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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TCF3-SYTL5 (FusionGDB2 ID:89779)

Fusion Gene Summary for TCF3-SYTL5

check button Fusion gene summary
Fusion gene informationFusion gene name: TCF3-SYTL5
Fusion gene ID: 89779
HgeneTgene
Gene symbol

TCF3

SYTL5

Gene ID

83439

94122

Gene nametranscription factor 7 like 1synaptotagmin like 5
SynonymsTCF-3|TCF3slp5
Cytomap

2p11.2

Xp11.4

Type of geneprotein-codingprotein-coding
Descriptiontranscription factor 7-like 1HMG box transcription factor 3transcription factor 7-like 1 (T-cell specific, HMG-box)synaptotagmin-like protein 5exophilin 9
Modification date2020031320200313
UniProtAcc

TFPT

.
Ensembl transtripts involved in fusion geneENST00000262965, ENST00000344749, 
ENST00000395423, ENST00000453954, 
ENST00000588136, 		ENST00000297875, 
ENST00000357972, ENST00000456733, 
Fusion gene scores* DoF score21 X 26 X 9=49142 X 3 X 2=12
# samples 273
** MAII scorelog2(27/4914*10)=-4.18586654531133
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/12*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: TCF3 [Title/Abstract] AND SYTL5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTCF3(1615284)-SYTL5(37985841), # samples:3
Anticipated loss of major functional domain due to fusion event.TCF3-SYTL5 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
TCF3-SYTL5 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
TCF3-SYTL5 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across TCF3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SYTL5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AR-A0U3-01ATCF3chr19

1615284

-SYTL5chrX

37985841

+
ChimerDB4BRCATCGA-AR-A0U3-01ATCF3chr19

1615685

-SYTL5chrX

37985841

+
ChimerDB4BRCATCGA-AR-A0U3TCF3chr19

1615283

-SYTL5chrX

37985840

+
ChimerDB4BRCATCGA-AR-A0U3TCF3chr19

1615684

-SYTL5chrX

37985840

+


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Fusion Gene ORF analysis for TCF3-SYTL5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000262965ENST00000297875TCF3chr19

1615685

-SYTL5chrX

37985841

+
Frame-shiftENST00000262965ENST00000297875TCF3chr19

1615684

-SYTL5chrX

37985840

+
Frame-shiftENST00000262965ENST00000357972TCF3chr19

1615685

-SYTL5chrX

37985841

+
Frame-shiftENST00000262965ENST00000357972TCF3chr19

1615684

-SYTL5chrX

37985840

+
Frame-shiftENST00000262965ENST00000456733TCF3chr19

1615685

-SYTL5chrX

37985841

+
Frame-shiftENST00000262965ENST00000456733TCF3chr19

1615684

-SYTL5chrX

37985840

+
Frame-shiftENST00000344749ENST00000297875TCF3chr19

1615685

-SYTL5chrX

37985841

+
Frame-shiftENST00000344749ENST00000297875TCF3chr19

1615684

-SYTL5chrX

37985840

+
Frame-shiftENST00000344749ENST00000357972TCF3chr19

1615685

-SYTL5chrX

37985841

+
Frame-shiftENST00000344749ENST00000357972TCF3chr19

1615684

-SYTL5chrX

37985840

+
Frame-shiftENST00000344749ENST00000456733TCF3chr19

1615685

-SYTL5chrX

37985841

+
Frame-shiftENST00000344749ENST00000456733TCF3chr19

1615684

-SYTL5chrX

37985840

+
Frame-shiftENST00000395423ENST00000297875TCF3chr19

1615284

-SYTL5chrX

37985841

+
Frame-shiftENST00000395423ENST00000297875TCF3chr19

1615283

-SYTL5chrX

37985840

+
Frame-shiftENST00000395423ENST00000357972TCF3chr19

1615284

-SYTL5chrX

37985841

+
Frame-shiftENST00000395423ENST00000357972TCF3chr19

1615283

-SYTL5chrX

37985840

+
Frame-shiftENST00000395423ENST00000456733TCF3chr19

1615284

-SYTL5chrX

37985841

+
Frame-shiftENST00000395423ENST00000456733TCF3chr19

1615283

-SYTL5chrX

37985840

+
Frame-shiftENST00000453954ENST00000297875TCF3chr19

1615685

-SYTL5chrX

37985841

+
Frame-shiftENST00000453954ENST00000297875TCF3chr19

1615684

-SYTL5chrX

37985840

+
Frame-shiftENST00000453954ENST00000357972TCF3chr19

1615685

-SYTL5chrX

37985841

+
Frame-shiftENST00000453954ENST00000357972TCF3chr19

1615684

-SYTL5chrX

37985840

+
Frame-shiftENST00000453954ENST00000456733TCF3chr19

1615685

-SYTL5chrX

37985841

+
Frame-shiftENST00000453954ENST00000456733TCF3chr19

1615684

-SYTL5chrX

37985840

+
Frame-shiftENST00000588136ENST00000297875TCF3chr19

1615685

-SYTL5chrX

37985841

+
Frame-shiftENST00000588136ENST00000297875TCF3chr19

1615684

-SYTL5chrX

37985840

+
Frame-shiftENST00000588136ENST00000357972TCF3chr19

1615685

-SYTL5chrX

37985841

+
Frame-shiftENST00000588136ENST00000357972TCF3chr19

1615684

-SYTL5chrX

37985840

+
Frame-shiftENST00000588136ENST00000456733TCF3chr19

1615685

-SYTL5chrX

37985841

+
Frame-shiftENST00000588136ENST00000456733TCF3chr19

1615684

-SYTL5chrX

37985840

+
In-frameENST00000262965ENST00000297875TCF3chr19

1615284

-SYTL5chrX

37985841

+
In-frameENST00000262965ENST00000297875TCF3chr19

1615283

-SYTL5chrX

37985840

+
In-frameENST00000262965ENST00000357972TCF3chr19

1615284

-SYTL5chrX

37985841

+
In-frameENST00000262965ENST00000357972TCF3chr19

1615283

-SYTL5chrX

37985840

+
In-frameENST00000262965ENST00000456733TCF3chr19

1615284

-SYTL5chrX

37985841

+
In-frameENST00000262965ENST00000456733TCF3chr19

1615283

-SYTL5chrX

37985840

+
intron-3CDSENST00000344749ENST00000297875TCF3chr19

1615284

-SYTL5chrX

37985841

+
intron-3CDSENST00000344749ENST00000297875TCF3chr19

1615283

-SYTL5chrX

37985840

+
intron-3CDSENST00000344749ENST00000357972TCF3chr19

1615284

-SYTL5chrX

37985841

+
intron-3CDSENST00000344749ENST00000357972TCF3chr19

1615283

-SYTL5chrX

37985840

+
intron-3CDSENST00000344749ENST00000456733TCF3chr19

1615284

-SYTL5chrX

37985841

+
intron-3CDSENST00000344749ENST00000456733TCF3chr19

1615283

-SYTL5chrX

37985840

+
intron-3CDSENST00000395423ENST00000297875TCF3chr19

1615685

-SYTL5chrX

37985841

+
intron-3CDSENST00000395423ENST00000297875TCF3chr19

1615684

-SYTL5chrX

37985840

+
intron-3CDSENST00000395423ENST00000357972TCF3chr19

1615685

-SYTL5chrX

37985841

+
intron-3CDSENST00000395423ENST00000357972TCF3chr19

1615684

-SYTL5chrX

37985840

+
intron-3CDSENST00000395423ENST00000456733TCF3chr19

1615685

-SYTL5chrX

37985841

+
intron-3CDSENST00000395423ENST00000456733TCF3chr19

1615684

-SYTL5chrX

37985840

+
intron-3CDSENST00000453954ENST00000297875TCF3chr19

1615284

-SYTL5chrX

37985841

+
intron-3CDSENST00000453954ENST00000297875TCF3chr19

1615283

-SYTL5chrX

37985840

+
intron-3CDSENST00000453954ENST00000357972TCF3chr19

1615284

-SYTL5chrX

37985841

+
intron-3CDSENST00000453954ENST00000357972TCF3chr19

1615283

-SYTL5chrX

37985840

+
intron-3CDSENST00000453954ENST00000456733TCF3chr19

1615284

-SYTL5chrX

37985841

+
intron-3CDSENST00000453954ENST00000456733TCF3chr19

1615283

-SYTL5chrX

37985840

+
intron-3CDSENST00000588136ENST00000297875TCF3chr19

1615284

-SYTL5chrX

37985841

+
intron-3CDSENST00000588136ENST00000297875TCF3chr19

1615283

-SYTL5chrX

37985840

+
intron-3CDSENST00000588136ENST00000357972TCF3chr19

1615284

-SYTL5chrX

37985841

+
intron-3CDSENST00000588136ENST00000357972TCF3chr19

1615283

-SYTL5chrX

37985840

+
intron-3CDSENST00000588136ENST00000456733TCF3chr19

1615284

-SYTL5chrX

37985841

+
intron-3CDSENST00000588136ENST00000456733TCF3chr19

1615283

-SYTL5chrX

37985840

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000262965TCF3chr191615284-ENST00000297875SYTL5chrX37985841+439621673452309654
ENST00000262965TCF3chr191615284-ENST00000357972SYTL5chrX37985841+439921673452309654
ENST00000262965TCF3chr191615284-ENST00000456733SYTL5chrX37985841+439921673452309654
ENST00000262965TCF3chr191615283-ENST00000297875SYTL5chrX37985840+439621673452309654
ENST00000262965TCF3chr191615283-ENST00000357972SYTL5chrX37985840+439921673452309654
ENST00000262965TCF3chr191615283-ENST00000456733SYTL5chrX37985840+439921673452309654

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000262965ENST00000297875TCF3chr191615284-SYTL5chrX37985841+0.017588160.9824118
ENST00000262965ENST00000357972TCF3chr191615284-SYTL5chrX37985841+0.0175894050.98241067
ENST00000262965ENST00000456733TCF3chr191615284-SYTL5chrX37985841+0.0175894050.98241067
ENST00000262965ENST00000297875TCF3chr191615283-SYTL5chrX37985840+0.017588160.9824118
ENST00000262965ENST00000357972TCF3chr191615283-SYTL5chrX37985840+0.0175894050.98241067
ENST00000262965ENST00000456733TCF3chr191615283-SYTL5chrX37985840+0.0175894050.98241067

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Fusion Genomic Features for TCF3-SYTL5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TCF3chr191615684-SYTL5chrX37985840+0.69096010.3090399
TCF3chr191615684-SYTL5chrX37985840+0.69096010.3090399
TCF3chr191615283-SYTL5chrX37985840+0.0103426190.98965734
TCF3chr191615283-SYTL5chrX37985840+0.0103426190.98965734
TCF3chr191615684-SYTL5chrX37985840+0.69096010.3090399
TCF3chr191615684-SYTL5chrX37985840+0.69096010.3090399
TCF3chr191615283-SYTL5chrX37985840+0.0103426190.98965734
TCF3chr191615283-SYTL5chrX37985840+0.0103426190.98965734

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for TCF3-SYTL5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:1615284/chrX:37985841)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
TCF3

TFPT

.
253FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTCF3chr19:1615283chrX:37985840ENST00000262965-1819549_602607655.0DomainbHLH
HgeneTCF3chr19:1615284chrX:37985841ENST00000262965-1819549_602607655.0DomainbHLH
HgeneTCF3chr19:1615283chrX:37985840ENST00000262965-1819170_176607655.0MotifNuclear localization signal
HgeneTCF3chr19:1615283chrX:37985840ENST00000262965-181919_27607655.0MotifNote=9aaTAD
HgeneTCF3chr19:1615284chrX:37985841ENST00000262965-1819170_176607655.0MotifNuclear localization signal
HgeneTCF3chr19:1615284chrX:37985841ENST00000262965-181919_27607655.0MotifNote=9aaTAD
HgeneTCF3chr19:1615283chrX:37985840ENST00000262965-1819389_425607655.0RegionNote=Leucine-zipper
HgeneTCF3chr19:1615284chrX:37985841ENST00000262965-1819389_425607655.0RegionNote=Leucine-zipper

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTCF3chr19:1615283chrX:37985840ENST00000344749-119549_6020652.0DomainbHLH
HgeneTCF3chr19:1615283chrX:37985840ENST00000588136-119549_6020527.0DomainbHLH
HgeneTCF3chr19:1615284chrX:37985841ENST00000344749-119549_6020652.0DomainbHLH
HgeneTCF3chr19:1615284chrX:37985841ENST00000588136-119549_6020527.0DomainbHLH
HgeneTCF3chr19:1615283chrX:37985840ENST00000344749-119170_1760652.0MotifNuclear localization signal
HgeneTCF3chr19:1615283chrX:37985840ENST00000344749-11919_270652.0MotifNote=9aaTAD
HgeneTCF3chr19:1615283chrX:37985840ENST00000588136-119170_1760527.0MotifNuclear localization signal
HgeneTCF3chr19:1615283chrX:37985840ENST00000588136-11919_270527.0MotifNote=9aaTAD
HgeneTCF3chr19:1615284chrX:37985841ENST00000344749-119170_1760652.0MotifNuclear localization signal
HgeneTCF3chr19:1615284chrX:37985841ENST00000344749-11919_270652.0MotifNote=9aaTAD
HgeneTCF3chr19:1615284chrX:37985841ENST00000588136-119170_1760527.0MotifNuclear localization signal
HgeneTCF3chr19:1615284chrX:37985841ENST00000588136-11919_270527.0MotifNote=9aaTAD
HgeneTCF3chr19:1615283chrX:37985840ENST00000344749-119389_4250652.0RegionNote=Leucine-zipper
HgeneTCF3chr19:1615283chrX:37985840ENST00000588136-119389_4250527.0RegionNote=Leucine-zipper
HgeneTCF3chr19:1615284chrX:37985841ENST00000344749-119389_4250652.0RegionNote=Leucine-zipper
HgeneTCF3chr19:1615284chrX:37985841ENST00000588136-119389_4250527.0RegionNote=Leucine-zipper
TgeneSYTL5chr19:1615283chrX:37985840ENST000002978751517406_527683731.0DomainC2 1
TgeneSYTL5chr19:1615283chrX:37985840ENST000002978751517563_694683731.0DomainC2 2
TgeneSYTL5chr19:1615283chrX:37985840ENST0000029787515177_123683731.0DomainRabBD
TgeneSYTL5chr19:1615283chrX:37985840ENST000003579721517406_527683731.0DomainC2 1
TgeneSYTL5chr19:1615283chrX:37985840ENST000003579721517563_694683731.0DomainC2 2
TgeneSYTL5chr19:1615283chrX:37985840ENST0000035797215177_123683731.0DomainRabBD
TgeneSYTL5chr19:1615283chrX:37985840ENST000004567331517406_527705753.0DomainC2 1
TgeneSYTL5chr19:1615283chrX:37985840ENST000004567331517563_694705753.0DomainC2 2
TgeneSYTL5chr19:1615283chrX:37985840ENST0000045673315177_123705753.0DomainRabBD
TgeneSYTL5chr19:1615284chrX:37985841ENST000002978751517406_527683731.0DomainC2 1
TgeneSYTL5chr19:1615284chrX:37985841ENST000002978751517563_694683731.0DomainC2 2
TgeneSYTL5chr19:1615284chrX:37985841ENST0000029787515177_123683731.0DomainRabBD
TgeneSYTL5chr19:1615284chrX:37985841ENST000003579721517406_527683731.0DomainC2 1
TgeneSYTL5chr19:1615284chrX:37985841ENST000003579721517563_694683731.0DomainC2 2
TgeneSYTL5chr19:1615284chrX:37985841ENST0000035797215177_123683731.0DomainRabBD
TgeneSYTL5chr19:1615284chrX:37985841ENST000004567331517406_527705753.0DomainC2 1
TgeneSYTL5chr19:1615284chrX:37985841ENST000004567331517563_694705753.0DomainC2 2
TgeneSYTL5chr19:1615284chrX:37985841ENST0000045673315177_123705753.0DomainRabBD
TgeneSYTL5chr19:1615283chrX:37985840ENST00000297875151764_106683731.0Zinc fingerNote=FYVE-type
TgeneSYTL5chr19:1615283chrX:37985840ENST00000357972151764_106683731.0Zinc fingerNote=FYVE-type
TgeneSYTL5chr19:1615283chrX:37985840ENST00000456733151764_106705753.0Zinc fingerNote=FYVE-type
TgeneSYTL5chr19:1615284chrX:37985841ENST00000297875151764_106683731.0Zinc fingerNote=FYVE-type
TgeneSYTL5chr19:1615284chrX:37985841ENST00000357972151764_106683731.0Zinc fingerNote=FYVE-type
TgeneSYTL5chr19:1615284chrX:37985841ENST00000456733151764_106705753.0Zinc fingerNote=FYVE-type


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Fusion Gene Sequence for TCF3-SYTL5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>89779_89779_1_TCF3-SYTL5_TCF3_chr19_1615283_ENST00000262965_SYTL5_chrX_37985840_ENST00000297875_length(transcript)=4396nt_BP=2167nt
TCCCGCCGCAGGAAGATGAGGCAGCGGCGGCGGCTGCGGGCGTAGCGGGCCGGAGCCGACGCGGCGGCGGGCACCGCGGGCACCGCGCAC
GCCGCTGCCCCAGGGGCGCCCCGGCCGGCCGCGCGCACGGGCCCCGCGGGACGGGCCACGCGGGGGTGGGAGGGGCCCGGGCCACGCGCG
CCGCCGCCGCCGCCCACGCGCGACCCTCGGGGGCCCGGCCGCGACGCACCTTTGTCCGGGGGGGGGCCCCCCCGCTTCATGCCGCCGCCC
CCCCCCACGCGCCGCGTGCCCGGCCGCGCCCAGCAGGGTTTCCAGGCCTGAGGTGCCCGCCCTGGCCCCAGGAGAATGAACCAGCCGCAG
AGGATGGCGCCTGTGGGCACAGACAAGGAGCTCAGTGACCTCCTGGACTTCAGCATGATGTTCCCGCTGCCTGTCACCAACGGGAAGGGC
CGGCCCGCCTCCCTGGCCGGGGCGCAGTTCGGAGGTTCAGGTCTTGAGGACCGGCCCAGCTCAGGCTCCTGGGGCAGCGGCGACCAGAGC
AGCTCCTCCTTTGACCCCAGCCGGACCTTCAGCGAGGGCACCCACTTCACTGAGTCGCACAGCAGCCTCTCTTCATCCACATTCCTGGGA
CCGGGACTCGGAGGCAAGAGCGGTGAGCGGGGCGCCTATGCCTCCTTCGGGAGAGACGCAGGCGTGGGCGGCCTGACTCAGGCTGGCTTC
CTGTCAGGCGAGCTGGCCCTCAACAGCCCCGGGCCCCTGTCCCCTTCGGGCATGAAGGGGACCTCCCAGTACTACCCCTCCTACTCCGGC
AGCTCCCGGCGGAGAGCGGCAGACGGCAGCCTAGACACGCAGCCCAAGAAGGTCCGGAAGGTCCCGCCGGGTCTTCCATCCTCGGTGTAC
CCACCCAGCTCAGGTGAGGACTACGGCAGGGATGCCACCGCCTACCCGTCCGCCAAGACCCCCAGCAGCACCTATCCCGCCCCCTTCTAC
GTGGCAGATGGCAGCCTGCACCCCTCAGCCGAGCTCTGGAGTCCCCCGGGCCAGGCGGGCTTCGGGCCCATGCTGGGTGGGGGCTCATCC
CCGCTGCCCCTCCCGCCCGGTAGCGGCCCGGTGGGCAGCAGTGGAAGCAGCAGCACGTTTGGTGGCCTGCACCAGCACGAGCGTATGGGC
TACCAGCTGCATGGAGCAGAGGTGAACGGTGGGCTCCCATCTGCATCCTCCTTCTCCTCAGCCCCCGGAGCCACGTACGGCGGCGTCTCC
AGCCACACGCCGCCTGTCAGCGGGGCCGACAGCCTCCTGGGCTCCCGAGGGACCACAGCTGGCAGCTCCGGGGATGCCCTCGGCAAAGCA
CTGGCCTCGATCTACTCCCCGGATCACTCAAGCAATAACTTCTCGTCCAGCCCTTCTACCCCCGTGGGCTCCCCCCAGGGCCTGGCAGGA
ACGTCACAGTGGCCTCGAGCAGGAGCCCCCGGTGCCTTATCGCCCAGCTACGACGGGGGTCTCCACGGCCTGCAGAGTAAGATAGAAGAC
CACCTGGACGAGGCCATCCACGTGCTCCGCAGCCACGCCGTGGGCACAGCCGGCGACATGCACACGCTGCTGCCTGGCCACGGGGCGCTG
GCCTCAGGTTTCACCGGCCCCATGTCACTGGGCGGGCGGCACGCAGGCCTGGTTGGAGGCAGCCACCCCGAGGACGGCCTCGCAGGCAGC
ACCAGCCTCATGCACAACCACGCGGCCCTCCCCAGCCAGCCAGGCACCCTCCCTGACCTGTCTCGGCCTCCCGACTCCTACAGTGGGCTA
GGGCGAGCAGGTGCCACGGCGGCCGCCAGCGAGATCAAGCGGGAGGAGAAGGAGGACGAGGAGAACACGTCAGCGGCTGACCACTCGGAG
GAGGAGAAGAAGGAGCTGAAGGCCCCCCGGGCCCGGACCAGCCCAGACGAGGACGAGGACGACCTTCTCCCCCCAGAGCAGAAGGCCGAG
CGGGAGAAGGAGCGCCGGGTGGCCAATAACGCCCGGGAGCGGCTGCGGGTCCGTGACATCAACGAGGCCTTTAAGGAGCTGGGGCGCATG
TGCCAACTGCACCTCAACAGCGAGAAGCCCCAGACCAAACTGCTCATCCTGCACCAGGCTGTCTCGGTCATCCTGAACTTGGAGCAGCAA
GTGCGAGGTGTGAGCCATGGGAAGAACGTGGATTGGATGGACTCTCAGGGGGAAGAGCAGCGCCTTTGGCAGAAGATGGCCAACAACCCT
GGAACTCCCTTTGAGGGTGTACTCATGCTTCGTTCCAGCATGGGAAAATGTAGGCTCTAAAGGGACCAGTTCTCCAAGAATGAGGCCACC
AGGACCTATCTGGCTGTCTTTTCCTACCATTAGCAAACTGAGACCTGGGATTCTGCTTCCCTGCCATTTCTCACCTGACAGTGTTGGGAC
ATGAGGGGAGAGATGTCAGTAGTATGAACATTTAGGGTCTTGCTGAGTGCCTAAAAAACATATATTTCCATCCAATCAAGGCCTTCTTGA
TTGGATGATAGAAAGTGTACTACTTGTCCTGTCAACAAGCAAATTGTGCAAAGGCTTATAGGGTTTATGCCATAAAAGAAATGGCACAAG
CCTCCATTTGCTAATTATAAGTTACTTTAGATTTCCTCAAATCCTTTGAAGAGAAAGAGGACCACTGAGAAGGTAGATCACTTGAAAAGT
CAGAAGAAAGGATACTGGCCAACTTTTACTCACCCTAGGAATCCACATGATCTCAAGAAGGCATGGTGGAGATGGTTGCTTGAGCAAGGG
GATTGTCCTGTTATTGCAGCAAACTTGTGGATTAACCAAGTAGTATTTCAAGATGGATTGACAGGGCTTTCTATGATTACTATAGAATTT
ATCATCTAAATCAGTTTACTTTTTAGAACAAAGAGAGCTAAATAACTACATCAGAACGATTGATGTTGATTAGAATTGACCTGGGAAAAT
TGGGATGTAGGGTCACCCTACTGATGACCTAAGAGAGCTCTGTTTTAAACATTTATTTTATAAAATGTTCTAAGCCATTAACTAAAAGGA
AATGAGATATAATGGTCAATTGATATACCTTTTCACATTGTGTTCACTGACGAGACTAGTTTAATGAAAAAGGAGGTACTCTACCTGCTA
TTTTACTTCTGTTCCTCTTCTGCCCTGTTATGGGAGAGAATCAAAGACTCCATCTGCTCTCTTCCCCCTTGTTTTCTCCTTCACTGAGTT
TTTCTTATCTCCTTTTGCAGTGGTTAACTATTGTCACAATAATGCTGAATGAAAAAACACACCAAATGTCAGTGGCTTAAAATGACCATC
CTTTTTCTCACAGTTATGAAGATTGGCTATGGCACCTCTGCTTCCTGCTATAGGCCTGAGGTTCTAGGGCTTCTTATGCCTCATCCTCTT
TAAGCCAAAGGGATAGCCAGAGCATCTTGATGGCAGAAGTGCAATAAGATGAGCCCCACTGCTCGGGTACATTTTCAGCCCCTGGTTGTG
TCATGTCTACTGATATCTCATTGGTCAAAGGAAGTCAGAGGGCCAAGATGAAGAGGCAGGGAAATATGCACTGCCCACAGTGAAGCCATG
ACAAGAGTGAGGATGCAGGAAGGCATGAAGAATTGGGGCCAACAGTTCAATCTACCATACCTTCTCTCACCTGGAATTCCAGATGCTTGA
GCTACGAAACTTAGATGCAAAGAAAGTTAAAGCTAGAAGGAACCTCAGGCCCAGTTGCTCATTTTGCAGATTCCAAATGTGAATTTCAGA
GAGCTGAGATAACTTGCCCAAGGCCATATAGAGGCTGTGACTAAATCTGGACTTAAATCCAGACTATCAATCTTAGGCCAGTGTTCTTTT
TTCAATATAGTCCTTGGCATAATGCTATGCTTATTAGGTAGATAAAAGGGCTTATGTCAAGAAATTTGGAGCAGAGTCTGATTACTTGAG
CATGAACATACCCGACCAAGGTATGTTCTGGAGTCATATTCTAGCCTCTGAGCTCATTTTTTCATGCGAGTTCATATAAAATCCTCGAAA
GTTTAGAAACTAGGTTTTAGTAGTAACGGAGCTAGAATCATCTTCGGGCTTATTCCTGCTAGTTGTTCCATATTTCTAGATTTCATCTTG
AATTTTGAAAACTGATTTAAGAATATATTTAGTATTATTATTAGTAAGGGAATACGCAATCCAGTTTCAATTTTATTCAGAAGTAGGTCA
CCTAATTCTAGAAAATGGTTATTAGTCTAGTGTCGCTTAGCAAGGTACTTAAAAGAAAATCTGCACATATCCTTGTGCTGCCCTTCTTAA

>89779_89779_1_TCF3-SYTL5_TCF3_chr19_1615283_ENST00000262965_SYTL5_chrX_37985840_ENST00000297875_length(amino acids)=654AA_BP=607
MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSS
STFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGL
PSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQ
HERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP
QGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPED
GLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSPDEDEDDLLPP
EQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRGVSHGKNVDWMDSQGEEQRLWQK

--------------------------------------------------------------
>89779_89779_2_TCF3-SYTL5_TCF3_chr19_1615283_ENST00000262965_SYTL5_chrX_37985840_ENST00000357972_length(transcript)=4399nt_BP=2167nt
TCCCGCCGCAGGAAGATGAGGCAGCGGCGGCGGCTGCGGGCGTAGCGGGCCGGAGCCGACGCGGCGGCGGGCACCGCGGGCACCGCGCAC
GCCGCTGCCCCAGGGGCGCCCCGGCCGGCCGCGCGCACGGGCCCCGCGGGACGGGCCACGCGGGGGTGGGAGGGGCCCGGGCCACGCGCG
CCGCCGCCGCCGCCCACGCGCGACCCTCGGGGGCCCGGCCGCGACGCACCTTTGTCCGGGGGGGGGCCCCCCCGCTTCATGCCGCCGCCC
CCCCCCACGCGCCGCGTGCCCGGCCGCGCCCAGCAGGGTTTCCAGGCCTGAGGTGCCCGCCCTGGCCCCAGGAGAATGAACCAGCCGCAG
AGGATGGCGCCTGTGGGCACAGACAAGGAGCTCAGTGACCTCCTGGACTTCAGCATGATGTTCCCGCTGCCTGTCACCAACGGGAAGGGC
CGGCCCGCCTCCCTGGCCGGGGCGCAGTTCGGAGGTTCAGGTCTTGAGGACCGGCCCAGCTCAGGCTCCTGGGGCAGCGGCGACCAGAGC
AGCTCCTCCTTTGACCCCAGCCGGACCTTCAGCGAGGGCACCCACTTCACTGAGTCGCACAGCAGCCTCTCTTCATCCACATTCCTGGGA
CCGGGACTCGGAGGCAAGAGCGGTGAGCGGGGCGCCTATGCCTCCTTCGGGAGAGACGCAGGCGTGGGCGGCCTGACTCAGGCTGGCTTC
CTGTCAGGCGAGCTGGCCCTCAACAGCCCCGGGCCCCTGTCCCCTTCGGGCATGAAGGGGACCTCCCAGTACTACCCCTCCTACTCCGGC
AGCTCCCGGCGGAGAGCGGCAGACGGCAGCCTAGACACGCAGCCCAAGAAGGTCCGGAAGGTCCCGCCGGGTCTTCCATCCTCGGTGTAC
CCACCCAGCTCAGGTGAGGACTACGGCAGGGATGCCACCGCCTACCCGTCCGCCAAGACCCCCAGCAGCACCTATCCCGCCCCCTTCTAC
GTGGCAGATGGCAGCCTGCACCCCTCAGCCGAGCTCTGGAGTCCCCCGGGCCAGGCGGGCTTCGGGCCCATGCTGGGTGGGGGCTCATCC
CCGCTGCCCCTCCCGCCCGGTAGCGGCCCGGTGGGCAGCAGTGGAAGCAGCAGCACGTTTGGTGGCCTGCACCAGCACGAGCGTATGGGC
TACCAGCTGCATGGAGCAGAGGTGAACGGTGGGCTCCCATCTGCATCCTCCTTCTCCTCAGCCCCCGGAGCCACGTACGGCGGCGTCTCC
AGCCACACGCCGCCTGTCAGCGGGGCCGACAGCCTCCTGGGCTCCCGAGGGACCACAGCTGGCAGCTCCGGGGATGCCCTCGGCAAAGCA
CTGGCCTCGATCTACTCCCCGGATCACTCAAGCAATAACTTCTCGTCCAGCCCTTCTACCCCCGTGGGCTCCCCCCAGGGCCTGGCAGGA
ACGTCACAGTGGCCTCGAGCAGGAGCCCCCGGTGCCTTATCGCCCAGCTACGACGGGGGTCTCCACGGCCTGCAGAGTAAGATAGAAGAC
CACCTGGACGAGGCCATCCACGTGCTCCGCAGCCACGCCGTGGGCACAGCCGGCGACATGCACACGCTGCTGCCTGGCCACGGGGCGCTG
GCCTCAGGTTTCACCGGCCCCATGTCACTGGGCGGGCGGCACGCAGGCCTGGTTGGAGGCAGCCACCCCGAGGACGGCCTCGCAGGCAGC
ACCAGCCTCATGCACAACCACGCGGCCCTCCCCAGCCAGCCAGGCACCCTCCCTGACCTGTCTCGGCCTCCCGACTCCTACAGTGGGCTA
GGGCGAGCAGGTGCCACGGCGGCCGCCAGCGAGATCAAGCGGGAGGAGAAGGAGGACGAGGAGAACACGTCAGCGGCTGACCACTCGGAG
GAGGAGAAGAAGGAGCTGAAGGCCCCCCGGGCCCGGACCAGCCCAGACGAGGACGAGGACGACCTTCTCCCCCCAGAGCAGAAGGCCGAG
CGGGAGAAGGAGCGCCGGGTGGCCAATAACGCCCGGGAGCGGCTGCGGGTCCGTGACATCAACGAGGCCTTTAAGGAGCTGGGGCGCATG
TGCCAACTGCACCTCAACAGCGAGAAGCCCCAGACCAAACTGCTCATCCTGCACCAGGCTGTCTCGGTCATCCTGAACTTGGAGCAGCAA
GTGCGAGGTGTGAGCCATGGGAAGAACGTGGATTGGATGGACTCTCAGGGGGAAGAGCAGCGCCTTTGGCAGAAGATGGCCAACAACCCT
GGAACTCCCTTTGAGGGTGTACTCATGCTTCGTTCCAGCATGGGAAAATGTAGGCTCTAAAGGGACCAGTTCTCCAAGAATGAGGCCACC
AGGACCTATCTGGCTGTCTTTTCCTACCATTAGCAAACTGAGACCTGGGATTCTGCTTCCCTGCCATTTCTCACCTGACAGTGTTGGGAC
ATGAGGGGAGAGATGTCAGTAGTATGAACATTTAGGGTCTTGCTGAGTGCCTAAAAAACATATATTTCCATCCAATCAAGGCCTTCTTGA
TTGGATGATAGAAAGTGTACTACTTGTCCTGTCAACAAGCAAATTGTGCAAAGGCTTATAGGGTTTATGCCATAAAAGAAATGGCACAAG
CCTCCATTTGCTAATTATAAGTTACTTTAGATTTCCTCAAATCCTTTGAAGAGAAAGAGGACCACTGAGAAGGTAGATCACTTGAAAAGT
CAGAAGAAAGGATACTGGCCAACTTTTACTCACCCTAGGAATCCACATGATCTCAAGAAGGCATGGTGGAGATGGTTGCTTGAGCAAGGG
GATTGTCCTGTTATTGCAGCAAACTTGTGGATTAACCAAGTAGTATTTCAAGATGGATTGACAGGGCTTTCTATGATTACTATAGAATTT
ATCATCTAAATCAGTTTACTTTTTAGAACAAAGAGAGCTAAATAACTACATCAGAACGATTGATGTTGATTAGAATTGACCTGGGAAAAT
TGGGATGTAGGGTCACCCTACTGATGACCTAAGAGAGCTCTGTTTTAAACATTTATTTTATAAAATGTTCTAAGCCATTAACTAAAAGGA
AATGAGATATAATGGTCAATTGATATACCTTTTCACATTGTGTTCACTGACGAGACTAGTTTAATGAAAAAGGAGGTACTCTACCTGCTA
TTTTACTTCTGTTCCTCTTCTGCCCTGTTATGGGAGAGAATCAAAGACTCCATCTGCTCTCTTCCCCCTTGTTTTCTCCTTCACTGAGTT
TTTCTTATCTCCTTTTGCAGTGGTTAACTATTGTCACAATAATGCTGAATGAAAAAACACACCAAATGTCAGTGGCTTAAAATGACCATC
CTTTTTCTCACAGTTATGAAGATTGGCTATGGCACCTCTGCTTCCTGCTATAGGCCTGAGGTTCTAGGGCTTCTTATGCCTCATCCTCTT
TAAGCCAAAGGGATAGCCAGAGCATCTTGATGGCAGAAGTGCAATAAGATGAGCCCCACTGCTCGGGTACATTTTCAGCCCCTGGTTGTG
TCATGTCTACTGATATCTCATTGGTCAAAGGAAGTCAGAGGGCCAAGATGAAGAGGCAGGGAAATATGCACTGCCCACAGTGAAGCCATG
ACAAGAGTGAGGATGCAGGAAGGCATGAAGAATTGGGGCCAACAGTTCAATCTACCATACCTTCTCTCACCTGGAATTCCAGATGCTTGA
GCTACGAAACTTAGATGCAAAGAAAGTTAAAGCTAGAAGGAACCTCAGGCCCAGTTGCTCATTTTGCAGATTCCAAATGTGAATTTCAGA
GAGCTGAGATAACTTGCCCAAGGCCATATAGAGGCTGTGACTAAATCTGGACTTAAATCCAGACTATCAATCTTAGGCCAGTGTTCTTTT
TTCAATATAGTCCTTGGCATAATGCTATGCTTATTAGGTAGATAAAAGGGCTTATGTCAAGAAATTTGGAGCAGAGTCTGATTACTTGAG
CATGAACATACCCGACCAAGGTATGTTCTGGAGTCATATTCTAGCCTCTGAGCTCATTTTTTCATGCGAGTTCATATAAAATCCTCGAAA
GTTTAGAAACTAGGTTTTAGTAGTAACGGAGCTAGAATCATCTTCGGGCTTATTCCTGCTAGTTGTTCCATATTTCTAGATTTCATCTTG
AATTTTGAAAACTGATTTAAGAATATATTTAGTATTATTATTAGTAAGGGAATACGCAATCCAGTTTCAATTTTATTCAGAAGTAGGTCA
CCTAATTCTAGAAAATGGTTATTAGTCTAGTGTCGCTTAGCAAGGTACTTAAAAGAAAATCTGCACATATCCTTGTGCTGCCCTTCTTAA

>89779_89779_2_TCF3-SYTL5_TCF3_chr19_1615283_ENST00000262965_SYTL5_chrX_37985840_ENST00000357972_length(amino acids)=654AA_BP=607
MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSS
STFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGL
PSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQ
HERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP
QGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPED
GLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSPDEDEDDLLPP
EQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRGVSHGKNVDWMDSQGEEQRLWQK

--------------------------------------------------------------
>89779_89779_3_TCF3-SYTL5_TCF3_chr19_1615283_ENST00000262965_SYTL5_chrX_37985840_ENST00000456733_length(transcript)=4399nt_BP=2167nt
TCCCGCCGCAGGAAGATGAGGCAGCGGCGGCGGCTGCGGGCGTAGCGGGCCGGAGCCGACGCGGCGGCGGGCACCGCGGGCACCGCGCAC
GCCGCTGCCCCAGGGGCGCCCCGGCCGGCCGCGCGCACGGGCCCCGCGGGACGGGCCACGCGGGGGTGGGAGGGGCCCGGGCCACGCGCG
CCGCCGCCGCCGCCCACGCGCGACCCTCGGGGGCCCGGCCGCGACGCACCTTTGTCCGGGGGGGGGCCCCCCCGCTTCATGCCGCCGCCC
CCCCCCACGCGCCGCGTGCCCGGCCGCGCCCAGCAGGGTTTCCAGGCCTGAGGTGCCCGCCCTGGCCCCAGGAGAATGAACCAGCCGCAG
AGGATGGCGCCTGTGGGCACAGACAAGGAGCTCAGTGACCTCCTGGACTTCAGCATGATGTTCCCGCTGCCTGTCACCAACGGGAAGGGC
CGGCCCGCCTCCCTGGCCGGGGCGCAGTTCGGAGGTTCAGGTCTTGAGGACCGGCCCAGCTCAGGCTCCTGGGGCAGCGGCGACCAGAGC
AGCTCCTCCTTTGACCCCAGCCGGACCTTCAGCGAGGGCACCCACTTCACTGAGTCGCACAGCAGCCTCTCTTCATCCACATTCCTGGGA
CCGGGACTCGGAGGCAAGAGCGGTGAGCGGGGCGCCTATGCCTCCTTCGGGAGAGACGCAGGCGTGGGCGGCCTGACTCAGGCTGGCTTC
CTGTCAGGCGAGCTGGCCCTCAACAGCCCCGGGCCCCTGTCCCCTTCGGGCATGAAGGGGACCTCCCAGTACTACCCCTCCTACTCCGGC
AGCTCCCGGCGGAGAGCGGCAGACGGCAGCCTAGACACGCAGCCCAAGAAGGTCCGGAAGGTCCCGCCGGGTCTTCCATCCTCGGTGTAC
CCACCCAGCTCAGGTGAGGACTACGGCAGGGATGCCACCGCCTACCCGTCCGCCAAGACCCCCAGCAGCACCTATCCCGCCCCCTTCTAC
GTGGCAGATGGCAGCCTGCACCCCTCAGCCGAGCTCTGGAGTCCCCCGGGCCAGGCGGGCTTCGGGCCCATGCTGGGTGGGGGCTCATCC
CCGCTGCCCCTCCCGCCCGGTAGCGGCCCGGTGGGCAGCAGTGGAAGCAGCAGCACGTTTGGTGGCCTGCACCAGCACGAGCGTATGGGC
TACCAGCTGCATGGAGCAGAGGTGAACGGTGGGCTCCCATCTGCATCCTCCTTCTCCTCAGCCCCCGGAGCCACGTACGGCGGCGTCTCC
AGCCACACGCCGCCTGTCAGCGGGGCCGACAGCCTCCTGGGCTCCCGAGGGACCACAGCTGGCAGCTCCGGGGATGCCCTCGGCAAAGCA
CTGGCCTCGATCTACTCCCCGGATCACTCAAGCAATAACTTCTCGTCCAGCCCTTCTACCCCCGTGGGCTCCCCCCAGGGCCTGGCAGGA
ACGTCACAGTGGCCTCGAGCAGGAGCCCCCGGTGCCTTATCGCCCAGCTACGACGGGGGTCTCCACGGCCTGCAGAGTAAGATAGAAGAC
CACCTGGACGAGGCCATCCACGTGCTCCGCAGCCACGCCGTGGGCACAGCCGGCGACATGCACACGCTGCTGCCTGGCCACGGGGCGCTG
GCCTCAGGTTTCACCGGCCCCATGTCACTGGGCGGGCGGCACGCAGGCCTGGTTGGAGGCAGCCACCCCGAGGACGGCCTCGCAGGCAGC
ACCAGCCTCATGCACAACCACGCGGCCCTCCCCAGCCAGCCAGGCACCCTCCCTGACCTGTCTCGGCCTCCCGACTCCTACAGTGGGCTA
GGGCGAGCAGGTGCCACGGCGGCCGCCAGCGAGATCAAGCGGGAGGAGAAGGAGGACGAGGAGAACACGTCAGCGGCTGACCACTCGGAG
GAGGAGAAGAAGGAGCTGAAGGCCCCCCGGGCCCGGACCAGCCCAGACGAGGACGAGGACGACCTTCTCCCCCCAGAGCAGAAGGCCGAG
CGGGAGAAGGAGCGCCGGGTGGCCAATAACGCCCGGGAGCGGCTGCGGGTCCGTGACATCAACGAGGCCTTTAAGGAGCTGGGGCGCATG
TGCCAACTGCACCTCAACAGCGAGAAGCCCCAGACCAAACTGCTCATCCTGCACCAGGCTGTCTCGGTCATCCTGAACTTGGAGCAGCAA
GTGCGAGGTGTGAGCCATGGGAAGAACGTGGATTGGATGGACTCTCAGGGGGAAGAGCAGCGCCTTTGGCAGAAGATGGCCAACAACCCT
GGAACTCCCTTTGAGGGTGTACTCATGCTTCGTTCCAGCATGGGAAAATGTAGGCTCTAAAGGGACCAGTTCTCCAAGAATGAGGCCACC
AGGACCTATCTGGCTGTCTTTTCCTACCATTAGCAAACTGAGACCTGGGATTCTGCTTCCCTGCCATTTCTCACCTGACAGTGTTGGGAC
ATGAGGGGAGAGATGTCAGTAGTATGAACATTTAGGGTCTTGCTGAGTGCCTAAAAAACATATATTTCCATCCAATCAAGGCCTTCTTGA
TTGGATGATAGAAAGTGTACTACTTGTCCTGTCAACAAGCAAATTGTGCAAAGGCTTATAGGGTTTATGCCATAAAAGAAATGGCACAAG
CCTCCATTTGCTAATTATAAGTTACTTTAGATTTCCTCAAATCCTTTGAAGAGAAAGAGGACCACTGAGAAGGTAGATCACTTGAAAAGT
CAGAAGAAAGGATACTGGCCAACTTTTACTCACCCTAGGAATCCACATGATCTCAAGAAGGCATGGTGGAGATGGTTGCTTGAGCAAGGG
GATTGTCCTGTTATTGCAGCAAACTTGTGGATTAACCAAGTAGTATTTCAAGATGGATTGACAGGGCTTTCTATGATTACTATAGAATTT
ATCATCTAAATCAGTTTACTTTTTAGAACAAAGAGAGCTAAATAACTACATCAGAACGATTGATGTTGATTAGAATTGACCTGGGAAAAT
TGGGATGTAGGGTCACCCTACTGATGACCTAAGAGAGCTCTGTTTTAAACATTTATTTTATAAAATGTTCTAAGCCATTAACTAAAAGGA
AATGAGATATAATGGTCAATTGATATACCTTTTCACATTGTGTTCACTGACGAGACTAGTTTAATGAAAAAGGAGGTACTCTACCTGCTA
TTTTACTTCTGTTCCTCTTCTGCCCTGTTATGGGAGAGAATCAAAGACTCCATCTGCTCTCTTCCCCCTTGTTTTCTCCTTCACTGAGTT
TTTCTTATCTCCTTTTGCAGTGGTTAACTATTGTCACAATAATGCTGAATGAAAAAACACACCAAATGTCAGTGGCTTAAAATGACCATC
CTTTTTCTCACAGTTATGAAGATTGGCTATGGCACCTCTGCTTCCTGCTATAGGCCTGAGGTTCTAGGGCTTCTTATGCCTCATCCTCTT
TAAGCCAAAGGGATAGCCAGAGCATCTTGATGGCAGAAGTGCAATAAGATGAGCCCCACTGCTCGGGTACATTTTCAGCCCCTGGTTGTG
TCATGTCTACTGATATCTCATTGGTCAAAGGAAGTCAGAGGGCCAAGATGAAGAGGCAGGGAAATATGCACTGCCCACAGTGAAGCCATG
ACAAGAGTGAGGATGCAGGAAGGCATGAAGAATTGGGGCCAACAGTTCAATCTACCATACCTTCTCTCACCTGGAATTCCAGATGCTTGA
GCTACGAAACTTAGATGCAAAGAAAGTTAAAGCTAGAAGGAACCTCAGGCCCAGTTGCTCATTTTGCAGATTCCAAATGTGAATTTCAGA
GAGCTGAGATAACTTGCCCAAGGCCATATAGAGGCTGTGACTAAATCTGGACTTAAATCCAGACTATCAATCTTAGGCCAGTGTTCTTTT
TTCAATATAGTCCTTGGCATAATGCTATGCTTATTAGGTAGATAAAAGGGCTTATGTCAAGAAATTTGGAGCAGAGTCTGATTACTTGAG
CATGAACATACCCGACCAAGGTATGTTCTGGAGTCATATTCTAGCCTCTGAGCTCATTTTTTCATGCGAGTTCATATAAAATCCTCGAAA
GTTTAGAAACTAGGTTTTAGTAGTAACGGAGCTAGAATCATCTTCGGGCTTATTCCTGCTAGTTGTTCCATATTTCTAGATTTCATCTTG
AATTTTGAAAACTGATTTAAGAATATATTTAGTATTATTATTAGTAAGGGAATACGCAATCCAGTTTCAATTTTATTCAGAAGTAGGTCA
CCTAATTCTAGAAAATGGTTATTAGTCTAGTGTCGCTTAGCAAGGTACTTAAAAGAAAATCTGCACATATCCTTGTGCTGCCCTTCTTAA

>89779_89779_3_TCF3-SYTL5_TCF3_chr19_1615283_ENST00000262965_SYTL5_chrX_37985840_ENST00000456733_length(amino acids)=654AA_BP=607
MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSS
STFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGL
PSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQ
HERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP
QGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPED
GLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSPDEDEDDLLPP
EQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRGVSHGKNVDWMDSQGEEQRLWQK

--------------------------------------------------------------
>89779_89779_4_TCF3-SYTL5_TCF3_chr19_1615284_ENST00000262965_SYTL5_chrX_37985841_ENST00000297875_length(transcript)=4396nt_BP=2167nt
TCCCGCCGCAGGAAGATGAGGCAGCGGCGGCGGCTGCGGGCGTAGCGGGCCGGAGCCGACGCGGCGGCGGGCACCGCGGGCACCGCGCAC
GCCGCTGCCCCAGGGGCGCCCCGGCCGGCCGCGCGCACGGGCCCCGCGGGACGGGCCACGCGGGGGTGGGAGGGGCCCGGGCCACGCGCG
CCGCCGCCGCCGCCCACGCGCGACCCTCGGGGGCCCGGCCGCGACGCACCTTTGTCCGGGGGGGGGCCCCCCCGCTTCATGCCGCCGCCC
CCCCCCACGCGCCGCGTGCCCGGCCGCGCCCAGCAGGGTTTCCAGGCCTGAGGTGCCCGCCCTGGCCCCAGGAGAATGAACCAGCCGCAG
AGGATGGCGCCTGTGGGCACAGACAAGGAGCTCAGTGACCTCCTGGACTTCAGCATGATGTTCCCGCTGCCTGTCACCAACGGGAAGGGC
CGGCCCGCCTCCCTGGCCGGGGCGCAGTTCGGAGGTTCAGGTCTTGAGGACCGGCCCAGCTCAGGCTCCTGGGGCAGCGGCGACCAGAGC
AGCTCCTCCTTTGACCCCAGCCGGACCTTCAGCGAGGGCACCCACTTCACTGAGTCGCACAGCAGCCTCTCTTCATCCACATTCCTGGGA
CCGGGACTCGGAGGCAAGAGCGGTGAGCGGGGCGCCTATGCCTCCTTCGGGAGAGACGCAGGCGTGGGCGGCCTGACTCAGGCTGGCTTC
CTGTCAGGCGAGCTGGCCCTCAACAGCCCCGGGCCCCTGTCCCCTTCGGGCATGAAGGGGACCTCCCAGTACTACCCCTCCTACTCCGGC
AGCTCCCGGCGGAGAGCGGCAGACGGCAGCCTAGACACGCAGCCCAAGAAGGTCCGGAAGGTCCCGCCGGGTCTTCCATCCTCGGTGTAC
CCACCCAGCTCAGGTGAGGACTACGGCAGGGATGCCACCGCCTACCCGTCCGCCAAGACCCCCAGCAGCACCTATCCCGCCCCCTTCTAC
GTGGCAGATGGCAGCCTGCACCCCTCAGCCGAGCTCTGGAGTCCCCCGGGCCAGGCGGGCTTCGGGCCCATGCTGGGTGGGGGCTCATCC
CCGCTGCCCCTCCCGCCCGGTAGCGGCCCGGTGGGCAGCAGTGGAAGCAGCAGCACGTTTGGTGGCCTGCACCAGCACGAGCGTATGGGC
TACCAGCTGCATGGAGCAGAGGTGAACGGTGGGCTCCCATCTGCATCCTCCTTCTCCTCAGCCCCCGGAGCCACGTACGGCGGCGTCTCC
AGCCACACGCCGCCTGTCAGCGGGGCCGACAGCCTCCTGGGCTCCCGAGGGACCACAGCTGGCAGCTCCGGGGATGCCCTCGGCAAAGCA
CTGGCCTCGATCTACTCCCCGGATCACTCAAGCAATAACTTCTCGTCCAGCCCTTCTACCCCCGTGGGCTCCCCCCAGGGCCTGGCAGGA
ACGTCACAGTGGCCTCGAGCAGGAGCCCCCGGTGCCTTATCGCCCAGCTACGACGGGGGTCTCCACGGCCTGCAGAGTAAGATAGAAGAC
CACCTGGACGAGGCCATCCACGTGCTCCGCAGCCACGCCGTGGGCACAGCCGGCGACATGCACACGCTGCTGCCTGGCCACGGGGCGCTG
GCCTCAGGTTTCACCGGCCCCATGTCACTGGGCGGGCGGCACGCAGGCCTGGTTGGAGGCAGCCACCCCGAGGACGGCCTCGCAGGCAGC
ACCAGCCTCATGCACAACCACGCGGCCCTCCCCAGCCAGCCAGGCACCCTCCCTGACCTGTCTCGGCCTCCCGACTCCTACAGTGGGCTA
GGGCGAGCAGGTGCCACGGCGGCCGCCAGCGAGATCAAGCGGGAGGAGAAGGAGGACGAGGAGAACACGTCAGCGGCTGACCACTCGGAG
GAGGAGAAGAAGGAGCTGAAGGCCCCCCGGGCCCGGACCAGCCCAGACGAGGACGAGGACGACCTTCTCCCCCCAGAGCAGAAGGCCGAG
CGGGAGAAGGAGCGCCGGGTGGCCAATAACGCCCGGGAGCGGCTGCGGGTCCGTGACATCAACGAGGCCTTTAAGGAGCTGGGGCGCATG
TGCCAACTGCACCTCAACAGCGAGAAGCCCCAGACCAAACTGCTCATCCTGCACCAGGCTGTCTCGGTCATCCTGAACTTGGAGCAGCAA
GTGCGAGGTGTGAGCCATGGGAAGAACGTGGATTGGATGGACTCTCAGGGGGAAGAGCAGCGCCTTTGGCAGAAGATGGCCAACAACCCT
GGAACTCCCTTTGAGGGTGTACTCATGCTTCGTTCCAGCATGGGAAAATGTAGGCTCTAAAGGGACCAGTTCTCCAAGAATGAGGCCACC
AGGACCTATCTGGCTGTCTTTTCCTACCATTAGCAAACTGAGACCTGGGATTCTGCTTCCCTGCCATTTCTCACCTGACAGTGTTGGGAC
ATGAGGGGAGAGATGTCAGTAGTATGAACATTTAGGGTCTTGCTGAGTGCCTAAAAAACATATATTTCCATCCAATCAAGGCCTTCTTGA
TTGGATGATAGAAAGTGTACTACTTGTCCTGTCAACAAGCAAATTGTGCAAAGGCTTATAGGGTTTATGCCATAAAAGAAATGGCACAAG
CCTCCATTTGCTAATTATAAGTTACTTTAGATTTCCTCAAATCCTTTGAAGAGAAAGAGGACCACTGAGAAGGTAGATCACTTGAAAAGT
CAGAAGAAAGGATACTGGCCAACTTTTACTCACCCTAGGAATCCACATGATCTCAAGAAGGCATGGTGGAGATGGTTGCTTGAGCAAGGG
GATTGTCCTGTTATTGCAGCAAACTTGTGGATTAACCAAGTAGTATTTCAAGATGGATTGACAGGGCTTTCTATGATTACTATAGAATTT
ATCATCTAAATCAGTTTACTTTTTAGAACAAAGAGAGCTAAATAACTACATCAGAACGATTGATGTTGATTAGAATTGACCTGGGAAAAT
TGGGATGTAGGGTCACCCTACTGATGACCTAAGAGAGCTCTGTTTTAAACATTTATTTTATAAAATGTTCTAAGCCATTAACTAAAAGGA
AATGAGATATAATGGTCAATTGATATACCTTTTCACATTGTGTTCACTGACGAGACTAGTTTAATGAAAAAGGAGGTACTCTACCTGCTA
TTTTACTTCTGTTCCTCTTCTGCCCTGTTATGGGAGAGAATCAAAGACTCCATCTGCTCTCTTCCCCCTTGTTTTCTCCTTCACTGAGTT
TTTCTTATCTCCTTTTGCAGTGGTTAACTATTGTCACAATAATGCTGAATGAAAAAACACACCAAATGTCAGTGGCTTAAAATGACCATC
CTTTTTCTCACAGTTATGAAGATTGGCTATGGCACCTCTGCTTCCTGCTATAGGCCTGAGGTTCTAGGGCTTCTTATGCCTCATCCTCTT
TAAGCCAAAGGGATAGCCAGAGCATCTTGATGGCAGAAGTGCAATAAGATGAGCCCCACTGCTCGGGTACATTTTCAGCCCCTGGTTGTG
TCATGTCTACTGATATCTCATTGGTCAAAGGAAGTCAGAGGGCCAAGATGAAGAGGCAGGGAAATATGCACTGCCCACAGTGAAGCCATG
ACAAGAGTGAGGATGCAGGAAGGCATGAAGAATTGGGGCCAACAGTTCAATCTACCATACCTTCTCTCACCTGGAATTCCAGATGCTTGA
GCTACGAAACTTAGATGCAAAGAAAGTTAAAGCTAGAAGGAACCTCAGGCCCAGTTGCTCATTTTGCAGATTCCAAATGTGAATTTCAGA
GAGCTGAGATAACTTGCCCAAGGCCATATAGAGGCTGTGACTAAATCTGGACTTAAATCCAGACTATCAATCTTAGGCCAGTGTTCTTTT
TTCAATATAGTCCTTGGCATAATGCTATGCTTATTAGGTAGATAAAAGGGCTTATGTCAAGAAATTTGGAGCAGAGTCTGATTACTTGAG
CATGAACATACCCGACCAAGGTATGTTCTGGAGTCATATTCTAGCCTCTGAGCTCATTTTTTCATGCGAGTTCATATAAAATCCTCGAAA
GTTTAGAAACTAGGTTTTAGTAGTAACGGAGCTAGAATCATCTTCGGGCTTATTCCTGCTAGTTGTTCCATATTTCTAGATTTCATCTTG
AATTTTGAAAACTGATTTAAGAATATATTTAGTATTATTATTAGTAAGGGAATACGCAATCCAGTTTCAATTTTATTCAGAAGTAGGTCA
CCTAATTCTAGAAAATGGTTATTAGTCTAGTGTCGCTTAGCAAGGTACTTAAAAGAAAATCTGCACATATCCTTGTGCTGCCCTTCTTAA

>89779_89779_4_TCF3-SYTL5_TCF3_chr19_1615284_ENST00000262965_SYTL5_chrX_37985841_ENST00000297875_length(amino acids)=654AA_BP=607
MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSS
STFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGL
PSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQ
HERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP
QGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPED
GLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSPDEDEDDLLPP
EQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRGVSHGKNVDWMDSQGEEQRLWQK

--------------------------------------------------------------
>89779_89779_5_TCF3-SYTL5_TCF3_chr19_1615284_ENST00000262965_SYTL5_chrX_37985841_ENST00000357972_length(transcript)=4399nt_BP=2167nt
TCCCGCCGCAGGAAGATGAGGCAGCGGCGGCGGCTGCGGGCGTAGCGGGCCGGAGCCGACGCGGCGGCGGGCACCGCGGGCACCGCGCAC
GCCGCTGCCCCAGGGGCGCCCCGGCCGGCCGCGCGCACGGGCCCCGCGGGACGGGCCACGCGGGGGTGGGAGGGGCCCGGGCCACGCGCG
CCGCCGCCGCCGCCCACGCGCGACCCTCGGGGGCCCGGCCGCGACGCACCTTTGTCCGGGGGGGGGCCCCCCCGCTTCATGCCGCCGCCC
CCCCCCACGCGCCGCGTGCCCGGCCGCGCCCAGCAGGGTTTCCAGGCCTGAGGTGCCCGCCCTGGCCCCAGGAGAATGAACCAGCCGCAG
AGGATGGCGCCTGTGGGCACAGACAAGGAGCTCAGTGACCTCCTGGACTTCAGCATGATGTTCCCGCTGCCTGTCACCAACGGGAAGGGC
CGGCCCGCCTCCCTGGCCGGGGCGCAGTTCGGAGGTTCAGGTCTTGAGGACCGGCCCAGCTCAGGCTCCTGGGGCAGCGGCGACCAGAGC
AGCTCCTCCTTTGACCCCAGCCGGACCTTCAGCGAGGGCACCCACTTCACTGAGTCGCACAGCAGCCTCTCTTCATCCACATTCCTGGGA
CCGGGACTCGGAGGCAAGAGCGGTGAGCGGGGCGCCTATGCCTCCTTCGGGAGAGACGCAGGCGTGGGCGGCCTGACTCAGGCTGGCTTC
CTGTCAGGCGAGCTGGCCCTCAACAGCCCCGGGCCCCTGTCCCCTTCGGGCATGAAGGGGACCTCCCAGTACTACCCCTCCTACTCCGGC
AGCTCCCGGCGGAGAGCGGCAGACGGCAGCCTAGACACGCAGCCCAAGAAGGTCCGGAAGGTCCCGCCGGGTCTTCCATCCTCGGTGTAC
CCACCCAGCTCAGGTGAGGACTACGGCAGGGATGCCACCGCCTACCCGTCCGCCAAGACCCCCAGCAGCACCTATCCCGCCCCCTTCTAC
GTGGCAGATGGCAGCCTGCACCCCTCAGCCGAGCTCTGGAGTCCCCCGGGCCAGGCGGGCTTCGGGCCCATGCTGGGTGGGGGCTCATCC
CCGCTGCCCCTCCCGCCCGGTAGCGGCCCGGTGGGCAGCAGTGGAAGCAGCAGCACGTTTGGTGGCCTGCACCAGCACGAGCGTATGGGC
TACCAGCTGCATGGAGCAGAGGTGAACGGTGGGCTCCCATCTGCATCCTCCTTCTCCTCAGCCCCCGGAGCCACGTACGGCGGCGTCTCC
AGCCACACGCCGCCTGTCAGCGGGGCCGACAGCCTCCTGGGCTCCCGAGGGACCACAGCTGGCAGCTCCGGGGATGCCCTCGGCAAAGCA
CTGGCCTCGATCTACTCCCCGGATCACTCAAGCAATAACTTCTCGTCCAGCCCTTCTACCCCCGTGGGCTCCCCCCAGGGCCTGGCAGGA
ACGTCACAGTGGCCTCGAGCAGGAGCCCCCGGTGCCTTATCGCCCAGCTACGACGGGGGTCTCCACGGCCTGCAGAGTAAGATAGAAGAC
CACCTGGACGAGGCCATCCACGTGCTCCGCAGCCACGCCGTGGGCACAGCCGGCGACATGCACACGCTGCTGCCTGGCCACGGGGCGCTG
GCCTCAGGTTTCACCGGCCCCATGTCACTGGGCGGGCGGCACGCAGGCCTGGTTGGAGGCAGCCACCCCGAGGACGGCCTCGCAGGCAGC
ACCAGCCTCATGCACAACCACGCGGCCCTCCCCAGCCAGCCAGGCACCCTCCCTGACCTGTCTCGGCCTCCCGACTCCTACAGTGGGCTA
GGGCGAGCAGGTGCCACGGCGGCCGCCAGCGAGATCAAGCGGGAGGAGAAGGAGGACGAGGAGAACACGTCAGCGGCTGACCACTCGGAG
GAGGAGAAGAAGGAGCTGAAGGCCCCCCGGGCCCGGACCAGCCCAGACGAGGACGAGGACGACCTTCTCCCCCCAGAGCAGAAGGCCGAG
CGGGAGAAGGAGCGCCGGGTGGCCAATAACGCCCGGGAGCGGCTGCGGGTCCGTGACATCAACGAGGCCTTTAAGGAGCTGGGGCGCATG
TGCCAACTGCACCTCAACAGCGAGAAGCCCCAGACCAAACTGCTCATCCTGCACCAGGCTGTCTCGGTCATCCTGAACTTGGAGCAGCAA
GTGCGAGGTGTGAGCCATGGGAAGAACGTGGATTGGATGGACTCTCAGGGGGAAGAGCAGCGCCTTTGGCAGAAGATGGCCAACAACCCT
GGAACTCCCTTTGAGGGTGTACTCATGCTTCGTTCCAGCATGGGAAAATGTAGGCTCTAAAGGGACCAGTTCTCCAAGAATGAGGCCACC
AGGACCTATCTGGCTGTCTTTTCCTACCATTAGCAAACTGAGACCTGGGATTCTGCTTCCCTGCCATTTCTCACCTGACAGTGTTGGGAC
ATGAGGGGAGAGATGTCAGTAGTATGAACATTTAGGGTCTTGCTGAGTGCCTAAAAAACATATATTTCCATCCAATCAAGGCCTTCTTGA
TTGGATGATAGAAAGTGTACTACTTGTCCTGTCAACAAGCAAATTGTGCAAAGGCTTATAGGGTTTATGCCATAAAAGAAATGGCACAAG
CCTCCATTTGCTAATTATAAGTTACTTTAGATTTCCTCAAATCCTTTGAAGAGAAAGAGGACCACTGAGAAGGTAGATCACTTGAAAAGT
CAGAAGAAAGGATACTGGCCAACTTTTACTCACCCTAGGAATCCACATGATCTCAAGAAGGCATGGTGGAGATGGTTGCTTGAGCAAGGG
GATTGTCCTGTTATTGCAGCAAACTTGTGGATTAACCAAGTAGTATTTCAAGATGGATTGACAGGGCTTTCTATGATTACTATAGAATTT
ATCATCTAAATCAGTTTACTTTTTAGAACAAAGAGAGCTAAATAACTACATCAGAACGATTGATGTTGATTAGAATTGACCTGGGAAAAT
TGGGATGTAGGGTCACCCTACTGATGACCTAAGAGAGCTCTGTTTTAAACATTTATTTTATAAAATGTTCTAAGCCATTAACTAAAAGGA
AATGAGATATAATGGTCAATTGATATACCTTTTCACATTGTGTTCACTGACGAGACTAGTTTAATGAAAAAGGAGGTACTCTACCTGCTA
TTTTACTTCTGTTCCTCTTCTGCCCTGTTATGGGAGAGAATCAAAGACTCCATCTGCTCTCTTCCCCCTTGTTTTCTCCTTCACTGAGTT
TTTCTTATCTCCTTTTGCAGTGGTTAACTATTGTCACAATAATGCTGAATGAAAAAACACACCAAATGTCAGTGGCTTAAAATGACCATC
CTTTTTCTCACAGTTATGAAGATTGGCTATGGCACCTCTGCTTCCTGCTATAGGCCTGAGGTTCTAGGGCTTCTTATGCCTCATCCTCTT
TAAGCCAAAGGGATAGCCAGAGCATCTTGATGGCAGAAGTGCAATAAGATGAGCCCCACTGCTCGGGTACATTTTCAGCCCCTGGTTGTG
TCATGTCTACTGATATCTCATTGGTCAAAGGAAGTCAGAGGGCCAAGATGAAGAGGCAGGGAAATATGCACTGCCCACAGTGAAGCCATG
ACAAGAGTGAGGATGCAGGAAGGCATGAAGAATTGGGGCCAACAGTTCAATCTACCATACCTTCTCTCACCTGGAATTCCAGATGCTTGA
GCTACGAAACTTAGATGCAAAGAAAGTTAAAGCTAGAAGGAACCTCAGGCCCAGTTGCTCATTTTGCAGATTCCAAATGTGAATTTCAGA
GAGCTGAGATAACTTGCCCAAGGCCATATAGAGGCTGTGACTAAATCTGGACTTAAATCCAGACTATCAATCTTAGGCCAGTGTTCTTTT
TTCAATATAGTCCTTGGCATAATGCTATGCTTATTAGGTAGATAAAAGGGCTTATGTCAAGAAATTTGGAGCAGAGTCTGATTACTTGAG
CATGAACATACCCGACCAAGGTATGTTCTGGAGTCATATTCTAGCCTCTGAGCTCATTTTTTCATGCGAGTTCATATAAAATCCTCGAAA
GTTTAGAAACTAGGTTTTAGTAGTAACGGAGCTAGAATCATCTTCGGGCTTATTCCTGCTAGTTGTTCCATATTTCTAGATTTCATCTTG
AATTTTGAAAACTGATTTAAGAATATATTTAGTATTATTATTAGTAAGGGAATACGCAATCCAGTTTCAATTTTATTCAGAAGTAGGTCA
CCTAATTCTAGAAAATGGTTATTAGTCTAGTGTCGCTTAGCAAGGTACTTAAAAGAAAATCTGCACATATCCTTGTGCTGCCCTTCTTAA

>89779_89779_5_TCF3-SYTL5_TCF3_chr19_1615284_ENST00000262965_SYTL5_chrX_37985841_ENST00000357972_length(amino acids)=654AA_BP=607
MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSS
STFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGL
PSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQ
HERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP
QGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPED
GLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSPDEDEDDLLPP
EQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRGVSHGKNVDWMDSQGEEQRLWQK

--------------------------------------------------------------
>89779_89779_6_TCF3-SYTL5_TCF3_chr19_1615284_ENST00000262965_SYTL5_chrX_37985841_ENST00000456733_length(transcript)=4399nt_BP=2167nt
TCCCGCCGCAGGAAGATGAGGCAGCGGCGGCGGCTGCGGGCGTAGCGGGCCGGAGCCGACGCGGCGGCGGGCACCGCGGGCACCGCGCAC
GCCGCTGCCCCAGGGGCGCCCCGGCCGGCCGCGCGCACGGGCCCCGCGGGACGGGCCACGCGGGGGTGGGAGGGGCCCGGGCCACGCGCG
CCGCCGCCGCCGCCCACGCGCGACCCTCGGGGGCCCGGCCGCGACGCACCTTTGTCCGGGGGGGGGCCCCCCCGCTTCATGCCGCCGCCC
CCCCCCACGCGCCGCGTGCCCGGCCGCGCCCAGCAGGGTTTCCAGGCCTGAGGTGCCCGCCCTGGCCCCAGGAGAATGAACCAGCCGCAG
AGGATGGCGCCTGTGGGCACAGACAAGGAGCTCAGTGACCTCCTGGACTTCAGCATGATGTTCCCGCTGCCTGTCACCAACGGGAAGGGC
CGGCCCGCCTCCCTGGCCGGGGCGCAGTTCGGAGGTTCAGGTCTTGAGGACCGGCCCAGCTCAGGCTCCTGGGGCAGCGGCGACCAGAGC
AGCTCCTCCTTTGACCCCAGCCGGACCTTCAGCGAGGGCACCCACTTCACTGAGTCGCACAGCAGCCTCTCTTCATCCACATTCCTGGGA
CCGGGACTCGGAGGCAAGAGCGGTGAGCGGGGCGCCTATGCCTCCTTCGGGAGAGACGCAGGCGTGGGCGGCCTGACTCAGGCTGGCTTC
CTGTCAGGCGAGCTGGCCCTCAACAGCCCCGGGCCCCTGTCCCCTTCGGGCATGAAGGGGACCTCCCAGTACTACCCCTCCTACTCCGGC
AGCTCCCGGCGGAGAGCGGCAGACGGCAGCCTAGACACGCAGCCCAAGAAGGTCCGGAAGGTCCCGCCGGGTCTTCCATCCTCGGTGTAC
CCACCCAGCTCAGGTGAGGACTACGGCAGGGATGCCACCGCCTACCCGTCCGCCAAGACCCCCAGCAGCACCTATCCCGCCCCCTTCTAC
GTGGCAGATGGCAGCCTGCACCCCTCAGCCGAGCTCTGGAGTCCCCCGGGCCAGGCGGGCTTCGGGCCCATGCTGGGTGGGGGCTCATCC
CCGCTGCCCCTCCCGCCCGGTAGCGGCCCGGTGGGCAGCAGTGGAAGCAGCAGCACGTTTGGTGGCCTGCACCAGCACGAGCGTATGGGC
TACCAGCTGCATGGAGCAGAGGTGAACGGTGGGCTCCCATCTGCATCCTCCTTCTCCTCAGCCCCCGGAGCCACGTACGGCGGCGTCTCC
AGCCACACGCCGCCTGTCAGCGGGGCCGACAGCCTCCTGGGCTCCCGAGGGACCACAGCTGGCAGCTCCGGGGATGCCCTCGGCAAAGCA
CTGGCCTCGATCTACTCCCCGGATCACTCAAGCAATAACTTCTCGTCCAGCCCTTCTACCCCCGTGGGCTCCCCCCAGGGCCTGGCAGGA
ACGTCACAGTGGCCTCGAGCAGGAGCCCCCGGTGCCTTATCGCCCAGCTACGACGGGGGTCTCCACGGCCTGCAGAGTAAGATAGAAGAC
CACCTGGACGAGGCCATCCACGTGCTCCGCAGCCACGCCGTGGGCACAGCCGGCGACATGCACACGCTGCTGCCTGGCCACGGGGCGCTG
GCCTCAGGTTTCACCGGCCCCATGTCACTGGGCGGGCGGCACGCAGGCCTGGTTGGAGGCAGCCACCCCGAGGACGGCCTCGCAGGCAGC
ACCAGCCTCATGCACAACCACGCGGCCCTCCCCAGCCAGCCAGGCACCCTCCCTGACCTGTCTCGGCCTCCCGACTCCTACAGTGGGCTA
GGGCGAGCAGGTGCCACGGCGGCCGCCAGCGAGATCAAGCGGGAGGAGAAGGAGGACGAGGAGAACACGTCAGCGGCTGACCACTCGGAG
GAGGAGAAGAAGGAGCTGAAGGCCCCCCGGGCCCGGACCAGCCCAGACGAGGACGAGGACGACCTTCTCCCCCCAGAGCAGAAGGCCGAG
CGGGAGAAGGAGCGCCGGGTGGCCAATAACGCCCGGGAGCGGCTGCGGGTCCGTGACATCAACGAGGCCTTTAAGGAGCTGGGGCGCATG
TGCCAACTGCACCTCAACAGCGAGAAGCCCCAGACCAAACTGCTCATCCTGCACCAGGCTGTCTCGGTCATCCTGAACTTGGAGCAGCAA
GTGCGAGGTGTGAGCCATGGGAAGAACGTGGATTGGATGGACTCTCAGGGGGAAGAGCAGCGCCTTTGGCAGAAGATGGCCAACAACCCT
GGAACTCCCTTTGAGGGTGTACTCATGCTTCGTTCCAGCATGGGAAAATGTAGGCTCTAAAGGGACCAGTTCTCCAAGAATGAGGCCACC
AGGACCTATCTGGCTGTCTTTTCCTACCATTAGCAAACTGAGACCTGGGATTCTGCTTCCCTGCCATTTCTCACCTGACAGTGTTGGGAC
ATGAGGGGAGAGATGTCAGTAGTATGAACATTTAGGGTCTTGCTGAGTGCCTAAAAAACATATATTTCCATCCAATCAAGGCCTTCTTGA
TTGGATGATAGAAAGTGTACTACTTGTCCTGTCAACAAGCAAATTGTGCAAAGGCTTATAGGGTTTATGCCATAAAAGAAATGGCACAAG
CCTCCATTTGCTAATTATAAGTTACTTTAGATTTCCTCAAATCCTTTGAAGAGAAAGAGGACCACTGAGAAGGTAGATCACTTGAAAAGT
CAGAAGAAAGGATACTGGCCAACTTTTACTCACCCTAGGAATCCACATGATCTCAAGAAGGCATGGTGGAGATGGTTGCTTGAGCAAGGG
GATTGTCCTGTTATTGCAGCAAACTTGTGGATTAACCAAGTAGTATTTCAAGATGGATTGACAGGGCTTTCTATGATTACTATAGAATTT
ATCATCTAAATCAGTTTACTTTTTAGAACAAAGAGAGCTAAATAACTACATCAGAACGATTGATGTTGATTAGAATTGACCTGGGAAAAT
TGGGATGTAGGGTCACCCTACTGATGACCTAAGAGAGCTCTGTTTTAAACATTTATTTTATAAAATGTTCTAAGCCATTAACTAAAAGGA
AATGAGATATAATGGTCAATTGATATACCTTTTCACATTGTGTTCACTGACGAGACTAGTTTAATGAAAAAGGAGGTACTCTACCTGCTA
TTTTACTTCTGTTCCTCTTCTGCCCTGTTATGGGAGAGAATCAAAGACTCCATCTGCTCTCTTCCCCCTTGTTTTCTCCTTCACTGAGTT
TTTCTTATCTCCTTTTGCAGTGGTTAACTATTGTCACAATAATGCTGAATGAAAAAACACACCAAATGTCAGTGGCTTAAAATGACCATC
CTTTTTCTCACAGTTATGAAGATTGGCTATGGCACCTCTGCTTCCTGCTATAGGCCTGAGGTTCTAGGGCTTCTTATGCCTCATCCTCTT
TAAGCCAAAGGGATAGCCAGAGCATCTTGATGGCAGAAGTGCAATAAGATGAGCCCCACTGCTCGGGTACATTTTCAGCCCCTGGTTGTG
TCATGTCTACTGATATCTCATTGGTCAAAGGAAGTCAGAGGGCCAAGATGAAGAGGCAGGGAAATATGCACTGCCCACAGTGAAGCCATG
ACAAGAGTGAGGATGCAGGAAGGCATGAAGAATTGGGGCCAACAGTTCAATCTACCATACCTTCTCTCACCTGGAATTCCAGATGCTTGA
GCTACGAAACTTAGATGCAAAGAAAGTTAAAGCTAGAAGGAACCTCAGGCCCAGTTGCTCATTTTGCAGATTCCAAATGTGAATTTCAGA
GAGCTGAGATAACTTGCCCAAGGCCATATAGAGGCTGTGACTAAATCTGGACTTAAATCCAGACTATCAATCTTAGGCCAGTGTTCTTTT
TTCAATATAGTCCTTGGCATAATGCTATGCTTATTAGGTAGATAAAAGGGCTTATGTCAAGAAATTTGGAGCAGAGTCTGATTACTTGAG
CATGAACATACCCGACCAAGGTATGTTCTGGAGTCATATTCTAGCCTCTGAGCTCATTTTTTCATGCGAGTTCATATAAAATCCTCGAAA
GTTTAGAAACTAGGTTTTAGTAGTAACGGAGCTAGAATCATCTTCGGGCTTATTCCTGCTAGTTGTTCCATATTTCTAGATTTCATCTTG
AATTTTGAAAACTGATTTAAGAATATATTTAGTATTATTATTAGTAAGGGAATACGCAATCCAGTTTCAATTTTATTCAGAAGTAGGTCA
CCTAATTCTAGAAAATGGTTATTAGTCTAGTGTCGCTTAGCAAGGTACTTAAAAGAAAATCTGCACATATCCTTGTGCTGCCCTTCTTAA

>89779_89779_6_TCF3-SYTL5_TCF3_chr19_1615284_ENST00000262965_SYTL5_chrX_37985841_ENST00000456733_length(amino acids)=654AA_BP=607
MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSS
STFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGL
PSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQ
HERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP
QGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPED
GLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSPDEDEDDLLPP
EQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRGVSHGKNVDWMDSQGEEQRLWQK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TCF3-SYTL5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TCF3-SYTL5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TCF3-SYTL5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource