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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TDRD12-TEAD2 (FusionGDB2 ID:89927)

Fusion Gene Summary for TDRD12-TEAD2

check button Fusion gene summary
Fusion gene informationFusion gene name: TDRD12-TEAD2
Fusion gene ID: 89927
HgeneTgene
Gene symbol

TDRD12

TEAD2

Gene ID

91646

8463

Gene nametudor domain containing 12TEA domain transcription factor 2
SynonymsECAT8ETF|TEAD-2|TEF-4|TEF4
Cytomap

19q13.11

19q13.33

Type of geneprotein-codingprotein-coding
Descriptionputative ATP-dependent RNA helicase TDRD12ES cell associated transcript 8ES cell-associated transcript 8 proteintudor domain-containing protein 12transcriptional enhancer factor TEF-4TEA domain family member 2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000421545, ENST00000444215, 
ENST00000598397, ENST00000311227, 
ENST00000377214, ENST00000539846, 
ENST00000593945, ENST00000598810, 
ENST00000601519, 
Fusion gene scores* DoF score3 X 3 X 3=277 X 6 X 4=168
# samples 37
** MAII scorelog2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(7/168*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TDRD12 [Title/Abstract] AND TEAD2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTDRD12(33268135)-TEAD2(49854622), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneTEAD2

GO:0035329

hippo signaling

18579750|19324877


check buttonFusion gene breakpoints across TDRD12 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TEAD2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-V1-A9O5-06ATDRD12chr19

33268135

-TEAD2chr19

49854622

-
ChimerDB4PRADTCGA-V1-A9O5TDRD12chr19

33268135

+TEAD2chr19

49854622

-


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Fusion Gene ORF analysis for TDRD12-TEAD2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000421545ENST00000598397TDRD12chr19

33268135

+TEAD2chr19

49854622

-
5CDS-5UTRENST00000444215ENST00000598397TDRD12chr19

33268135

+TEAD2chr19

49854622

-
In-frameENST00000421545ENST00000311227TDRD12chr19

33268135

+TEAD2chr19

49854622

-
In-frameENST00000421545ENST00000377214TDRD12chr19

33268135

+TEAD2chr19

49854622

-
In-frameENST00000421545ENST00000539846TDRD12chr19

33268135

+TEAD2chr19

49854622

-
In-frameENST00000421545ENST00000593945TDRD12chr19

33268135

+TEAD2chr19

49854622

-
In-frameENST00000421545ENST00000598810TDRD12chr19

33268135

+TEAD2chr19

49854622

-
In-frameENST00000421545ENST00000601519TDRD12chr19

33268135

+TEAD2chr19

49854622

-
In-frameENST00000444215ENST00000311227TDRD12chr19

33268135

+TEAD2chr19

49854622

-
In-frameENST00000444215ENST00000377214TDRD12chr19

33268135

+TEAD2chr19

49854622

-
In-frameENST00000444215ENST00000539846TDRD12chr19

33268135

+TEAD2chr19

49854622

-
In-frameENST00000444215ENST00000593945TDRD12chr19

33268135

+TEAD2chr19

49854622

-
In-frameENST00000444215ENST00000598810TDRD12chr19

33268135

+TEAD2chr19

49854622

-
In-frameENST00000444215ENST00000601519TDRD12chr19

33268135

+TEAD2chr19

49854622

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000444215TDRD12chr1933268135+ENST00000598810TEAD2chr1949854622-29871441142257747
ENST00000444215TDRD12chr1933268135+ENST00000593945TEAD2chr1949854622-29871441142257747
ENST00000444215TDRD12chr1933268135+ENST00000601519TEAD2chr1949854622-29871441142257747
ENST00000444215TDRD12chr1933268135+ENST00000311227TEAD2chr1949854622-29871441142257747
ENST00000444215TDRD12chr1933268135+ENST00000377214TEAD2chr1949854622-29821441142257747
ENST00000444215TDRD12chr1933268135+ENST00000539846TEAD2chr1949854622-25001441142257747
ENST00000421545TDRD12chr1933268135+ENST00000598810TEAD2chr1949854622-2667112101937645
ENST00000421545TDRD12chr1933268135+ENST00000593945TEAD2chr1949854622-2667112101937645
ENST00000421545TDRD12chr1933268135+ENST00000601519TEAD2chr1949854622-2667112101937645
ENST00000421545TDRD12chr1933268135+ENST00000311227TEAD2chr1949854622-2667112101937645
ENST00000421545TDRD12chr1933268135+ENST00000377214TEAD2chr1949854622-2662112101937645
ENST00000421545TDRD12chr1933268135+ENST00000539846TEAD2chr1949854622-2180112101937645

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000444215ENST00000598810TDRD12chr1933268135+TEAD2chr1949854622-0.0006530530.9993469
ENST00000444215ENST00000593945TDRD12chr1933268135+TEAD2chr1949854622-0.0006530530.9993469
ENST00000444215ENST00000601519TDRD12chr1933268135+TEAD2chr1949854622-0.0006530530.9993469
ENST00000444215ENST00000311227TDRD12chr1933268135+TEAD2chr1949854622-0.0006530530.9993469
ENST00000444215ENST00000377214TDRD12chr1933268135+TEAD2chr1949854622-0.0006673570.9993326
ENST00000444215ENST00000539846TDRD12chr1933268135+TEAD2chr1949854622-0.0008133010.9991867
ENST00000421545ENST00000598810TDRD12chr1933268135+TEAD2chr1949854622-0.0004891360.9995109
ENST00000421545ENST00000593945TDRD12chr1933268135+TEAD2chr1949854622-0.0004891360.9995109
ENST00000421545ENST00000601519TDRD12chr1933268135+TEAD2chr1949854622-0.0004891360.9995109
ENST00000421545ENST00000311227TDRD12chr1933268135+TEAD2chr1949854622-0.0004891360.9995109
ENST00000421545ENST00000377214TDRD12chr1933268135+TEAD2chr1949854622-0.0004967410.99950325
ENST00000421545ENST00000539846TDRD12chr1933268135+TEAD2chr1949854622-0.0005654090.99943453

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Fusion Genomic Features for TDRD12-TEAD2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TDRD12-TEAD2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:33268135/chr19:49854622)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTDRD12chr19:33268135chr19:49854622ENST00000421545+111356_118373396.0DomainNote=Tudor 1
HgeneTDRD12chr19:33268135chr19:49854622ENST00000444215+112856_1183731178.0DomainNote=Tudor 1
TgeneTEAD2chr19:33268135chr19:49854622ENST00000539846512152_21647320.0Compositional biasNote=Pro-rich
TgeneTEAD2chr19:33268135chr19:49854622ENST00000539846512172_44747320.0RegionTranscriptional activation

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTDRD12chr19:33268135chr19:49854622ENST00000421545+1113447_635373396.0DomainNote=Helicase ATP-binding
HgeneTDRD12chr19:33268135chr19:49854622ENST00000421545+1113900_999373396.0DomainNote=Tudor 2
HgeneTDRD12chr19:33268135chr19:49854622ENST00000444215+1128447_6353731178.0DomainNote=Helicase ATP-binding
HgeneTDRD12chr19:33268135chr19:49854622ENST00000444215+1128900_9993731178.0DomainNote=Tudor 2
HgeneTDRD12chr19:33268135chr19:49854622ENST00000421545+1113574_577373396.0MotifNote=DEAH box
HgeneTDRD12chr19:33268135chr19:49854622ENST00000444215+1128574_5773731178.0MotifNote=DEAH box
HgeneTDRD12chr19:33268135chr19:49854622ENST00000421545+1113460_467373396.0Nucleotide bindingATP
HgeneTDRD12chr19:33268135chr19:49854622ENST00000444215+1128460_4673731178.0Nucleotide bindingATP
TgeneTEAD2chr19:33268135chr19:49854622ENST00000311227512152_216175448.0Compositional biasNote=Pro-rich
TgeneTEAD2chr19:33268135chr19:49854622ENST00000377214411152_216178451.0Compositional biasNote=Pro-rich
TgeneTEAD2chr19:33268135chr19:49854622ENST00000601519512152_216178451.0Compositional biasNote=Pro-rich
TgeneTEAD2chr19:33268135chr19:49854622ENST0000031122751238_114175448.0DNA bindingTEA
TgeneTEAD2chr19:33268135chr19:49854622ENST0000037721441138_114178451.0DNA bindingTEA
TgeneTEAD2chr19:33268135chr19:49854622ENST0000053984651238_11447320.0DNA bindingTEA
TgeneTEAD2chr19:33268135chr19:49854622ENST0000060151951238_114178451.0DNA bindingTEA
TgeneTEAD2chr19:33268135chr19:49854622ENST00000311227512172_447175448.0RegionTranscriptional activation
TgeneTEAD2chr19:33268135chr19:49854622ENST00000377214411172_447178451.0RegionTranscriptional activation
TgeneTEAD2chr19:33268135chr19:49854622ENST00000601519512172_447178451.0RegionTranscriptional activation


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Fusion Gene Sequence for TDRD12-TEAD2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>89927_89927_1_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000421545_TEAD2_chr19_49854622_ENST00000311227_length(transcript)=2667nt_BP=1121nt
ATGCTCCAGCTCCTGGTGCTGAAGATTGAAGATCCAGGTTGCTTCTGGGTTATTATAAAAGGGTGTAGTCCCTTTTTAGATCATGATGTC
GATTATCAAAAATTAAATAGTGCCATGAATGACTTCTACAACAGCACGTGTCAAGATATAGAAATAAAACCCTTAACATTGGAAGAAGGA
CAGGTGTGTGTGGTCTATTGTGAGGAGCTAAAGTGCTGGTGCAGGGCCATTGTCAAATCAATTACGTCTTCCGCAGACCAGTACCTGGCA
GAATGTTTCCTTGTGGACTTTGCCAAGAACATTCCAGTCAAATCTAAAAACATCCGAGTTGTAGTAGAATCGTTTATGCAGCTTCCCTAT
AGAGCAAAAAAATTCAGCCTGTACTGCACAAAGCCTGTCACATTACACATTGACTTCTGCCGAGACAGTACTGACATTGTACCTGCCAAG
AAGTGGGACAATGCAGCTATTCAGTACTTTCAGAACCTTCTGAAAGCAACTACCCAGGTGGAAGCCAGATTATGTGCTGTGGAAGAAGAT
ACATTTGAGGTTTACCTTTATGTAACTATAAAAGATGAAAAAGTTTGTGTTAATGATGATCTTGTTGCAAAGAACTATGCTTGTTATATG
TCACCTACAAAGAATAAAAACCTTGATTATTTAGAAAAACCAAGATTGAATATAAAATCAGCACCCTCCTTCAATAAACTCAATCCAGCA
CTTACACTCTGGCCAATGTTTTTGCAAGGAAAAGATGTTCAAGGAATGGAAGATTCACATGGTGTAAATTTTCCGGCACAATCTCTGCAA
CATACATGGTGCAAGGGTATTGTCGGTGACCTCAGGCCAACAGCCACAGCACAGGACAAAGCTGTAAAATGTAATATGGATTCATTGAGA
GATTCACCTAAAGACAAATCTGAAAAGAAACACCATTGCATCTCTTTAAAAGATACAAATAAGCGTGTTGAATCCTCAGTGTACTGGCCA
GCAAAAAGAGGCATAACCATATATGCTGATCCAGATGTACCAGAAGCAAGTGCTTTAAGTCAGAAGTCAAATGAGAAACCTCTTAGATTG
ACTGAGAAGAAAGAATATGATGAGAAGAATAGCTGTGTGAATGTGAAGCCATTCTCACAGACACCGTTCACCTTGTCACTGACTCCCCCA
TCTACTGACCTCCCAGGGTACGAGCCCCCCCAAGCCCTCTCACCCCTGCCCCCACCTACCCCATCGCCCCCAGCCTGGCAGGCTCGGGGC
CTGGGCACCGCCCGGTTGCAGCTGGTAGAGTTCTCAGCCTTCGTGGAACCGCCAGATGCAGTTGATTCTTACCAGAGGCACCTGTTCGTG
CACATCAGCCAGCACTGCCCCAGCCCCGGAGCGCCGCCGCTCGAGAGTGTGGACGTCCGGCAGATCTACGACAAATTCCCTGAGAAAAAG
GGTGGCCTCCGAGAGCTATATGATCGTGGCCCCCCCCATGCCTTCTTCCTGGTCAAGTTCTGGGCGGACCTGAACTGGGGCCCAAGTGGT
GAGGAGGCAGGGGCCGGTGGCAGCATCAGCAGTGGTGGCTTCTACGGAGTGAGCAGCCAGTATGAGAGCCTGGAACACATGACCCTCACC
TGTTCCTCCAAGGTCTGCTCTTTTGGCAAGCAGGTGGTGGAGAAGGTGGAGACGGAACGGGCCCAGCTGGAGGACGGCAGATTTGTGTAC
CGCCTGCTGCGCTCGCCCATGTGCGAGTACCTGGTGAATTTCTTGCACAAGTTGCGGCAGCTGCCTGAGCGATACATGATGAACAGCGTC
CTGGAAAACTTCACCATCCTCCAGGTGGTGACAAACAGAGACACCCAGGAACTGCTGCTCTGCACCGCCTATGTCTTCGAGGTCTCCACC
AGCGAGCGTGGGGCCCAGCATCACATTTACCGCCTGGTCAGGGACTGAAGGGGGACCCCAAAACTGGCTCACCCCCCAGAACACCCTCCT
CCCAGGGAGGGTCCTCCAGCTCACCTCATGCTTCTTATTTGGGGAGAGGGCTGTGATGTAAAGGGGTTGACCTCAGAGGCCTAAGCAACT
GGGGCCATCCCCCCCATTAGAGGGGCCCCCAAAACTTGGTTGGAGAGCTGAACAGGCTGGGACTGAGGAAAGGATAAACCCCGATATTGG
GACCTCACAGTGGGTGTCTGAAAGGACAGATCACTCCGGAGTATCAGGGATTGTGGGGACAGGAGTGAGACAACCCCCCAGGTACAGCAC
TGGCTTTTCTTTTCAGCCCCTGACAGGCCACCCCCACTCCTCTGCATGTCTTGGAGAGCGCTAGTTACACATTGGCTTGTCCCCTTTACT
TTTTCCCAGCCACCCCTCCCCCTGAAATTTCTGCCCCTCTCTACCACCCTCACTCCATGACCTGTGAGATCACAAAGTGAAGATGAACCC
TTTCTGTGCAGGAGCAGAGCCAGGTGGGCCCTGGACATTTTTTTTTTTTTTAATATAACGAGATATTTATAAGTGGGTGCTAGGGTCTTG
ACTTTATCTCCGCTGCACAAGCAGTGTGTTGAACTTTCTAATCTCATCCCTCTCCTAAGTGAGCCCTGAGCTAGACGGTTTCCTTCCTCC

>89927_89927_1_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000421545_TEAD2_chr19_49854622_ENST00000311227_length(amino acids)=645AA_BP=374
MLQLLVLKIEDPGCFWVIIKGCSPFLDHDVDYQKLNSAMNDFYNSTCQDIEIKPLTLEEGQVCVVYCEELKCWCRAIVKSITSSADQYLA
ECFLVDFAKNIPVKSKNIRVVVESFMQLPYRAKKFSLYCTKPVTLHIDFCRDSTDIVPAKKWDNAAIQYFQNLLKATTQVEARLCAVEED
TFEVYLYVTIKDEKVCVNDDLVAKNYACYMSPTKNKNLDYLEKPRLNIKSAPSFNKLNPALTLWPMFLQGKDVQGMEDSHGVNFPAQSLQ
HTWCKGIVGDLRPTATAQDKAVKCNMDSLRDSPKDKSEKKHHCISLKDTNKRVESSVYWPAKRGITIYADPDVPEASALSQKSNEKPLRL
TEKKEYDEKNSCVNVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFV
HISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLT
CSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVST

--------------------------------------------------------------
>89927_89927_2_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000421545_TEAD2_chr19_49854622_ENST00000377214_length(transcript)=2662nt_BP=1121nt
ATGCTCCAGCTCCTGGTGCTGAAGATTGAAGATCCAGGTTGCTTCTGGGTTATTATAAAAGGGTGTAGTCCCTTTTTAGATCATGATGTC
GATTATCAAAAATTAAATAGTGCCATGAATGACTTCTACAACAGCACGTGTCAAGATATAGAAATAAAACCCTTAACATTGGAAGAAGGA
CAGGTGTGTGTGGTCTATTGTGAGGAGCTAAAGTGCTGGTGCAGGGCCATTGTCAAATCAATTACGTCTTCCGCAGACCAGTACCTGGCA
GAATGTTTCCTTGTGGACTTTGCCAAGAACATTCCAGTCAAATCTAAAAACATCCGAGTTGTAGTAGAATCGTTTATGCAGCTTCCCTAT
AGAGCAAAAAAATTCAGCCTGTACTGCACAAAGCCTGTCACATTACACATTGACTTCTGCCGAGACAGTACTGACATTGTACCTGCCAAG
AAGTGGGACAATGCAGCTATTCAGTACTTTCAGAACCTTCTGAAAGCAACTACCCAGGTGGAAGCCAGATTATGTGCTGTGGAAGAAGAT
ACATTTGAGGTTTACCTTTATGTAACTATAAAAGATGAAAAAGTTTGTGTTAATGATGATCTTGTTGCAAAGAACTATGCTTGTTATATG
TCACCTACAAAGAATAAAAACCTTGATTATTTAGAAAAACCAAGATTGAATATAAAATCAGCACCCTCCTTCAATAAACTCAATCCAGCA
CTTACACTCTGGCCAATGTTTTTGCAAGGAAAAGATGTTCAAGGAATGGAAGATTCACATGGTGTAAATTTTCCGGCACAATCTCTGCAA
CATACATGGTGCAAGGGTATTGTCGGTGACCTCAGGCCAACAGCCACAGCACAGGACAAAGCTGTAAAATGTAATATGGATTCATTGAGA
GATTCACCTAAAGACAAATCTGAAAAGAAACACCATTGCATCTCTTTAAAAGATACAAATAAGCGTGTTGAATCCTCAGTGTACTGGCCA
GCAAAAAGAGGCATAACCATATATGCTGATCCAGATGTACCAGAAGCAAGTGCTTTAAGTCAGAAGTCAAATGAGAAACCTCTTAGATTG
ACTGAGAAGAAAGAATATGATGAGAAGAATAGCTGTGTGAATGTGAAGCCATTCTCACAGACACCGTTCACCTTGTCACTGACTCCCCCA
TCTACTGACCTCCCAGGGTACGAGCCCCCCCAAGCCCTCTCACCCCTGCCCCCACCTACCCCATCGCCCCCAGCCTGGCAGGCTCGGGGC
CTGGGCACCGCCCGGTTGCAGCTGGTAGAGTTCTCAGCCTTCGTGGAACCGCCAGATGCAGTTGATTCTTACCAGAGGCACCTGTTCGTG
CACATCAGCCAGCACTGCCCCAGCCCCGGAGCGCCGCCGCTCGAGAGTGTGGACGTCCGGCAGATCTACGACAAATTCCCTGAGAAAAAG
GGTGGCCTCCGAGAGCTATATGATCGTGGCCCCCCCCATGCCTTCTTCCTGGTCAAGTTCTGGGCGGACCTGAACTGGGGCCCAAGTGGT
GAGGAGGCAGGGGCCGGTGGCAGCATCAGCAGTGGTGGCTTCTACGGAGTGAGCAGCCAGTATGAGAGCCTGGAACACATGACCCTCACC
TGTTCCTCCAAGGTCTGCTCTTTTGGCAAGCAGGTGGTGGAGAAGGTGGAGACGGAACGGGCCCAGCTGGAGGACGGCAGATTTGTGTAC
CGCCTGCTGCGCTCGCCCATGTGCGAGTACCTGGTGAATTTCTTGCACAAGTTGCGGCAGCTGCCTGAGCGATACATGATGAACAGCGTC
CTGGAAAACTTCACCATCCTCCAGGTGGTGACAAACAGAGACACCCAGGAACTGCTGCTCTGCACCGCCTATGTCTTCGAGGTCTCCACC
AGCGAGCGTGGGGCCCAGCATCACATTTACCGCCTGGTCAGGGACTGAAGGGGGACCCCAAAACTGGCTCACCCCCCAGAACACCCTCCT
CCCAGGGAGGGTCCTCCAGCTCACCTCATGCTTCTTATTTGGGGAGAGGGCTGTGATGTAAAGGGGTTGACCTCAGAGGCCTAAGCAACT
GGGGCCATCCCCCCCATTAGAGGGGCCCCCAAAACTTGGTTGGAGAGCTGAACAGGCTGGGACTGAGGAAAGGATAAACCCCGATATTGG
GACCTCACAGTGGGTGTCTGAAAGGACAGATCACTCCGGAGTATCAGGGATTGTGGGGACAGGAGTGAGACAACCCCCCAGGTACAGCAC
TGGCTTTTCTTTTCAGCCCCTGACAGGCCACCCCCACTCCTCTGCATGTCTTGGAGAGCGCTAGTTACACATTGGCTTGTCCCCTTTACT
TTTTCCCAGCCACCCCTCCCCCTGAAATTTCTGCCCCTCTCTACCACCCTCACTCCATGACCTGTGAGATCACAAAGTGAAGATGAACCC
TTTCTGTGCAGGAGCAGAGCCAGGTGGGCCCTGGACATTTTTTTTTTTTTTAATATAACGAGATATTTATAAGTGGGTGCTAGGGTCTTG
ACTTTATCTCCGCTGCACAAGCAGTGTGTTGAACTTTCTAATCTCATCCCTCTCCTAAGTGAGCCCTGAGCTAGACGGTTTCCTTCCTCC

>89927_89927_2_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000421545_TEAD2_chr19_49854622_ENST00000377214_length(amino acids)=645AA_BP=374
MLQLLVLKIEDPGCFWVIIKGCSPFLDHDVDYQKLNSAMNDFYNSTCQDIEIKPLTLEEGQVCVVYCEELKCWCRAIVKSITSSADQYLA
ECFLVDFAKNIPVKSKNIRVVVESFMQLPYRAKKFSLYCTKPVTLHIDFCRDSTDIVPAKKWDNAAIQYFQNLLKATTQVEARLCAVEED
TFEVYLYVTIKDEKVCVNDDLVAKNYACYMSPTKNKNLDYLEKPRLNIKSAPSFNKLNPALTLWPMFLQGKDVQGMEDSHGVNFPAQSLQ
HTWCKGIVGDLRPTATAQDKAVKCNMDSLRDSPKDKSEKKHHCISLKDTNKRVESSVYWPAKRGITIYADPDVPEASALSQKSNEKPLRL
TEKKEYDEKNSCVNVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFV
HISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLT
CSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVST

--------------------------------------------------------------
>89927_89927_3_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000421545_TEAD2_chr19_49854622_ENST00000539846_length(transcript)=2180nt_BP=1121nt
ATGCTCCAGCTCCTGGTGCTGAAGATTGAAGATCCAGGTTGCTTCTGGGTTATTATAAAAGGGTGTAGTCCCTTTTTAGATCATGATGTC
GATTATCAAAAATTAAATAGTGCCATGAATGACTTCTACAACAGCACGTGTCAAGATATAGAAATAAAACCCTTAACATTGGAAGAAGGA
CAGGTGTGTGTGGTCTATTGTGAGGAGCTAAAGTGCTGGTGCAGGGCCATTGTCAAATCAATTACGTCTTCCGCAGACCAGTACCTGGCA
GAATGTTTCCTTGTGGACTTTGCCAAGAACATTCCAGTCAAATCTAAAAACATCCGAGTTGTAGTAGAATCGTTTATGCAGCTTCCCTAT
AGAGCAAAAAAATTCAGCCTGTACTGCACAAAGCCTGTCACATTACACATTGACTTCTGCCGAGACAGTACTGACATTGTACCTGCCAAG
AAGTGGGACAATGCAGCTATTCAGTACTTTCAGAACCTTCTGAAAGCAACTACCCAGGTGGAAGCCAGATTATGTGCTGTGGAAGAAGAT
ACATTTGAGGTTTACCTTTATGTAACTATAAAAGATGAAAAAGTTTGTGTTAATGATGATCTTGTTGCAAAGAACTATGCTTGTTATATG
TCACCTACAAAGAATAAAAACCTTGATTATTTAGAAAAACCAAGATTGAATATAAAATCAGCACCCTCCTTCAATAAACTCAATCCAGCA
CTTACACTCTGGCCAATGTTTTTGCAAGGAAAAGATGTTCAAGGAATGGAAGATTCACATGGTGTAAATTTTCCGGCACAATCTCTGCAA
CATACATGGTGCAAGGGTATTGTCGGTGACCTCAGGCCAACAGCCACAGCACAGGACAAAGCTGTAAAATGTAATATGGATTCATTGAGA
GATTCACCTAAAGACAAATCTGAAAAGAAACACCATTGCATCTCTTTAAAAGATACAAATAAGCGTGTTGAATCCTCAGTGTACTGGCCA
GCAAAAAGAGGCATAACCATATATGCTGATCCAGATGTACCAGAAGCAAGTGCTTTAAGTCAGAAGTCAAATGAGAAACCTCTTAGATTG
ACTGAGAAGAAAGAATATGATGAGAAGAATAGCTGTGTGAATGTGAAGCCATTCTCACAGACACCGTTCACCTTGTCACTGACTCCCCCA
TCTACTGACCTCCCAGGGTACGAGCCCCCCCAAGCCCTCTCACCCCTGCCCCCACCTACCCCATCGCCCCCAGCCTGGCAGGCTCGGGGC
CTGGGCACCGCCCGGTTGCAGCTGGTAGAGTTCTCAGCCTTCGTGGAACCGCCAGATGCAGTTGATTCTTACCAGAGGCACCTGTTCGTG
CACATCAGCCAGCACTGCCCCAGCCCCGGAGCGCCGCCGCTCGAGAGTGTGGACGTCCGGCAGATCTACGACAAATTCCCTGAGAAAAAG
GGTGGCCTCCGAGAGCTATATGATCGTGGCCCCCCCCATGCCTTCTTCCTGGTCAAGTTCTGGGCGGACCTGAACTGGGGCCCAAGTGGT
GAGGAGGCAGGGGCCGGTGGCAGCATCAGCAGTGGTGGCTTCTACGGAGTGAGCAGCCAGTATGAGAGCCTGGAACACATGACCCTCACC
TGTTCCTCCAAGGTCTGCTCTTTTGGCAAGCAGGTGGTGGAGAAGGTGGAGACGGAACGGGCCCAGCTGGAGGACGGCAGATTTGTGTAC
CGCCTGCTGCGCTCGCCCATGTGCGAGTACCTGGTGAATTTCTTGCACAAGTTGCGGCAGCTGCCTGAGCGATACATGATGAACAGCGTC
CTGGAAAACTTCACCATCCTCCAGGTGGTGACAAACAGAGACACCCAGGAACTGCTGCTCTGCACCGCCTATGTCTTCGAGGTCTCCACC
AGCGAGCGTGGGGCCCAGCATCACATTTACCGCCTGGTCAGGGACTGAAGGGGGACCCCAAAACTGGCTCACCCCCCAGAACACCCTCCT
CCCAGGGAGGGTCCTCCAGCTCACCTCATGCTTCTTATTTGGGGAGAGGGCTGTGATGTAAAGGGGTTGACCTCAGAGGCCTAAGCAACT
GGGGCCATCCCCCCCATTAGAGGGGCCCCCAAAACTTGGTTGGAGAGCTGAACAGGCTGGGACTGAGGAAAGGATAAACCCCGATATTGG

>89927_89927_3_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000421545_TEAD2_chr19_49854622_ENST00000539846_length(amino acids)=645AA_BP=374
MLQLLVLKIEDPGCFWVIIKGCSPFLDHDVDYQKLNSAMNDFYNSTCQDIEIKPLTLEEGQVCVVYCEELKCWCRAIVKSITSSADQYLA
ECFLVDFAKNIPVKSKNIRVVVESFMQLPYRAKKFSLYCTKPVTLHIDFCRDSTDIVPAKKWDNAAIQYFQNLLKATTQVEARLCAVEED
TFEVYLYVTIKDEKVCVNDDLVAKNYACYMSPTKNKNLDYLEKPRLNIKSAPSFNKLNPALTLWPMFLQGKDVQGMEDSHGVNFPAQSLQ
HTWCKGIVGDLRPTATAQDKAVKCNMDSLRDSPKDKSEKKHHCISLKDTNKRVESSVYWPAKRGITIYADPDVPEASALSQKSNEKPLRL
TEKKEYDEKNSCVNVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFV
HISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLT
CSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVST

--------------------------------------------------------------
>89927_89927_4_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000421545_TEAD2_chr19_49854622_ENST00000593945_length(transcript)=2667nt_BP=1121nt
ATGCTCCAGCTCCTGGTGCTGAAGATTGAAGATCCAGGTTGCTTCTGGGTTATTATAAAAGGGTGTAGTCCCTTTTTAGATCATGATGTC
GATTATCAAAAATTAAATAGTGCCATGAATGACTTCTACAACAGCACGTGTCAAGATATAGAAATAAAACCCTTAACATTGGAAGAAGGA
CAGGTGTGTGTGGTCTATTGTGAGGAGCTAAAGTGCTGGTGCAGGGCCATTGTCAAATCAATTACGTCTTCCGCAGACCAGTACCTGGCA
GAATGTTTCCTTGTGGACTTTGCCAAGAACATTCCAGTCAAATCTAAAAACATCCGAGTTGTAGTAGAATCGTTTATGCAGCTTCCCTAT
AGAGCAAAAAAATTCAGCCTGTACTGCACAAAGCCTGTCACATTACACATTGACTTCTGCCGAGACAGTACTGACATTGTACCTGCCAAG
AAGTGGGACAATGCAGCTATTCAGTACTTTCAGAACCTTCTGAAAGCAACTACCCAGGTGGAAGCCAGATTATGTGCTGTGGAAGAAGAT
ACATTTGAGGTTTACCTTTATGTAACTATAAAAGATGAAAAAGTTTGTGTTAATGATGATCTTGTTGCAAAGAACTATGCTTGTTATATG
TCACCTACAAAGAATAAAAACCTTGATTATTTAGAAAAACCAAGATTGAATATAAAATCAGCACCCTCCTTCAATAAACTCAATCCAGCA
CTTACACTCTGGCCAATGTTTTTGCAAGGAAAAGATGTTCAAGGAATGGAAGATTCACATGGTGTAAATTTTCCGGCACAATCTCTGCAA
CATACATGGTGCAAGGGTATTGTCGGTGACCTCAGGCCAACAGCCACAGCACAGGACAAAGCTGTAAAATGTAATATGGATTCATTGAGA
GATTCACCTAAAGACAAATCTGAAAAGAAACACCATTGCATCTCTTTAAAAGATACAAATAAGCGTGTTGAATCCTCAGTGTACTGGCCA
GCAAAAAGAGGCATAACCATATATGCTGATCCAGATGTACCAGAAGCAAGTGCTTTAAGTCAGAAGTCAAATGAGAAACCTCTTAGATTG
ACTGAGAAGAAAGAATATGATGAGAAGAATAGCTGTGTGAATGTGAAGCCATTCTCACAGACACCGTTCACCTTGTCACTGACTCCCCCA
TCTACTGACCTCCCAGGGTACGAGCCCCCCCAAGCCCTCTCACCCCTGCCCCCACCTACCCCATCGCCCCCAGCCTGGCAGGCTCGGGGC
CTGGGCACCGCCCGGTTGCAGCTGGTAGAGTTCTCAGCCTTCGTGGAACCGCCAGATGCAGTTGATTCTTACCAGAGGCACCTGTTCGTG
CACATCAGCCAGCACTGCCCCAGCCCCGGAGCGCCGCCGCTCGAGAGTGTGGACGTCCGGCAGATCTACGACAAATTCCCTGAGAAAAAG
GGTGGCCTCCGAGAGCTATATGATCGTGGCCCCCCCCATGCCTTCTTCCTGGTCAAGTTCTGGGCGGACCTGAACTGGGGCCCAAGTGGT
GAGGAGGCAGGGGCCGGTGGCAGCATCAGCAGTGGTGGCTTCTACGGAGTGAGCAGCCAGTATGAGAGCCTGGAACACATGACCCTCACC
TGTTCCTCCAAGGTCTGCTCTTTTGGCAAGCAGGTGGTGGAGAAGGTGGAGACGGAACGGGCCCAGCTGGAGGACGGCAGATTTGTGTAC
CGCCTGCTGCGCTCGCCCATGTGCGAGTACCTGGTGAATTTCTTGCACAAGTTGCGGCAGCTGCCTGAGCGATACATGATGAACAGCGTC
CTGGAAAACTTCACCATCCTCCAGGTGGTGACAAACAGAGACACCCAGGAACTGCTGCTCTGCACCGCCTATGTCTTCGAGGTCTCCACC
AGCGAGCGTGGGGCCCAGCATCACATTTACCGCCTGGTCAGGGACTGAAGGGGGACCCCAAAACTGGCTCACCCCCCAGAACACCCTCCT
CCCAGGGAGGGTCCTCCAGCTCACCTCATGCTTCTTATTTGGGGAGAGGGCTGTGATGTAAAGGGGTTGACCTCAGAGGCCTAAGCAACT
GGGGCCATCCCCCCCATTAGAGGGGCCCCCAAAACTTGGTTGGAGAGCTGAACAGGCTGGGACTGAGGAAAGGATAAACCCCGATATTGG
GACCTCACAGTGGGTGTCTGAAAGGACAGATCACTCCGGAGTATCAGGGATTGTGGGGACAGGAGTGAGACAACCCCCCAGGTACAGCAC
TGGCTTTTCTTTTCAGCCCCTGACAGGCCACCCCCACTCCTCTGCATGTCTTGGAGAGCGCTAGTTACACATTGGCTTGTCCCCTTTACT
TTTTCCCAGCCACCCCTCCCCCTGAAATTTCTGCCCCTCTCTACCACCCTCACTCCATGACCTGTGAGATCACAAAGTGAAGATGAACCC
TTTCTGTGCAGGAGCAGAGCCAGGTGGGCCCTGGACATTTTTTTTTTTTTTAATATAACGAGATATTTATAAGTGGGTGCTAGGGTCTTG
ACTTTATCTCCGCTGCACAAGCAGTGTGTTGAACTTTCTAATCTCATCCCTCTCCTAAGTGAGCCCTGAGCTAGACGGTTTCCTTCCTCC

>89927_89927_4_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000421545_TEAD2_chr19_49854622_ENST00000593945_length(amino acids)=645AA_BP=374
MLQLLVLKIEDPGCFWVIIKGCSPFLDHDVDYQKLNSAMNDFYNSTCQDIEIKPLTLEEGQVCVVYCEELKCWCRAIVKSITSSADQYLA
ECFLVDFAKNIPVKSKNIRVVVESFMQLPYRAKKFSLYCTKPVTLHIDFCRDSTDIVPAKKWDNAAIQYFQNLLKATTQVEARLCAVEED
TFEVYLYVTIKDEKVCVNDDLVAKNYACYMSPTKNKNLDYLEKPRLNIKSAPSFNKLNPALTLWPMFLQGKDVQGMEDSHGVNFPAQSLQ
HTWCKGIVGDLRPTATAQDKAVKCNMDSLRDSPKDKSEKKHHCISLKDTNKRVESSVYWPAKRGITIYADPDVPEASALSQKSNEKPLRL
TEKKEYDEKNSCVNVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFV
HISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLT
CSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVST

--------------------------------------------------------------
>89927_89927_5_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000421545_TEAD2_chr19_49854622_ENST00000598810_length(transcript)=2667nt_BP=1121nt
ATGCTCCAGCTCCTGGTGCTGAAGATTGAAGATCCAGGTTGCTTCTGGGTTATTATAAAAGGGTGTAGTCCCTTTTTAGATCATGATGTC
GATTATCAAAAATTAAATAGTGCCATGAATGACTTCTACAACAGCACGTGTCAAGATATAGAAATAAAACCCTTAACATTGGAAGAAGGA
CAGGTGTGTGTGGTCTATTGTGAGGAGCTAAAGTGCTGGTGCAGGGCCATTGTCAAATCAATTACGTCTTCCGCAGACCAGTACCTGGCA
GAATGTTTCCTTGTGGACTTTGCCAAGAACATTCCAGTCAAATCTAAAAACATCCGAGTTGTAGTAGAATCGTTTATGCAGCTTCCCTAT
AGAGCAAAAAAATTCAGCCTGTACTGCACAAAGCCTGTCACATTACACATTGACTTCTGCCGAGACAGTACTGACATTGTACCTGCCAAG
AAGTGGGACAATGCAGCTATTCAGTACTTTCAGAACCTTCTGAAAGCAACTACCCAGGTGGAAGCCAGATTATGTGCTGTGGAAGAAGAT
ACATTTGAGGTTTACCTTTATGTAACTATAAAAGATGAAAAAGTTTGTGTTAATGATGATCTTGTTGCAAAGAACTATGCTTGTTATATG
TCACCTACAAAGAATAAAAACCTTGATTATTTAGAAAAACCAAGATTGAATATAAAATCAGCACCCTCCTTCAATAAACTCAATCCAGCA
CTTACACTCTGGCCAATGTTTTTGCAAGGAAAAGATGTTCAAGGAATGGAAGATTCACATGGTGTAAATTTTCCGGCACAATCTCTGCAA
CATACATGGTGCAAGGGTATTGTCGGTGACCTCAGGCCAACAGCCACAGCACAGGACAAAGCTGTAAAATGTAATATGGATTCATTGAGA
GATTCACCTAAAGACAAATCTGAAAAGAAACACCATTGCATCTCTTTAAAAGATACAAATAAGCGTGTTGAATCCTCAGTGTACTGGCCA
GCAAAAAGAGGCATAACCATATATGCTGATCCAGATGTACCAGAAGCAAGTGCTTTAAGTCAGAAGTCAAATGAGAAACCTCTTAGATTG
ACTGAGAAGAAAGAATATGATGAGAAGAATAGCTGTGTGAATGTGAAGCCATTCTCACAGACACCGTTCACCTTGTCACTGACTCCCCCA
TCTACTGACCTCCCAGGGTACGAGCCCCCCCAAGCCCTCTCACCCCTGCCCCCACCTACCCCATCGCCCCCAGCCTGGCAGGCTCGGGGC
CTGGGCACCGCCCGGTTGCAGCTGGTAGAGTTCTCAGCCTTCGTGGAACCGCCAGATGCAGTTGATTCTTACCAGAGGCACCTGTTCGTG
CACATCAGCCAGCACTGCCCCAGCCCCGGAGCGCCGCCGCTCGAGAGTGTGGACGTCCGGCAGATCTACGACAAATTCCCTGAGAAAAAG
GGTGGCCTCCGAGAGCTATATGATCGTGGCCCCCCCCATGCCTTCTTCCTGGTCAAGTTCTGGGCGGACCTGAACTGGGGCCCAAGTGGT
GAGGAGGCAGGGGCCGGTGGCAGCATCAGCAGTGGTGGCTTCTACGGAGTGAGCAGCCAGTATGAGAGCCTGGAACACATGACCCTCACC
TGTTCCTCCAAGGTCTGCTCTTTTGGCAAGCAGGTGGTGGAGAAGGTGGAGACGGAACGGGCCCAGCTGGAGGACGGCAGATTTGTGTAC
CGCCTGCTGCGCTCGCCCATGTGCGAGTACCTGGTGAATTTCTTGCACAAGTTGCGGCAGCTGCCTGAGCGATACATGATGAACAGCGTC
CTGGAAAACTTCACCATCCTCCAGGTGGTGACAAACAGAGACACCCAGGAACTGCTGCTCTGCACCGCCTATGTCTTCGAGGTCTCCACC
AGCGAGCGTGGGGCCCAGCATCACATTTACCGCCTGGTCAGGGACTGAAGGGGGACCCCAAAACTGGCTCACCCCCCAGAACACCCTCCT
CCCAGGGAGGGTCCTCCAGCTCACCTCATGCTTCTTATTTGGGGAGAGGGCTGTGATGTAAAGGGGTTGACCTCAGAGGCCTAAGCAACT
GGGGCCATCCCCCCCATTAGAGGGGCCCCCAAAACTTGGTTGGAGAGCTGAACAGGCTGGGACTGAGGAAAGGATAAACCCCGATATTGG
GACCTCACAGTGGGTGTCTGAAAGGACAGATCACTCCGGAGTATCAGGGATTGTGGGGACAGGAGTGAGACAACCCCCCAGGTACAGCAC
TGGCTTTTCTTTTCAGCCCCTGACAGGCCACCCCCACTCCTCTGCATGTCTTGGAGAGCGCTAGTTACACATTGGCTTGTCCCCTTTACT
TTTTCCCAGCCACCCCTCCCCCTGAAATTTCTGCCCCTCTCTACCACCCTCACTCCATGACCTGTGAGATCACAAAGTGAAGATGAACCC
TTTCTGTGCAGGAGCAGAGCCAGGTGGGCCCTGGACATTTTTTTTTTTTTTAATATAACGAGATATTTATAAGTGGGTGCTAGGGTCTTG
ACTTTATCTCCGCTGCACAAGCAGTGTGTTGAACTTTCTAATCTCATCCCTCTCCTAAGTGAGCCCTGAGCTAGACGGTTTCCTTCCTCC

>89927_89927_5_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000421545_TEAD2_chr19_49854622_ENST00000598810_length(amino acids)=645AA_BP=374
MLQLLVLKIEDPGCFWVIIKGCSPFLDHDVDYQKLNSAMNDFYNSTCQDIEIKPLTLEEGQVCVVYCEELKCWCRAIVKSITSSADQYLA
ECFLVDFAKNIPVKSKNIRVVVESFMQLPYRAKKFSLYCTKPVTLHIDFCRDSTDIVPAKKWDNAAIQYFQNLLKATTQVEARLCAVEED
TFEVYLYVTIKDEKVCVNDDLVAKNYACYMSPTKNKNLDYLEKPRLNIKSAPSFNKLNPALTLWPMFLQGKDVQGMEDSHGVNFPAQSLQ
HTWCKGIVGDLRPTATAQDKAVKCNMDSLRDSPKDKSEKKHHCISLKDTNKRVESSVYWPAKRGITIYADPDVPEASALSQKSNEKPLRL
TEKKEYDEKNSCVNVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFV
HISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLT
CSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVST

--------------------------------------------------------------
>89927_89927_6_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000421545_TEAD2_chr19_49854622_ENST00000601519_length(transcript)=2667nt_BP=1121nt
ATGCTCCAGCTCCTGGTGCTGAAGATTGAAGATCCAGGTTGCTTCTGGGTTATTATAAAAGGGTGTAGTCCCTTTTTAGATCATGATGTC
GATTATCAAAAATTAAATAGTGCCATGAATGACTTCTACAACAGCACGTGTCAAGATATAGAAATAAAACCCTTAACATTGGAAGAAGGA
CAGGTGTGTGTGGTCTATTGTGAGGAGCTAAAGTGCTGGTGCAGGGCCATTGTCAAATCAATTACGTCTTCCGCAGACCAGTACCTGGCA
GAATGTTTCCTTGTGGACTTTGCCAAGAACATTCCAGTCAAATCTAAAAACATCCGAGTTGTAGTAGAATCGTTTATGCAGCTTCCCTAT
AGAGCAAAAAAATTCAGCCTGTACTGCACAAAGCCTGTCACATTACACATTGACTTCTGCCGAGACAGTACTGACATTGTACCTGCCAAG
AAGTGGGACAATGCAGCTATTCAGTACTTTCAGAACCTTCTGAAAGCAACTACCCAGGTGGAAGCCAGATTATGTGCTGTGGAAGAAGAT
ACATTTGAGGTTTACCTTTATGTAACTATAAAAGATGAAAAAGTTTGTGTTAATGATGATCTTGTTGCAAAGAACTATGCTTGTTATATG
TCACCTACAAAGAATAAAAACCTTGATTATTTAGAAAAACCAAGATTGAATATAAAATCAGCACCCTCCTTCAATAAACTCAATCCAGCA
CTTACACTCTGGCCAATGTTTTTGCAAGGAAAAGATGTTCAAGGAATGGAAGATTCACATGGTGTAAATTTTCCGGCACAATCTCTGCAA
CATACATGGTGCAAGGGTATTGTCGGTGACCTCAGGCCAACAGCCACAGCACAGGACAAAGCTGTAAAATGTAATATGGATTCATTGAGA
GATTCACCTAAAGACAAATCTGAAAAGAAACACCATTGCATCTCTTTAAAAGATACAAATAAGCGTGTTGAATCCTCAGTGTACTGGCCA
GCAAAAAGAGGCATAACCATATATGCTGATCCAGATGTACCAGAAGCAAGTGCTTTAAGTCAGAAGTCAAATGAGAAACCTCTTAGATTG
ACTGAGAAGAAAGAATATGATGAGAAGAATAGCTGTGTGAATGTGAAGCCATTCTCACAGACACCGTTCACCTTGTCACTGACTCCCCCA
TCTACTGACCTCCCAGGGTACGAGCCCCCCCAAGCCCTCTCACCCCTGCCCCCACCTACCCCATCGCCCCCAGCCTGGCAGGCTCGGGGC
CTGGGCACCGCCCGGTTGCAGCTGGTAGAGTTCTCAGCCTTCGTGGAACCGCCAGATGCAGTTGATTCTTACCAGAGGCACCTGTTCGTG
CACATCAGCCAGCACTGCCCCAGCCCCGGAGCGCCGCCGCTCGAGAGTGTGGACGTCCGGCAGATCTACGACAAATTCCCTGAGAAAAAG
GGTGGCCTCCGAGAGCTATATGATCGTGGCCCCCCCCATGCCTTCTTCCTGGTCAAGTTCTGGGCGGACCTGAACTGGGGCCCAAGTGGT
GAGGAGGCAGGGGCCGGTGGCAGCATCAGCAGTGGTGGCTTCTACGGAGTGAGCAGCCAGTATGAGAGCCTGGAACACATGACCCTCACC
TGTTCCTCCAAGGTCTGCTCTTTTGGCAAGCAGGTGGTGGAGAAGGTGGAGACGGAACGGGCCCAGCTGGAGGACGGCAGATTTGTGTAC
CGCCTGCTGCGCTCGCCCATGTGCGAGTACCTGGTGAATTTCTTGCACAAGTTGCGGCAGCTGCCTGAGCGATACATGATGAACAGCGTC
CTGGAAAACTTCACCATCCTCCAGGTGGTGACAAACAGAGACACCCAGGAACTGCTGCTCTGCACCGCCTATGTCTTCGAGGTCTCCACC
AGCGAGCGTGGGGCCCAGCATCACATTTACCGCCTGGTCAGGGACTGAAGGGGGACCCCAAAACTGGCTCACCCCCCAGAACACCCTCCT
CCCAGGGAGGGTCCTCCAGCTCACCTCATGCTTCTTATTTGGGGAGAGGGCTGTGATGTAAAGGGGTTGACCTCAGAGGCCTAAGCAACT
GGGGCCATCCCCCCCATTAGAGGGGCCCCCAAAACTTGGTTGGAGAGCTGAACAGGCTGGGACTGAGGAAAGGATAAACCCCGATATTGG
GACCTCACAGTGGGTGTCTGAAAGGACAGATCACTCCGGAGTATCAGGGATTGTGGGGACAGGAGTGAGACAACCCCCCAGGTACAGCAC
TGGCTTTTCTTTTCAGCCCCTGACAGGCCACCCCCACTCCTCTGCATGTCTTGGAGAGCGCTAGTTACACATTGGCTTGTCCCCTTTACT
TTTTCCCAGCCACCCCTCCCCCTGAAATTTCTGCCCCTCTCTACCACCCTCACTCCATGACCTGTGAGATCACAAAGTGAAGATGAACCC
TTTCTGTGCAGGAGCAGAGCCAGGTGGGCCCTGGACATTTTTTTTTTTTTTAATATAACGAGATATTTATAAGTGGGTGCTAGGGTCTTG
ACTTTATCTCCGCTGCACAAGCAGTGTGTTGAACTTTCTAATCTCATCCCTCTCCTAAGTGAGCCCTGAGCTAGACGGTTTCCTTCCTCC

>89927_89927_6_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000421545_TEAD2_chr19_49854622_ENST00000601519_length(amino acids)=645AA_BP=374
MLQLLVLKIEDPGCFWVIIKGCSPFLDHDVDYQKLNSAMNDFYNSTCQDIEIKPLTLEEGQVCVVYCEELKCWCRAIVKSITSSADQYLA
ECFLVDFAKNIPVKSKNIRVVVESFMQLPYRAKKFSLYCTKPVTLHIDFCRDSTDIVPAKKWDNAAIQYFQNLLKATTQVEARLCAVEED
TFEVYLYVTIKDEKVCVNDDLVAKNYACYMSPTKNKNLDYLEKPRLNIKSAPSFNKLNPALTLWPMFLQGKDVQGMEDSHGVNFPAQSLQ
HTWCKGIVGDLRPTATAQDKAVKCNMDSLRDSPKDKSEKKHHCISLKDTNKRVESSVYWPAKRGITIYADPDVPEASALSQKSNEKPLRL
TEKKEYDEKNSCVNVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFV
HISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLT
CSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVST

--------------------------------------------------------------
>89927_89927_7_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000444215_TEAD2_chr19_49854622_ENST00000311227_length(transcript)=2987nt_BP=1441nt
CGACGCCTCAAGGCCTGCTCAGCGTGCGCGGGCATCCGGTGGGTGCGGGAGGCCCGAGGCCAGGCAGGCAGGGATCCCGCAGCGAGGGGC
TGGTTACTGCCAGGACGGAGCGCATTGCCTCGAGCCGACCCCGGGGTCCGCGAGGGCTCCTGGGGACGAGGAGTGTGGGGCACCTGCCGC
GGGGGGCCCAGGCGCTAAAGGTGGAGGGAAGGAACGCACTCGCGGCGGGGGCCTGGCCGGGGCGGACGCAGCCAGCCTCACCCGCGACGG
TAGGGGACTTCCAGGGCGAGGGGGCCCATCTGCCCTCGGGCGCCAGGAGGATGCTCCAGCTCCTGGTGCTGAAGATTGAAGATCCAGGTT
GCTTCTGGGTTATTATAAAAGGGTGTAGTCCCTTTTTAGATCATGATGTCGATTATCAAAAATTAAATAGTGCCATGAATGACTTCTACA
ACAGCACGTGTCAAGATATAGAAATAAAACCCTTAACATTGGAAGAAGGACAGGTGTGTGTGGTCTATTGTGAGGAGCTAAAGTGCTGGT
GCAGGGCCATTGTCAAATCAATTACGTCTTCCGCAGACCAGTACCTGGCAGAATGTTTCCTTGTGGACTTTGCCAAGAACATTCCAGTCA
AATCTAAAAACATCCGAGTTGTAGTAGAATCGTTTATGCAGCTTCCCTATAGAGCAAAAAAATTCAGCCTGTACTGCACAAAGCCTGTCA
CATTACACATTGACTTCTGCCGAGACAGTACTGACATTGTACCTGCCAAGAAGTGGGACAATGCAGCTATTCAGTACTTTCAGAACCTTC
TGAAAGCAACTACCCAGGTGGAAGCCAGATTATGTGCTGTGGAAGAAGATACATTTGAGGTTTACCTTTATGTAACTATAAAAGATGAAA
AAGTTTGTGTTAATGATGATCTTGTTGCAAAGAACTATGCTTGTTATATGTCACCTACAAAGAATAAAAACCTTGATTATTTAGAAAAAC
CAAGATTGAATATAAAATCAGCACCCTCCTTCAATAAACTCAATCCAGCACTTACACTCTGGCCAATGTTTTTGCAAGGAAAAGATGTTC
AAGGAATGGAAGATTCACATGGTGTAAATTTTCCGGCACAATCTCTGCAACATACATGGTGCAAGGGTATTGTCGGTGACCTCAGGCCAA
CAGCCACAGCACAGGACAAAGCTGTAAAATGTAATATGGATTCATTGAGAGATTCACCTAAAGACAAATCTGAAAAGAAACACCATTGCA
TCTCTTTAAAAGATACAAATAAGCGTGTTGAATCCTCAGTGTACTGGCCAGCAAAAAGAGGCATAACCATATATGCTGATCCAGATGTAC
CAGAAGCAAGTGCTTTAAGTCAGAAGTCAAATGAGAAACCTCTTAGATTGACTGAGAAGAAAGAATATGATGAGAAGAATAGCTGTGTGA
ATGTGAAGCCATTCTCACAGACACCGTTCACCTTGTCACTGACTCCCCCATCTACTGACCTCCCAGGGTACGAGCCCCCCCAAGCCCTCT
CACCCCTGCCCCCACCTACCCCATCGCCCCCAGCCTGGCAGGCTCGGGGCCTGGGCACCGCCCGGTTGCAGCTGGTAGAGTTCTCAGCCT
TCGTGGAACCGCCAGATGCAGTTGATTCTTACCAGAGGCACCTGTTCGTGCACATCAGCCAGCACTGCCCCAGCCCCGGAGCGCCGCCGC
TCGAGAGTGTGGACGTCCGGCAGATCTACGACAAATTCCCTGAGAAAAAGGGTGGCCTCCGAGAGCTATATGATCGTGGCCCCCCCCATG
CCTTCTTCCTGGTCAAGTTCTGGGCGGACCTGAACTGGGGCCCAAGTGGTGAGGAGGCAGGGGCCGGTGGCAGCATCAGCAGTGGTGGCT
TCTACGGAGTGAGCAGCCAGTATGAGAGCCTGGAACACATGACCCTCACCTGTTCCTCCAAGGTCTGCTCTTTTGGCAAGCAGGTGGTGG
AGAAGGTGGAGACGGAACGGGCCCAGCTGGAGGACGGCAGATTTGTGTACCGCCTGCTGCGCTCGCCCATGTGCGAGTACCTGGTGAATT
TCTTGCACAAGTTGCGGCAGCTGCCTGAGCGATACATGATGAACAGCGTCCTGGAAAACTTCACCATCCTCCAGGTGGTGACAAACAGAG
ACACCCAGGAACTGCTGCTCTGCACCGCCTATGTCTTCGAGGTCTCCACCAGCGAGCGTGGGGCCCAGCATCACATTTACCGCCTGGTCA
GGGACTGAAGGGGGACCCCAAAACTGGCTCACCCCCCAGAACACCCTCCTCCCAGGGAGGGTCCTCCAGCTCACCTCATGCTTCTTATTT
GGGGAGAGGGCTGTGATGTAAAGGGGTTGACCTCAGAGGCCTAAGCAACTGGGGCCATCCCCCCCATTAGAGGGGCCCCCAAAACTTGGT
TGGAGAGCTGAACAGGCTGGGACTGAGGAAAGGATAAACCCCGATATTGGGACCTCACAGTGGGTGTCTGAAAGGACAGATCACTCCGGA
GTATCAGGGATTGTGGGGACAGGAGTGAGACAACCCCCCAGGTACAGCACTGGCTTTTCTTTTCAGCCCCTGACAGGCCACCCCCACTCC
TCTGCATGTCTTGGAGAGCGCTAGTTACACATTGGCTTGTCCCCTTTACTTTTTCCCAGCCACCCCTCCCCCTGAAATTTCTGCCCCTCT
CTACCACCCTCACTCCATGACCTGTGAGATCACAAAGTGAAGATGAACCCTTTCTGTGCAGGAGCAGAGCCAGGTGGGCCCTGGACATTT
TTTTTTTTTTTAATATAACGAGATATTTATAAGTGGGTGCTAGGGTCTTGACTTTATCTCCGCTGCACAAGCAGTGTGTTGAACTTTCTA
ATCTCATCCCTCTCCTAAGTGAGCCCTGAGCTAGACGGTTTCCTTCCTCCCCTCTCAAAGTTTGTTTGTTTGTGTTCTGACAGAGGATAA

>89927_89927_7_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000444215_TEAD2_chr19_49854622_ENST00000311227_length(amino acids)=747AA_BP=476
MLSVRGHPVGAGGPRPGRQGSRSEGLVTARTERIASSRPRGPRGLLGTRSVGHLPRGAQALKVEGRNALAAGAWPGRTQPASPATVGDFQ
GEGAHLPSGARRMLQLLVLKIEDPGCFWVIIKGCSPFLDHDVDYQKLNSAMNDFYNSTCQDIEIKPLTLEEGQVCVVYCEELKCWCRAIV
KSITSSADQYLAECFLVDFAKNIPVKSKNIRVVVESFMQLPYRAKKFSLYCTKPVTLHIDFCRDSTDIVPAKKWDNAAIQYFQNLLKATT
QVEARLCAVEEDTFEVYLYVTIKDEKVCVNDDLVAKNYACYMSPTKNKNLDYLEKPRLNIKSAPSFNKLNPALTLWPMFLQGKDVQGMED
SHGVNFPAQSLQHTWCKGIVGDLRPTATAQDKAVKCNMDSLRDSPKDKSEKKHHCISLKDTNKRVESSVYWPAKRGITIYADPDVPEASA
LSQKSNEKPLRLTEKKEYDEKNSCVNVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPP
DAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVS
SQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQEL

--------------------------------------------------------------
>89927_89927_8_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000444215_TEAD2_chr19_49854622_ENST00000377214_length(transcript)=2982nt_BP=1441nt
CGACGCCTCAAGGCCTGCTCAGCGTGCGCGGGCATCCGGTGGGTGCGGGAGGCCCGAGGCCAGGCAGGCAGGGATCCCGCAGCGAGGGGC
TGGTTACTGCCAGGACGGAGCGCATTGCCTCGAGCCGACCCCGGGGTCCGCGAGGGCTCCTGGGGACGAGGAGTGTGGGGCACCTGCCGC
GGGGGGCCCAGGCGCTAAAGGTGGAGGGAAGGAACGCACTCGCGGCGGGGGCCTGGCCGGGGCGGACGCAGCCAGCCTCACCCGCGACGG
TAGGGGACTTCCAGGGCGAGGGGGCCCATCTGCCCTCGGGCGCCAGGAGGATGCTCCAGCTCCTGGTGCTGAAGATTGAAGATCCAGGTT
GCTTCTGGGTTATTATAAAAGGGTGTAGTCCCTTTTTAGATCATGATGTCGATTATCAAAAATTAAATAGTGCCATGAATGACTTCTACA
ACAGCACGTGTCAAGATATAGAAATAAAACCCTTAACATTGGAAGAAGGACAGGTGTGTGTGGTCTATTGTGAGGAGCTAAAGTGCTGGT
GCAGGGCCATTGTCAAATCAATTACGTCTTCCGCAGACCAGTACCTGGCAGAATGTTTCCTTGTGGACTTTGCCAAGAACATTCCAGTCA
AATCTAAAAACATCCGAGTTGTAGTAGAATCGTTTATGCAGCTTCCCTATAGAGCAAAAAAATTCAGCCTGTACTGCACAAAGCCTGTCA
CATTACACATTGACTTCTGCCGAGACAGTACTGACATTGTACCTGCCAAGAAGTGGGACAATGCAGCTATTCAGTACTTTCAGAACCTTC
TGAAAGCAACTACCCAGGTGGAAGCCAGATTATGTGCTGTGGAAGAAGATACATTTGAGGTTTACCTTTATGTAACTATAAAAGATGAAA
AAGTTTGTGTTAATGATGATCTTGTTGCAAAGAACTATGCTTGTTATATGTCACCTACAAAGAATAAAAACCTTGATTATTTAGAAAAAC
CAAGATTGAATATAAAATCAGCACCCTCCTTCAATAAACTCAATCCAGCACTTACACTCTGGCCAATGTTTTTGCAAGGAAAAGATGTTC
AAGGAATGGAAGATTCACATGGTGTAAATTTTCCGGCACAATCTCTGCAACATACATGGTGCAAGGGTATTGTCGGTGACCTCAGGCCAA
CAGCCACAGCACAGGACAAAGCTGTAAAATGTAATATGGATTCATTGAGAGATTCACCTAAAGACAAATCTGAAAAGAAACACCATTGCA
TCTCTTTAAAAGATACAAATAAGCGTGTTGAATCCTCAGTGTACTGGCCAGCAAAAAGAGGCATAACCATATATGCTGATCCAGATGTAC
CAGAAGCAAGTGCTTTAAGTCAGAAGTCAAATGAGAAACCTCTTAGATTGACTGAGAAGAAAGAATATGATGAGAAGAATAGCTGTGTGA
ATGTGAAGCCATTCTCACAGACACCGTTCACCTTGTCACTGACTCCCCCATCTACTGACCTCCCAGGGTACGAGCCCCCCCAAGCCCTCT
CACCCCTGCCCCCACCTACCCCATCGCCCCCAGCCTGGCAGGCTCGGGGCCTGGGCACCGCCCGGTTGCAGCTGGTAGAGTTCTCAGCCT
TCGTGGAACCGCCAGATGCAGTTGATTCTTACCAGAGGCACCTGTTCGTGCACATCAGCCAGCACTGCCCCAGCCCCGGAGCGCCGCCGC
TCGAGAGTGTGGACGTCCGGCAGATCTACGACAAATTCCCTGAGAAAAAGGGTGGCCTCCGAGAGCTATATGATCGTGGCCCCCCCCATG
CCTTCTTCCTGGTCAAGTTCTGGGCGGACCTGAACTGGGGCCCAAGTGGTGAGGAGGCAGGGGCCGGTGGCAGCATCAGCAGTGGTGGCT
TCTACGGAGTGAGCAGCCAGTATGAGAGCCTGGAACACATGACCCTCACCTGTTCCTCCAAGGTCTGCTCTTTTGGCAAGCAGGTGGTGG
AGAAGGTGGAGACGGAACGGGCCCAGCTGGAGGACGGCAGATTTGTGTACCGCCTGCTGCGCTCGCCCATGTGCGAGTACCTGGTGAATT
TCTTGCACAAGTTGCGGCAGCTGCCTGAGCGATACATGATGAACAGCGTCCTGGAAAACTTCACCATCCTCCAGGTGGTGACAAACAGAG
ACACCCAGGAACTGCTGCTCTGCACCGCCTATGTCTTCGAGGTCTCCACCAGCGAGCGTGGGGCCCAGCATCACATTTACCGCCTGGTCA
GGGACTGAAGGGGGACCCCAAAACTGGCTCACCCCCCAGAACACCCTCCTCCCAGGGAGGGTCCTCCAGCTCACCTCATGCTTCTTATTT
GGGGAGAGGGCTGTGATGTAAAGGGGTTGACCTCAGAGGCCTAAGCAACTGGGGCCATCCCCCCCATTAGAGGGGCCCCCAAAACTTGGT
TGGAGAGCTGAACAGGCTGGGACTGAGGAAAGGATAAACCCCGATATTGGGACCTCACAGTGGGTGTCTGAAAGGACAGATCACTCCGGA
GTATCAGGGATTGTGGGGACAGGAGTGAGACAACCCCCCAGGTACAGCACTGGCTTTTCTTTTCAGCCCCTGACAGGCCACCCCCACTCC
TCTGCATGTCTTGGAGAGCGCTAGTTACACATTGGCTTGTCCCCTTTACTTTTTCCCAGCCACCCCTCCCCCTGAAATTTCTGCCCCTCT
CTACCACCCTCACTCCATGACCTGTGAGATCACAAAGTGAAGATGAACCCTTTCTGTGCAGGAGCAGAGCCAGGTGGGCCCTGGACATTT
TTTTTTTTTTTAATATAACGAGATATTTATAAGTGGGTGCTAGGGTCTTGACTTTATCTCCGCTGCACAAGCAGTGTGTTGAACTTTCTA
ATCTCATCCCTCTCCTAAGTGAGCCCTGAGCTAGACGGTTTCCTTCCTCCCCTCTCAAAGTTTGTTTGTTTGTGTTCTGACAGAGGATAA

>89927_89927_8_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000444215_TEAD2_chr19_49854622_ENST00000377214_length(amino acids)=747AA_BP=476
MLSVRGHPVGAGGPRPGRQGSRSEGLVTARTERIASSRPRGPRGLLGTRSVGHLPRGAQALKVEGRNALAAGAWPGRTQPASPATVGDFQ
GEGAHLPSGARRMLQLLVLKIEDPGCFWVIIKGCSPFLDHDVDYQKLNSAMNDFYNSTCQDIEIKPLTLEEGQVCVVYCEELKCWCRAIV
KSITSSADQYLAECFLVDFAKNIPVKSKNIRVVVESFMQLPYRAKKFSLYCTKPVTLHIDFCRDSTDIVPAKKWDNAAIQYFQNLLKATT
QVEARLCAVEEDTFEVYLYVTIKDEKVCVNDDLVAKNYACYMSPTKNKNLDYLEKPRLNIKSAPSFNKLNPALTLWPMFLQGKDVQGMED
SHGVNFPAQSLQHTWCKGIVGDLRPTATAQDKAVKCNMDSLRDSPKDKSEKKHHCISLKDTNKRVESSVYWPAKRGITIYADPDVPEASA
LSQKSNEKPLRLTEKKEYDEKNSCVNVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPP
DAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVS
SQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQEL

--------------------------------------------------------------
>89927_89927_9_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000444215_TEAD2_chr19_49854622_ENST00000539846_length(transcript)=2500nt_BP=1441nt
CGACGCCTCAAGGCCTGCTCAGCGTGCGCGGGCATCCGGTGGGTGCGGGAGGCCCGAGGCCAGGCAGGCAGGGATCCCGCAGCGAGGGGC
TGGTTACTGCCAGGACGGAGCGCATTGCCTCGAGCCGACCCCGGGGTCCGCGAGGGCTCCTGGGGACGAGGAGTGTGGGGCACCTGCCGC
GGGGGGCCCAGGCGCTAAAGGTGGAGGGAAGGAACGCACTCGCGGCGGGGGCCTGGCCGGGGCGGACGCAGCCAGCCTCACCCGCGACGG
TAGGGGACTTCCAGGGCGAGGGGGCCCATCTGCCCTCGGGCGCCAGGAGGATGCTCCAGCTCCTGGTGCTGAAGATTGAAGATCCAGGTT
GCTTCTGGGTTATTATAAAAGGGTGTAGTCCCTTTTTAGATCATGATGTCGATTATCAAAAATTAAATAGTGCCATGAATGACTTCTACA
ACAGCACGTGTCAAGATATAGAAATAAAACCCTTAACATTGGAAGAAGGACAGGTGTGTGTGGTCTATTGTGAGGAGCTAAAGTGCTGGT
GCAGGGCCATTGTCAAATCAATTACGTCTTCCGCAGACCAGTACCTGGCAGAATGTTTCCTTGTGGACTTTGCCAAGAACATTCCAGTCA
AATCTAAAAACATCCGAGTTGTAGTAGAATCGTTTATGCAGCTTCCCTATAGAGCAAAAAAATTCAGCCTGTACTGCACAAAGCCTGTCA
CATTACACATTGACTTCTGCCGAGACAGTACTGACATTGTACCTGCCAAGAAGTGGGACAATGCAGCTATTCAGTACTTTCAGAACCTTC
TGAAAGCAACTACCCAGGTGGAAGCCAGATTATGTGCTGTGGAAGAAGATACATTTGAGGTTTACCTTTATGTAACTATAAAAGATGAAA
AAGTTTGTGTTAATGATGATCTTGTTGCAAAGAACTATGCTTGTTATATGTCACCTACAAAGAATAAAAACCTTGATTATTTAGAAAAAC
CAAGATTGAATATAAAATCAGCACCCTCCTTCAATAAACTCAATCCAGCACTTACACTCTGGCCAATGTTTTTGCAAGGAAAAGATGTTC
AAGGAATGGAAGATTCACATGGTGTAAATTTTCCGGCACAATCTCTGCAACATACATGGTGCAAGGGTATTGTCGGTGACCTCAGGCCAA
CAGCCACAGCACAGGACAAAGCTGTAAAATGTAATATGGATTCATTGAGAGATTCACCTAAAGACAAATCTGAAAAGAAACACCATTGCA
TCTCTTTAAAAGATACAAATAAGCGTGTTGAATCCTCAGTGTACTGGCCAGCAAAAAGAGGCATAACCATATATGCTGATCCAGATGTAC
CAGAAGCAAGTGCTTTAAGTCAGAAGTCAAATGAGAAACCTCTTAGATTGACTGAGAAGAAAGAATATGATGAGAAGAATAGCTGTGTGA
ATGTGAAGCCATTCTCACAGACACCGTTCACCTTGTCACTGACTCCCCCATCTACTGACCTCCCAGGGTACGAGCCCCCCCAAGCCCTCT
CACCCCTGCCCCCACCTACCCCATCGCCCCCAGCCTGGCAGGCTCGGGGCCTGGGCACCGCCCGGTTGCAGCTGGTAGAGTTCTCAGCCT
TCGTGGAACCGCCAGATGCAGTTGATTCTTACCAGAGGCACCTGTTCGTGCACATCAGCCAGCACTGCCCCAGCCCCGGAGCGCCGCCGC
TCGAGAGTGTGGACGTCCGGCAGATCTACGACAAATTCCCTGAGAAAAAGGGTGGCCTCCGAGAGCTATATGATCGTGGCCCCCCCCATG
CCTTCTTCCTGGTCAAGTTCTGGGCGGACCTGAACTGGGGCCCAAGTGGTGAGGAGGCAGGGGCCGGTGGCAGCATCAGCAGTGGTGGCT
TCTACGGAGTGAGCAGCCAGTATGAGAGCCTGGAACACATGACCCTCACCTGTTCCTCCAAGGTCTGCTCTTTTGGCAAGCAGGTGGTGG
AGAAGGTGGAGACGGAACGGGCCCAGCTGGAGGACGGCAGATTTGTGTACCGCCTGCTGCGCTCGCCCATGTGCGAGTACCTGGTGAATT
TCTTGCACAAGTTGCGGCAGCTGCCTGAGCGATACATGATGAACAGCGTCCTGGAAAACTTCACCATCCTCCAGGTGGTGACAAACAGAG
ACACCCAGGAACTGCTGCTCTGCACCGCCTATGTCTTCGAGGTCTCCACCAGCGAGCGTGGGGCCCAGCATCACATTTACCGCCTGGTCA
GGGACTGAAGGGGGACCCCAAAACTGGCTCACCCCCCAGAACACCCTCCTCCCAGGGAGGGTCCTCCAGCTCACCTCATGCTTCTTATTT
GGGGAGAGGGCTGTGATGTAAAGGGGTTGACCTCAGAGGCCTAAGCAACTGGGGCCATCCCCCCCATTAGAGGGGCCCCCAAAACTTGGT

>89927_89927_9_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000444215_TEAD2_chr19_49854622_ENST00000539846_length(amino acids)=747AA_BP=476
MLSVRGHPVGAGGPRPGRQGSRSEGLVTARTERIASSRPRGPRGLLGTRSVGHLPRGAQALKVEGRNALAAGAWPGRTQPASPATVGDFQ
GEGAHLPSGARRMLQLLVLKIEDPGCFWVIIKGCSPFLDHDVDYQKLNSAMNDFYNSTCQDIEIKPLTLEEGQVCVVYCEELKCWCRAIV
KSITSSADQYLAECFLVDFAKNIPVKSKNIRVVVESFMQLPYRAKKFSLYCTKPVTLHIDFCRDSTDIVPAKKWDNAAIQYFQNLLKATT
QVEARLCAVEEDTFEVYLYVTIKDEKVCVNDDLVAKNYACYMSPTKNKNLDYLEKPRLNIKSAPSFNKLNPALTLWPMFLQGKDVQGMED
SHGVNFPAQSLQHTWCKGIVGDLRPTATAQDKAVKCNMDSLRDSPKDKSEKKHHCISLKDTNKRVESSVYWPAKRGITIYADPDVPEASA
LSQKSNEKPLRLTEKKEYDEKNSCVNVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPP
DAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVS
SQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQEL

--------------------------------------------------------------
>89927_89927_10_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000444215_TEAD2_chr19_49854622_ENST00000593945_length(transcript)=2987nt_BP=1441nt
CGACGCCTCAAGGCCTGCTCAGCGTGCGCGGGCATCCGGTGGGTGCGGGAGGCCCGAGGCCAGGCAGGCAGGGATCCCGCAGCGAGGGGC
TGGTTACTGCCAGGACGGAGCGCATTGCCTCGAGCCGACCCCGGGGTCCGCGAGGGCTCCTGGGGACGAGGAGTGTGGGGCACCTGCCGC
GGGGGGCCCAGGCGCTAAAGGTGGAGGGAAGGAACGCACTCGCGGCGGGGGCCTGGCCGGGGCGGACGCAGCCAGCCTCACCCGCGACGG
TAGGGGACTTCCAGGGCGAGGGGGCCCATCTGCCCTCGGGCGCCAGGAGGATGCTCCAGCTCCTGGTGCTGAAGATTGAAGATCCAGGTT
GCTTCTGGGTTATTATAAAAGGGTGTAGTCCCTTTTTAGATCATGATGTCGATTATCAAAAATTAAATAGTGCCATGAATGACTTCTACA
ACAGCACGTGTCAAGATATAGAAATAAAACCCTTAACATTGGAAGAAGGACAGGTGTGTGTGGTCTATTGTGAGGAGCTAAAGTGCTGGT
GCAGGGCCATTGTCAAATCAATTACGTCTTCCGCAGACCAGTACCTGGCAGAATGTTTCCTTGTGGACTTTGCCAAGAACATTCCAGTCA
AATCTAAAAACATCCGAGTTGTAGTAGAATCGTTTATGCAGCTTCCCTATAGAGCAAAAAAATTCAGCCTGTACTGCACAAAGCCTGTCA
CATTACACATTGACTTCTGCCGAGACAGTACTGACATTGTACCTGCCAAGAAGTGGGACAATGCAGCTATTCAGTACTTTCAGAACCTTC
TGAAAGCAACTACCCAGGTGGAAGCCAGATTATGTGCTGTGGAAGAAGATACATTTGAGGTTTACCTTTATGTAACTATAAAAGATGAAA
AAGTTTGTGTTAATGATGATCTTGTTGCAAAGAACTATGCTTGTTATATGTCACCTACAAAGAATAAAAACCTTGATTATTTAGAAAAAC
CAAGATTGAATATAAAATCAGCACCCTCCTTCAATAAACTCAATCCAGCACTTACACTCTGGCCAATGTTTTTGCAAGGAAAAGATGTTC
AAGGAATGGAAGATTCACATGGTGTAAATTTTCCGGCACAATCTCTGCAACATACATGGTGCAAGGGTATTGTCGGTGACCTCAGGCCAA
CAGCCACAGCACAGGACAAAGCTGTAAAATGTAATATGGATTCATTGAGAGATTCACCTAAAGACAAATCTGAAAAGAAACACCATTGCA
TCTCTTTAAAAGATACAAATAAGCGTGTTGAATCCTCAGTGTACTGGCCAGCAAAAAGAGGCATAACCATATATGCTGATCCAGATGTAC
CAGAAGCAAGTGCTTTAAGTCAGAAGTCAAATGAGAAACCTCTTAGATTGACTGAGAAGAAAGAATATGATGAGAAGAATAGCTGTGTGA
ATGTGAAGCCATTCTCACAGACACCGTTCACCTTGTCACTGACTCCCCCATCTACTGACCTCCCAGGGTACGAGCCCCCCCAAGCCCTCT
CACCCCTGCCCCCACCTACCCCATCGCCCCCAGCCTGGCAGGCTCGGGGCCTGGGCACCGCCCGGTTGCAGCTGGTAGAGTTCTCAGCCT
TCGTGGAACCGCCAGATGCAGTTGATTCTTACCAGAGGCACCTGTTCGTGCACATCAGCCAGCACTGCCCCAGCCCCGGAGCGCCGCCGC
TCGAGAGTGTGGACGTCCGGCAGATCTACGACAAATTCCCTGAGAAAAAGGGTGGCCTCCGAGAGCTATATGATCGTGGCCCCCCCCATG
CCTTCTTCCTGGTCAAGTTCTGGGCGGACCTGAACTGGGGCCCAAGTGGTGAGGAGGCAGGGGCCGGTGGCAGCATCAGCAGTGGTGGCT
TCTACGGAGTGAGCAGCCAGTATGAGAGCCTGGAACACATGACCCTCACCTGTTCCTCCAAGGTCTGCTCTTTTGGCAAGCAGGTGGTGG
AGAAGGTGGAGACGGAACGGGCCCAGCTGGAGGACGGCAGATTTGTGTACCGCCTGCTGCGCTCGCCCATGTGCGAGTACCTGGTGAATT
TCTTGCACAAGTTGCGGCAGCTGCCTGAGCGATACATGATGAACAGCGTCCTGGAAAACTTCACCATCCTCCAGGTGGTGACAAACAGAG
ACACCCAGGAACTGCTGCTCTGCACCGCCTATGTCTTCGAGGTCTCCACCAGCGAGCGTGGGGCCCAGCATCACATTTACCGCCTGGTCA
GGGACTGAAGGGGGACCCCAAAACTGGCTCACCCCCCAGAACACCCTCCTCCCAGGGAGGGTCCTCCAGCTCACCTCATGCTTCTTATTT
GGGGAGAGGGCTGTGATGTAAAGGGGTTGACCTCAGAGGCCTAAGCAACTGGGGCCATCCCCCCCATTAGAGGGGCCCCCAAAACTTGGT
TGGAGAGCTGAACAGGCTGGGACTGAGGAAAGGATAAACCCCGATATTGGGACCTCACAGTGGGTGTCTGAAAGGACAGATCACTCCGGA
GTATCAGGGATTGTGGGGACAGGAGTGAGACAACCCCCCAGGTACAGCACTGGCTTTTCTTTTCAGCCCCTGACAGGCCACCCCCACTCC
TCTGCATGTCTTGGAGAGCGCTAGTTACACATTGGCTTGTCCCCTTTACTTTTTCCCAGCCACCCCTCCCCCTGAAATTTCTGCCCCTCT
CTACCACCCTCACTCCATGACCTGTGAGATCACAAAGTGAAGATGAACCCTTTCTGTGCAGGAGCAGAGCCAGGTGGGCCCTGGACATTT
TTTTTTTTTTTAATATAACGAGATATTTATAAGTGGGTGCTAGGGTCTTGACTTTATCTCCGCTGCACAAGCAGTGTGTTGAACTTTCTA
ATCTCATCCCTCTCCTAAGTGAGCCCTGAGCTAGACGGTTTCCTTCCTCCCCTCTCAAAGTTTGTTTGTTTGTGTTCTGACAGAGGATAA

>89927_89927_10_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000444215_TEAD2_chr19_49854622_ENST00000593945_length(amino acids)=747AA_BP=476
MLSVRGHPVGAGGPRPGRQGSRSEGLVTARTERIASSRPRGPRGLLGTRSVGHLPRGAQALKVEGRNALAAGAWPGRTQPASPATVGDFQ
GEGAHLPSGARRMLQLLVLKIEDPGCFWVIIKGCSPFLDHDVDYQKLNSAMNDFYNSTCQDIEIKPLTLEEGQVCVVYCEELKCWCRAIV
KSITSSADQYLAECFLVDFAKNIPVKSKNIRVVVESFMQLPYRAKKFSLYCTKPVTLHIDFCRDSTDIVPAKKWDNAAIQYFQNLLKATT
QVEARLCAVEEDTFEVYLYVTIKDEKVCVNDDLVAKNYACYMSPTKNKNLDYLEKPRLNIKSAPSFNKLNPALTLWPMFLQGKDVQGMED
SHGVNFPAQSLQHTWCKGIVGDLRPTATAQDKAVKCNMDSLRDSPKDKSEKKHHCISLKDTNKRVESSVYWPAKRGITIYADPDVPEASA
LSQKSNEKPLRLTEKKEYDEKNSCVNVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPP
DAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVS
SQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQEL

--------------------------------------------------------------
>89927_89927_11_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000444215_TEAD2_chr19_49854622_ENST00000598810_length(transcript)=2987nt_BP=1441nt
CGACGCCTCAAGGCCTGCTCAGCGTGCGCGGGCATCCGGTGGGTGCGGGAGGCCCGAGGCCAGGCAGGCAGGGATCCCGCAGCGAGGGGC
TGGTTACTGCCAGGACGGAGCGCATTGCCTCGAGCCGACCCCGGGGTCCGCGAGGGCTCCTGGGGACGAGGAGTGTGGGGCACCTGCCGC
GGGGGGCCCAGGCGCTAAAGGTGGAGGGAAGGAACGCACTCGCGGCGGGGGCCTGGCCGGGGCGGACGCAGCCAGCCTCACCCGCGACGG
TAGGGGACTTCCAGGGCGAGGGGGCCCATCTGCCCTCGGGCGCCAGGAGGATGCTCCAGCTCCTGGTGCTGAAGATTGAAGATCCAGGTT
GCTTCTGGGTTATTATAAAAGGGTGTAGTCCCTTTTTAGATCATGATGTCGATTATCAAAAATTAAATAGTGCCATGAATGACTTCTACA
ACAGCACGTGTCAAGATATAGAAATAAAACCCTTAACATTGGAAGAAGGACAGGTGTGTGTGGTCTATTGTGAGGAGCTAAAGTGCTGGT
GCAGGGCCATTGTCAAATCAATTACGTCTTCCGCAGACCAGTACCTGGCAGAATGTTTCCTTGTGGACTTTGCCAAGAACATTCCAGTCA
AATCTAAAAACATCCGAGTTGTAGTAGAATCGTTTATGCAGCTTCCCTATAGAGCAAAAAAATTCAGCCTGTACTGCACAAAGCCTGTCA
CATTACACATTGACTTCTGCCGAGACAGTACTGACATTGTACCTGCCAAGAAGTGGGACAATGCAGCTATTCAGTACTTTCAGAACCTTC
TGAAAGCAACTACCCAGGTGGAAGCCAGATTATGTGCTGTGGAAGAAGATACATTTGAGGTTTACCTTTATGTAACTATAAAAGATGAAA
AAGTTTGTGTTAATGATGATCTTGTTGCAAAGAACTATGCTTGTTATATGTCACCTACAAAGAATAAAAACCTTGATTATTTAGAAAAAC
CAAGATTGAATATAAAATCAGCACCCTCCTTCAATAAACTCAATCCAGCACTTACACTCTGGCCAATGTTTTTGCAAGGAAAAGATGTTC
AAGGAATGGAAGATTCACATGGTGTAAATTTTCCGGCACAATCTCTGCAACATACATGGTGCAAGGGTATTGTCGGTGACCTCAGGCCAA
CAGCCACAGCACAGGACAAAGCTGTAAAATGTAATATGGATTCATTGAGAGATTCACCTAAAGACAAATCTGAAAAGAAACACCATTGCA
TCTCTTTAAAAGATACAAATAAGCGTGTTGAATCCTCAGTGTACTGGCCAGCAAAAAGAGGCATAACCATATATGCTGATCCAGATGTAC
CAGAAGCAAGTGCTTTAAGTCAGAAGTCAAATGAGAAACCTCTTAGATTGACTGAGAAGAAAGAATATGATGAGAAGAATAGCTGTGTGA
ATGTGAAGCCATTCTCACAGACACCGTTCACCTTGTCACTGACTCCCCCATCTACTGACCTCCCAGGGTACGAGCCCCCCCAAGCCCTCT
CACCCCTGCCCCCACCTACCCCATCGCCCCCAGCCTGGCAGGCTCGGGGCCTGGGCACCGCCCGGTTGCAGCTGGTAGAGTTCTCAGCCT
TCGTGGAACCGCCAGATGCAGTTGATTCTTACCAGAGGCACCTGTTCGTGCACATCAGCCAGCACTGCCCCAGCCCCGGAGCGCCGCCGC
TCGAGAGTGTGGACGTCCGGCAGATCTACGACAAATTCCCTGAGAAAAAGGGTGGCCTCCGAGAGCTATATGATCGTGGCCCCCCCCATG
CCTTCTTCCTGGTCAAGTTCTGGGCGGACCTGAACTGGGGCCCAAGTGGTGAGGAGGCAGGGGCCGGTGGCAGCATCAGCAGTGGTGGCT
TCTACGGAGTGAGCAGCCAGTATGAGAGCCTGGAACACATGACCCTCACCTGTTCCTCCAAGGTCTGCTCTTTTGGCAAGCAGGTGGTGG
AGAAGGTGGAGACGGAACGGGCCCAGCTGGAGGACGGCAGATTTGTGTACCGCCTGCTGCGCTCGCCCATGTGCGAGTACCTGGTGAATT
TCTTGCACAAGTTGCGGCAGCTGCCTGAGCGATACATGATGAACAGCGTCCTGGAAAACTTCACCATCCTCCAGGTGGTGACAAACAGAG
ACACCCAGGAACTGCTGCTCTGCACCGCCTATGTCTTCGAGGTCTCCACCAGCGAGCGTGGGGCCCAGCATCACATTTACCGCCTGGTCA
GGGACTGAAGGGGGACCCCAAAACTGGCTCACCCCCCAGAACACCCTCCTCCCAGGGAGGGTCCTCCAGCTCACCTCATGCTTCTTATTT
GGGGAGAGGGCTGTGATGTAAAGGGGTTGACCTCAGAGGCCTAAGCAACTGGGGCCATCCCCCCCATTAGAGGGGCCCCCAAAACTTGGT
TGGAGAGCTGAACAGGCTGGGACTGAGGAAAGGATAAACCCCGATATTGGGACCTCACAGTGGGTGTCTGAAAGGACAGATCACTCCGGA
GTATCAGGGATTGTGGGGACAGGAGTGAGACAACCCCCCAGGTACAGCACTGGCTTTTCTTTTCAGCCCCTGACAGGCCACCCCCACTCC
TCTGCATGTCTTGGAGAGCGCTAGTTACACATTGGCTTGTCCCCTTTACTTTTTCCCAGCCACCCCTCCCCCTGAAATTTCTGCCCCTCT
CTACCACCCTCACTCCATGACCTGTGAGATCACAAAGTGAAGATGAACCCTTTCTGTGCAGGAGCAGAGCCAGGTGGGCCCTGGACATTT
TTTTTTTTTTTAATATAACGAGATATTTATAAGTGGGTGCTAGGGTCTTGACTTTATCTCCGCTGCACAAGCAGTGTGTTGAACTTTCTA
ATCTCATCCCTCTCCTAAGTGAGCCCTGAGCTAGACGGTTTCCTTCCTCCCCTCTCAAAGTTTGTTTGTTTGTGTTCTGACAGAGGATAA

>89927_89927_11_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000444215_TEAD2_chr19_49854622_ENST00000598810_length(amino acids)=747AA_BP=476
MLSVRGHPVGAGGPRPGRQGSRSEGLVTARTERIASSRPRGPRGLLGTRSVGHLPRGAQALKVEGRNALAAGAWPGRTQPASPATVGDFQ
GEGAHLPSGARRMLQLLVLKIEDPGCFWVIIKGCSPFLDHDVDYQKLNSAMNDFYNSTCQDIEIKPLTLEEGQVCVVYCEELKCWCRAIV
KSITSSADQYLAECFLVDFAKNIPVKSKNIRVVVESFMQLPYRAKKFSLYCTKPVTLHIDFCRDSTDIVPAKKWDNAAIQYFQNLLKATT
QVEARLCAVEEDTFEVYLYVTIKDEKVCVNDDLVAKNYACYMSPTKNKNLDYLEKPRLNIKSAPSFNKLNPALTLWPMFLQGKDVQGMED
SHGVNFPAQSLQHTWCKGIVGDLRPTATAQDKAVKCNMDSLRDSPKDKSEKKHHCISLKDTNKRVESSVYWPAKRGITIYADPDVPEASA
LSQKSNEKPLRLTEKKEYDEKNSCVNVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPP
DAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVS
SQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQEL

--------------------------------------------------------------
>89927_89927_12_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000444215_TEAD2_chr19_49854622_ENST00000601519_length(transcript)=2987nt_BP=1441nt
CGACGCCTCAAGGCCTGCTCAGCGTGCGCGGGCATCCGGTGGGTGCGGGAGGCCCGAGGCCAGGCAGGCAGGGATCCCGCAGCGAGGGGC
TGGTTACTGCCAGGACGGAGCGCATTGCCTCGAGCCGACCCCGGGGTCCGCGAGGGCTCCTGGGGACGAGGAGTGTGGGGCACCTGCCGC
GGGGGGCCCAGGCGCTAAAGGTGGAGGGAAGGAACGCACTCGCGGCGGGGGCCTGGCCGGGGCGGACGCAGCCAGCCTCACCCGCGACGG
TAGGGGACTTCCAGGGCGAGGGGGCCCATCTGCCCTCGGGCGCCAGGAGGATGCTCCAGCTCCTGGTGCTGAAGATTGAAGATCCAGGTT
GCTTCTGGGTTATTATAAAAGGGTGTAGTCCCTTTTTAGATCATGATGTCGATTATCAAAAATTAAATAGTGCCATGAATGACTTCTACA
ACAGCACGTGTCAAGATATAGAAATAAAACCCTTAACATTGGAAGAAGGACAGGTGTGTGTGGTCTATTGTGAGGAGCTAAAGTGCTGGT
GCAGGGCCATTGTCAAATCAATTACGTCTTCCGCAGACCAGTACCTGGCAGAATGTTTCCTTGTGGACTTTGCCAAGAACATTCCAGTCA
AATCTAAAAACATCCGAGTTGTAGTAGAATCGTTTATGCAGCTTCCCTATAGAGCAAAAAAATTCAGCCTGTACTGCACAAAGCCTGTCA
CATTACACATTGACTTCTGCCGAGACAGTACTGACATTGTACCTGCCAAGAAGTGGGACAATGCAGCTATTCAGTACTTTCAGAACCTTC
TGAAAGCAACTACCCAGGTGGAAGCCAGATTATGTGCTGTGGAAGAAGATACATTTGAGGTTTACCTTTATGTAACTATAAAAGATGAAA
AAGTTTGTGTTAATGATGATCTTGTTGCAAAGAACTATGCTTGTTATATGTCACCTACAAAGAATAAAAACCTTGATTATTTAGAAAAAC
CAAGATTGAATATAAAATCAGCACCCTCCTTCAATAAACTCAATCCAGCACTTACACTCTGGCCAATGTTTTTGCAAGGAAAAGATGTTC
AAGGAATGGAAGATTCACATGGTGTAAATTTTCCGGCACAATCTCTGCAACATACATGGTGCAAGGGTATTGTCGGTGACCTCAGGCCAA
CAGCCACAGCACAGGACAAAGCTGTAAAATGTAATATGGATTCATTGAGAGATTCACCTAAAGACAAATCTGAAAAGAAACACCATTGCA
TCTCTTTAAAAGATACAAATAAGCGTGTTGAATCCTCAGTGTACTGGCCAGCAAAAAGAGGCATAACCATATATGCTGATCCAGATGTAC
CAGAAGCAAGTGCTTTAAGTCAGAAGTCAAATGAGAAACCTCTTAGATTGACTGAGAAGAAAGAATATGATGAGAAGAATAGCTGTGTGA
ATGTGAAGCCATTCTCACAGACACCGTTCACCTTGTCACTGACTCCCCCATCTACTGACCTCCCAGGGTACGAGCCCCCCCAAGCCCTCT
CACCCCTGCCCCCACCTACCCCATCGCCCCCAGCCTGGCAGGCTCGGGGCCTGGGCACCGCCCGGTTGCAGCTGGTAGAGTTCTCAGCCT
TCGTGGAACCGCCAGATGCAGTTGATTCTTACCAGAGGCACCTGTTCGTGCACATCAGCCAGCACTGCCCCAGCCCCGGAGCGCCGCCGC
TCGAGAGTGTGGACGTCCGGCAGATCTACGACAAATTCCCTGAGAAAAAGGGTGGCCTCCGAGAGCTATATGATCGTGGCCCCCCCCATG
CCTTCTTCCTGGTCAAGTTCTGGGCGGACCTGAACTGGGGCCCAAGTGGTGAGGAGGCAGGGGCCGGTGGCAGCATCAGCAGTGGTGGCT
TCTACGGAGTGAGCAGCCAGTATGAGAGCCTGGAACACATGACCCTCACCTGTTCCTCCAAGGTCTGCTCTTTTGGCAAGCAGGTGGTGG
AGAAGGTGGAGACGGAACGGGCCCAGCTGGAGGACGGCAGATTTGTGTACCGCCTGCTGCGCTCGCCCATGTGCGAGTACCTGGTGAATT
TCTTGCACAAGTTGCGGCAGCTGCCTGAGCGATACATGATGAACAGCGTCCTGGAAAACTTCACCATCCTCCAGGTGGTGACAAACAGAG
ACACCCAGGAACTGCTGCTCTGCACCGCCTATGTCTTCGAGGTCTCCACCAGCGAGCGTGGGGCCCAGCATCACATTTACCGCCTGGTCA
GGGACTGAAGGGGGACCCCAAAACTGGCTCACCCCCCAGAACACCCTCCTCCCAGGGAGGGTCCTCCAGCTCACCTCATGCTTCTTATTT
GGGGAGAGGGCTGTGATGTAAAGGGGTTGACCTCAGAGGCCTAAGCAACTGGGGCCATCCCCCCCATTAGAGGGGCCCCCAAAACTTGGT
TGGAGAGCTGAACAGGCTGGGACTGAGGAAAGGATAAACCCCGATATTGGGACCTCACAGTGGGTGTCTGAAAGGACAGATCACTCCGGA
GTATCAGGGATTGTGGGGACAGGAGTGAGACAACCCCCCAGGTACAGCACTGGCTTTTCTTTTCAGCCCCTGACAGGCCACCCCCACTCC
TCTGCATGTCTTGGAGAGCGCTAGTTACACATTGGCTTGTCCCCTTTACTTTTTCCCAGCCACCCCTCCCCCTGAAATTTCTGCCCCTCT
CTACCACCCTCACTCCATGACCTGTGAGATCACAAAGTGAAGATGAACCCTTTCTGTGCAGGAGCAGAGCCAGGTGGGCCCTGGACATTT
TTTTTTTTTTTAATATAACGAGATATTTATAAGTGGGTGCTAGGGTCTTGACTTTATCTCCGCTGCACAAGCAGTGTGTTGAACTTTCTA
ATCTCATCCCTCTCCTAAGTGAGCCCTGAGCTAGACGGTTTCCTTCCTCCCCTCTCAAAGTTTGTTTGTTTGTGTTCTGACAGAGGATAA

>89927_89927_12_TDRD12-TEAD2_TDRD12_chr19_33268135_ENST00000444215_TEAD2_chr19_49854622_ENST00000601519_length(amino acids)=747AA_BP=476
MLSVRGHPVGAGGPRPGRQGSRSEGLVTARTERIASSRPRGPRGLLGTRSVGHLPRGAQALKVEGRNALAAGAWPGRTQPASPATVGDFQ
GEGAHLPSGARRMLQLLVLKIEDPGCFWVIIKGCSPFLDHDVDYQKLNSAMNDFYNSTCQDIEIKPLTLEEGQVCVVYCEELKCWCRAIV
KSITSSADQYLAECFLVDFAKNIPVKSKNIRVVVESFMQLPYRAKKFSLYCTKPVTLHIDFCRDSTDIVPAKKWDNAAIQYFQNLLKATT
QVEARLCAVEEDTFEVYLYVTIKDEKVCVNDDLVAKNYACYMSPTKNKNLDYLEKPRLNIKSAPSFNKLNPALTLWPMFLQGKDVQGMED
SHGVNFPAQSLQHTWCKGIVGDLRPTATAQDKAVKCNMDSLRDSPKDKSEKKHHCISLKDTNKRVESSVYWPAKRGITIYADPDVPEASA
LSQKSNEKPLRLTEKKEYDEKNSCVNVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPP
DAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVS
SQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQEL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TDRD12-TEAD2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TDRD12-TEAD2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TDRD12-TEAD2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource