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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TFE3-PRCC (FusionGDB2 ID:90319)

Fusion Gene Summary for TFE3-PRCC

check button Fusion gene summary
Fusion gene informationFusion gene name: TFE3-PRCC
Fusion gene ID: 90319
HgeneTgene
Gene symbol

TFE3

PRCC

Gene ID

7030

5546

Gene nametranscription factor binding to IGHM enhancer 3proline rich mitotic checkpoint control factor
SynonymsRCCP2|RCCX1|TFEA|bHLHe33RCCP1|TPRC
Cytomap

Xp11.23

1q23.1

Type of geneprotein-codingprotein-coding
Descriptiontranscription factor E3class E basic helix-loop-helix protein 33transcription factor E family, member Atranscription factor for IgH enhancertranscription factor for immunoglobulin heavy-chain enhancer 3proline-rich protein PRCCPRCC, proline rich mitotic checkpoint control factorpapillary renal cell carcinoma (translocation-associated)papillary renal cell carcinoma translocation-associated gene protein
Modification date2020032720200313
UniProtAcc.

Q92733

Ensembl transtripts involved in fusion geneENST00000315869, ENST00000487451, 
ENST00000491853, ENST00000271526, 
ENST00000353233, 
Fusion gene scores* DoF score9 X 12 X 6=6487 X 10 X 4=280
# samples 1212
** MAII scorelog2(12/648*10)=-2.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/280*10)=-1.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TFE3 [Title/Abstract] AND PRCC [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPRCC(156738031)-TFE3(48895967), # samples:12
TFE3(48896632)-PRCC(156752074), # samples:3
Anticipated loss of major functional domain due to fusion event.PRCC-TFE3 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
PRCC-TFE3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
PRCC-TFE3 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
PRCC-TFE3 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
PRCC-TFE3 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePRCC

GO:0007093

mitotic cell cycle checkpoint

11717438


check buttonFusion gene breakpoints across TFE3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PRCC (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4KIRPTCGA-BQ-5882-01ATFE3chrX

48896632

-PRCCchr1

156752074

+
ChimerDB4KIRPTCGA-BQ-5882TFE3chrX

48896631

-PRCCchr1

156752073

+
ChimerDB4KIRPTCGA-BQ-5882TFE3chrX

48896632

-PRCCchr1

156752074

+
ChimerDB4KIRPTCGA-BQ-5887-01ATFE3chrX

48896632

-PRCCchr1

156756400

+
ChimerDB4KIRPTCGA-BQ-5887TFE3chrX

48896631

-PRCCchr1

156756399

+
ChimerKB3..TFE3chrX

156738031

-PRCCchr1

48895967

+


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Fusion Gene ORF analysis for TFE3-PRCC

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000315869ENST00000491853TFE3chrX

48896632

-PRCCchr1

156752074

+
5CDS-3UTRENST00000315869ENST00000491853TFE3chrX

48896631

-PRCCchr1

156752073

+
5CDS-3UTRENST00000315869ENST00000491853TFE3chrX

48896632

-PRCCchr1

156756400

+
5CDS-3UTRENST00000315869ENST00000491853TFE3chrX

48896631

-PRCCchr1

156756399

+
5UTR-3CDSENST00000487451ENST00000271526TFE3chrX

48896632

-PRCCchr1

156752074

+
5UTR-3CDSENST00000487451ENST00000271526TFE3chrX

48896631

-PRCCchr1

156752073

+
5UTR-3CDSENST00000487451ENST00000271526TFE3chrX

48896632

-PRCCchr1

156756400

+
5UTR-3CDSENST00000487451ENST00000271526TFE3chrX

48896631

-PRCCchr1

156756399

+
5UTR-3CDSENST00000487451ENST00000353233TFE3chrX

48896632

-PRCCchr1

156752074

+
5UTR-3CDSENST00000487451ENST00000353233TFE3chrX

48896631

-PRCCchr1

156752073

+
5UTR-3CDSENST00000487451ENST00000353233TFE3chrX

48896632

-PRCCchr1

156756400

+
5UTR-3CDSENST00000487451ENST00000353233TFE3chrX

48896631

-PRCCchr1

156756399

+
5UTR-3UTRENST00000487451ENST00000491853TFE3chrX

48896632

-PRCCchr1

156752074

+
5UTR-3UTRENST00000487451ENST00000491853TFE3chrX

48896631

-PRCCchr1

156752073

+
5UTR-3UTRENST00000487451ENST00000491853TFE3chrX

48896632

-PRCCchr1

156756400

+
5UTR-3UTRENST00000487451ENST00000491853TFE3chrX

48896631

-PRCCchr1

156756399

+
In-frameENST00000315869ENST00000271526TFE3chrX

48896632

-PRCCchr1

156752074

+
In-frameENST00000315869ENST00000271526TFE3chrX

48896631

-PRCCchr1

156752073

+
In-frameENST00000315869ENST00000271526TFE3chrX

48896632

-PRCCchr1

156756400

+
In-frameENST00000315869ENST00000271526TFE3chrX

48896631

-PRCCchr1

156756399

+
In-frameENST00000315869ENST00000353233TFE3chrX

48896632

-PRCCchr1

156752074

+
In-frameENST00000315869ENST00000353233TFE3chrX

48896631

-PRCCchr1

156752073

+
In-frameENST00000315869ENST00000353233TFE3chrX

48896632

-PRCCchr1

156756400

+
In-frameENST00000315869ENST00000353233TFE3chrX

48896631

-PRCCchr1

156756399

+
intron-intronENST00000315869ENST00000271526TFE3chrX

156738031

-PRCCchr1

48895967

+
intron-intronENST00000315869ENST00000353233TFE3chrX

156738031

-PRCCchr1

48895967

+
intron-intronENST00000315869ENST00000491853TFE3chrX

156738031

-PRCCchr1

48895967

+
intron-intronENST00000487451ENST00000271526TFE3chrX

156738031

-PRCCchr1

48895967

+
intron-intronENST00000487451ENST00000353233TFE3chrX

156738031

-PRCCchr1

48895967

+
intron-intronENST00000487451ENST00000491853TFE3chrX

156738031

-PRCCchr1

48895967

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000315869TFE3chrX48896632-ENST00000271526PRCCchr1156752074+21577942601801513
ENST00000315869TFE3chrX48896632-ENST00000353233PRCCchr1156752074+20567942601705481
ENST00000315869TFE3chrX48896632-ENST00000271526PRCCchr1156756400+21097942601753497
ENST00000315869TFE3chrX48896632-ENST00000353233PRCCchr1156756400+20087942601657465
ENST00000315869TFE3chrX48896631-ENST00000271526PRCCchr1156752073+21577942601801513
ENST00000315869TFE3chrX48896631-ENST00000353233PRCCchr1156752073+20567942601705481
ENST00000315869TFE3chrX48896631-ENST00000271526PRCCchr1156756399+21097942601753497
ENST00000315869TFE3chrX48896631-ENST00000353233PRCCchr1156756399+20087942601657465

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000315869ENST00000271526TFE3chrX48896632-PRCCchr1156752074+0.0079032030.9920968
ENST00000315869ENST00000353233TFE3chrX48896632-PRCCchr1156752074+0.009575930.9904241
ENST00000315869ENST00000271526TFE3chrX48896632-PRCCchr1156756400+0.0098825050.9901175
ENST00000315869ENST00000353233TFE3chrX48896632-PRCCchr1156756400+0.0125390860.9874609
ENST00000315869ENST00000271526TFE3chrX48896631-PRCCchr1156752073+0.0079032030.9920968
ENST00000315869ENST00000353233TFE3chrX48896631-PRCCchr1156752073+0.009575930.9904241
ENST00000315869ENST00000271526TFE3chrX48896631-PRCCchr1156756399+0.0098825050.9901175
ENST00000315869ENST00000353233TFE3chrX48896631-PRCCchr1156756399+0.0125390860.9874609

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Fusion Genomic Features for TFE3-PRCC


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TFE3chrX48896631-PRCCchr1156756399+0.0002856120.9997143
TFE3chrX48896631-PRCCchr1156756399+0.0002856120.9997143
TFE3chrX48896631-PRCCchr1156752073+1.22E-060.9999988
TFE3chrX48896631-PRCCchr1156752073+1.22E-060.9999988
TFE3chrX48896631-PRCCchr1156756399+0.0002856120.9997143
TFE3chrX48896631-PRCCchr1156756399+0.0002856120.9997143
TFE3chrX48896631-PRCCchr1156752073+1.22E-060.9999988
TFE3chrX48896631-PRCCchr1156752073+1.22E-060.9999988

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for TFE3-PRCC


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrX:156738031/chr1:48895967)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.PRCC

Q92733

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: May regulate cell cycle progression through interaction with MAD2L2. {ECO:0000269|PubMed:11717438}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePRCCchrX:48896631chr1:156752073ENST0000027152607235_239156492.0Compositional biasNote=Poly-Thr
TgenePRCCchrX:48896631chr1:156756399ENST0000027152617235_239172492.0Compositional biasNote=Poly-Thr
TgenePRCCchrX:48896632chr1:156752074ENST0000027152607235_239156492.0Compositional biasNote=Poly-Thr
TgenePRCCchrX:48896632chr1:156756400ENST0000027152617235_239172492.0Compositional biasNote=Poly-Thr

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTFE3chrX:48896631chr1:156752073ENST00000315869-310346_399178576.0DomainbHLH
HgeneTFE3chrX:48896631chr1:156756399ENST00000315869-310346_399178576.0DomainbHLH
HgeneTFE3chrX:48896632chr1:156752074ENST00000315869-310346_399178576.0DomainbHLH
HgeneTFE3chrX:48896632chr1:156756400ENST00000315869-310346_399178576.0DomainbHLH
HgeneTFE3chrX:48896631chr1:156752073ENST00000315869-310260_271178576.0RegionStrong transcription activation domain
HgeneTFE3chrX:48896631chr1:156752073ENST00000315869-310409_430178576.0RegionNote=Leucine-zipper
HgeneTFE3chrX:48896631chr1:156756399ENST00000315869-310260_271178576.0RegionStrong transcription activation domain
HgeneTFE3chrX:48896631chr1:156756399ENST00000315869-310409_430178576.0RegionNote=Leucine-zipper
HgeneTFE3chrX:48896632chr1:156752074ENST00000315869-310260_271178576.0RegionStrong transcription activation domain
HgeneTFE3chrX:48896632chr1:156752074ENST00000315869-310409_430178576.0RegionNote=Leucine-zipper
HgeneTFE3chrX:48896632chr1:156756400ENST00000315869-310260_271178576.0RegionStrong transcription activation domain
HgeneTFE3chrX:48896632chr1:156756400ENST00000315869-310409_430178576.0RegionNote=Leucine-zipper
TgenePRCCchrX:48896631chr1:156752073ENST000002715260718_25156492.0Compositional biasNote=Poly-Glu
TgenePRCCchrX:48896631chr1:156752073ENST000002715260752_55156492.0Compositional biasNote=Poly-Pro
TgenePRCCchrX:48896631chr1:156752073ENST000002715260779_84156492.0Compositional biasNote=Poly-Pro
TgenePRCCchrX:48896631chr1:156752073ENST000002715260791_94156492.0Compositional biasNote=Poly-Pro
TgenePRCCchrX:48896631chr1:156756399ENST000002715261718_25172492.0Compositional biasNote=Poly-Glu
TgenePRCCchrX:48896631chr1:156756399ENST000002715261752_55172492.0Compositional biasNote=Poly-Pro
TgenePRCCchrX:48896631chr1:156756399ENST000002715261779_84172492.0Compositional biasNote=Poly-Pro
TgenePRCCchrX:48896631chr1:156756399ENST000002715261791_94172492.0Compositional biasNote=Poly-Pro
TgenePRCCchrX:48896632chr1:156752074ENST000002715260718_25156492.0Compositional biasNote=Poly-Glu
TgenePRCCchrX:48896632chr1:156752074ENST000002715260752_55156492.0Compositional biasNote=Poly-Pro
TgenePRCCchrX:48896632chr1:156752074ENST000002715260779_84156492.0Compositional biasNote=Poly-Pro
TgenePRCCchrX:48896632chr1:156752074ENST000002715260791_94156492.0Compositional biasNote=Poly-Pro
TgenePRCCchrX:48896632chr1:156756400ENST000002715261718_25172492.0Compositional biasNote=Poly-Glu
TgenePRCCchrX:48896632chr1:156756400ENST000002715261752_55172492.0Compositional biasNote=Poly-Pro
TgenePRCCchrX:48896632chr1:156756400ENST000002715261779_84172492.0Compositional biasNote=Poly-Pro
TgenePRCCchrX:48896632chr1:156756400ENST000002715261791_94172492.0Compositional biasNote=Poly-Pro


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Fusion Gene Sequence for TFE3-PRCC


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>90319_90319_1_TFE3-PRCC_TFE3_chrX_48896631_ENST00000315869_PRCC_chr1_156752073_ENST00000271526_length(transcript)=2157nt_BP=794nt
GGGAGGAGGGGGAAGAAGACGAGGGGGAGGAGGGCGGTCGTCCGGGGTTAGGTTGAGGGGGGGCGTCGGTCCGTTCTGGGCGGGGGATGA
CTCACAGCCCATCCCATCTCCCAGACGCCGCCCGCCCGCGCAGTGCTAGCTCCATGGCTTAGCGGAGGAGGCGGCAGTGGCGAGCTGGGG
GGAGGGGGGACTCTTATTTTGTTAGGGGGACCGGGCCGAGGCCCGACCGGCCTGGCAGGGCTCGCCCGGGGCCGGGCGTCATGTCTCATG
CGGCCGAACCAGCTCGGGATGGCGTAGAGGCCAGCGCGGAGGGCCCTCGAGCCGTGTTCGTGCTGTTGGAGGAGCGCAGGCCGGCCGACT
CGGCTCAGCTGCTCAGCCTGAACTCTTTGCTTCCGGAATCCGGGATTGTTGCTGACATAGAATTAGAAAACGTCCTTGATCCTGACAGCT
TCTACGAGCTCAAAAGCCAACCCTTACCCCTTCGCTCAAGCCTCCCAATATCACTGCAGGCCACACCAGCCACCCCAGCTACACTCTCTG
CATCGTCTTCTGCAGGGGGCTCCAGGACCCCTGCCATGTCGTCATCTTCTTCATCGAGGGTCTTGCTGCGGCAGCAGCTAATGCGGGCCC
AGGCGCAGGAGCAGGAGAGGCGTGAGCGTCGGGAACAGGCCGCCGCGGCTCCCTTCCCCAGTCCTGCACCTGCCTCTCCTGCCATCTCTG
TGGTTGGCGTCTCTGCTGGGGGCCACACATTGAGCCGTCCACCCCCTGCTCAGGTGCCCAGGGAGGTGCTCAAGTCAGATTCTGAGGAAG
ATGAACCCACAAAGAAGAAAACTATCCTTCAGGGATCCAGTGAGGGGACTGGTTTGTCTGCCTTGCTTCCCCAACCTAAAAACCTGACTG
TGAAAGAGACTAACAGGTTGCTCCTGCCCCATGCCTTCTCCCGCAAACCCTCGGATGGCTCCCCTGATACTAAGCCCTCCAGACTGGCTT
CTAAGACCAAGACTTCCTCTCTTGCCCCTGTTGTGGGCACCACAACCACCACTCCGTCGCCCTCTGCTATCAAGGCTGCTGCCAAGAGTG
CTGCCCTGCAGGTGACAAAGCAGATCACGCAGGAAGAAGACGACAGTGATGAGGAAGTAGCCCCCGAAAACTTTTTCTCCCTCCCTGAAA
AGGCTGAGCCACCTGGAGTTGAGCCATACCCTTACCCCATCCCCACTGTCCCTGAAGAGCTGCCTCCAGGCACGGAACCAGAGCCGGCTT
TCCAGGACGATGCAGCCAATGCCCCCCTTGAATTCAAGATGGCAGCAGGTTCAAGTGGGGCCCCTTGGATGCCTAAGCCTGGGGACGACT
ACAGCTACAATCAGTTTTCCACATATGGCGATGCCAATGCCGCTGGTGCTTATTATCAGGATTATTACAGTGGTGGCTACTATCCTGCAC
AGGACCCGGCCCTGGTCCCCCCCCAGGAAATTGCCCCAGATGCCTCCTTCATCGATGACGAAGCATTTAAGCGGCTGCAGGGCAAGAGGA
ACCGAGGGAGAGAAGAAATCAACTTTGTGGAGATCAAAGGTGATGACCAGCTCAGTGGGGCCCAGCAATGGATGACTAAGTCATTGACAG
AAGAGAAAACCATGAAGTCATTCAGCAAAAAGAAAGGTGAGCAGCCAACAGGCCAGCAGCGGCGGAAACACCAGATCACATATCTTATTC
ATCAGGCCAAGGAGCGGGAGCTGGAACTGAAGAACACCTGGTCAGAGAACAAGCTCAGCCGCCGTCAGACCCAAGCCAAATATGGATTCT
AGGGCTCTGGAACTGATTGCTCCCAGGATCTCCTGCCAGCCCAGCTGGCCTGGCCCCCAGCTTCACCTCTGGGACCCCAGCTGCTCTAAG
CCCAGGATCTCTTTCCCCAAGGACCCAGCCCTCGCCTCTGCGAGAATGAACATATTTGATAGATTTTTCTTAACAAGTTAGAAAATTCAG
CTCCTTTCTGTCCTGGAGCTAGCAAAGACTTGTGTGATGCCTCCGAAGGGGCTCTGAGTTCTGGGGTGGGAGTTTTGCTCTCTGTCAGGT

>90319_90319_1_TFE3-PRCC_TFE3_chrX_48896631_ENST00000315869_PRCC_chr1_156752073_ENST00000271526_length(amino acids)=513AA_BP=57
MSHAAEPARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELENVLDPDSFYELKSQPLPLRSSLPISLQATPATPA
TLSASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKSD
SEEDEPTKKKTILQGSSEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAA
AKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKP
GDDYSYNQFSTYGDANAAGAYYQDYYSGGYYPAQDPALVPPQEIAPDASFIDDEAFKRLQGKRNRGREEINFVEIKGDDQLSGAQQWMTK

--------------------------------------------------------------
>90319_90319_2_TFE3-PRCC_TFE3_chrX_48896631_ENST00000315869_PRCC_chr1_156752073_ENST00000353233_length(transcript)=2056nt_BP=794nt
GGGAGGAGGGGGAAGAAGACGAGGGGGAGGAGGGCGGTCGTCCGGGGTTAGGTTGAGGGGGGGCGTCGGTCCGTTCTGGGCGGGGGATGA
CTCACAGCCCATCCCATCTCCCAGACGCCGCCCGCCCGCGCAGTGCTAGCTCCATGGCTTAGCGGAGGAGGCGGCAGTGGCGAGCTGGGG
GGAGGGGGGACTCTTATTTTGTTAGGGGGACCGGGCCGAGGCCCGACCGGCCTGGCAGGGCTCGCCCGGGGCCGGGCGTCATGTCTCATG
CGGCCGAACCAGCTCGGGATGGCGTAGAGGCCAGCGCGGAGGGCCCTCGAGCCGTGTTCGTGCTGTTGGAGGAGCGCAGGCCGGCCGACT
CGGCTCAGCTGCTCAGCCTGAACTCTTTGCTTCCGGAATCCGGGATTGTTGCTGACATAGAATTAGAAAACGTCCTTGATCCTGACAGCT
TCTACGAGCTCAAAAGCCAACCCTTACCCCTTCGCTCAAGCCTCCCAATATCACTGCAGGCCACACCAGCCACCCCAGCTACACTCTCTG
CATCGTCTTCTGCAGGGGGCTCCAGGACCCCTGCCATGTCGTCATCTTCTTCATCGAGGGTCTTGCTGCGGCAGCAGCTAATGCGGGCCC
AGGCGCAGGAGCAGGAGAGGCGTGAGCGTCGGGAACAGGCCGCCGCGGCTCCCTTCCCCAGTCCTGCACCTGCCTCTCCTGCCATCTCTG
TGGTTGGCGTCTCTGCTGGGGGCCACACATTGAGCCGTCCACCCCCTGCTCAGGTGCCCAGGGAGGTGCTCAAGTCAGATTCTGAGGAAG
ATGAACCCACAAAGAAGAAAACTATCCTTCAGGGATCCAGTGAGGGGACTGGTTTGTCTGCCTTGCTTCCCCAACCTAAAAACCTGACTG
TGAAAGAGACTAACAGGTTGCTCCTGCCCCATGCCTTCTCCCGCAAACCCTCGGATGGCTCCCCTGATACTAAGCCCTCCAGACTGGCTT
CTAAGACCAAGACTTCCTCTCTTGCCCCTGTTGTGGGCACCACAACCACCACTCCGTCGCCCTCTGCTATCAAGGCTGCTGCCAAGAGTG
CTGCCCTGCAGGTGACAAAGCAGATCACGCAGGAAGAAGACGACAGTGATGAGGAAGTAGCCCCCGAAAACTTTTTCTCCCTCCCTGAAA
AGGCTGAGCCACCTGGAGTTGAGCCATACCCTTACCCCATCCCCACTGTCCCTGAAGAGCTGCCTCCAGGCACGGAACCAGAGCCGGCTT
TCCAGGACGATGCAGCCAATGCCCCCCTTGAATTCAAGATGGCAGCAGGTTCAAGTGGGGCCCCTTGGATGCCTAAGCCTGGGGACGACT
ACAGCTACAATCAGTTTTCCACATATGGCGATGCCAATGCCGCTGGTGCTTATTATCAGTTTAAGCGGCTGCAGGGCAAGAGGAACCGAG
GGAGAGAAGAAATCAACTTTGTGGAGATCAAAGGTGATGACCAGCTCAGTGGGGCCCAGCAATGGATGACTAAGTCATTGACAGAAGAGA
AAACCATGAAGTCATTCAGCAAAAAGAAAGGTGAGCAGCCAACAGGCCAGCAGCGGCGGAAACACCAGATCACATATCTTATTCATCAGG
CCAAGGAGCGGGAGCTGGAACTGAAGAACACCTGGTCAGAGAACAAGCTCAGCCGCCGTCAGACCCAAGCCAAATATGGATTCTAGGGCT
CTGGAACTGATTGCTCCCAGGATCTCCTGCCAGCCCAGCTGGCCTGGCCCCCAGCTTCACCTCTGGGACCCCAGCTGCTCTAAGCCCAGG
ATCTCTTTCCCCAAGGACCCAGCCCTCGCCTCTGCGAGAATGAACATATTTGATAGATTTTTCTTAACAAGTTAGAAAATTCAGCTCCTT
TCTGTCCTGGAGCTAGCAAAGACTTGTGTGATGCCTCCGAAGGGGCTCTGAGTTCTGGGGTGGGAGTTTTGCTCTCTGTCAGGTGTGATA

>90319_90319_2_TFE3-PRCC_TFE3_chrX_48896631_ENST00000315869_PRCC_chr1_156752073_ENST00000353233_length(amino acids)=481AA_BP=57
MSHAAEPARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELENVLDPDSFYELKSQPLPLRSSLPISLQATPATPA
TLSASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKSD
SEEDEPTKKKTILQGSSEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAA
AKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKP
GDDYSYNQFSTYGDANAAGAYYQFKRLQGKRNRGREEINFVEIKGDDQLSGAQQWMTKSLTEEKTMKSFSKKKGEQPTGQQRRKHQITYL

--------------------------------------------------------------
>90319_90319_3_TFE3-PRCC_TFE3_chrX_48896631_ENST00000315869_PRCC_chr1_156756399_ENST00000271526_length(transcript)=2109nt_BP=794nt
GGGAGGAGGGGGAAGAAGACGAGGGGGAGGAGGGCGGTCGTCCGGGGTTAGGTTGAGGGGGGGCGTCGGTCCGTTCTGGGCGGGGGATGA
CTCACAGCCCATCCCATCTCCCAGACGCCGCCCGCCCGCGCAGTGCTAGCTCCATGGCTTAGCGGAGGAGGCGGCAGTGGCGAGCTGGGG
GGAGGGGGGACTCTTATTTTGTTAGGGGGACCGGGCCGAGGCCCGACCGGCCTGGCAGGGCTCGCCCGGGGCCGGGCGTCATGTCTCATG
CGGCCGAACCAGCTCGGGATGGCGTAGAGGCCAGCGCGGAGGGCCCTCGAGCCGTGTTCGTGCTGTTGGAGGAGCGCAGGCCGGCCGACT
CGGCTCAGCTGCTCAGCCTGAACTCTTTGCTTCCGGAATCCGGGATTGTTGCTGACATAGAATTAGAAAACGTCCTTGATCCTGACAGCT
TCTACGAGCTCAAAAGCCAACCCTTACCCCTTCGCTCAAGCCTCCCAATATCACTGCAGGCCACACCAGCCACCCCAGCTACACTCTCTG
CATCGTCTTCTGCAGGGGGCTCCAGGACCCCTGCCATGTCGTCATCTTCTTCATCGAGGGTCTTGCTGCGGCAGCAGCTAATGCGGGCCC
AGGCGCAGGAGCAGGAGAGGCGTGAGCGTCGGGAACAGGCCGCCGCGGCTCCCTTCCCCAGTCCTGCACCTGCCTCTCCTGCCATCTCTG
TGGTTGGCGTCTCTGCTGGGGGCCACACATTGAGCCGTCCACCCCCTGCTCAGGTGCCCAGGGAGGTGCTCAAGGGATCCAGTGAGGGGA
CTGGTTTGTCTGCCTTGCTTCCCCAACCTAAAAACCTGACTGTGAAAGAGACTAACAGGTTGCTCCTGCCCCATGCCTTCTCCCGCAAAC
CCTCGGATGGCTCCCCTGATACTAAGCCCTCCAGACTGGCTTCTAAGACCAAGACTTCCTCTCTTGCCCCTGTTGTGGGCACCACAACCA
CCACTCCGTCGCCCTCTGCTATCAAGGCTGCTGCCAAGAGTGCTGCCCTGCAGGTGACAAAGCAGATCACGCAGGAAGAAGACGACAGTG
ATGAGGAAGTAGCCCCCGAAAACTTTTTCTCCCTCCCTGAAAAGGCTGAGCCACCTGGAGTTGAGCCATACCCTTACCCCATCCCCACTG
TCCCTGAAGAGCTGCCTCCAGGCACGGAACCAGAGCCGGCTTTCCAGGACGATGCAGCCAATGCCCCCCTTGAATTCAAGATGGCAGCAG
GTTCAAGTGGGGCCCCTTGGATGCCTAAGCCTGGGGACGACTACAGCTACAATCAGTTTTCCACATATGGCGATGCCAATGCCGCTGGTG
CTTATTATCAGGATTATTACAGTGGTGGCTACTATCCTGCACAGGACCCGGCCCTGGTCCCCCCCCAGGAAATTGCCCCAGATGCCTCCT
TCATCGATGACGAAGCATTTAAGCGGCTGCAGGGCAAGAGGAACCGAGGGAGAGAAGAAATCAACTTTGTGGAGATCAAAGGTGATGACC
AGCTCAGTGGGGCCCAGCAATGGATGACTAAGTCATTGACAGAAGAGAAAACCATGAAGTCATTCAGCAAAAAGAAAGGTGAGCAGCCAA
CAGGCCAGCAGCGGCGGAAACACCAGATCACATATCTTATTCATCAGGCCAAGGAGCGGGAGCTGGAACTGAAGAACACCTGGTCAGAGA
ACAAGCTCAGCCGCCGTCAGACCCAAGCCAAATATGGATTCTAGGGCTCTGGAACTGATTGCTCCCAGGATCTCCTGCCAGCCCAGCTGG
CCTGGCCCCCAGCTTCACCTCTGGGACCCCAGCTGCTCTAAGCCCAGGATCTCTTTCCCCAAGGACCCAGCCCTCGCCTCTGCGAGAATG
AACATATTTGATAGATTTTTCTTAACAAGTTAGAAAATTCAGCTCCTTTCTGTCCTGGAGCTAGCAAAGACTTGTGTGATGCCTCCGAAG
GGGCTCTGAGTTCTGGGGTGGGAGTTTTGCTCTCTGTCAGGTGTGATAAAATGTTGAACCCTCCCCACCACCACTTTTTTTTTTTTAAAC

>90319_90319_3_TFE3-PRCC_TFE3_chrX_48896631_ENST00000315869_PRCC_chr1_156756399_ENST00000271526_length(amino acids)=497AA_BP=57
MSHAAEPARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELENVLDPDSFYELKSQPLPLRSSLPISLQATPATPA
TLSASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKGS
SEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAAAKSAALQVTKQITQEE
DDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDAN
AAGAYYQDYYSGGYYPAQDPALVPPQEIAPDASFIDDEAFKRLQGKRNRGREEINFVEIKGDDQLSGAQQWMTKSLTEEKTMKSFSKKKG

--------------------------------------------------------------
>90319_90319_4_TFE3-PRCC_TFE3_chrX_48896631_ENST00000315869_PRCC_chr1_156756399_ENST00000353233_length(transcript)=2008nt_BP=794nt
GGGAGGAGGGGGAAGAAGACGAGGGGGAGGAGGGCGGTCGTCCGGGGTTAGGTTGAGGGGGGGCGTCGGTCCGTTCTGGGCGGGGGATGA
CTCACAGCCCATCCCATCTCCCAGACGCCGCCCGCCCGCGCAGTGCTAGCTCCATGGCTTAGCGGAGGAGGCGGCAGTGGCGAGCTGGGG
GGAGGGGGGACTCTTATTTTGTTAGGGGGACCGGGCCGAGGCCCGACCGGCCTGGCAGGGCTCGCCCGGGGCCGGGCGTCATGTCTCATG
CGGCCGAACCAGCTCGGGATGGCGTAGAGGCCAGCGCGGAGGGCCCTCGAGCCGTGTTCGTGCTGTTGGAGGAGCGCAGGCCGGCCGACT
CGGCTCAGCTGCTCAGCCTGAACTCTTTGCTTCCGGAATCCGGGATTGTTGCTGACATAGAATTAGAAAACGTCCTTGATCCTGACAGCT
TCTACGAGCTCAAAAGCCAACCCTTACCCCTTCGCTCAAGCCTCCCAATATCACTGCAGGCCACACCAGCCACCCCAGCTACACTCTCTG
CATCGTCTTCTGCAGGGGGCTCCAGGACCCCTGCCATGTCGTCATCTTCTTCATCGAGGGTCTTGCTGCGGCAGCAGCTAATGCGGGCCC
AGGCGCAGGAGCAGGAGAGGCGTGAGCGTCGGGAACAGGCCGCCGCGGCTCCCTTCCCCAGTCCTGCACCTGCCTCTCCTGCCATCTCTG
TGGTTGGCGTCTCTGCTGGGGGCCACACATTGAGCCGTCCACCCCCTGCTCAGGTGCCCAGGGAGGTGCTCAAGGGATCCAGTGAGGGGA
CTGGTTTGTCTGCCTTGCTTCCCCAACCTAAAAACCTGACTGTGAAAGAGACTAACAGGTTGCTCCTGCCCCATGCCTTCTCCCGCAAAC
CCTCGGATGGCTCCCCTGATACTAAGCCCTCCAGACTGGCTTCTAAGACCAAGACTTCCTCTCTTGCCCCTGTTGTGGGCACCACAACCA
CCACTCCGTCGCCCTCTGCTATCAAGGCTGCTGCCAAGAGTGCTGCCCTGCAGGTGACAAAGCAGATCACGCAGGAAGAAGACGACAGTG
ATGAGGAAGTAGCCCCCGAAAACTTTTTCTCCCTCCCTGAAAAGGCTGAGCCACCTGGAGTTGAGCCATACCCTTACCCCATCCCCACTG
TCCCTGAAGAGCTGCCTCCAGGCACGGAACCAGAGCCGGCTTTCCAGGACGATGCAGCCAATGCCCCCCTTGAATTCAAGATGGCAGCAG
GTTCAAGTGGGGCCCCTTGGATGCCTAAGCCTGGGGACGACTACAGCTACAATCAGTTTTCCACATATGGCGATGCCAATGCCGCTGGTG
CTTATTATCAGTTTAAGCGGCTGCAGGGCAAGAGGAACCGAGGGAGAGAAGAAATCAACTTTGTGGAGATCAAAGGTGATGACCAGCTCA
GTGGGGCCCAGCAATGGATGACTAAGTCATTGACAGAAGAGAAAACCATGAAGTCATTCAGCAAAAAGAAAGGTGAGCAGCCAACAGGCC
AGCAGCGGCGGAAACACCAGATCACATATCTTATTCATCAGGCCAAGGAGCGGGAGCTGGAACTGAAGAACACCTGGTCAGAGAACAAGC
TCAGCCGCCGTCAGACCCAAGCCAAATATGGATTCTAGGGCTCTGGAACTGATTGCTCCCAGGATCTCCTGCCAGCCCAGCTGGCCTGGC
CCCCAGCTTCACCTCTGGGACCCCAGCTGCTCTAAGCCCAGGATCTCTTTCCCCAAGGACCCAGCCCTCGCCTCTGCGAGAATGAACATA
TTTGATAGATTTTTCTTAACAAGTTAGAAAATTCAGCTCCTTTCTGTCCTGGAGCTAGCAAAGACTTGTGTGATGCCTCCGAAGGGGCTC
TGAGTTCTGGGGTGGGAGTTTTGCTCTCTGTCAGGTGTGATAAAATGTTGAACCCTCCCCACCACCACTTTTTTTTTTTTAAACCAGGGA

>90319_90319_4_TFE3-PRCC_TFE3_chrX_48896631_ENST00000315869_PRCC_chr1_156756399_ENST00000353233_length(amino acids)=465AA_BP=57
MSHAAEPARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELENVLDPDSFYELKSQPLPLRSSLPISLQATPATPA
TLSASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKGS
SEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAAAKSAALQVTKQITQEE
DDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDAN
AAGAYYQFKRLQGKRNRGREEINFVEIKGDDQLSGAQQWMTKSLTEEKTMKSFSKKKGEQPTGQQRRKHQITYLIHQAKERELELKNTWS

--------------------------------------------------------------
>90319_90319_5_TFE3-PRCC_TFE3_chrX_48896632_ENST00000315869_PRCC_chr1_156752074_ENST00000271526_length(transcript)=2157nt_BP=794nt
GGGAGGAGGGGGAAGAAGACGAGGGGGAGGAGGGCGGTCGTCCGGGGTTAGGTTGAGGGGGGGCGTCGGTCCGTTCTGGGCGGGGGATGA
CTCACAGCCCATCCCATCTCCCAGACGCCGCCCGCCCGCGCAGTGCTAGCTCCATGGCTTAGCGGAGGAGGCGGCAGTGGCGAGCTGGGG
GGAGGGGGGACTCTTATTTTGTTAGGGGGACCGGGCCGAGGCCCGACCGGCCTGGCAGGGCTCGCCCGGGGCCGGGCGTCATGTCTCATG
CGGCCGAACCAGCTCGGGATGGCGTAGAGGCCAGCGCGGAGGGCCCTCGAGCCGTGTTCGTGCTGTTGGAGGAGCGCAGGCCGGCCGACT
CGGCTCAGCTGCTCAGCCTGAACTCTTTGCTTCCGGAATCCGGGATTGTTGCTGACATAGAATTAGAAAACGTCCTTGATCCTGACAGCT
TCTACGAGCTCAAAAGCCAACCCTTACCCCTTCGCTCAAGCCTCCCAATATCACTGCAGGCCACACCAGCCACCCCAGCTACACTCTCTG
CATCGTCTTCTGCAGGGGGCTCCAGGACCCCTGCCATGTCGTCATCTTCTTCATCGAGGGTCTTGCTGCGGCAGCAGCTAATGCGGGCCC
AGGCGCAGGAGCAGGAGAGGCGTGAGCGTCGGGAACAGGCCGCCGCGGCTCCCTTCCCCAGTCCTGCACCTGCCTCTCCTGCCATCTCTG
TGGTTGGCGTCTCTGCTGGGGGCCACACATTGAGCCGTCCACCCCCTGCTCAGGTGCCCAGGGAGGTGCTCAAGTCAGATTCTGAGGAAG
ATGAACCCACAAAGAAGAAAACTATCCTTCAGGGATCCAGTGAGGGGACTGGTTTGTCTGCCTTGCTTCCCCAACCTAAAAACCTGACTG
TGAAAGAGACTAACAGGTTGCTCCTGCCCCATGCCTTCTCCCGCAAACCCTCGGATGGCTCCCCTGATACTAAGCCCTCCAGACTGGCTT
CTAAGACCAAGACTTCCTCTCTTGCCCCTGTTGTGGGCACCACAACCACCACTCCGTCGCCCTCTGCTATCAAGGCTGCTGCCAAGAGTG
CTGCCCTGCAGGTGACAAAGCAGATCACGCAGGAAGAAGACGACAGTGATGAGGAAGTAGCCCCCGAAAACTTTTTCTCCCTCCCTGAAA
AGGCTGAGCCACCTGGAGTTGAGCCATACCCTTACCCCATCCCCACTGTCCCTGAAGAGCTGCCTCCAGGCACGGAACCAGAGCCGGCTT
TCCAGGACGATGCAGCCAATGCCCCCCTTGAATTCAAGATGGCAGCAGGTTCAAGTGGGGCCCCTTGGATGCCTAAGCCTGGGGACGACT
ACAGCTACAATCAGTTTTCCACATATGGCGATGCCAATGCCGCTGGTGCTTATTATCAGGATTATTACAGTGGTGGCTACTATCCTGCAC
AGGACCCGGCCCTGGTCCCCCCCCAGGAAATTGCCCCAGATGCCTCCTTCATCGATGACGAAGCATTTAAGCGGCTGCAGGGCAAGAGGA
ACCGAGGGAGAGAAGAAATCAACTTTGTGGAGATCAAAGGTGATGACCAGCTCAGTGGGGCCCAGCAATGGATGACTAAGTCATTGACAG
AAGAGAAAACCATGAAGTCATTCAGCAAAAAGAAAGGTGAGCAGCCAACAGGCCAGCAGCGGCGGAAACACCAGATCACATATCTTATTC
ATCAGGCCAAGGAGCGGGAGCTGGAACTGAAGAACACCTGGTCAGAGAACAAGCTCAGCCGCCGTCAGACCCAAGCCAAATATGGATTCT
AGGGCTCTGGAACTGATTGCTCCCAGGATCTCCTGCCAGCCCAGCTGGCCTGGCCCCCAGCTTCACCTCTGGGACCCCAGCTGCTCTAAG
CCCAGGATCTCTTTCCCCAAGGACCCAGCCCTCGCCTCTGCGAGAATGAACATATTTGATAGATTTTTCTTAACAAGTTAGAAAATTCAG
CTCCTTTCTGTCCTGGAGCTAGCAAAGACTTGTGTGATGCCTCCGAAGGGGCTCTGAGTTCTGGGGTGGGAGTTTTGCTCTCTGTCAGGT

>90319_90319_5_TFE3-PRCC_TFE3_chrX_48896632_ENST00000315869_PRCC_chr1_156752074_ENST00000271526_length(amino acids)=513AA_BP=57
MSHAAEPARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELENVLDPDSFYELKSQPLPLRSSLPISLQATPATPA
TLSASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKSD
SEEDEPTKKKTILQGSSEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAA
AKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKP
GDDYSYNQFSTYGDANAAGAYYQDYYSGGYYPAQDPALVPPQEIAPDASFIDDEAFKRLQGKRNRGREEINFVEIKGDDQLSGAQQWMTK

--------------------------------------------------------------
>90319_90319_6_TFE3-PRCC_TFE3_chrX_48896632_ENST00000315869_PRCC_chr1_156752074_ENST00000353233_length(transcript)=2056nt_BP=794nt
GGGAGGAGGGGGAAGAAGACGAGGGGGAGGAGGGCGGTCGTCCGGGGTTAGGTTGAGGGGGGGCGTCGGTCCGTTCTGGGCGGGGGATGA
CTCACAGCCCATCCCATCTCCCAGACGCCGCCCGCCCGCGCAGTGCTAGCTCCATGGCTTAGCGGAGGAGGCGGCAGTGGCGAGCTGGGG
GGAGGGGGGACTCTTATTTTGTTAGGGGGACCGGGCCGAGGCCCGACCGGCCTGGCAGGGCTCGCCCGGGGCCGGGCGTCATGTCTCATG
CGGCCGAACCAGCTCGGGATGGCGTAGAGGCCAGCGCGGAGGGCCCTCGAGCCGTGTTCGTGCTGTTGGAGGAGCGCAGGCCGGCCGACT
CGGCTCAGCTGCTCAGCCTGAACTCTTTGCTTCCGGAATCCGGGATTGTTGCTGACATAGAATTAGAAAACGTCCTTGATCCTGACAGCT
TCTACGAGCTCAAAAGCCAACCCTTACCCCTTCGCTCAAGCCTCCCAATATCACTGCAGGCCACACCAGCCACCCCAGCTACACTCTCTG
CATCGTCTTCTGCAGGGGGCTCCAGGACCCCTGCCATGTCGTCATCTTCTTCATCGAGGGTCTTGCTGCGGCAGCAGCTAATGCGGGCCC
AGGCGCAGGAGCAGGAGAGGCGTGAGCGTCGGGAACAGGCCGCCGCGGCTCCCTTCCCCAGTCCTGCACCTGCCTCTCCTGCCATCTCTG
TGGTTGGCGTCTCTGCTGGGGGCCACACATTGAGCCGTCCACCCCCTGCTCAGGTGCCCAGGGAGGTGCTCAAGTCAGATTCTGAGGAAG
ATGAACCCACAAAGAAGAAAACTATCCTTCAGGGATCCAGTGAGGGGACTGGTTTGTCTGCCTTGCTTCCCCAACCTAAAAACCTGACTG
TGAAAGAGACTAACAGGTTGCTCCTGCCCCATGCCTTCTCCCGCAAACCCTCGGATGGCTCCCCTGATACTAAGCCCTCCAGACTGGCTT
CTAAGACCAAGACTTCCTCTCTTGCCCCTGTTGTGGGCACCACAACCACCACTCCGTCGCCCTCTGCTATCAAGGCTGCTGCCAAGAGTG
CTGCCCTGCAGGTGACAAAGCAGATCACGCAGGAAGAAGACGACAGTGATGAGGAAGTAGCCCCCGAAAACTTTTTCTCCCTCCCTGAAA
AGGCTGAGCCACCTGGAGTTGAGCCATACCCTTACCCCATCCCCACTGTCCCTGAAGAGCTGCCTCCAGGCACGGAACCAGAGCCGGCTT
TCCAGGACGATGCAGCCAATGCCCCCCTTGAATTCAAGATGGCAGCAGGTTCAAGTGGGGCCCCTTGGATGCCTAAGCCTGGGGACGACT
ACAGCTACAATCAGTTTTCCACATATGGCGATGCCAATGCCGCTGGTGCTTATTATCAGTTTAAGCGGCTGCAGGGCAAGAGGAACCGAG
GGAGAGAAGAAATCAACTTTGTGGAGATCAAAGGTGATGACCAGCTCAGTGGGGCCCAGCAATGGATGACTAAGTCATTGACAGAAGAGA
AAACCATGAAGTCATTCAGCAAAAAGAAAGGTGAGCAGCCAACAGGCCAGCAGCGGCGGAAACACCAGATCACATATCTTATTCATCAGG
CCAAGGAGCGGGAGCTGGAACTGAAGAACACCTGGTCAGAGAACAAGCTCAGCCGCCGTCAGACCCAAGCCAAATATGGATTCTAGGGCT
CTGGAACTGATTGCTCCCAGGATCTCCTGCCAGCCCAGCTGGCCTGGCCCCCAGCTTCACCTCTGGGACCCCAGCTGCTCTAAGCCCAGG
ATCTCTTTCCCCAAGGACCCAGCCCTCGCCTCTGCGAGAATGAACATATTTGATAGATTTTTCTTAACAAGTTAGAAAATTCAGCTCCTT
TCTGTCCTGGAGCTAGCAAAGACTTGTGTGATGCCTCCGAAGGGGCTCTGAGTTCTGGGGTGGGAGTTTTGCTCTCTGTCAGGTGTGATA

>90319_90319_6_TFE3-PRCC_TFE3_chrX_48896632_ENST00000315869_PRCC_chr1_156752074_ENST00000353233_length(amino acids)=481AA_BP=57
MSHAAEPARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELENVLDPDSFYELKSQPLPLRSSLPISLQATPATPA
TLSASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKSD
SEEDEPTKKKTILQGSSEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAA
AKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKP
GDDYSYNQFSTYGDANAAGAYYQFKRLQGKRNRGREEINFVEIKGDDQLSGAQQWMTKSLTEEKTMKSFSKKKGEQPTGQQRRKHQITYL

--------------------------------------------------------------
>90319_90319_7_TFE3-PRCC_TFE3_chrX_48896632_ENST00000315869_PRCC_chr1_156756400_ENST00000271526_length(transcript)=2109nt_BP=794nt
GGGAGGAGGGGGAAGAAGACGAGGGGGAGGAGGGCGGTCGTCCGGGGTTAGGTTGAGGGGGGGCGTCGGTCCGTTCTGGGCGGGGGATGA
CTCACAGCCCATCCCATCTCCCAGACGCCGCCCGCCCGCGCAGTGCTAGCTCCATGGCTTAGCGGAGGAGGCGGCAGTGGCGAGCTGGGG
GGAGGGGGGACTCTTATTTTGTTAGGGGGACCGGGCCGAGGCCCGACCGGCCTGGCAGGGCTCGCCCGGGGCCGGGCGTCATGTCTCATG
CGGCCGAACCAGCTCGGGATGGCGTAGAGGCCAGCGCGGAGGGCCCTCGAGCCGTGTTCGTGCTGTTGGAGGAGCGCAGGCCGGCCGACT
CGGCTCAGCTGCTCAGCCTGAACTCTTTGCTTCCGGAATCCGGGATTGTTGCTGACATAGAATTAGAAAACGTCCTTGATCCTGACAGCT
TCTACGAGCTCAAAAGCCAACCCTTACCCCTTCGCTCAAGCCTCCCAATATCACTGCAGGCCACACCAGCCACCCCAGCTACACTCTCTG
CATCGTCTTCTGCAGGGGGCTCCAGGACCCCTGCCATGTCGTCATCTTCTTCATCGAGGGTCTTGCTGCGGCAGCAGCTAATGCGGGCCC
AGGCGCAGGAGCAGGAGAGGCGTGAGCGTCGGGAACAGGCCGCCGCGGCTCCCTTCCCCAGTCCTGCACCTGCCTCTCCTGCCATCTCTG
TGGTTGGCGTCTCTGCTGGGGGCCACACATTGAGCCGTCCACCCCCTGCTCAGGTGCCCAGGGAGGTGCTCAAGGGATCCAGTGAGGGGA
CTGGTTTGTCTGCCTTGCTTCCCCAACCTAAAAACCTGACTGTGAAAGAGACTAACAGGTTGCTCCTGCCCCATGCCTTCTCCCGCAAAC
CCTCGGATGGCTCCCCTGATACTAAGCCCTCCAGACTGGCTTCTAAGACCAAGACTTCCTCTCTTGCCCCTGTTGTGGGCACCACAACCA
CCACTCCGTCGCCCTCTGCTATCAAGGCTGCTGCCAAGAGTGCTGCCCTGCAGGTGACAAAGCAGATCACGCAGGAAGAAGACGACAGTG
ATGAGGAAGTAGCCCCCGAAAACTTTTTCTCCCTCCCTGAAAAGGCTGAGCCACCTGGAGTTGAGCCATACCCTTACCCCATCCCCACTG
TCCCTGAAGAGCTGCCTCCAGGCACGGAACCAGAGCCGGCTTTCCAGGACGATGCAGCCAATGCCCCCCTTGAATTCAAGATGGCAGCAG
GTTCAAGTGGGGCCCCTTGGATGCCTAAGCCTGGGGACGACTACAGCTACAATCAGTTTTCCACATATGGCGATGCCAATGCCGCTGGTG
CTTATTATCAGGATTATTACAGTGGTGGCTACTATCCTGCACAGGACCCGGCCCTGGTCCCCCCCCAGGAAATTGCCCCAGATGCCTCCT
TCATCGATGACGAAGCATTTAAGCGGCTGCAGGGCAAGAGGAACCGAGGGAGAGAAGAAATCAACTTTGTGGAGATCAAAGGTGATGACC
AGCTCAGTGGGGCCCAGCAATGGATGACTAAGTCATTGACAGAAGAGAAAACCATGAAGTCATTCAGCAAAAAGAAAGGTGAGCAGCCAA
CAGGCCAGCAGCGGCGGAAACACCAGATCACATATCTTATTCATCAGGCCAAGGAGCGGGAGCTGGAACTGAAGAACACCTGGTCAGAGA
ACAAGCTCAGCCGCCGTCAGACCCAAGCCAAATATGGATTCTAGGGCTCTGGAACTGATTGCTCCCAGGATCTCCTGCCAGCCCAGCTGG
CCTGGCCCCCAGCTTCACCTCTGGGACCCCAGCTGCTCTAAGCCCAGGATCTCTTTCCCCAAGGACCCAGCCCTCGCCTCTGCGAGAATG
AACATATTTGATAGATTTTTCTTAACAAGTTAGAAAATTCAGCTCCTTTCTGTCCTGGAGCTAGCAAAGACTTGTGTGATGCCTCCGAAG
GGGCTCTGAGTTCTGGGGTGGGAGTTTTGCTCTCTGTCAGGTGTGATAAAATGTTGAACCCTCCCCACCACCACTTTTTTTTTTTTAAAC

>90319_90319_7_TFE3-PRCC_TFE3_chrX_48896632_ENST00000315869_PRCC_chr1_156756400_ENST00000271526_length(amino acids)=497AA_BP=57
MSHAAEPARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELENVLDPDSFYELKSQPLPLRSSLPISLQATPATPA
TLSASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKGS
SEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAAAKSAALQVTKQITQEE
DDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDAN
AAGAYYQDYYSGGYYPAQDPALVPPQEIAPDASFIDDEAFKRLQGKRNRGREEINFVEIKGDDQLSGAQQWMTKSLTEEKTMKSFSKKKG

--------------------------------------------------------------
>90319_90319_8_TFE3-PRCC_TFE3_chrX_48896632_ENST00000315869_PRCC_chr1_156756400_ENST00000353233_length(transcript)=2008nt_BP=794nt
GGGAGGAGGGGGAAGAAGACGAGGGGGAGGAGGGCGGTCGTCCGGGGTTAGGTTGAGGGGGGGCGTCGGTCCGTTCTGGGCGGGGGATGA
CTCACAGCCCATCCCATCTCCCAGACGCCGCCCGCCCGCGCAGTGCTAGCTCCATGGCTTAGCGGAGGAGGCGGCAGTGGCGAGCTGGGG
GGAGGGGGGACTCTTATTTTGTTAGGGGGACCGGGCCGAGGCCCGACCGGCCTGGCAGGGCTCGCCCGGGGCCGGGCGTCATGTCTCATG
CGGCCGAACCAGCTCGGGATGGCGTAGAGGCCAGCGCGGAGGGCCCTCGAGCCGTGTTCGTGCTGTTGGAGGAGCGCAGGCCGGCCGACT
CGGCTCAGCTGCTCAGCCTGAACTCTTTGCTTCCGGAATCCGGGATTGTTGCTGACATAGAATTAGAAAACGTCCTTGATCCTGACAGCT
TCTACGAGCTCAAAAGCCAACCCTTACCCCTTCGCTCAAGCCTCCCAATATCACTGCAGGCCACACCAGCCACCCCAGCTACACTCTCTG
CATCGTCTTCTGCAGGGGGCTCCAGGACCCCTGCCATGTCGTCATCTTCTTCATCGAGGGTCTTGCTGCGGCAGCAGCTAATGCGGGCCC
AGGCGCAGGAGCAGGAGAGGCGTGAGCGTCGGGAACAGGCCGCCGCGGCTCCCTTCCCCAGTCCTGCACCTGCCTCTCCTGCCATCTCTG
TGGTTGGCGTCTCTGCTGGGGGCCACACATTGAGCCGTCCACCCCCTGCTCAGGTGCCCAGGGAGGTGCTCAAGGGATCCAGTGAGGGGA
CTGGTTTGTCTGCCTTGCTTCCCCAACCTAAAAACCTGACTGTGAAAGAGACTAACAGGTTGCTCCTGCCCCATGCCTTCTCCCGCAAAC
CCTCGGATGGCTCCCCTGATACTAAGCCCTCCAGACTGGCTTCTAAGACCAAGACTTCCTCTCTTGCCCCTGTTGTGGGCACCACAACCA
CCACTCCGTCGCCCTCTGCTATCAAGGCTGCTGCCAAGAGTGCTGCCCTGCAGGTGACAAAGCAGATCACGCAGGAAGAAGACGACAGTG
ATGAGGAAGTAGCCCCCGAAAACTTTTTCTCCCTCCCTGAAAAGGCTGAGCCACCTGGAGTTGAGCCATACCCTTACCCCATCCCCACTG
TCCCTGAAGAGCTGCCTCCAGGCACGGAACCAGAGCCGGCTTTCCAGGACGATGCAGCCAATGCCCCCCTTGAATTCAAGATGGCAGCAG
GTTCAAGTGGGGCCCCTTGGATGCCTAAGCCTGGGGACGACTACAGCTACAATCAGTTTTCCACATATGGCGATGCCAATGCCGCTGGTG
CTTATTATCAGTTTAAGCGGCTGCAGGGCAAGAGGAACCGAGGGAGAGAAGAAATCAACTTTGTGGAGATCAAAGGTGATGACCAGCTCA
GTGGGGCCCAGCAATGGATGACTAAGTCATTGACAGAAGAGAAAACCATGAAGTCATTCAGCAAAAAGAAAGGTGAGCAGCCAACAGGCC
AGCAGCGGCGGAAACACCAGATCACATATCTTATTCATCAGGCCAAGGAGCGGGAGCTGGAACTGAAGAACACCTGGTCAGAGAACAAGC
TCAGCCGCCGTCAGACCCAAGCCAAATATGGATTCTAGGGCTCTGGAACTGATTGCTCCCAGGATCTCCTGCCAGCCCAGCTGGCCTGGC
CCCCAGCTTCACCTCTGGGACCCCAGCTGCTCTAAGCCCAGGATCTCTTTCCCCAAGGACCCAGCCCTCGCCTCTGCGAGAATGAACATA
TTTGATAGATTTTTCTTAACAAGTTAGAAAATTCAGCTCCTTTCTGTCCTGGAGCTAGCAAAGACTTGTGTGATGCCTCCGAAGGGGCTC
TGAGTTCTGGGGTGGGAGTTTTGCTCTCTGTCAGGTGTGATAAAATGTTGAACCCTCCCCACCACCACTTTTTTTTTTTTAAACCAGGGA

>90319_90319_8_TFE3-PRCC_TFE3_chrX_48896632_ENST00000315869_PRCC_chr1_156756400_ENST00000353233_length(amino acids)=465AA_BP=57
MSHAAEPARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELENVLDPDSFYELKSQPLPLRSSLPISLQATPATPA
TLSASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKGS
SEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAAAKSAALQVTKQITQEE
DDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDAN
AAGAYYQFKRLQGKRNRGREEINFVEIKGDDQLSGAQQWMTKSLTEEKTMKSFSKKKGEQPTGQQRRKHQITYLIHQAKERELELKNTWS

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Fusion Gene PPI Analysis for TFE3-PRCC


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TFE3-PRCC


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TFE3-PRCC


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource