FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:TET2-PPA2 (FusionGDB2 ID:90174)

Fusion Gene Summary for TET2-PPA2

check button Fusion gene summary
Fusion gene informationFusion gene name: TET2-PPA2
Fusion gene ID: 90174
HgeneTgene
Gene symbol

TET2

PPA2

Gene ID

54790

27068

Gene nametet methylcytosine dioxygenase 2inorganic pyrophosphatase 2
SynonymsKIAA1546|MDSHSPC124|SCFAI|SCFI|SID6-306
Cytomap

4q24

4q24

Type of geneprotein-codingprotein-coding
Descriptionmethylcytosine dioxygenase TET2probable methylcytosine dioxygenase TET2tet oncogene family member 2inorganic pyrophosphatase 2, mitochondrialPPase 2pyrophosphatase (inorganic) 2pyrophosphatase SID6-306pyrophosphate phospho-hydrolase 2
Modification date2020032220200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000504042, ENST00000305737, 
ENST00000380013, ENST00000394764, 
ENST00000413648, ENST00000513237, 
ENST00000540549, ENST00000545826, 
ENST00000341695, ENST00000348706, 
ENST00000354147, ENST00000357415, 
ENST00000380004, ENST00000432483, 
ENST00000310267, ENST00000509426, 
Fusion gene scores* DoF score11 X 6 X 11=72617 X 10 X 8=1360
# samples 1518
** MAII scorelog2(15/726*10)=-2.27500704749987
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(18/1360*10)=-2.91753783980803
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TET2 [Title/Abstract] AND PPA2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTET2(106068136)-PPA2(106370560), # samples:1
TET2(106111662)-PPA2(106320321), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTET2

GO:0006211

5-methylcytosine catabolic process

24315485

HgeneTET2

GO:0006493

protein O-linked glycosylation

23222540

HgeneTET2

GO:0080111

DNA demethylation

24315485


check buttonFusion gene breakpoints across TET2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across PPA2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-Cancer135NTET2chr4

106068136

+PPA2chr4

106370560

-
ChimerDB4Non-CancerTCGA-38-4626-11ATET2chr4

106111662

+PPA2chr4

106320321

-


Top

Fusion Gene ORF analysis for TET2-PPA2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000504042ENST00000341695TET2chr4

106068136

+PPA2chr4

106370560

-
3UTR-3CDSENST00000504042ENST00000341695TET2chr4

106111662

+PPA2chr4

106320321

-
3UTR-3CDSENST00000504042ENST00000348706TET2chr4

106068136

+PPA2chr4

106370560

-
3UTR-3CDSENST00000504042ENST00000348706TET2chr4

106111662

+PPA2chr4

106320321

-
3UTR-3CDSENST00000504042ENST00000354147TET2chr4

106111662

+PPA2chr4

106320321

-
3UTR-3CDSENST00000504042ENST00000357415TET2chr4

106111662

+PPA2chr4

106320321

-
3UTR-3CDSENST00000504042ENST00000380004TET2chr4

106111662

+PPA2chr4

106320321

-
3UTR-3CDSENST00000504042ENST00000432483TET2chr4

106111662

+PPA2chr4

106320321

-
3UTR-5UTRENST00000504042ENST00000310267TET2chr4

106068136

+PPA2chr4

106370560

-
3UTR-5UTRENST00000504042ENST00000509426TET2chr4

106068136

+PPA2chr4

106370560

-
3UTR-5UTRENST00000504042ENST00000509426TET2chr4

106111662

+PPA2chr4

106320321

-
3UTR-intronENST00000504042ENST00000310267TET2chr4

106111662

+PPA2chr4

106320321

-
3UTR-intronENST00000504042ENST00000354147TET2chr4

106068136

+PPA2chr4

106370560

-
3UTR-intronENST00000504042ENST00000357415TET2chr4

106068136

+PPA2chr4

106370560

-
3UTR-intronENST00000504042ENST00000380004TET2chr4

106068136

+PPA2chr4

106370560

-
3UTR-intronENST00000504042ENST00000432483TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-3CDSENST00000305737ENST00000341695TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000305737ENST00000348706TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000305737ENST00000354147TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000305737ENST00000357415TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000305737ENST00000380004TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000305737ENST00000432483TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000380013ENST00000341695TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-3CDSENST00000380013ENST00000341695TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000380013ENST00000348706TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-3CDSENST00000380013ENST00000348706TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000380013ENST00000354147TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000380013ENST00000357415TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000380013ENST00000380004TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000380013ENST00000432483TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000394764ENST00000341695TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-3CDSENST00000394764ENST00000341695TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000394764ENST00000348706TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-3CDSENST00000394764ENST00000348706TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000394764ENST00000354147TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000394764ENST00000357415TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000394764ENST00000380004TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000394764ENST00000432483TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-3CDSENST00000413648ENST00000341695TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-3CDSENST00000413648ENST00000348706TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-3CDSENST00000513237ENST00000341695TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-3CDSENST00000513237ENST00000348706TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-3CDSENST00000540549ENST00000341695TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-3CDSENST00000540549ENST00000348706TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-3CDSENST00000545826ENST00000341695TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-3CDSENST00000545826ENST00000348706TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-5UTRENST00000305737ENST00000509426TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-5UTRENST00000380013ENST00000310267TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-5UTRENST00000380013ENST00000509426TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-5UTRENST00000380013ENST00000509426TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-5UTRENST00000394764ENST00000310267TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-5UTRENST00000394764ENST00000509426TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-5UTRENST00000394764ENST00000509426TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-5UTRENST00000413648ENST00000310267TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-5UTRENST00000413648ENST00000509426TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-5UTRENST00000513237ENST00000310267TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-5UTRENST00000513237ENST00000509426TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-5UTRENST00000540549ENST00000310267TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-5UTRENST00000540549ENST00000509426TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-5UTRENST00000545826ENST00000310267TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-5UTRENST00000545826ENST00000509426TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000305737ENST00000310267TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-intronENST00000380013ENST00000310267TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-intronENST00000380013ENST00000354147TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000380013ENST00000357415TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000380013ENST00000380004TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000380013ENST00000432483TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000394764ENST00000310267TET2chr4

106111662

+PPA2chr4

106320321

-
5UTR-intronENST00000394764ENST00000354147TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000394764ENST00000357415TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000394764ENST00000380004TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000394764ENST00000432483TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000413648ENST00000354147TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000413648ENST00000357415TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000413648ENST00000380004TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000413648ENST00000432483TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000513237ENST00000354147TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000513237ENST00000357415TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000513237ENST00000380004TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000513237ENST00000432483TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000540549ENST00000354147TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000540549ENST00000357415TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000540549ENST00000380004TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000540549ENST00000432483TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000545826ENST00000354147TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000545826ENST00000357415TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000545826ENST00000380004TET2chr4

106068136

+PPA2chr4

106370560

-
5UTR-intronENST00000545826ENST00000432483TET2chr4

106068136

+PPA2chr4

106370560

-
intron-3CDSENST00000305737ENST00000341695TET2chr4

106068136

+PPA2chr4

106370560

-
intron-3CDSENST00000305737ENST00000348706TET2chr4

106068136

+PPA2chr4

106370560

-
intron-3CDSENST00000413648ENST00000341695TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000413648ENST00000348706TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000413648ENST00000354147TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000413648ENST00000357415TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000413648ENST00000380004TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000413648ENST00000432483TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000513237ENST00000341695TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000513237ENST00000348706TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000513237ENST00000354147TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000513237ENST00000357415TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000513237ENST00000380004TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000513237ENST00000432483TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000540549ENST00000341695TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000540549ENST00000348706TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000540549ENST00000354147TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000540549ENST00000357415TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000540549ENST00000380004TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000540549ENST00000432483TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000545826ENST00000341695TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000545826ENST00000348706TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000545826ENST00000354147TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000545826ENST00000357415TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000545826ENST00000380004TET2chr4

106111662

+PPA2chr4

106320321

-
intron-3CDSENST00000545826ENST00000432483TET2chr4

106111662

+PPA2chr4

106320321

-
intron-5UTRENST00000305737ENST00000310267TET2chr4

106068136

+PPA2chr4

106370560

-
intron-5UTRENST00000305737ENST00000509426TET2chr4

106068136

+PPA2chr4

106370560

-
intron-5UTRENST00000413648ENST00000509426TET2chr4

106111662

+PPA2chr4

106320321

-
intron-5UTRENST00000513237ENST00000509426TET2chr4

106111662

+PPA2chr4

106320321

-
intron-5UTRENST00000540549ENST00000509426TET2chr4

106111662

+PPA2chr4

106320321

-
intron-5UTRENST00000545826ENST00000509426TET2chr4

106111662

+PPA2chr4

106320321

-
intron-intronENST00000305737ENST00000354147TET2chr4

106068136

+PPA2chr4

106370560

-
intron-intronENST00000305737ENST00000357415TET2chr4

106068136

+PPA2chr4

106370560

-
intron-intronENST00000305737ENST00000380004TET2chr4

106068136

+PPA2chr4

106370560

-
intron-intronENST00000305737ENST00000432483TET2chr4

106068136

+PPA2chr4

106370560

-
intron-intronENST00000413648ENST00000310267TET2chr4

106111662

+PPA2chr4

106320321

-
intron-intronENST00000513237ENST00000310267TET2chr4

106111662

+PPA2chr4

106320321

-
intron-intronENST00000540549ENST00000310267TET2chr4

106111662

+PPA2chr4

106320321

-
intron-intronENST00000545826ENST00000310267TET2chr4

106111662

+PPA2chr4

106320321

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

Top

Fusion Genomic Features for TET2-PPA2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for TET2-PPA2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:106068136/:106370560)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

Fusion Gene Sequence for TET2-PPA2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

Top

Fusion Gene PPI Analysis for TET2-PPA2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for TET2-PPA2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for TET2-PPA2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource