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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
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Fusion gene:TFDP2-COG5 (FusionGDB2 ID:90298)

Fusion Gene Summary for TFDP2-COG5

Fusion gene summary

Fusion gene information	Fusion gene name: TFDP2-COG5
	Fusion gene ID: 90298
		Hgene	Tgene
	Gene symbol	TFDP2	COG5
	Gene ID	7029	10466
	Gene name	transcription factor Dp-2	component of oligomeric golgi complex 5
	Synonyms	DP2	CDG2I\|GOLTC1\|GTC90
	Cytomap	3q23	7q22.3
	Type of gene	protein-coding	protein-coding
	Description	transcription factor Dp-2transcription factor Dp-2 (E2F dimerization partner 2)	conserved oligomeric Golgi complex subunit 513S golgi transport complex 1 90 kDa subunitCOG complex subunit 5conserved oligomeric Golgi complex protein 5
	Modification date	20200313	20200313
	UniProtAcc	.	Q9UP83
	Ensembl transtripts involved in fusion gene	ENST00000489671, ENST00000317104, ENST00000467072, ENST00000310282, ENST00000397991, ENST00000464782, ENST00000477292, ENST00000479040, ENST00000486111, ENST00000495310, ENST00000499676,	ENST00000475638, ENST00000297135, ENST00000347053, ENST00000393603,
Fusion gene scores	* DoF score	13 X 10 X 10=1300	14 X 10 X 8=1120
	# samples	18	13
	** MAII score	log2(18/1300*10)=-2.85244281158614 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(13/1120*10)=-3.10691520391651 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: TFDP2 [Title/Abstract] AND COG5 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	TFDP2(141811903)-COG5(106964966), # samples:3
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	TFDP2	GO:0045892	negative regulation of transcription, DNA-templated	20176812
Hgene	TFDP2	GO:0045944	positive regulation of transcription by RNA polymerase II	7739537
Tgene	COG5	GO:0048219	inter-Golgi cisterna vesicle-mediated transport	9792665

Fusion gene breakpoints across TFDP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across COG5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	HNSC	TCGA-CR-5247-01A	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
ChimerDB4	HNSC	TCGA-CR-5247	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-

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Fusion Gene ORF analysis for TFDP2-COG5

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000489671	ENST00000475638	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
5UTR-3CDS	ENST00000317104	ENST00000297135	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
5UTR-3CDS	ENST00000317104	ENST00000347053	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
5UTR-3CDS	ENST00000317104	ENST00000393603	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
5UTR-3CDS	ENST00000467072	ENST00000297135	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
5UTR-3CDS	ENST00000467072	ENST00000347053	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
5UTR-3CDS	ENST00000467072	ENST00000393603	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
5UTR-intron	ENST00000317104	ENST00000475638	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
5UTR-intron	ENST00000467072	ENST00000475638	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
In-frame	ENST00000489671	ENST00000297135	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
In-frame	ENST00000489671	ENST00000347053	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
In-frame	ENST00000489671	ENST00000393603	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000310282	ENST00000297135	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000310282	ENST00000347053	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000310282	ENST00000393603	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000397991	ENST00000297135	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000397991	ENST00000347053	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000397991	ENST00000393603	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000464782	ENST00000297135	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000464782	ENST00000347053	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000464782	ENST00000393603	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000477292	ENST00000297135	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000477292	ENST00000347053	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000477292	ENST00000393603	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000479040	ENST00000297135	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000479040	ENST00000347053	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000479040	ENST00000393603	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000486111	ENST00000297135	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000486111	ENST00000347053	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000486111	ENST00000393603	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000495310	ENST00000297135	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000495310	ENST00000347053	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000495310	ENST00000393603	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000499676	ENST00000297135	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000499676	ENST00000347053	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-3CDS	ENST00000499676	ENST00000393603	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-intron	ENST00000310282	ENST00000475638	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-intron	ENST00000397991	ENST00000475638	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-intron	ENST00000464782	ENST00000475638	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-intron	ENST00000477292	ENST00000475638	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-intron	ENST00000479040	ENST00000475638	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-intron	ENST00000486111	ENST00000475638	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-intron	ENST00000495310	ENST00000475638	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-
intron-intron	ENST00000499676	ENST00000475638	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000489671	TFDP2	chr3	141811903	-	ENST00000347053	COG5	chr7	106964966	-	3875	513	582	1913	443
ENST00000489671	TFDP2	chr3	141811903	-	ENST00000297135	COG5	chr7	106964966	-	2929	513	582	1976	464
ENST00000489671	TFDP2	chr3	141811903	-	ENST00000393603	COG5	chr7	106964966	-	4540	513	582	1865	427

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000489671	ENST00000347053	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-	0.000576005	0.999424
ENST00000489671	ENST00000297135	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-	0.000418477	0.9995815
ENST00000489671	ENST00000393603	TFDP2	chr3	141811903	-	COG5	chr7	106964966	-	0.000573847	0.9994261

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Fusion Genomic Features for TFDP2-COG5

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TFDP2-COG5

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:141811903/chr7:106964966)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	COG5 Q9UP83
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Required for normal Golgi function. {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000310282

432_446

387.0

Compositional bias

Note=Asp/Glu-rich (acidic%3B NCB domain)

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000397991

432_446

419.0

Compositional bias

Note=Asp/Glu-rich (acidic%3B NCB domain)

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000467072

432_446

387.0

Compositional bias

Note=Asp/Glu-rich (acidic%3B NCB domain)

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000477292

432_446

311.0

Compositional bias

Note=Asp/Glu-rich (acidic%3B NCB domain)

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000479040

432_446

386.0

Compositional bias

Note=Asp/Glu-rich (acidic%3B NCB domain)

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000486111

432_446

387.0

Compositional bias

Note=Asp/Glu-rich (acidic%3B NCB domain)

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000489671

432_446

447.0

Compositional bias

Note=Asp/Glu-rich (acidic%3B NCB domain)

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000495310

432_446

350.0

Compositional bias

Note=Asp/Glu-rich (acidic%3B NCB domain)

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000499676

432_446

387.0

Compositional bias

Note=Asp/Glu-rich (acidic%3B NCB domain)

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000310282

129_210

387.0

DNA binding

Ontology_term=ECO:0000255

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000397991

129_210

419.0

DNA binding

Ontology_term=ECO:0000255

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000467072

129_210

387.0

DNA binding

Ontology_term=ECO:0000255

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000477292

129_210

311.0

DNA binding

Ontology_term=ECO:0000255

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000479040

129_210

386.0

DNA binding

Ontology_term=ECO:0000255

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000486111

129_210

387.0

DNA binding

Ontology_term=ECO:0000255

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000489671

129_210

447.0

DNA binding

Ontology_term=ECO:0000255

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000495310

129_210

350.0

DNA binding

Ontology_term=ECO:0000255

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000499676

129_210

387.0

DNA binding

Ontology_term=ECO:0000255

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000310282

176_210

387.0

Motif

Note=DEF box

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000397991

176_210

419.0

Motif

Note=DEF box

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000467072

176_210

387.0

Motif

Note=DEF box

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000477292

176_210

311.0

Motif

Note=DEF box

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000479040

176_210

386.0

Motif

Note=DEF box

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000486111

176_210

387.0

Motif

Note=DEF box

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000489671

176_210

447.0

Motif

Note=DEF box

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000495310

176_210

350.0

Motif

Note=DEF box

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000499676

176_210

387.0

Motif

Note=DEF box

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000310282

219_292

387.0

Region

Dimerization

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000310282

229_261

387.0

Region

Note=DCB1

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000310282

274_330

387.0

Region

Note=DCB2

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000397991

219_292

419.0

Region

Dimerization

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000397991

229_261

419.0

Region

Note=DCB1

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000397991

274_330

419.0

Region

Note=DCB2

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000467072

219_292

387.0

Region

Dimerization

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000467072

229_261

387.0

Region

Note=DCB1

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000467072

274_330

387.0

Region

Note=DCB2

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000477292

219_292

311.0

Region

Dimerization

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000477292

229_261

311.0

Region

Note=DCB1

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000477292

274_330

311.0

Region

Note=DCB2

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000479040

219_292

386.0

Region

Dimerization

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000479040

229_261

386.0

Region

Note=DCB1

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000479040

274_330

386.0

Region

Note=DCB2

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000486111

219_292

387.0

Region

Dimerization

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000486111

229_261

387.0

Region

Note=DCB1

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000486111

274_330

387.0

Region

Note=DCB2

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000489671

219_292

447.0

Region

Dimerization

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000489671

229_261

447.0

Region

Note=DCB1

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000489671

274_330

447.0

Region

Note=DCB2

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000495310

219_292

350.0

Region

Dimerization

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000495310

229_261

350.0

Region

Note=DCB1

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000495310

274_330

350.0

Region

Note=DCB2

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000499676

219_292

387.0

Region

Dimerization

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000499676

229_261

387.0

Region

Note=DCB1

Hgene

TFDP2

chr3:141811903

chr7:106964966

ENST00000499676

274_330

387.0

Region

Note=DCB2

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Fusion Gene Sequence for TFDP2-COG5

