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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TIMM23-PRKG1 (FusionGDB2 ID:90945)

Fusion Gene Summary for TIMM23-PRKG1

check button Fusion gene summary
Fusion gene informationFusion gene name: TIMM23-PRKG1
Fusion gene ID: 90945
HgeneTgene
Gene symbol

TIMM23

PRKG1

Gene ID

100287932

5592

Gene nametranslocase of inner mitochondrial membrane 23protein kinase cGMP-dependent 1
SynonymsTIM23AAT8|PKG|PKG1|PRKG1B|PRKGR1B|cGK|cGK 1|cGK1|cGKI|cGKI-BETA|cGKI-alpha
Cytomap

10q11.22

10q11.23-q21.1

Type of geneprotein-codingprotein-coding
Descriptionmitochondrial import inner membrane translocase subunit Tim23translocase of inner mitochondrial membrane 23 homologtranslocase of the inner mitochondrial membranecGMP-dependent protein kinase 1protein kinase, cGMP-dependent, regulatory, type I, betaprotein kinase, cGMP-dependent, type I
Modification date2020032920200322
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000260867, ENST00000374064, 
ENST00000374065, ENST00000485812, 
ENST00000373975, ENST00000373980, 
ENST00000373985, ENST00000401604, 
Fusion gene scores* DoF score7 X 5 X 5=17514 X 13 X 6=1092
# samples 714
** MAII scorelog2(7/175*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/1092*10)=-2.96347412397489
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TIMM23 [Title/Abstract] AND PRKG1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTIMM23(51606988)-PRKG1(53564345), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePRKG1

GO:0006468

protein phosphorylation

15905169

TgenePRKG1

GO:1904706

negative regulation of vascular smooth muscle cell proliferation

25447536

TgenePRKG1

GO:1904753

negative regulation of vascular associated smooth muscle cell migration

25447536


check buttonFusion gene breakpoints across TIMM23 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PRKG1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-E1-5304-01ATIMM23chr10

51606988

+PRKG1chr10

53564345

+
ChimerDB4LGGTCGA-E1-5304TIMM23chr10

51606988

-PRKG1chr10

53564345

+


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Fusion Gene ORF analysis for TIMM23-PRKG1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000260867ENST00000373975TIMM23chr10

51606988

+PRKG1chr10

53564345

+
5CDS-intronENST00000374064ENST00000373975TIMM23chr10

51606988

+PRKG1chr10

53564345

+
5CDS-intronENST00000374065ENST00000373975TIMM23chr10

51606988

+PRKG1chr10

53564345

+
In-frameENST00000260867ENST00000373980TIMM23chr10

51606988

+PRKG1chr10

53564345

+
In-frameENST00000260867ENST00000373985TIMM23chr10

51606988

+PRKG1chr10

53564345

+
In-frameENST00000260867ENST00000401604TIMM23chr10

51606988

+PRKG1chr10

53564345

+
In-frameENST00000374064ENST00000373980TIMM23chr10

51606988

+PRKG1chr10

53564345

+
In-frameENST00000374064ENST00000373985TIMM23chr10

51606988

+PRKG1chr10

53564345

+
In-frameENST00000374064ENST00000401604TIMM23chr10

51606988

+PRKG1chr10

53564345

+
In-frameENST00000374065ENST00000373980TIMM23chr10

51606988

+PRKG1chr10

53564345

+
In-frameENST00000374065ENST00000373985TIMM23chr10

51606988

+PRKG1chr10

53564345

+
In-frameENST00000374065ENST00000401604TIMM23chr10

51606988

+PRKG1chr10

53564345

+
intron-3CDSENST00000485812ENST00000373980TIMM23chr10

51606988

+PRKG1chr10

53564345

+
intron-3CDSENST00000485812ENST00000373985TIMM23chr10

51606988

+PRKG1chr10

53564345

+
intron-3CDSENST00000485812ENST00000401604TIMM23chr10

51606988

+PRKG1chr10

53564345

+
intron-intronENST00000485812ENST00000373975TIMM23chr10

51606988

+PRKG1chr10

53564345

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000260867TIMM23chr1051606988+ENST00000401604PRKG1chr1053564345+37216381242106660
ENST00000260867TIMM23chr1051606988+ENST00000373985PRKG1chr1053564345+65576381242106660
ENST00000260867TIMM23chr1051606988+ENST00000373980PRKG1chr1053564345+65576381242106660
ENST00000374064TIMM23chr1051606988+ENST00000401604PRKG1chr1053564345+35754921221960612
ENST00000374064TIMM23chr1051606988+ENST00000373985PRKG1chr1053564345+64114921221960612
ENST00000374064TIMM23chr1051606988+ENST00000373980PRKG1chr1053564345+64114921221960612
ENST00000374065TIMM23chr1051606988+ENST00000401604PRKG1chr1053564345+35915081051976623
ENST00000374065TIMM23chr1051606988+ENST00000373985PRKG1chr1053564345+64275081051976623
ENST00000374065TIMM23chr1051606988+ENST00000373980PRKG1chr1053564345+64275081051976623

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000260867ENST00000401604TIMM23chr1051606988+PRKG1chr1053564345+0.0008429030.9991571
ENST00000260867ENST00000373985TIMM23chr1051606988+PRKG1chr1053564345+0.0003155740.99968445
ENST00000260867ENST00000373980TIMM23chr1051606988+PRKG1chr1053564345+0.0003155740.99968445
ENST00000374064ENST00000401604TIMM23chr1051606988+PRKG1chr1053564345+0.0005260220.999474
ENST00000374064ENST00000373985TIMM23chr1051606988+PRKG1chr1053564345+0.0002007950.9997992
ENST00000374064ENST00000373980TIMM23chr1051606988+PRKG1chr1053564345+0.0002007950.9997992
ENST00000374065ENST00000401604TIMM23chr1051606988+PRKG1chr1053564345+0.0006397340.99936026
ENST00000374065ENST00000373985TIMM23chr1051606988+PRKG1chr1053564345+0.0002456190.99975437
ENST00000374065ENST00000373980TIMM23chr1051606988+PRKG1chr1053564345+0.0002456190.99975437

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Fusion Genomic Features for TIMM23-PRKG1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TIMM23chr1051606987-PRKG1chr1053564344+4.32E-050.99995685
TIMM23chr1051606987-PRKG1chr1053564344+4.32E-050.99995685

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for TIMM23-PRKG1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:51606988/chr10:53564345)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTIMM23chr10:51606988chr10:53564345ENST00000260867+67125_145171210.0TransmembraneHelical
HgeneTIMM23chr10:51606988chr10:53564345ENST00000260867+6773_93171210.0TransmembraneHelical
TgenePRKG1chr10:51606988chr10:53564345ENST00000373980218360_619197687.0DomainProtein kinase
TgenePRKG1chr10:51606988chr10:53564345ENST00000373980218620_671197687.0DomainAGC-kinase C-terminal
TgenePRKG1chr10:51606988chr10:53564345ENST00000401604218360_619182672.0DomainProtein kinase
TgenePRKG1chr10:51606988chr10:53564345ENST00000401604218620_671182672.0DomainAGC-kinase C-terminal
TgenePRKG1chr10:51606988chr10:53564345ENST00000373980218291_294197687.0Nucleotide binding3'%2C5'-cGMP 2
TgenePRKG1chr10:51606988chr10:53564345ENST00000373980218301_302197687.0Nucleotide binding3'%2C5'-cGMP 2
TgenePRKG1chr10:51606988chr10:53564345ENST00000373980218366_374197687.0Nucleotide bindingATP
TgenePRKG1chr10:51606988chr10:53564345ENST00000401604218291_294182672.0Nucleotide binding3'%2C5'-cGMP 2
TgenePRKG1chr10:51606988chr10:53564345ENST00000401604218301_302182672.0Nucleotide binding3'%2C5'-cGMP 2
TgenePRKG1chr10:51606988chr10:53564345ENST00000401604218366_374182672.0Nucleotide bindingATP
TgenePRKG1chr10:51606988chr10:53564345ENST00000373980218221_341197687.0RegionNote=cGMP-binding%2C low affinity
TgenePRKG1chr10:51606988chr10:53564345ENST00000401604218221_341182672.0RegionNote=cGMP-binding%2C low affinity

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTIMM23chr10:51606988chr10:53564345ENST00000260867+67181_197171210.0TransmembraneHelical
TgenePRKG1chr10:51606988chr10:53564345ENST000003739802182_59197687.0Coiled coilOntology_term=ECO:0000269
TgenePRKG1chr10:51606988chr10:53564345ENST000004016042182_59182672.0Coiled coilOntology_term=ECO:0000269
TgenePRKG1chr10:51606988chr10:53564345ENST00000373980218167_170197687.0Nucleotide binding3'%2C5'-cGMP 1
TgenePRKG1chr10:51606988chr10:53564345ENST00000373980218177_178197687.0Nucleotide binding3'%2C5'-cGMP 1
TgenePRKG1chr10:51606988chr10:53564345ENST00000401604218167_170182672.0Nucleotide binding3'%2C5'-cGMP 1
TgenePRKG1chr10:51606988chr10:53564345ENST00000401604218177_178182672.0Nucleotide binding3'%2C5'-cGMP 1
TgenePRKG1chr10:51606988chr10:53564345ENST00000373980218103_220197687.0RegionNote=cGMP-binding%2C high affinity
TgenePRKG1chr10:51606988chr10:53564345ENST000003739802182_102197687.0RegionNote=Required for dimerization
TgenePRKG1chr10:51606988chr10:53564345ENST0000037398021850_75197687.0RegionAutoinhibitory domain
TgenePRKG1chr10:51606988chr10:53564345ENST000003739802189_44197687.0RegionNote=Leucine-zipper
TgenePRKG1chr10:51606988chr10:53564345ENST00000401604218103_220182672.0RegionNote=cGMP-binding%2C high affinity
TgenePRKG1chr10:51606988chr10:53564345ENST000004016042182_102182672.0RegionNote=Required for dimerization
TgenePRKG1chr10:51606988chr10:53564345ENST0000040160421850_75182672.0RegionAutoinhibitory domain
TgenePRKG1chr10:51606988chr10:53564345ENST000004016042189_44182672.0RegionNote=Leucine-zipper


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Fusion Gene Sequence for TIMM23-PRKG1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>90945_90945_1_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000260867_PRKG1_chr10_53564345_ENST00000373980_length(transcript)=6557nt_BP=638nt
GAAGGTCAGCGTGTGAAGTAGGCGCTGGCAACGCGGGGTTACCCGCTGTTATTGAGGAGTAACGGCCCAGCGGACCACCCAGGCTTGAGG
CAGCGGCGGGAACCACTCGGTTTGCTGCGATACCATGGAAGGAGGCGGGGGAAGCGGCAACAAAACCACAGGGGGATTGGCCGGCTTTTT
CGGAGCCGGCGGAGCAGGTTACTCGCACGCGGATTTGGCTGGCGTCCCGCTAACTGGTATGAACCCTCTGTCTCCTTATTTAAATGTGGA
TCCACGATACCTCGTGCAGGATACAGATGAGTTTATTTTACCTACCGGAGCTAATAAAACCCGGGGCAGATTTGAGCTGGCCTTCTTTAC
GATTGGAGGATGTTGCATGACAGGGGCTGCGTTTGGTGCAATGAATGGTCTTCGGCTAGGATTGAAGGAAACCCAGAACATGGCCTGGTC
CAAACCAAGAAATGTACAGATTTTGAATATGGTGACTAGGCAAGGGGCACTTTGGGCTAATACTCTAGGTTCTCTGGCTTTGCTCTATAG
TGCATTTGGTGTCATCATTGAGAAAACACGAGGTGCAGAAGATGACCTTAACACAGTAGCAGCTGGAACCATGACAGGCATGTTGTATAA
ATGTACAGCTCTTGTAAATGTAAAACTCTGGGCCATTGATCGACAATGTTTTCAAACAATAATGATGAGGACAGGACTCATCAAGCATAC
CGAGTATATGGAATTTTTAAAAAGCGTTCCAACATTCCAGAGCCTTCCTGAAGAGATCCTCAGCAAGCTTGCTGATGTCCTTGAAGAGAC
CCACTATGAAAATGGAGAATATATTATCAGGCAAGGTGCAAGAGGGGACACCTTCTTTATCATCAGCAAAGGAACGGTAAATGTCACTCG
TGAAGACTCACCGAGTGAAGACCCAGTCTTTCTTAGAACTTTAGGAAAAGGAGACTGGTTTGGAGAGAAAGCCTTGCAGGGGGAAGATGT
GAGAACAGCAAACGTAATTGCTGCAGAAGCTGTAACCTGCCTTGTGATTGACAGAGACTCTTTTAAACATTTGATTGGAGGGCTGGATGA
TGTTTCTAATAAAGCATATGAAGATGCAGAAGCTAAAGCAAAATATGAAGCTGAAGCGGCTTTCTTCGCCAACCTGAAGCTGTCTGATTT
CAACATCATTGATACCCTTGGAGTTGGAGGTTTCGGACGAGTAGAACTGGTCCAGTTGAAAAGTGAAGAATCCAAAACGTTTGCAATGAA
GATTCTCAAGAAACGTCACATTGTGGACACAAGACAGCAGGAGCACATCCGCTCAGAGAAGCAGATCATGCAGGGGGCTCATTCCGATTT
CATAGTGAGACTGTACAGAACATTTAAGGACAGCAAATATTTGTATATGTTGATGGAAGCTTGTCTAGGTGGAGAGCTCTGGACCATTCT
CAGGGATAGAGGTTCGTTTGAAGATTCTACAACCAGATTTTACACAGCATGTGTGGTAGAAGCTTTTGCCTATCTGCATTCCAAAGGAAT
CATTTACAGGGACCTCAAGCCAGAAAATCTCATCCTAGATCACCGAGGTTATGCCAAACTGGTTGATTTTGGCTTTGCAAAGAAAATAGG
ATTTGGAAAGAAAACATGGACTTTTTGTGGGACTCCAGAGTATGTAGCCCCAGAGATCATCCTGAACAAAGGCCATGACATTTCAGCCGA
CTACTGGTCACTGGGAATCCTAATGTATGAACTCCTGACTGGCAGCCCACCTTTCTCAGGCCCAGATCCTATGAAAACCTATAACATCAT
ATTGAGGGGGATTGACATGATAGAATTTCCAAAGAAGATTGCCAAAAATGCTGCTAATTTAATTAAAAAACTATGCAGGGACAATCCATC
AGAAAGATTAGGGAATTTGAAAAATGGAGTAAAAGACATTCAAAAGCACAAATGGTTTGAGGGCTTTAACTGGGAAGGCTTAAGAAAAGG
TACCTTGACACCTCCTATAATACCAAGTGTTGCATCACCCACAGACACAAGTAATTTTGACAGTTTCCCTGAGGACAACGATGAACCACC
ACCTGATGACAACTCAGGATGGGATATAGACTTCTAATGTATTTCTCTTACCTGCTTCTGCCTTGCTGAAGACAGCTTTTTCTGAGACAC
AGCTGCCAGCAAACCTGAGGGAAAGAGAGAAGATTAGTGCTCGGGGTCACCATGATGCCTTTGATCGATGCTGCTCCAGTAACTACAGTG
GCATTAGGACTTACCGCTTAGATGACAATAGTGCTCTTTACATGTTTTCTGTTTGAACCTAAAATAGCAGTTGACATGGTGGTCCTGAAG
CAAAGCCTTTCACCAGTAAAAGATGTTTTCTATTGTTGCAATGACCTTGCTTTGCTCTGATTATAATTTGAAAGACTGTAGGAAACACTT
CAATGTAGTATAAGAGTCTGTACCTTGCTGGAATATTCAAGAAGATGAAAGAATAATATATTGGGTACAATAGATTACTATGGTACAGAA
ACTGGGCTATTCCCTTTCTTCAAGTGAAGGCTGTGGGATCTATTACTGCAGGCCGGTGTATATACCATACAAAAGAGGACCACACATCTG
TTGGTCACAGAGTTCATGTCACACCAGTGCTAGAAGTTTCATGATTTTATTTCCCAGCAGTGCTGATGACAAGACTGAATGTTACCTTTT
CTTTCTGACAGATTTTAAAAATTGATATGATAAAAGCACAACTGCTATAGATTCTGCTGAGACCTCTCATAGTAGGTATATATGAGTTTT
CACAGAAGACTGAAAAATAATGCATGATATTTGTTTGTTTTTTTTGATAAATTGGCATGACAGAGTGGGGAAAAAAAGCAATTCACAAAA
CCATTTCATATTTTTTAAAATATTGTGCTTAAAGATGGTCCTGGAAGTAAATGACTAGCAGCCAATTGGTTTTACTTAACATACCCTCAA
ACTGAGGCTTAAAGTATTCCCTTTTATAAAAATAAATGCTTGGGGTAGGGTGGAGTGGGGAGGGATTAAAACCCATCCAAAAAATAAATA
AAAACTATATAGGTGCTATGTATATCTTTCATCTGTAAATGTCAGTGTCTGAACAGACAACACAAATTCAAATCATTATACGTGTAGCCA
GAAACTCAAGCATTTTCACTAAAGTTATTAAACCAAACTCCTGTCCAATTTCACTTATACAACATAGTCAGTCTAGAGTTGAGAGACAAA
GGTAATTATAAACCTATTTGAACTAGCTTCTTGTCTTAGGCCTGAACCAAAAAACAACAAACAAACAAAAAACAAGAATGAAAAACAGAA
ATAAAAGAAGTAGAAAAGACAAAGAAAGAAAGCCCAAAGTCAAAGTTGTTAATATTTACAGGTTTACCAGATCTGGAACATTACTTATTT
GAGGTCAGAGAACAAAACAAGAACCTGGCCAGGTGTTGATTACCTTTTAGTGAATAAGCTGAGTCCATATACTTGTCTAACTAAGAAAGC
AGTACAGAGGAAAACAGGAACCTGATTTTTTTAAAATAAATTTTAAATAAAATAGAATTACTACAATTCTGCAATTTCATACTACCTAAA
AAAGACTAGATTTGAAAATGTCAAGCTGATTTACTTTATTCACATGGAGAAAAGAATCCACAAATTAAACTGAGTCCTTCACTGGCATGC
CAGTTGACTATTATTAGCTGTCATAAGTAACTCAGCCATTTGGAAGCATTTCCTGGACAAAATTACATTATACCTGTGAAGAAAAATATA
GAAGCTTTCAAGCTGTCATTCTGTTTTGGCCCTGTGTGAATTTGGTATATTAAATTGACGCTTGCTTTTTTTTTCAGTAGAGTTTTCTTT
TTAATCAATCAAACGCCTACATTTCTGGAAGAAAAAGTCCAATTAGATCATTACACCTTAACTAAGAAGGCAAATCTTATAAATTTTGCT
TGAATTGTTCTTACTCAAAACTACCTTAGAATATGGTATCTTATGAAAATATAATATTCTTAAAATTTTGGAGGATAAAATGAAAAGGGT
ATAAACTTCAATTAGAACTTTAATCCTAAAATATTGTTATTCTTGTATTTTTGGAGTTTTCCGTCCCTTACAATTTCTCCAAATTGGTCT
ATTCCCCAAGATATCCACTGTTTTCTACAGATTTTAGAATATAAAATTAAACATATCAACCTAAAATCTAGCTATGAATGTTATTTCAAG
AGTTTTATATTTTTAATTGGCTTTTTAAAAATATGTAATTCCAATATTATAGTGAATGTTCAGTAACTTTTGTTGAAAGATAATGTGGTT
TAGGCTTGCTAAAGAAAGGCTTGCTAGAATACTAAATTTACCTTGTTATTTGGAAAGAGAATCTGCTCCTATAACGTTTTAAAAATCCCC
AAAGTCCCAGAGATTAGCACTTGCTATGGATTTTGGAACTATGGTTCAAGTCTAAGACAACCAATATGAATAAGTTCAATGGAGAAGGAA
GAAGTAGCATTCAGCACAAGAAACTGTAGATTGTTTCTCCCACTTGTTACTGCATCTTTGTTCATTTCACCCATAGCATTGCATTTGATG
TCTGAAGTAATTACCACAAAATAAAGGTAAACTACATCTTCCAAGATGTACCAACAGAAAACATTCGTCTAATTTTGTCAACATTGAATT
TTTAGGATTTAAATCTTGTCTTAATGAAGACTCTAGGGCTAAAATTCATGGTCAGTTCCATAAAATGCATCTCACTTTATTTCTGAATTT
TTCACAACCCCTCTATTTTCTTACATTAAAGAACATCTGGATAAGTTAGAATAGTGCCAACTTGTTTGATTTGTTATATGATTTTCTTGT
TAATGTGTTGAGTATGGGAAATAAGGGCTTTCTGTGTGTCTTGACTCACAGGAAAACTGAAACTGCCAAGGGAAGCAACATTAAAACAAC
TGGGATAGATTGAATACATTTGAAAAAATAATTTCTGGAAAAACGCTATACATGCTTTTTATGTTTATATCTTCTTTCTTATTAAGACAT
GAATCAGATCCATGTGGCATTCAAAACAAATTTATTTTGGTTATATTCTTTACAAGTCATAATTTTTACCTAAAATTGTGGAATATGCAT
GTGAATTACACATGTGTAGTAATAAACTCAACTATTGAATTTTTCCTGTTTCATTTCTAAATGACTGAACTGATGGTAAACAAATTTAAT
GAAGTCAGCTACCATGTTGAAAATAAGGATATTAGAACTGATTTCATACAATAGAGGTGATCTGTGCATTATCCATAACAACGTTTTCTT
TCACTATAGGACCACAGACAAATATTTATGTAAATAGGTATTTTTGTGTGATATTTTGTGGTACATATAACTTTTTTTAGTGTTTCACAG
CATTATTATTTCATTTTATTTGTATTGAATAATGTTTTTAGGTCCAAGTAGACTTGAATTAATGTCATAATTGTCAGTATTATTGAAAAT
TATGTCAACTGTACTGTTATTCATCTGTCCCATAGTTTAGAACATGACCTGGCTATCTGGCATTGTTGCAAGTGCCTTAAATTCATGGCA
TCCTATTAAAAAAACAAATTTGGTGTTATGCTGCATGACAAAGACAAACACACCTCAAAATGTTGTCCTTTCTTAGCTTGCTGCGTTTTA
CAGTTCTTTCTGCTAACAATTTATAAGCCTTTATTATATAATATTGATGAATTACAGAAATGATGAAGTTGTTCTCTTATTTCTGTTAAA
TGTACCAGAGCTGTGTATCTGTTAATGAGATACAGCGTCATTTCTGTGAAATGTATAAATGTATGTGCAGGTCAAATTAATATATGACAT
TCTATCAGTCTGTATACAGGTATTCCTGTTTTGCTAAGCTGTGCAGATTCTGTAAAAATAAATTAGTGCAGTCAAGTTCTAACATATCTC
ATTTTATAGACTCCATTGACAATGGTCCAACCGAAAAGAAAAATTGGAAATGACTGCTAACCAGACCTCGTTATGAAACCAATGATGAAA
AAGTCACTTGGTGCACCTCTCAACAAAACAGGATGCTTTTTCCGAGTTCTTGTATATGCAAATCATTTACGAGGCAAGTTTTCAACAGAC
CTAGAAAGCAAAACATTGAAAGTGTGTTGTTAGCCCTCCTCTCTGCCCCTGAATCAACAGACAGAGCTCTGGGACCTTGGCAATGACTCA
GAGGTTGGGGCTTTCTGAGTAAAGGGACATTTCTTTAAGCATCATCTATCAAATTTATTTCAATGTATGATGTTTTTACAACTGGTCAGT
TCTTTTGTATTCTTACAGCTATGGTTATTTGATTGTCCTCTTACAATTTGTTCTACATGAAAGAGTTCTTTGTTAGTCAGAATGCAACAA
ACTGTCATCAAATGGTCATTGACCACTTGCACTCTTTTGATGTAGATTAAAAACTTTTTCATAAATTTACCTGCTTTGATTTGCTCTGTA

>90945_90945_1_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000260867_PRKG1_chr10_53564345_ENST00000373980_length(amino acids)=660AA_BP=0
MEGGGGSGNKTTGGLAGFFGAGGAGYSHADLAGVPLTGMNPLSPYLNVDPRYLVQDTDEFILPTGANKTRGRFELAFFTIGGCCMTGAAF
GAMNGLRLGLKETQNMAWSKPRNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTALVNVKLWA
IDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFL
RTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGF
GRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTT
RFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYEL
LTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVA

--------------------------------------------------------------
>90945_90945_2_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000260867_PRKG1_chr10_53564345_ENST00000373985_length(transcript)=6557nt_BP=638nt
GAAGGTCAGCGTGTGAAGTAGGCGCTGGCAACGCGGGGTTACCCGCTGTTATTGAGGAGTAACGGCCCAGCGGACCACCCAGGCTTGAGG
CAGCGGCGGGAACCACTCGGTTTGCTGCGATACCATGGAAGGAGGCGGGGGAAGCGGCAACAAAACCACAGGGGGATTGGCCGGCTTTTT
CGGAGCCGGCGGAGCAGGTTACTCGCACGCGGATTTGGCTGGCGTCCCGCTAACTGGTATGAACCCTCTGTCTCCTTATTTAAATGTGGA
TCCACGATACCTCGTGCAGGATACAGATGAGTTTATTTTACCTACCGGAGCTAATAAAACCCGGGGCAGATTTGAGCTGGCCTTCTTTAC
GATTGGAGGATGTTGCATGACAGGGGCTGCGTTTGGTGCAATGAATGGTCTTCGGCTAGGATTGAAGGAAACCCAGAACATGGCCTGGTC
CAAACCAAGAAATGTACAGATTTTGAATATGGTGACTAGGCAAGGGGCACTTTGGGCTAATACTCTAGGTTCTCTGGCTTTGCTCTATAG
TGCATTTGGTGTCATCATTGAGAAAACACGAGGTGCAGAAGATGACCTTAACACAGTAGCAGCTGGAACCATGACAGGCATGTTGTATAA
ATGTACAGCTCTTGTAAATGTAAAACTCTGGGCCATTGATCGACAATGTTTTCAAACAATAATGATGAGGACAGGACTCATCAAGCATAC
CGAGTATATGGAATTTTTAAAAAGCGTTCCAACATTCCAGAGCCTTCCTGAAGAGATCCTCAGCAAGCTTGCTGATGTCCTTGAAGAGAC
CCACTATGAAAATGGAGAATATATTATCAGGCAAGGTGCAAGAGGGGACACCTTCTTTATCATCAGCAAAGGAACGGTAAATGTCACTCG
TGAAGACTCACCGAGTGAAGACCCAGTCTTTCTTAGAACTTTAGGAAAAGGAGACTGGTTTGGAGAGAAAGCCTTGCAGGGGGAAGATGT
GAGAACAGCAAACGTAATTGCTGCAGAAGCTGTAACCTGCCTTGTGATTGACAGAGACTCTTTTAAACATTTGATTGGAGGGCTGGATGA
TGTTTCTAATAAAGCATATGAAGATGCAGAAGCTAAAGCAAAATATGAAGCTGAAGCGGCTTTCTTCGCCAACCTGAAGCTGTCTGATTT
CAACATCATTGATACCCTTGGAGTTGGAGGTTTCGGACGAGTAGAACTGGTCCAGTTGAAAAGTGAAGAATCCAAAACGTTTGCAATGAA
GATTCTCAAGAAACGTCACATTGTGGACACAAGACAGCAGGAGCACATCCGCTCAGAGAAGCAGATCATGCAGGGGGCTCATTCCGATTT
CATAGTGAGACTGTACAGAACATTTAAGGACAGCAAATATTTGTATATGTTGATGGAAGCTTGTCTAGGTGGAGAGCTCTGGACCATTCT
CAGGGATAGAGGTTCGTTTGAAGATTCTACAACCAGATTTTACACAGCATGTGTGGTAGAAGCTTTTGCCTATCTGCATTCCAAAGGAAT
CATTTACAGGGACCTCAAGCCAGAAAATCTCATCCTAGATCACCGAGGTTATGCCAAACTGGTTGATTTTGGCTTTGCAAAGAAAATAGG
ATTTGGAAAGAAAACATGGACTTTTTGTGGGACTCCAGAGTATGTAGCCCCAGAGATCATCCTGAACAAAGGCCATGACATTTCAGCCGA
CTACTGGTCACTGGGAATCCTAATGTATGAACTCCTGACTGGCAGCCCACCTTTCTCAGGCCCAGATCCTATGAAAACCTATAACATCAT
ATTGAGGGGGATTGACATGATAGAATTTCCAAAGAAGATTGCCAAAAATGCTGCTAATTTAATTAAAAAACTATGCAGGGACAATCCATC
AGAAAGATTAGGGAATTTGAAAAATGGAGTAAAAGACATTCAAAAGCACAAATGGTTTGAGGGCTTTAACTGGGAAGGCTTAAGAAAAGG
TACCTTGACACCTCCTATAATACCAAGTGTTGCATCACCCACAGACACAAGTAATTTTGACAGTTTCCCTGAGGACAACGATGAACCACC
ACCTGATGACAACTCAGGATGGGATATAGACTTCTAATGTATTTCTCTTACCTGCTTCTGCCTTGCTGAAGACAGCTTTTTCTGAGACAC
AGCTGCCAGCAAACCTGAGGGAAAGAGAGAAGATTAGTGCTCGGGGTCACCATGATGCCTTTGATCGATGCTGCTCCAGTAACTACAGTG
GCATTAGGACTTACCGCTTAGATGACAATAGTGCTCTTTACATGTTTTCTGTTTGAACCTAAAATAGCAGTTGACATGGTGGTCCTGAAG
CAAAGCCTTTCACCAGTAAAAGATGTTTTCTATTGTTGCAATGACCTTGCTTTGCTCTGATTATAATTTGAAAGACTGTAGGAAACACTT
CAATGTAGTATAAGAGTCTGTACCTTGCTGGAATATTCAAGAAGATGAAAGAATAATATATTGGGTACAATAGATTACTATGGTACAGAA
ACTGGGCTATTCCCTTTCTTCAAGTGAAGGCTGTGGGATCTATTACTGCAGGCCGGTGTATATACCATACAAAAGAGGACCACACATCTG
TTGGTCACAGAGTTCATGTCACACCAGTGCTAGAAGTTTCATGATTTTATTTCCCAGCAGTGCTGATGACAAGACTGAATGTTACCTTTT
CTTTCTGACAGATTTTAAAAATTGATATGATAAAAGCACAACTGCTATAGATTCTGCTGAGACCTCTCATAGTAGGTATATATGAGTTTT
CACAGAAGACTGAAAAATAATGCATGATATTTGTTTGTTTTTTTTGATAAATTGGCATGACAGAGTGGGGAAAAAAAGCAATTCACAAAA
CCATTTCATATTTTTTAAAATATTGTGCTTAAAGATGGTCCTGGAAGTAAATGACTAGCAGCCAATTGGTTTTACTTAACATACCCTCAA
ACTGAGGCTTAAAGTATTCCCTTTTATAAAAATAAATGCTTGGGGTAGGGTGGAGTGGGGAGGGATTAAAACCCATCCAAAAAATAAATA
AAAACTATATAGGTGCTATGTATATCTTTCATCTGTAAATGTCAGTGTCTGAACAGACAACACAAATTCAAATCATTATACGTGTAGCCA
GAAACTCAAGCATTTTCACTAAAGTTATTAAACCAAACTCCTGTCCAATTTCACTTATACAACATAGTCAGTCTAGAGTTGAGAGACAAA
GGTAATTATAAACCTATTTGAACTAGCTTCTTGTCTTAGGCCTGAACCAAAAAACAACAAACAAACAAAAAACAAGAATGAAAAACAGAA
ATAAAAGAAGTAGAAAAGACAAAGAAAGAAAGCCCAAAGTCAAAGTTGTTAATATTTACAGGTTTACCAGATCTGGAACATTACTTATTT
GAGGTCAGAGAACAAAACAAGAACCTGGCCAGGTGTTGATTACCTTTTAGTGAATAAGCTGAGTCCATATACTTGTCTAACTAAGAAAGC
AGTACAGAGGAAAACAGGAACCTGATTTTTTTAAAATAAATTTTAAATAAAATAGAATTACTACAATTCTGCAATTTCATACTACCTAAA
AAAGACTAGATTTGAAAATGTCAAGCTGATTTACTTTATTCACATGGAGAAAAGAATCCACAAATTAAACTGAGTCCTTCACTGGCATGC
CAGTTGACTATTATTAGCTGTCATAAGTAACTCAGCCATTTGGAAGCATTTCCTGGACAAAATTACATTATACCTGTGAAGAAAAATATA
GAAGCTTTCAAGCTGTCATTCTGTTTTGGCCCTGTGTGAATTTGGTATATTAAATTGACGCTTGCTTTTTTTTTCAGTAGAGTTTTCTTT
TTAATCAATCAAACGCCTACATTTCTGGAAGAAAAAGTCCAATTAGATCATTACACCTTAACTAAGAAGGCAAATCTTATAAATTTTGCT
TGAATTGTTCTTACTCAAAACTACCTTAGAATATGGTATCTTATGAAAATATAATATTCTTAAAATTTTGGAGGATAAAATGAAAAGGGT
ATAAACTTCAATTAGAACTTTAATCCTAAAATATTGTTATTCTTGTATTTTTGGAGTTTTCCGTCCCTTACAATTTCTCCAAATTGGTCT
ATTCCCCAAGATATCCACTGTTTTCTACAGATTTTAGAATATAAAATTAAACATATCAACCTAAAATCTAGCTATGAATGTTATTTCAAG
AGTTTTATATTTTTAATTGGCTTTTTAAAAATATGTAATTCCAATATTATAGTGAATGTTCAGTAACTTTTGTTGAAAGATAATGTGGTT
TAGGCTTGCTAAAGAAAGGCTTGCTAGAATACTAAATTTACCTTGTTATTTGGAAAGAGAATCTGCTCCTATAACGTTTTAAAAATCCCC
AAAGTCCCAGAGATTAGCACTTGCTATGGATTTTGGAACTATGGTTCAAGTCTAAGACAACCAATATGAATAAGTTCAATGGAGAAGGAA
GAAGTAGCATTCAGCACAAGAAACTGTAGATTGTTTCTCCCACTTGTTACTGCATCTTTGTTCATTTCACCCATAGCATTGCATTTGATG
TCTGAAGTAATTACCACAAAATAAAGGTAAACTACATCTTCCAAGATGTACCAACAGAAAACATTCGTCTAATTTTGTCAACATTGAATT
TTTAGGATTTAAATCTTGTCTTAATGAAGACTCTAGGGCTAAAATTCATGGTCAGTTCCATAAAATGCATCTCACTTTATTTCTGAATTT
TTCACAACCCCTCTATTTTCTTACATTAAAGAACATCTGGATAAGTTAGAATAGTGCCAACTTGTTTGATTTGTTATATGATTTTCTTGT
TAATGTGTTGAGTATGGGAAATAAGGGCTTTCTGTGTGTCTTGACTCACAGGAAAACTGAAACTGCCAAGGGAAGCAACATTAAAACAAC
TGGGATAGATTGAATACATTTGAAAAAATAATTTCTGGAAAAACGCTATACATGCTTTTTATGTTTATATCTTCTTTCTTATTAAGACAT
GAATCAGATCCATGTGGCATTCAAAACAAATTTATTTTGGTTATATTCTTTACAAGTCATAATTTTTACCTAAAATTGTGGAATATGCAT
GTGAATTACACATGTGTAGTAATAAACTCAACTATTGAATTTTTCCTGTTTCATTTCTAAATGACTGAACTGATGGTAAACAAATTTAAT
GAAGTCAGCTACCATGTTGAAAATAAGGATATTAGAACTGATTTCATACAATAGAGGTGATCTGTGCATTATCCATAACAACGTTTTCTT
TCACTATAGGACCACAGACAAATATTTATGTAAATAGGTATTTTTGTGTGATATTTTGTGGTACATATAACTTTTTTTAGTGTTTCACAG
CATTATTATTTCATTTTATTTGTATTGAATAATGTTTTTAGGTCCAAGTAGACTTGAATTAATGTCATAATTGTCAGTATTATTGAAAAT
TATGTCAACTGTACTGTTATTCATCTGTCCCATAGTTTAGAACATGACCTGGCTATCTGGCATTGTTGCAAGTGCCTTAAATTCATGGCA
TCCTATTAAAAAAACAAATTTGGTGTTATGCTGCATGACAAAGACAAACACACCTCAAAATGTTGTCCTTTCTTAGCTTGCTGCGTTTTA
CAGTTCTTTCTGCTAACAATTTATAAGCCTTTATTATATAATATTGATGAATTACAGAAATGATGAAGTTGTTCTCTTATTTCTGTTAAA
TGTACCAGAGCTGTGTATCTGTTAATGAGATACAGCGTCATTTCTGTGAAATGTATAAATGTATGTGCAGGTCAAATTAATATATGACAT
TCTATCAGTCTGTATACAGGTATTCCTGTTTTGCTAAGCTGTGCAGATTCTGTAAAAATAAATTAGTGCAGTCAAGTTCTAACATATCTC
ATTTTATAGACTCCATTGACAATGGTCCAACCGAAAAGAAAAATTGGAAATGACTGCTAACCAGACCTCGTTATGAAACCAATGATGAAA
AAGTCACTTGGTGCACCTCTCAACAAAACAGGATGCTTTTTCCGAGTTCTTGTATATGCAAATCATTTACGAGGCAAGTTTTCAACAGAC
CTAGAAAGCAAAACATTGAAAGTGTGTTGTTAGCCCTCCTCTCTGCCCCTGAATCAACAGACAGAGCTCTGGGACCTTGGCAATGACTCA
GAGGTTGGGGCTTTCTGAGTAAAGGGACATTTCTTTAAGCATCATCTATCAAATTTATTTCAATGTATGATGTTTTTACAACTGGTCAGT
TCTTTTGTATTCTTACAGCTATGGTTATTTGATTGTCCTCTTACAATTTGTTCTACATGAAAGAGTTCTTTGTTAGTCAGAATGCAACAA
ACTGTCATCAAATGGTCATTGACCACTTGCACTCTTTTGATGTAGATTAAAAACTTTTTCATAAATTTACCTGCTTTGATTTGCTCTGTA

>90945_90945_2_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000260867_PRKG1_chr10_53564345_ENST00000373985_length(amino acids)=660AA_BP=0
MEGGGGSGNKTTGGLAGFFGAGGAGYSHADLAGVPLTGMNPLSPYLNVDPRYLVQDTDEFILPTGANKTRGRFELAFFTIGGCCMTGAAF
GAMNGLRLGLKETQNMAWSKPRNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTALVNVKLWA
IDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFL
RTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGF
GRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTT
RFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYEL
LTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVA

--------------------------------------------------------------
>90945_90945_3_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000260867_PRKG1_chr10_53564345_ENST00000401604_length(transcript)=3721nt_BP=638nt
GAAGGTCAGCGTGTGAAGTAGGCGCTGGCAACGCGGGGTTACCCGCTGTTATTGAGGAGTAACGGCCCAGCGGACCACCCAGGCTTGAGG
CAGCGGCGGGAACCACTCGGTTTGCTGCGATACCATGGAAGGAGGCGGGGGAAGCGGCAACAAAACCACAGGGGGATTGGCCGGCTTTTT
CGGAGCCGGCGGAGCAGGTTACTCGCACGCGGATTTGGCTGGCGTCCCGCTAACTGGTATGAACCCTCTGTCTCCTTATTTAAATGTGGA
TCCACGATACCTCGTGCAGGATACAGATGAGTTTATTTTACCTACCGGAGCTAATAAAACCCGGGGCAGATTTGAGCTGGCCTTCTTTAC
GATTGGAGGATGTTGCATGACAGGGGCTGCGTTTGGTGCAATGAATGGTCTTCGGCTAGGATTGAAGGAAACCCAGAACATGGCCTGGTC
CAAACCAAGAAATGTACAGATTTTGAATATGGTGACTAGGCAAGGGGCACTTTGGGCTAATACTCTAGGTTCTCTGGCTTTGCTCTATAG
TGCATTTGGTGTCATCATTGAGAAAACACGAGGTGCAGAAGATGACCTTAACACAGTAGCAGCTGGAACCATGACAGGCATGTTGTATAA
ATGTACAGCTCTTGTAAATGTAAAACTCTGGGCCATTGATCGACAATGTTTTCAAACAATAATGATGAGGACAGGACTCATCAAGCATAC
CGAGTATATGGAATTTTTAAAAAGCGTTCCAACATTCCAGAGCCTTCCTGAAGAGATCCTCAGCAAGCTTGCTGATGTCCTTGAAGAGAC
CCACTATGAAAATGGAGAATATATTATCAGGCAAGGTGCAAGAGGGGACACCTTCTTTATCATCAGCAAAGGAACGGTAAATGTCACTCG
TGAAGACTCACCGAGTGAAGACCCAGTCTTTCTTAGAACTTTAGGAAAAGGAGACTGGTTTGGAGAGAAAGCCTTGCAGGGGGAAGATGT
GAGAACAGCAAACGTAATTGCTGCAGAAGCTGTAACCTGCCTTGTGATTGACAGAGACTCTTTTAAACATTTGATTGGAGGGCTGGATGA
TGTTTCTAATAAAGCATATGAAGATGCAGAAGCTAAAGCAAAATATGAAGCTGAAGCGGCTTTCTTCGCCAACCTGAAGCTGTCTGATTT
CAACATCATTGATACCCTTGGAGTTGGAGGTTTCGGACGAGTAGAACTGGTCCAGTTGAAAAGTGAAGAATCCAAAACGTTTGCAATGAA
GATTCTCAAGAAACGTCACATTGTGGACACAAGACAGCAGGAGCACATCCGCTCAGAGAAGCAGATCATGCAGGGGGCTCATTCCGATTT
CATAGTGAGACTGTACAGAACATTTAAGGACAGCAAATATTTGTATATGTTGATGGAAGCTTGTCTAGGTGGAGAGCTCTGGACCATTCT
CAGGGATAGAGGTTCGTTTGAAGATTCTACAACCAGATTTTACACAGCATGTGTGGTAGAAGCTTTTGCCTATCTGCATTCCAAAGGAAT
CATTTACAGGGACCTCAAGCCAGAAAATCTCATCCTAGATCACCGAGGTTATGCCAAACTGGTTGATTTTGGCTTTGCAAAGAAAATAGG
ATTTGGAAAGAAAACATGGACTTTTTGTGGGACTCCAGAGTATGTAGCCCCAGAGATCATCCTGAACAAAGGCCATGACATTTCAGCCGA
CTACTGGTCACTGGGAATCCTAATGTATGAACTCCTGACTGGCAGCCCACCTTTCTCAGGCCCAGATCCTATGAAAACCTATAACATCAT
ATTGAGGGGGATTGACATGATAGAATTTCCAAAGAAGATTGCCAAAAATGCTGCTAATTTAATTAAAAAACTATGCAGGGACAATCCATC
AGAAAGATTAGGGAATTTGAAAAATGGAGTAAAAGACATTCAAAAGCACAAATGGTTTGAGGGCTTTAACTGGGAAGGCTTAAGAAAAGG
TACCTTGACACCTCCTATAATACCAAGTGTTGCATCACCCACAGACACAAGTAATTTTGACAGTTTCCCTGAGGACAACGATGAACCACC
ACCTGATGACAACTCAGGATGGGATATAGACTTCTAATGTATTTCTCTTACCTGCTTCTGCCTTGCTGAAGACAGCTTTTTCTGAGACAC
AGCTGCCAGCAAACCTGAGGGAAAGAGAGAAGATTAGTGCTCGGGGTCACCATGATGCCTTTGATCGATGCTGCTCCAGTAACTACAGTG
GCATTAGGACTTACCGCTTAGATGACAATAGTGCTCTTTACATGTTTTCTGTTTGAACCTAAAATAGCAGTTGACATGGTGGTCCTGAAG
CAAAGCCTTTCACCAGTAAAAGATGTTTTCTATTGTTGCAATGACCTTGCTTTGCTCTGATTATAATTTGAAAGACTGTAGGAAACACTT
CAATGTAGTATAAGAGTCTGTACCTTGCTGGAATATTCAAGAAGATGAAAGAATAATATATTGGGTACAATAGATTACTATGGTACAGAA
ACTGGGCTATTCCCTTTCTTCAAGTGAAGGCTGTGGGATCTATTACTGCAGGCCGGTGTATATACCATACAAAAGAGGACCACACATCTG
TTGGTCACAGAGTTCATGTCACACCAGTGCTAGAAGTTTCATGATTTTATTTCCCAGCAGTGCTGATGACAAGACTGAATGTTACCTTTT
CTTTCTGACAGATTTTAAAAATTGATATGATAAAAGCACAACTGCTATAGATTCTGCTGAGACCTCTCATAGTAGGTATATATGAGTTTT
CACAGAAGACTGAAAAATAATGCATGATATTTGTTTGTTTTTTTTGATAAATTGGCATGACAGAGTGGGGAAAAAAAGCAATTCACAAAA
CCATTTCATATTTTTTAAAATATTGTGCTTAAAGATGGTCCTGGAAGTAAATGACTAGCAGCCAATTGGTTTTACTTAACATACCCTCAA
ACTGAGGCTTAAAGTATTCCCTTTTATAAAAATAAATGCTTGGGGTAGGGTGGAGTGGGGAGGGATTAAAACCCATCCAAAAAATAAATA
AAAACTATATAGGTGCTATGTATATCTTTCATCTGTAAATGTCAGTGTCTGAACAGACAACACAAATTCAAATCATTATACGTGTAGCCA
GAAACTCAAGCATTTTCACTAAAGTTATTAAACCAAACTCCTGTCCAATTTCACTTATACAACATAGTCAGTCTAGAGTTGAGAGACAAA
GGTAATTATAAACCTATTTGAACTAGCTTCTTGTCTTAGGCCTGAACCAAAAAACAACAAACAAACAAAAAACAAGAATGAAAAACAGAA
ATAAAAGAAGTAGAAAAGACAAAGAAAGAAAGCCCAAAGTCAAAGTTGTTAATATTTACAGGTTTACCAGATCTGGAACATTACTTATTT
GAGGTCAGAGAACAAAACAAGAACCTGGCCAGGTGTTGATTACCTTTTAGTGAATAAGCTGAGTCCATATACTTGTCTAACTAAGAAAGC
AGTACAGAGGAAAACAGGAACCTGATTTTTTTAAAATAAATTTTAAATAAAATAGAATTACTACAATTCTGCAATTTCATACTACCTAAA
AAAGACTAGATTTGAAAATGTCAAGCTGATTTACTTTATTCACATGGAGAAAAGAATCCACAAATTAAACTGAGTCCTTCACTGGCATGC

>90945_90945_3_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000260867_PRKG1_chr10_53564345_ENST00000401604_length(amino acids)=660AA_BP=0
MEGGGGSGNKTTGGLAGFFGAGGAGYSHADLAGVPLTGMNPLSPYLNVDPRYLVQDTDEFILPTGANKTRGRFELAFFTIGGCCMTGAAF
GAMNGLRLGLKETQNMAWSKPRNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTALVNVKLWA
IDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFL
RTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGF
GRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTT
RFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYEL
LTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVA

--------------------------------------------------------------
>90945_90945_4_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000374064_PRKG1_chr10_53564345_ENST00000373980_length(transcript)=6411nt_BP=492nt
AGGTCAGCGTGTGAAGTAGGCGCTGGCAACGCGGGGTTACCCGCTGTTATTGAGGAGTAACGGCCCAGCGGACCACCCAGGCTTGAGGCA
GCGGCGGGAACCACTCGGTTTGCTGCGATACCATGGAAGGAGGCGGGGGAAGCGGCAACAAAACCACAGGGGGATTGGCCGGCTTTTTCG
GAGCCGGCGGAGCAGGTTACTCGCACGCGGATTTGGCTGGCGTCCCGCTAACTGGTATGAACCCTCTGTCTCCTTATTTAAATGTGGATC
CACGATACCTCGTGCAGGATACAGATGAGTTTATTTTACCTACCGGAGCTAATAAAACCCGGGGCAGATTTGAGCTGGCCTTCTTTACGA
TTGGAGGATGTTGCATGACAGCTTTGCTCTATAGTGCATTTGGTGTCATCATTGAGAAAACACGAGGTGCAGAAGATGACCTTAACACAG
TAGCAGCTGGAACCATGACAGGCATGTTGTATAAATGTACAGCTCTTGTAAATGTAAAACTCTGGGCCATTGATCGACAATGTTTTCAAA
CAATAATGATGAGGACAGGACTCATCAAGCATACCGAGTATATGGAATTTTTAAAAAGCGTTCCAACATTCCAGAGCCTTCCTGAAGAGA
TCCTCAGCAAGCTTGCTGATGTCCTTGAAGAGACCCACTATGAAAATGGAGAATATATTATCAGGCAAGGTGCAAGAGGGGACACCTTCT
TTATCATCAGCAAAGGAACGGTAAATGTCACTCGTGAAGACTCACCGAGTGAAGACCCAGTCTTTCTTAGAACTTTAGGAAAAGGAGACT
GGTTTGGAGAGAAAGCCTTGCAGGGGGAAGATGTGAGAACAGCAAACGTAATTGCTGCAGAAGCTGTAACCTGCCTTGTGATTGACAGAG
ACTCTTTTAAACATTTGATTGGAGGGCTGGATGATGTTTCTAATAAAGCATATGAAGATGCAGAAGCTAAAGCAAAATATGAAGCTGAAG
CGGCTTTCTTCGCCAACCTGAAGCTGTCTGATTTCAACATCATTGATACCCTTGGAGTTGGAGGTTTCGGACGAGTAGAACTGGTCCAGT
TGAAAAGTGAAGAATCCAAAACGTTTGCAATGAAGATTCTCAAGAAACGTCACATTGTGGACACAAGACAGCAGGAGCACATCCGCTCAG
AGAAGCAGATCATGCAGGGGGCTCATTCCGATTTCATAGTGAGACTGTACAGAACATTTAAGGACAGCAAATATTTGTATATGTTGATGG
AAGCTTGTCTAGGTGGAGAGCTCTGGACCATTCTCAGGGATAGAGGTTCGTTTGAAGATTCTACAACCAGATTTTACACAGCATGTGTGG
TAGAAGCTTTTGCCTATCTGCATTCCAAAGGAATCATTTACAGGGACCTCAAGCCAGAAAATCTCATCCTAGATCACCGAGGTTATGCCA
AACTGGTTGATTTTGGCTTTGCAAAGAAAATAGGATTTGGAAAGAAAACATGGACTTTTTGTGGGACTCCAGAGTATGTAGCCCCAGAGA
TCATCCTGAACAAAGGCCATGACATTTCAGCCGACTACTGGTCACTGGGAATCCTAATGTATGAACTCCTGACTGGCAGCCCACCTTTCT
CAGGCCCAGATCCTATGAAAACCTATAACATCATATTGAGGGGGATTGACATGATAGAATTTCCAAAGAAGATTGCCAAAAATGCTGCTA
ATTTAATTAAAAAACTATGCAGGGACAATCCATCAGAAAGATTAGGGAATTTGAAAAATGGAGTAAAAGACATTCAAAAGCACAAATGGT
TTGAGGGCTTTAACTGGGAAGGCTTAAGAAAAGGTACCTTGACACCTCCTATAATACCAAGTGTTGCATCACCCACAGACACAAGTAATT
TTGACAGTTTCCCTGAGGACAACGATGAACCACCACCTGATGACAACTCAGGATGGGATATAGACTTCTAATGTATTTCTCTTACCTGCT
TCTGCCTTGCTGAAGACAGCTTTTTCTGAGACACAGCTGCCAGCAAACCTGAGGGAAAGAGAGAAGATTAGTGCTCGGGGTCACCATGAT
GCCTTTGATCGATGCTGCTCCAGTAACTACAGTGGCATTAGGACTTACCGCTTAGATGACAATAGTGCTCTTTACATGTTTTCTGTTTGA
ACCTAAAATAGCAGTTGACATGGTGGTCCTGAAGCAAAGCCTTTCACCAGTAAAAGATGTTTTCTATTGTTGCAATGACCTTGCTTTGCT
CTGATTATAATTTGAAAGACTGTAGGAAACACTTCAATGTAGTATAAGAGTCTGTACCTTGCTGGAATATTCAAGAAGATGAAAGAATAA
TATATTGGGTACAATAGATTACTATGGTACAGAAACTGGGCTATTCCCTTTCTTCAAGTGAAGGCTGTGGGATCTATTACTGCAGGCCGG
TGTATATACCATACAAAAGAGGACCACACATCTGTTGGTCACAGAGTTCATGTCACACCAGTGCTAGAAGTTTCATGATTTTATTTCCCA
GCAGTGCTGATGACAAGACTGAATGTTACCTTTTCTTTCTGACAGATTTTAAAAATTGATATGATAAAAGCACAACTGCTATAGATTCTG
CTGAGACCTCTCATAGTAGGTATATATGAGTTTTCACAGAAGACTGAAAAATAATGCATGATATTTGTTTGTTTTTTTTGATAAATTGGC
ATGACAGAGTGGGGAAAAAAAGCAATTCACAAAACCATTTCATATTTTTTAAAATATTGTGCTTAAAGATGGTCCTGGAAGTAAATGACT
AGCAGCCAATTGGTTTTACTTAACATACCCTCAAACTGAGGCTTAAAGTATTCCCTTTTATAAAAATAAATGCTTGGGGTAGGGTGGAGT
GGGGAGGGATTAAAACCCATCCAAAAAATAAATAAAAACTATATAGGTGCTATGTATATCTTTCATCTGTAAATGTCAGTGTCTGAACAG
ACAACACAAATTCAAATCATTATACGTGTAGCCAGAAACTCAAGCATTTTCACTAAAGTTATTAAACCAAACTCCTGTCCAATTTCACTT
ATACAACATAGTCAGTCTAGAGTTGAGAGACAAAGGTAATTATAAACCTATTTGAACTAGCTTCTTGTCTTAGGCCTGAACCAAAAAACA
ACAAACAAACAAAAAACAAGAATGAAAAACAGAAATAAAAGAAGTAGAAAAGACAAAGAAAGAAAGCCCAAAGTCAAAGTTGTTAATATT
TACAGGTTTACCAGATCTGGAACATTACTTATTTGAGGTCAGAGAACAAAACAAGAACCTGGCCAGGTGTTGATTACCTTTTAGTGAATA
AGCTGAGTCCATATACTTGTCTAACTAAGAAAGCAGTACAGAGGAAAACAGGAACCTGATTTTTTTAAAATAAATTTTAAATAAAATAGA
ATTACTACAATTCTGCAATTTCATACTACCTAAAAAAGACTAGATTTGAAAATGTCAAGCTGATTTACTTTATTCACATGGAGAAAAGAA
TCCACAAATTAAACTGAGTCCTTCACTGGCATGCCAGTTGACTATTATTAGCTGTCATAAGTAACTCAGCCATTTGGAAGCATTTCCTGG
ACAAAATTACATTATACCTGTGAAGAAAAATATAGAAGCTTTCAAGCTGTCATTCTGTTTTGGCCCTGTGTGAATTTGGTATATTAAATT
GACGCTTGCTTTTTTTTTCAGTAGAGTTTTCTTTTTAATCAATCAAACGCCTACATTTCTGGAAGAAAAAGTCCAATTAGATCATTACAC
CTTAACTAAGAAGGCAAATCTTATAAATTTTGCTTGAATTGTTCTTACTCAAAACTACCTTAGAATATGGTATCTTATGAAAATATAATA
TTCTTAAAATTTTGGAGGATAAAATGAAAAGGGTATAAACTTCAATTAGAACTTTAATCCTAAAATATTGTTATTCTTGTATTTTTGGAG
TTTTCCGTCCCTTACAATTTCTCCAAATTGGTCTATTCCCCAAGATATCCACTGTTTTCTACAGATTTTAGAATATAAAATTAAACATAT
CAACCTAAAATCTAGCTATGAATGTTATTTCAAGAGTTTTATATTTTTAATTGGCTTTTTAAAAATATGTAATTCCAATATTATAGTGAA
TGTTCAGTAACTTTTGTTGAAAGATAATGTGGTTTAGGCTTGCTAAAGAAAGGCTTGCTAGAATACTAAATTTACCTTGTTATTTGGAAA
GAGAATCTGCTCCTATAACGTTTTAAAAATCCCCAAAGTCCCAGAGATTAGCACTTGCTATGGATTTTGGAACTATGGTTCAAGTCTAAG
ACAACCAATATGAATAAGTTCAATGGAGAAGGAAGAAGTAGCATTCAGCACAAGAAACTGTAGATTGTTTCTCCCACTTGTTACTGCATC
TTTGTTCATTTCACCCATAGCATTGCATTTGATGTCTGAAGTAATTACCACAAAATAAAGGTAAACTACATCTTCCAAGATGTACCAACA
GAAAACATTCGTCTAATTTTGTCAACATTGAATTTTTAGGATTTAAATCTTGTCTTAATGAAGACTCTAGGGCTAAAATTCATGGTCAGT
TCCATAAAATGCATCTCACTTTATTTCTGAATTTTTCACAACCCCTCTATTTTCTTACATTAAAGAACATCTGGATAAGTTAGAATAGTG
CCAACTTGTTTGATTTGTTATATGATTTTCTTGTTAATGTGTTGAGTATGGGAAATAAGGGCTTTCTGTGTGTCTTGACTCACAGGAAAA
CTGAAACTGCCAAGGGAAGCAACATTAAAACAACTGGGATAGATTGAATACATTTGAAAAAATAATTTCTGGAAAAACGCTATACATGCT
TTTTATGTTTATATCTTCTTTCTTATTAAGACATGAATCAGATCCATGTGGCATTCAAAACAAATTTATTTTGGTTATATTCTTTACAAG
TCATAATTTTTACCTAAAATTGTGGAATATGCATGTGAATTACACATGTGTAGTAATAAACTCAACTATTGAATTTTTCCTGTTTCATTT
CTAAATGACTGAACTGATGGTAAACAAATTTAATGAAGTCAGCTACCATGTTGAAAATAAGGATATTAGAACTGATTTCATACAATAGAG
GTGATCTGTGCATTATCCATAACAACGTTTTCTTTCACTATAGGACCACAGACAAATATTTATGTAAATAGGTATTTTTGTGTGATATTT
TGTGGTACATATAACTTTTTTTAGTGTTTCACAGCATTATTATTTCATTTTATTTGTATTGAATAATGTTTTTAGGTCCAAGTAGACTTG
AATTAATGTCATAATTGTCAGTATTATTGAAAATTATGTCAACTGTACTGTTATTCATCTGTCCCATAGTTTAGAACATGACCTGGCTAT
CTGGCATTGTTGCAAGTGCCTTAAATTCATGGCATCCTATTAAAAAAACAAATTTGGTGTTATGCTGCATGACAAAGACAAACACACCTC
AAAATGTTGTCCTTTCTTAGCTTGCTGCGTTTTACAGTTCTTTCTGCTAACAATTTATAAGCCTTTATTATATAATATTGATGAATTACA
GAAATGATGAAGTTGTTCTCTTATTTCTGTTAAATGTACCAGAGCTGTGTATCTGTTAATGAGATACAGCGTCATTTCTGTGAAATGTAT
AAATGTATGTGCAGGTCAAATTAATATATGACATTCTATCAGTCTGTATACAGGTATTCCTGTTTTGCTAAGCTGTGCAGATTCTGTAAA
AATAAATTAGTGCAGTCAAGTTCTAACATATCTCATTTTATAGACTCCATTGACAATGGTCCAACCGAAAAGAAAAATTGGAAATGACTG
CTAACCAGACCTCGTTATGAAACCAATGATGAAAAAGTCACTTGGTGCACCTCTCAACAAAACAGGATGCTTTTTCCGAGTTCTTGTATA
TGCAAATCATTTACGAGGCAAGTTTTCAACAGACCTAGAAAGCAAAACATTGAAAGTGTGTTGTTAGCCCTCCTCTCTGCCCCTGAATCA
ACAGACAGAGCTCTGGGACCTTGGCAATGACTCAGAGGTTGGGGCTTTCTGAGTAAAGGGACATTTCTTTAAGCATCATCTATCAAATTT
ATTTCAATGTATGATGTTTTTACAACTGGTCAGTTCTTTTGTATTCTTACAGCTATGGTTATTTGATTGTCCTCTTACAATTTGTTCTAC
ATGAAAGAGTTCTTTGTTAGTCAGAATGCAACAAACTGTCATCAAATGGTCATTGACCACTTGCACTCTTTTGATGTAGATTAAAAACTT
TTTCATAAATTTACCTGCTTTGATTTGCTCTGTATTTTTCCTGCAGCTGTAATTGCTGAGTGCCTGTTGTATACTTTATAGAGTTGAAAT

>90945_90945_4_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000374064_PRKG1_chr10_53564345_ENST00000373980_length(amino acids)=612AA_BP=123
MEGGGGSGNKTTGGLAGFFGAGGAGYSHADLAGVPLTGMNPLSPYLNVDPRYLVQDTDEFILPTGANKTRGRFELAFFTIGGCCMTALLY
SAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTALVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEE
THYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLD
DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSD
FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKI
GFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNP

--------------------------------------------------------------
>90945_90945_5_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000374064_PRKG1_chr10_53564345_ENST00000373985_length(transcript)=6411nt_BP=492nt
AGGTCAGCGTGTGAAGTAGGCGCTGGCAACGCGGGGTTACCCGCTGTTATTGAGGAGTAACGGCCCAGCGGACCACCCAGGCTTGAGGCA
GCGGCGGGAACCACTCGGTTTGCTGCGATACCATGGAAGGAGGCGGGGGAAGCGGCAACAAAACCACAGGGGGATTGGCCGGCTTTTTCG
GAGCCGGCGGAGCAGGTTACTCGCACGCGGATTTGGCTGGCGTCCCGCTAACTGGTATGAACCCTCTGTCTCCTTATTTAAATGTGGATC
CACGATACCTCGTGCAGGATACAGATGAGTTTATTTTACCTACCGGAGCTAATAAAACCCGGGGCAGATTTGAGCTGGCCTTCTTTACGA
TTGGAGGATGTTGCATGACAGCTTTGCTCTATAGTGCATTTGGTGTCATCATTGAGAAAACACGAGGTGCAGAAGATGACCTTAACACAG
TAGCAGCTGGAACCATGACAGGCATGTTGTATAAATGTACAGCTCTTGTAAATGTAAAACTCTGGGCCATTGATCGACAATGTTTTCAAA
CAATAATGATGAGGACAGGACTCATCAAGCATACCGAGTATATGGAATTTTTAAAAAGCGTTCCAACATTCCAGAGCCTTCCTGAAGAGA
TCCTCAGCAAGCTTGCTGATGTCCTTGAAGAGACCCACTATGAAAATGGAGAATATATTATCAGGCAAGGTGCAAGAGGGGACACCTTCT
TTATCATCAGCAAAGGAACGGTAAATGTCACTCGTGAAGACTCACCGAGTGAAGACCCAGTCTTTCTTAGAACTTTAGGAAAAGGAGACT
GGTTTGGAGAGAAAGCCTTGCAGGGGGAAGATGTGAGAACAGCAAACGTAATTGCTGCAGAAGCTGTAACCTGCCTTGTGATTGACAGAG
ACTCTTTTAAACATTTGATTGGAGGGCTGGATGATGTTTCTAATAAAGCATATGAAGATGCAGAAGCTAAAGCAAAATATGAAGCTGAAG
CGGCTTTCTTCGCCAACCTGAAGCTGTCTGATTTCAACATCATTGATACCCTTGGAGTTGGAGGTTTCGGACGAGTAGAACTGGTCCAGT
TGAAAAGTGAAGAATCCAAAACGTTTGCAATGAAGATTCTCAAGAAACGTCACATTGTGGACACAAGACAGCAGGAGCACATCCGCTCAG
AGAAGCAGATCATGCAGGGGGCTCATTCCGATTTCATAGTGAGACTGTACAGAACATTTAAGGACAGCAAATATTTGTATATGTTGATGG
AAGCTTGTCTAGGTGGAGAGCTCTGGACCATTCTCAGGGATAGAGGTTCGTTTGAAGATTCTACAACCAGATTTTACACAGCATGTGTGG
TAGAAGCTTTTGCCTATCTGCATTCCAAAGGAATCATTTACAGGGACCTCAAGCCAGAAAATCTCATCCTAGATCACCGAGGTTATGCCA
AACTGGTTGATTTTGGCTTTGCAAAGAAAATAGGATTTGGAAAGAAAACATGGACTTTTTGTGGGACTCCAGAGTATGTAGCCCCAGAGA
TCATCCTGAACAAAGGCCATGACATTTCAGCCGACTACTGGTCACTGGGAATCCTAATGTATGAACTCCTGACTGGCAGCCCACCTTTCT
CAGGCCCAGATCCTATGAAAACCTATAACATCATATTGAGGGGGATTGACATGATAGAATTTCCAAAGAAGATTGCCAAAAATGCTGCTA
ATTTAATTAAAAAACTATGCAGGGACAATCCATCAGAAAGATTAGGGAATTTGAAAAATGGAGTAAAAGACATTCAAAAGCACAAATGGT
TTGAGGGCTTTAACTGGGAAGGCTTAAGAAAAGGTACCTTGACACCTCCTATAATACCAAGTGTTGCATCACCCACAGACACAAGTAATT
TTGACAGTTTCCCTGAGGACAACGATGAACCACCACCTGATGACAACTCAGGATGGGATATAGACTTCTAATGTATTTCTCTTACCTGCT
TCTGCCTTGCTGAAGACAGCTTTTTCTGAGACACAGCTGCCAGCAAACCTGAGGGAAAGAGAGAAGATTAGTGCTCGGGGTCACCATGAT
GCCTTTGATCGATGCTGCTCCAGTAACTACAGTGGCATTAGGACTTACCGCTTAGATGACAATAGTGCTCTTTACATGTTTTCTGTTTGA
ACCTAAAATAGCAGTTGACATGGTGGTCCTGAAGCAAAGCCTTTCACCAGTAAAAGATGTTTTCTATTGTTGCAATGACCTTGCTTTGCT
CTGATTATAATTTGAAAGACTGTAGGAAACACTTCAATGTAGTATAAGAGTCTGTACCTTGCTGGAATATTCAAGAAGATGAAAGAATAA
TATATTGGGTACAATAGATTACTATGGTACAGAAACTGGGCTATTCCCTTTCTTCAAGTGAAGGCTGTGGGATCTATTACTGCAGGCCGG
TGTATATACCATACAAAAGAGGACCACACATCTGTTGGTCACAGAGTTCATGTCACACCAGTGCTAGAAGTTTCATGATTTTATTTCCCA
GCAGTGCTGATGACAAGACTGAATGTTACCTTTTCTTTCTGACAGATTTTAAAAATTGATATGATAAAAGCACAACTGCTATAGATTCTG
CTGAGACCTCTCATAGTAGGTATATATGAGTTTTCACAGAAGACTGAAAAATAATGCATGATATTTGTTTGTTTTTTTTGATAAATTGGC
ATGACAGAGTGGGGAAAAAAAGCAATTCACAAAACCATTTCATATTTTTTAAAATATTGTGCTTAAAGATGGTCCTGGAAGTAAATGACT
AGCAGCCAATTGGTTTTACTTAACATACCCTCAAACTGAGGCTTAAAGTATTCCCTTTTATAAAAATAAATGCTTGGGGTAGGGTGGAGT
GGGGAGGGATTAAAACCCATCCAAAAAATAAATAAAAACTATATAGGTGCTATGTATATCTTTCATCTGTAAATGTCAGTGTCTGAACAG
ACAACACAAATTCAAATCATTATACGTGTAGCCAGAAACTCAAGCATTTTCACTAAAGTTATTAAACCAAACTCCTGTCCAATTTCACTT
ATACAACATAGTCAGTCTAGAGTTGAGAGACAAAGGTAATTATAAACCTATTTGAACTAGCTTCTTGTCTTAGGCCTGAACCAAAAAACA
ACAAACAAACAAAAAACAAGAATGAAAAACAGAAATAAAAGAAGTAGAAAAGACAAAGAAAGAAAGCCCAAAGTCAAAGTTGTTAATATT
TACAGGTTTACCAGATCTGGAACATTACTTATTTGAGGTCAGAGAACAAAACAAGAACCTGGCCAGGTGTTGATTACCTTTTAGTGAATA
AGCTGAGTCCATATACTTGTCTAACTAAGAAAGCAGTACAGAGGAAAACAGGAACCTGATTTTTTTAAAATAAATTTTAAATAAAATAGA
ATTACTACAATTCTGCAATTTCATACTACCTAAAAAAGACTAGATTTGAAAATGTCAAGCTGATTTACTTTATTCACATGGAGAAAAGAA
TCCACAAATTAAACTGAGTCCTTCACTGGCATGCCAGTTGACTATTATTAGCTGTCATAAGTAACTCAGCCATTTGGAAGCATTTCCTGG
ACAAAATTACATTATACCTGTGAAGAAAAATATAGAAGCTTTCAAGCTGTCATTCTGTTTTGGCCCTGTGTGAATTTGGTATATTAAATT
GACGCTTGCTTTTTTTTTCAGTAGAGTTTTCTTTTTAATCAATCAAACGCCTACATTTCTGGAAGAAAAAGTCCAATTAGATCATTACAC
CTTAACTAAGAAGGCAAATCTTATAAATTTTGCTTGAATTGTTCTTACTCAAAACTACCTTAGAATATGGTATCTTATGAAAATATAATA
TTCTTAAAATTTTGGAGGATAAAATGAAAAGGGTATAAACTTCAATTAGAACTTTAATCCTAAAATATTGTTATTCTTGTATTTTTGGAG
TTTTCCGTCCCTTACAATTTCTCCAAATTGGTCTATTCCCCAAGATATCCACTGTTTTCTACAGATTTTAGAATATAAAATTAAACATAT
CAACCTAAAATCTAGCTATGAATGTTATTTCAAGAGTTTTATATTTTTAATTGGCTTTTTAAAAATATGTAATTCCAATATTATAGTGAA
TGTTCAGTAACTTTTGTTGAAAGATAATGTGGTTTAGGCTTGCTAAAGAAAGGCTTGCTAGAATACTAAATTTACCTTGTTATTTGGAAA
GAGAATCTGCTCCTATAACGTTTTAAAAATCCCCAAAGTCCCAGAGATTAGCACTTGCTATGGATTTTGGAACTATGGTTCAAGTCTAAG
ACAACCAATATGAATAAGTTCAATGGAGAAGGAAGAAGTAGCATTCAGCACAAGAAACTGTAGATTGTTTCTCCCACTTGTTACTGCATC
TTTGTTCATTTCACCCATAGCATTGCATTTGATGTCTGAAGTAATTACCACAAAATAAAGGTAAACTACATCTTCCAAGATGTACCAACA
GAAAACATTCGTCTAATTTTGTCAACATTGAATTTTTAGGATTTAAATCTTGTCTTAATGAAGACTCTAGGGCTAAAATTCATGGTCAGT
TCCATAAAATGCATCTCACTTTATTTCTGAATTTTTCACAACCCCTCTATTTTCTTACATTAAAGAACATCTGGATAAGTTAGAATAGTG
CCAACTTGTTTGATTTGTTATATGATTTTCTTGTTAATGTGTTGAGTATGGGAAATAAGGGCTTTCTGTGTGTCTTGACTCACAGGAAAA
CTGAAACTGCCAAGGGAAGCAACATTAAAACAACTGGGATAGATTGAATACATTTGAAAAAATAATTTCTGGAAAAACGCTATACATGCT
TTTTATGTTTATATCTTCTTTCTTATTAAGACATGAATCAGATCCATGTGGCATTCAAAACAAATTTATTTTGGTTATATTCTTTACAAG
TCATAATTTTTACCTAAAATTGTGGAATATGCATGTGAATTACACATGTGTAGTAATAAACTCAACTATTGAATTTTTCCTGTTTCATTT
CTAAATGACTGAACTGATGGTAAACAAATTTAATGAAGTCAGCTACCATGTTGAAAATAAGGATATTAGAACTGATTTCATACAATAGAG
GTGATCTGTGCATTATCCATAACAACGTTTTCTTTCACTATAGGACCACAGACAAATATTTATGTAAATAGGTATTTTTGTGTGATATTT
TGTGGTACATATAACTTTTTTTAGTGTTTCACAGCATTATTATTTCATTTTATTTGTATTGAATAATGTTTTTAGGTCCAAGTAGACTTG
AATTAATGTCATAATTGTCAGTATTATTGAAAATTATGTCAACTGTACTGTTATTCATCTGTCCCATAGTTTAGAACATGACCTGGCTAT
CTGGCATTGTTGCAAGTGCCTTAAATTCATGGCATCCTATTAAAAAAACAAATTTGGTGTTATGCTGCATGACAAAGACAAACACACCTC
AAAATGTTGTCCTTTCTTAGCTTGCTGCGTTTTACAGTTCTTTCTGCTAACAATTTATAAGCCTTTATTATATAATATTGATGAATTACA
GAAATGATGAAGTTGTTCTCTTATTTCTGTTAAATGTACCAGAGCTGTGTATCTGTTAATGAGATACAGCGTCATTTCTGTGAAATGTAT
AAATGTATGTGCAGGTCAAATTAATATATGACATTCTATCAGTCTGTATACAGGTATTCCTGTTTTGCTAAGCTGTGCAGATTCTGTAAA
AATAAATTAGTGCAGTCAAGTTCTAACATATCTCATTTTATAGACTCCATTGACAATGGTCCAACCGAAAAGAAAAATTGGAAATGACTG
CTAACCAGACCTCGTTATGAAACCAATGATGAAAAAGTCACTTGGTGCACCTCTCAACAAAACAGGATGCTTTTTCCGAGTTCTTGTATA
TGCAAATCATTTACGAGGCAAGTTTTCAACAGACCTAGAAAGCAAAACATTGAAAGTGTGTTGTTAGCCCTCCTCTCTGCCCCTGAATCA
ACAGACAGAGCTCTGGGACCTTGGCAATGACTCAGAGGTTGGGGCTTTCTGAGTAAAGGGACATTTCTTTAAGCATCATCTATCAAATTT
ATTTCAATGTATGATGTTTTTACAACTGGTCAGTTCTTTTGTATTCTTACAGCTATGGTTATTTGATTGTCCTCTTACAATTTGTTCTAC
ATGAAAGAGTTCTTTGTTAGTCAGAATGCAACAAACTGTCATCAAATGGTCATTGACCACTTGCACTCTTTTGATGTAGATTAAAAACTT
TTTCATAAATTTACCTGCTTTGATTTGCTCTGTATTTTTCCTGCAGCTGTAATTGCTGAGTGCCTGTTGTATACTTTATAGAGTTGAAAT

>90945_90945_5_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000374064_PRKG1_chr10_53564345_ENST00000373985_length(amino acids)=612AA_BP=123
MEGGGGSGNKTTGGLAGFFGAGGAGYSHADLAGVPLTGMNPLSPYLNVDPRYLVQDTDEFILPTGANKTRGRFELAFFTIGGCCMTALLY
SAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTALVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEE
THYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLD
DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSD
FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKI
GFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNP

--------------------------------------------------------------
>90945_90945_6_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000374064_PRKG1_chr10_53564345_ENST00000401604_length(transcript)=3575nt_BP=492nt
AGGTCAGCGTGTGAAGTAGGCGCTGGCAACGCGGGGTTACCCGCTGTTATTGAGGAGTAACGGCCCAGCGGACCACCCAGGCTTGAGGCA
GCGGCGGGAACCACTCGGTTTGCTGCGATACCATGGAAGGAGGCGGGGGAAGCGGCAACAAAACCACAGGGGGATTGGCCGGCTTTTTCG
GAGCCGGCGGAGCAGGTTACTCGCACGCGGATTTGGCTGGCGTCCCGCTAACTGGTATGAACCCTCTGTCTCCTTATTTAAATGTGGATC
CACGATACCTCGTGCAGGATACAGATGAGTTTATTTTACCTACCGGAGCTAATAAAACCCGGGGCAGATTTGAGCTGGCCTTCTTTACGA
TTGGAGGATGTTGCATGACAGCTTTGCTCTATAGTGCATTTGGTGTCATCATTGAGAAAACACGAGGTGCAGAAGATGACCTTAACACAG
TAGCAGCTGGAACCATGACAGGCATGTTGTATAAATGTACAGCTCTTGTAAATGTAAAACTCTGGGCCATTGATCGACAATGTTTTCAAA
CAATAATGATGAGGACAGGACTCATCAAGCATACCGAGTATATGGAATTTTTAAAAAGCGTTCCAACATTCCAGAGCCTTCCTGAAGAGA
TCCTCAGCAAGCTTGCTGATGTCCTTGAAGAGACCCACTATGAAAATGGAGAATATATTATCAGGCAAGGTGCAAGAGGGGACACCTTCT
TTATCATCAGCAAAGGAACGGTAAATGTCACTCGTGAAGACTCACCGAGTGAAGACCCAGTCTTTCTTAGAACTTTAGGAAAAGGAGACT
GGTTTGGAGAGAAAGCCTTGCAGGGGGAAGATGTGAGAACAGCAAACGTAATTGCTGCAGAAGCTGTAACCTGCCTTGTGATTGACAGAG
ACTCTTTTAAACATTTGATTGGAGGGCTGGATGATGTTTCTAATAAAGCATATGAAGATGCAGAAGCTAAAGCAAAATATGAAGCTGAAG
CGGCTTTCTTCGCCAACCTGAAGCTGTCTGATTTCAACATCATTGATACCCTTGGAGTTGGAGGTTTCGGACGAGTAGAACTGGTCCAGT
TGAAAAGTGAAGAATCCAAAACGTTTGCAATGAAGATTCTCAAGAAACGTCACATTGTGGACACAAGACAGCAGGAGCACATCCGCTCAG
AGAAGCAGATCATGCAGGGGGCTCATTCCGATTTCATAGTGAGACTGTACAGAACATTTAAGGACAGCAAATATTTGTATATGTTGATGG
AAGCTTGTCTAGGTGGAGAGCTCTGGACCATTCTCAGGGATAGAGGTTCGTTTGAAGATTCTACAACCAGATTTTACACAGCATGTGTGG
TAGAAGCTTTTGCCTATCTGCATTCCAAAGGAATCATTTACAGGGACCTCAAGCCAGAAAATCTCATCCTAGATCACCGAGGTTATGCCA
AACTGGTTGATTTTGGCTTTGCAAAGAAAATAGGATTTGGAAAGAAAACATGGACTTTTTGTGGGACTCCAGAGTATGTAGCCCCAGAGA
TCATCCTGAACAAAGGCCATGACATTTCAGCCGACTACTGGTCACTGGGAATCCTAATGTATGAACTCCTGACTGGCAGCCCACCTTTCT
CAGGCCCAGATCCTATGAAAACCTATAACATCATATTGAGGGGGATTGACATGATAGAATTTCCAAAGAAGATTGCCAAAAATGCTGCTA
ATTTAATTAAAAAACTATGCAGGGACAATCCATCAGAAAGATTAGGGAATTTGAAAAATGGAGTAAAAGACATTCAAAAGCACAAATGGT
TTGAGGGCTTTAACTGGGAAGGCTTAAGAAAAGGTACCTTGACACCTCCTATAATACCAAGTGTTGCATCACCCACAGACACAAGTAATT
TTGACAGTTTCCCTGAGGACAACGATGAACCACCACCTGATGACAACTCAGGATGGGATATAGACTTCTAATGTATTTCTCTTACCTGCT
TCTGCCTTGCTGAAGACAGCTTTTTCTGAGACACAGCTGCCAGCAAACCTGAGGGAAAGAGAGAAGATTAGTGCTCGGGGTCACCATGAT
GCCTTTGATCGATGCTGCTCCAGTAACTACAGTGGCATTAGGACTTACCGCTTAGATGACAATAGTGCTCTTTACATGTTTTCTGTTTGA
ACCTAAAATAGCAGTTGACATGGTGGTCCTGAAGCAAAGCCTTTCACCAGTAAAAGATGTTTTCTATTGTTGCAATGACCTTGCTTTGCT
CTGATTATAATTTGAAAGACTGTAGGAAACACTTCAATGTAGTATAAGAGTCTGTACCTTGCTGGAATATTCAAGAAGATGAAAGAATAA
TATATTGGGTACAATAGATTACTATGGTACAGAAACTGGGCTATTCCCTTTCTTCAAGTGAAGGCTGTGGGATCTATTACTGCAGGCCGG
TGTATATACCATACAAAAGAGGACCACACATCTGTTGGTCACAGAGTTCATGTCACACCAGTGCTAGAAGTTTCATGATTTTATTTCCCA
GCAGTGCTGATGACAAGACTGAATGTTACCTTTTCTTTCTGACAGATTTTAAAAATTGATATGATAAAAGCACAACTGCTATAGATTCTG
CTGAGACCTCTCATAGTAGGTATATATGAGTTTTCACAGAAGACTGAAAAATAATGCATGATATTTGTTTGTTTTTTTTGATAAATTGGC
ATGACAGAGTGGGGAAAAAAAGCAATTCACAAAACCATTTCATATTTTTTAAAATATTGTGCTTAAAGATGGTCCTGGAAGTAAATGACT
AGCAGCCAATTGGTTTTACTTAACATACCCTCAAACTGAGGCTTAAAGTATTCCCTTTTATAAAAATAAATGCTTGGGGTAGGGTGGAGT
GGGGAGGGATTAAAACCCATCCAAAAAATAAATAAAAACTATATAGGTGCTATGTATATCTTTCATCTGTAAATGTCAGTGTCTGAACAG
ACAACACAAATTCAAATCATTATACGTGTAGCCAGAAACTCAAGCATTTTCACTAAAGTTATTAAACCAAACTCCTGTCCAATTTCACTT
ATACAACATAGTCAGTCTAGAGTTGAGAGACAAAGGTAATTATAAACCTATTTGAACTAGCTTCTTGTCTTAGGCCTGAACCAAAAAACA
ACAAACAAACAAAAAACAAGAATGAAAAACAGAAATAAAAGAAGTAGAAAAGACAAAGAAAGAAAGCCCAAAGTCAAAGTTGTTAATATT
TACAGGTTTACCAGATCTGGAACATTACTTATTTGAGGTCAGAGAACAAAACAAGAACCTGGCCAGGTGTTGATTACCTTTTAGTGAATA
AGCTGAGTCCATATACTTGTCTAACTAAGAAAGCAGTACAGAGGAAAACAGGAACCTGATTTTTTTAAAATAAATTTTAAATAAAATAGA
ATTACTACAATTCTGCAATTTCATACTACCTAAAAAAGACTAGATTTGAAAATGTCAAGCTGATTTACTTTATTCACATGGAGAAAAGAA

>90945_90945_6_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000374064_PRKG1_chr10_53564345_ENST00000401604_length(amino acids)=612AA_BP=123
MEGGGGSGNKTTGGLAGFFGAGGAGYSHADLAGVPLTGMNPLSPYLNVDPRYLVQDTDEFILPTGANKTRGRFELAFFTIGGCCMTALLY
SAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTALVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEE
THYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLD
DVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSD
FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKI
GFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNP

--------------------------------------------------------------
>90945_90945_7_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000374065_PRKG1_chr10_53564345_ENST00000373980_length(transcript)=6427nt_BP=508nt
AGGCGCTGGCAACGCGGGGTTACCCGCTGTTATTGAGGAGTAACGGCCCAGCGGACCACCCAGGCTTGAGGCAGCGGCGGGAACCACTCG
GTTTGCTGCGATACCATGGAAGGAGGCGGGGGAAGCGGCAACAAAACCACAGGGGGATTGGCCGGCTTTTTCGGAGCCGGCGGAGCAGGT
TACTCGCACGCGGATTTGGCTGGCGTCCCGCTAACTGGTATGAACCCTCTGTCTCCTTATTTAAATGTGGATCCACGATACCTCGTGCAG
GATACAGATGAGTTTATTTTACCTACCGGAGCTAATAAAACCCGGGGCAGATTTGAGCTGGCCTTCTTTACGATTGGAGGATGTTGCATG
ACAGGGGCACTTTGGGCTAATACTCTAGGTTCTCTGGCTTTGCTCTATAGTGCATTTGGTGTCATCATTGAGAAAACACGAGGTGCAGAA
GATGACCTTAACACAGTAGCAGCTGGAACCATGACAGGCATGTTGTATAAATGTACAGCTCTTGTAAATGTAAAACTCTGGGCCATTGAT
CGACAATGTTTTCAAACAATAATGATGAGGACAGGACTCATCAAGCATACCGAGTATATGGAATTTTTAAAAAGCGTTCCAACATTCCAG
AGCCTTCCTGAAGAGATCCTCAGCAAGCTTGCTGATGTCCTTGAAGAGACCCACTATGAAAATGGAGAATATATTATCAGGCAAGGTGCA
AGAGGGGACACCTTCTTTATCATCAGCAAAGGAACGGTAAATGTCACTCGTGAAGACTCACCGAGTGAAGACCCAGTCTTTCTTAGAACT
TTAGGAAAAGGAGACTGGTTTGGAGAGAAAGCCTTGCAGGGGGAAGATGTGAGAACAGCAAACGTAATTGCTGCAGAAGCTGTAACCTGC
CTTGTGATTGACAGAGACTCTTTTAAACATTTGATTGGAGGGCTGGATGATGTTTCTAATAAAGCATATGAAGATGCAGAAGCTAAAGCA
AAATATGAAGCTGAAGCGGCTTTCTTCGCCAACCTGAAGCTGTCTGATTTCAACATCATTGATACCCTTGGAGTTGGAGGTTTCGGACGA
GTAGAACTGGTCCAGTTGAAAAGTGAAGAATCCAAAACGTTTGCAATGAAGATTCTCAAGAAACGTCACATTGTGGACACAAGACAGCAG
GAGCACATCCGCTCAGAGAAGCAGATCATGCAGGGGGCTCATTCCGATTTCATAGTGAGACTGTACAGAACATTTAAGGACAGCAAATAT
TTGTATATGTTGATGGAAGCTTGTCTAGGTGGAGAGCTCTGGACCATTCTCAGGGATAGAGGTTCGTTTGAAGATTCTACAACCAGATTT
TACACAGCATGTGTGGTAGAAGCTTTTGCCTATCTGCATTCCAAAGGAATCATTTACAGGGACCTCAAGCCAGAAAATCTCATCCTAGAT
CACCGAGGTTATGCCAAACTGGTTGATTTTGGCTTTGCAAAGAAAATAGGATTTGGAAAGAAAACATGGACTTTTTGTGGGACTCCAGAG
TATGTAGCCCCAGAGATCATCCTGAACAAAGGCCATGACATTTCAGCCGACTACTGGTCACTGGGAATCCTAATGTATGAACTCCTGACT
GGCAGCCCACCTTTCTCAGGCCCAGATCCTATGAAAACCTATAACATCATATTGAGGGGGATTGACATGATAGAATTTCCAAAGAAGATT
GCCAAAAATGCTGCTAATTTAATTAAAAAACTATGCAGGGACAATCCATCAGAAAGATTAGGGAATTTGAAAAATGGAGTAAAAGACATT
CAAAAGCACAAATGGTTTGAGGGCTTTAACTGGGAAGGCTTAAGAAAAGGTACCTTGACACCTCCTATAATACCAAGTGTTGCATCACCC
ACAGACACAAGTAATTTTGACAGTTTCCCTGAGGACAACGATGAACCACCACCTGATGACAACTCAGGATGGGATATAGACTTCTAATGT
ATTTCTCTTACCTGCTTCTGCCTTGCTGAAGACAGCTTTTTCTGAGACACAGCTGCCAGCAAACCTGAGGGAAAGAGAGAAGATTAGTGC
TCGGGGTCACCATGATGCCTTTGATCGATGCTGCTCCAGTAACTACAGTGGCATTAGGACTTACCGCTTAGATGACAATAGTGCTCTTTA
CATGTTTTCTGTTTGAACCTAAAATAGCAGTTGACATGGTGGTCCTGAAGCAAAGCCTTTCACCAGTAAAAGATGTTTTCTATTGTTGCA
ATGACCTTGCTTTGCTCTGATTATAATTTGAAAGACTGTAGGAAACACTTCAATGTAGTATAAGAGTCTGTACCTTGCTGGAATATTCAA
GAAGATGAAAGAATAATATATTGGGTACAATAGATTACTATGGTACAGAAACTGGGCTATTCCCTTTCTTCAAGTGAAGGCTGTGGGATC
TATTACTGCAGGCCGGTGTATATACCATACAAAAGAGGACCACACATCTGTTGGTCACAGAGTTCATGTCACACCAGTGCTAGAAGTTTC
ATGATTTTATTTCCCAGCAGTGCTGATGACAAGACTGAATGTTACCTTTTCTTTCTGACAGATTTTAAAAATTGATATGATAAAAGCACA
ACTGCTATAGATTCTGCTGAGACCTCTCATAGTAGGTATATATGAGTTTTCACAGAAGACTGAAAAATAATGCATGATATTTGTTTGTTT
TTTTTGATAAATTGGCATGACAGAGTGGGGAAAAAAAGCAATTCACAAAACCATTTCATATTTTTTAAAATATTGTGCTTAAAGATGGTC
CTGGAAGTAAATGACTAGCAGCCAATTGGTTTTACTTAACATACCCTCAAACTGAGGCTTAAAGTATTCCCTTTTATAAAAATAAATGCT
TGGGGTAGGGTGGAGTGGGGAGGGATTAAAACCCATCCAAAAAATAAATAAAAACTATATAGGTGCTATGTATATCTTTCATCTGTAAAT
GTCAGTGTCTGAACAGACAACACAAATTCAAATCATTATACGTGTAGCCAGAAACTCAAGCATTTTCACTAAAGTTATTAAACCAAACTC
CTGTCCAATTTCACTTATACAACATAGTCAGTCTAGAGTTGAGAGACAAAGGTAATTATAAACCTATTTGAACTAGCTTCTTGTCTTAGG
CCTGAACCAAAAAACAACAAACAAACAAAAAACAAGAATGAAAAACAGAAATAAAAGAAGTAGAAAAGACAAAGAAAGAAAGCCCAAAGT
CAAAGTTGTTAATATTTACAGGTTTACCAGATCTGGAACATTACTTATTTGAGGTCAGAGAACAAAACAAGAACCTGGCCAGGTGTTGAT
TACCTTTTAGTGAATAAGCTGAGTCCATATACTTGTCTAACTAAGAAAGCAGTACAGAGGAAAACAGGAACCTGATTTTTTTAAAATAAA
TTTTAAATAAAATAGAATTACTACAATTCTGCAATTTCATACTACCTAAAAAAGACTAGATTTGAAAATGTCAAGCTGATTTACTTTATT
CACATGGAGAAAAGAATCCACAAATTAAACTGAGTCCTTCACTGGCATGCCAGTTGACTATTATTAGCTGTCATAAGTAACTCAGCCATT
TGGAAGCATTTCCTGGACAAAATTACATTATACCTGTGAAGAAAAATATAGAAGCTTTCAAGCTGTCATTCTGTTTTGGCCCTGTGTGAA
TTTGGTATATTAAATTGACGCTTGCTTTTTTTTTCAGTAGAGTTTTCTTTTTAATCAATCAAACGCCTACATTTCTGGAAGAAAAAGTCC
AATTAGATCATTACACCTTAACTAAGAAGGCAAATCTTATAAATTTTGCTTGAATTGTTCTTACTCAAAACTACCTTAGAATATGGTATC
TTATGAAAATATAATATTCTTAAAATTTTGGAGGATAAAATGAAAAGGGTATAAACTTCAATTAGAACTTTAATCCTAAAATATTGTTAT
TCTTGTATTTTTGGAGTTTTCCGTCCCTTACAATTTCTCCAAATTGGTCTATTCCCCAAGATATCCACTGTTTTCTACAGATTTTAGAAT
ATAAAATTAAACATATCAACCTAAAATCTAGCTATGAATGTTATTTCAAGAGTTTTATATTTTTAATTGGCTTTTTAAAAATATGTAATT
CCAATATTATAGTGAATGTTCAGTAACTTTTGTTGAAAGATAATGTGGTTTAGGCTTGCTAAAGAAAGGCTTGCTAGAATACTAAATTTA
CCTTGTTATTTGGAAAGAGAATCTGCTCCTATAACGTTTTAAAAATCCCCAAAGTCCCAGAGATTAGCACTTGCTATGGATTTTGGAACT
ATGGTTCAAGTCTAAGACAACCAATATGAATAAGTTCAATGGAGAAGGAAGAAGTAGCATTCAGCACAAGAAACTGTAGATTGTTTCTCC
CACTTGTTACTGCATCTTTGTTCATTTCACCCATAGCATTGCATTTGATGTCTGAAGTAATTACCACAAAATAAAGGTAAACTACATCTT
CCAAGATGTACCAACAGAAAACATTCGTCTAATTTTGTCAACATTGAATTTTTAGGATTTAAATCTTGTCTTAATGAAGACTCTAGGGCT
AAAATTCATGGTCAGTTCCATAAAATGCATCTCACTTTATTTCTGAATTTTTCACAACCCCTCTATTTTCTTACATTAAAGAACATCTGG
ATAAGTTAGAATAGTGCCAACTTGTTTGATTTGTTATATGATTTTCTTGTTAATGTGTTGAGTATGGGAAATAAGGGCTTTCTGTGTGTC
TTGACTCACAGGAAAACTGAAACTGCCAAGGGAAGCAACATTAAAACAACTGGGATAGATTGAATACATTTGAAAAAATAATTTCTGGAA
AAACGCTATACATGCTTTTTATGTTTATATCTTCTTTCTTATTAAGACATGAATCAGATCCATGTGGCATTCAAAACAAATTTATTTTGG
TTATATTCTTTACAAGTCATAATTTTTACCTAAAATTGTGGAATATGCATGTGAATTACACATGTGTAGTAATAAACTCAACTATTGAAT
TTTTCCTGTTTCATTTCTAAATGACTGAACTGATGGTAAACAAATTTAATGAAGTCAGCTACCATGTTGAAAATAAGGATATTAGAACTG
ATTTCATACAATAGAGGTGATCTGTGCATTATCCATAACAACGTTTTCTTTCACTATAGGACCACAGACAAATATTTATGTAAATAGGTA
TTTTTGTGTGATATTTTGTGGTACATATAACTTTTTTTAGTGTTTCACAGCATTATTATTTCATTTTATTTGTATTGAATAATGTTTTTA
GGTCCAAGTAGACTTGAATTAATGTCATAATTGTCAGTATTATTGAAAATTATGTCAACTGTACTGTTATTCATCTGTCCCATAGTTTAG
AACATGACCTGGCTATCTGGCATTGTTGCAAGTGCCTTAAATTCATGGCATCCTATTAAAAAAACAAATTTGGTGTTATGCTGCATGACA
AAGACAAACACACCTCAAAATGTTGTCCTTTCTTAGCTTGCTGCGTTTTACAGTTCTTTCTGCTAACAATTTATAAGCCTTTATTATATA
ATATTGATGAATTACAGAAATGATGAAGTTGTTCTCTTATTTCTGTTAAATGTACCAGAGCTGTGTATCTGTTAATGAGATACAGCGTCA
TTTCTGTGAAATGTATAAATGTATGTGCAGGTCAAATTAATATATGACATTCTATCAGTCTGTATACAGGTATTCCTGTTTTGCTAAGCT
GTGCAGATTCTGTAAAAATAAATTAGTGCAGTCAAGTTCTAACATATCTCATTTTATAGACTCCATTGACAATGGTCCAACCGAAAAGAA
AAATTGGAAATGACTGCTAACCAGACCTCGTTATGAAACCAATGATGAAAAAGTCACTTGGTGCACCTCTCAACAAAACAGGATGCTTTT
TCCGAGTTCTTGTATATGCAAATCATTTACGAGGCAAGTTTTCAACAGACCTAGAAAGCAAAACATTGAAAGTGTGTTGTTAGCCCTCCT
CTCTGCCCCTGAATCAACAGACAGAGCTCTGGGACCTTGGCAATGACTCAGAGGTTGGGGCTTTCTGAGTAAAGGGACATTTCTTTAAGC
ATCATCTATCAAATTTATTTCAATGTATGATGTTTTTACAACTGGTCAGTTCTTTTGTATTCTTACAGCTATGGTTATTTGATTGTCCTC
TTACAATTTGTTCTACATGAAAGAGTTCTTTGTTAGTCAGAATGCAACAAACTGTCATCAAATGGTCATTGACCACTTGCACTCTTTTGA
TGTAGATTAAAAACTTTTTCATAAATTTACCTGCTTTGATTTGCTCTGTATTTTTCCTGCAGCTGTAATTGCTGAGTGCCTGTTGTATAC

>90945_90945_7_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000374065_PRKG1_chr10_53564345_ENST00000373980_length(amino acids)=623AA_BP=134
MEGGGGSGNKTTGGLAGFFGAGGAGYSHADLAGVPLTGMNPLSPYLNVDPRYLVQDTDEFILPTGANKTRGRFELAFFTIGGCCMTGALW
ANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTALVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE
ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDR
DSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRS
EKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYA
KLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAA

--------------------------------------------------------------
>90945_90945_8_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000374065_PRKG1_chr10_53564345_ENST00000373985_length(transcript)=6427nt_BP=508nt
AGGCGCTGGCAACGCGGGGTTACCCGCTGTTATTGAGGAGTAACGGCCCAGCGGACCACCCAGGCTTGAGGCAGCGGCGGGAACCACTCG
GTTTGCTGCGATACCATGGAAGGAGGCGGGGGAAGCGGCAACAAAACCACAGGGGGATTGGCCGGCTTTTTCGGAGCCGGCGGAGCAGGT
TACTCGCACGCGGATTTGGCTGGCGTCCCGCTAACTGGTATGAACCCTCTGTCTCCTTATTTAAATGTGGATCCACGATACCTCGTGCAG
GATACAGATGAGTTTATTTTACCTACCGGAGCTAATAAAACCCGGGGCAGATTTGAGCTGGCCTTCTTTACGATTGGAGGATGTTGCATG
ACAGGGGCACTTTGGGCTAATACTCTAGGTTCTCTGGCTTTGCTCTATAGTGCATTTGGTGTCATCATTGAGAAAACACGAGGTGCAGAA
GATGACCTTAACACAGTAGCAGCTGGAACCATGACAGGCATGTTGTATAAATGTACAGCTCTTGTAAATGTAAAACTCTGGGCCATTGAT
CGACAATGTTTTCAAACAATAATGATGAGGACAGGACTCATCAAGCATACCGAGTATATGGAATTTTTAAAAAGCGTTCCAACATTCCAG
AGCCTTCCTGAAGAGATCCTCAGCAAGCTTGCTGATGTCCTTGAAGAGACCCACTATGAAAATGGAGAATATATTATCAGGCAAGGTGCA
AGAGGGGACACCTTCTTTATCATCAGCAAAGGAACGGTAAATGTCACTCGTGAAGACTCACCGAGTGAAGACCCAGTCTTTCTTAGAACT
TTAGGAAAAGGAGACTGGTTTGGAGAGAAAGCCTTGCAGGGGGAAGATGTGAGAACAGCAAACGTAATTGCTGCAGAAGCTGTAACCTGC
CTTGTGATTGACAGAGACTCTTTTAAACATTTGATTGGAGGGCTGGATGATGTTTCTAATAAAGCATATGAAGATGCAGAAGCTAAAGCA
AAATATGAAGCTGAAGCGGCTTTCTTCGCCAACCTGAAGCTGTCTGATTTCAACATCATTGATACCCTTGGAGTTGGAGGTTTCGGACGA
GTAGAACTGGTCCAGTTGAAAAGTGAAGAATCCAAAACGTTTGCAATGAAGATTCTCAAGAAACGTCACATTGTGGACACAAGACAGCAG
GAGCACATCCGCTCAGAGAAGCAGATCATGCAGGGGGCTCATTCCGATTTCATAGTGAGACTGTACAGAACATTTAAGGACAGCAAATAT
TTGTATATGTTGATGGAAGCTTGTCTAGGTGGAGAGCTCTGGACCATTCTCAGGGATAGAGGTTCGTTTGAAGATTCTACAACCAGATTT
TACACAGCATGTGTGGTAGAAGCTTTTGCCTATCTGCATTCCAAAGGAATCATTTACAGGGACCTCAAGCCAGAAAATCTCATCCTAGAT
CACCGAGGTTATGCCAAACTGGTTGATTTTGGCTTTGCAAAGAAAATAGGATTTGGAAAGAAAACATGGACTTTTTGTGGGACTCCAGAG
TATGTAGCCCCAGAGATCATCCTGAACAAAGGCCATGACATTTCAGCCGACTACTGGTCACTGGGAATCCTAATGTATGAACTCCTGACT
GGCAGCCCACCTTTCTCAGGCCCAGATCCTATGAAAACCTATAACATCATATTGAGGGGGATTGACATGATAGAATTTCCAAAGAAGATT
GCCAAAAATGCTGCTAATTTAATTAAAAAACTATGCAGGGACAATCCATCAGAAAGATTAGGGAATTTGAAAAATGGAGTAAAAGACATT
CAAAAGCACAAATGGTTTGAGGGCTTTAACTGGGAAGGCTTAAGAAAAGGTACCTTGACACCTCCTATAATACCAAGTGTTGCATCACCC
ACAGACACAAGTAATTTTGACAGTTTCCCTGAGGACAACGATGAACCACCACCTGATGACAACTCAGGATGGGATATAGACTTCTAATGT
ATTTCTCTTACCTGCTTCTGCCTTGCTGAAGACAGCTTTTTCTGAGACACAGCTGCCAGCAAACCTGAGGGAAAGAGAGAAGATTAGTGC
TCGGGGTCACCATGATGCCTTTGATCGATGCTGCTCCAGTAACTACAGTGGCATTAGGACTTACCGCTTAGATGACAATAGTGCTCTTTA
CATGTTTTCTGTTTGAACCTAAAATAGCAGTTGACATGGTGGTCCTGAAGCAAAGCCTTTCACCAGTAAAAGATGTTTTCTATTGTTGCA
ATGACCTTGCTTTGCTCTGATTATAATTTGAAAGACTGTAGGAAACACTTCAATGTAGTATAAGAGTCTGTACCTTGCTGGAATATTCAA
GAAGATGAAAGAATAATATATTGGGTACAATAGATTACTATGGTACAGAAACTGGGCTATTCCCTTTCTTCAAGTGAAGGCTGTGGGATC
TATTACTGCAGGCCGGTGTATATACCATACAAAAGAGGACCACACATCTGTTGGTCACAGAGTTCATGTCACACCAGTGCTAGAAGTTTC
ATGATTTTATTTCCCAGCAGTGCTGATGACAAGACTGAATGTTACCTTTTCTTTCTGACAGATTTTAAAAATTGATATGATAAAAGCACA
ACTGCTATAGATTCTGCTGAGACCTCTCATAGTAGGTATATATGAGTTTTCACAGAAGACTGAAAAATAATGCATGATATTTGTTTGTTT
TTTTTGATAAATTGGCATGACAGAGTGGGGAAAAAAAGCAATTCACAAAACCATTTCATATTTTTTAAAATATTGTGCTTAAAGATGGTC
CTGGAAGTAAATGACTAGCAGCCAATTGGTTTTACTTAACATACCCTCAAACTGAGGCTTAAAGTATTCCCTTTTATAAAAATAAATGCT
TGGGGTAGGGTGGAGTGGGGAGGGATTAAAACCCATCCAAAAAATAAATAAAAACTATATAGGTGCTATGTATATCTTTCATCTGTAAAT
GTCAGTGTCTGAACAGACAACACAAATTCAAATCATTATACGTGTAGCCAGAAACTCAAGCATTTTCACTAAAGTTATTAAACCAAACTC
CTGTCCAATTTCACTTATACAACATAGTCAGTCTAGAGTTGAGAGACAAAGGTAATTATAAACCTATTTGAACTAGCTTCTTGTCTTAGG
CCTGAACCAAAAAACAACAAACAAACAAAAAACAAGAATGAAAAACAGAAATAAAAGAAGTAGAAAAGACAAAGAAAGAAAGCCCAAAGT
CAAAGTTGTTAATATTTACAGGTTTACCAGATCTGGAACATTACTTATTTGAGGTCAGAGAACAAAACAAGAACCTGGCCAGGTGTTGAT
TACCTTTTAGTGAATAAGCTGAGTCCATATACTTGTCTAACTAAGAAAGCAGTACAGAGGAAAACAGGAACCTGATTTTTTTAAAATAAA
TTTTAAATAAAATAGAATTACTACAATTCTGCAATTTCATACTACCTAAAAAAGACTAGATTTGAAAATGTCAAGCTGATTTACTTTATT
CACATGGAGAAAAGAATCCACAAATTAAACTGAGTCCTTCACTGGCATGCCAGTTGACTATTATTAGCTGTCATAAGTAACTCAGCCATT
TGGAAGCATTTCCTGGACAAAATTACATTATACCTGTGAAGAAAAATATAGAAGCTTTCAAGCTGTCATTCTGTTTTGGCCCTGTGTGAA
TTTGGTATATTAAATTGACGCTTGCTTTTTTTTTCAGTAGAGTTTTCTTTTTAATCAATCAAACGCCTACATTTCTGGAAGAAAAAGTCC
AATTAGATCATTACACCTTAACTAAGAAGGCAAATCTTATAAATTTTGCTTGAATTGTTCTTACTCAAAACTACCTTAGAATATGGTATC
TTATGAAAATATAATATTCTTAAAATTTTGGAGGATAAAATGAAAAGGGTATAAACTTCAATTAGAACTTTAATCCTAAAATATTGTTAT
TCTTGTATTTTTGGAGTTTTCCGTCCCTTACAATTTCTCCAAATTGGTCTATTCCCCAAGATATCCACTGTTTTCTACAGATTTTAGAAT
ATAAAATTAAACATATCAACCTAAAATCTAGCTATGAATGTTATTTCAAGAGTTTTATATTTTTAATTGGCTTTTTAAAAATATGTAATT
CCAATATTATAGTGAATGTTCAGTAACTTTTGTTGAAAGATAATGTGGTTTAGGCTTGCTAAAGAAAGGCTTGCTAGAATACTAAATTTA
CCTTGTTATTTGGAAAGAGAATCTGCTCCTATAACGTTTTAAAAATCCCCAAAGTCCCAGAGATTAGCACTTGCTATGGATTTTGGAACT
ATGGTTCAAGTCTAAGACAACCAATATGAATAAGTTCAATGGAGAAGGAAGAAGTAGCATTCAGCACAAGAAACTGTAGATTGTTTCTCC
CACTTGTTACTGCATCTTTGTTCATTTCACCCATAGCATTGCATTTGATGTCTGAAGTAATTACCACAAAATAAAGGTAAACTACATCTT
CCAAGATGTACCAACAGAAAACATTCGTCTAATTTTGTCAACATTGAATTTTTAGGATTTAAATCTTGTCTTAATGAAGACTCTAGGGCT
AAAATTCATGGTCAGTTCCATAAAATGCATCTCACTTTATTTCTGAATTTTTCACAACCCCTCTATTTTCTTACATTAAAGAACATCTGG
ATAAGTTAGAATAGTGCCAACTTGTTTGATTTGTTATATGATTTTCTTGTTAATGTGTTGAGTATGGGAAATAAGGGCTTTCTGTGTGTC
TTGACTCACAGGAAAACTGAAACTGCCAAGGGAAGCAACATTAAAACAACTGGGATAGATTGAATACATTTGAAAAAATAATTTCTGGAA
AAACGCTATACATGCTTTTTATGTTTATATCTTCTTTCTTATTAAGACATGAATCAGATCCATGTGGCATTCAAAACAAATTTATTTTGG
TTATATTCTTTACAAGTCATAATTTTTACCTAAAATTGTGGAATATGCATGTGAATTACACATGTGTAGTAATAAACTCAACTATTGAAT
TTTTCCTGTTTCATTTCTAAATGACTGAACTGATGGTAAACAAATTTAATGAAGTCAGCTACCATGTTGAAAATAAGGATATTAGAACTG
ATTTCATACAATAGAGGTGATCTGTGCATTATCCATAACAACGTTTTCTTTCACTATAGGACCACAGACAAATATTTATGTAAATAGGTA
TTTTTGTGTGATATTTTGTGGTACATATAACTTTTTTTAGTGTTTCACAGCATTATTATTTCATTTTATTTGTATTGAATAATGTTTTTA
GGTCCAAGTAGACTTGAATTAATGTCATAATTGTCAGTATTATTGAAAATTATGTCAACTGTACTGTTATTCATCTGTCCCATAGTTTAG
AACATGACCTGGCTATCTGGCATTGTTGCAAGTGCCTTAAATTCATGGCATCCTATTAAAAAAACAAATTTGGTGTTATGCTGCATGACA
AAGACAAACACACCTCAAAATGTTGTCCTTTCTTAGCTTGCTGCGTTTTACAGTTCTTTCTGCTAACAATTTATAAGCCTTTATTATATA
ATATTGATGAATTACAGAAATGATGAAGTTGTTCTCTTATTTCTGTTAAATGTACCAGAGCTGTGTATCTGTTAATGAGATACAGCGTCA
TTTCTGTGAAATGTATAAATGTATGTGCAGGTCAAATTAATATATGACATTCTATCAGTCTGTATACAGGTATTCCTGTTTTGCTAAGCT
GTGCAGATTCTGTAAAAATAAATTAGTGCAGTCAAGTTCTAACATATCTCATTTTATAGACTCCATTGACAATGGTCCAACCGAAAAGAA
AAATTGGAAATGACTGCTAACCAGACCTCGTTATGAAACCAATGATGAAAAAGTCACTTGGTGCACCTCTCAACAAAACAGGATGCTTTT
TCCGAGTTCTTGTATATGCAAATCATTTACGAGGCAAGTTTTCAACAGACCTAGAAAGCAAAACATTGAAAGTGTGTTGTTAGCCCTCCT
CTCTGCCCCTGAATCAACAGACAGAGCTCTGGGACCTTGGCAATGACTCAGAGGTTGGGGCTTTCTGAGTAAAGGGACATTTCTTTAAGC
ATCATCTATCAAATTTATTTCAATGTATGATGTTTTTACAACTGGTCAGTTCTTTTGTATTCTTACAGCTATGGTTATTTGATTGTCCTC
TTACAATTTGTTCTACATGAAAGAGTTCTTTGTTAGTCAGAATGCAACAAACTGTCATCAAATGGTCATTGACCACTTGCACTCTTTTGA
TGTAGATTAAAAACTTTTTCATAAATTTACCTGCTTTGATTTGCTCTGTATTTTTCCTGCAGCTGTAATTGCTGAGTGCCTGTTGTATAC

>90945_90945_8_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000374065_PRKG1_chr10_53564345_ENST00000373985_length(amino acids)=623AA_BP=134
MEGGGGSGNKTTGGLAGFFGAGGAGYSHADLAGVPLTGMNPLSPYLNVDPRYLVQDTDEFILPTGANKTRGRFELAFFTIGGCCMTGALW
ANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTALVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE
ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDR
DSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRS
EKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYA
KLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAA

--------------------------------------------------------------
>90945_90945_9_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000374065_PRKG1_chr10_53564345_ENST00000401604_length(transcript)=3591nt_BP=508nt
AGGCGCTGGCAACGCGGGGTTACCCGCTGTTATTGAGGAGTAACGGCCCAGCGGACCACCCAGGCTTGAGGCAGCGGCGGGAACCACTCG
GTTTGCTGCGATACCATGGAAGGAGGCGGGGGAAGCGGCAACAAAACCACAGGGGGATTGGCCGGCTTTTTCGGAGCCGGCGGAGCAGGT
TACTCGCACGCGGATTTGGCTGGCGTCCCGCTAACTGGTATGAACCCTCTGTCTCCTTATTTAAATGTGGATCCACGATACCTCGTGCAG
GATACAGATGAGTTTATTTTACCTACCGGAGCTAATAAAACCCGGGGCAGATTTGAGCTGGCCTTCTTTACGATTGGAGGATGTTGCATG
ACAGGGGCACTTTGGGCTAATACTCTAGGTTCTCTGGCTTTGCTCTATAGTGCATTTGGTGTCATCATTGAGAAAACACGAGGTGCAGAA
GATGACCTTAACACAGTAGCAGCTGGAACCATGACAGGCATGTTGTATAAATGTACAGCTCTTGTAAATGTAAAACTCTGGGCCATTGAT
CGACAATGTTTTCAAACAATAATGATGAGGACAGGACTCATCAAGCATACCGAGTATATGGAATTTTTAAAAAGCGTTCCAACATTCCAG
AGCCTTCCTGAAGAGATCCTCAGCAAGCTTGCTGATGTCCTTGAAGAGACCCACTATGAAAATGGAGAATATATTATCAGGCAAGGTGCA
AGAGGGGACACCTTCTTTATCATCAGCAAAGGAACGGTAAATGTCACTCGTGAAGACTCACCGAGTGAAGACCCAGTCTTTCTTAGAACT
TTAGGAAAAGGAGACTGGTTTGGAGAGAAAGCCTTGCAGGGGGAAGATGTGAGAACAGCAAACGTAATTGCTGCAGAAGCTGTAACCTGC
CTTGTGATTGACAGAGACTCTTTTAAACATTTGATTGGAGGGCTGGATGATGTTTCTAATAAAGCATATGAAGATGCAGAAGCTAAAGCA
AAATATGAAGCTGAAGCGGCTTTCTTCGCCAACCTGAAGCTGTCTGATTTCAACATCATTGATACCCTTGGAGTTGGAGGTTTCGGACGA
GTAGAACTGGTCCAGTTGAAAAGTGAAGAATCCAAAACGTTTGCAATGAAGATTCTCAAGAAACGTCACATTGTGGACACAAGACAGCAG
GAGCACATCCGCTCAGAGAAGCAGATCATGCAGGGGGCTCATTCCGATTTCATAGTGAGACTGTACAGAACATTTAAGGACAGCAAATAT
TTGTATATGTTGATGGAAGCTTGTCTAGGTGGAGAGCTCTGGACCATTCTCAGGGATAGAGGTTCGTTTGAAGATTCTACAACCAGATTT
TACACAGCATGTGTGGTAGAAGCTTTTGCCTATCTGCATTCCAAAGGAATCATTTACAGGGACCTCAAGCCAGAAAATCTCATCCTAGAT
CACCGAGGTTATGCCAAACTGGTTGATTTTGGCTTTGCAAAGAAAATAGGATTTGGAAAGAAAACATGGACTTTTTGTGGGACTCCAGAG
TATGTAGCCCCAGAGATCATCCTGAACAAAGGCCATGACATTTCAGCCGACTACTGGTCACTGGGAATCCTAATGTATGAACTCCTGACT
GGCAGCCCACCTTTCTCAGGCCCAGATCCTATGAAAACCTATAACATCATATTGAGGGGGATTGACATGATAGAATTTCCAAAGAAGATT
GCCAAAAATGCTGCTAATTTAATTAAAAAACTATGCAGGGACAATCCATCAGAAAGATTAGGGAATTTGAAAAATGGAGTAAAAGACATT
CAAAAGCACAAATGGTTTGAGGGCTTTAACTGGGAAGGCTTAAGAAAAGGTACCTTGACACCTCCTATAATACCAAGTGTTGCATCACCC
ACAGACACAAGTAATTTTGACAGTTTCCCTGAGGACAACGATGAACCACCACCTGATGACAACTCAGGATGGGATATAGACTTCTAATGT
ATTTCTCTTACCTGCTTCTGCCTTGCTGAAGACAGCTTTTTCTGAGACACAGCTGCCAGCAAACCTGAGGGAAAGAGAGAAGATTAGTGC
TCGGGGTCACCATGATGCCTTTGATCGATGCTGCTCCAGTAACTACAGTGGCATTAGGACTTACCGCTTAGATGACAATAGTGCTCTTTA
CATGTTTTCTGTTTGAACCTAAAATAGCAGTTGACATGGTGGTCCTGAAGCAAAGCCTTTCACCAGTAAAAGATGTTTTCTATTGTTGCA
ATGACCTTGCTTTGCTCTGATTATAATTTGAAAGACTGTAGGAAACACTTCAATGTAGTATAAGAGTCTGTACCTTGCTGGAATATTCAA
GAAGATGAAAGAATAATATATTGGGTACAATAGATTACTATGGTACAGAAACTGGGCTATTCCCTTTCTTCAAGTGAAGGCTGTGGGATC
TATTACTGCAGGCCGGTGTATATACCATACAAAAGAGGACCACACATCTGTTGGTCACAGAGTTCATGTCACACCAGTGCTAGAAGTTTC
ATGATTTTATTTCCCAGCAGTGCTGATGACAAGACTGAATGTTACCTTTTCTTTCTGACAGATTTTAAAAATTGATATGATAAAAGCACA
ACTGCTATAGATTCTGCTGAGACCTCTCATAGTAGGTATATATGAGTTTTCACAGAAGACTGAAAAATAATGCATGATATTTGTTTGTTT
TTTTTGATAAATTGGCATGACAGAGTGGGGAAAAAAAGCAATTCACAAAACCATTTCATATTTTTTAAAATATTGTGCTTAAAGATGGTC
CTGGAAGTAAATGACTAGCAGCCAATTGGTTTTACTTAACATACCCTCAAACTGAGGCTTAAAGTATTCCCTTTTATAAAAATAAATGCT
TGGGGTAGGGTGGAGTGGGGAGGGATTAAAACCCATCCAAAAAATAAATAAAAACTATATAGGTGCTATGTATATCTTTCATCTGTAAAT
GTCAGTGTCTGAACAGACAACACAAATTCAAATCATTATACGTGTAGCCAGAAACTCAAGCATTTTCACTAAAGTTATTAAACCAAACTC
CTGTCCAATTTCACTTATACAACATAGTCAGTCTAGAGTTGAGAGACAAAGGTAATTATAAACCTATTTGAACTAGCTTCTTGTCTTAGG
CCTGAACCAAAAAACAACAAACAAACAAAAAACAAGAATGAAAAACAGAAATAAAAGAAGTAGAAAAGACAAAGAAAGAAAGCCCAAAGT
CAAAGTTGTTAATATTTACAGGTTTACCAGATCTGGAACATTACTTATTTGAGGTCAGAGAACAAAACAAGAACCTGGCCAGGTGTTGAT
TACCTTTTAGTGAATAAGCTGAGTCCATATACTTGTCTAACTAAGAAAGCAGTACAGAGGAAAACAGGAACCTGATTTTTTTAAAATAAA
TTTTAAATAAAATAGAATTACTACAATTCTGCAATTTCATACTACCTAAAAAAGACTAGATTTGAAAATGTCAAGCTGATTTACTTTATT

>90945_90945_9_TIMM23-PRKG1_TIMM23_chr10_51606988_ENST00000374065_PRKG1_chr10_53564345_ENST00000401604_length(amino acids)=623AA_BP=134
MEGGGGSGNKTTGGLAGFFGAGGAGYSHADLAGVPLTGMNPLSPYLNVDPRYLVQDTDEFILPTGANKTRGRFELAFFTIGGCCMTGALW
ANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTALVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE
ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDR
DSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRS
EKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYA
KLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAA

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Fusion Gene PPI Analysis for TIMM23-PRKG1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TIMM23-PRKG1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TIMM23-PRKG1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource