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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:TCP11L1-SYT9 (FusionGDB2 ID:89874)

Fusion Gene Summary for TCP11L1-SYT9

Fusion gene summary

Fusion gene information	Fusion gene name: TCP11L1-SYT9
	Fusion gene ID: 89874
		Hgene	Tgene
	Gene symbol	TCP11L1	SYT9
	Gene ID	55346	143425
	Gene name	t-complex 11 like 1	synaptotagmin 9
	Synonyms	dJ85M6.3	-
	Cytomap	11p13	11p15.4
	Type of gene	protein-coding	protein-coding
	Description	T-complex protein 11-like protein 1t-complex 11, testis-specific-like 1	synaptotagmin-9synaptotagmin IXsytIX
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000334274, ENST00000432887, ENST00000324357, ENST00000531632, ENST00000530171,	ENST00000318881, ENST00000396716,
Fusion gene scores	* DoF score	2 X 2 X 2=8	3 X 3 X 3=27
	# samples	2	3
	** MAII score	log2(2/8*10)=1.32192809488736	log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: TCP11L1 [Title/Abstract] AND SYT9 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	TCP11L1(33094199)-SYT9(7324270), # samples:3
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across TCP11L1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across SYT9 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-S3-AA17-01A	TCP11L1	chr11	33094199	-	SYT9	chr11	7324270	+
ChimerDB4	BRCA	TCGA-S3-AA17-01A	TCP11L1	chr11	33094199	+	SYT9	chr11	7324270	+

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Fusion Gene ORF analysis for TCP11L1-SYT9

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
Frame-shift	ENST00000334274	ENST00000318881	TCP11L1	chr11	33094199	+	SYT9	chr11	7324270	+
Frame-shift	ENST00000334274	ENST00000396716	TCP11L1	chr11	33094199	+	SYT9	chr11	7324270	+
Frame-shift	ENST00000432887	ENST00000318881	TCP11L1	chr11	33094199	+	SYT9	chr11	7324270	+
Frame-shift	ENST00000432887	ENST00000396716	TCP11L1	chr11	33094199	+	SYT9	chr11	7324270	+
In-frame	ENST00000324357	ENST00000318881	TCP11L1	chr11	33094199	+	SYT9	chr11	7324270	+
In-frame	ENST00000324357	ENST00000396716	TCP11L1	chr11	33094199	+	SYT9	chr11	7324270	+
In-frame	ENST00000531632	ENST00000318881	TCP11L1	chr11	33094199	+	SYT9	chr11	7324270	+
In-frame	ENST00000531632	ENST00000396716	TCP11L1	chr11	33094199	+	SYT9	chr11	7324270	+
intron-3CDS	ENST00000530171	ENST00000318881	TCP11L1	chr11	33094199	+	SYT9	chr11	7324270	+
intron-3CDS	ENST00000530171	ENST00000396716	TCP11L1	chr11	33094199	+	SYT9	chr11	7324270	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

ENST00000531632

TCP11L1

chr11

33094199

ENST00000318881

SYT9

chr11

7324270

5291

1718

1687

3048

453

ENST00000531632

TCP11L1

chr11

33094199

ENST00000396716

SYT9

chr11

7324270

2629

1718

190

1545

451

ENST00000324357

TCP11L1

chr11

33094199

ENST00000318881

SYT9

chr11

7324270

4429

856

2186

727

ENST00000324357

TCP11L1

chr11

33094199

ENST00000396716

SYT9

chr11

7324270

1767

856

1766

587

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000531632	ENST00000318881	TCP11L1	chr11	33094199	+	SYT9	chr11	7324270	+	0.003361813	0.9966382
ENST00000531632	ENST00000396716	TCP11L1	chr11	33094199	+	SYT9	chr11	7324270	+	0.003051465	0.99694854
ENST00000324357	ENST00000318881	TCP11L1	chr11	33094199	+	SYT9	chr11	7324270	+	0.006811647	0.9931884
ENST00000324357	ENST00000396716	TCP11L1	chr11	33094199	+	SYT9	chr11	7324270	+	0.005976392	0.9940236

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Fusion Genomic Features for TCP11L1-SYT9

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
TCP11L1	chr11	33094199	+	SYT9	chr11	7324269	+	9.86E-07	0.99999905
TCP11L1	chr11	33094199	+	SYT9	chr11	7324269	+	9.86E-07	0.99999905

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TCP11L1-SYT9

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:33094199/chr11:7324270)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

SYT9

chr11:33094199

chr11:7324270

ENST00000318881

220_341

492.0

Domain

C2 1

Tgene

SYT9

chr11:33094199

chr11:7324270

ENST00000318881

352_485

492.0

Domain

C2 2

Tgene

SYT9

chr11:33094199

chr11:7324270

ENST00000318881

74_491

492.0

Topological domain

Cytoplasmic

Tgene

SYT9

chr11:33094199

chr11:7324270

ENST00000318881

53_73

492.0

Transmembrane

Helical

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

SYT9

chr11:33094199

chr11:7324270

ENST00000318881

9_31

492.0

Region

Cysteine motif

Tgene

SYT9

chr11:33094199

chr11:7324270

ENST00000318881

1_52

492.0

Topological domain

Vesicular

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Fusion Gene Sequence for TCP11L1-SYT9

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>89874_89874_1_TCP11L1-SYT9_TCP11L1_chr11_33094199_ENST00000324357_SYT9_chr11_7324270_ENST00000318881_length(transcript)=4429nt_BP=856nt
GTGTTGGACCTAATGAAAGTGGACATGGCCAACTTTGCTATCAGTAGCATCAGGCCTCATCTCATGCAGCAGTCAGTTGAATACGAAAGG
AAGAAGTTTCAAGAGATTTTGGAGAGGCAACCAAATTCCCTGGACTTTGTCACCCAGTGGCTGGAAGAAGCCTCAGAGGACCTTATGACT
CAGAAGTATAAACACGCCCTGCCAGTGGGGGGAATGGCTGCTGGCTCTGGGGACATGCCCAGGCTGAGCCCTGTTGCTGTCCAGAATTAC
GCTTACCTGAAGCTTCTGAAGTGGGACCACCTCCAGAGGCCGTTCCCCGAAACAGTTTTAATGGACCAGTCTCGCTTCCACGAGCTCCAG
TTGCAGCTGGAACAACTGACCATCCTGGGGGCTGTGTTGCTGGTCACCTTCAGCATGGCAGCGCCAGGAATTTCCAGCCAGGCCGACTTT
GCTGAGAAACTCAAGATGATTGTGAAGATTTTGCTAACAGATATGCACCTGCCCTCCTTCCATCTGAAGGACGTCCTCACTACCATCGGG
GAGAAGGTGTGCCTGGAGGTGAGCAGCTGCCTCTCCCTGTGTGGGTCCTCTCCCTTCACCACGGACAAGGAGACCGTGCTCAAGGGCCAG
ATCCAGGCCGTGGCCAGTCCCGATGACCCCATTCGCAGGATCATGGAATCTCGAATCCTGACCTTCTTAGAAACCTACCTTGCCTCGGGT
CATCAGAAGCCATTGCCCACAGTCCCTGGGGGACTCAGTCCAGTTCAGAGAGAGCTGGAGGAAGTTGCTATTAAATTTGCTCGCCTGGTC
AACTATAACAAGATGGTCTTCTGTCCCTACTACGATGCAATCCTGAATATCTCAGTGAGCCTGCTGACCCTTGTGGTCACTGCCTGTGGT
CTCGCTCTCTTTGGCGTGTCTCTCTTCGTATCTTGGAAACTCTGCTGGGTTCCGTGGCGAGAACGAGGCCTGCCCTCTGGTAGCAAAGAC
AACAACCAGGAGCCCCTTAACTACATGGACACAGAGACCAATGAGCAGGAGAACAGTGAGGACTTCCTAGATCCTCCCACGCCCTGCCCT
GACTCCTCCATGAAGATCAGCCACACCTCCCCTGACATTCCCCTCTCCACCCAGACGGGGATCCAGGAGAACTGTGCCCATGGCGTCCGC
GTGCAGCGCCAAGTCACAGAGCCAACCTCGTCGGCCCGGCATAATTCAATCCGAAGACAACTCAACTTGTCAAACCCGGACTTCAATATC
CAGCAGCTTCAAAAACAGGAACAGTTGACTGGAATTGGTAGAATTAAACCAGAGTTATATAAGCAGAGGTCATTGGATAATGATGACGGG
AGACGGAGTAACAGCAAGGCTTGTGGGAAACTGAACTTCATTTTAAAATATGACTGTGACTTAGAGCAGCTCATAGTGAAGATTCACAAA
GCTGTCAATTTGCCCGCCAAGGACTTTTCTGGGACTTCAGATCCTTATGTCAAGATCTATTTGCTTCCTGATCGGAAAACAAAACACCAG
ACTAAAGTTCACAGAAAGACCCTGAACCCTGTGTTTGATGAAGTGTTTTTATTTCCGGTTCCCTACAATGACCTTGAAGCACGGAAGCTT
CACTTCTCTGTGTACGACTTTGACAGGTTCTCTCGTCATGACTTAATCGGCCAAGTGGTGGTGGATCACTTCCTAGACTTGGCTGATTTC
CCCAGGGAGTGCATCCTTTGGAAGGATATCGAATATGTCACCAATGACAACGTGGATCTGGGAGAGCTGATGTTTTCCCTGTGCTATCTT
CCAACGGCTGGCAGGCTGACCATTACCATTATAAAAGCAAGGAATTTAAAGGCAATGGACATAACAGGAGCATCAGATCCCTATGTGAAA
GTCTCGCTGATGTGTGATGGCAGACGACTGAAGAAGAGGAAAACATCCACCAAGAGGAACACCTTGAATCCTGTTTACAACGAAGCCATA
GTCTTTGATGTCCCTCCCGAGAACATTGACCAAATCCACTTGTCCATAGCAGTCATGGACTATGACCGTGTAGGTCACAATGAGATCATC
GGCGTGTGTCAAGTAGGCAACGAGGCTGAGAGGCTGGGCAGAGACCACTGGAGTGAAATGTTGTCATATCCTCGGAAGCCCATTGCACAC
TGGCATTCCCTGGTGGAGAAACGATGACCATGGGTAAGAGGACTGCTTGTGCCAAGGACAAAATAGGACAACCATCTCACAAAGATCTTA
AGTAACTTTTTCCATCCAGCAACATCCAGACGATTTCAGTGACCAAATGCTCAGCTGTAACCACAGCACTAACTGGCCTTCTTTCCAGAT
TGGGTTTGGTGAACCTGAATGGTCCAGCCACCTTCTGCAGGTGGCCCAAGGTGATGTGCTGCAGGGAAGCATGTCTCTCATGCCAAGAAC
CAAGATCGGACTATGAACAAAAACAAATGATAGATATAGTGACAGTACCAAGAGTACCAGGACTCAATGTTTCATATGAAGCCCTTGGTG
ATGAGGACATAGCATCTGCCCTGGAAATCGTTATTCCAACATAATATTATTTTCTAGAATGCCCTGGAAGGACAGAATATTTAAAAATAT
ATCCAGGTGCTAAATAGGCAGCAGATCTCAATTCACACATGACTACCTTTGAGCTAATGACTGTCTCCAGAAAATAACTGTGCCCCAAGA
AGTGCTCCAGATTTGCAAGGAATAGCCCCAAGAGAATACCAAGACAAGCAGGCTGTTCCCTGGAAAAAATCTAATGCAAGGAGGGCTAGT
TCACAGCAAATTCACTGCCTCCTCCCATGCACGTGGTAGAGAGTACCAGTATCAACATGGCCCTGTTTTCTGCTAAAACCAGATTTTGAG
GAATCAGAGACCCCCAACACTACTCACTCAGTAGCTAGCAGCCCCTTCCTTTCAACTGGGAGTGTTATTAGAATGAAAAGTAATTAGTTA
GAAGGGCATACATCTCAGTGGCATGAGCATTGTGGAATATCCTTTCCTAGGCACATTCGTCCACTAAGGGAACAGCCTCAGAAACTGGTA
CAGCAATGGGTGAGATGAGATCATGGAGAGAGAACACAGCCATCCCCTATAGAAAGGCACAGCTTTTGGGCTTCTCTGGCCTGAATGCCT
TCTGGGGTATTTCCATATGCAACAGCCCAGAGTCATAGCCTTGGGCAACCACACATAGAGGTTTCCTTCTCACTTCAGACACATACATCA
CTTTCACACCACTTGGGGATGGAAATACCTACAAGAGTGAAGGTCAAGGGCCCTCCCCAGGCATCTCATTCATTACTCAGCTTCCTTCCT
GACCAAGTCTGCCAACCAATGGCCAGCTATGCGCCTCATCCTCATTGCTTCTGCCTCCACGTAAATGAAACCAAAGGCCTCAGCATATCC
TGGGAGGACTGGGGGCTGTTACCTAATGGTCCTCTCTGTCCCATTATAGGTGCAAGGCACCCCATCCACACATTTGCACCACTACTCCAA
GATAGTATTTTTCTTTTCACACAATCTCTTTACAGCAGAATCCAGAGTTGGATTGTAGTTTACCTTCCTGGAAAGCTCATTATCTCTGTT
TGAATTAACATTTCAGCATGGAACTAACTGGGCGGAGGAAGGATCGTTATACGTCTTCAGAAAGTTCTCATTGCCCCAGCTGCCTAGTAC
TATACAAGAAGCTCTACTTTGATGGCAGATCTAAGAAGGCTATAGGCCTTTGTTTGTAGGAAGCAGTGTCATTACATTCAAGCTTCACTT
CTCTGATTGGCTTCCAACCACTGGGATTCAAAGAGAATCCAAGGTTCTGCCTATGTCTGATGACATAAGGAAAACTTGGCTTCCTCTGCT
CAAGGTTCCCCTCTGCTCATCCCTCCTCATTCAGACATCCTCCACCATACCAGTGTTTAGAAGCAAAACATGAAGGGCTAGCGCCACCAG
GATAGTTAGCAGAAATATTGTCTGTAAAGCTAGGCAGATGAGCCCAGAAGAATGGTCCCAGAGAAAGCAGACTGGCTCCAATAGATATCA
GGCAGCAATCCCAATAAATTCTGACATGTCCTTGGCAATGGAAGCCTGGGTTGGAGATCCTGAGGCAGCTGTGCCTACTGTTCCCCACCT
CAGAAGCTTCCTGCCCAGAGAGCCAGCAGCCTTGGGATACTAATGAGGATGCAACTGGCTTATTGGTATGAAATAGAAGGTGGCTTTGTA
GGGGCAAGCAGGCAAAGAGTACTATCCACATGGCAGGCAGGTGGCTTTGTGTCTGGAAAGCTTTGCCTAGCCAGTACAGCTGTGAGCAGA
GGCTGGTTATAAATTTGAACTCCCTCAGCCCATTTGCAACTCTGCCTCTGTTCTCTTGCATTCTGTTTGGTTGCCCTTTAGTTTCCTAGT

>89874_89874_1_TCP11L1-SYT9_TCP11L1_chr11_33094199_ENST00000324357_SYT9_chr11_7324270_ENST00000318881_length(amino acids)=727AA_BP=285
MDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEILERQPNSLDFVTQWLEEASEDLMTQKYKHALPVGGMAAGSGDMPRLSPVAVQNYA
YLKLLKWDHLQRPFPETVLMDQSRFHELQLQLEQLTILGAVLLVTFSMAAPGISSQADFAEKLKMIVKILLTDMHLPSFHLKDVLTTIGE
KVCLEVSSCLSLCGSSPFTTDKETVLKGQIQAVASPDDPIRRIMESRILTFLETYLASGHQKPLPTVPGGLSPVQRELEEVAIKFARLVN
YNKMVFCPYYDAILNISVSLLTLVVTACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPTPCPD
SSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGR
RSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLH
FSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKV
SLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHW

--------------------------------------------------------------
>89874_89874_2_TCP11L1-SYT9_TCP11L1_chr11_33094199_ENST00000324357_SYT9_chr11_7324270_ENST00000396716_length(transcript)=1767nt_BP=856nt
GTGTTGGACCTAATGAAAGTGGACATGGCCAACTTTGCTATCAGTAGCATCAGGCCTCATCTCATGCAGCAGTCAGTTGAATACGAAAGG
AAGAAGTTTCAAGAGATTTTGGAGAGGCAACCAAATTCCCTGGACTTTGTCACCCAGTGGCTGGAAGAAGCCTCAGAGGACCTTATGACT
CAGAAGTATAAACACGCCCTGCCAGTGGGGGGAATGGCTGCTGGCTCTGGGGACATGCCCAGGCTGAGCCCTGTTGCTGTCCAGAATTAC
GCTTACCTGAAGCTTCTGAAGTGGGACCACCTCCAGAGGCCGTTCCCCGAAACAGTTTTAATGGACCAGTCTCGCTTCCACGAGCTCCAG
TTGCAGCTGGAACAACTGACCATCCTGGGGGCTGTGTTGCTGGTCACCTTCAGCATGGCAGCGCCAGGAATTTCCAGCCAGGCCGACTTT
GCTGAGAAACTCAAGATGATTGTGAAGATTTTGCTAACAGATATGCACCTGCCCTCCTTCCATCTGAAGGACGTCCTCACTACCATCGGG
GAGAAGGTGTGCCTGGAGGTGAGCAGCTGCCTCTCCCTGTGTGGGTCCTCTCCCTTCACCACGGACAAGGAGACCGTGCTCAAGGGCCAG
ATCCAGGCCGTGGCCAGTCCCGATGACCCCATTCGCAGGATCATGGAATCTCGAATCCTGACCTTCTTAGAAACCTACCTTGCCTCGGGT
CATCAGAAGCCATTGCCCACAGTCCCTGGGGGACTCAGTCCAGTTCAGAGAGAGCTGGAGGAAGTTGCTATTAAATTTGCTCGCCTGGTC
AACTATAACAAGATGGTCTTCTGTCCCTACTACGATGCAATCCTGAATATCTCAGTGAGCCTGCTGACCCTTGTGGTCACTGCCTGTGGT
CTCGCTCTCTTTGGCGTGTCTCTCTTCGTATCTTGGAAACTCTGCTGGGTTCCGTGGCGAGAACGAGGCCTGCCCTCTGGTAGCAAAGAC
AACAACCAGGAGCCCCTTAACTACATGGACACAGAGACCAATGAGCAGGAGAACAGTGAGGACTTCCTAGATCCTCCCACGCCCTGCCCT
GACTCCTCCATGAAGATCAGCCACACCTCCCCTGACATTCCCCTCTCCACCCAGACGGGGATCCAGGAGAACTGTGCCCATGGCGTCCGC
GTGCAGCGCCAAGTCACAGAGCCAACCTCGTCGGCCCGGCATAATTCAATCCGAAGACAACTCAACTTGTCAAACCCGGACTTCAATATC
CAGCAGCTTCAAAAACAGGAACAGTTGACTGGAATTGGTAGAATTAAACCAGAGTTATATAAGCAGAGGTCATTGGATAATGATGACGGG
AGACGGAGTAACAGCAAGGCTTGTGGGAAACTGAACTTCATTTTAAAATATGACTGTGACTTAGAGCAGCTCATAGTGAAGATTCACAAA
GCTGTCAATTTGCCCGCCAAGGACTTTTCTGGGACTTCAGATCCTTATGTCAAGATCTATTTGCTTCCTGATCGGAAAACAAAACACCAG
ACTAAAGTTCACAGAAAGACCCTGAACCCTGTGTTTGATGAAGTGTTTTTATTTCCGGTTCCCTACAATGACCTTGAAGCACGGAAGCTT
CACTTCTCTGTGTACGACTTTGACAGGTTCTCTCGTCATGACTTAATCGGCCAAGTGGTGGTGGATCACTTCCTAGACTTGGCTGATTTC

>89874_89874_2_TCP11L1-SYT9_TCP11L1_chr11_33094199_ENST00000324357_SYT9_chr11_7324270_ENST00000396716_length(amino acids)=587AA_BP=285
MDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEILERQPNSLDFVTQWLEEASEDLMTQKYKHALPVGGMAAGSGDMPRLSPVAVQNYA
YLKLLKWDHLQRPFPETVLMDQSRFHELQLQLEQLTILGAVLLVTFSMAAPGISSQADFAEKLKMIVKILLTDMHLPSFHLKDVLTTIGE
KVCLEVSSCLSLCGSSPFTTDKETVLKGQIQAVASPDDPIRRIMESRILTFLETYLASGHQKPLPTVPGGLSPVQRELEEVAIKFARLVN
YNKMVFCPYYDAILNISVSLLTLVVTACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPTPCPD
SSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGR
RSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLH

--------------------------------------------------------------
>89874_89874_3_TCP11L1-SYT9_TCP11L1_chr11_33094199_ENST00000531632_SYT9_chr11_7324270_ENST00000318881_length(transcript)=5291nt_BP=1718nt
TACAACGGAATCCGGACGCCGGGCGCGAGTGGAGCTCAGTGCCAGAGGAGGGGATTCCCGGCGCCGGGGGACAGAGCCCCTTTTTTCTTT
TGCCGAAAGACCCTTTCTGCTGGGGAGCCTCTTGTGTCCAGCCTAGGCCCGCGTGCAGCGCCGACGGATGACCGTCTTCTTGGAAAGTGA
ATAAACTTAATTGAGAATGTCTGAAAACCTTGACAAGTCCAATGTAAATGAAGCAGGAAAATCAAAATCCAATGATTCTGAGGAAGGCCT
CGAAGATGCTGTGGAAGGTGCTGATGAAGCCTTACAAAAAGCAATAAAGTCAGACTCCTCCAGCCCCCAAAGAGTGCAGAGACCTCACTC
TAGTCCTCCTCGCTTTGTGACAGTAGAAGAACTTCTAGAGACAGCGAGAGGTGTCACCAACATGGCTCTAGCCCATGAAATTGTAGTAAA
TGGAGACTTTCAGATTAAACCAGTTGAATTACCAGAAAACAGCTTGAAGAAGAGAGTAAAGGAGATTGTACATAAAGCGTTTTGGGATTG
CTTGAGTGTGCAGCTAAGTGAAGATCCCCCAGCATATGACCATGCTATCAAACTTGTAGGAGAAATCAAAGAGACTCTCTTATCTTTCTT
GCTGCCTGGTCATACTAGACTGAGAAACCAGATAACAGAAGTCTTGGATCTGGATCTGATAAAGCAGGAAGCAGAGAATGGGGCGCTAGA
CATTTCCAAGCTGGCAGAATTCATTATTGGCATGATGGGGACACTGTGTGCACCTGCTCGAGATGAGGAAGTTAAGAAACTAAAGGACAT
TAAGGAAATAGTGCCCCTTTTCAGAGAAATTTTTTCTGTGTTGGACCTAATGAAAGTGGACATGGCCAACTTTGCTATCAGTAGCATCAG
GCCTCATCTCATGCAGCAGTCAGTTGAATACGAAAGGAAGAAGTTTCAAGAGATTTTGGAGAGGCAACCAAATTCCCTGGACTTTGTCAC
CCAGTGGCTGGAAGAAGCCTCAGAGGACCTTATGACTCAGAAGTATAAACACGCCCTGCCAGTGGGGGGAATGGCTGCTGGCTCTGGGGA
CATGCCCAGGCTGAGCCCTGTTGCTGTCCAGAATTACGCTTACCTGAAGCTTCTGAAGTGGGACCACCTCCAGAGGCCGTTCCCCGAAAC
AGTTTTAATGGACCAGTCTCGCTTCCACGAGCTCCAGTTGCAGCTGGAACAACTGACCATCCTGGGGGCTGTGTTGCTGGTCACCTTCAG
CATGGCAGCGCCAGGAATTTCCAGCCAGGCCGACTTTGCTGAGAAACTCAAGATGATTGTGAAGATTTTGCTAACAGATATGCACCTGCC
CTCCTTCCATCTGAAGGACGTCCTCACTACCATCGGGGAGAAGGTGTGCCTGGAGGTGAGCAGCTGCCTCTCCCTGTGTGGGTCCTCTCC
CTTCACCACGGACAAGGAGACCGTGCTCAAGGGCCAGATCCAGGCCGTGGCCAGTCCCGATGACCCCATTCGCAGGATCATGGGTAAGAT
CCTCGTCCGATCCTAACGTGTATGCACCCTACAGCAGCAGTATTACTCACTAGCCACAGAATACCTGTTCTGTACTCTAATGTTGCATTG
GAAAATGGCTATATAGTACATGTCTATTTAACAGCACCGATTCCAAAGGGAAGAATATTGTGTATCACTGTTGAAAAGACTTGTTGAGAA
ATCCACTGATATCTCAGTGAGCCTGCTGACCCTTGTGGTCACTGCCTGTGGTCTCGCTCTCTTTGGCGTGTCTCTCTTCGTATCTTGGAA
ACTCTGCTGGGTTCCGTGGCGAGAACGAGGCCTGCCCTCTGGTAGCAAAGACAACAACCAGGAGCCCCTTAACTACATGGACACAGAGAC
CAATGAGCAGGAGAACAGTGAGGACTTCCTAGATCCTCCCACGCCCTGCCCTGACTCCTCCATGAAGATCAGCCACACCTCCCCTGACAT
TCCCCTCTCCACCCAGACGGGGATCCAGGAGAACTGTGCCCATGGCGTCCGCGTGCAGCGCCAAGTCACAGAGCCAACCTCGTCGGCCCG
GCATAATTCAATCCGAAGACAACTCAACTTGTCAAACCCGGACTTCAATATCCAGCAGCTTCAAAAACAGGAACAGTTGACTGGAATTGG
TAGAATTAAACCAGAGTTATATAAGCAGAGGTCATTGGATAATGATGACGGGAGACGGAGTAACAGCAAGGCTTGTGGGAAACTGAACTT
CATTTTAAAATATGACTGTGACTTAGAGCAGCTCATAGTGAAGATTCACAAAGCTGTCAATTTGCCCGCCAAGGACTTTTCTGGGACTTC
AGATCCTTATGTCAAGATCTATTTGCTTCCTGATCGGAAAACAAAACACCAGACTAAAGTTCACAGAAAGACCCTGAACCCTGTGTTTGA
TGAAGTGTTTTTATTTCCGGTTCCCTACAATGACCTTGAAGCACGGAAGCTTCACTTCTCTGTGTACGACTTTGACAGGTTCTCTCGTCA
TGACTTAATCGGCCAAGTGGTGGTGGATCACTTCCTAGACTTGGCTGATTTCCCCAGGGAGTGCATCCTTTGGAAGGATATCGAATATGT
CACCAATGACAACGTGGATCTGGGAGAGCTGATGTTTTCCCTGTGCTATCTTCCAACGGCTGGCAGGCTGACCATTACCATTATAAAAGC
AAGGAATTTAAAGGCAATGGACATAACAGGAGCATCAGATCCCTATGTGAAAGTCTCGCTGATGTGTGATGGCAGACGACTGAAGAAGAG
GAAAACATCCACCAAGAGGAACACCTTGAATCCTGTTTACAACGAAGCCATAGTCTTTGATGTCCCTCCCGAGAACATTGACCAAATCCA
CTTGTCCATAGCAGTCATGGACTATGACCGTGTAGGTCACAATGAGATCATCGGCGTGTGTCAAGTAGGCAACGAGGCTGAGAGGCTGGG
CAGAGACCACTGGAGTGAAATGTTGTCATATCCTCGGAAGCCCATTGCACACTGGCATTCCCTGGTGGAGAAACGATGACCATGGGTAAG
AGGACTGCTTGTGCCAAGGACAAAATAGGACAACCATCTCACAAAGATCTTAAGTAACTTTTTCCATCCAGCAACATCCAGACGATTTCA
GTGACCAAATGCTCAGCTGTAACCACAGCACTAACTGGCCTTCTTTCCAGATTGGGTTTGGTGAACCTGAATGGTCCAGCCACCTTCTGC
AGGTGGCCCAAGGTGATGTGCTGCAGGGAAGCATGTCTCTCATGCCAAGAACCAAGATCGGACTATGAACAAAAACAAATGATAGATATA
GTGACAGTACCAAGAGTACCAGGACTCAATGTTTCATATGAAGCCCTTGGTGATGAGGACATAGCATCTGCCCTGGAAATCGTTATTCCA
ACATAATATTATTTTCTAGAATGCCCTGGAAGGACAGAATATTTAAAAATATATCCAGGTGCTAAATAGGCAGCAGATCTCAATTCACAC
ATGACTACCTTTGAGCTAATGACTGTCTCCAGAAAATAACTGTGCCCCAAGAAGTGCTCCAGATTTGCAAGGAATAGCCCCAAGAGAATA
CCAAGACAAGCAGGCTGTTCCCTGGAAAAAATCTAATGCAAGGAGGGCTAGTTCACAGCAAATTCACTGCCTCCTCCCATGCACGTGGTA
GAGAGTACCAGTATCAACATGGCCCTGTTTTCTGCTAAAACCAGATTTTGAGGAATCAGAGACCCCCAACACTACTCACTCAGTAGCTAG
CAGCCCCTTCCTTTCAACTGGGAGTGTTATTAGAATGAAAAGTAATTAGTTAGAAGGGCATACATCTCAGTGGCATGAGCATTGTGGAAT
ATCCTTTCCTAGGCACATTCGTCCACTAAGGGAACAGCCTCAGAAACTGGTACAGCAATGGGTGAGATGAGATCATGGAGAGAGAACACA
GCCATCCCCTATAGAAAGGCACAGCTTTTGGGCTTCTCTGGCCTGAATGCCTTCTGGGGTATTTCCATATGCAACAGCCCAGAGTCATAG
CCTTGGGCAACCACACATAGAGGTTTCCTTCTCACTTCAGACACATACATCACTTTCACACCACTTGGGGATGGAAATACCTACAAGAGT
GAAGGTCAAGGGCCCTCCCCAGGCATCTCATTCATTACTCAGCTTCCTTCCTGACCAAGTCTGCCAACCAATGGCCAGCTATGCGCCTCA
TCCTCATTGCTTCTGCCTCCACGTAAATGAAACCAAAGGCCTCAGCATATCCTGGGAGGACTGGGGGCTGTTACCTAATGGTCCTCTCTG
TCCCATTATAGGTGCAAGGCACCCCATCCACACATTTGCACCACTACTCCAAGATAGTATTTTTCTTTTCACACAATCTCTTTACAGCAG
AATCCAGAGTTGGATTGTAGTTTACCTTCCTGGAAAGCTCATTATCTCTGTTTGAATTAACATTTCAGCATGGAACTAACTGGGCGGAGG
AAGGATCGTTATACGTCTTCAGAAAGTTCTCATTGCCCCAGCTGCCTAGTACTATACAAGAAGCTCTACTTTGATGGCAGATCTAAGAAG
GCTATAGGCCTTTGTTTGTAGGAAGCAGTGTCATTACATTCAAGCTTCACTTCTCTGATTGGCTTCCAACCACTGGGATTCAAAGAGAAT
CCAAGGTTCTGCCTATGTCTGATGACATAAGGAAAACTTGGCTTCCTCTGCTCAAGGTTCCCCTCTGCTCATCCCTCCTCATTCAGACAT
CCTCCACCATACCAGTGTTTAGAAGCAAAACATGAAGGGCTAGCGCCACCAGGATAGTTAGCAGAAATATTGTCTGTAAAGCTAGGCAGA
TGAGCCCAGAAGAATGGTCCCAGAGAAAGCAGACTGGCTCCAATAGATATCAGGCAGCAATCCCAATAAATTCTGACATGTCCTTGGCAA
TGGAAGCCTGGGTTGGAGATCCTGAGGCAGCTGTGCCTACTGTTCCCCACCTCAGAAGCTTCCTGCCCAGAGAGCCAGCAGCCTTGGGAT
ACTAATGAGGATGCAACTGGCTTATTGGTATGAAATAGAAGGTGGCTTTGTAGGGGCAAGCAGGCAAAGAGTACTATCCACATGGCAGGC
AGGTGGCTTTGTGTCTGGAAAGCTTTGCCTAGCCAGTACAGCTGTGAGCAGAGGCTGGTTATAAATTTGAACTCCCTCAGCCCATTTGCA

>89874_89874_3_TCP11L1-SYT9_TCP11L1_chr11_33094199_ENST00000531632_SYT9_chr11_7324270_ENST00000318881_length(amino acids)=453AA_BP=10
MLKRLVEKSTDISVSLLTLVVTACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPTPCPDSSMK
ISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNS
KACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVY
DFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMC
DGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLV

--------------------------------------------------------------
>89874_89874_4_TCP11L1-SYT9_TCP11L1_chr11_33094199_ENST00000531632_SYT9_chr11_7324270_ENST00000396716_length(transcript)=2629nt_BP=1718nt
TACAACGGAATCCGGACGCCGGGCGCGAGTGGAGCTCAGTGCCAGAGGAGGGGATTCCCGGCGCCGGGGGACAGAGCCCCTTTTTTCTTT
TGCCGAAAGACCCTTTCTGCTGGGGAGCCTCTTGTGTCCAGCCTAGGCCCGCGTGCAGCGCCGACGGATGACCGTCTTCTTGGAAAGTGA
ATAAACTTAATTGAGAATGTCTGAAAACCTTGACAAGTCCAATGTAAATGAAGCAGGAAAATCAAAATCCAATGATTCTGAGGAAGGCCT
CGAAGATGCTGTGGAAGGTGCTGATGAAGCCTTACAAAAAGCAATAAAGTCAGACTCCTCCAGCCCCCAAAGAGTGCAGAGACCTCACTC
TAGTCCTCCTCGCTTTGTGACAGTAGAAGAACTTCTAGAGACAGCGAGAGGTGTCACCAACATGGCTCTAGCCCATGAAATTGTAGTAAA
TGGAGACTTTCAGATTAAACCAGTTGAATTACCAGAAAACAGCTTGAAGAAGAGAGTAAAGGAGATTGTACATAAAGCGTTTTGGGATTG
CTTGAGTGTGCAGCTAAGTGAAGATCCCCCAGCATATGACCATGCTATCAAACTTGTAGGAGAAATCAAAGAGACTCTCTTATCTTTCTT
GCTGCCTGGTCATACTAGACTGAGAAACCAGATAACAGAAGTCTTGGATCTGGATCTGATAAAGCAGGAAGCAGAGAATGGGGCGCTAGA
CATTTCCAAGCTGGCAGAATTCATTATTGGCATGATGGGGACACTGTGTGCACCTGCTCGAGATGAGGAAGTTAAGAAACTAAAGGACAT
TAAGGAAATAGTGCCCCTTTTCAGAGAAATTTTTTCTGTGTTGGACCTAATGAAAGTGGACATGGCCAACTTTGCTATCAGTAGCATCAG
GCCTCATCTCATGCAGCAGTCAGTTGAATACGAAAGGAAGAAGTTTCAAGAGATTTTGGAGAGGCAACCAAATTCCCTGGACTTTGTCAC
CCAGTGGCTGGAAGAAGCCTCAGAGGACCTTATGACTCAGAAGTATAAACACGCCCTGCCAGTGGGGGGAATGGCTGCTGGCTCTGGGGA
CATGCCCAGGCTGAGCCCTGTTGCTGTCCAGAATTACGCTTACCTGAAGCTTCTGAAGTGGGACCACCTCCAGAGGCCGTTCCCCGAAAC
AGTTTTAATGGACCAGTCTCGCTTCCACGAGCTCCAGTTGCAGCTGGAACAACTGACCATCCTGGGGGCTGTGTTGCTGGTCACCTTCAG
CATGGCAGCGCCAGGAATTTCCAGCCAGGCCGACTTTGCTGAGAAACTCAAGATGATTGTGAAGATTTTGCTAACAGATATGCACCTGCC
CTCCTTCCATCTGAAGGACGTCCTCACTACCATCGGGGAGAAGGTGTGCCTGGAGGTGAGCAGCTGCCTCTCCCTGTGTGGGTCCTCTCC
CTTCACCACGGACAAGGAGACCGTGCTCAAGGGCCAGATCCAGGCCGTGGCCAGTCCCGATGACCCCATTCGCAGGATCATGGGTAAGAT
CCTCGTCCGATCCTAACGTGTATGCACCCTACAGCAGCAGTATTACTCACTAGCCACAGAATACCTGTTCTGTACTCTAATGTTGCATTG
GAAAATGGCTATATAGTACATGTCTATTTAACAGCACCGATTCCAAAGGGAAGAATATTGTGTATCACTGTTGAAAAGACTTGTTGAGAA
ATCCACTGATATCTCAGTGAGCCTGCTGACCCTTGTGGTCACTGCCTGTGGTCTCGCTCTCTTTGGCGTGTCTCTCTTCGTATCTTGGAA
ACTCTGCTGGGTTCCGTGGCGAGAACGAGGCCTGCCCTCTGGTAGCAAAGACAACAACCAGGAGCCCCTTAACTACATGGACACAGAGAC
CAATGAGCAGGAGAACAGTGAGGACTTCCTAGATCCTCCCACGCCCTGCCCTGACTCCTCCATGAAGATCAGCCACACCTCCCCTGACAT
TCCCCTCTCCACCCAGACGGGGATCCAGGAGAACTGTGCCCATGGCGTCCGCGTGCAGCGCCAAGTCACAGAGCCAACCTCGTCGGCCCG
GCATAATTCAATCCGAAGACAACTCAACTTGTCAAACCCGGACTTCAATATCCAGCAGCTTCAAAAACAGGAACAGTTGACTGGAATTGG
TAGAATTAAACCAGAGTTATATAAGCAGAGGTCATTGGATAATGATGACGGGAGACGGAGTAACAGCAAGGCTTGTGGGAAACTGAACTT
CATTTTAAAATATGACTGTGACTTAGAGCAGCTCATAGTGAAGATTCACAAAGCTGTCAATTTGCCCGCCAAGGACTTTTCTGGGACTTC
AGATCCTTATGTCAAGATCTATTTGCTTCCTGATCGGAAAACAAAACACCAGACTAAAGTTCACAGAAAGACCCTGAACCCTGTGTTTGA
TGAAGTGTTTTTATTTCCGGTTCCCTACAATGACCTTGAAGCACGGAAGCTTCACTTCTCTGTGTACGACTTTGACAGGTTCTCTCGTCA
TGACTTAATCGGCCAAGTGGTGGTGGATCACTTCCTAGACTTGGCTGATTTCCCCAGGGAGTGCATCCTTTGGAAGGATATCGAATATGT

>89874_89874_4_TCP11L1-SYT9_TCP11L1_chr11_33094199_ENST00000531632_SYT9_chr11_7324270_ENST00000396716_length(amino acids)=451AA_BP=
MRMSENLDKSNVNEAGKSKSNDSEEGLEDAVEGADEALQKAIKSDSSSPQRVQRPHSSPPRFVTVEELLETARGVTNMALAHEIVVNGDF
QIKPVELPENSLKKRVKEIVHKAFWDCLSVQLSEDPPAYDHAIKLVGEIKETLLSFLLPGHTRLRNQITEVLDLDLIKQEAENGALDISK
LAEFIIGMMGTLCAPARDEEVKKLKDIKEIVPLFREIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEILERQPNSLDFVTQWL
EEASEDLMTQKYKHALPVGGMAAGSGDMPRLSPVAVQNYAYLKLLKWDHLQRPFPETVLMDQSRFHELQLQLEQLTILGAVLLVTFSMAA
PGISSQADFAEKLKMIVKILLTDMHLPSFHLKDVLTTIGEKVCLEVSSCLSLCGSSPFTTDKETVLKGQIQAVASPDDPIRRIMGKILVR

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for TCP11L1-SYT9

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for TCP11L1-SYT9

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for TCP11L1-SYT9

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source