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>90298_90298_1_TFDP2-COG5_TFDP2_chr3_141811903_ENST00000489671_COG5_chr7_106964966_ENST00000297135_length(transcript)=2929nt_BP=513nt
AAAGCTCGCGCGGGGGAAGCGGGGCTGTAGCTGGGCAGGGAGAGGGCGGACGAAATCGGTAGCGATCTCGGCTGCGGCGCTGCCGCAGCT
GCCCGGCCCGCGGGGCGCGCCCTGACCCTTCATCTTTGGGCAGGCTCGAGGGCGCGCGCACGGTTGGCGTTCTGGGGCCTCAAACTCCTG
GGCCTTGACCGGGCAGGCCGCGTCTCCCCGGGTGTGAGTCCACCGGGACCCGGCCGCCGCCTAAGCGCGGGCGCCACAGAAGCGGCGGCG
CCCGAAGACGCGCTCCTGGCTCGGCCCGACAGCCTCGCTTGGCCGCCAGTTCTTCTGCAGCCGAAGGCGGTTGTTCTTTTAAAGAATTAT
TGAAGACGAAGGTTTTTTTCTTTTTATTTTTTTAATGGCTTTACAGAATCTTAAATAGAATACAGTTTGACATGACGGCAAAAAATGTTG
GTTTGACTTCCACAAATGCAGAAGTAAGAGGATTTATAGATCAGAATCTCAGTCCAACAAAAGGATGGACAACCGGAAATTTTCTACACA
TTTTGGAATTCAGTTACTCAGGCACTTTCTTCTCAATTTCATATGGCAACAAACTCTTCGATGTTTTTGAAGCAGGCATTTGAAGGAGAA
TACCCTAAATTATTACGTCTTTATAATGACTTATGGAAGCGTCTTCAACAATACAGTCAGCATATCCAAGGGAATTTTAATGCAAGTGGA
ACTACAGACCTCTATGTTGACCTACAACACATGGAAGATGATGCACAAGATATATTCATACCAAAAAAGCCAGATTATGATCCAGAAAAG
GCTTTGAAAGACTCACTACAACCCTATGAGGCTGCTTATCTATCAAAATCCTTATCTCGACTCTTCGATCCTATCAACTTGGTTTTTCCC
CCGGGTGGTCGTAATCCTCCTTCCTCTGATGAACTTGATGGTATTATTAAAACTATAGCAAGTGAACTAAATGTTGCTGCTGTTGATACA
AACCTCACATTAGCTGTGTCAAAAAATGTGGCAAAGACCATCCAGTTATACAGTGTAAAATCAGAGCAGCTTCTCTCCACACAAGGAGAT
GCAAGTCAGGTGATTGGGCCTCTTACTGAAGGACAGAGAAGAAATGTGGCAGTAGTGAATTCATTGTATAAGTTGCACCAATCAGTAACA
AAGGTTGTTTCCAGTCAGAGCTCATTCCCACTGGCAGCTGAGCAAACTATAATTTCAGCTCTAAAGGCTATTCATGCTCTTATGGAAAAT
GCTGTGCAACCCTTACTCACTTCTGTGGGAGATGCTATAGAGGCCATAATCATCACCATGCATCAAGAAGACTTTTCTGGGTCATTATCC
AGCTCAGGAAAACCTGATGTTCCTTGTTCTCTGTACATGAAGGAGCTACAAGGTTTCATTGCCAGAGTTATGAGTGACTATTTTAAACAC
TTTGAATGCTTGGATTTTGTCTTTGACAACACTGAGGCTATTGCCCAAAGAGCTGTTGAACTTTTTATCCGCCATGCCAGTCTCATAAGA
CCTCTTGGTGAAGGTGGGAAAATGCGACTTGCTGCTGATTTTGCACAGATGGAGTTGGCTGTGGGTCCATTCTGTAGACGAGTATCTGAT
TTAGGAAAGTCCTATCGGATGCTGAGATCATTCAGACCTCTGCTCTTCCAGGCAAGTGAACATGTAGCCAGTAGTCCTGCATTGGGGGAT
GTGATTCCGTTCAGCATCATTATTCAGTTTTTGTTCACGAGAGCACCCGCTGAACTGAAATCTCCTTTCCAGAGGGCAGAGTGGTCCCAC
ACACGCTTCTCTCAGTGGCTGGATGACCATCCATCTGAAAAGGACAGGCTCCTCCTCATCAGGGGAGCCCTGGAAGCTTATGTTCAATCA
GTGAGAAGTAGAGAAGGCAAAGAATTTGCACCAGTTTATCCCATAATGGTTCAGCTGCTTCAAAAGGCTATGTCTGCTCTTCAGTAATGA
CATGAAATCTTTGTTCATCTCCACTTTGTGCTAACCCATTCATAGTTGGCAGTTAAACACATACTCCAAAAGACTGCTACTATCTACTAT
TTTAAGAATGTAATTGATTGTTCGGTATTTCCTATCGACGTTTATTTACCTCTTTAGCACTTATACTTTAGCATAAAAAATGTTGAGTTA
TCACCACCTTTCAATTCCATGGACCTGATTTTTCCAGAAAGATGTTTTCCTCTTTCAGATTTTTGTACAAGGCTAAAATGTCTTTCCCAT
CCATAACCAAGTCCTCCTATGGGTACATAAACCCAAAGTCCCCACTTCTTTTAAAGGGATATGATCAAGTTATAACATGTACCCTGCTTC
CCCCAACCCTGCCTTCTTCACTAAATAAGCATGTAGCTCAGTGGTTTCCAAATTTGGCTGCACATTCATACCAATCACCAGGGGATTTTT
TTAAAATCCTGATGCCCAACTTGCACTCCACATTAATTAACATGTCTAGGAGTGGGAGCCTGACAGACACCACTATTAAAAAAAAAAAAA
ATCCCCAAAATGATTCCAATAGACAACAAAGTTGAGGAACCACTGGCACATCCCAAGCTAAGATACAAGGTTAAATGGCCTTTTTAAGTA
TGTCATACTGGATCTTTAAATAAAGCAAGGCTTTTGTTACACTTTGTCATGTTATTAAAAGCAGACCTTTGGGCTGTTTAACCGTGTAAC
AAAAATGCCACGTGAAAAATAAAAATTTTTATTGTATAGCAATTCTCTATAAATAGTAGATAATCTAAGTCCTTATTTTCTGATGGCTCT
TGTTCCACTATTAACATTGTTTTTAATTTTTAAAATCCTATCAGCAGCCTCCTAATTAGCAGTGTTAGGAATTTGCCTTATGTTTTCCAT

>90298_90298_1_TFDP2-COG5_TFDP2_chr3_141811903_ENST00000489671_COG5_chr7_106964966_ENST00000297135_length(amino acids)=464AA_BP=
MATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQHIQGNFNASGTTDLYVDLQHMEDDAQDIFIPKKPDYDPEKALKDSLQPYEAAYL
SKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNVAAVDTNLTLAVSKNVAKTIQLYSVKSEQLLSTQGDASQVIGPLTEGQRR
NVAVVNSLYKLHQSVTKVVSSQSSFPLAAEQTIISALKAIHALMENAVQPLLTSVGDAIEAIIITMHQEDFSGSLSSSGKPDVPCSLYMK
ELQGFIARVMSDYFKHFECLDFVFDNTEAIAQRAVELFIRHASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPL
LFQASEHVASSPALGDVIPFSIIIQFLFTRAPAELKSPFQRAEWSHTRFSQWLDDHPSEKDRLLLIRGALEAYVQSVRSREGKEFAPVYP

--------------------------------------------------------------
>90298_90298_2_TFDP2-COG5_TFDP2_chr3_141811903_ENST00000489671_COG5_chr7_106964966_ENST00000347053_length(transcript)=3875nt_BP=513nt
AAAGCTCGCGCGGGGGAAGCGGGGCTGTAGCTGGGCAGGGAGAGGGCGGACGAAATCGGTAGCGATCTCGGCTGCGGCGCTGCCGCAGCT
GCCCGGCCCGCGGGGCGCGCCCTGACCCTTCATCTTTGGGCAGGCTCGAGGGCGCGCGCACGGTTGGCGTTCTGGGGCCTCAAACTCCTG
GGCCTTGACCGGGCAGGCCGCGTCTCCCCGGGTGTGAGTCCACCGGGACCCGGCCGCCGCCTAAGCGCGGGCGCCACAGAAGCGGCGGCG
CCCGAAGACGCGCTCCTGGCTCGGCCCGACAGCCTCGCTTGGCCGCCAGTTCTTCTGCAGCCGAAGGCGGTTGTTCTTTTAAAGAATTAT
TGAAGACGAAGGTTTTTTTCTTTTTATTTTTTTAATGGCTTTACAGAATCTTAAATAGAATACAGTTTGACATGACGGCAAAAAATGTTG
GTTTGACTTCCACAAATGCAGAAGTAAGAGGATTTATAGATCAGAATCTCAGTCCAACAAAAGGATGGACAACCGGAAATTTTCTACACA
TTTTGGAATTCAGTTACTCAGGCACTTTCTTCTCAATTTCATATGGCAACAAACTCTTCGATGTTTTTGAAGCAGGCATTTGAAGGAGAA
TACCCTAAATTATTACGTCTTTATAATGACTTATGGAAGCGTCTTCAACAATACAGTCAGCATATCCAAGGGAATTTTAATGCAAGTGGA
ACTACAGACCTCTATGTTGACCTACAACACATGGAAGATGATGCACAAGATATATTCATACCAAAAAAGCCAGATTATGATCCAGAAAAG
GCTTTGAAAGACTCACTACAACCCTATGAGGCTGCTTATCTATCAAAATCCTTATCTCGACTCTTCGATCCTATCAACTTGGTTTTTCCC
CCGGGTGGTCGTAATCCTCCTTCCTCTGATGAACTTGATGGTATTATTAAAACTATAGCAAGTGAACTAAATGTTGCTGCTGTTGATACA
AACCTCACATTAGCTGTGTCAAAAAATGTGGCAAAGACCATCCAGTTATACAGTGTAAAATCAGAGCAGCTTCTCTCCACACAAGGAGAT
GCAAGTCAGGTGATTGGGCCTCTTACTGAAGGACAGAGAAGAAATGTGGCAGTAGTGAATTCATTGTATAAGTTGCACCAATCAGTAACA
AAGGCTATTCATGCTCTTATGGAAAATGCTGTGCAACCCTTACTCACTTCTGTGGGAGATGCTATAGAGGCCATAATCATCACCATGCAT
CAAGAAGACTTTTCTGGGTCATTATCCAGCTCAGGAAAACCTGATGTTCCTTGTTCTCTGTACATGAAGGAGCTACAAGGTTTCATTGCC
AGAGTTATGAGTGACTATTTTAAACACTTTGAATGCTTGGATTTTGTCTTTGACAACACTGAGGCTATTGCCCAAAGAGCTGTTGAACTT
TTTATCCGCCATGCCAGTCTCATAAGACCTCTTGGTGAAGGTGGGAAAATGCGACTTGCTGCTGATTTTGCACAGATGGAGTTGGCTGTG
GGTCCATTCTGTAGACGAGTATCTGATTTAGGAAAGTCCTATCGGATGCTGAGATCATTCAGACCTCTGCTCTTCCAGGCAAGTGAACAT
GTAGCCAGTAGTCCTGCATTGGGGGATGTGATTCCGTTCAGCATCATTATTCAGTTTTTGTTCACGAGAGCACCCGCTGAACTGAAATCT
CCTTTCCAGAGGGCAGAGTGGTCCCACACACGCTTCTCTCAGTGGCTGGATGACCATCCATCTGAAAAGGACAGGCTCCTCCTCATCAGG
GGAGCCCTGGAAGCTTATGTTCAATCAGTGAGAAGTAGAGAAGGCAAAGAATTTGCACCAGTTTATCCCATAATGGTTCAGCTGCTTCAA
AAGGCTATGTCTGCTCTTCAGTAATGACATGAAATCTTTGTTCATCTCCACTTTGTGCTAACCCATTCATAGTTGGCAGTTAAACACATA
CTCCAAAAGACTGCTACTATCTACTATTTTAAGAATGTAATTGATTGTTCGGTATTTCCTATCGACGTTTATTTACCTCTTTAGCACTTA
TACTTTAGCATAAAAAATGTTGAGTTATCACCACCTTTCAATTCCATGGACCTGATTTTTCCAGAAAGATGTTTTCCTCTTTCAGATTTT
TGTACAAGGCTAAAATGTCTTTCCCATCCATAACCAAGTCCTCCTATGGGTACATAAACCCAAAGTCCCCACTTCTTTTAAAGGGATATG
ATCAAGTTATAACATGTACCCTGCTTCCCCCAACCCTGCCTTCTTCACTAAATAAGCATGTAGCTCAGTGGTTTCCAAATTTGGCTGCAC
ATTCATACCAATCACCAGGGGATTTTTTTAAAATCCTGATGCCCAACTTGCACTCCACATTAATTAACATGTCTAGGAGTGGGAGCCTGA
CAGACACCACTATTAAAAAAAAAAAAAATCCCCAAAATGATTCCAATAGACAACAAAGTTGAGGAACCACTGGCACATCCCAAGCTAAGA
TACAAGGTTAAATGGCCTTTTTAAGTATGTCATACTGGATCTTTAAATAAAGCAAGGCTTTTGTTACACTTTGTCATGTTATTAAAAGCA
GACCTTTGGGCTGTTTAACCGTGTAACAAAAATGCCACGTGAAAAATAAAAATTTTTATTGTATAGCAATTCTCTATAAATAGTAGATAA
TCTAAGTCCTTATTTTCTGATGGCTCTTGTTCCACTATTAACATTGTTTTTAATTTTTAAAATCCTATCAGCAGCCTCCTAATTAGCAGT
GTTAGGAATTTGCCTTATGTTTTCCATCTCATCTCCTGAACCTGTTATTCTGAGAACTCATAAATAAAATTCAGCCAAGATTAATCAATC
AATCAATCAATCAGTAGACGTCAGAGATAAGCAACTTTTTTTTCCATTTATTTGAAATAATATACAAGAATATAGTGTGCAAAATTTAGG
GGCAACATCATGAAGAAGTGTGATGAACTGAAATCAATTTTACAGCTGTGATTCCTAACCAGAAACACCACTTGGTAAGTAACATGAAAA
GCCATGATTGTAGCTCAGAGCAAAAGCAGCTGTATTGCCAATGTATTTGCTCTAATTTTAGACAGTTGGAGGAAAATTAAAGTGCAAGTG
TTGCACTGCAGTAAGTGCAAAGTCTGCCCCCACCATAAAGATTATGATGACAAAATATATTTAAGATACATGGCTGAGGAGATACAGAAC
ACGAAGTTAAAAAATACAATGGTGTTGACTGTTTGTTAATAGCACCATTACAGTGACTATATCCCAATGCTATTAACTAACTTTACCTTG
GCCTGGGCTAGGTCTCCATTGGAAATAATAACGGATGGCTGCTGCCACCTGGTGCATCAACTCAGCATGCCATGGTAACTGCAGCAGGTG
GCTCTTAGGCTGGGACACCAACACCAGCCACCTGCCCCATGTTCTGGTAGCCTCTTGGCACTGACCAGACTAGGAGCGCCTATGTTTGGC
ACAGATGCTGAGCCATGTGGTGGTTACTAGAGGAAAGGCCGACTCCCAGCTTCTGCTTCATTTCATCATGTGTACAATACAGATTAATAA
GCAGTAAGGAGCCAATGTATAAACAGCAGTTACATATTTTTTAAATTCCCCTTTCGTACAATTTAAAATAAAACATGTATACACTTCTCC
TCTCTTTCTACTGTACTTTAGCACCACAGGATATCAATTTTCAAGCCTATTATTACCTGATAGACATATATGAAGTTTGGAAGAAAAATA
AGGCAATTTGGTTTAAAATGTTGATAGTTTTAGCTTAATGCTCTAATGGAGAAAGCAAATCCTCACTCATATTATTAAATCATTTCAAGA

>90298_90298_2_TFDP2-COG5_TFDP2_chr3_141811903_ENST00000489671_COG5_chr7_106964966_ENST00000347053_length(amino acids)=443AA_BP=
MATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQHIQGNFNASGTTDLYVDLQHMEDDAQDIFIPKKPDYDPEKALKDSLQPYEAAYL
SKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNVAAVDTNLTLAVSKNVAKTIQLYSVKSEQLLSTQGDASQVIGPLTEGQRR
NVAVVNSLYKLHQSVTKAIHALMENAVQPLLTSVGDAIEAIIITMHQEDFSGSLSSSGKPDVPCSLYMKELQGFIARVMSDYFKHFECLD
FVFDNTEAIAQRAVELFIRHASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQASEHVASSPALGDVIPFS

--------------------------------------------------------------
>90298_90298_3_TFDP2-COG5_TFDP2_chr3_141811903_ENST00000489671_COG5_chr7_106964966_ENST00000393603_length(transcript)=4540nt_BP=513nt
AAAGCTCGCGCGGGGGAAGCGGGGCTGTAGCTGGGCAGGGAGAGGGCGGACGAAATCGGTAGCGATCTCGGCTGCGGCGCTGCCGCAGCT
GCCCGGCCCGCGGGGCGCGCCCTGACCCTTCATCTTTGGGCAGGCTCGAGGGCGCGCGCACGGTTGGCGTTCTGGGGCCTCAAACTCCTG
GGCCTTGACCGGGCAGGCCGCGTCTCCCCGGGTGTGAGTCCACCGGGACCCGGCCGCCGCCTAAGCGCGGGCGCCACAGAAGCGGCGGCG
CCCGAAGACGCGCTCCTGGCTCGGCCCGACAGCCTCGCTTGGCCGCCAGTTCTTCTGCAGCCGAAGGCGGTTGTTCTTTTAAAGAATTAT
TGAAGACGAAGGTTTTTTTCTTTTTATTTTTTTAATGGCTTTACAGAATCTTAAATAGAATACAGTTTGACATGACGGCAAAAAATGTTG
GTTTGACTTCCACAAATGCAGAAGTAAGAGGATTTATAGATCAGAATCTCAGTCCAACAAAAGGATGGACAACCGGAAATTTTCTACACA
TTTTGGAATTCAGTTACTCAGGCACTTTCTTCTCAATTTCATATGGCAACAAACTCTTCGATGTTTTTGAAGCAGGCATTTGAAGGAGAA
TACCCTAAATTATTACGTCTTTATAATGACTTATGGAAGCGTCTTCAACAATACAGTCAGCATATCCAAGGGAATTTTAATGCAAGTGGA
ACTACAGACCTCTATGTTGACCTACAACACATGGAAGATGATGCACAAGATATATTCATACCAAAAAAGCCAGATTATGATCCAGAAAAG
GCTTTGAAAGACTCACTACAACCCTATGAGGCTGCTTATCTATCAAAATCCTTATCTCGACTCTTCGATCCTATCAACTTGGTTTTTCCC
CCGGGTGGTCGTAATCCTCCTTCCTCTGATGAACTTGATGGTATTATTAAAACTATAGCAAGTGAACTAAATGTTGCTGCTGTTGATACA
AACCTCACATTAGCTGTGTCAAAAAATGTGGCAAAGACCATCCAGTTATACAGTGTAAAATCAGAGCAGCTTCTCTCCACACAAGGAGAT
GCAAGTCAGGTGATTGGGCCTCTTACTGAAGGACAGAGAAGAAATGTGGCAGTAGTGAATTCATTGTATAAGTTGCACCAATCAGTAACA
AAGGTTGTTTCCAGTCAGAGCTCATTCCCACTGGCAGCTGAGCAAACTATAATTTCAGCTCTAAAGGCTATTCATGCTCTTATGGAAAAT
GCTGTGCAACCCTTACTCACTTCTGTGGGAGATGCTATAGAGGCCATAATCATCACCATGCATCAAGAAGACTTTTCTGGGTCATTATCC
AGCTCAGGAAAACCTGATGTTCCTTGTTCTCTGTACATGAAGGAGCTACAAGGTTTCATTGCCAGAGTTATGAGTGACTATTTTAAACAC
TTTGAATGCTTGGATTTTGTCTTTGACAACACTGAGGCTATTGCCCAAAGAGCTGTTGAACTTTTTATCCGCCATGCCAGTCTCATAAGA
CCTCTTGGTGAAGGTGGGAAAATGCGACTTGCTGCTGATTTTGCACAGATGGAGTTGGCTGTGGGTCCATTCTGTAGACGAGTATCTGAT
TTAGGAAAGTCCTATCGGATGCTGAGATCATTCAGACCTCTGCTCTTCCAGGCAAGTGAACATGTAGCCAGTAGTCCTGCATTGGGGGAT
GTGATTCCGTTCAGCATCATTATTCAGTTTTTGTTCACGAGAGCACCCGCTGAACTGAAATCTCCTTTCCAGAGGGCAGAGTGGTCCCAC
ACACGCTTCTCTCAGTGGCTGGATGACCATCCATCTGAAAAGGACAGGCTCCTCCTCATCAGGTAAAGCCAGGTGCTCTGGGGGCACCCA
TCTGGTCTGGAAGCCCAAGGAGGGTGGGGATGCAAGAGAGGATGAAGGAGCAGTGCCTGGGGGCATGGACATGTGACTGCACCTTCCAGT
GGCGGGCCACCTCACTGCCTAGGCACGGGTGCTGGAGCAACCAGCAGTTGGAAATGTTGGCCACAACATCTTTTGCTTTCTTTCATTCCA
AACCTTCATATCCCTGATGTGCAATCCTGTGTCCCATGCAACCCTAAGGACCATGCATTTGTACCTTTGAAAATCATCATTTGCTATGAA
AAGTTTTGCCCTAGCTCCGCATCTTTTACTTCATTTTTATGTGCTGCAGTTACTGAATTGGTGGAACACAGATGTGAGTGAATTTTTAAA
AATACCCAAGTGCGAAACAGTTCTGAGGAGGAAACAAGAACAACCCAGCAGCCACTTGGATACCATGGCCCTCCAGTAGTGCCCCATGAA
TGCATTCACATACATACGCATGTGCTCTTGCCCACACGTGCACACACCCCCATGTACCCCAACCATGCCCAGGGTGGGGTGCTTTAACTG
TCATACATGGCTTATTAAGCAACACTCTTCCCTGCAACTGCTCTCACCATCACCAGAGACCTCTCAGCCACCAAACATTCCCATTTTTAC
CTTACCACTCTGTAGCTTTAGCTACAGTTGACCGCCATTTCCTTCTGTAAACTCATAAACTGGGACTCAGCACATTTTTATTGATGCTGA
GCTCACATTTTATCAGCATGGTAGGCCCTGGGCCAGGAACCGAGGATACGAAGTAAGCCGAGATATGGCCCTGTCCTCTCAGAGCTTGCA
TTACACCACAGCCATCTGTTTCTGTTCTAACTTCTCTGGCCATTTTTTTTTGTGTGTCATTTGCTGAATTATCTTCTTCTAGCCATTCCT
TAAATGCTATCATTTCCCATATTTTCTTCTTCTCATCCTGCCTCTGCCTTGGTTCCCAGGTGAGCTTGTCCAGACCCATGCCTCTAGTGC
CCCTTCTATACTTAAGAGCCCTCAGGTCTGTGACTGCCTCTGGATGGGGCCTTGGCCCAGTAAACTTGCTATCATATGTCACCACCCACA
GAAATCTCAACCCCAGAATGGTCAAAATAATTCTAATCTTTTCTCTCAAACCTTCTCATTCTCTTATACTCCCTGTCTTGGTTGGGAGGT
CACAATCACCTAACTAGCCAAGCCGGAAAACCTTTACATCATCATTCAACTCCTCTGTCATCCTTATTCCTCAAACCCACTCTGTTGCGT
CTCTAAAATAGCTCTTGAAGTCATTCTCAACTCTCCCAGGGGATCCCAATTCTGTTGGTCTGGGCCCACTGCACCCAGTGATCCTTTGTT
AGCCTGTGTCAGGTGATGAGTTGAGTTCCCTAAAGCCAGAGTGGGGCTGACATGATGAGGTGGTTCTAAACCACATGTGCACACAAGAAT
CATTTACATAGCTTGGAAAATTCCTAGTGCCCAGGTCTCTCACCCTTGCCTACCTCAGAATCTCCAGGGTAGGCCTGCTATCAGGATTTC
TCTATAGCTCCCCAAGAAGGTCCAGGGTGCAGCCAAGGGCGTGAACCCCTGCCATAGTGGGTCATATTTCAGTTAGGATGAAAGACTGCT
GAGGAAGCTATGACAGGTCAGTAAGAACCATCAGCCTGTCAGCTTTGTTTCCAGAAGTGACCCTGAGCCCTCAAGCTTGGTACCCACATC
CCACATGAGCCACTGGCCCTCTGGGCGTATGTGTGGATAAAGATTAGCTCGGACCCTGCTCTTTTTCCTTGCTTATCTGTTACTCAGCTA
TGAACATCTGACACAGAAATGGGAGAGGTTACCAGCCCCGGTGAATGTTCCTGGTAAAATCTGCCCTCGGGAAAGGCTTTGGATTTGGGT
GAGGAGTTTGGGCCTGGGCTAACACAGGGATTTGCAATGTCTGTGTGGATTATTTTTCCCGAGTCCCAAAGATTCACTCAGCTGCAACAC
ACTCAGTCGTCTTAAAAAGAGGATTCAGTTAATTGAACACGTTCATTTTTCTCATCTTAACAAGTTGGTCATTTTTGTCGTCTTAACAAG
TTGGAATGAGTTCATCCAAAACAGTTGTCCTGCTGTGTGTACATCACAAATCTGTTTTCTTTTGCTTCTCTTTAAAAATGTCTCCTGAGT
GATTTCATCAGCAGTGCTGTTGCTAAGCCTATATTTAGCAACTGAAAATCATGCTCAGAAATACTGTCATGCTTTTTTAAAAAGGCATAT
CCATCCCTCCACACATGGCTGATTCCAGAACCTTCATGCCCTTAGCAAAAAATTGAGCTGTCCTTCAGGGTTTCAAAAAAAGTACTGTAC
TCCTGCTGCACCCCAGGCTCTTGGCAAGGAGGGGACTTTTGTCCTAGAGAATGTTCTTTCTTATGTATTATTGCAAAACAATTTTGTTCT
TGCATACTGAAGCATCACTGGATGAATTTCTTTCCCCTGTAGACAAACCGAGGGTGAGTATTGCTCTTTAAATGTCAGTAAATTTGTTTT
AGCTTCTGGGGCAAACCTTGTTGTATACTCATTCTGTTCCTCCCAGCATAATATGTTAGGTTGTCATAAAATAGGGCAAATTGAGGATAG

>90298_90298_3_TFDP2-COG5_TFDP2_chr3_141811903_ENST00000489671_COG5_chr7_106964966_ENST00000393603_length(amino acids)=427AA_BP=
MATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQHIQGNFNASGTTDLYVDLQHMEDDAQDIFIPKKPDYDPEKALKDSLQPYEAAYL
SKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNVAAVDTNLTLAVSKNVAKTIQLYSVKSEQLLSTQGDASQVIGPLTEGQRR
NVAVVNSLYKLHQSVTKVVSSQSSFPLAAEQTIISALKAIHALMENAVQPLLTSVGDAIEAIIITMHQEDFSGSLSSSGKPDVPCSLYMK
ELQGFIARVMSDYFKHFECLDFVFDNTEAIAQRAVELFIRHASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for TFDP2-COG5

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Hgene	TFDP2	chr3:141811903	chr7:106964966	ENST00000310282	-	1	10	60_82	0	387.0	CEBPA
Hgene	TFDP2	chr3:141811903	chr7:106964966	ENST00000397991	-	1	10	60_82	0.0	419.0	CEBPA
Hgene	TFDP2	chr3:141811903	chr7:106964966	ENST00000467072	-	3	14	60_82	0	387.0	CEBPA
Hgene	TFDP2	chr3:141811903	chr7:106964966	ENST00000477292	-	1	8	60_82	0	311.0	CEBPA
Hgene	TFDP2	chr3:141811903	chr7:106964966	ENST00000479040	-	1	10	60_82	0	386.0	CEBPA
Hgene	TFDP2	chr3:141811903	chr7:106964966	ENST00000486111	-	1	11	60_82	0	387.0	CEBPA
Hgene	TFDP2	chr3:141811903	chr7:106964966	ENST00000489671	-	3	13	60_82	27.333333333333332	447.0	CEBPA
Hgene	TFDP2	chr3:141811903	chr7:106964966	ENST00000495310	-	1	10	60_82	0	350.0	CEBPA
Hgene	TFDP2	chr3:141811903	chr7:106964966	ENST00000499676	-	1	13	60_82	0	387.0	CEBPA

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for TFDP2-COG5

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for TFDP2-COG5

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source