTGAACCTGTACCTTGGGAGGTCACACTTTCTCTGGAAAGAGCCCGCCACCATGAGCTGGCTGGAGGAGA
ACGTCCACGAGGTTCTGCAAGCAGTGGACGCCGGGGACCCAGCCGTGGAAGCCTGTGAGAACCGGCGGAAGGTGCTCTACCAGCGTGCAC
CCAGGAATATCCACCGCCATGTGATCCTCTCTGAGATCAAGGAAGCCGTCGCTGCCCTGCCCCCGGACGTGACCACGCAGTCTGTGATGG
GGTTTGATCCTCTGCCTCCTTCGGACACAATCTACTCCTACGTCAGGCCAGAGAGAGTCTCTGGTAAGAAGAGTGAAAGCAAAGAAGCCA
AGAAGTCTGAAGAACCAAGAATTCGGAAGAAGCCGGGACCCAAGCCCGGATGGAAGAAGAAGCTTCGTTGTGAGAGGGAGGAGCTTCCCA
CCATCTACAAGTGTCCTTACCAGGGCTGCACGGCCGTGTACCGAGGCGCTGACGGCATGAAGAAGCACATCAAGGAGCACCACGAGGAGG
TCCGGGAGCGGCCCTGCCCCCACCCTGGCTGCAACAAGGTTTTCATGATCGACCGCTACCTGCAGCGCCACGTGAAGCTCATCCACACAG
AGGTGCGGAACTATATCTGTGACGAATGTGGACAAACCTTCAAGCAGCGGAAGCACCTTCTCGTCCACCAAATGCGACATTCGGGAGCCA
AGCCTTTGCAGTGTGAGGTCTGTGGGTTCCAGTGCAGGCAGCGGGCATCCCTCAAGTACCACATGACCAAACACAAGGCTGAGACTGAGC
TGGACTTTGCCTGTGACCAGTGTGGCCGGCGGTTTGAGAAGGCCCACAACCTCAATGTACACATGTCCATGGTGCACCCGCTGACACAGA
CCCAGGACAAGGCCCTGCCCCTGGAGGCGGAACCACCACCTGGGCCACCGAGCCCCTCTGTGACCACAGAGGGCCAGGCGGTGAAGCCCG
AACCCACCTGAGGACGGCAGTGAGGATGAGCACCTCTAGCAGCCTGGACTCCGCAGTGGCTGTGTCAGCCTCACCCTTCGTGTGCACCCG
CATGGGAGGGTCGGAGGGTGCTGCCCGCCCTTGGTGCTGGAGGCGGGCTTGGTGTCCGGCTCAAGTAGCCTTCCTCTGCTCTGGGACCAG
TGGTTTATTTTCCCGCAAACGCTGAGTGACTCGGGGCCGGACAGTTCATAAATAATTGATTCCTTTCCCCACTAAAGCAGTCGAGGAGAT
TTGTAATCCACTTTTTAGTGCAACAAGAGCTCCATGTTATGCTTGTAATAAATTATTTACACGGGAGCTGGGCTGGTGTGCAGTGGCAGG
TCCCGTCAGAAGAGATGAGGCTCCTGGGACAGGTCAGCGTCAGGGGCAGCCTGCTGTCTGCTCTGGAGGGCGGCGCTCACCTCTGGGTCG
CAGTCCCCACGATCAGCCAGCAGCTGTGAGAGAGGAGCAGGTCCTCAGCCCATGCCGCCCACTAGGCCTCAGACCACAGGGGAGGGGCTC
TGGCAGAAATAGTCGAGTTGTATTGCCAGCCAGGCAGGCACATGGCCCAGGCAGCTGTCAATTCTCATGTCCCCCACATGGCCCAAGGTG
GGCATCTTGACGTTACCTCTGCCACGTGTGAGAAGCTCTTTTTCGGGCACCGAGGTATTAACTGCAGCAGAAAAAGACGAGCTTTTGTTA
TCAGTTCCACGGGGTTGCCCTAGAGAGAAAACAGGCAAACTCACAGGTTAGAAGACATACAGAAACAGGGCTGGTGTGTCCCCCATAGTC
TGCATGCTGTGCCGGAACATTCTTTGGCAGAAGGAGCCTCCGGCTGGGGGGAGCTCCCCTGGAGGTGGGACTGGCCCTTGCACCTGCCTG
ACCCTTGAGCTCCAGGCTCCTGCCAGCTGGAGGTGAAACTGTGCTTGTATCCCCAGCCACGAAGAGCTGGACCAGCTTCAAGTACATGTC
CACAGCAACATGCAGGAAGGCCTCTTCCCTGATGGCCGCGTCTTCATGGAAGTAGGAGAGAAGACTAGAGGTAAAGACATAGTGACAAAT
GGCTACAGACTGCTGGAAAGGTAGCAGGTGATGCCAAGGGATACTGCTCATCTGTGGAGCAGAGGCACAGACAACCCTTCCCATCTGGCG
GGACCCAGAGGTGCTGAGATGGGGGTCTGGGAAACACTGCCCAGCCCTGACCAGCCCTGTGGGTGGAGGTACCTGTAAAAAGCGAAAGGC
AGCAGCCTGGTGTGCTGATCCGGGGCCACACGGAGGAGGAGCCGCCCCAGCCTGAGGTCTGCAACACCAAGAAGTGGCTCAGGCAACTCT
GGACATCTCTGCCTATTATCAGTGCTGGGGACACCCCTGGGGGTCGGGACGTGTACCCTGGGAGGCCTGGCTGTGGGGATAGTGTGGGGC
GAACAGCCTGAGCTGAGGATACCCAGGTACCTGTCAGCAGCTGGGAGAGGATGGGGGGGTCGACCTCTTGCAGGAGGGTGGGTGTGGTGC
AGAGAGAGGCAGTCCCCATGATAGGCCCATTGGTCCTGGGGTTGACCAGTGAGCCAGTAAATTATCTTATTGCTTTAAACAAGTTTGTGC
TTAATCTGTCCCAACTAAAATGGAGCTTATAAACTTACTTAGCAAGGAACCTCAAGGAGGGCTCGTTCTTAACCATTTGCAAGATGCCTC
TGAAAAGAGCGGCCCTCCGCATTTGTGCCTCAGCAGCGTGTTTCTTACCACTCTCTGTCAACTGAAAGAGTGCCAGCCAGGATATCTTCC
TCTTCTCTAAACACTCGAGGATTGCTGCACAAACGTGGAAAGCCTTTGGCAGGTCTGTGGTGCTCTGTAAACCGCAGGAGACCAACCCTG
AGAATGGCCGACCTGGTGCTCCCATGGGTAGGAGGGTACAGCCCTCAGCACAGAAGAGGGCATTTCCTCTTTGCTTATTGTAAGTCTTAA
AACTGGTGACAGTTTTACCTATAGAAGGTAATACTGGGCCTCTGGACAGAAGAGGCTCAGGTAGGAGGCCAGGGACTTCGAGCACCCACA
CCAAGGCTGCTGCACCACGTCCTCAAATAAGACATTAAAAGAAAGGCCCACAGGCCGGATGCAGTGGCTCATGCCTGTAATCCCAACACT
TTGGGAGGCCGAGGTCGGCGGATCACTGAGGCCAGTTCAAGACCAGCCTGGCAATATGGTGAAACCCCGTCTCTACTAAAAATACAAAAA
TTAGCCGGGTGTGACAGACTCACGCCTGTAATCCCAGCTACTCGGGAGGCTGATGCAGGAGAATTGCTTGAACCCAGGAGGCTGAGGTTG
CAGTGAGCTGAGATCACACCACTGCACTCCAGCCTGGGTGACAGAGTGAGACCCCCATCTCAAAAAAAAAAAAAAAAAACCCACGGCCTG
GGAGTTCTCACTCACACTTCCGCAAACACAAGGAGCTCCTGAGCTAGTCTGGAAACCCTGACTTGGAAGCTGGCTGCCTGGTGCCCCTGC
CTGGCCCACAGTGGGAGAGGACACCTTGGCTGGTAAGGTCTGACTTACATTTGAGGTCAGATGTGACGACAGCAGGCCCATCAAGGAGAA

>89759_89759_1_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263346_ZNF276_chr16_89799710_ENST00000289816_length(amino acids)=824AA_BP=599
MSRRALRRLRGEQRGQEPLGPGALHFDLRDDDDAEEEGPKRELGVRRPGGAGKEGVRVNNRFELINIDDLEDDPVVNGERSGCALTDAVA
PGNKGRGQRGNTESKTDGDDTETVPSEQSHASGKLRKKKKKQKNKKSSTGEASENGLEDIDRILERIEDSTGLNRPGPAPLSSRKHVLYV
EHRHLNPDTELKRYFGARAILGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEHSEEYQQAQHKFLVAVESM
EPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLVERALYSMECAFHPLFSLTSGACRLDYRRPENRSFYLALYKQMSFLEKRGCP
RTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPECEQSSARQKASLL
IQQALTMFPGVLLPLLESCSVRPDASVSSHRFFGPNAEISQPPALSQLVNLYLGRSHFLWKEPATMSWLEENVHEVLQAVDAGDPAVEAC
ENRRKVLYQRAPRNIHRHVILSEIKEAVAALPPDVTTQSVMGFDPLPPSDTIYSYVRPERVSGKKSESKEAKKSEEPRIRKKPGPKPGWK
KKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKH
LLVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQTQDKALPLEAEPPPGPPSP

--------------------------------------------------------------
>89759_89759_2_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263346_ZNF276_chr16_89799710_ENST00000443381_length(transcript)=2856nt_BP=1855nt
CCGAGTTTTCTGCGCTTCCTTCTCCCTCTCTCCAGACGTCGTGGTCGTTCGGTCCTATGTCGCGCCGGGCCCTCCGGAGGCTGAGGGGGG
AACAGCGCGGCCAGGAGCCCCTCGGGCCCGGCGCCTTGCATTTCGATCTCCGTGATGACGATGACGCGGAAGAAGAAGGGCCCAAGCGGG
AGCTTGGTGTCCGGCGTCCCGGGGGCGCAGGGAAGGAGGGCGTCCGAGTCAACAACCGCTTCGAGCTGATAAACATTGACGATCTTGAGG
ATGACCCTGTGGTGAACGGGGAGAGGTCTGGCTGTGCGCTCACAGACGCTGTGGCACCAGGGAACAAAGGAAGGGGTCAGCGTGGAAACA
CAGAGAGCAAGACGGATGGAGATGACACCGAGACAGTGCCCTCAGAGCAGTCTCATGCAAGTGGCAAACTCCGGAAGAAGAAAAAAAAAC
AGAAAAACAAGAAAAGCAGCACGGGAGAAGCATCGGAAAACGGACTAGAAGATATCGATCGCATCCTAGAGAGGATTGAGGACAGCACTG
GGTTGAACCGTCCCGGCCCAGCTCCCCTGAGCTCCAGGAAGCACGTTCTCTACGTGGAGCACAGACACTTGAATCCAGACACAGAACTGA
AAAGGTATTTTGGTGCCCGGGCAATCCTGGGGGAGCAAAGGCCACGGCAGAGACAACGTGTGTACCCCAAGTGCACATGGCTGACCACCC
CTAAAAGCACCTGGCCCCGCTACAGCAAACCAGGTCTGTCCATGCGGCTGCTGGAATCAAAAAAAGGCCTCTCCTTCTTTGCGTTTGAGC
ACAGTGAGGAGTACCAGCAGGCTCAGCACAAGTTCCTGGTGGCCGTGGAGTCTATGGAGCCGAACAACATCGTGGTTCTGCTCCAGACGA
GCCCTTACCACGTTGACTCACTCCTGCAGCTCAGCGATGCCTGCCGCTTTCAAGAGGATCAGGAGATGGCTCGAGACCTCGTAGAGAGAG
CGCTGTACAGCATGGAATGTGCGTTCCACCCCCTGTTCAGTCTCACCAGTGGGGCCTGCCGGCTGGATTACCGCAGACCCGAGAACAGGA
GCTTCTACCTGGCCCTCTACAAGCAGATGAGCTTCCTGGAGAAGCGAGGCTGCCCGCGCACGGCGCTGGAGTACTGCAAGCTCATCCTGA
GTCTCGAGCCGGATGAGGACCCCCTCTGCATGCTGCTGCTCATCGACCACCTGGCCTTGCGGGCCCGGAACTACGAGTACCTGATCCGCC
TCTTCCAGGAGTGGGAGGCTCATCGGAACCTGTCCCAGCTCCCTAATTTTGCCTTCTCTGTTCCACTGGCGTATTTCCTGCTGAGCCAGC
AGACAGACCTCCCTGAGTGTGAGCAGAGCTCTGCCAGGCAGAAGGCCTCTCTCCTGATACAGCAGGCGCTCACCATGTTCCCTGGAGTCC
TCCTGCCCCTGCTCGAGTCTTGCAGTGTGCGGCCCGACGCCAGCGTTTCCAGTCACCGCTTCTTTGGACCCAATGCTGAAATAAGCCAGC
CCCCTGCCCTGAGCCAGCTGGTGAACCTGTACCTTGGGAGGTCACACTTTCTCTGGAAAGAGCCCGCCACCATGAGCTGGCTGGAGGAGA
ACGTCCACGAGGTTCTGCAAGCAGTGGACGCCGGGGACCCAGCCGTGGAAGCCTGTGAGAACCGGCGGAAGGTGCTCTACCAGCGTGCAC
CCAGGAATATCCACCGCCATGTGATCCTCTCTGAGATCAAGGAAGCCGTCGCTGCCCTGCCCCCGGACGTGACCACGCAGTCTGTGATGG
GGTTTGATCCTCTGCCTCCTTCGGACACAATCTACTCCTACGTCAGGCCAGAGAGAGTCTCTGGTAAGAAGAGTGAAAGCAAAGAAGCCA
AGAAGTCTGAAGAACCAAGAATTCGGAAGAAGCCGGGACCCAAGCCCGGATGGAAGAAGAAGCTTCGTTGTGAGAGGGAGGAGCTTCCCA
CCATCTACAAGTGTCCTTACCAGGGCTGCACGGCCGTGTACCGAGGCGCTGACGGCATGAAGAAGCACATCAAGGAGCACCACGAGGAGG
TCCGGGAGCGGCCCTGCCCCCACCCTGGCTGCAACAAGGTTTTCATGATCGACCGCTACCTGCAGCGCCACGTGAAGCTCATCCACACAG
AGGTGCGGAACTATATCTGTGACGAATGTGGACAAACCTTCAAGCAGCGGAAGCACCTTCTCGTCCACCAAATGCGACATTCGGGAGCCA
AGCCTTTGCAGTGTGAGGTCTGTGGGTTCCAGTGCAGGCAGCGGGCATCCCTCAAGTACCACATGACCAAACACAAGGCTGAGACTGAGC
TGGACTTTGCCTGTGACCAGTGTGGCCGGCGGTTTGAGAAGGCCCACAACCTCAATGTACACATGTCCATGGTGCACCCGCTGACACAGA
CCCAGGACAAGGCCCTGCCCCTGGAGGCGGAACCACCACCTGGGCCACCGAGCCCCTCTGTGACCACAGAGGGCCAGGCGGTGAAGCCCG
AACCCACCTGAGGACGGCAGTGAGGATGAGCACCTCTAGCAGCCTGGACTCCGCAGTGGCTGTGTCAGCCTCACCCTTCGTGTGCACCCG
CATGGGAGGGTCGGAGGGTGCTGCCCGCCCTTGGTGCTGGAGGCGGGCTTGGTGTCCGGCTCAAGTAGCCTTCCTCTGCTCTGGGACCAG
TGGTTTATTTTCCCGCAAACGCTGAGTGACTCGGGGCCGGACAGTTCATAAATAATTGATTCCTTTCCCCACTAAAGCAGTCGAGGAGAT

>89759_89759_2_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263346_ZNF276_chr16_89799710_ENST00000443381_length(amino acids)=824AA_BP=599
MSRRALRRLRGEQRGQEPLGPGALHFDLRDDDDAEEEGPKRELGVRRPGGAGKEGVRVNNRFELINIDDLEDDPVVNGERSGCALTDAVA
PGNKGRGQRGNTESKTDGDDTETVPSEQSHASGKLRKKKKKQKNKKSSTGEASENGLEDIDRILERIEDSTGLNRPGPAPLSSRKHVLYV
EHRHLNPDTELKRYFGARAILGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEHSEEYQQAQHKFLVAVESM
EPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLVERALYSMECAFHPLFSLTSGACRLDYRRPENRSFYLALYKQMSFLEKRGCP
RTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPECEQSSARQKASLL
IQQALTMFPGVLLPLLESCSVRPDASVSSHRFFGPNAEISQPPALSQLVNLYLGRSHFLWKEPATMSWLEENVHEVLQAVDAGDPAVEAC
ENRRKVLYQRAPRNIHRHVILSEIKEAVAALPPDVTTQSVMGFDPLPPSDTIYSYVRPERVSGKKSESKEAKKSEEPRIRKKPGPKPGWK
KKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKH
LLVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQTQDKALPLEAEPPPGPPSP

--------------------------------------------------------------
>89759_89759_3_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263346_ZNF276_chr16_89799710_ENST00000446326_length(transcript)=2566nt_BP=1855nt
CCGAGTTTTCTGCGCTTCCTTCTCCCTCTCTCCAGACGTCGTGGTCGTTCGGTCCTATGTCGCGCCGGGCCCTCCGGAGGCTGAGGGGGG
AACAGCGCGGCCAGGAGCCCCTCGGGCCCGGCGCCTTGCATTTCGATCTCCGTGATGACGATGACGCGGAAGAAGAAGGGCCCAAGCGGG
AGCTTGGTGTCCGGCGTCCCGGGGGCGCAGGGAAGGAGGGCGTCCGAGTCAACAACCGCTTCGAGCTGATAAACATTGACGATCTTGAGG
ATGACCCTGTGGTGAACGGGGAGAGGTCTGGCTGTGCGCTCACAGACGCTGTGGCACCAGGGAACAAAGGAAGGGGTCAGCGTGGAAACA
CAGAGAGCAAGACGGATGGAGATGACACCGAGACAGTGCCCTCAGAGCAGTCTCATGCAAGTGGCAAACTCCGGAAGAAGAAAAAAAAAC
AGAAAAACAAGAAAAGCAGCACGGGAGAAGCATCGGAAAACGGACTAGAAGATATCGATCGCATCCTAGAGAGGATTGAGGACAGCACTG
GGTTGAACCGTCCCGGCCCAGCTCCCCTGAGCTCCAGGAAGCACGTTCTCTACGTGGAGCACAGACACTTGAATCCAGACACAGAACTGA
AAAGGTATTTTGGTGCCCGGGCAATCCTGGGGGAGCAAAGGCCACGGCAGAGACAACGTGTGTACCCCAAGTGCACATGGCTGACCACCC
CTAAAAGCACCTGGCCCCGCTACAGCAAACCAGGTCTGTCCATGCGGCTGCTGGAATCAAAAAAAGGCCTCTCCTTCTTTGCGTTTGAGC
ACAGTGAGGAGTACCAGCAGGCTCAGCACAAGTTCCTGGTGGCCGTGGAGTCTATGGAGCCGAACAACATCGTGGTTCTGCTCCAGACGA
GCCCTTACCACGTTGACTCACTCCTGCAGCTCAGCGATGCCTGCCGCTTTCAAGAGGATCAGGAGATGGCTCGAGACCTCGTAGAGAGAG
CGCTGTACAGCATGGAATGTGCGTTCCACCCCCTGTTCAGTCTCACCAGTGGGGCCTGCCGGCTGGATTACCGCAGACCCGAGAACAGGA
GCTTCTACCTGGCCCTCTACAAGCAGATGAGCTTCCTGGAGAAGCGAGGCTGCCCGCGCACGGCGCTGGAGTACTGCAAGCTCATCCTGA
GTCTCGAGCCGGATGAGGACCCCCTCTGCATGCTGCTGCTCATCGACCACCTGGCCTTGCGGGCCCGGAACTACGAGTACCTGATCCGCC
TCTTCCAGGAGTGGGAGGCTCATCGGAACCTGTCCCAGCTCCCTAATTTTGCCTTCTCTGTTCCACTGGCGTATTTCCTGCTGAGCCAGC
AGACAGACCTCCCTGAGTGTGAGCAGAGCTCTGCCAGGCAGAAGGCCTCTCTCCTGATACAGCAGGCGCTCACCATGTTCCCTGGAGTCC
TCCTGCCCCTGCTCGAGTCTTGCAGTGTGCGGCCCGACGCCAGCGTTTCCAGTCACCGCTTCTTTGGACCCAATGCTGAAATAAGCCAGC
CCCCTGCCCTGAGCCAGCTGGTGAACCTGTACCTTGGGAGGTCACACTTTCTCTGGAAAGAGCCCGCCACCATGAGCTGGCTGGAGGAGA
ACGTCCACGAGGTTCTGCAAGCAGTGGACGCCGGGGACCCAGCCGTGGAAGCCTGTGAGAACCGGCGGAAGGTGCTCTACCAGCGTGCAC
CCAGGAATATCCACCGCCATGTGATCCTCTCTGAGATCAAGGAAGCCGTCGCTGCCCTGCCCCCGGACGTGACCACGCAGTCTGTGATGG
GGTTTGATCCTCTGCCTCCTTCGGACACAATCTACTCCTACGTCAGGCCAGAGAGAGTCTCTGGTAAGAAGAGTGAAAGCAAAGAAGCCA
AGAAGTCTGAAGAACCAAGAATTCGGAAGAAGCCGGGACCCAAGCCCGGATGGAAGAAGAAGCTTCGTTGTGAGAGGGAGGAGCTTCCCA
CCATCTACAAGTGTCCTTACCAGGGCTGCACGGCCGTGTACCGAGGCGCTGACGGCATGAAGAAGCACATCAAGGAGCACCACGAGGAGG
TCCGGGAGCGGCCCTGCCCCCACCCTGGCTGCAACAAGGTTTTCATGATCGACCGCTACCTGCAGCGCCACGTGAAGCTCATCCACACAG
AGGTGCGGAACTATATCTGTGACGAATGTGGACAAACCTTCAAGCAGCGGAAGCACCTTCTCGTCCACCAAATGCGACATTCGGGAGCCA
AGCCTTTGCAGTGTGAGGTCTGTGGGTTCCAGTGCAGGCAGCGGGCATCCCTCAAGTACCACATGACCAAACACAAGGCTGAGACTGAGC
TGGACTTTGCCTGTGACCAGTGTGGCCGGCGGTTTGAGAAGGCCCACAACCTCAATGTACACATGTCCATGGTGCACCCGCTGACACAGA
CCCAGGACAAGGCCCTGCCCCTGGAGGCGGAACCACCACCTGGGCCACCGAGCCCCTCTGTGACCACAGAGGGCCAGGCGGTGAAGCCCG

>89759_89759_3_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263346_ZNF276_chr16_89799710_ENST00000446326_length(amino acids)=824AA_BP=599
MSRRALRRLRGEQRGQEPLGPGALHFDLRDDDDAEEEGPKRELGVRRPGGAGKEGVRVNNRFELINIDDLEDDPVVNGERSGCALTDAVA
PGNKGRGQRGNTESKTDGDDTETVPSEQSHASGKLRKKKKKQKNKKSSTGEASENGLEDIDRILERIEDSTGLNRPGPAPLSSRKHVLYV
EHRHLNPDTELKRYFGARAILGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEHSEEYQQAQHKFLVAVESM
EPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLVERALYSMECAFHPLFSLTSGACRLDYRRPENRSFYLALYKQMSFLEKRGCP
RTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPECEQSSARQKASLL
IQQALTMFPGVLLPLLESCSVRPDASVSSHRFFGPNAEISQPPALSQLVNLYLGRSHFLWKEPATMSWLEENVHEVLQAVDAGDPAVEAC
ENRRKVLYQRAPRNIHRHVILSEIKEAVAALPPDVTTQSVMGFDPLPPSDTIYSYVRPERVSGKKSESKEAKKSEEPRIRKKPGPKPGWK
KKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKH
LLVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQTQDKALPLEAEPPPGPPSP

--------------------------------------------------------------
>89759_89759_4_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263346_ZNF276_chr16_89799710_ENST00000568064_length(transcript)=2875nt_BP=1855nt
CCGAGTTTTCTGCGCTTCCTTCTCCCTCTCTCCAGACGTCGTGGTCGTTCGGTCCTATGTCGCGCCGGGCCCTCCGGAGGCTGAGGGGGG
AACAGCGCGGCCAGGAGCCCCTCGGGCCCGGCGCCTTGCATTTCGATCTCCGTGATGACGATGACGCGGAAGAAGAAGGGCCCAAGCGGG
AGCTTGGTGTCCGGCGTCCCGGGGGCGCAGGGAAGGAGGGCGTCCGAGTCAACAACCGCTTCGAGCTGATAAACATTGACGATCTTGAGG
ATGACCCTGTGGTGAACGGGGAGAGGTCTGGCTGTGCGCTCACAGACGCTGTGGCACCAGGGAACAAAGGAAGGGGTCAGCGTGGAAACA
CAGAGAGCAAGACGGATGGAGATGACACCGAGACAGTGCCCTCAGAGCAGTCTCATGCAAGTGGCAAACTCCGGAAGAAGAAAAAAAAAC
AGAAAAACAAGAAAAGCAGCACGGGAGAAGCATCGGAAAACGGACTAGAAGATATCGATCGCATCCTAGAGAGGATTGAGGACAGCACTG
GGTTGAACCGTCCCGGCCCAGCTCCCCTGAGCTCCAGGAAGCACGTTCTCTACGTGGAGCACAGACACTTGAATCCAGACACAGAACTGA
AAAGGTATTTTGGTGCCCGGGCAATCCTGGGGGAGCAAAGGCCACGGCAGAGACAACGTGTGTACCCCAAGTGCACATGGCTGACCACCC
CTAAAAGCACCTGGCCCCGCTACAGCAAACCAGGTCTGTCCATGCGGCTGCTGGAATCAAAAAAAGGCCTCTCCTTCTTTGCGTTTGAGC
ACAGTGAGGAGTACCAGCAGGCTCAGCACAAGTTCCTGGTGGCCGTGGAGTCTATGGAGCCGAACAACATCGTGGTTCTGCTCCAGACGA
GCCCTTACCACGTTGACTCACTCCTGCAGCTCAGCGATGCCTGCCGCTTTCAAGAGGATCAGGAGATGGCTCGAGACCTCGTAGAGAGAG
CGCTGTACAGCATGGAATGTGCGTTCCACCCCCTGTTCAGTCTCACCAGTGGGGCCTGCCGGCTGGATTACCGCAGACCCGAGAACAGGA
GCTTCTACCTGGCCCTCTACAAGCAGATGAGCTTCCTGGAGAAGCGAGGCTGCCCGCGCACGGCGCTGGAGTACTGCAAGCTCATCCTGA
GTCTCGAGCCGGATGAGGACCCCCTCTGCATGCTGCTGCTCATCGACCACCTGGCCTTGCGGGCCCGGAACTACGAGTACCTGATCCGCC
TCTTCCAGGAGTGGGAGGCTCATCGGAACCTGTCCCAGCTCCCTAATTTTGCCTTCTCTGTTCCACTGGCGTATTTCCTGCTGAGCCAGC
AGACAGACCTCCCTGAGTGTGAGCAGAGCTCTGCCAGGCAGAAGGCCTCTCTCCTGATACAGCAGGCGCTCACCATGTTCCCTGGAGTCC
TCCTGCCCCTGCTCGAGTCTTGCAGTGTGCGGCCCGACGCCAGCGTTTCCAGTCACCGCTTCTTTGGACCCAATGCTGAAATAAGCCAGC
CCCCTGCCCTGAGCCAGCTGGTGAACCTGTACCTTGGGAGGTCACACTTTCTCTGGAAAGAGCCCGCCACCATGAGCTGGCTGGAGGAGA
ACGTCCACGAGGTTCTGCAAGCAGTGGACGCCGGGGACCCAGCCGTGGAAGCCTGTGAGAACCGGCGGAAGGTGCTCTACCAGCGTGCAC
CCAGGAATATCCACCGCCATGTGATCCTCTCTGAGATCAAGGAAGCCGTCGCTGCCCTGCCCCCGGACGTGACCACGCAGTCTGTGATGG
GGTTTGATCCTCTGCCTCCTTCGGACACAATCTACTCCTACGTCAGGCCAGAGAGAGTCTCTGGTAAGAAGAGTGAAAGCAAAGAAGCCA
AGAAGTCTGAAGAACCAAGAATTCGGAAGAAGCCGGGACCCAAGCCCGGATGGAAGAAGAAGCTTCGTTGTGAGAGGGAGGAGCTTCCCA
CCATCTACAAGTGTCCTTACCAGGGCTGCACGGCCGTGTACCGAGGCGCTGACGGCATGAAGAAGCACATCAAGGAGCACCACGAGGAGG
TCCGGGAGCGGCCCTGCCCCCACCCTGGCTGCAACAAGGTTTTCATGATCGACCGCTACCTGCAGCGCCACGTGAAGCTCATCCACACAG
AGGTGCGGAACTATATCTGTGACGAATGTGGACAAACCTTCAAGCAGCGGAAGCACCTTCTCGTCCACCAAATGCGACATTCGGGAGCCA
AGCCTTTGCAGTAAGTGTGAGTCAGGACCCCCTCCCAGGGCTGTGGCCCTCGCACCTTCTTATCTGCCTCTGTCCCCCAGGTGTGAGGTC
TGTGGGTTCCAGTGCAGGCAGCGGGCATCCCTCAAGTACCACATGACCAAACACAAGGCTGAGACTGAGCTGGACTTTGCCTGTGACCAG
TGTGGCCGGCGGTTTGAGAAGGCCCACAACCTCAATGTACACATGTCCATGGTGCACCCGCTGACACAGACCCAGGACAAGGCCCTGCCC
CTGGAGGCGGAACCACCACCTGGGCCACCGAGCCCCTCTGTGACCACAGAGGGCCAGGCGGTGAAGCCCGAACCCACCTGAGGACGGCAG
TGAGGATGAGCACCTCTAGCAGCCTGGACTCCGCAGTGGCTGTGTCAGCCTCACCCTTCGTGTGCACCCGCATGGGAGGGTCGGAGGGTG
CTGCCCGCCCTTGGTGCTGGAGGCGGGCTTGGTGTCCGGCTCAAGTAGCCTTCCTCTGCTCTGGGACCAGTGGTTTATTTTCCCGCAAAC

>89759_89759_4_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263346_ZNF276_chr16_89799710_ENST00000568064_length(amino acids)=735AA_BP=599
MSRRALRRLRGEQRGQEPLGPGALHFDLRDDDDAEEEGPKRELGVRRPGGAGKEGVRVNNRFELINIDDLEDDPVVNGERSGCALTDAVA
PGNKGRGQRGNTESKTDGDDTETVPSEQSHASGKLRKKKKKQKNKKSSTGEASENGLEDIDRILERIEDSTGLNRPGPAPLSSRKHVLYV
EHRHLNPDTELKRYFGARAILGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEHSEEYQQAQHKFLVAVESM
EPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLVERALYSMECAFHPLFSLTSGACRLDYRRPENRSFYLALYKQMSFLEKRGCP
RTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPECEQSSARQKASLL
IQQALTMFPGVLLPLLESCSVRPDASVSSHRFFGPNAEISQPPALSQLVNLYLGRSHFLWKEPATMSWLEENVHEVLQAVDAGDPAVEAC
ENRRKVLYQRAPRNIHRHVILSEIKEAVAALPPDVTTQSVMGFDPLPPSDTIYSYVRPERVSGKKSESKEAKKSEEPRIRKKPGPKPGWK
KKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKH

--------------------------------------------------------------
>89759_89759_5_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263347_ZNF276_chr16_89799710_ENST00000289816_length(transcript)=4706nt_BP=1373nt
TAGGAAAACGGACTAGAAGATATCGATCGCATCCTAGAGAGGATTGAGGACAGCACTGGGTTGAACCGTCCCGGCCCAGCTCCCCTGAGC
TCCAGGAAGCACGTTCTCTACGTGGAGCACAGACACTTGAATCCAGACACAGAACTGAAAAGGTATTTTGGTGCCCGGGCAATCCTGGGG
GAGCAAAGGCCACGGCAGAGACAACGTGTGTACCCCAAGTGCACATGGCTGACCACCCCTAAAAGCACCTGGCCCCGCTACAGCAAACCA
GGTCTGTCCATGCGGCTGCTGGAATCAAAAAAAGGCCTCTCCTTCTTTGCGTTTGAGCACAGTGAGGAGTACCAGCAGGCTCAGCACAAG
TTCCTGGTGGCCGTGGAGTCTATGGAGCCGAACAACATCGTGGTTCTGCTCCAGACGAGCCCTTACCACGTTGACTCACTCCTGCAGCTC
AGCGATGCCTGCCGCTTTCAAGAGGATCAGGAGATGGCTCGAGACCTCGTAGAGAGAGCGCTGTACAGCATGGAATGTGCGTTCCACCCC
CTGTTCAGTCTCACCAGTGGGGCCTGCCGGCTGGATTACCGCAGACCCGAGAACAGGAGCTTCTACCTGGCCCTCTACAAGCAGATGAGC
TTCCTGGAGAAGCGAGGCTGCCCGCGCACGGCGCTGGAGTACTGCAAGCTCATCCTGAGTCTCGAGCCGGATGAGGACCCCCTCTGCATG
CTGCTGCTCATCGACCACCTGGCCTTGCGGGCCCGGAACTACGAGTACCTGATCCGCCTCTTCCAGGAGTGGGAGGCTCATCGGAACCTG
TCCCAGCTCCCTAATTTTGCCTTCTCTGTTCCACTGGCGTATTTCCTGCTGAGCCAGCAGACAGACCTCCCTGAGTGTGAGCAGAGCTCT
GCCAGGCAGAAGGCCTCTCTCCTGATACAGCAGGCGCTCACCATGTTCCCTGGAGTCCTCCTGCCCCTGCTCGAGTCTTGCAGTGTGCGG
CCCGACGCCAGCGTTTCCAGTCACCGCTTCTTTGGACCCAATGCTGAAATAAGCCAGCCCCCTGCCCTGAGCCAGCTGGTGAACCTGTAC
CTTGGGAGGTCACACTTTCTCTGGAAAGAGCCCGCCACCATGAGCTGGCTGGAGGAGAACGTCCACGAGGTTCTGCAAGCAGTGGACGCC
GGGGACCCAGCCGTGGAAGCCTGTGAGAACCGGCGGAAGGTGCTCTACCAGCGTGCACCCAGGAATATCCACCGCCATGTGATCCTCTCT
GAGATCAAGGAAGCCGTCGCTGCCCTGCCCCCGGACGTGACCACGCAGTCTGTGATGGGGTTTGATCCTCTGCCTCCTTCGGACACAATC
TACTCCTACGTCAGGCCAGAGAGAGTCTCTGGTAAGAAGAGTGAAAGCAAAGAAGCCAAGAAGTCTGAAGAACCAAGAATTCGGAAGAAG
CCGGGACCCAAGCCCGGATGGAAGAAGAAGCTTCGTTGTGAGAGGGAGGAGCTTCCCACCATCTACAAGTGTCCTTACCAGGGCTGCACG
GCCGTGTACCGAGGCGCTGACGGCATGAAGAAGCACATCAAGGAGCACCACGAGGAGGTCCGGGAGCGGCCCTGCCCCCACCCTGGCTGC
AACAAGGTTTTCATGATCGACCGCTACCTGCAGCGCCACGTGAAGCTCATCCACACAGAGGTGCGGAACTATATCTGTGACGAATGTGGA
CAAACCTTCAAGCAGCGGAAGCACCTTCTCGTCCACCAAATGCGACATTCGGGAGCCAAGCCTTTGCAGTGTGAGGTCTGTGGGTTCCAG
TGCAGGCAGCGGGCATCCCTCAAGTACCACATGACCAAACACAAGGCTGAGACTGAGCTGGACTTTGCCTGTGACCAGTGTGGCCGGCGG
TTTGAGAAGGCCCACAACCTCAATGTACACATGTCCATGGTGCACCCGCTGACACAGACCCAGGACAAGGCCCTGCCCCTGGAGGCGGAA
CCACCACCTGGGCCACCGAGCCCCTCTGTGACCACAGAGGGCCAGGCGGTGAAGCCCGAACCCACCTGAGGACGGCAGTGAGGATGAGCA
CCTCTAGCAGCCTGGACTCCGCAGTGGCTGTGTCAGCCTCACCCTTCGTGTGCACCCGCATGGGAGGGTCGGAGGGTGCTGCCCGCCCTT
GGTGCTGGAGGCGGGCTTGGTGTCCGGCTCAAGTAGCCTTCCTCTGCTCTGGGACCAGTGGTTTATTTTCCCGCAAACGCTGAGTGACTC
GGGGCCGGACAGTTCATAAATAATTGATTCCTTTCCCCACTAAAGCAGTCGAGGAGATTTGTAATCCACTTTTTAGTGCAACAAGAGCTC
CATGTTATGCTTGTAATAAATTATTTACACGGGAGCTGGGCTGGTGTGCAGTGGCAGGTCCCGTCAGAAGAGATGAGGCTCCTGGGACAG
GTCAGCGTCAGGGGCAGCCTGCTGTCTGCTCTGGAGGGCGGCGCTCACCTCTGGGTCGCAGTCCCCACGATCAGCCAGCAGCTGTGAGAG
AGGAGCAGGTCCTCAGCCCATGCCGCCCACTAGGCCTCAGACCACAGGGGAGGGGCTCTGGCAGAAATAGTCGAGTTGTATTGCCAGCCA
GGCAGGCACATGGCCCAGGCAGCTGTCAATTCTCATGTCCCCCACATGGCCCAAGGTGGGCATCTTGACGTTACCTCTGCCACGTGTGAG
AAGCTCTTTTTCGGGCACCGAGGTATTAACTGCAGCAGAAAAAGACGAGCTTTTGTTATCAGTTCCACGGGGTTGCCCTAGAGAGAAAAC
AGGCAAACTCACAGGTTAGAAGACATACAGAAACAGGGCTGGTGTGTCCCCCATAGTCTGCATGCTGTGCCGGAACATTCTTTGGCAGAA
GGAGCCTCCGGCTGGGGGGAGCTCCCCTGGAGGTGGGACTGGCCCTTGCACCTGCCTGACCCTTGAGCTCCAGGCTCCTGCCAGCTGGAG
GTGAAACTGTGCTTGTATCCCCAGCCACGAAGAGCTGGACCAGCTTCAAGTACATGTCCACAGCAACATGCAGGAAGGCCTCTTCCCTGA
TGGCCGCGTCTTCATGGAAGTAGGAGAGAAGACTAGAGGTAAAGACATAGTGACAAATGGCTACAGACTGCTGGAAAGGTAGCAGGTGAT
GCCAAGGGATACTGCTCATCTGTGGAGCAGAGGCACAGACAACCCTTCCCATCTGGCGGGACCCAGAGGTGCTGAGATGGGGGTCTGGGA
AACACTGCCCAGCCCTGACCAGCCCTGTGGGTGGAGGTACCTGTAAAAAGCGAAAGGCAGCAGCCTGGTGTGCTGATCCGGGGCCACACG
GAGGAGGAGCCGCCCCAGCCTGAGGTCTGCAACACCAAGAAGTGGCTCAGGCAACTCTGGACATCTCTGCCTATTATCAGTGCTGGGGAC
ACCCCTGGGGGTCGGGACGTGTACCCTGGGAGGCCTGGCTGTGGGGATAGTGTGGGGCGAACAGCCTGAGCTGAGGATACCCAGGTACCT
GTCAGCAGCTGGGAGAGGATGGGGGGGTCGACCTCTTGCAGGAGGGTGGGTGTGGTGCAGAGAGAGGCAGTCCCCATGATAGGCCCATTG
GTCCTGGGGTTGACCAGTGAGCCAGTAAATTATCTTATTGCTTTAAACAAGTTTGTGCTTAATCTGTCCCAACTAAAATGGAGCTTATAA
ACTTACTTAGCAAGGAACCTCAAGGAGGGCTCGTTCTTAACCATTTGCAAGATGCCTCTGAAAAGAGCGGCCCTCCGCATTTGTGCCTCA
GCAGCGTGTTTCTTACCACTCTCTGTCAACTGAAAGAGTGCCAGCCAGGATATCTTCCTCTTCTCTAAACACTCGAGGATTGCTGCACAA
ACGTGGAAAGCCTTTGGCAGGTCTGTGGTGCTCTGTAAACCGCAGGAGACCAACCCTGAGAATGGCCGACCTGGTGCTCCCATGGGTAGG
AGGGTACAGCCCTCAGCACAGAAGAGGGCATTTCCTCTTTGCTTATTGTAAGTCTTAAAACTGGTGACAGTTTTACCTATAGAAGGTAAT
ACTGGGCCTCTGGACAGAAGAGGCTCAGGTAGGAGGCCAGGGACTTCGAGCACCCACACCAAGGCTGCTGCACCACGTCCTCAAATAAGA
CATTAAAAGAAAGGCCCACAGGCCGGATGCAGTGGCTCATGCCTGTAATCCCAACACTTTGGGAGGCCGAGGTCGGCGGATCACTGAGGC
CAGTTCAAGACCAGCCTGGCAATATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCGGGTGTGACAGACTCACGCCTGTAAT
CCCAGCTACTCGGGAGGCTGATGCAGGAGAATTGCTTGAACCCAGGAGGCTGAGGTTGCAGTGAGCTGAGATCACACCACTGCACTCCAG
CCTGGGTGACAGAGTGAGACCCCCATCTCAAAAAAAAAAAAAAAAAACCCACGGCCTGGGAGTTCTCACTCACACTTCCGCAAACACAAG
GAGCTCCTGAGCTAGTCTGGAAACCCTGACTTGGAAGCTGGCTGCCTGGTGCCCCTGCCTGGCCCACAGTGGGAGAGGACACCTTGGCTG
GTAAGGTCTGACTTACATTTGAGGTCAGATGTGACGACAGCAGGCCCATCAAGGAGAAGAAGAAAAGGAAAACCAATAGCTGTAAATAAA

>89759_89759_5_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263347_ZNF276_chr16_89799710_ENST00000289816_length(amino acids)=662AA_BP=437
MNRPGPAPLSSRKHVLYVEHRHLNPDTELKRYFGARAILGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEH
SEEYQQAQHKFLVAVESMEPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLVERALYSMECAFHPLFSLTSGACRLDYRRPENRS
FYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQ
TDLPECEQSSARQKASLLIQQALTMFPGVLLPLLESCSVRPDASVSSHRFFGPNAEISQPPALSQLVNLYLGRSHFLWKEPATMSWLEEN
VHEVLQAVDAGDPAVEACENRRKVLYQRAPRNIHRHVILSEIKEAVAALPPDVTTQSVMGFDPLPPSDTIYSYVRPERVSGKKSESKEAK
KSEEPRIRKKPGPKPGWKKKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTE
VRNYICDECGQTFKQRKHLLVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQT

--------------------------------------------------------------
>89759_89759_6_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263347_ZNF276_chr16_89799710_ENST00000443381_length(transcript)=2374nt_BP=1373nt
TAGGAAAACGGACTAGAAGATATCGATCGCATCCTAGAGAGGATTGAGGACAGCACTGGGTTGAACCGTCCCGGCCCAGCTCCCCTGAGC
TCCAGGAAGCACGTTCTCTACGTGGAGCACAGACACTTGAATCCAGACACAGAACTGAAAAGGTATTTTGGTGCCCGGGCAATCCTGGGG
GAGCAAAGGCCACGGCAGAGACAACGTGTGTACCCCAAGTGCACATGGCTGACCACCCCTAAAAGCACCTGGCCCCGCTACAGCAAACCA
GGTCTGTCCATGCGGCTGCTGGAATCAAAAAAAGGCCTCTCCTTCTTTGCGTTTGAGCACAGTGAGGAGTACCAGCAGGCTCAGCACAAG
TTCCTGGTGGCCGTGGAGTCTATGGAGCCGAACAACATCGTGGTTCTGCTCCAGACGAGCCCTTACCACGTTGACTCACTCCTGCAGCTC
AGCGATGCCTGCCGCTTTCAAGAGGATCAGGAGATGGCTCGAGACCTCGTAGAGAGAGCGCTGTACAGCATGGAATGTGCGTTCCACCCC
CTGTTCAGTCTCACCAGTGGGGCCTGCCGGCTGGATTACCGCAGACCCGAGAACAGGAGCTTCTACCTGGCCCTCTACAAGCAGATGAGC
TTCCTGGAGAAGCGAGGCTGCCCGCGCACGGCGCTGGAGTACTGCAAGCTCATCCTGAGTCTCGAGCCGGATGAGGACCCCCTCTGCATG
CTGCTGCTCATCGACCACCTGGCCTTGCGGGCCCGGAACTACGAGTACCTGATCCGCCTCTTCCAGGAGTGGGAGGCTCATCGGAACCTG
TCCCAGCTCCCTAATTTTGCCTTCTCTGTTCCACTGGCGTATTTCCTGCTGAGCCAGCAGACAGACCTCCCTGAGTGTGAGCAGAGCTCT
GCCAGGCAGAAGGCCTCTCTCCTGATACAGCAGGCGCTCACCATGTTCCCTGGAGTCCTCCTGCCCCTGCTCGAGTCTTGCAGTGTGCGG
CCCGACGCCAGCGTTTCCAGTCACCGCTTCTTTGGACCCAATGCTGAAATAAGCCAGCCCCCTGCCCTGAGCCAGCTGGTGAACCTGTAC
CTTGGGAGGTCACACTTTCTCTGGAAAGAGCCCGCCACCATGAGCTGGCTGGAGGAGAACGTCCACGAGGTTCTGCAAGCAGTGGACGCC
GGGGACCCAGCCGTGGAAGCCTGTGAGAACCGGCGGAAGGTGCTCTACCAGCGTGCACCCAGGAATATCCACCGCCATGTGATCCTCTCT
GAGATCAAGGAAGCCGTCGCTGCCCTGCCCCCGGACGTGACCACGCAGTCTGTGATGGGGTTTGATCCTCTGCCTCCTTCGGACACAATC
TACTCCTACGTCAGGCCAGAGAGAGTCTCTGGTAAGAAGAGTGAAAGCAAAGAAGCCAAGAAGTCTGAAGAACCAAGAATTCGGAAGAAG
CCGGGACCCAAGCCCGGATGGAAGAAGAAGCTTCGTTGTGAGAGGGAGGAGCTTCCCACCATCTACAAGTGTCCTTACCAGGGCTGCACG
GCCGTGTACCGAGGCGCTGACGGCATGAAGAAGCACATCAAGGAGCACCACGAGGAGGTCCGGGAGCGGCCCTGCCCCCACCCTGGCTGC
AACAAGGTTTTCATGATCGACCGCTACCTGCAGCGCCACGTGAAGCTCATCCACACAGAGGTGCGGAACTATATCTGTGACGAATGTGGA
CAAACCTTCAAGCAGCGGAAGCACCTTCTCGTCCACCAAATGCGACATTCGGGAGCCAAGCCTTTGCAGTGTGAGGTCTGTGGGTTCCAG
TGCAGGCAGCGGGCATCCCTCAAGTACCACATGACCAAACACAAGGCTGAGACTGAGCTGGACTTTGCCTGTGACCAGTGTGGCCGGCGG
TTTGAGAAGGCCCACAACCTCAATGTACACATGTCCATGGTGCACCCGCTGACACAGACCCAGGACAAGGCCCTGCCCCTGGAGGCGGAA
CCACCACCTGGGCCACCGAGCCCCTCTGTGACCACAGAGGGCCAGGCGGTGAAGCCCGAACCCACCTGAGGACGGCAGTGAGGATGAGCA
CCTCTAGCAGCCTGGACTCCGCAGTGGCTGTGTCAGCCTCACCCTTCGTGTGCACCCGCATGGGAGGGTCGGAGGGTGCTGCCCGCCCTT
GGTGCTGGAGGCGGGCTTGGTGTCCGGCTCAAGTAGCCTTCCTCTGCTCTGGGACCAGTGGTTTATTTTCCCGCAAACGCTGAGTGACTC
GGGGCCGGACAGTTCATAAATAATTGATTCCTTTCCCCACTAAAGCAGTCGAGGAGATTTGTAATCCACTTTTTAGTGCAACAAGAGCTC

>89759_89759_6_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263347_ZNF276_chr16_89799710_ENST00000443381_length(amino acids)=662AA_BP=437
MNRPGPAPLSSRKHVLYVEHRHLNPDTELKRYFGARAILGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEH
SEEYQQAQHKFLVAVESMEPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLVERALYSMECAFHPLFSLTSGACRLDYRRPENRS
FYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQ
TDLPECEQSSARQKASLLIQQALTMFPGVLLPLLESCSVRPDASVSSHRFFGPNAEISQPPALSQLVNLYLGRSHFLWKEPATMSWLEEN
VHEVLQAVDAGDPAVEACENRRKVLYQRAPRNIHRHVILSEIKEAVAALPPDVTTQSVMGFDPLPPSDTIYSYVRPERVSGKKSESKEAK
KSEEPRIRKKPGPKPGWKKKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTE
VRNYICDECGQTFKQRKHLLVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQT

--------------------------------------------------------------
>89759_89759_7_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263347_ZNF276_chr16_89799710_ENST00000446326_length(transcript)=2084nt_BP=1373nt
TAGGAAAACGGACTAGAAGATATCGATCGCATCCTAGAGAGGATTGAGGACAGCACTGGGTTGAACCGTCCCGGCCCAGCTCCCCTGAGC
TCCAGGAAGCACGTTCTCTACGTGGAGCACAGACACTTGAATCCAGACACAGAACTGAAAAGGTATTTTGGTGCCCGGGCAATCCTGGGG
GAGCAAAGGCCACGGCAGAGACAACGTGTGTACCCCAAGTGCACATGGCTGACCACCCCTAAAAGCACCTGGCCCCGCTACAGCAAACCA
GGTCTGTCCATGCGGCTGCTGGAATCAAAAAAAGGCCTCTCCTTCTTTGCGTTTGAGCACAGTGAGGAGTACCAGCAGGCTCAGCACAAG
TTCCTGGTGGCCGTGGAGTCTATGGAGCCGAACAACATCGTGGTTCTGCTCCAGACGAGCCCTTACCACGTTGACTCACTCCTGCAGCTC
AGCGATGCCTGCCGCTTTCAAGAGGATCAGGAGATGGCTCGAGACCTCGTAGAGAGAGCGCTGTACAGCATGGAATGTGCGTTCCACCCC
CTGTTCAGTCTCACCAGTGGGGCCTGCCGGCTGGATTACCGCAGACCCGAGAACAGGAGCTTCTACCTGGCCCTCTACAAGCAGATGAGC
TTCCTGGAGAAGCGAGGCTGCCCGCGCACGGCGCTGGAGTACTGCAAGCTCATCCTGAGTCTCGAGCCGGATGAGGACCCCCTCTGCATG
CTGCTGCTCATCGACCACCTGGCCTTGCGGGCCCGGAACTACGAGTACCTGATCCGCCTCTTCCAGGAGTGGGAGGCTCATCGGAACCTG
TCCCAGCTCCCTAATTTTGCCTTCTCTGTTCCACTGGCGTATTTCCTGCTGAGCCAGCAGACAGACCTCCCTGAGTGTGAGCAGAGCTCT
GCCAGGCAGAAGGCCTCTCTCCTGATACAGCAGGCGCTCACCATGTTCCCTGGAGTCCTCCTGCCCCTGCTCGAGTCTTGCAGTGTGCGG
CCCGACGCCAGCGTTTCCAGTCACCGCTTCTTTGGACCCAATGCTGAAATAAGCCAGCCCCCTGCCCTGAGCCAGCTGGTGAACCTGTAC
CTTGGGAGGTCACACTTTCTCTGGAAAGAGCCCGCCACCATGAGCTGGCTGGAGGAGAACGTCCACGAGGTTCTGCAAGCAGTGGACGCC
GGGGACCCAGCCGTGGAAGCCTGTGAGAACCGGCGGAAGGTGCTCTACCAGCGTGCACCCAGGAATATCCACCGCCATGTGATCCTCTCT
GAGATCAAGGAAGCCGTCGCTGCCCTGCCCCCGGACGTGACCACGCAGTCTGTGATGGGGTTTGATCCTCTGCCTCCTTCGGACACAATC
TACTCCTACGTCAGGCCAGAGAGAGTCTCTGGTAAGAAGAGTGAAAGCAAAGAAGCCAAGAAGTCTGAAGAACCAAGAATTCGGAAGAAG
CCGGGACCCAAGCCCGGATGGAAGAAGAAGCTTCGTTGTGAGAGGGAGGAGCTTCCCACCATCTACAAGTGTCCTTACCAGGGCTGCACG
GCCGTGTACCGAGGCGCTGACGGCATGAAGAAGCACATCAAGGAGCACCACGAGGAGGTCCGGGAGCGGCCCTGCCCCCACCCTGGCTGC
AACAAGGTTTTCATGATCGACCGCTACCTGCAGCGCCACGTGAAGCTCATCCACACAGAGGTGCGGAACTATATCTGTGACGAATGTGGA
CAAACCTTCAAGCAGCGGAAGCACCTTCTCGTCCACCAAATGCGACATTCGGGAGCCAAGCCTTTGCAGTGTGAGGTCTGTGGGTTCCAG
TGCAGGCAGCGGGCATCCCTCAAGTACCACATGACCAAACACAAGGCTGAGACTGAGCTGGACTTTGCCTGTGACCAGTGTGGCCGGCGG
TTTGAGAAGGCCCACAACCTCAATGTACACATGTCCATGGTGCACCCGCTGACACAGACCCAGGACAAGGCCCTGCCCCTGGAGGCGGAA
CCACCACCTGGGCCACCGAGCCCCTCTGTGACCACAGAGGGCCAGGCGGTGAAGCCCGAACCCACCTGAGGACGGCAGTGAGGATGAGCA

>89759_89759_7_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263347_ZNF276_chr16_89799710_ENST00000446326_length(amino acids)=662AA_BP=437
MNRPGPAPLSSRKHVLYVEHRHLNPDTELKRYFGARAILGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEH
SEEYQQAQHKFLVAVESMEPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLVERALYSMECAFHPLFSLTSGACRLDYRRPENRS
FYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQ
TDLPECEQSSARQKASLLIQQALTMFPGVLLPLLESCSVRPDASVSSHRFFGPNAEISQPPALSQLVNLYLGRSHFLWKEPATMSWLEEN
VHEVLQAVDAGDPAVEACENRRKVLYQRAPRNIHRHVILSEIKEAVAALPPDVTTQSVMGFDPLPPSDTIYSYVRPERVSGKKSESKEAK
KSEEPRIRKKPGPKPGWKKKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTE
VRNYICDECGQTFKQRKHLLVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQT

--------------------------------------------------------------
>89759_89759_8_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263347_ZNF276_chr16_89799710_ENST00000568064_length(transcript)=2393nt_BP=1373nt
TAGGAAAACGGACTAGAAGATATCGATCGCATCCTAGAGAGGATTGAGGACAGCACTGGGTTGAACCGTCCCGGCCCAGCTCCCCTGAGC
TCCAGGAAGCACGTTCTCTACGTGGAGCACAGACACTTGAATCCAGACACAGAACTGAAAAGGTATTTTGGTGCCCGGGCAATCCTGGGG
GAGCAAAGGCCACGGCAGAGACAACGTGTGTACCCCAAGTGCACATGGCTGACCACCCCTAAAAGCACCTGGCCCCGCTACAGCAAACCA
GGTCTGTCCATGCGGCTGCTGGAATCAAAAAAAGGCCTCTCCTTCTTTGCGTTTGAGCACAGTGAGGAGTACCAGCAGGCTCAGCACAAG
TTCCTGGTGGCCGTGGAGTCTATGGAGCCGAACAACATCGTGGTTCTGCTCCAGACGAGCCCTTACCACGTTGACTCACTCCTGCAGCTC
AGCGATGCCTGCCGCTTTCAAGAGGATCAGGAGATGGCTCGAGACCTCGTAGAGAGAGCGCTGTACAGCATGGAATGTGCGTTCCACCCC
CTGTTCAGTCTCACCAGTGGGGCCTGCCGGCTGGATTACCGCAGACCCGAGAACAGGAGCTTCTACCTGGCCCTCTACAAGCAGATGAGC
TTCCTGGAGAAGCGAGGCTGCCCGCGCACGGCGCTGGAGTACTGCAAGCTCATCCTGAGTCTCGAGCCGGATGAGGACCCCCTCTGCATG
CTGCTGCTCATCGACCACCTGGCCTTGCGGGCCCGGAACTACGAGTACCTGATCCGCCTCTTCCAGGAGTGGGAGGCTCATCGGAACCTG
TCCCAGCTCCCTAATTTTGCCTTCTCTGTTCCACTGGCGTATTTCCTGCTGAGCCAGCAGACAGACCTCCCTGAGTGTGAGCAGAGCTCT
GCCAGGCAGAAGGCCTCTCTCCTGATACAGCAGGCGCTCACCATGTTCCCTGGAGTCCTCCTGCCCCTGCTCGAGTCTTGCAGTGTGCGG
CCCGACGCCAGCGTTTCCAGTCACCGCTTCTTTGGACCCAATGCTGAAATAAGCCAGCCCCCTGCCCTGAGCCAGCTGGTGAACCTGTAC
CTTGGGAGGTCACACTTTCTCTGGAAAGAGCCCGCCACCATGAGCTGGCTGGAGGAGAACGTCCACGAGGTTCTGCAAGCAGTGGACGCC
GGGGACCCAGCCGTGGAAGCCTGTGAGAACCGGCGGAAGGTGCTCTACCAGCGTGCACCCAGGAATATCCACCGCCATGTGATCCTCTCT
GAGATCAAGGAAGCCGTCGCTGCCCTGCCCCCGGACGTGACCACGCAGTCTGTGATGGGGTTTGATCCTCTGCCTCCTTCGGACACAATC
TACTCCTACGTCAGGCCAGAGAGAGTCTCTGGTAAGAAGAGTGAAAGCAAAGAAGCCAAGAAGTCTGAAGAACCAAGAATTCGGAAGAAG
CCGGGACCCAAGCCCGGATGGAAGAAGAAGCTTCGTTGTGAGAGGGAGGAGCTTCCCACCATCTACAAGTGTCCTTACCAGGGCTGCACG
GCCGTGTACCGAGGCGCTGACGGCATGAAGAAGCACATCAAGGAGCACCACGAGGAGGTCCGGGAGCGGCCCTGCCCCCACCCTGGCTGC
AACAAGGTTTTCATGATCGACCGCTACCTGCAGCGCCACGTGAAGCTCATCCACACAGAGGTGCGGAACTATATCTGTGACGAATGTGGA
CAAACCTTCAAGCAGCGGAAGCACCTTCTCGTCCACCAAATGCGACATTCGGGAGCCAAGCCTTTGCAGTAAGTGTGAGTCAGGACCCCC
TCCCAGGGCTGTGGCCCTCGCACCTTCTTATCTGCCTCTGTCCCCCAGGTGTGAGGTCTGTGGGTTCCAGTGCAGGCAGCGGGCATCCCT
CAAGTACCACATGACCAAACACAAGGCTGAGACTGAGCTGGACTTTGCCTGTGACCAGTGTGGCCGGCGGTTTGAGAAGGCCCACAACCT
CAATGTACACATGTCCATGGTGCACCCGCTGACACAGACCCAGGACAAGGCCCTGCCCCTGGAGGCGGAACCACCACCTGGGCCACCGAG
CCCCTCTGTGACCACAGAGGGCCAGGCGGTGAAGCCCGAACCCACCTGAGGACGGCAGTGAGGATGAGCACCTCTAGCAGCCTGGACTCC
GCAGTGGCTGTGTCAGCCTCACCCTTCGTGTGCACCCGCATGGGAGGGTCGGAGGGTGCTGCCCGCCCTTGGTGCTGGAGGCGGGCTTGG
TGTCCGGCTCAAGTAGCCTTCCTCTGCTCTGGGACCAGTGGTTTATTTTCCCGCAAACGCTGAGTGACTCGGGGCCGGACAGTTCATAAA

>89759_89759_8_TCF25-ZNF276_TCF25_chr16_89973730_ENST00000263347_ZNF276_chr16_89799710_ENST00000568064_length(amino acids)=573AA_BP=437
MNRPGPAPLSSRKHVLYVEHRHLNPDTELKRYFGARAILGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEH
SEEYQQAQHKFLVAVESMEPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLVERALYSMECAFHPLFSLTSGACRLDYRRPENRS
FYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQ
TDLPECEQSSARQKASLLIQQALTMFPGVLLPLLESCSVRPDASVSSHRFFGPNAEISQPPALSQLVNLYLGRSHFLWKEPATMSWLEEN
VHEVLQAVDAGDPAVEACENRRKVLYQRAPRNIHRHVILSEIKEAVAALPPDVTTQSVMGFDPLPPSDTIYSYVRPERVSGKKSESKEAK
KSEEPRIRKKPGPKPGWKKKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TCF25-ZNF276


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TCF25-ZNF276


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TCF25-ZNF276


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource