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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:THADA-IGF2BP3 (FusionGDB2 ID:90565)

Fusion Gene Summary for THADA-IGF2BP3

check button Fusion gene summary
Fusion gene informationFusion gene name: THADA-IGF2BP3
Fusion gene ID: 90565
HgeneTgene
Gene symbol

THADA

IGF2BP3

Gene ID

63892

10643

Gene nameTHADA armadillo repeat containinginsulin like growth factor 2 mRNA binding protein 3
SynonymsARMC13|GITACT98|IMP-3|IMP3|KOC|KOC1|VICKZ3
Cytomap

2p21

7p15.3

Type of geneprotein-codingprotein-coding
Descriptionthyroid adenoma-associated proteindeath receptor-interacting proteingene inducing thyroid adenomas proteininsulin-like growth factor 2 mRNA-binding protein 3IGF-II mRNA-binding protein 3IGF2 mRNA-binding protein 3KH domain containing protein overexpressed in cancerVICKZ family member 3cancer/testis antigen 98
Modification date2020031320200313
UniProtAcc.

O00425

Ensembl transtripts involved in fusion geneENST00000405006, ENST00000405975, 
ENST00000415080, ENST00000485353, 
ENST00000330266, ENST00000402360, 
ENST00000403856, ENST00000404790, 
ENST00000491719, ENST00000258729, 
Fusion gene scores* DoF score16 X 16 X 12=30727 X 6 X 5=210
# samples 187
** MAII scorelog2(18/3072*10)=-4.09310940439148
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/210*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: THADA [Title/Abstract] AND IGF2BP3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTHADA(43625110)-IGF2BP3(23458443), # samples:2
Anticipated loss of major functional domain due to fusion event.THADA-IGF2BP3 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across THADA (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across IGF2BP3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4THCATCGA-BJ-A28V-01ATHADAchr2

43625110

-IGF2BP3chr7

23458443

-
ChimerDB4THCATCGA-DJ-A1QL-01ATHADAchr2

43547585

-IGF2BP3chr7

23458443

-


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Fusion Gene ORF analysis for THADA-IGF2BP3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000405006ENST00000491719THADAchr2

43625110

-IGF2BP3chr7

23458443

-
5CDS-5UTRENST00000405006ENST00000491719THADAchr2

43547585

-IGF2BP3chr7

23458443

-
5CDS-5UTRENST00000405975ENST00000491719THADAchr2

43625110

-IGF2BP3chr7

23458443

-
5CDS-5UTRENST00000405975ENST00000491719THADAchr2

43547585

-IGF2BP3chr7

23458443

-
5CDS-5UTRENST00000415080ENST00000491719THADAchr2

43625110

-IGF2BP3chr7

23458443

-
5CDS-5UTRENST00000415080ENST00000491719THADAchr2

43547585

-IGF2BP3chr7

23458443

-
5UTR-3CDSENST00000485353ENST00000258729THADAchr2

43625110

-IGF2BP3chr7

23458443

-
5UTR-5UTRENST00000485353ENST00000491719THADAchr2

43625110

-IGF2BP3chr7

23458443

-
Frame-shiftENST00000405006ENST00000258729THADAchr2

43625110

-IGF2BP3chr7

23458443

-
Frame-shiftENST00000405975ENST00000258729THADAchr2

43547585

-IGF2BP3chr7

23458443

-
Frame-shiftENST00000415080ENST00000258729THADAchr2

43547585

-IGF2BP3chr7

23458443

-
In-frameENST00000405006ENST00000258729THADAchr2

43547585

-IGF2BP3chr7

23458443

-
In-frameENST00000405975ENST00000258729THADAchr2

43625110

-IGF2BP3chr7

23458443

-
In-frameENST00000415080ENST00000258729THADAchr2

43625110

-IGF2BP3chr7

23458443

-
intron-3CDSENST00000330266ENST00000258729THADAchr2

43625110

-IGF2BP3chr7

23458443

-
intron-3CDSENST00000330266ENST00000258729THADAchr2

43547585

-IGF2BP3chr7

23458443

-
intron-3CDSENST00000402360ENST00000258729THADAchr2

43625110

-IGF2BP3chr7

23458443

-
intron-3CDSENST00000402360ENST00000258729THADAchr2

43547585

-IGF2BP3chr7

23458443

-
intron-3CDSENST00000403856ENST00000258729THADAchr2

43625110

-IGF2BP3chr7

23458443

-
intron-3CDSENST00000403856ENST00000258729THADAchr2

43547585

-IGF2BP3chr7

23458443

-
intron-3CDSENST00000404790ENST00000258729THADAchr2

43625110

-IGF2BP3chr7

23458443

-
intron-3CDSENST00000404790ENST00000258729THADAchr2

43547585

-IGF2BP3chr7

23458443

-
intron-3CDSENST00000485353ENST00000258729THADAchr2

43547585

-IGF2BP3chr7

23458443

-
intron-5UTRENST00000330266ENST00000491719THADAchr2

43625110

-IGF2BP3chr7

23458443

-
intron-5UTRENST00000330266ENST00000491719THADAchr2

43547585

-IGF2BP3chr7

23458443

-
intron-5UTRENST00000402360ENST00000491719THADAchr2

43625110

-IGF2BP3chr7

23458443

-
intron-5UTRENST00000402360ENST00000491719THADAchr2

43547585

-IGF2BP3chr7

23458443

-
intron-5UTRENST00000403856ENST00000491719THADAchr2

43625110

-IGF2BP3chr7

23458443

-
intron-5UTRENST00000403856ENST00000491719THADAchr2

43547585

-IGF2BP3chr7

23458443

-
intron-5UTRENST00000404790ENST00000491719THADAchr2

43625110

-IGF2BP3chr7

23458443

-
intron-5UTRENST00000404790ENST00000491719THADAchr2

43547585

-IGF2BP3chr7

23458443

-
intron-5UTRENST00000485353ENST00000491719THADAchr2

43547585

-IGF2BP3chr7

23458443

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000405975THADAchr243625110-ENST00000258729IGF2BP3chr723458443-8024436714044261428
ENST00000415080THADAchr243625110-ENST00000258729IGF2BP3chr723458443-7937428014043391399
ENST00000405006THADAchr243547585-ENST00000258729IGF2BP3chr723458443-8447479035248571501

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000405975ENST00000258729THADAchr243625110-IGF2BP3chr723458443-0.0001639860.99983597
ENST00000415080ENST00000258729THADAchr243625110-IGF2BP3chr723458443-0.000236840.9997632
ENST00000405006ENST00000258729THADAchr243547585-IGF2BP3chr723458443-0.0005858370.9994142

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Fusion Genomic Features for THADA-IGF2BP3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for THADA-IGF2BP3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:43625110/chr7:23458443)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.IGF2BP3

O00425

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. {ECO:0000269|PubMed:16541107, ECO:0000269|PubMed:23640942}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTHADAchr2:43547585chr7:23458443ENST00000405006-3138886_91814791954.0Coiled coilOntology_term=ECO:0000255
HgeneTHADAchr2:43547585chr7:23458443ENST00000405975-3138886_91814791954.0Coiled coilOntology_term=ECO:0000255
HgeneTHADAchr2:43625110chr7:23458443ENST00000405006-2938886_91814091954.0Coiled coilOntology_term=ECO:0000255
HgeneTHADAchr2:43625110chr7:23458443ENST00000405975-2938886_91814091954.0Coiled coilOntology_term=ECO:0000255
HgeneTHADAchr2:43547585chr7:23458443ENST00000405006-31381322_132714791954.0Compositional biasNote=Poly-Leu
HgeneTHADAchr2:43547585chr7:23458443ENST00000405006-31384_714791954.0Compositional biasNote=Poly-Lys
HgeneTHADAchr2:43547585chr7:23458443ENST00000405975-31381322_132714791954.0Compositional biasNote=Poly-Leu
HgeneTHADAchr2:43547585chr7:23458443ENST00000405975-31384_714791954.0Compositional biasNote=Poly-Lys
HgeneTHADAchr2:43625110chr7:23458443ENST00000405006-29381322_132714091954.0Compositional biasNote=Poly-Leu
HgeneTHADAchr2:43625110chr7:23458443ENST00000405006-29384_714091954.0Compositional biasNote=Poly-Lys
HgeneTHADAchr2:43625110chr7:23458443ENST00000405975-29381322_132714091954.0Compositional biasNote=Poly-Leu
HgeneTHADAchr2:43625110chr7:23458443ENST00000405975-29384_714091954.0Compositional biasNote=Poly-Lys
TgeneIGF2BP3chr2:43547585chr7:23458443ENST00000258729115195_26078580.0DomainKH 1
TgeneIGF2BP3chr2:43547585chr7:23458443ENST00000258729115276_34378580.0DomainKH 2
TgeneIGF2BP3chr2:43547585chr7:23458443ENST00000258729115405_47078580.0DomainKH 3
TgeneIGF2BP3chr2:43547585chr7:23458443ENST00000258729115487_55378580.0DomainKH 4
TgeneIGF2BP3chr2:43547585chr7:23458443ENST0000025872911581_15678580.0DomainRRM 2
TgeneIGF2BP3chr2:43625110chr7:23458443ENST00000258729115195_26078580.0DomainKH 1
TgeneIGF2BP3chr2:43625110chr7:23458443ENST00000258729115276_34378580.0DomainKH 2
TgeneIGF2BP3chr2:43625110chr7:23458443ENST00000258729115405_47078580.0DomainKH 3
TgeneIGF2BP3chr2:43625110chr7:23458443ENST00000258729115487_55378580.0DomainKH 4
TgeneIGF2BP3chr2:43625110chr7:23458443ENST0000025872911581_15678580.0DomainRRM 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTHADAchr2:43547585chr7:23458443ENST00000402360-117886_9180938.0Coiled coilOntology_term=ECO:0000255
HgeneTHADAchr2:43625110chr7:23458443ENST00000402360-117886_9180938.0Coiled coilOntology_term=ECO:0000255
HgeneTHADAchr2:43547585chr7:23458443ENST00000402360-1171322_13270938.0Compositional biasNote=Poly-Leu
HgeneTHADAchr2:43547585chr7:23458443ENST00000402360-1171529_15320938.0Compositional biasNote=Poly-Ala
HgeneTHADAchr2:43547585chr7:23458443ENST00000402360-1174_70938.0Compositional biasNote=Poly-Lys
HgeneTHADAchr2:43547585chr7:23458443ENST00000405006-31381529_153214791954.0Compositional biasNote=Poly-Ala
HgeneTHADAchr2:43547585chr7:23458443ENST00000405975-31381529_153214791954.0Compositional biasNote=Poly-Ala
HgeneTHADAchr2:43625110chr7:23458443ENST00000402360-1171322_13270938.0Compositional biasNote=Poly-Leu
HgeneTHADAchr2:43625110chr7:23458443ENST00000402360-1171529_15320938.0Compositional biasNote=Poly-Ala
HgeneTHADAchr2:43625110chr7:23458443ENST00000402360-1174_70938.0Compositional biasNote=Poly-Lys
HgeneTHADAchr2:43625110chr7:23458443ENST00000405006-29381529_153214091954.0Compositional biasNote=Poly-Ala
HgeneTHADAchr2:43625110chr7:23458443ENST00000405975-29381529_153214091954.0Compositional biasNote=Poly-Ala
TgeneIGF2BP3chr2:43547585chr7:23458443ENST000002587291152_7578580.0DomainRRM 1
TgeneIGF2BP3chr2:43625110chr7:23458443ENST000002587291152_7578580.0DomainRRM 1


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Fusion Gene Sequence for THADA-IGF2BP3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>90565_90565_1_THADA-IGF2BP3_THADA_chr2_43547585_ENST00000405006_IGF2BP3_chr7_23458443_ENST00000258729_length(transcript)=8447nt_BP=4790nt
GGACCAGGCGCCTGCGACTCTTCTCAGACGCCGACGTGCACGAGGTTTGGCTCCCAGGTGTCCTGCCTGCCAGACCCGCGGTAGCTCGGC
TCGGCCAGTTTTGCTAGGGCTGCCTGGCGAGCCACACCAATTCCCATCCTTTGGTATCGCCAGGATTCGGCGGCTGTGAAACTGATTTCC
GGTCGCTAAGGTCTCCATGGAGACAGCACTTTAACCACTTTCTCCCACTGTCATTCCTCGACTCCACGTGGTTCAGAAATCGCCCAGAGA
ATGTTTGTGGGAGTCAGCCAGGAAGGTGTAGAGTGAAGCAGCGTTCTAAAGGGAAGCATGACTACTATTAATTCTATTTAAAATGGGTGT
AAAGAAGAAGAAAGAAATGCAAGTTGCTGCGCTGACCATTTGCCATCAGGACCTTGAAACTTTGAAATCTTTTGCTGATGTGGAAGGGAA
AAATCTAGCTTCTTTGCTGTTACATTGTGTGCAACTCACGGATGGAGTGTCACAAATCCATTATATTAAACAGATTGTGCCTCTGCTGGA
GAAAGCAGATAAAAATGGCATGTGTGATCCCACTATTCAAAGTTGTTTGGATATCTTAGCAGGCATTTATCTTTCTTTGAGTCTAAAGAA
TCCCTTGAAGAAAGTATTGGCAAGCTCACTAAATAGCCTGCCTGATTTTTTTCTACCTGAGGCTATGCACCGTTTTACTTCTCGTCTTCA
GGAAGAATTGAATACTACTGACTTATACTCTTACAGGAAAGTTACTGACAATATTTCTTCCTGTATGGAGAACTTTAACTTGGGTAGAGC
AAGTGTTAATAATCTGCTTAAAAATGTGCTTCATTTTCTGCAGAAGAGTTTAATTGAAATCCTGGAAGAAAATAGAAAATGTGCTGGAAA
TCATATTATTCAAACACAGTTGATGAATGACTTACTGGTAGGCATTAGAGTTTCAATGATGTTAGTACAGAAAGTACAAGATTTCCAGGG
AAATCTTTGGAAGACTTCCGATTCTCCCATATGGCAAAATATGTGTGGATTGCTGAGTATTTTTACCAAGGTTTTAAGCGATGATGATCT
GTTACAGACTGTACAGAGCACATCTGGATTAGCTATTATTCTTTTTATTAAGACTATGTTTCACCCGTCTGAAAAGATTCCTCATTTGAT
TAGCAGTGTGCTGCTTCGTTCAGTGGACTGCACCAGTGTCCCCGAGTGGTTTATGAGCAGCTGCAGGAGCCTCTGTTGTGGTGACATCTC
TCAGTCAGCTGTCTTATTCCTCTGTCAGGGGACACTTGCCATGTTGGACTGGCAGAACGGAAGCATGGGTCGGAGTGGGGAGGCCCTGCT
CTTGGATACTGCACATGTTTTGTTCACCTTGAGTTCACAGATTAAAGAGCCAACGCTGGAAATGTTTCTGTCTAGAATCTTAGCATCCTG
GACTAATTCAGCCATACAAGTCCTTGAATCAAGTTCCCCGAGCCTAACGGACAGCCTGAATGGGAATTCAAGTATAGTTGGGAGACTTTT
GGAATATGTCTATACCCATTGGGAACATCCATTGGATGCTCTGAGACACCAAACCAAAATCATGTTCAAAAACCTTCTCCAAATGCACCG
GCTCACTGTGGAAGGTGCAGATTTCGTCCCTGATCCTTTCTTTGTGGAATTGACTGAGAGTCTTTTACGATTGGAATGGCATATTAAAGG
AAAGTACACGTGCCTTGGTTGTTTGGTAGAGTGCATAGGAGTTGAACATATTTTGGCTATAGATAAAACTATTCCATCTCAAATCTTAGA
GGTGATGGGAGACCAGTCATTGGTACCTTATGCAAGTGACCTCTTGGAAACCATGTTTAGAAATCATAAGAGTCATTTGAAATCCCAGAC
TGCTGAGAGTTCTTGGATTGACCAGTGGCATGAGACTTGGGTTTCTCCTCTCCTTTTTATATTGTGTGAAGGAAACTTGGATCAAAAATC
TTACGTGATTGATTATTACTTGCCAAAATTATTAAGTTACAGCCCTGAAAGCTTACAGTACATGGTAAAGATTCTTCAGACTTCTATTGA
TGCTAAAACTGGACAAGAGCAATCTTTCCCATCCTTAGGGTCTTGTAATAGCAGGGGGGCTCTGGGAGCTTTGATGGCATGTCTGCGAAT
AGCTAGAGCTCATGGACATCTTCAGTCTGCAACTGATACCTGGGAGAACCTCGTGTCTGATGCAAGAATAAAGCAAGGCTTAATTCATCA
GCATTGCCAAGTAAGGATAGATACATTAGGCTTGCTTTGTGAAAGTAATCGGAGCACAGAAATTGTTTCCATGGAAGAAATGCAGTGGAT
TCAGTTCTTTATTACATACAATCTTAACAGCCAGTCTCCAGGAGTGCGGCAACAGATCTGTTCTCTTCTTAAAAAGTTGTTTTGTAGGAT
ACAGGAAAGTTCTCAGGTACTTTATAAATTGGAGCAGAGTAAATCCAAACGTGAACCAGAGAATGAGTTAACCAAACAGCACCCTTCTGT
TTCTTTACAGCAGTATAAGAATTTCATGTCATCCATTTGTAACAGTCTTTTTGAAGCATTGTTTCCTGGATCTTCCTACTCGACTAGATT
TTCAGCTTTAACCATTTTAGGTTCAATAGCTGAAGTTTTTCATGTCCCAGAAGGCAGAATTTATACAGTATATCAGCTGAGTCATGATAT
TGATGTTGGTCGTTTCCAAACACTAATGGAATGTTTTACCAGCACTTTTGAAGACGTGAAAATTTTAGCATTTGATCTTCTGATGAAGTT
ATCAAAAACAGCTGTACATTTTCAGGATTCGGGGAAACTGCAAGGCTTATTTCAGGCAGCATTGGAGCTCAGCACAAGCACCAAACCATA
CGACTGTGTGACAGCTTCCTACCTGCTGAACTTCTTAATCTGGCAGGATGCTCTACCGTCATCCTTGTCTGCCTACTTAACTCAGCAAGT
TGCATGTGATAATGGAGATAGGCCTGCTGCTGTGGTGGAAAGGAACACATTAATGGTTATCAAATGCTTGATGGAAAATCTTGAGGAAGA
AGTATCTCAGGCTGAAAATTCTCTGCTTCAGGCAGCAGCAGCATTTCCAATGTATGGGCGAGTCCACTGTATAACAGGAGCTTTGCAGAA
GTTATCTCTAAACAGCCTGCAGTTGGTGAGCGAGTGGAGACCTGTGGTAGAGAAGCTCCTTTTGATGTCCTACAGGCTTTCCACTGTGGT
GTCTCCAGTCATTCAGAGCTCATCCCCTGAAGGCCTCATCCCAATGGACACTGATTCAGAGTCAGCAAGCCGCTTACAGATGATTCTGAA
TGAGATTCAGCCTCGAGATACTAATGATTATTTTAACCAAGCCAAAATATTGAAAGAACATGATAGCTTTGATATGAAGGACTTGAATGC
TAGTGTGGTGAATATTGATACTTCTACAGAAATCAAAGGTAAAGAAGTAAAAACATGTGATGTAACTGCGCAGATGGTGCTGGTATGTTG
TTGGAGAAGTATGAAGGAAGTTGCTTTACTTTTAGGCATGTTGTGCCAGCTTCTGCCCATGCAGCCTGTGCCAGAATCTTCTGATGGATT
ATTGACGGTGGAGCAGGTAAAAGAAATAGGAGATTACTTTAAACAACACCTTTTGCAGTCCAGGCACAGAGGAGCATTTGAATTGGCTTA
TACTGGTTTTGTGAAACTCACTGAAGTACTAAACAGGTGCCCAAATGTGAGTCTGCAAAAGCTGCCAGAACAGTGGCTATGGAGTGTTTT
AGAGGAAATTAAATGCAGTGATCCTTCATCTAAACTCTGTGCTACAAGGCGCAGTGCTGGAATTCCTTTCTACATACAGGCACTGTTGGC
ATCTGAACCAAAGAAAGGCAGAATGGATTTGTTGAAAATAACAATGAAAGAGTTAATCTCTTTGGCTGGGCCTACAGATGACATACAGAG
TACAGTCCCCCAGGTTCATGCTTTAAATATCCTTAGAGCATTGTTCAGAGATACGCGCCTGGGAGAAAATATTATTCCTTATGTTGCTGA
TGGAGCTAAGGCTGCAATTCTGGGTTTTACATCACCGGTCTGGGCAGTGCGAAATTCATCCACACTTCTCTTTAGTGCCTTGATCACAAG
AATTTTTGGAGTTAAAAGGGCAAAGGATGAACATTCCAAAACAAATAGAATGACAGGGAGAGAGTTTTTCTCTCGTTTCCCAGAACTCTA
TCCTTTTCTTCTCAAACAGTTGGAAACTGTAGCCAATACAGTAGACAGTGATATGGGAGAACCAAATCGTCATCCAAGCATGTTTCTCTT
ACTTTTGGTGTTGGAGAGACTCTACGCTTCCCCGATGGATGGTACTTCTTCTGCTCTCAGCATGGGACCTTTTGTTCCCTTCATTATGAG
GTGTGGTCACTCACCTGTCTACCACTCCCGTGAAATGGCAGCTCGTGCCTTGGTCCCATTTGTTATGATAGATCACATTCCTAATACCAT
TCGAACTCTGTTGTCCACACTCCCCAGCTGCACTGACCAGTGTTTCCGGCAAAACCACATTCATGGGACACTTCTCCAGGTTTTTCATTT
GTTGCAAGCCTACTCAGACTCCAAACACGGAACGAATTCAGACTTCCAGCACGAGCTGACTGACATCACTGTTTGTACCAAAGCCAAACT
CTGGCTGGCCAAGAGGCAAAATCCATGTTTGGTGACCAGAGCTGTATATATTGATATTCTCTTCCTATTGACTTGCTGCCTCAACAGATC
TGCAAAGGACAACCAGCCAGGATTCGGAAACTTCAGATACGAAATATCCCGCCTCATTTACAGTGGGAGGTGCTGGATAGTTTACTAGTC
CAGTATGGAGTGGTGGAGAGCTGTGAGCAAGTGAACACTGACTCGGAAACTGCAGTTGTAAATGTAACCTATTCCAGTAAGGACCAAGCT
AGACAAGCACTAGACAAACTGAATGGATTTCAGTTAGAGAATTTCACCTTGAAAGTAGCCTATATCCCTGATGAAATGGCCGCCCAGCAA
AACCCCTTGCAGCAGCCCCGAGGTCGCCGGGGGCTTGGGCAGAGGGGCTCCTCAAGGCAGGGGTCTCCAGGATCCGTATCCAAGCAGAAA
CCATGTGATTTGCCTCTGCGCCTGCTGGTTCCCACCCAATTTGTTGGAGCCATCATAGGAAAAGAAGGTGCCACCATTCGGAACATCACC
AAACAGACCCAGTCTAAAATCGATGTCCACCGTAAAGAAAATGCGGGGGCTGCTGAGAAGTCGATTACTATCCTCTCTACTCCTGAAGGC
ACCTCTGCGGCTTGTAAGTCTATTCTGGAGATTATGCATAAGGAAGCTCAAGATATAAAATTCACAGAAGAGATCCCCTTGAAGATTTTA
GCTCATAATAACTTTGTTGGACGTCTTATTGGTAAAGAAGGAAGAAATCTTAAAAAAATTGAGCAAGACACAGACACTAAAATCACGATA
TCTCCATTGCAGGAATTGACGCTGTATAATCCAGAACGCACTATTACAGTTAAAGGCAATGTTGAGACATGTGCCAAAGCTGAGGAGGAG
ATCATGAAGAAAATCAGGGAGTCTTATGAAAATGATATTGCTTCTATGAATCTTCAAGCACATTTAATTCCTGGATTAAATCTGAACGCC
TTGGGTCTGTTCCCACCCACTTCAGGGATGCCACCTCCCACCTCAGGGCCCCCTTCAGCCATGACTCCTCCCTACCCGCAGTTTGAGCAA
TCAGAAACGGAGACTGTTCATCTGTTTATCCCAGCTCTATCAGTCGGTGCCATCATCGGCAAGCAGGGCCAGCACATCAAGCAGCTTTCT
CGCTTTGCTGGAGCTTCAATTAAGATTGCTCCAGCGGAAGCACCAGATGCTAAAGTGAGGATGGTGATTATCACTGGACCACCAGAGGCT
CAGTTCAAGGCTCAGGGAAGAATTTATGGAAAAATTAAAGAAGAAAACTTTGTTAGTCCTAAAGAAGAGGTGAAACTTGAAGCTCATATC
AGAGTGCCATCCTTTGCTGCTGGCAGAGTTATTGGAAAAGGAGGCAAAACGGTGAATGAACTTCAGAATTTGTCAAGTGCAGAAGTTGTT
GTCCCTCGTGACCAGACACCTGATGAGAATGACCAAGTGGTTGTCAAAATAACTGGTCACTTCTATGCTTGCCAGGTTGCCCAGAGAAAA
ATTCAGGAAATTCTGACTCAGGTAAAGCAGCACCAACAACAGAAGGCTCTGCAAAGTGGACCACCTCAGTCAAGACGGAAGTAAAGGCTC
AGGAAACAGCCCACCACAGAGGCAGATGCCAAACCAAAGACAGATTGCTTAACCAACAGATGGGCGCTGACCCCCTATCCAGAATCACAT
GCACAAGTTTTTACCTAGCCAGTTGTTTCTGAGGACCAGGCAACTTTTGAACTCCTGTCTCTGTGAGAATGTATACTTTATGCTCTCTGA
AATGTATGACACCCAGCTTTAAAACAAACAAACAAACAAACAAAAAAAGGGTGGGGGAGGGAGGGAAAGAGAAGAGCTCTGCACTTCCCT
TTGTTGTAGTCTCACAGTATAACAGATATTCTAATTCTTCTTAATATTCCCCCATAATGCCAGAAATTGGCTTAATGATGCTTTCACTAA
ATTCATCAAATAGATTGCTCCTAAATCCAATTGTTAAAATTGGATCAGAATAATTATCACAGGAACTTAAATGTTAAGCCATTAGCATAG
AAAAACTGTTCTCAGTTTTATTTTTACCTAACACTAACATGAGTAACCTAAGGGAAGTGCTGAATGGTGTTGGCAGGGGTATTAAACGTG
CATTTTTACTCAACTACCTCAGGTATTCAGTAATACAATGAAAAGCAAAATTGTTCCTTTTTTTTGAAAATTTTATATACTTTATAATGA
TAGAAGTCCAACCGTTTTTTAAAAAATAAATTTAAAATTTAACAGCAATCAGCTAACAGGCAAATTAAGATTTTTACTTCTGGCTGGTGA
CAGTAAAGCTGGAAAATTAATTTCAGGGTTTTTTGAGGCTTTTGACACAGTTATTAGTTAAATCAAATGTTCAAAAATACGGAGCAGTGC
CTAGTATCTGGAGAGCAGCACTACCATTTATTCTTTCATTTATAGTTGGGAAAGTTTTTGACGGTACTAACAAAGTGGTCGCAGGAGATT
TTGGAACGGCTGGTTTAAATGGCTTCAGGAGACTTCAGTTTTTTGTTTAGCTACATGATTGAATGCATAATAAATGCTTTGTGCTTCTGA
CTATCAATACCTAAAGAAAGTGCATCAGTGAAGAGATGCAAGACTTTCAACTGACTGGCAAAAAGCAAGCTTTAGCTTGTCTTATAGGAT
GCTTAGTTTGCCACTACACTTCAGACCAATGGGACAGTCATAGATGGTGTGACAGTGTTTAAACGCAACAAAAGGCTACATTTCCATGGG
GCCAGCACTGTCATGAGCCTCACTAAGCTATTTTGAAGATTTTTAAGCACTGATAAATTAAAAAAAAAAAATTAGACTCCACCTTAAGTA
GTAAAGTATAACAGGATTTCTGTATACTGTGCAATCAGTTCTTTGAAAAAAAAGTCAAAAGATAGAGAATACAAGAAAAGTTTTTGGGAT
ATAATTTGAATGACTGTGAAAACATATGACCTTTGATAACGAACTCATTTGCTCACTCCTTGACAGCAAAGCCCAGTACGTACAATTGTG
TTGGGTGTGGGTGGTCTCCAAGGCCACGCTGCTCTCTGAATTGATTTTTTGAGTTTTGTTTGTAAGATGATCACAGTCATGTTACACTGA
TCTAAAGGACATATATATAACCCTTTAAAAAAAAAATCACTGCCTCATTCTTATTTCAAGATGAATTTCTATACAGACTAGATGTTTTTC
TGAAGATCAATTAGACATTTTGAAAATGATTTAAAGTGTTTTCCTTAATGTTCTCTGAAAACAAGTTTCTTTTGTAGTTTTAACCAAAAA
AGTGCCCTTTTTGTCACTGGATTCTCCTAGCATTCATGATTTTTTTTTCATACAATGAATTAAAATTGCTAAAATCATGGACTGGCTTTC
TGGTTGGATTTCAGGTAAGATGTGTTTAAGGCCAGAGCTTTTCTCAGTATTTGATTTTTTTCCCCAATATTTGATTTTTTAAAAATATAC
ACATAGGTGCTGCATTTATATCTGCTGGTTTAAATTCTGTCATATTTCACTTCTAGCCTTTTAGTATGGCAAATCATATTTTACTTTTAC
TTAAGCATTTGTAATTTGGAGTATCTGGTACTAGCTAAGAAATAATTCTATAATTGAGTTTTGTACTCACCATATATGGATCATTCCTCA

>90565_90565_1_THADA-IGF2BP3_THADA_chr2_43547585_ENST00000405006_IGF2BP3_chr7_23458443_ENST00000258729_length(amino acids)=1501AA_BP=1479
MGVKKKKEMQVAALTICHQDLETLKSFADVEGKNLASLLLHCVQLTDGVSQIHYIKQIVPLLEKADKNGMCDPTIQSCLDILAGIYLSLS
LKNPLKKVLASSLNSLPDFFLPEAMHRFTSRLQEELNTTDLYSYRKVTDNISSCMENFNLGRASVNNLLKNVLHFLQKSLIEILEENRKC
AGNHIIQTQLMNDLLVGIRVSMMLVQKVQDFQGNLWKTSDSPIWQNMCGLLSIFTKVLSDDDLLQTVQSTSGLAIILFIKTMFHPSEKIP
HLISSVLLRSVDCTSVPEWFMSSCRSLCCGDISQSAVLFLCQGTLAMLDWQNGSMGRSGEALLLDTAHVLFTLSSQIKEPTLEMFLSRIL
ASWTNSAIQVLESSSPSLTDSLNGNSSIVGRLLEYVYTHWEHPLDALRHQTKIMFKNLLQMHRLTVEGADFVPDPFFVELTESLLRLEWH
IKGKYTCLGCLVECIGVEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFRNHKSHLKSQTAESSWIDQWHETWVSPLLFILCEGNLD
QKSYVIDYYLPKLLSYSPESLQYMVKILQTSIDAKTGQEQSFPSLGSCNSRGALGALMACLRIARAHGHLQSATDTWENLVSDARIKQGL
IHQHCQVRIDTLGLLCESNRSTEIVSMEEMQWIQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQSKSKREPENELTKQH
PSVSLQQYKNFMSSICNSLFEALFPGSSYSTRFSALTILGSIAEVFHVPEGRIYTVYQLSHDIDVGRFQTLMECFTSTFEDVKILAFDLL
MKLSKTAVHFQDSGKLQGLFQAALELSTSTKPYDCVTASYLLNFLIWQDALPSSLSAYLTQQVACDNGDRPAAVVERNTLMVIKCLMENL
EEEVSQAENSLLQAAAAFPMYGRVHCITGALQKLSLNSLQLVSEWRPVVEKLLLMSYRLSTVVSPVIQSSSPEGLIPMDTDSESASRLQM
ILNEIQPRDTNDYFNQAKILKEHDSFDMKDLNASVVNIDTSTEIKGKEVKTCDVTAQMVLVCCWRSMKEVALLLGMLCQLLPMQPVPESS
DGLLTVEQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEVLNRCPNVSLQKLPEQWLWSVLEEIKCSDPSSKLCATRRSAGIPFYIQA
LLASEPKKGRMDLLKITMKELISLAGPTDDIQSTVPQVHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSAL
ITRIFGVKRAKDEHSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDMGEPNRHPSMFLLLLVLERLYASPMDGTSSALSMGPFVPF
IMRCGHSPVYHSREMAARALVPFVMIDHIPNTIRTLLSTLPSCTDQCFRQNHIHGTLLQVFHLLQAYSDSKHGTNSDFQHELTDITVCTK

--------------------------------------------------------------
>90565_90565_2_THADA-IGF2BP3_THADA_chr2_43625110_ENST00000405975_IGF2BP3_chr7_23458443_ENST00000258729_length(transcript)=8024nt_BP=4367nt
GACCCGGTAGTCGACCGTGGACCGCGCTGCGAGCCTCGGAGACGCCGTAGAAGGAGACCTGCTTCCGGGACTGGACCAGGCGCCTGCGAC
TCTTCTCAGACGCCGACGTGCACGAGTGACTACTATTAATTCTATTTAAAATGGGTGTAAAGAAGAAGAAAGAAATGCAAGTTGCTGCGC
TGACCATTTGCCATCAGGACCTTGAAACTTTGAAATCTTTTGCTGATGTGGAAGGGAAAAATCTAGCTTCTTTGCTGTTACATTGTGTGC
AACTCACGGATGGAGTGTCACAAATCCATTATATTAAACAGATTGTGCCTCTGCTGGAGAAAGCAGATAAAAATGGCATGTGTGATCCCA
CTATTCAAAGTTGTTTGGATATCTTAGCAGGCATTTATCTTTCTTTGAGTCTAAAGAATCCCTTGAAGAAAGTATTGGCAAGCTCACTAA
ATAGCCTGCCTGATTTTTTTCTACCTGAGGCTATGCACCGTTTTACTTCTCGTCTTCAGGAAGAATTGAATACTACTGACTTATACTCTT
ACAGGAAAGTTACTGACAATATTTCTTCCTGTATGGAGAACTTTAACTTGGGTAGAGCAAGTGTTAATAATCTGCTTAAAAATGTGCTTC
ATTTTCTGCAGAAGAGTTTAATTGAAATCCTGGAAGAAAATAGAAAATGTGCTGGAAATCATATTATTCAAACACAGTTGATGAATGACT
TACTGGTAGGCATTAGAGTTTCAATGATGTTAGTACAGAAAGTACAAGATTTCCAGGGAAATCTTTGGAAGACTTCCGATTCTCCCATAT
GGCAAAATATGTGTGGATTGCTGAGTATTTTTACCAAGGTTTTAAGCGATGATGATCTGTTACAGACTGTACAGAGCACATCTGGATTAG
CTATTATTCTTTTTATTAAGACTATGTTTCACCCGTCTGAAAAGATTCCTCATTTGATTAGCAGTGTGCTGCTTCGTTCAGTGGACTGCA
CCAGTGTCCCCGAGTGGTTTATGAGCAGCTGCAGGAGCCTCTGTTGTGGTGACATCTCTCAGTCAGCTGTCTTATTCCTCTGTCAGGGGA
CACTTGCCATGTTGGACTGGCAGAACGGAAGCATGGGTCGGAGTGGGGAGGCCCTGCTCTTGGATACTGCACATGTTTTGTTCACCTTGA
GTTCACAGATTAAAGAGCCAACGCTGGAAATGTTTCTGTCTAGAATCTTAGCATCCTGGACTAATTCAGCCATACAAGTCCTTGAATCAA
GTTCCCCGAGCCTAACGGACAGCCTGAATGGGAATTCAAGTATAGTTGGGAGACTTTTGGAATATGTCTATACCCATTGGGAACATCCAT
TGGATGCTCTGAGACACCAAACCAAAATCATGTTCAAAAACCTTCTCCAAATGCACCGGCTCACTGTGGAAGGTGCAGATTTCGTCCCTG
ATCCTTTCTTTGTGGAATTGACTGAGAGTCTTTTACGATTGGAATGGCATATTAAAGGAAAGTACACGTGCCTTGGTTGTTTGGTAGAGT
GCATAGGAGTTGAACATATTTTGGCTATAGATAAAACTATTCCATCTCAAATCTTAGAGGTGATGGGAGACCAGTCATTGGTACCTTATG
CAAGTGACCTCTTGGAAACCATGTTTAGAAATCATAAGAGTCATTTGAAATCCCAGACTGCTGAGAGTTCTTGGATTGACCAGTGGCATG
AGACTTGGGTTTCTCCTCTCCTTTTTATATTGTGTGAAGGAAACTTGGATCAAAAATCTTACGTGATTGATTATTACTTGCCAAAATTAT
TAAGTTACAGCCCTGAAAGCTTACAGTACATGGTAAAGATTCTTCAGACTTCTATTGATGCTAAAACTGGACAAGAGCAATCTTTCCCAT
CCTTAGGGTCTTGTAATAGCAGGGGGGCTCTGGGAGCTTTGATGGCATGTCTGCGAATAGCTAGAGCTCATGGACATCTTCAGTCTGCAA
CTGATACCTGGGAGAACCTCGTGTCTGATGCAAGAATAAAGCAAGGCTTAATTCATCAGCATTGCCAAGTAAGGATAGATACATTAGGCT
TGCTTTGTGAAAGTAATCGGAGCACAGAAATTGTTTCCATGGAAGAAATGCAGTGGATTCAGTTCTTTATTACATACAATCTTAACAGCC
AGTCTCCAGGAGTGCGGCAACAGATCTGTTCTCTTCTTAAAAAGTTGTTTTGTAGGATACAGGAAAGTTCTCAGGTACTTTATAAATTGG
AGCAGAGTAAATCCAAACGTGAACCAGAGAATGAGTTAACCAAACAGCACCCTTCTGTTTCTTTACAGCAGTATAAGAATTTCATGTCAT
CCATTTGTAACAGTCTTTTTGAAGCATTGTTTCCTGGATCTTCCTACTCGACTAGATTTTCAGCTTTAACCATTTTAGGTTCAATAGCTG
AAGTTTTTCATGTCCCAGAAGGCAGAATTTATACAGTATATCAGCTGAGTCATGATATTGATGTTGGTCGTTTCCAAACACTAATGGAAT
GTTTTACCAGCACTTTTGAAGACGTGAAAATTTTAGCATTTGATCTTCTGATGAAGTTATCAAAAACAGCTGTACATTTTCAGGATTCGG
GGAAACTGCAAGGCTTATTTCAGGCAGCATTGGAGCTCAGCACAAGCACCAAACCATACGACTGTGTGACAGCTTCCTACCTGCTGAACT
TCTTAATCTGGCAGGATGCTCTACCGTCATCCTTGTCTGCCTACTTAACTCAGCAAGTTGCATGTGATAATGGAGATAGGCCTGCTGCTG
TGGTGGAAAGGAACACATTAATGGTTATCAAATGCTTGATGGAAAATCTTGAGGAAGAAGTATCTCAGGCTGAAAATTCTCTGCTTCAGG
CAGCAGCAGCATTTCCAATGTATGGGCGAGTCCACTGTATAACAGGAGCTTTGCAGAAGTTATCTCTAAACAGCCTGCAGTTGGTGAGCG
AGTGGAGACCTGTGGTAGAGAAGCTCCTTTTGATGTCCTACAGGCTTTCCACTGTGGTGTCTCCAGTCATTCAGAGCTCATCCCCTGAAG
GCCTCATCCCAATGGACACTGATTCAGAGTCAGCAAGCCGCTTACAGATGATTCTGAATGAGATTCAGCCTCGAGATACTAATGATTATT
TTAACCAAGCCAAAATATTGAAAGAACATGATAGCTTTGATATGAAGGACTTGAATGCTAGTGTGGTGAATATTGATACTTCTACAGAAA
TCAAAGGTAAAGAAGTAAAAACATGTGATGTAACTGCGCAGATGGTGCTGGTATGTTGTTGGAGAAGTATGAAGGAAGTTGCTTTACTTT
TAGGCATGTTGTGCCAGCTTCTGCCCATGCAGCCTGTGCCAGAATCTTCTGATGGATTATTGACGGTGGAGCAGGTAAAAGAAATAGGAG
ATTACTTTAAACAACACCTTTTGCAGTCCAGGCACAGAGGAGCATTTGAATTGGCTTATACTGGTTTTGTGAAACTCACTGAAGTACTAA
ACAGGTGCCCAAATGTGAGTCTGCAAAAGCTGCCAGAACAGTGGCTATGGAGTGTTTTAGAGGAAATTAAATGCAGTGATCCTTCATCTA
AACTCTGTGCTACAAGGCGCAGTGCTGGAATTCCTTTCTACATACAGGCACTGTTGGCATCTGAACCAAAGAAAGGCAGAATGGATTTGT
TGAAAATAACAATGAAAGAGTTAATCTCTTTGGCTGGGCCTACAGATGACATACAGAGTACAGTCCCCCAGGTTCATGCTTTAAATATCC
TTAGAGCATTGTTCAGAGATACGCGCCTGGGAGAAAATATTATTCCTTATGTTGCTGATGGAGCTAAGGCTGCAATTCTGGGTTTTACAT
CACCGGTCTGGGCAGTGCGAAATTCATCCACACTTCTCTTTAGTGCCTTGATCACAAGAATTTTTGGAGTTAAAAGGGCAAAGGATGAAC
ATTCCAAAACAAATAGAATGACAGGGAGAGAGTTTTTCTCTCGTTTCCCAGAACTCTATCCTTTTCTTCTCAAACAGTTGGAAACTGTAG
CCAATACAGTAGACAGTGATATGGGAGAACCAAATCGTCATCCAAGCATGTTTCTCTTACTTTTGGTGTTGGAGAGACTCTACGCTTCCC
CGATGGATGGTACTTCTTCTGCTCTCAGCATGGGACCTTTTGTTCCCTTCATTATGAGGTGTGGTCACTCACCTGTCTACCACTCCCGTG
AAATGGCAGCTCGTGCCTTGGTCCCATTTGTTATGATAGATCACATTCCTAATACCATTCGAACTCTGTTGTCCACACTCCCCAGCTGCA
CTGACCAGTGTTTCCGGCAAAACCACATTCATGGGACACTTCTCCAGGATTCGGAAACTTCAGATACGAAATATCCCGCCTCATTTACAG
TGGGAGGTGCTGGATAGTTTACTAGTCCAGTATGGAGTGGTGGAGAGCTGTGAGCAAGTGAACACTGACTCGGAAACTGCAGTTGTAAAT
GTAACCTATTCCAGTAAGGACCAAGCTAGACAAGCACTAGACAAACTGAATGGATTTCAGTTAGAGAATTTCACCTTGAAAGTAGCCTAT
ATCCCTGATGAAATGGCCGCCCAGCAAAACCCCTTGCAGCAGCCCCGAGGTCGCCGGGGGCTTGGGCAGAGGGGCTCCTCAAGGCAGGGG
TCTCCAGGATCCGTATCCAAGCAGAAACCATGTGATTTGCCTCTGCGCCTGCTGGTTCCCACCCAATTTGTTGGAGCCATCATAGGAAAA
GAAGGTGCCACCATTCGGAACATCACCAAACAGACCCAGTCTAAAATCGATGTCCACCGTAAAGAAAATGCGGGGGCTGCTGAGAAGTCG
ATTACTATCCTCTCTACTCCTGAAGGCACCTCTGCGGCTTGTAAGTCTATTCTGGAGATTATGCATAAGGAAGCTCAAGATATAAAATTC
ACAGAAGAGATCCCCTTGAAGATTTTAGCTCATAATAACTTTGTTGGACGTCTTATTGGTAAAGAAGGAAGAAATCTTAAAAAAATTGAG
CAAGACACAGACACTAAAATCACGATATCTCCATTGCAGGAATTGACGCTGTATAATCCAGAACGCACTATTACAGTTAAAGGCAATGTT
GAGACATGTGCCAAAGCTGAGGAGGAGATCATGAAGAAAATCAGGGAGTCTTATGAAAATGATATTGCTTCTATGAATCTTCAAGCACAT
TTAATTCCTGGATTAAATCTGAACGCCTTGGGTCTGTTCCCACCCACTTCAGGGATGCCACCTCCCACCTCAGGGCCCCCTTCAGCCATG
ACTCCTCCCTACCCGCAGTTTGAGCAATCAGAAACGGAGACTGTTCATCTGTTTATCCCAGCTCTATCAGTCGGTGCCATCATCGGCAAG
CAGGGCCAGCACATCAAGCAGCTTTCTCGCTTTGCTGGAGCTTCAATTAAGATTGCTCCAGCGGAAGCACCAGATGCTAAAGTGAGGATG
GTGATTATCACTGGACCACCAGAGGCTCAGTTCAAGGCTCAGGGAAGAATTTATGGAAAAATTAAAGAAGAAAACTTTGTTAGTCCTAAA
GAAGAGGTGAAACTTGAAGCTCATATCAGAGTGCCATCCTTTGCTGCTGGCAGAGTTATTGGAAAAGGAGGCAAAACGGTGAATGAACTT
CAGAATTTGTCAAGTGCAGAAGTTGTTGTCCCTCGTGACCAGACACCTGATGAGAATGACCAAGTGGTTGTCAAAATAACTGGTCACTTC
TATGCTTGCCAGGTTGCCCAGAGAAAAATTCAGGAAATTCTGACTCAGGTAAAGCAGCACCAACAACAGAAGGCTCTGCAAAGTGGACCA
CCTCAGTCAAGACGGAAGTAAAGGCTCAGGAAACAGCCCACCACAGAGGCAGATGCCAAACCAAAGACAGATTGCTTAACCAACAGATGG
GCGCTGACCCCCTATCCAGAATCACATGCACAAGTTTTTACCTAGCCAGTTGTTTCTGAGGACCAGGCAACTTTTGAACTCCTGTCTCTG
TGAGAATGTATACTTTATGCTCTCTGAAATGTATGACACCCAGCTTTAAAACAAACAAACAAACAAACAAAAAAAGGGTGGGGGAGGGAG
GGAAAGAGAAGAGCTCTGCACTTCCCTTTGTTGTAGTCTCACAGTATAACAGATATTCTAATTCTTCTTAATATTCCCCCATAATGCCAG
AAATTGGCTTAATGATGCTTTCACTAAATTCATCAAATAGATTGCTCCTAAATCCAATTGTTAAAATTGGATCAGAATAATTATCACAGG
AACTTAAATGTTAAGCCATTAGCATAGAAAAACTGTTCTCAGTTTTATTTTTACCTAACACTAACATGAGTAACCTAAGGGAAGTGCTGA
ATGGTGTTGGCAGGGGTATTAAACGTGCATTTTTACTCAACTACCTCAGGTATTCAGTAATACAATGAAAAGCAAAATTGTTCCTTTTTT
TTGAAAATTTTATATACTTTATAATGATAGAAGTCCAACCGTTTTTTAAAAAATAAATTTAAAATTTAACAGCAATCAGCTAACAGGCAA
ATTAAGATTTTTACTTCTGGCTGGTGACAGTAAAGCTGGAAAATTAATTTCAGGGTTTTTTGAGGCTTTTGACACAGTTATTAGTTAAAT
CAAATGTTCAAAAATACGGAGCAGTGCCTAGTATCTGGAGAGCAGCACTACCATTTATTCTTTCATTTATAGTTGGGAAAGTTTTTGACG
GTACTAACAAAGTGGTCGCAGGAGATTTTGGAACGGCTGGTTTAAATGGCTTCAGGAGACTTCAGTTTTTTGTTTAGCTACATGATTGAA
TGCATAATAAATGCTTTGTGCTTCTGACTATCAATACCTAAAGAAAGTGCATCAGTGAAGAGATGCAAGACTTTCAACTGACTGGCAAAA
AGCAAGCTTTAGCTTGTCTTATAGGATGCTTAGTTTGCCACTACACTTCAGACCAATGGGACAGTCATAGATGGTGTGACAGTGTTTAAA
CGCAACAAAAGGCTACATTTCCATGGGGCCAGCACTGTCATGAGCCTCACTAAGCTATTTTGAAGATTTTTAAGCACTGATAAATTAAAA
AAAAAAAATTAGACTCCACCTTAAGTAGTAAAGTATAACAGGATTTCTGTATACTGTGCAATCAGTTCTTTGAAAAAAAAGTCAAAAGAT
AGAGAATACAAGAAAAGTTTTTGGGATATAATTTGAATGACTGTGAAAACATATGACCTTTGATAACGAACTCATTTGCTCACTCCTTGA
CAGCAAAGCCCAGTACGTACAATTGTGTTGGGTGTGGGTGGTCTCCAAGGCCACGCTGCTCTCTGAATTGATTTTTTGAGTTTTGTTTGT
AAGATGATCACAGTCATGTTACACTGATCTAAAGGACATATATATAACCCTTTAAAAAAAAAATCACTGCCTCATTCTTATTTCAAGATG
AATTTCTATACAGACTAGATGTTTTTCTGAAGATCAATTAGACATTTTGAAAATGATTTAAAGTGTTTTCCTTAATGTTCTCTGAAAACA
AGTTTCTTTTGTAGTTTTAACCAAAAAAGTGCCCTTTTTGTCACTGGATTCTCCTAGCATTCATGATTTTTTTTTCATACAATGAATTAA
AATTGCTAAAATCATGGACTGGCTTTCTGGTTGGATTTCAGGTAAGATGTGTTTAAGGCCAGAGCTTTTCTCAGTATTTGATTTTTTTCC
CCAATATTTGATTTTTTAAAAATATACACATAGGTGCTGCATTTATATCTGCTGGTTTAAATTCTGTCATATTTCACTTCTAGCCTTTTA
GTATGGCAAATCATATTTTACTTTTACTTAAGCATTTGTAATTTGGAGTATCTGGTACTAGCTAAGAAATAATTCTATAATTGAGTTTTG
TACTCACCATATATGGATCATTCCTCATGTATAATGTGCCCCAAATGCAGCTTCATTTTCCAGATACCTTGACGCAGAATAAATTTTTTC

>90565_90565_2_THADA-IGF2BP3_THADA_chr2_43625110_ENST00000405975_IGF2BP3_chr7_23458443_ENST00000258729_length(amino acids)=1428AA_BP=1406
MGVKKKKEMQVAALTICHQDLETLKSFADVEGKNLASLLLHCVQLTDGVSQIHYIKQIVPLLEKADKNGMCDPTIQSCLDILAGIYLSLS
LKNPLKKVLASSLNSLPDFFLPEAMHRFTSRLQEELNTTDLYSYRKVTDNISSCMENFNLGRASVNNLLKNVLHFLQKSLIEILEENRKC
AGNHIIQTQLMNDLLVGIRVSMMLVQKVQDFQGNLWKTSDSPIWQNMCGLLSIFTKVLSDDDLLQTVQSTSGLAIILFIKTMFHPSEKIP
HLISSVLLRSVDCTSVPEWFMSSCRSLCCGDISQSAVLFLCQGTLAMLDWQNGSMGRSGEALLLDTAHVLFTLSSQIKEPTLEMFLSRIL
ASWTNSAIQVLESSSPSLTDSLNGNSSIVGRLLEYVYTHWEHPLDALRHQTKIMFKNLLQMHRLTVEGADFVPDPFFVELTESLLRLEWH
IKGKYTCLGCLVECIGVEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFRNHKSHLKSQTAESSWIDQWHETWVSPLLFILCEGNLD
QKSYVIDYYLPKLLSYSPESLQYMVKILQTSIDAKTGQEQSFPSLGSCNSRGALGALMACLRIARAHGHLQSATDTWENLVSDARIKQGL
IHQHCQVRIDTLGLLCESNRSTEIVSMEEMQWIQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQSKSKREPENELTKQH
PSVSLQQYKNFMSSICNSLFEALFPGSSYSTRFSALTILGSIAEVFHVPEGRIYTVYQLSHDIDVGRFQTLMECFTSTFEDVKILAFDLL
MKLSKTAVHFQDSGKLQGLFQAALELSTSTKPYDCVTASYLLNFLIWQDALPSSLSAYLTQQVACDNGDRPAAVVERNTLMVIKCLMENL
EEEVSQAENSLLQAAAAFPMYGRVHCITGALQKLSLNSLQLVSEWRPVVEKLLLMSYRLSTVVSPVIQSSSPEGLIPMDTDSESASRLQM
ILNEIQPRDTNDYFNQAKILKEHDSFDMKDLNASVVNIDTSTEIKGKEVKTCDVTAQMVLVCCWRSMKEVALLLGMLCQLLPMQPVPESS
DGLLTVEQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEVLNRCPNVSLQKLPEQWLWSVLEEIKCSDPSSKLCATRRSAGIPFYIQA
LLASEPKKGRMDLLKITMKELISLAGPTDDIQSTVPQVHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSAL
ITRIFGVKRAKDEHSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDMGEPNRHPSMFLLLLVLERLYASPMDGTSSALSMGPFVPF

--------------------------------------------------------------
>90565_90565_3_THADA-IGF2BP3_THADA_chr2_43625110_ENST00000415080_IGF2BP3_chr7_23458443_ENST00000258729_length(transcript)=7937nt_BP=4280nt
GACCCGGTAGTCGACCGTGGACCGCGCTGCGAGCCTCGGAGACGCCGTAGAAGGAGACCTGCTTCCGGGACTGGACCAGGCGCCTGCGAC
TCTTCTCAGACGCCGACGTGCACGAGTGACTACTATTAATTCTATTTAAAATGGGTGTAAAGAAGAAGAAAGAAATGCAAGTTGCTGCGC
TGACCATTTGCCATCAGGACCTTGAAACTTTGAAATCTTTTGCTGATGTGGAAGGGAAAAATCTAGCTTCTTTGCTGTTACATTGTGTGC
AACTCACGGATGGAGTGTCACAAATCCATTATATTAAACAGATTGTGCCTCTGCTGGAGAAAGCAGATAAAAATGGCATGTGTGATCCCA
CTATTCAAAGTTGTTTGGATATCTTAGCAGGCATTTATCTTTCTTTGAGTCTAAAGAATCCCTTGAAGAAAGTATTGGCAAGCTCACTAA
ATAGCCTGCCTGATTTTTTTCTACCTGAGGCTATGCACCGTTTTACTTCTCGTCTTCAGGAAGAATTGAATACTACTGACTTATACTCTT
ACAGGAAAGTTACTGACAATATTTCTTCCTGTATGGAGAACTTTAACTTGGGTAGAGCAAGTGTTAATAATCTGCTTAAAAATGTGCTTC
ATTTTCTGCAGAAGAGTTTAATTGAAATCCTGGAAGAAAATAGAAAATGTGCTGGAAATCATATTATTCAAACACAGTTGATGAATGACT
TACTGGTAGGCATTAGAGTTTCAATGATGTTAGTACAGAAAGTACAAGATTTCCAGGGAAATCTTTGGAAGACTTCCGATTCTCCCATAT
GGCAAAATATGTGTGGATTGCTGAGTATTTTTACCAAGGTTTTAAGCGATGATGATCTGTTACAGACTGTACAGAGCACATCTGGATTAG
CTATTATTCTTTTTATTAAGACTATGTTTCACCCGTCTGAAAAGATTCCTCATTTGATTAGCAGTGTGCTGCTTCGTTCAGTGGACTGCA
CCAGTGTCCCCGAGTGGTTTATGAGCAGCTGCAGGAGCCTCTGTTGTGGTGACATCTCTCAGTCAGCTGTCTTATTCCTCTGTCAGGGGA
CACTTGCCATGTTGGACTGGCAGAACGGAAGCATGGGTCGGAGTGGGGAGGCCCTGCTCTTGGATACTGCACATGTTTTGTTCACCTTGA
GTTCACAGATTAAAGAGCCAACGCTGGAAATGTTTCTGTCTAGAATCTTAGCATCCTGGACTAATTCAGCCATACAAGTCCTTGAATCAA
GTTCCCCGAGCCTAACGGACAGCCTGAATGGGAATTCAAGTATAGTTGGGAGACTTTTGGAATATGTCTATACCCATTGGGAACATCCAT
TGGATGCTCTGAGACACCAAACCAAAATCATGTTCAAAAACCTTCTCCAAATGCACCGGCTCACTGTGGAAGGTGCAGATTTCGTCCCTG
ATCCTTTCTTTGTGGAATTGACTGAGAGTCTTTTACGATTGGAATGGCATATTAAAGGAAAGTACACGTGCCTTGGTTGTTTGGTAGAGT
GCATAGGAGTTGAACATATTTTGGCTATAGATAAAACTATTCCATCTCAAATCTTAGAGGTGATGGGAGACCAGTCATTGGTACCTTATG
CAAGTGACCTCTTGGAAACCATGTTTAGAAATCATAAGAGTCATTTGAAATCCCAGACTGCTGAGAGTTCTTGGATTGACCAGTGGCATG
AGACTTGGGTTTCTCCTCTCCTTTTTATATTGTGTGAAGGAAACTTGGATCAAAAATCTTACGTGATTGATTATTACTTGCCAAAATTAT
TAAGTTACAGCCCTGAAAGCTTACAGTACATGGTAAAGATTCTTCAGACTTCTATTGATGCTAAAACTGGACAAGAGCAATCTTTCCCAT
CCTTAGGGTCTTGTAATAGCAGGGGGGCTCTGGGAGCTTTGATGGCATGTCTGCGAATAGCTAGAGCTCATGGACATCTTCAGTCTGCAA
CTGATACCTGGGAGAACCTCGTGTCTGATGCAAGAATAAAGCAAGGCTTAATTCATCAGCATTGCCAAGTAAGGATAGATACATTAGGCT
TGCTTTGTGAAAGTAATCGGAGCACAGAAATTGTTTCCATGGAAGAAATGCAGTGGATTCAGTTCTTTATTACATACAATCTTAACAGCC
AGTCTCCAGGAGTGCGGCAACAGATCTGTTCTCTTCTTAAAAAGTTGTTTTGTAGGATACAGGAAAGTTCTCAGGTACTTTATAAATTGG
AGCAGAGTAAATCCAAACGTGAACCAGAGAATGAGTTAACCAAACAGCACCCTTCTGTTTCTTTACAGCAGTATAAGAATTTCATGTCAT
CCATTTGTAACAGTCTTTTTGAAGCATTGTTTCCTGGATCTTCCTACTCGACTAGATTTTCAGCTTTAACCATTTTAGGTTCAATAGCTG
AAGTTTTTCATGTCCCAGAAGGCAGAATTTATACAGTATATCAGCTGAGTCATGATATTGATGTTGGTCGTTTCCAAACACTAATGGAAT
GTTTTACCAGCACTTTTGAAGACGTGAAAATTTTAGCATTTGATCTTCTGATGAAGTTATCAAAAACAGCTGTACATTTTCAGGATTCGG
GGAAACTGCAAGGCTTATTTCAGGCAGCATTGGAGCTCAGCACAAGCACCAAACCATACGACTGTGTGACAGCTTCCTACCTGCTGAACT
TCTTAATCTGGCAGGATGCTCTACCGTCATCCTTGTCTGCCTACTTAACTCAGCAAGTTGCATGTGATAATGGAGATAGGCCTGCTGCTG
TGGTGGAAAGGAACACATTAATGGTTATCAAATGCTTGATGGAAAATCTTGAGGAAGAAGTATCTCAGGCTGAAAATTCTCTGCTTCAGG
CAGCAGCAGCATTTCCAATGTATGGGCGAGTCCACTGTATAACAGGAGCTTTGCAGAAGTTATCTCTAAACAGCCTGCAGTTGGTGAGCG
AGTGGAGACCTGTGGTAGAGAAGCTCCTTTTGATGTCCTACAGGCTTTCCACTGTGGTGTCTCCAGTCATTCAGAGCTCATCCCCTGAAG
GCCTCATCCCAATGGACACTGATTCAGAGTCAGCAAGCCGCTTACAGATGATTCTGAATGAGATTCAGCCTCGAGATACTAATGATTATT
TTAACCAAGCCAAAATATTGAAAGAACATGATAGCTTTGATATGAAGGACTTGAATGCTAGTGTGGTGAATATTGATACTTCTACAGAAA
TCAAAGGTAAAGAAGTAAAAACATGTGATGTAACTGCGCAGATGGTGCTGGTATGTTGTTGGAGAAGTATGAAGGAAGTTGCTTTACTTT
TAGGCATGTTGTGCCAGCTTCTGCCCATGCAGCCTGTGCCAGAATCTTCTGATGGATTATTGACGGTGGAGCAGGTAAAAGAAATAGGAG
ATTACTTTAAACAACACCTTTTGCAGTCCAGGCACAGAGGAGCATTTGAATTGGCTTATACTGGTTTTGTGAAACTCACTGAAGTACTAA
ACAGGTGCCCAAATGTGAGTCTGCAAAAGCTGCCAGAACAGTGGCTATGGAGTGTTTTAGAGGAAATTAAATGCAGTGATCCTTCATCTA
AACTCTGTGCTACAAGGCGCAGTGCTGGAATTCCTTTCTACATACAGGCACTGTTGGCATCTGAACCAAAGAAAGGCAGAATGGATTTGT
TGAAAATAACAATGAAAGAGTTAATCTCTTTGGCTGGGCCTACAGATGACATACAGAGTACAGTCCCCCAGGTTCATGCTTTAAATATCC
TTAGAGCATTGTTCAGAGATACGCGCCTGGGAGAAAATATTATTCCTTATGTTGCTGATGGAGCTAAGGCTGCAATTCTGGGTTTTACAT
CACCGGTCTGGGCATCTCAAATGACAGGGAGAGAGTTTTTCTCTCGTTTCCCAGAACTCTATCCTTTTCTTCTCAAACAGTTGGAAACTG
TAGCCAATACAGTAGACAGTGATATGGGAGAACCAAATCGTCATCCAAGCATGTTTCTCTTACTTTTGGTGTTGGAGAGACTCTACGCTT
CCCCGATGGATGGTACTTCTTCTGCTCTCAGCATGGGACCTTTTGTTCCCTTCATTATGAGGTGTGGTCACTCACCTGTCTACCACTCCC
GTGAAATGGCAGCTCGTGCCTTGGTCCCATTTGTTATGATAGATCACATTCCTAATACCATTCGAACTCTGTTGTCCACACTCCCCAGCT
GCACTGACCAGTGTTTCCGGCAAAACCACATTCATGGGACACTTCTCCAGGATTCGGAAACTTCAGATACGAAATATCCCGCCTCATTTA
CAGTGGGAGGTGCTGGATAGTTTACTAGTCCAGTATGGAGTGGTGGAGAGCTGTGAGCAAGTGAACACTGACTCGGAAACTGCAGTTGTA
AATGTAACCTATTCCAGTAAGGACCAAGCTAGACAAGCACTAGACAAACTGAATGGATTTCAGTTAGAGAATTTCACCTTGAAAGTAGCC
TATATCCCTGATGAAATGGCCGCCCAGCAAAACCCCTTGCAGCAGCCCCGAGGTCGCCGGGGGCTTGGGCAGAGGGGCTCCTCAAGGCAG
GGGTCTCCAGGATCCGTATCCAAGCAGAAACCATGTGATTTGCCTCTGCGCCTGCTGGTTCCCACCCAATTTGTTGGAGCCATCATAGGA
AAAGAAGGTGCCACCATTCGGAACATCACCAAACAGACCCAGTCTAAAATCGATGTCCACCGTAAAGAAAATGCGGGGGCTGCTGAGAAG
TCGATTACTATCCTCTCTACTCCTGAAGGCACCTCTGCGGCTTGTAAGTCTATTCTGGAGATTATGCATAAGGAAGCTCAAGATATAAAA
TTCACAGAAGAGATCCCCTTGAAGATTTTAGCTCATAATAACTTTGTTGGACGTCTTATTGGTAAAGAAGGAAGAAATCTTAAAAAAATT
GAGCAAGACACAGACACTAAAATCACGATATCTCCATTGCAGGAATTGACGCTGTATAATCCAGAACGCACTATTACAGTTAAAGGCAAT
GTTGAGACATGTGCCAAAGCTGAGGAGGAGATCATGAAGAAAATCAGGGAGTCTTATGAAAATGATATTGCTTCTATGAATCTTCAAGCA
CATTTAATTCCTGGATTAAATCTGAACGCCTTGGGTCTGTTCCCACCCACTTCAGGGATGCCACCTCCCACCTCAGGGCCCCCTTCAGCC
ATGACTCCTCCCTACCCGCAGTTTGAGCAATCAGAAACGGAGACTGTTCATCTGTTTATCCCAGCTCTATCAGTCGGTGCCATCATCGGC
AAGCAGGGCCAGCACATCAAGCAGCTTTCTCGCTTTGCTGGAGCTTCAATTAAGATTGCTCCAGCGGAAGCACCAGATGCTAAAGTGAGG
ATGGTGATTATCACTGGACCACCAGAGGCTCAGTTCAAGGCTCAGGGAAGAATTTATGGAAAAATTAAAGAAGAAAACTTTGTTAGTCCT
AAAGAAGAGGTGAAACTTGAAGCTCATATCAGAGTGCCATCCTTTGCTGCTGGCAGAGTTATTGGAAAAGGAGGCAAAACGGTGAATGAA
CTTCAGAATTTGTCAAGTGCAGAAGTTGTTGTCCCTCGTGACCAGACACCTGATGAGAATGACCAAGTGGTTGTCAAAATAACTGGTCAC
TTCTATGCTTGCCAGGTTGCCCAGAGAAAAATTCAGGAAATTCTGACTCAGGTAAAGCAGCACCAACAACAGAAGGCTCTGCAAAGTGGA
CCACCTCAGTCAAGACGGAAGTAAAGGCTCAGGAAACAGCCCACCACAGAGGCAGATGCCAAACCAAAGACAGATTGCTTAACCAACAGA
TGGGCGCTGACCCCCTATCCAGAATCACATGCACAAGTTTTTACCTAGCCAGTTGTTTCTGAGGACCAGGCAACTTTTGAACTCCTGTCT
CTGTGAGAATGTATACTTTATGCTCTCTGAAATGTATGACACCCAGCTTTAAAACAAACAAACAAACAAACAAAAAAAGGGTGGGGGAGG
GAGGGAAAGAGAAGAGCTCTGCACTTCCCTTTGTTGTAGTCTCACAGTATAACAGATATTCTAATTCTTCTTAATATTCCCCCATAATGC
CAGAAATTGGCTTAATGATGCTTTCACTAAATTCATCAAATAGATTGCTCCTAAATCCAATTGTTAAAATTGGATCAGAATAATTATCAC
AGGAACTTAAATGTTAAGCCATTAGCATAGAAAAACTGTTCTCAGTTTTATTTTTACCTAACACTAACATGAGTAACCTAAGGGAAGTGC
TGAATGGTGTTGGCAGGGGTATTAAACGTGCATTTTTACTCAACTACCTCAGGTATTCAGTAATACAATGAAAAGCAAAATTGTTCCTTT
TTTTTGAAAATTTTATATACTTTATAATGATAGAAGTCCAACCGTTTTTTAAAAAATAAATTTAAAATTTAACAGCAATCAGCTAACAGG
CAAATTAAGATTTTTACTTCTGGCTGGTGACAGTAAAGCTGGAAAATTAATTTCAGGGTTTTTTGAGGCTTTTGACACAGTTATTAGTTA
AATCAAATGTTCAAAAATACGGAGCAGTGCCTAGTATCTGGAGAGCAGCACTACCATTTATTCTTTCATTTATAGTTGGGAAAGTTTTTG
ACGGTACTAACAAAGTGGTCGCAGGAGATTTTGGAACGGCTGGTTTAAATGGCTTCAGGAGACTTCAGTTTTTTGTTTAGCTACATGATT
GAATGCATAATAAATGCTTTGTGCTTCTGACTATCAATACCTAAAGAAAGTGCATCAGTGAAGAGATGCAAGACTTTCAACTGACTGGCA
AAAAGCAAGCTTTAGCTTGTCTTATAGGATGCTTAGTTTGCCACTACACTTCAGACCAATGGGACAGTCATAGATGGTGTGACAGTGTTT
AAACGCAACAAAAGGCTACATTTCCATGGGGCCAGCACTGTCATGAGCCTCACTAAGCTATTTTGAAGATTTTTAAGCACTGATAAATTA
AAAAAAAAAAATTAGACTCCACCTTAAGTAGTAAAGTATAACAGGATTTCTGTATACTGTGCAATCAGTTCTTTGAAAAAAAAGTCAAAA
GATAGAGAATACAAGAAAAGTTTTTGGGATATAATTTGAATGACTGTGAAAACATATGACCTTTGATAACGAACTCATTTGCTCACTCCT
TGACAGCAAAGCCCAGTACGTACAATTGTGTTGGGTGTGGGTGGTCTCCAAGGCCACGCTGCTCTCTGAATTGATTTTTTGAGTTTTGTT
TGTAAGATGATCACAGTCATGTTACACTGATCTAAAGGACATATATATAACCCTTTAAAAAAAAAATCACTGCCTCATTCTTATTTCAAG
ATGAATTTCTATACAGACTAGATGTTTTTCTGAAGATCAATTAGACATTTTGAAAATGATTTAAAGTGTTTTCCTTAATGTTCTCTGAAA
ACAAGTTTCTTTTGTAGTTTTAACCAAAAAAGTGCCCTTTTTGTCACTGGATTCTCCTAGCATTCATGATTTTTTTTTCATACAATGAAT
TAAAATTGCTAAAATCATGGACTGGCTTTCTGGTTGGATTTCAGGTAAGATGTGTTTAAGGCCAGAGCTTTTCTCAGTATTTGATTTTTT
TCCCCAATATTTGATTTTTTAAAAATATACACATAGGTGCTGCATTTATATCTGCTGGTTTAAATTCTGTCATATTTCACTTCTAGCCTT
TTAGTATGGCAAATCATATTTTACTTTTACTTAAGCATTTGTAATTTGGAGTATCTGGTACTAGCTAAGAAATAATTCTATAATTGAGTT
TTGTACTCACCATATATGGATCATTCCTCATGTATAATGTGCCCCAAATGCAGCTTCATTTTCCAGATACCTTGACGCAGAATAAATTTT

>90565_90565_3_THADA-IGF2BP3_THADA_chr2_43625110_ENST00000415080_IGF2BP3_chr7_23458443_ENST00000258729_length(amino acids)=1399AA_BP=1377
MGVKKKKEMQVAALTICHQDLETLKSFADVEGKNLASLLLHCVQLTDGVSQIHYIKQIVPLLEKADKNGMCDPTIQSCLDILAGIYLSLS
LKNPLKKVLASSLNSLPDFFLPEAMHRFTSRLQEELNTTDLYSYRKVTDNISSCMENFNLGRASVNNLLKNVLHFLQKSLIEILEENRKC
AGNHIIQTQLMNDLLVGIRVSMMLVQKVQDFQGNLWKTSDSPIWQNMCGLLSIFTKVLSDDDLLQTVQSTSGLAIILFIKTMFHPSEKIP
HLISSVLLRSVDCTSVPEWFMSSCRSLCCGDISQSAVLFLCQGTLAMLDWQNGSMGRSGEALLLDTAHVLFTLSSQIKEPTLEMFLSRIL
ASWTNSAIQVLESSSPSLTDSLNGNSSIVGRLLEYVYTHWEHPLDALRHQTKIMFKNLLQMHRLTVEGADFVPDPFFVELTESLLRLEWH
IKGKYTCLGCLVECIGVEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFRNHKSHLKSQTAESSWIDQWHETWVSPLLFILCEGNLD
QKSYVIDYYLPKLLSYSPESLQYMVKILQTSIDAKTGQEQSFPSLGSCNSRGALGALMACLRIARAHGHLQSATDTWENLVSDARIKQGL
IHQHCQVRIDTLGLLCESNRSTEIVSMEEMQWIQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQSKSKREPENELTKQH
PSVSLQQYKNFMSSICNSLFEALFPGSSYSTRFSALTILGSIAEVFHVPEGRIYTVYQLSHDIDVGRFQTLMECFTSTFEDVKILAFDLL
MKLSKTAVHFQDSGKLQGLFQAALELSTSTKPYDCVTASYLLNFLIWQDALPSSLSAYLTQQVACDNGDRPAAVVERNTLMVIKCLMENL
EEEVSQAENSLLQAAAAFPMYGRVHCITGALQKLSLNSLQLVSEWRPVVEKLLLMSYRLSTVVSPVIQSSSPEGLIPMDTDSESASRLQM
ILNEIQPRDTNDYFNQAKILKEHDSFDMKDLNASVVNIDTSTEIKGKEVKTCDVTAQMVLVCCWRSMKEVALLLGMLCQLLPMQPVPESS
DGLLTVEQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEVLNRCPNVSLQKLPEQWLWSVLEEIKCSDPSSKLCATRRSAGIPFYIQA
LLASEPKKGRMDLLKITMKELISLAGPTDDIQSTVPQVHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWASQMTGREFFSRF
PELYPFLLKQLETVANTVDSDMGEPNRHPSMFLLLLVLERLYASPMDGTSSALSMGPFVPFIMRCGHSPVYHSREMAARALVPFVMIDHI

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Fusion Gene PPI Analysis for THADA-IGF2BP3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for THADA-IGF2BP3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for THADA-IGF2BP3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource