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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:THSD4-WARS (FusionGDB2 ID:90781)

Fusion Gene Summary for THSD4-WARS

check button Fusion gene summary
Fusion gene informationFusion gene name: THSD4-WARS
Fusion gene ID: 90781
HgeneTgene
Gene symbol

THSD4

WARS

Gene ID

79875

7453

Gene namethrombospondin type 1 domain containing 4tryptophanyl-tRNA synthetase 1
SynonymsADAMTSL-6|ADAMTSL6|FVSY9334|PRO34005GAMMA-2|HMN9|IFI53|IFP53|WARS
Cytomap

15q23

14q32.2

Type of geneprotein-codingprotein-coding
Descriptionthrombospondin type-1 domain-containing protein 4A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6ADAMTS-like protein 6thrombospondin, type I, domain containing 4tryptophan--tRNA ligase, cytoplasmicepididymis secretory sperm binding proteinhWRSinterferon-induced protein 53trpRStryptophan tRNA ligase 1, cytoplasmic
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000357769, ENST00000261862, 
ENST00000355327, ENST00000567838, 
ENST00000554084, ENST00000344102, 
ENST00000355338, ENST00000358655, 
ENST00000392882, ENST00000556645, 
ENST00000557135, 
Fusion gene scores* DoF score21 X 27 X 8=453613 X 14 X 8=1456
# samples 3121
** MAII scorelog2(31/4536*10)=-3.87108051966799
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(21/1456*10)=-2.79354912253257
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: THSD4 [Title/Abstract] AND WARS [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTHSD4(71839820)-WARS(100803539), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneWARS

GO:0001933

negative regulation of protein phosphorylation

22504299

TgeneWARS

GO:0006469

negative regulation of protein kinase activity

22504299

TgeneWARS

GO:0010628

positive regulation of gene expression

22504299

TgeneWARS

GO:0010835

regulation of protein ADP-ribosylation

22504299

TgeneWARS

GO:0045765

regulation of angiogenesis

11773625|11773626


check buttonFusion gene breakpoints across THSD4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across WARS (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-63-A5MP-01ATHSD4chr15

71839819

+WARSchr14

100803538

-
ChimerDB4LUSCTCGA-63-A5MP-01ATHSD4chr15

71839820

-WARSchr14

100803539

-
ChimerDB4LUSCTCGA-63-A5MP-01ATHSD4chr15

71839820

+WARSchr14

100803539

-
ChimerDB4LUSCTCGA-63-A5MPTHSD4chr15

71839820

+WARSchr14

100803539

-


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Fusion Gene ORF analysis for THSD4-WARS

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000357769ENST00000554084THSD4chr15

71839819

+WARSchr14

100803538

-
5CDS-intronENST00000357769ENST00000554084THSD4chr15

71839820

+WARSchr14

100803539

-
In-frameENST00000357769ENST00000344102THSD4chr15

71839819

+WARSchr14

100803538

-
In-frameENST00000357769ENST00000344102THSD4chr15

71839820

+WARSchr14

100803539

-
In-frameENST00000357769ENST00000355338THSD4chr15

71839819

+WARSchr14

100803538

-
In-frameENST00000357769ENST00000355338THSD4chr15

71839820

+WARSchr14

100803539

-
In-frameENST00000357769ENST00000358655THSD4chr15

71839819

+WARSchr14

100803538

-
In-frameENST00000357769ENST00000358655THSD4chr15

71839820

+WARSchr14

100803539

-
In-frameENST00000357769ENST00000392882THSD4chr15

71839819

+WARSchr14

100803538

-
In-frameENST00000357769ENST00000392882THSD4chr15

71839820

+WARSchr14

100803539

-
In-frameENST00000357769ENST00000556645THSD4chr15

71839819

+WARSchr14

100803538

-
In-frameENST00000357769ENST00000556645THSD4chr15

71839820

+WARSchr14

100803539

-
In-frameENST00000357769ENST00000557135THSD4chr15

71839819

+WARSchr14

100803538

-
In-frameENST00000357769ENST00000557135THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000261862ENST00000344102THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000261862ENST00000344102THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000261862ENST00000355338THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000261862ENST00000355338THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000261862ENST00000358655THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000261862ENST00000358655THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000261862ENST00000392882THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000261862ENST00000392882THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000261862ENST00000556645THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000261862ENST00000556645THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000261862ENST00000557135THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000261862ENST00000557135THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000355327ENST00000344102THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000355327ENST00000344102THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000355327ENST00000355338THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000355327ENST00000355338THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000355327ENST00000358655THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000355327ENST00000358655THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000355327ENST00000392882THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000355327ENST00000392882THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000355327ENST00000556645THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000355327ENST00000556645THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000355327ENST00000557135THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000355327ENST00000557135THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000567838ENST00000344102THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000567838ENST00000344102THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000567838ENST00000355338THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000567838ENST00000355338THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000567838ENST00000358655THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000567838ENST00000358655THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000567838ENST00000392882THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000567838ENST00000392882THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000567838ENST00000556645THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000567838ENST00000556645THSD4chr15

71839820

+WARSchr14

100803539

-
intron-3CDSENST00000567838ENST00000557135THSD4chr15

71839819

+WARSchr14

100803538

-
intron-3CDSENST00000567838ENST00000557135THSD4chr15

71839820

+WARSchr14

100803539

-
intron-intronENST00000261862ENST00000554084THSD4chr15

71839819

+WARSchr14

100803538

-
intron-intronENST00000261862ENST00000554084THSD4chr15

71839820

+WARSchr14

100803539

-
intron-intronENST00000355327ENST00000554084THSD4chr15

71839819

+WARSchr14

100803538

-
intron-intronENST00000355327ENST00000554084THSD4chr15

71839820

+WARSchr14

100803539

-
intron-intronENST00000567838ENST00000554084THSD4chr15

71839819

+WARSchr14

100803538

-
intron-intronENST00000567838ENST00000554084THSD4chr15

71839820

+WARSchr14

100803539

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000357769THSD4chr1571839820+ENST00000392882WARSchr14100803539-1636246174548124
ENST00000357769THSD4chr1571839820+ENST00000358655WARSchr14100803539-1622246174548124
ENST00000357769THSD4chr1571839820+ENST00000355338WARSchr14100803539-1606246174548124
ENST00000357769THSD4chr1571839820+ENST00000344102WARSchr14100803539-1596246174548124
ENST00000357769THSD4chr1571839820+ENST00000557135WARSchr14100803539-945246174548124
ENST00000357769THSD4chr1571839820+ENST00000556645WARSchr14100803539-931246174548124
ENST00000357769THSD4chr1571839819+ENST00000392882WARSchr14100803538-1636246174548124
ENST00000357769THSD4chr1571839819+ENST00000358655WARSchr14100803538-1622246174548124
ENST00000357769THSD4chr1571839819+ENST00000355338WARSchr14100803538-1606246174548124
ENST00000357769THSD4chr1571839819+ENST00000344102WARSchr14100803538-1596246174548124
ENST00000357769THSD4chr1571839819+ENST00000557135WARSchr14100803538-945246174548124
ENST00000357769THSD4chr1571839819+ENST00000556645WARSchr14100803538-931246174548124

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000357769ENST00000392882THSD4chr1571839820+WARSchr14100803539-0.0084409250.99155915
ENST00000357769ENST00000358655THSD4chr1571839820+WARSchr14100803539-0.0088837360.9911163
ENST00000357769ENST00000355338THSD4chr1571839820+WARSchr14100803539-0.0089187820.9910813
ENST00000357769ENST00000344102THSD4chr1571839820+WARSchr14100803539-0.008216460.9917835
ENST00000357769ENST00000557135THSD4chr1571839820+WARSchr14100803539-0.0132416870.9867583
ENST00000357769ENST00000556645THSD4chr1571839820+WARSchr14100803539-0.0145481260.9854519
ENST00000357769ENST00000392882THSD4chr1571839819+WARSchr14100803538-0.0084409250.99155915
ENST00000357769ENST00000358655THSD4chr1571839819+WARSchr14100803538-0.0088837360.9911163
ENST00000357769ENST00000355338THSD4chr1571839819+WARSchr14100803538-0.0089187820.9910813
ENST00000357769ENST00000344102THSD4chr1571839819+WARSchr14100803538-0.008216460.9917835
ENST00000357769ENST00000557135THSD4chr1571839819+WARSchr14100803538-0.0132416870.9867583
ENST00000357769ENST00000556645THSD4chr1571839819+WARSchr14100803538-0.0145481260.9854519

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Fusion Genomic Features for THSD4-WARS


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for THSD4-WARS


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:71839820/chr14:100803539)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneWARSchr15:71839819chr14:100803538ENST00000344102710349_353330431.0MotifNote='KMSKS' region
TgeneWARSchr15:71839819chr14:100803538ENST00000358655710349_353330431.0MotifNote='KMSKS' region
TgeneWARSchr15:71839819chr14:100803538ENST00000556645811349_353330431.0MotifNote='KMSKS' region
TgeneWARSchr15:71839820chr14:100803539ENST00000344102710349_353330431.0MotifNote='KMSKS' region
TgeneWARSchr15:71839820chr14:100803539ENST00000358655710349_353330431.0MotifNote='KMSKS' region
TgeneWARSchr15:71839820chr14:100803539ENST00000556645811349_353330431.0MotifNote='KMSKS' region

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTHSD4chr15:71839819chr14:100803538ENST00000261862+11753_30701019.0DomainTSP type-1 1
HgeneTHSD4chr15:71839819chr14:100803538ENST00000261862+117676_73701019.0DomainTSP type-1 2
HgeneTHSD4chr15:71839819chr14:100803538ENST00000261862+117739_79201019.0DomainTSP type-1 3
HgeneTHSD4chr15:71839819chr14:100803538ENST00000261862+117793_85101019.0DomainTSP type-1 4
HgeneTHSD4chr15:71839819chr14:100803538ENST00000261862+117852_91101019.0DomainTSP type-1 5
HgeneTHSD4chr15:71839819chr14:100803538ENST00000261862+117912_96801019.0DomainTSP type-1 6
HgeneTHSD4chr15:71839819chr14:100803538ENST00000261862+117971_100801019.0DomainPLAC
HgeneTHSD4chr15:71839819chr14:100803538ENST00000355327+11853_30701019.0DomainTSP type-1 1
HgeneTHSD4chr15:71839819chr14:100803538ENST00000355327+118676_73701019.0DomainTSP type-1 2
HgeneTHSD4chr15:71839819chr14:100803538ENST00000355327+118739_79201019.0DomainTSP type-1 3
HgeneTHSD4chr15:71839819chr14:100803538ENST00000355327+118793_85101019.0DomainTSP type-1 4
HgeneTHSD4chr15:71839819chr14:100803538ENST00000355327+118852_91101019.0DomainTSP type-1 5
HgeneTHSD4chr15:71839819chr14:100803538ENST00000355327+118912_96801019.0DomainTSP type-1 6
HgeneTHSD4chr15:71839819chr14:100803538ENST00000355327+118971_100801019.0DomainPLAC
HgeneTHSD4chr15:71839820chr14:100803539ENST00000261862+11753_30701019.0DomainTSP type-1 1
HgeneTHSD4chr15:71839820chr14:100803539ENST00000261862+117676_73701019.0DomainTSP type-1 2
HgeneTHSD4chr15:71839820chr14:100803539ENST00000261862+117739_79201019.0DomainTSP type-1 3
HgeneTHSD4chr15:71839820chr14:100803539ENST00000261862+117793_85101019.0DomainTSP type-1 4
HgeneTHSD4chr15:71839820chr14:100803539ENST00000261862+117852_91101019.0DomainTSP type-1 5
HgeneTHSD4chr15:71839820chr14:100803539ENST00000261862+117912_96801019.0DomainTSP type-1 6
HgeneTHSD4chr15:71839820chr14:100803539ENST00000261862+117971_100801019.0DomainPLAC
HgeneTHSD4chr15:71839820chr14:100803539ENST00000355327+11853_30701019.0DomainTSP type-1 1
HgeneTHSD4chr15:71839820chr14:100803539ENST00000355327+118676_73701019.0DomainTSP type-1 2
HgeneTHSD4chr15:71839820chr14:100803539ENST00000355327+118739_79201019.0DomainTSP type-1 3
HgeneTHSD4chr15:71839820chr14:100803539ENST00000355327+118793_85101019.0DomainTSP type-1 4
HgeneTHSD4chr15:71839820chr14:100803539ENST00000355327+118852_91101019.0DomainTSP type-1 5
HgeneTHSD4chr15:71839820chr14:100803539ENST00000355327+118912_96801019.0DomainTSP type-1 6
HgeneTHSD4chr15:71839820chr14:100803539ENST00000355327+118971_100801019.0DomainPLAC
TgeneWARSchr15:71839819chr14:100803538ENST000003441027108_64330431.0DomainWHEP-TRS
TgeneWARSchr15:71839819chr14:100803538ENST000003553388118_64371472.0DomainWHEP-TRS
TgeneWARSchr15:71839819chr14:100803538ENST000003586557108_64330431.0DomainWHEP-TRS
TgeneWARSchr15:71839819chr14:100803538ENST000003928828118_64371472.0DomainWHEP-TRS
TgeneWARSchr15:71839819chr14:100803538ENST000005566458118_64330431.0DomainWHEP-TRS
TgeneWARSchr15:71839819chr14:100803538ENST000005571359128_64371472.0DomainWHEP-TRS
TgeneWARSchr15:71839820chr14:100803539ENST000003441027108_64330431.0DomainWHEP-TRS
TgeneWARSchr15:71839820chr14:100803539ENST000003553388118_64371472.0DomainWHEP-TRS
TgeneWARSchr15:71839820chr14:100803539ENST000003586557108_64330431.0DomainWHEP-TRS
TgeneWARSchr15:71839820chr14:100803539ENST000003928828118_64371472.0DomainWHEP-TRS
TgeneWARSchr15:71839820chr14:100803539ENST000005566458118_64330431.0DomainWHEP-TRS
TgeneWARSchr15:71839820chr14:100803539ENST000005571359128_64371472.0DomainWHEP-TRS
TgeneWARSchr15:71839819chr14:100803538ENST00000344102710164_173330431.0MotifNote='HIGH' region
TgeneWARSchr15:71839819chr14:100803538ENST00000355338811164_173371472.0MotifNote='HIGH' region
TgeneWARSchr15:71839819chr14:100803538ENST00000355338811349_353371472.0MotifNote='KMSKS' region
TgeneWARSchr15:71839819chr14:100803538ENST00000358655710164_173330431.0MotifNote='HIGH' region
TgeneWARSchr15:71839819chr14:100803538ENST00000392882811164_173371472.0MotifNote='HIGH' region
TgeneWARSchr15:71839819chr14:100803538ENST00000392882811349_353371472.0MotifNote='KMSKS' region
TgeneWARSchr15:71839819chr14:100803538ENST00000556645811164_173330431.0MotifNote='HIGH' region
TgeneWARSchr15:71839819chr14:100803538ENST00000557135912164_173371472.0MotifNote='HIGH' region
TgeneWARSchr15:71839819chr14:100803538ENST00000557135912349_353371472.0MotifNote='KMSKS' region
TgeneWARSchr15:71839820chr14:100803539ENST00000344102710164_173330431.0MotifNote='HIGH' region
TgeneWARSchr15:71839820chr14:100803539ENST00000355338811164_173371472.0MotifNote='HIGH' region
TgeneWARSchr15:71839820chr14:100803539ENST00000355338811349_353371472.0MotifNote='KMSKS' region
TgeneWARSchr15:71839820chr14:100803539ENST00000358655710164_173330431.0MotifNote='HIGH' region
TgeneWARSchr15:71839820chr14:100803539ENST00000392882811164_173371472.0MotifNote='HIGH' region
TgeneWARSchr15:71839820chr14:100803539ENST00000392882811349_353371472.0MotifNote='KMSKS' region
TgeneWARSchr15:71839820chr14:100803539ENST00000556645811164_173330431.0MotifNote='HIGH' region
TgeneWARSchr15:71839820chr14:100803539ENST00000557135912164_173371472.0MotifNote='HIGH' region
TgeneWARSchr15:71839820chr14:100803539ENST00000557135912349_353371472.0MotifNote='KMSKS' region


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Fusion Gene Sequence for THSD4-WARS


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>90781_90781_1_THSD4-WARS_THSD4_chr15_71839819_ENST00000357769_WARS_chr14_100803538_ENST00000344102_length(transcript)=1596nt_BP=246nt
AGAACAGAGGCTGAGCTCGAAGCGCCGGGCAGTACAGTGAGGGAGAGCCGAGGGAACCAGCGCGGTGCCTAGCGGAACTCCAGGGCTGGA
ATCCCGAGACACAAGTGCATCTGCTAGCTGTTAGCACTTGGCAGACGGAGTTCTCCTCTAGGGTAGTTCTAACTTTGGGTAATAATGTTT
GTCAGCTACCTGATATTAACATTGCTCCACGTTCAAACAGCAGTGTTAGCAAGACCTGGGGGAGAGGTCAATAAGCATGCGTTTTCTGGA
GGGAGAGACACCATCGAGGAGCACAGGCAGTTTGGGGGCAACTGTGATGTGGACGTGTCTTTCATGTACCTGACCTTCTTCCTCGAGGAC
GACGACAAGCTCGAGCAGATCAGGAAGGATTACACCAGCGGAGCCATGCTCACCGGTGAGCTCAAGAAGGCACTCATAGAGGTTCTGCAG
CCCTTGATCGCAGAGCACCAGGCCCGGCGCAAGGAGGTCACGGATGAGATAGTGAAAGAGTTCATGACTCCCCGGAAGCTGTCCTTCGAC
TTTCAGTAGCACTCGTTTTACATATGCTTATAAAAGAAGTGATGTATCAGTAATGTATCAATAATCCCAGCCCAGTCAAAGCACCGCCAC
CTGTAGGCTTCTGTCTCATGGTAATTACTGGGCCTGGCCTCTGTAAGCCTGTGTATGTTATCAATACTGTTTCTTCCTGTGAGTTCCATT
ATTTCTATCTCTTATGGGCAAAGCATTGTGGGTAATTGGTGCTGGCTAACATTGCATGGTCGGATAGAGAAGTCCAGCTGTGAGTCTCTC
CCCAAAGCAGCCCCACAGTGGAGCCTTTGGCTGGAAGTCCATGGGCCACCCTGTTCTTGTCCATGGAGGACTCCGAGGGTTCCAAGTATA
CTCTTAAGACCCACTCTGTTTAAAAATATATATTCTATGTATGCGTATATGGAATTGAAATGTCATTATTGTAACCTAGAAAGTGCTTTG
AAATATTGATGTGGGGAGGTTTATTGAGCACAAGATGTATTTCAGCCCATGCCCCCTCCCAAAAAGAAATTGATAAGTAAAAGCTTCGTT
ATACATTTGACTAAGAAATCACCCAGCTTTAAAGCTGCTTTTAACAATGAAGATTGAACAGAGTTCAGCAATTTTGATTAAATTAAGACT
TGGGGGTGAAACTTTCCAGTTTACTGAACTCCAGACCATGCATGTAGTCCACTCCAGAAATCATGCTCGCTTCCCTTGGCACACCAGTGT
TCTCCTGCCAAATGACCCTAGACCCTCTGTCCTGCAGAGTCAGGGTGGCTTTTCCCCTGACTGTGTCCGATGCCAAGGAGTCCTGGCCTC
CGCAGATGCTTCATTTTGACCCTTGGCTGCAGTGGAAGTCAGCACAGAGCAGTGCCCTGGCTGTGTCCCTGGACGGGTGGACTTAGCTAG
GGAGAAAGTCGAGGCAGCAGCCCTCGAGGCCCTCACAGATGTCTAGGCAGGCCTCATTTCATCACGCAGCATGTGCAGGCCTGGAAGAGC

>90781_90781_1_THSD4-WARS_THSD4_chr15_71839819_ENST00000357769_WARS_chr14_100803538_ENST00000344102_length(amino acids)=124AA_BP=17
MFVSYLILTLLHVQTAVLARPGGEVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEV

--------------------------------------------------------------
>90781_90781_2_THSD4-WARS_THSD4_chr15_71839819_ENST00000357769_WARS_chr14_100803538_ENST00000355338_length(transcript)=1606nt_BP=246nt
AGAACAGAGGCTGAGCTCGAAGCGCCGGGCAGTACAGTGAGGGAGAGCCGAGGGAACCAGCGCGGTGCCTAGCGGAACTCCAGGGCTGGA
ATCCCGAGACACAAGTGCATCTGCTAGCTGTTAGCACTTGGCAGACGGAGTTCTCCTCTAGGGTAGTTCTAACTTTGGGTAATAATGTTT
GTCAGCTACCTGATATTAACATTGCTCCACGTTCAAACAGCAGTGTTAGCAAGACCTGGGGGAGAGGTCAATAAGCATGCGTTTTCTGGA
GGGAGAGACACCATCGAGGAGCACAGGCAGTTTGGGGGCAACTGTGATGTGGACGTGTCTTTCATGTACCTGACCTTCTTCCTCGAGGAC
GACGACAAGCTCGAGCAGATCAGGAAGGATTACACCAGCGGAGCCATGCTCACCGGTGAGCTCAAGAAGGCACTCATAGAGGTTCTGCAG
CCCTTGATCGCAGAGCACCAGGCCCGGCGCAAGGAGGTCACGGATGAGATAGTGAAAGAGTTCATGACTCCCCGGAAGCTGTCCTTCGAC
TTTCAGTAGCACTCGTTTTACATATGCTTATAAAAGAAGTGATGTATCAGTAATGTATCAATAATCCCAGCCCAGTCAAAGCACCGCCAC
CTGTAGGCTTCTGTCTCATGGTAATTACTGGGCCTGGCCTCTGTAAGCCTGTGTATGTTATCAATACTGTTTCTTCCTGTGAGTTCCATT
ATTTCTATCTCTTATGGGCAAAGCATTGTGGGTAATTGGTGCTGGCTAACATTGCATGGTCGGATAGAGAAGTCCAGCTGTGAGTCTCTC
CCCAAAGCAGCCCCACAGTGGAGCCTTTGGCTGGAAGTCCATGGGCCACCCTGTTCTTGTCCATGGAGGACTCCGAGGGTTCCAAGTATA
CTCTTAAGACCCACTCTGTTTAAAAATATATATTCTATGTATGCGTATATGGAATTGAAATGTCATTATTGTAACCTAGAAAGTGCTTTG
AAATATTGATGTGGGGAGGTTTATTGAGCACAAGATGTATTTCAGCCCATGCCCCCTCCCAAAAAGAAATTGATAAGTAAAAGCTTCGTT
ATACATTTGACTAAGAAATCACCCAGCTTTAAAGCTGCTTTTAACAATGAAGATTGAACAGAGTTCAGCAATTTTGATTAAATTAAGACT
TGGGGGTGAAACTTTCCAGTTTACTGAACTCCAGACCATGCATGTAGTCCACTCCAGAAATCATGCTCGCTTCCCTTGGCACACCAGTGT
TCTCCTGCCAAATGACCCTAGACCCTCTGTCCTGCAGAGTCAGGGTGGCTTTTCCCCTGACTGTGTCCGATGCCAAGGAGTCCTGGCCTC
CGCAGATGCTTCATTTTGACCCTTGGCTGCAGTGGAAGTCAGCACAGAGCAGTGCCCTGGCTGTGTCCCTGGACGGGTGGACTTAGCTAG
GGAGAAAGTCGAGGCAGCAGCCCTCGAGGCCCTCACAGATGTCTAGGCAGGCCTCATTTCATCACGCAGCATGTGCAGGCCTGGAAGAGC

>90781_90781_2_THSD4-WARS_THSD4_chr15_71839819_ENST00000357769_WARS_chr14_100803538_ENST00000355338_length(amino acids)=124AA_BP=17
MFVSYLILTLLHVQTAVLARPGGEVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEV

--------------------------------------------------------------
>90781_90781_3_THSD4-WARS_THSD4_chr15_71839819_ENST00000357769_WARS_chr14_100803538_ENST00000358655_length(transcript)=1622nt_BP=246nt
AGAACAGAGGCTGAGCTCGAAGCGCCGGGCAGTACAGTGAGGGAGAGCCGAGGGAACCAGCGCGGTGCCTAGCGGAACTCCAGGGCTGGA
ATCCCGAGACACAAGTGCATCTGCTAGCTGTTAGCACTTGGCAGACGGAGTTCTCCTCTAGGGTAGTTCTAACTTTGGGTAATAATGTTT
GTCAGCTACCTGATATTAACATTGCTCCACGTTCAAACAGCAGTGTTAGCAAGACCTGGGGGAGAGGTCAATAAGCATGCGTTTTCTGGA
GGGAGAGACACCATCGAGGAGCACAGGCAGTTTGGGGGCAACTGTGATGTGGACGTGTCTTTCATGTACCTGACCTTCTTCCTCGAGGAC
GACGACAAGCTCGAGCAGATCAGGAAGGATTACACCAGCGGAGCCATGCTCACCGGTGAGCTCAAGAAGGCACTCATAGAGGTTCTGCAG
CCCTTGATCGCAGAGCACCAGGCCCGGCGCAAGGAGGTCACGGATGAGATAGTGAAAGAGTTCATGACTCCCCGGAAGCTGTCCTTCGAC
TTTCAGTAGCACTCGTTTTACATATGCTTATAAAAGAAGTGATGTATCAGTAATGTATCAATAATCCCAGCCCAGTCAAAGCACCGCCAC
CTGTAGGCTTCTGTCTCATGGTAATTACTGGGCCTGGCCTCTGTAAGCCTGTGTATGTTATCAATACTGTTTCTTCCTGTGAGTTCCATT
ATTTCTATCTCTTATGGGCAAAGCATTGTGGGTAATTGGTGCTGGCTAACATTGCATGGTCGGATAGAGAAGTCCAGCTGTGAGTCTCTC
CCCAAAGCAGCCCCACAGTGGAGCCTTTGGCTGGAAGTCCATGGGCCACCCTGTTCTTGTCCATGGAGGACTCCGAGGGTTCCAAGTATA
CTCTTAAGACCCACTCTGTTTAAAAATATATATTCTATGTATGCGTATATGGAATTGAAATGTCATTATTGTAACCTAGAAAGTGCTTTG
AAATATTGATGTGGGGAGGTTTATTGAGCACAAGATGTATTTCAGCCCATGCCCCCTCCCAAAAAGAAATTGATAAGTAAAAGCTTCGTT
ATACATTTGACTAAGAAATCACCCAGCTTTAAAGCTGCTTTTAACAATGAAGATTGAACAGAGTTCAGCAATTTTGATTAAATTAAGACT
TGGGGGTGAAACTTTCCAGTTTACTGAACTCCAGACCATGCATGTAGTCCACTCCAGAAATCATGCTCGCTTCCCTTGGCACACCAGTGT
TCTCCTGCCAAATGACCCTAGACCCTCTGTCCTGCAGAGTCAGGGTGGCTTTTCCCCTGACTGTGTCCGATGCCAAGGAGTCCTGGCCTC
CGCAGATGCTTCATTTTGACCCTTGGCTGCAGTGGAAGTCAGCACAGAGCAGTGCCCTGGCTGTGTCCCTGGACGGGTGGACTTAGCTAG
GGAGAAAGTCGAGGCAGCAGCCCTCGAGGCCCTCACAGATGTCTAGGCAGGCCTCATTTCATCACGCAGCATGTGCAGGCCTGGAAGAGC
AAAGCCAAATCTCAGGGAAGTCCTTGGTTGATGTATCTGGGTCTCCTCTGGAGCACTCTGCCCTCCTGTCACCCAGTAGAGTAAATAAAC

>90781_90781_3_THSD4-WARS_THSD4_chr15_71839819_ENST00000357769_WARS_chr14_100803538_ENST00000358655_length(amino acids)=124AA_BP=17
MFVSYLILTLLHVQTAVLARPGGEVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEV

--------------------------------------------------------------
>90781_90781_4_THSD4-WARS_THSD4_chr15_71839819_ENST00000357769_WARS_chr14_100803538_ENST00000392882_length(transcript)=1636nt_BP=246nt
AGAACAGAGGCTGAGCTCGAAGCGCCGGGCAGTACAGTGAGGGAGAGCCGAGGGAACCAGCGCGGTGCCTAGCGGAACTCCAGGGCTGGA
ATCCCGAGACACAAGTGCATCTGCTAGCTGTTAGCACTTGGCAGACGGAGTTCTCCTCTAGGGTAGTTCTAACTTTGGGTAATAATGTTT
GTCAGCTACCTGATATTAACATTGCTCCACGTTCAAACAGCAGTGTTAGCAAGACCTGGGGGAGAGGTCAATAAGCATGCGTTTTCTGGA
GGGAGAGACACCATCGAGGAGCACAGGCAGTTTGGGGGCAACTGTGATGTGGACGTGTCTTTCATGTACCTGACCTTCTTCCTCGAGGAC
GACGACAAGCTCGAGCAGATCAGGAAGGATTACACCAGCGGAGCCATGCTCACCGGTGAGCTCAAGAAGGCACTCATAGAGGTTCTGCAG
CCCTTGATCGCAGAGCACCAGGCCCGGCGCAAGGAGGTCACGGATGAGATAGTGAAAGAGTTCATGACTCCCCGGAAGCTGTCCTTCGAC
TTTCAGTAGCACTCGTTTTACATATGCTTATAAAAGAAGTGATGTATCAGTAATGTATCAATAATCCCAGCCCAGTCAAAGCACCGCCAC
CTGTAGGCTTCTGTCTCATGGTAATTACTGGGCCTGGCCTCTGTAAGCCTGTGTATGTTATCAATACTGTTTCTTCCTGTGAGTTCCATT
ATTTCTATCTCTTATGGGCAAAGCATTGTGGGTAATTGGTGCTGGCTAACATTGCATGGTCGGATAGAGAAGTCCAGCTGTGAGTCTCTC
CCCAAAGCAGCCCCACAGTGGAGCCTTTGGCTGGAAGTCCATGGGCCACCCTGTTCTTGTCCATGGAGGACTCCGAGGGTTCCAAGTATA
CTCTTAAGACCCACTCTGTTTAAAAATATATATTCTATGTATGCGTATATGGAATTGAAATGTCATTATTGTAACCTAGAAAGTGCTTTG
AAATATTGATGTGGGGAGGTTTATTGAGCACAAGATGTATTTCAGCCCATGCCCCCTCCCAAAAAGAAATTGATAAGTAAAAGCTTCGTT
ATACATTTGACTAAGAAATCACCCAGCTTTAAAGCTGCTTTTAACAATGAAGATTGAACAGAGTTCAGCAATTTTGATTAAATTAAGACT
TGGGGGTGAAACTTTCCAGTTTACTGAACTCCAGACCATGCATGTAGTCCACTCCAGAAATCATGCTCGCTTCCCTTGGCACACCAGTGT
TCTCCTGCCAAATGACCCTAGACCCTCTGTCCTGCAGAGTCAGGGTGGCTTTTCCCCTGACTGTGTCCGATGCCAAGGAGTCCTGGCCTC
CGCAGATGCTTCATTTTGACCCTTGGCTGCAGTGGAAGTCAGCACAGAGCAGTGCCCTGGCTGTGTCCCTGGACGGGTGGACTTAGCTAG
GGAGAAAGTCGAGGCAGCAGCCCTCGAGGCCCTCACAGATGTCTAGGCAGGCCTCATTTCATCACGCAGCATGTGCAGGCCTGGAAGAGC
AAAGCCAAATCTCAGGGAAGTCCTTGGTTGATGTATCTGGGTCTCCTCTGGAGCACTCTGCCCTCCTGTCACCCAGTAGAGTAAATAAAC

>90781_90781_4_THSD4-WARS_THSD4_chr15_71839819_ENST00000357769_WARS_chr14_100803538_ENST00000392882_length(amino acids)=124AA_BP=17
MFVSYLILTLLHVQTAVLARPGGEVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEV

--------------------------------------------------------------
>90781_90781_5_THSD4-WARS_THSD4_chr15_71839819_ENST00000357769_WARS_chr14_100803538_ENST00000556645_length(transcript)=931nt_BP=246nt
AGAACAGAGGCTGAGCTCGAAGCGCCGGGCAGTACAGTGAGGGAGAGCCGAGGGAACCAGCGCGGTGCCTAGCGGAACTCCAGGGCTGGA
ATCCCGAGACACAAGTGCATCTGCTAGCTGTTAGCACTTGGCAGACGGAGTTCTCCTCTAGGGTAGTTCTAACTTTGGGTAATAATGTTT
GTCAGCTACCTGATATTAACATTGCTCCACGTTCAAACAGCAGTGTTAGCAAGACCTGGGGGAGAGGTCAATAAGCATGCGTTTTCTGGA
GGGAGAGACACCATCGAGGAGCACAGGCAGTTTGGGGGCAACTGTGATGTGGACGTGTCTTTCATGTACCTGACCTTCTTCCTCGAGGAC
GACGACAAGCTCGAGCAGATCAGGAAGGATTACACCAGCGGAGCCATGCTCACCGGTGAGCTCAAGAAGGCACTCATAGAGGTTCTGCAG
CCCTTGATCGCAGAGCACCAGGCCCGGCGCAAGGAGGTCACGGATGAGATAGTGAAAGAGTTCATGACTCCCCGGAAGCTGTCCTTCGAC
TTTCAGTAGCACTCGTTTTACATATGCTTATAAAAGAAGTGATGTATCAGTAATGTATCAATAATCCCAGCCCAGTCAAAGCACCGCCAC
CTGTAGGCTTCTGTCTCATGGTAATTACTGGGCCTGGCCTCTGTAAGCCTGTGTATGTTATCAATACTGTTTCTTCCTGTGAGTTCCATT
ATTTCTATCTCTTATGGGCAAAGCATTGTGGGTAATTGGTGCTGGCTAACATTGCATGGTCGGATAGAGAAGTCCAGCTGTGAGTCTCTC
CCCAAAGCAGCCCCACAGTGGAGCCTTTGGCTGGAAGTCCATGGGCCACCCTGTTCTTGTCCATGGAGGACTCCGAGGGTTCCAAGTATA

>90781_90781_5_THSD4-WARS_THSD4_chr15_71839819_ENST00000357769_WARS_chr14_100803538_ENST00000556645_length(amino acids)=124AA_BP=17
MFVSYLILTLLHVQTAVLARPGGEVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEV

--------------------------------------------------------------
>90781_90781_6_THSD4-WARS_THSD4_chr15_71839819_ENST00000357769_WARS_chr14_100803538_ENST00000557135_length(transcript)=945nt_BP=246nt
AGAACAGAGGCTGAGCTCGAAGCGCCGGGCAGTACAGTGAGGGAGAGCCGAGGGAACCAGCGCGGTGCCTAGCGGAACTCCAGGGCTGGA
ATCCCGAGACACAAGTGCATCTGCTAGCTGTTAGCACTTGGCAGACGGAGTTCTCCTCTAGGGTAGTTCTAACTTTGGGTAATAATGTTT
GTCAGCTACCTGATATTAACATTGCTCCACGTTCAAACAGCAGTGTTAGCAAGACCTGGGGGAGAGGTCAATAAGCATGCGTTTTCTGGA
GGGAGAGACACCATCGAGGAGCACAGGCAGTTTGGGGGCAACTGTGATGTGGACGTGTCTTTCATGTACCTGACCTTCTTCCTCGAGGAC
GACGACAAGCTCGAGCAGATCAGGAAGGATTACACCAGCGGAGCCATGCTCACCGGTGAGCTCAAGAAGGCACTCATAGAGGTTCTGCAG
CCCTTGATCGCAGAGCACCAGGCCCGGCGCAAGGAGGTCACGGATGAGATAGTGAAAGAGTTCATGACTCCCCGGAAGCTGTCCTTCGAC
TTTCAGTAGCACTCGTTTTACATATGCTTATAAAAGAAGTGATGTATCAGTAATGTATCAATAATCCCAGCCCAGTCAAAGCACCGCCAC
CTGTAGGCTTCTGTCTCATGGTAATTACTGGGCCTGGCCTCTGTAAGCCTGTGTATGTTATCAATACTGTTTCTTCCTGTGAGTTCCATT
ATTTCTATCTCTTATGGGCAAAGCATTGTGGGTAATTGGTGCTGGCTAACATTGCATGGTCGGATAGAGAAGTCCAGCTGTGAGTCTCTC
CCCAAAGCAGCCCCACAGTGGAGCCTTTGGCTGGAAGTCCATGGGCCACCCTGTTCTTGTCCATGGAGGACTCCGAGGGTTCCAAGTATA

>90781_90781_6_THSD4-WARS_THSD4_chr15_71839819_ENST00000357769_WARS_chr14_100803538_ENST00000557135_length(amino acids)=124AA_BP=17
MFVSYLILTLLHVQTAVLARPGGEVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEV

--------------------------------------------------------------
>90781_90781_7_THSD4-WARS_THSD4_chr15_71839820_ENST00000357769_WARS_chr14_100803539_ENST00000344102_length(transcript)=1596nt_BP=246nt
AGAACAGAGGCTGAGCTCGAAGCGCCGGGCAGTACAGTGAGGGAGAGCCGAGGGAACCAGCGCGGTGCCTAGCGGAACTCCAGGGCTGGA
ATCCCGAGACACAAGTGCATCTGCTAGCTGTTAGCACTTGGCAGACGGAGTTCTCCTCTAGGGTAGTTCTAACTTTGGGTAATAATGTTT
GTCAGCTACCTGATATTAACATTGCTCCACGTTCAAACAGCAGTGTTAGCAAGACCTGGGGGAGAGGTCAATAAGCATGCGTTTTCTGGA
GGGAGAGACACCATCGAGGAGCACAGGCAGTTTGGGGGCAACTGTGATGTGGACGTGTCTTTCATGTACCTGACCTTCTTCCTCGAGGAC
GACGACAAGCTCGAGCAGATCAGGAAGGATTACACCAGCGGAGCCATGCTCACCGGTGAGCTCAAGAAGGCACTCATAGAGGTTCTGCAG
CCCTTGATCGCAGAGCACCAGGCCCGGCGCAAGGAGGTCACGGATGAGATAGTGAAAGAGTTCATGACTCCCCGGAAGCTGTCCTTCGAC
TTTCAGTAGCACTCGTTTTACATATGCTTATAAAAGAAGTGATGTATCAGTAATGTATCAATAATCCCAGCCCAGTCAAAGCACCGCCAC
CTGTAGGCTTCTGTCTCATGGTAATTACTGGGCCTGGCCTCTGTAAGCCTGTGTATGTTATCAATACTGTTTCTTCCTGTGAGTTCCATT
ATTTCTATCTCTTATGGGCAAAGCATTGTGGGTAATTGGTGCTGGCTAACATTGCATGGTCGGATAGAGAAGTCCAGCTGTGAGTCTCTC
CCCAAAGCAGCCCCACAGTGGAGCCTTTGGCTGGAAGTCCATGGGCCACCCTGTTCTTGTCCATGGAGGACTCCGAGGGTTCCAAGTATA
CTCTTAAGACCCACTCTGTTTAAAAATATATATTCTATGTATGCGTATATGGAATTGAAATGTCATTATTGTAACCTAGAAAGTGCTTTG
AAATATTGATGTGGGGAGGTTTATTGAGCACAAGATGTATTTCAGCCCATGCCCCCTCCCAAAAAGAAATTGATAAGTAAAAGCTTCGTT
ATACATTTGACTAAGAAATCACCCAGCTTTAAAGCTGCTTTTAACAATGAAGATTGAACAGAGTTCAGCAATTTTGATTAAATTAAGACT
TGGGGGTGAAACTTTCCAGTTTACTGAACTCCAGACCATGCATGTAGTCCACTCCAGAAATCATGCTCGCTTCCCTTGGCACACCAGTGT
TCTCCTGCCAAATGACCCTAGACCCTCTGTCCTGCAGAGTCAGGGTGGCTTTTCCCCTGACTGTGTCCGATGCCAAGGAGTCCTGGCCTC
CGCAGATGCTTCATTTTGACCCTTGGCTGCAGTGGAAGTCAGCACAGAGCAGTGCCCTGGCTGTGTCCCTGGACGGGTGGACTTAGCTAG
GGAGAAAGTCGAGGCAGCAGCCCTCGAGGCCCTCACAGATGTCTAGGCAGGCCTCATTTCATCACGCAGCATGTGCAGGCCTGGAAGAGC

>90781_90781_7_THSD4-WARS_THSD4_chr15_71839820_ENST00000357769_WARS_chr14_100803539_ENST00000344102_length(amino acids)=124AA_BP=17
MFVSYLILTLLHVQTAVLARPGGEVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEV

--------------------------------------------------------------
>90781_90781_8_THSD4-WARS_THSD4_chr15_71839820_ENST00000357769_WARS_chr14_100803539_ENST00000355338_length(transcript)=1606nt_BP=246nt
AGAACAGAGGCTGAGCTCGAAGCGCCGGGCAGTACAGTGAGGGAGAGCCGAGGGAACCAGCGCGGTGCCTAGCGGAACTCCAGGGCTGGA
ATCCCGAGACACAAGTGCATCTGCTAGCTGTTAGCACTTGGCAGACGGAGTTCTCCTCTAGGGTAGTTCTAACTTTGGGTAATAATGTTT
GTCAGCTACCTGATATTAACATTGCTCCACGTTCAAACAGCAGTGTTAGCAAGACCTGGGGGAGAGGTCAATAAGCATGCGTTTTCTGGA
GGGAGAGACACCATCGAGGAGCACAGGCAGTTTGGGGGCAACTGTGATGTGGACGTGTCTTTCATGTACCTGACCTTCTTCCTCGAGGAC
GACGACAAGCTCGAGCAGATCAGGAAGGATTACACCAGCGGAGCCATGCTCACCGGTGAGCTCAAGAAGGCACTCATAGAGGTTCTGCAG
CCCTTGATCGCAGAGCACCAGGCCCGGCGCAAGGAGGTCACGGATGAGATAGTGAAAGAGTTCATGACTCCCCGGAAGCTGTCCTTCGAC
TTTCAGTAGCACTCGTTTTACATATGCTTATAAAAGAAGTGATGTATCAGTAATGTATCAATAATCCCAGCCCAGTCAAAGCACCGCCAC
CTGTAGGCTTCTGTCTCATGGTAATTACTGGGCCTGGCCTCTGTAAGCCTGTGTATGTTATCAATACTGTTTCTTCCTGTGAGTTCCATT
ATTTCTATCTCTTATGGGCAAAGCATTGTGGGTAATTGGTGCTGGCTAACATTGCATGGTCGGATAGAGAAGTCCAGCTGTGAGTCTCTC
CCCAAAGCAGCCCCACAGTGGAGCCTTTGGCTGGAAGTCCATGGGCCACCCTGTTCTTGTCCATGGAGGACTCCGAGGGTTCCAAGTATA
CTCTTAAGACCCACTCTGTTTAAAAATATATATTCTATGTATGCGTATATGGAATTGAAATGTCATTATTGTAACCTAGAAAGTGCTTTG
AAATATTGATGTGGGGAGGTTTATTGAGCACAAGATGTATTTCAGCCCATGCCCCCTCCCAAAAAGAAATTGATAAGTAAAAGCTTCGTT
ATACATTTGACTAAGAAATCACCCAGCTTTAAAGCTGCTTTTAACAATGAAGATTGAACAGAGTTCAGCAATTTTGATTAAATTAAGACT
TGGGGGTGAAACTTTCCAGTTTACTGAACTCCAGACCATGCATGTAGTCCACTCCAGAAATCATGCTCGCTTCCCTTGGCACACCAGTGT
TCTCCTGCCAAATGACCCTAGACCCTCTGTCCTGCAGAGTCAGGGTGGCTTTTCCCCTGACTGTGTCCGATGCCAAGGAGTCCTGGCCTC
CGCAGATGCTTCATTTTGACCCTTGGCTGCAGTGGAAGTCAGCACAGAGCAGTGCCCTGGCTGTGTCCCTGGACGGGTGGACTTAGCTAG
GGAGAAAGTCGAGGCAGCAGCCCTCGAGGCCCTCACAGATGTCTAGGCAGGCCTCATTTCATCACGCAGCATGTGCAGGCCTGGAAGAGC

>90781_90781_8_THSD4-WARS_THSD4_chr15_71839820_ENST00000357769_WARS_chr14_100803539_ENST00000355338_length(amino acids)=124AA_BP=17
MFVSYLILTLLHVQTAVLARPGGEVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEV

--------------------------------------------------------------
>90781_90781_9_THSD4-WARS_THSD4_chr15_71839820_ENST00000357769_WARS_chr14_100803539_ENST00000358655_length(transcript)=1622nt_BP=246nt
AGAACAGAGGCTGAGCTCGAAGCGCCGGGCAGTACAGTGAGGGAGAGCCGAGGGAACCAGCGCGGTGCCTAGCGGAACTCCAGGGCTGGA
ATCCCGAGACACAAGTGCATCTGCTAGCTGTTAGCACTTGGCAGACGGAGTTCTCCTCTAGGGTAGTTCTAACTTTGGGTAATAATGTTT
GTCAGCTACCTGATATTAACATTGCTCCACGTTCAAACAGCAGTGTTAGCAAGACCTGGGGGAGAGGTCAATAAGCATGCGTTTTCTGGA
GGGAGAGACACCATCGAGGAGCACAGGCAGTTTGGGGGCAACTGTGATGTGGACGTGTCTTTCATGTACCTGACCTTCTTCCTCGAGGAC
GACGACAAGCTCGAGCAGATCAGGAAGGATTACACCAGCGGAGCCATGCTCACCGGTGAGCTCAAGAAGGCACTCATAGAGGTTCTGCAG
CCCTTGATCGCAGAGCACCAGGCCCGGCGCAAGGAGGTCACGGATGAGATAGTGAAAGAGTTCATGACTCCCCGGAAGCTGTCCTTCGAC
TTTCAGTAGCACTCGTTTTACATATGCTTATAAAAGAAGTGATGTATCAGTAATGTATCAATAATCCCAGCCCAGTCAAAGCACCGCCAC
CTGTAGGCTTCTGTCTCATGGTAATTACTGGGCCTGGCCTCTGTAAGCCTGTGTATGTTATCAATACTGTTTCTTCCTGTGAGTTCCATT
ATTTCTATCTCTTATGGGCAAAGCATTGTGGGTAATTGGTGCTGGCTAACATTGCATGGTCGGATAGAGAAGTCCAGCTGTGAGTCTCTC
CCCAAAGCAGCCCCACAGTGGAGCCTTTGGCTGGAAGTCCATGGGCCACCCTGTTCTTGTCCATGGAGGACTCCGAGGGTTCCAAGTATA
CTCTTAAGACCCACTCTGTTTAAAAATATATATTCTATGTATGCGTATATGGAATTGAAATGTCATTATTGTAACCTAGAAAGTGCTTTG
AAATATTGATGTGGGGAGGTTTATTGAGCACAAGATGTATTTCAGCCCATGCCCCCTCCCAAAAAGAAATTGATAAGTAAAAGCTTCGTT
ATACATTTGACTAAGAAATCACCCAGCTTTAAAGCTGCTTTTAACAATGAAGATTGAACAGAGTTCAGCAATTTTGATTAAATTAAGACT
TGGGGGTGAAACTTTCCAGTTTACTGAACTCCAGACCATGCATGTAGTCCACTCCAGAAATCATGCTCGCTTCCCTTGGCACACCAGTGT
TCTCCTGCCAAATGACCCTAGACCCTCTGTCCTGCAGAGTCAGGGTGGCTTTTCCCCTGACTGTGTCCGATGCCAAGGAGTCCTGGCCTC
CGCAGATGCTTCATTTTGACCCTTGGCTGCAGTGGAAGTCAGCACAGAGCAGTGCCCTGGCTGTGTCCCTGGACGGGTGGACTTAGCTAG
GGAGAAAGTCGAGGCAGCAGCCCTCGAGGCCCTCACAGATGTCTAGGCAGGCCTCATTTCATCACGCAGCATGTGCAGGCCTGGAAGAGC
AAAGCCAAATCTCAGGGAAGTCCTTGGTTGATGTATCTGGGTCTCCTCTGGAGCACTCTGCCCTCCTGTCACCCAGTAGAGTAAATAAAC

>90781_90781_9_THSD4-WARS_THSD4_chr15_71839820_ENST00000357769_WARS_chr14_100803539_ENST00000358655_length(amino acids)=124AA_BP=17
MFVSYLILTLLHVQTAVLARPGGEVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEV

--------------------------------------------------------------
>90781_90781_10_THSD4-WARS_THSD4_chr15_71839820_ENST00000357769_WARS_chr14_100803539_ENST00000392882_length(transcript)=1636nt_BP=246nt
AGAACAGAGGCTGAGCTCGAAGCGCCGGGCAGTACAGTGAGGGAGAGCCGAGGGAACCAGCGCGGTGCCTAGCGGAACTCCAGGGCTGGA
ATCCCGAGACACAAGTGCATCTGCTAGCTGTTAGCACTTGGCAGACGGAGTTCTCCTCTAGGGTAGTTCTAACTTTGGGTAATAATGTTT
GTCAGCTACCTGATATTAACATTGCTCCACGTTCAAACAGCAGTGTTAGCAAGACCTGGGGGAGAGGTCAATAAGCATGCGTTTTCTGGA
GGGAGAGACACCATCGAGGAGCACAGGCAGTTTGGGGGCAACTGTGATGTGGACGTGTCTTTCATGTACCTGACCTTCTTCCTCGAGGAC
GACGACAAGCTCGAGCAGATCAGGAAGGATTACACCAGCGGAGCCATGCTCACCGGTGAGCTCAAGAAGGCACTCATAGAGGTTCTGCAG
CCCTTGATCGCAGAGCACCAGGCCCGGCGCAAGGAGGTCACGGATGAGATAGTGAAAGAGTTCATGACTCCCCGGAAGCTGTCCTTCGAC
TTTCAGTAGCACTCGTTTTACATATGCTTATAAAAGAAGTGATGTATCAGTAATGTATCAATAATCCCAGCCCAGTCAAAGCACCGCCAC
CTGTAGGCTTCTGTCTCATGGTAATTACTGGGCCTGGCCTCTGTAAGCCTGTGTATGTTATCAATACTGTTTCTTCCTGTGAGTTCCATT
ATTTCTATCTCTTATGGGCAAAGCATTGTGGGTAATTGGTGCTGGCTAACATTGCATGGTCGGATAGAGAAGTCCAGCTGTGAGTCTCTC
CCCAAAGCAGCCCCACAGTGGAGCCTTTGGCTGGAAGTCCATGGGCCACCCTGTTCTTGTCCATGGAGGACTCCGAGGGTTCCAAGTATA
CTCTTAAGACCCACTCTGTTTAAAAATATATATTCTATGTATGCGTATATGGAATTGAAATGTCATTATTGTAACCTAGAAAGTGCTTTG
AAATATTGATGTGGGGAGGTTTATTGAGCACAAGATGTATTTCAGCCCATGCCCCCTCCCAAAAAGAAATTGATAAGTAAAAGCTTCGTT
ATACATTTGACTAAGAAATCACCCAGCTTTAAAGCTGCTTTTAACAATGAAGATTGAACAGAGTTCAGCAATTTTGATTAAATTAAGACT
TGGGGGTGAAACTTTCCAGTTTACTGAACTCCAGACCATGCATGTAGTCCACTCCAGAAATCATGCTCGCTTCCCTTGGCACACCAGTGT
TCTCCTGCCAAATGACCCTAGACCCTCTGTCCTGCAGAGTCAGGGTGGCTTTTCCCCTGACTGTGTCCGATGCCAAGGAGTCCTGGCCTC
CGCAGATGCTTCATTTTGACCCTTGGCTGCAGTGGAAGTCAGCACAGAGCAGTGCCCTGGCTGTGTCCCTGGACGGGTGGACTTAGCTAG
GGAGAAAGTCGAGGCAGCAGCCCTCGAGGCCCTCACAGATGTCTAGGCAGGCCTCATTTCATCACGCAGCATGTGCAGGCCTGGAAGAGC
AAAGCCAAATCTCAGGGAAGTCCTTGGTTGATGTATCTGGGTCTCCTCTGGAGCACTCTGCCCTCCTGTCACCCAGTAGAGTAAATAAAC

>90781_90781_10_THSD4-WARS_THSD4_chr15_71839820_ENST00000357769_WARS_chr14_100803539_ENST00000392882_length(amino acids)=124AA_BP=17
MFVSYLILTLLHVQTAVLARPGGEVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEV

--------------------------------------------------------------
>90781_90781_11_THSD4-WARS_THSD4_chr15_71839820_ENST00000357769_WARS_chr14_100803539_ENST00000556645_length(transcript)=931nt_BP=246nt
AGAACAGAGGCTGAGCTCGAAGCGCCGGGCAGTACAGTGAGGGAGAGCCGAGGGAACCAGCGCGGTGCCTAGCGGAACTCCAGGGCTGGA
ATCCCGAGACACAAGTGCATCTGCTAGCTGTTAGCACTTGGCAGACGGAGTTCTCCTCTAGGGTAGTTCTAACTTTGGGTAATAATGTTT
GTCAGCTACCTGATATTAACATTGCTCCACGTTCAAACAGCAGTGTTAGCAAGACCTGGGGGAGAGGTCAATAAGCATGCGTTTTCTGGA
GGGAGAGACACCATCGAGGAGCACAGGCAGTTTGGGGGCAACTGTGATGTGGACGTGTCTTTCATGTACCTGACCTTCTTCCTCGAGGAC
GACGACAAGCTCGAGCAGATCAGGAAGGATTACACCAGCGGAGCCATGCTCACCGGTGAGCTCAAGAAGGCACTCATAGAGGTTCTGCAG
CCCTTGATCGCAGAGCACCAGGCCCGGCGCAAGGAGGTCACGGATGAGATAGTGAAAGAGTTCATGACTCCCCGGAAGCTGTCCTTCGAC
TTTCAGTAGCACTCGTTTTACATATGCTTATAAAAGAAGTGATGTATCAGTAATGTATCAATAATCCCAGCCCAGTCAAAGCACCGCCAC
CTGTAGGCTTCTGTCTCATGGTAATTACTGGGCCTGGCCTCTGTAAGCCTGTGTATGTTATCAATACTGTTTCTTCCTGTGAGTTCCATT
ATTTCTATCTCTTATGGGCAAAGCATTGTGGGTAATTGGTGCTGGCTAACATTGCATGGTCGGATAGAGAAGTCCAGCTGTGAGTCTCTC
CCCAAAGCAGCCCCACAGTGGAGCCTTTGGCTGGAAGTCCATGGGCCACCCTGTTCTTGTCCATGGAGGACTCCGAGGGTTCCAAGTATA

>90781_90781_11_THSD4-WARS_THSD4_chr15_71839820_ENST00000357769_WARS_chr14_100803539_ENST00000556645_length(amino acids)=124AA_BP=17
MFVSYLILTLLHVQTAVLARPGGEVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEV

--------------------------------------------------------------
>90781_90781_12_THSD4-WARS_THSD4_chr15_71839820_ENST00000357769_WARS_chr14_100803539_ENST00000557135_length(transcript)=945nt_BP=246nt
AGAACAGAGGCTGAGCTCGAAGCGCCGGGCAGTACAGTGAGGGAGAGCCGAGGGAACCAGCGCGGTGCCTAGCGGAACTCCAGGGCTGGA
ATCCCGAGACACAAGTGCATCTGCTAGCTGTTAGCACTTGGCAGACGGAGTTCTCCTCTAGGGTAGTTCTAACTTTGGGTAATAATGTTT
GTCAGCTACCTGATATTAACATTGCTCCACGTTCAAACAGCAGTGTTAGCAAGACCTGGGGGAGAGGTCAATAAGCATGCGTTTTCTGGA
GGGAGAGACACCATCGAGGAGCACAGGCAGTTTGGGGGCAACTGTGATGTGGACGTGTCTTTCATGTACCTGACCTTCTTCCTCGAGGAC
GACGACAAGCTCGAGCAGATCAGGAAGGATTACACCAGCGGAGCCATGCTCACCGGTGAGCTCAAGAAGGCACTCATAGAGGTTCTGCAG
CCCTTGATCGCAGAGCACCAGGCCCGGCGCAAGGAGGTCACGGATGAGATAGTGAAAGAGTTCATGACTCCCCGGAAGCTGTCCTTCGAC
TTTCAGTAGCACTCGTTTTACATATGCTTATAAAAGAAGTGATGTATCAGTAATGTATCAATAATCCCAGCCCAGTCAAAGCACCGCCAC
CTGTAGGCTTCTGTCTCATGGTAATTACTGGGCCTGGCCTCTGTAAGCCTGTGTATGTTATCAATACTGTTTCTTCCTGTGAGTTCCATT
ATTTCTATCTCTTATGGGCAAAGCATTGTGGGTAATTGGTGCTGGCTAACATTGCATGGTCGGATAGAGAAGTCCAGCTGTGAGTCTCTC
CCCAAAGCAGCCCCACAGTGGAGCCTTTGGCTGGAAGTCCATGGGCCACCCTGTTCTTGTCCATGGAGGACTCCGAGGGTTCCAAGTATA

>90781_90781_12_THSD4-WARS_THSD4_chr15_71839820_ENST00000357769_WARS_chr14_100803539_ENST00000557135_length(amino acids)=124AA_BP=17
MFVSYLILTLLHVQTAVLARPGGEVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for THSD4-WARS


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for THSD4-WARS


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for THSD4-WARS


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource