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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:TJP2-PIP5K1B (FusionGDB2 ID:91064) |
Fusion Gene Summary for TJP2-PIP5K1B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TJP2-PIP5K1B | Fusion gene ID: 91064 | Hgene | Tgene | Gene symbol | TJP2 | PIP5K1B | Gene ID | 9414 | 8395 |
| Gene name | tight junction protein 2 | phosphatidylinositol-4-phosphate 5-kinase type 1 beta | |
| Synonyms | C9DUPq21.11|DFNA51|DUP9q21.11|PFIC4|X104|ZO2 | MSS4|STM7 | |
| Cytomap | 9q21.11 | 9q21.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | tight junction protein ZO-2Friedreich ataxia region gene X104 (tight junction protein ZO-2)zona occludens 2zonula occludens protein 2 | phosphatidylinositol 4-phosphate 5-kinase type-1 betaPIP5K1-betaPIP5KIbetaphosphatidylinositol 4-phosphate 5-kinase type I betaprotein STM-7ptdIns(4)P-5-kinase 1 betatype I phosphatidylinositol 4-phosphate 5-kinase beta | |
| Modification date | 20200320 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000265384, ENST00000348208, ENST00000377245, ENST00000453658, ENST00000535702, ENST00000539225, ENST00000377259, ENST00000498204, | ENST00000474356, ENST00000265382, ENST00000541509, | |
| Fusion gene scores | * DoF score | 13 X 14 X 8=1456 | 10 X 16 X 5=800 |
| # samples | 15 | 12 | |
| ** MAII score | log2(15/1456*10)=-3.27897594970282 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/800*10)=-2.73696559416621 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: TJP2 [Title/Abstract] AND PIP5K1B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | PIP5K1B(71357573)-TJP2(71827464), # samples:2 TJP2(71736637)-PIP5K1B(71555558), # samples:1 TJP2(71736639)-PIP5K1B(71606054), # samples:1 TJP2(71855063)-PIP5K1B(71555562), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | TJP2 | GO:0034109 | homotypic cell-cell adhesion | 21679692 |
| Fusion gene breakpoints across TJP2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across PIP5K1B (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | ESCA | TCGA-L5-A891 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| ChimerDB4 | ESCA | TCGA-L5-A891 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| ChimerDB4 | STAD | TCGA-HU-A4GH-01A | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
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Fusion Gene ORF analysis for TJP2-PIP5K1B |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000265384 | ENST00000474356 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| 5CDS-intron | ENST00000348208 | ENST00000474356 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| 5CDS-intron | ENST00000377245 | ENST00000474356 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| 5CDS-intron | ENST00000453658 | ENST00000474356 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| 5CDS-intron | ENST00000535702 | ENST00000474356 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| 5CDS-intron | ENST00000539225 | ENST00000474356 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| In-frame | ENST00000265384 | ENST00000265382 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| In-frame | ENST00000265384 | ENST00000541509 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| In-frame | ENST00000348208 | ENST00000265382 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| In-frame | ENST00000348208 | ENST00000541509 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| In-frame | ENST00000377245 | ENST00000265382 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| In-frame | ENST00000377245 | ENST00000541509 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| In-frame | ENST00000453658 | ENST00000265382 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| In-frame | ENST00000453658 | ENST00000541509 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| In-frame | ENST00000535702 | ENST00000265382 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| In-frame | ENST00000535702 | ENST00000541509 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| In-frame | ENST00000539225 | ENST00000265382 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| In-frame | ENST00000539225 | ENST00000541509 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| intron-3CDS | ENST00000265384 | ENST00000265382 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-3CDS | ENST00000265384 | ENST00000541509 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-3CDS | ENST00000348208 | ENST00000265382 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-3CDS | ENST00000348208 | ENST00000541509 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-3CDS | ENST00000377245 | ENST00000265382 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-3CDS | ENST00000377245 | ENST00000541509 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-3CDS | ENST00000377259 | ENST00000265382 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-3CDS | ENST00000377259 | ENST00000265382 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| intron-3CDS | ENST00000377259 | ENST00000541509 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-3CDS | ENST00000377259 | ENST00000541509 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| intron-3CDS | ENST00000453658 | ENST00000265382 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-3CDS | ENST00000453658 | ENST00000541509 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-3CDS | ENST00000498204 | ENST00000265382 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-3CDS | ENST00000498204 | ENST00000265382 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| intron-3CDS | ENST00000498204 | ENST00000541509 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-3CDS | ENST00000498204 | ENST00000541509 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| intron-3CDS | ENST00000535702 | ENST00000265382 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-3CDS | ENST00000535702 | ENST00000541509 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-3CDS | ENST00000539225 | ENST00000265382 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-3CDS | ENST00000539225 | ENST00000541509 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-intron | ENST00000265384 | ENST00000265382 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000265384 | ENST00000474356 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-intron | ENST00000265384 | ENST00000474356 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000265384 | ENST00000541509 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000348208 | ENST00000265382 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000348208 | ENST00000474356 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-intron | ENST00000348208 | ENST00000474356 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000348208 | ENST00000541509 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000377245 | ENST00000265382 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000377245 | ENST00000474356 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-intron | ENST00000377245 | ENST00000474356 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000377245 | ENST00000541509 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000377259 | ENST00000265382 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000377259 | ENST00000474356 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-intron | ENST00000377259 | ENST00000474356 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000377259 | ENST00000474356 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| intron-intron | ENST00000377259 | ENST00000541509 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000453658 | ENST00000265382 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000453658 | ENST00000474356 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-intron | ENST00000453658 | ENST00000474356 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000453658 | ENST00000541509 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000498204 | ENST00000265382 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000498204 | ENST00000474356 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-intron | ENST00000498204 | ENST00000474356 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000498204 | ENST00000474356 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + |
| intron-intron | ENST00000498204 | ENST00000541509 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000535702 | ENST00000265382 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000535702 | ENST00000474356 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-intron | ENST00000535702 | ENST00000474356 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000535702 | ENST00000541509 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000539225 | ENST00000265382 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000539225 | ENST00000474356 | TJP2 | chr9 | 71736637 | + | PIP5K1B | chr9 | 71555558 | + |
| intron-intron | ENST00000539225 | ENST00000474356 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| intron-intron | ENST00000539225 | ENST00000541509 | TJP2 | chr9 | 71736639 | + | PIP5K1B | chr9 | 71606054 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000453658 | TJP2 | chr9 | 71855063 | + | ENST00000541509 | PIP5K1B | chr9 | 71555562 | + | 3158 | 2685 | 2 | 2836 | 944 |
| ENST00000453658 | TJP2 | chr9 | 71855063 | + | ENST00000265382 | PIP5K1B | chr9 | 71555562 | + | 3677 | 2685 | 2 | 2950 | 982 |
| ENST00000377245 | TJP2 | chr9 | 71855063 | + | ENST00000541509 | PIP5K1B | chr9 | 71555562 | + | 3247 | 2774 | 178 | 2925 | 915 |
| ENST00000377245 | TJP2 | chr9 | 71855063 | + | ENST00000265382 | PIP5K1B | chr9 | 71555562 | + | 3766 | 2774 | 178 | 3039 | 953 |
| ENST00000348208 | TJP2 | chr9 | 71855063 | + | ENST00000541509 | PIP5K1B | chr9 | 71555562 | + | 3135 | 2662 | 66 | 2813 | 915 |
| ENST00000348208 | TJP2 | chr9 | 71855063 | + | ENST00000265382 | PIP5K1B | chr9 | 71555562 | + | 3654 | 2662 | 66 | 2927 | 953 |
| ENST00000265384 | TJP2 | chr9 | 71855063 | + | ENST00000541509 | PIP5K1B | chr9 | 71555562 | + | 3118 | 2645 | 49 | 2796 | 915 |
| ENST00000265384 | TJP2 | chr9 | 71855063 | + | ENST00000265382 | PIP5K1B | chr9 | 71555562 | + | 3637 | 2645 | 49 | 2910 | 953 |
| ENST00000535702 | TJP2 | chr9 | 71855063 | + | ENST00000541509 | PIP5K1B | chr9 | 71555562 | + | 3202 | 2729 | 127 | 2880 | 917 |
| ENST00000535702 | TJP2 | chr9 | 71855063 | + | ENST00000265382 | PIP5K1B | chr9 | 71555562 | + | 3721 | 2729 | 127 | 2994 | 955 |
| ENST00000539225 | TJP2 | chr9 | 71855063 | + | ENST00000541509 | PIP5K1B | chr9 | 71555562 | + | 3132 | 2659 | 0 | 2810 | 936 |
| ENST00000539225 | TJP2 | chr9 | 71855063 | + | ENST00000265382 | PIP5K1B | chr9 | 71555562 | + | 3651 | 2659 | 0 | 2924 | 974 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000453658 | ENST00000541509 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + | 0.002115938 | 0.9978841 |
| ENST00000453658 | ENST00000265382 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + | 0.000748074 | 0.9992519 |
| ENST00000377245 | ENST00000541509 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + | 0.00252184 | 0.9974782 |
| ENST00000377245 | ENST00000265382 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + | 0.000947247 | 0.9990527 |
| ENST00000348208 | ENST00000541509 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + | 0.002746938 | 0.9972531 |
| ENST00000348208 | ENST00000265382 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + | 0.001034679 | 0.99896526 |
| ENST00000265384 | ENST00000541509 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + | 0.00287239 | 0.9971276 |
| ENST00000265384 | ENST00000265382 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + | 0.001050903 | 0.9989491 |
| ENST00000535702 | ENST00000541509 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + | 0.001579732 | 0.99842024 |
| ENST00000535702 | ENST00000265382 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + | 0.000516009 | 0.99948394 |
| ENST00000539225 | ENST00000541509 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + | 0.002026601 | 0.9979734 |
| ENST00000539225 | ENST00000265382 | TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555562 | + | 0.000799624 | 0.9992004 |
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Fusion Genomic Features for TJP2-PIP5K1B |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555561 | + | 4.89E-05 | 0.9999511 |
| TJP2 | chr9 | 71855063 | + | PIP5K1B | chr9 | 71555561 | + | 4.89E-05 | 0.9999511 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for TJP2-PIP5K1B |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:71357573/chr9:71827464) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000265384 | + | 17 | 19 | 307_385 | 855 | 994.0 | Domain | PDZ 2 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000265384 | + | 17 | 19 | 33_120 | 855 | 994.0 | Domain | PDZ 1 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000265384 | + | 17 | 19 | 509_590 | 855 | 994.0 | Domain | PDZ 3 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000265384 | + | 17 | 19 | 604_669 | 855 | 994.0 | Domain | SH3 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000348208 | + | 17 | 21 | 307_385 | 855 | 1044.0 | Domain | PDZ 2 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000348208 | + | 17 | 21 | 33_120 | 855 | 1044.0 | Domain | PDZ 1 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000348208 | + | 17 | 21 | 509_590 | 855 | 1044.0 | Domain | PDZ 3 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000348208 | + | 17 | 21 | 604_669 | 855 | 1044.0 | Domain | SH3 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000377245 | + | 17 | 23 | 307_385 | 855 | 1191.0 | Domain | PDZ 2 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000377245 | + | 17 | 23 | 33_120 | 855 | 1191.0 | Domain | PDZ 1 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000377245 | + | 17 | 23 | 509_590 | 855 | 1191.0 | Domain | PDZ 3 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000377245 | + | 17 | 23 | 604_669 | 855 | 1191.0 | Domain | SH3 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000453658 | + | 18 | 22 | 307_385 | 832 | 1021.0 | Domain | PDZ 2 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000453658 | + | 18 | 22 | 33_120 | 832 | 1021.0 | Domain | PDZ 1 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000453658 | + | 18 | 22 | 509_590 | 832 | 1021.0 | Domain | PDZ 3 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000453658 | + | 18 | 22 | 604_669 | 832 | 1021.0 | Domain | SH3 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000535702 | + | 17 | 22 | 307_385 | 859 | 1158.0 | Domain | PDZ 2 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000535702 | + | 17 | 22 | 33_120 | 859 | 1158.0 | Domain | PDZ 1 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000535702 | + | 17 | 22 | 509_590 | 859 | 1158.0 | Domain | PDZ 3 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000535702 | + | 17 | 22 | 604_669 | 859 | 1158.0 | Domain | SH3 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000539225 | + | 17 | 23 | 307_385 | 886 | 1222.0 | Domain | PDZ 2 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000539225 | + | 17 | 23 | 33_120 | 886 | 1222.0 | Domain | PDZ 1 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000539225 | + | 17 | 23 | 509_590 | 886 | 1222.0 | Domain | PDZ 3 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000539225 | + | 17 | 23 | 604_669 | 886 | 1222.0 | Domain | SH3 |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000539225 | + | 17 | 23 | 678_876 | 886 | 1222.0 | Domain | Guanylate kinase-like |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000265384 | + | 17 | 19 | 1162_1165 | 855 | 994.0 | Compositional bias | Note=Poly-Glu |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000348208 | + | 17 | 21 | 1162_1165 | 855 | 1044.0 | Compositional bias | Note=Poly-Glu |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000377245 | + | 17 | 23 | 1162_1165 | 855 | 1191.0 | Compositional bias | Note=Poly-Glu |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000453658 | + | 18 | 22 | 1162_1165 | 832 | 1021.0 | Compositional bias | Note=Poly-Glu |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000535702 | + | 17 | 22 | 1162_1165 | 859 | 1158.0 | Compositional bias | Note=Poly-Glu |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000539225 | + | 17 | 23 | 1162_1165 | 886 | 1222.0 | Compositional bias | Note=Poly-Glu |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000265384 | + | 17 | 19 | 678_876 | 855 | 994.0 | Domain | Guanylate kinase-like |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000348208 | + | 17 | 21 | 678_876 | 855 | 1044.0 | Domain | Guanylate kinase-like |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000377245 | + | 17 | 23 | 678_876 | 855 | 1191.0 | Domain | Guanylate kinase-like |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000453658 | + | 18 | 22 | 678_876 | 832 | 1021.0 | Domain | Guanylate kinase-like |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000535702 | + | 17 | 22 | 678_876 | 859 | 1158.0 | Domain | Guanylate kinase-like |
| Tgene | PIP5K1B | chr9:71855063 | chr9:71555562 | ENST00000265382 | 12 | 16 | 25_395 | 452 | 541.0 | Domain | PIPK |
Top |
Fusion Gene Sequence for TJP2-PIP5K1B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >91064_91064_1_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000265384_PIP5K1B_chr9_71555562_ENST00000265382_length(transcript)=3637nt_BP=2645nt TGCCCAGGAGGAGTAGGAGCAGGAGCAGAAGCAGAAGCGGGGTCCGGAGCTGCGCGCCTACGCGGGACCTGTGTCCGAAATGCCGGTGCG AGGAGACCGCGGGTTTCCACCCCGGCGGGAGCTGTCAGGTTGGCTCCGCGCCCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGT GACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAAT TGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGA GGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGT GGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGG CTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGC CCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGA CCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAG CATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCG CCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGG GCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCG AACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAAC GGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTC ATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTC TGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGC GACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCC AGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAG GTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGC GGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGGTGAACACACAGGATTTCAGAGGATTAGTGCGGGAGGATGCCGTTCTCTA CCTGTTAGAAATCCCTAAAGGTGAAATGGTGACCATTTTAGCTCAGAGCCGAGCCGATGTGTATAGAGACATCCTGGCTTGTGGCAGAGG GGATTCGTTTTTTATAAGAAGCCACTTTGAATGTGAGAAGGAAACTCCACAGAGCCTGGCCTTCACCAGAGGGGAGGTCTTCCGAGTGGT AGACACACTGTATGACGGCAAGCTGGGCAACTGGCTGGCTGTGAGGATTGGGAACGAGTTGGAGAAAGGCTTAATCCCCAACAAGAGCAG AGCTGAACAAATGGCCAGTGTTCAAAATGCCCAGAGAGACAACGCTGGGGACCGGGCAGATTTCTGGAGAATGCGTGGCCAGAGGTCTGG GGTGAAGAAGAACCTGAGGAAAAGTCGGGAAGACCTCACAGCTGTTGTGTCTGTCAGCACCAAGTTCCCAGCTTATGAGAGGGTTTTGCT GCGAGAAGCTGGTTTCAAGAGACCTGTGGTCTTATTCGGCCCCATAGCTGATATAGCAATGGAAAAATTGGCTAATGAGTTACCTGACTG GTTTCAAACTGCTAAAACGGAACCAAAAGATGCAGGATCTGAGAAATCCACTGGAGTGGTCCGGTTAAATACCGTGAGGCAAATTATTGA ACAGGATAAGCATGCACTACTGGATGTGACTCCGAAAGCTGTGGACCTGTTGAATTACACCCAGTGGTTCCCAATTGTGATTTTTTTCAA CCCAGACTCCAGACAAGGTGTCAAAACCATGAGACAAAGGTTAAATCCAACGTCCAACAAAAGTTCTCGAAAGTTATTTGATCAAGCCAA CAAGCTTAAAAAAACGTGTGCACACCTTTTTACAGCCCTGGGATCCCGACACAGGCCAGACCTGGTCCCTAGCACTCCATCACTGTTTGA AGCTGCTTCCTTGGCAACCACAATTTCATCTTCTTCCTTATACGTCAATGAGCACTATCCACACGACAGGCCTACACTCTATTCAAACAG CAAAGGGTTACCTTCCAGTTCAACATTTACCTTGGAAGAGGGGACCATCTACTTGACCGCTGAGCCCAACACTCTGGAAGTGCAGGATGA CAATGCTTCTGTGCTTGACGTCTATTTATAAGTGAAAATGGTGATCACCTAAGCACATGGATGAGACGTGAGCACAGTTATGGCAGAGAA GTTTCTCCGCACCAGAATTATCCACAGCAACTTGGCTGAGCCCCACTACACACAGAGAAATCATCAACCTGACTTAAGAGTTTTCAAGAT GTCAACTTCAGGCTGATCAGCAGATGGGATGTGAAAAATACTACCCTATTCTATCATTTGCTGTTGCTTGCTGAACTGTGAAGAACTGCA TGAACTATATTTAAGCTGCTTTCTGTACCATTGCCAATCACCTTTTTGGAGTTGGAAGTGCTATTTTCCTATGGACTTTTGCATTATTTC ATTGTGCATGCATCCAGTGATTATACATAAGCAACATATGTAATCTGCTTATATATTTTTAAAAATCCATCCACACACATGGTAAATTAA GTATAAATTCTTTTGCAAAATTATAGTTCATGTCATTGAAAGTTTAAATTGGTTTCATTTAAAGATCAATATACTAGGTCTGCCTTCACT TTATAGAAAACTAGCTTCTATAAAGATTTTTTCACTGTTTACTAGTGAAATGAGAAAAGCAAAGCTATTTATAAAAGGCCTTATGTCGTG TACATACATTGTCTTTGAAATATTTGTGATCTAGTTTATTGCTTGTAAAAGAGAAATTATATAATTTATTTAGTAAATACTACTGTAAAC >91064_91064_1_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000265384_PIP5K1B_chr9_71555562_ENST00000265382_length(amino acids)=953AA_BP=863 MRAYAGPVSEMPVRGDRGFPPRRELSGWLRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGLLQ ENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRSRS WEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPD YERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGDII LKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKERPS SREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGND VGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVYRDILACGRGDSFFIRSHFECEKETP QSLAFTRGEVFRVVDTLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGDRADFWRMRGQRSGVKKNLRKSREDLTAVV SVSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTAKTEPKDAGSEKSTGVVRLNTVRQIIEQDKHALLDVTPKAVDL LNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVN -------------------------------------------------------------- >91064_91064_2_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000265384_PIP5K1B_chr9_71555562_ENST00000541509_length(transcript)=3118nt_BP=2645nt TGCCCAGGAGGAGTAGGAGCAGGAGCAGAAGCAGAAGCGGGGTCCGGAGCTGCGCGCCTACGCGGGACCTGTGTCCGAAATGCCGGTGCG AGGAGACCGCGGGTTTCCACCCCGGCGGGAGCTGTCAGGTTGGCTCCGCGCCCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGT GACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAAT TGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGA GGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGT GGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGG CTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGC CCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGA CCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAG CATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCG CCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGG GCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCG AACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAAC GGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTC ATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTC TGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGC GACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCC AGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAG GTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGC GGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGGTGAACACACAGGATTTCAGAGGATTAGTGCGGGAGGATGCCGTTCTCTA CCTGTTAGAAATCCCTAAAGGTGAAATGGTGACCATTTTAGCTCAGAGCCGAGCCGATGTGTATAGAGACATCCTGGCTTGTGGCAGAGG GGATTCGTTTTTTATAAGAAGCCACTTTGAATGTGAGAAGGAAACTCCACAGAGCCTGGCCTTCACCAGAGGGGAGGTCTTCCGAGTGGT AGACACACTGTATGACGGCAAGCTGGGCAACTGGCTGGCTGTGAGGATTGGGAACGAGTTGGAGAAAGGCTTAATCCCCAACAAGAGCAG AGCTGAACAAATGGCCAGTGTTCAAAATGCCCAGAGAGACAACGCTGGGGACCGGGCAGATTTCTGGAGAATGCGTGGCCAGAGGTCTGG GGTGAAGAAGAACCTGAGGAAAAGTCGGGAAGACCTCACAGCTGTTGTGTCTGTCAGCACCAAGTTCCCAGCTTATGAGAGGGTTTTGCT GCGAGAAGCTGGTTTCAAGAGACCTGTGGTCTTATTCGGCCCCATAGCTGATATAGCAATGGAAAAATTGGCTAATGAGTTACCTGACTG GTTTCAAACTGCTAAAACGGAACCAAAAGATGCAGGATCTGAGAAATCCACTGGAGTGGTCCGGTTAAATACCGTGAGGCAAATTATTGA ACAGGATAAGCATGCACTACTGGATGTGACTCCGAAAGCTGTGGACCTGTTGAATTACACCCAGTGGTTCCCAATTGTGATTTTTTTCAA CCCAGACTCCAGACAAGGTGTCAAAACCATGAGACAAAGGTTAAATCCAACGTCCAACAAAAGTTCTCGAAAGTTATTTGATCAAGCCAA CAAGCTTAAAAAAACGTGTGCACACCTTTTTACAGCCCTGGGATCCCGACACAGGCCAGACCTGGTCCCTAGCACTCCATCACTGTTTGA AGCTGCTTCCTTGGCAACCACAATTTCATCTTCTTCCTTATACGTCAATGAGCACTATCCACACGACAGGCCTACACTCTATTCAAACAG TAAGTGAAAATGGTGATCACCTAAGCACATGGATGAGACGTGAGCACAGTTATGGCAGAGAAGTTTCTCCGCACCAGAATTATCCACAGC AACTTGGCTGAGCCCCACTACACACAGAGAAATCATCAACCTGACTTAAGAGTTTTCAAGATGTCAACTTCAGGCTGATCAGCAGATGGG ATGTGAAAAATACTACCCTATTCTATCATTTGCTGTTGCTTGCTGAACTGTGAAGAACTGCATGAACTATATTTAAGCTGCTTTCTGTAC >91064_91064_2_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000265384_PIP5K1B_chr9_71555562_ENST00000541509_length(amino acids)=915AA_BP=863 MRAYAGPVSEMPVRGDRGFPPRRELSGWLRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGLLQ ENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRSRS WEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPD YERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGDII LKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKERPS SREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGND VGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVYRDILACGRGDSFFIRSHFECEKETP QSLAFTRGEVFRVVDTLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGDRADFWRMRGQRSGVKKNLRKSREDLTAVV SVSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTAKTEPKDAGSEKSTGVVRLNTVRQIIEQDKHALLDVTPKAVDL LNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVN -------------------------------------------------------------- >91064_91064_3_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000348208_PIP5K1B_chr9_71555562_ENST00000265382_length(transcript)=3654nt_BP=2662nt AGAGCACTGTCCGGTGGTGCCCAGGAGGAGTAGGAGCAGGAGCAGAAGCAGAAGCGGGGTCCGGAGCTGCGCGCCTACGCGGGACCTGTG TCCGAAATGCCGGTGCGAGGAGACCGCGGGTTTCCACCCCGGCGGGAGCTGTCAGGTTGGCTCCGCGCCCCAGGCATGGAAGAGCTGATA TGGGAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAA AATGGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTC AATGGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGG CCCCGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGC AGAAGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGG CGTCCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGAC CATGCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGAC CGCAGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAG TACAGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAG CCTAGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTC GTAAAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACT GAGAACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACC CTCATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAG AGACGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGA TTGTCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGA TACCAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCT AATACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATT CAAGAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGGTGAACACACAGGATTTCAGAGGATTAGTGCGG GAGGATGCCGTTCTCTACCTGTTAGAAATCCCTAAAGGTGAAATGGTGACCATTTTAGCTCAGAGCCGAGCCGATGTGTATAGAGACATC CTGGCTTGTGGCAGAGGGGATTCGTTTTTTATAAGAAGCCACTTTGAATGTGAGAAGGAAACTCCACAGAGCCTGGCCTTCACCAGAGGG GAGGTCTTCCGAGTGGTAGACACACTGTATGACGGCAAGCTGGGCAACTGGCTGGCTGTGAGGATTGGGAACGAGTTGGAGAAAGGCTTA ATCCCCAACAAGAGCAGAGCTGAACAAATGGCCAGTGTTCAAAATGCCCAGAGAGACAACGCTGGGGACCGGGCAGATTTCTGGAGAATG CGTGGCCAGAGGTCTGGGGTGAAGAAGAACCTGAGGAAAAGTCGGGAAGACCTCACAGCTGTTGTGTCTGTCAGCACCAAGTTCCCAGCT TATGAGAGGGTTTTGCTGCGAGAAGCTGGTTTCAAGAGACCTGTGGTCTTATTCGGCCCCATAGCTGATATAGCAATGGAAAAATTGGCT AATGAGTTACCTGACTGGTTTCAAACTGCTAAAACGGAACCAAAAGATGCAGGATCTGAGAAATCCACTGGAGTGGTCCGGTTAAATACC GTGAGGCAAATTATTGAACAGGATAAGCATGCACTACTGGATGTGACTCCGAAAGCTGTGGACCTGTTGAATTACACCCAGTGGTTCCCA ATTGTGATTTTTTTCAACCCAGACTCCAGACAAGGTGTCAAAACCATGAGACAAAGGTTAAATCCAACGTCCAACAAAAGTTCTCGAAAG TTATTTGATCAAGCCAACAAGCTTAAAAAAACGTGTGCACACCTTTTTACAGCCCTGGGATCCCGACACAGGCCAGACCTGGTCCCTAGC ACTCCATCACTGTTTGAAGCTGCTTCCTTGGCAACCACAATTTCATCTTCTTCCTTATACGTCAATGAGCACTATCCACACGACAGGCCT ACACTCTATTCAAACAGCAAAGGGTTACCTTCCAGTTCAACATTTACCTTGGAAGAGGGGACCATCTACTTGACCGCTGAGCCCAACACT CTGGAAGTGCAGGATGACAATGCTTCTGTGCTTGACGTCTATTTATAAGTGAAAATGGTGATCACCTAAGCACATGGATGAGACGTGAGC ACAGTTATGGCAGAGAAGTTTCTCCGCACCAGAATTATCCACAGCAACTTGGCTGAGCCCCACTACACACAGAGAAATCATCAACCTGAC TTAAGAGTTTTCAAGATGTCAACTTCAGGCTGATCAGCAGATGGGATGTGAAAAATACTACCCTATTCTATCATTTGCTGTTGCTTGCTG AACTGTGAAGAACTGCATGAACTATATTTAAGCTGCTTTCTGTACCATTGCCAATCACCTTTTTGGAGTTGGAAGTGCTATTTTCCTATG GACTTTTGCATTATTTCATTGTGCATGCATCCAGTGATTATACATAAGCAACATATGTAATCTGCTTATATATTTTTAAAAATCCATCCA CACACATGGTAAATTAAGTATAAATTCTTTTGCAAAATTATAGTTCATGTCATTGAAAGTTTAAATTGGTTTCATTTAAAGATCAATATA CTAGGTCTGCCTTCACTTTATAGAAAACTAGCTTCTATAAAGATTTTTTCACTGTTTACTAGTGAAATGAGAAAAGCAAAGCTATTTATA AAAGGCCTTATGTCGTGTACATACATTGTCTTTGAAATATTTGTGATCTAGTTTATTGCTTGTAAAAGAGAAATTATATAATTTATTTAG >91064_91064_3_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000348208_PIP5K1B_chr9_71555562_ENST00000265382_length(amino acids)=953AA_BP=863 MRAYAGPVSEMPVRGDRGFPPRRELSGWLRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGLLQ ENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRSRS WEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPD YERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGDII LKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKERPS SREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGND VGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVYRDILACGRGDSFFIRSHFECEKETP QSLAFTRGEVFRVVDTLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGDRADFWRMRGQRSGVKKNLRKSREDLTAVV SVSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTAKTEPKDAGSEKSTGVVRLNTVRQIIEQDKHALLDVTPKAVDL LNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVN -------------------------------------------------------------- >91064_91064_4_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000348208_PIP5K1B_chr9_71555562_ENST00000541509_length(transcript)=3135nt_BP=2662nt AGAGCACTGTCCGGTGGTGCCCAGGAGGAGTAGGAGCAGGAGCAGAAGCAGAAGCGGGGTCCGGAGCTGCGCGCCTACGCGGGACCTGTG TCCGAAATGCCGGTGCGAGGAGACCGCGGGTTTCCACCCCGGCGGGAGCTGTCAGGTTGGCTCCGCGCCCCAGGCATGGAAGAGCTGATA TGGGAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAA AATGGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTC AATGGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGG CCCCGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGC AGAAGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGG CGTCCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGAC CATGCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGAC CGCAGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAG TACAGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAG CCTAGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTC GTAAAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACT GAGAACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACC CTCATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAG AGACGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGA TTGTCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGA TACCAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCT AATACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATT CAAGAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGGTGAACACACAGGATTTCAGAGGATTAGTGCGG GAGGATGCCGTTCTCTACCTGTTAGAAATCCCTAAAGGTGAAATGGTGACCATTTTAGCTCAGAGCCGAGCCGATGTGTATAGAGACATC CTGGCTTGTGGCAGAGGGGATTCGTTTTTTATAAGAAGCCACTTTGAATGTGAGAAGGAAACTCCACAGAGCCTGGCCTTCACCAGAGGG GAGGTCTTCCGAGTGGTAGACACACTGTATGACGGCAAGCTGGGCAACTGGCTGGCTGTGAGGATTGGGAACGAGTTGGAGAAAGGCTTA ATCCCCAACAAGAGCAGAGCTGAACAAATGGCCAGTGTTCAAAATGCCCAGAGAGACAACGCTGGGGACCGGGCAGATTTCTGGAGAATG CGTGGCCAGAGGTCTGGGGTGAAGAAGAACCTGAGGAAAAGTCGGGAAGACCTCACAGCTGTTGTGTCTGTCAGCACCAAGTTCCCAGCT TATGAGAGGGTTTTGCTGCGAGAAGCTGGTTTCAAGAGACCTGTGGTCTTATTCGGCCCCATAGCTGATATAGCAATGGAAAAATTGGCT AATGAGTTACCTGACTGGTTTCAAACTGCTAAAACGGAACCAAAAGATGCAGGATCTGAGAAATCCACTGGAGTGGTCCGGTTAAATACC GTGAGGCAAATTATTGAACAGGATAAGCATGCACTACTGGATGTGACTCCGAAAGCTGTGGACCTGTTGAATTACACCCAGTGGTTCCCA ATTGTGATTTTTTTCAACCCAGACTCCAGACAAGGTGTCAAAACCATGAGACAAAGGTTAAATCCAACGTCCAACAAAAGTTCTCGAAAG TTATTTGATCAAGCCAACAAGCTTAAAAAAACGTGTGCACACCTTTTTACAGCCCTGGGATCCCGACACAGGCCAGACCTGGTCCCTAGC ACTCCATCACTGTTTGAAGCTGCTTCCTTGGCAACCACAATTTCATCTTCTTCCTTATACGTCAATGAGCACTATCCACACGACAGGCCT ACACTCTATTCAAACAGTAAGTGAAAATGGTGATCACCTAAGCACATGGATGAGACGTGAGCACAGTTATGGCAGAGAAGTTTCTCCGCA CCAGAATTATCCACAGCAACTTGGCTGAGCCCCACTACACACAGAGAAATCATCAACCTGACTTAAGAGTTTTCAAGATGTCAACTTCAG GCTGATCAGCAGATGGGATGTGAAAAATACTACCCTATTCTATCATTTGCTGTTGCTTGCTGAACTGTGAAGAACTGCATGAACTATATT >91064_91064_4_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000348208_PIP5K1B_chr9_71555562_ENST00000541509_length(amino acids)=915AA_BP=863 MRAYAGPVSEMPVRGDRGFPPRRELSGWLRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGLLQ ENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRSRS WEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPD YERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGDII LKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKERPS SREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGND VGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVYRDILACGRGDSFFIRSHFECEKETP QSLAFTRGEVFRVVDTLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGDRADFWRMRGQRSGVKKNLRKSREDLTAVV SVSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTAKTEPKDAGSEKSTGVVRLNTVRQIIEQDKHALLDVTPKAVDL LNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVN -------------------------------------------------------------- >91064_91064_5_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000377245_PIP5K1B_chr9_71555562_ENST00000265382_length(transcript)=3766nt_BP=2774nt GCGGAGGCGCCACGCTCGGGTCGGGGGCGGGCTGACGCCGCCGCCGCCGCGGGAGGAGGGACAAAGGGGTGGGTCCCCGCGGGTCGGCAC CCCGGCGGTTGGGCTGCGGGTCAGAGCACTGTCCGGTGGTGCCCAGGAGGAGTAGGAGCAGGAGCAGAAGCAGAAGCGGGGTCCGGAGCT GCGCGCCTACGCGGGACCTGTGTCCGAAATGCCGGTGCGAGGAGACCGCGGGTTTCCACCCCGGCGGGAGCTGTCAGGTTGGCTCCGCGC CCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGG CAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGA AAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGT CGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGA GGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTG GGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCT GGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCC ATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTA CGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCA CTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCT CCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCT CAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGT GTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAA CCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTC CAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCC AGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGA AGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGT CGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGGTGAACACACA GGATTTCAGAGGATTAGTGCGGGAGGATGCCGTTCTCTACCTGTTAGAAATCCCTAAAGGTGAAATGGTGACCATTTTAGCTCAGAGCCG AGCCGATGTGTATAGAGACATCCTGGCTTGTGGCAGAGGGGATTCGTTTTTTATAAGAAGCCACTTTGAATGTGAGAAGGAAACTCCACA GAGCCTGGCCTTCACCAGAGGGGAGGTCTTCCGAGTGGTAGACACACTGTATGACGGCAAGCTGGGCAACTGGCTGGCTGTGAGGATTGG GAACGAGTTGGAGAAAGGCTTAATCCCCAACAAGAGCAGAGCTGAACAAATGGCCAGTGTTCAAAATGCCCAGAGAGACAACGCTGGGGA CCGGGCAGATTTCTGGAGAATGCGTGGCCAGAGGTCTGGGGTGAAGAAGAACCTGAGGAAAAGTCGGGAAGACCTCACAGCTGTTGTGTC TGTCAGCACCAAGTTCCCAGCTTATGAGAGGGTTTTGCTGCGAGAAGCTGGTTTCAAGAGACCTGTGGTCTTATTCGGCCCCATAGCTGA TATAGCAATGGAAAAATTGGCTAATGAGTTACCTGACTGGTTTCAAACTGCTAAAACGGAACCAAAAGATGCAGGATCTGAGAAATCCAC TGGAGTGGTCCGGTTAAATACCGTGAGGCAAATTATTGAACAGGATAAGCATGCACTACTGGATGTGACTCCGAAAGCTGTGGACCTGTT GAATTACACCCAGTGGTTCCCAATTGTGATTTTTTTCAACCCAGACTCCAGACAAGGTGTCAAAACCATGAGACAAAGGTTAAATCCAAC GTCCAACAAAAGTTCTCGAAAGTTATTTGATCAAGCCAACAAGCTTAAAAAAACGTGTGCACACCTTTTTACAGCCCTGGGATCCCGACA CAGGCCAGACCTGGTCCCTAGCACTCCATCACTGTTTGAAGCTGCTTCCTTGGCAACCACAATTTCATCTTCTTCCTTATACGTCAATGA GCACTATCCACACGACAGGCCTACACTCTATTCAAACAGCAAAGGGTTACCTTCCAGTTCAACATTTACCTTGGAAGAGGGGACCATCTA CTTGACCGCTGAGCCCAACACTCTGGAAGTGCAGGATGACAATGCTTCTGTGCTTGACGTCTATTTATAAGTGAAAATGGTGATCACCTA AGCACATGGATGAGACGTGAGCACAGTTATGGCAGAGAAGTTTCTCCGCACCAGAATTATCCACAGCAACTTGGCTGAGCCCCACTACAC ACAGAGAAATCATCAACCTGACTTAAGAGTTTTCAAGATGTCAACTTCAGGCTGATCAGCAGATGGGATGTGAAAAATACTACCCTATTC TATCATTTGCTGTTGCTTGCTGAACTGTGAAGAACTGCATGAACTATATTTAAGCTGCTTTCTGTACCATTGCCAATCACCTTTTTGGAG TTGGAAGTGCTATTTTCCTATGGACTTTTGCATTATTTCATTGTGCATGCATCCAGTGATTATACATAAGCAACATATGTAATCTGCTTA TATATTTTTAAAAATCCATCCACACACATGGTAAATTAAGTATAAATTCTTTTGCAAAATTATAGTTCATGTCATTGAAAGTTTAAATTG GTTTCATTTAAAGATCAATATACTAGGTCTGCCTTCACTTTATAGAAAACTAGCTTCTATAAAGATTTTTTCACTGTTTACTAGTGAAAT GAGAAAAGCAAAGCTATTTATAAAAGGCCTTATGTCGTGTACATACATTGTCTTTGAAATATTTGTGATCTAGTTTATTGCTTGTAAAAG >91064_91064_5_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000377245_PIP5K1B_chr9_71555562_ENST00000265382_length(amino acids)=953AA_BP=863 MRAYAGPVSEMPVRGDRGFPPRRELSGWLRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGLLQ ENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRSRS WEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPD YERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGDII LKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKERPS SREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGND VGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVYRDILACGRGDSFFIRSHFECEKETP QSLAFTRGEVFRVVDTLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGDRADFWRMRGQRSGVKKNLRKSREDLTAVV SVSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTAKTEPKDAGSEKSTGVVRLNTVRQIIEQDKHALLDVTPKAVDL LNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVN -------------------------------------------------------------- >91064_91064_6_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000377245_PIP5K1B_chr9_71555562_ENST00000541509_length(transcript)=3247nt_BP=2774nt GCGGAGGCGCCACGCTCGGGTCGGGGGCGGGCTGACGCCGCCGCCGCCGCGGGAGGAGGGACAAAGGGGTGGGTCCCCGCGGGTCGGCAC CCCGGCGGTTGGGCTGCGGGTCAGAGCACTGTCCGGTGGTGCCCAGGAGGAGTAGGAGCAGGAGCAGAAGCAGAAGCGGGGTCCGGAGCT GCGCGCCTACGCGGGACCTGTGTCCGAAATGCCGGTGCGAGGAGACCGCGGGTTTCCACCCCGGCGGGAGCTGTCAGGTTGGCTCCGCGC CCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGG CAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGA AAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGT CGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGA GGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTG GGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCT GGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCC ATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTA CGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCA CTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCT CCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCT CAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGT GTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAA CCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTC CAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCC AGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGA AGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGT CGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGGTGAACACACA GGATTTCAGAGGATTAGTGCGGGAGGATGCCGTTCTCTACCTGTTAGAAATCCCTAAAGGTGAAATGGTGACCATTTTAGCTCAGAGCCG AGCCGATGTGTATAGAGACATCCTGGCTTGTGGCAGAGGGGATTCGTTTTTTATAAGAAGCCACTTTGAATGTGAGAAGGAAACTCCACA GAGCCTGGCCTTCACCAGAGGGGAGGTCTTCCGAGTGGTAGACACACTGTATGACGGCAAGCTGGGCAACTGGCTGGCTGTGAGGATTGG GAACGAGTTGGAGAAAGGCTTAATCCCCAACAAGAGCAGAGCTGAACAAATGGCCAGTGTTCAAAATGCCCAGAGAGACAACGCTGGGGA CCGGGCAGATTTCTGGAGAATGCGTGGCCAGAGGTCTGGGGTGAAGAAGAACCTGAGGAAAAGTCGGGAAGACCTCACAGCTGTTGTGTC TGTCAGCACCAAGTTCCCAGCTTATGAGAGGGTTTTGCTGCGAGAAGCTGGTTTCAAGAGACCTGTGGTCTTATTCGGCCCCATAGCTGA TATAGCAATGGAAAAATTGGCTAATGAGTTACCTGACTGGTTTCAAACTGCTAAAACGGAACCAAAAGATGCAGGATCTGAGAAATCCAC TGGAGTGGTCCGGTTAAATACCGTGAGGCAAATTATTGAACAGGATAAGCATGCACTACTGGATGTGACTCCGAAAGCTGTGGACCTGTT GAATTACACCCAGTGGTTCCCAATTGTGATTTTTTTCAACCCAGACTCCAGACAAGGTGTCAAAACCATGAGACAAAGGTTAAATCCAAC GTCCAACAAAAGTTCTCGAAAGTTATTTGATCAAGCCAACAAGCTTAAAAAAACGTGTGCACACCTTTTTACAGCCCTGGGATCCCGACA CAGGCCAGACCTGGTCCCTAGCACTCCATCACTGTTTGAAGCTGCTTCCTTGGCAACCACAATTTCATCTTCTTCCTTATACGTCAATGA GCACTATCCACACGACAGGCCTACACTCTATTCAAACAGTAAGTGAAAATGGTGATCACCTAAGCACATGGATGAGACGTGAGCACAGTT ATGGCAGAGAAGTTTCTCCGCACCAGAATTATCCACAGCAACTTGGCTGAGCCCCACTACACACAGAGAAATCATCAACCTGACTTAAGA GTTTTCAAGATGTCAACTTCAGGCTGATCAGCAGATGGGATGTGAAAAATACTACCCTATTCTATCATTTGCTGTTGCTTGCTGAACTGT GAAGAACTGCATGAACTATATTTAAGCTGCTTTCTGTACCATTGCCAATCACCTTTTTGGAGTTGGAAGTGCTATTTTCCTATGGACTTT >91064_91064_6_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000377245_PIP5K1B_chr9_71555562_ENST00000541509_length(amino acids)=915AA_BP=863 MRAYAGPVSEMPVRGDRGFPPRRELSGWLRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGLLQ ENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRSRS WEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPD YERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGDII LKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKERPS SREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGND VGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVYRDILACGRGDSFFIRSHFECEKETP QSLAFTRGEVFRVVDTLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGDRADFWRMRGQRSGVKKNLRKSREDLTAVV SVSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTAKTEPKDAGSEKSTGVVRLNTVRQIIEQDKHALLDVTPKAVDL LNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVN -------------------------------------------------------------- >91064_91064_7_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000453658_PIP5K1B_chr9_71555562_ENST00000265382_length(transcript)=3677nt_BP=2685nt AGCTGCGTCTCCCTCCCGGGGCTCGCGCGCCCAGAACCCTCCGGTCTCAAGGAAGCAGGGTGCGAAGTACCACATTACTGTCATCTCCCT GTGAGTGGGATTGGCACCCCGGCTGCAGCTCCAGGAGCAAGTACTCCAGGAAGCACAGAGCTGTACCAGTACACGGCCCACGTTGCCAGG CCCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAG GCAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAG AAAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGG TCGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTG AGGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCT GGGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCC TGGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGC CATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACT ACGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGC ACTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTC TCCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTC TCAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGG TGTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAA ACCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTT CCAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCC CAGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTG AAGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATG TCGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGGTGAACACAC AGGATTTCAGAGGATTAGTGCGGGAGGATGCCGTTCTCTACCTGTTAGAAATCCCTAAAGGTGAAATGGTGACCATTTTAGCTCAGAGCC GAGCCGATGTGTATAGAGACATCCTGGCTTGTGGCAGAGGGGATTCGTTTTTTATAAGAAGCCACTTTGAATGTGAGAAGGAAACTCCAC AGAGCCTGGCCTTCACCAGAGGGGAGGTCTTCCGAGTGGTAGACACACTGTATGACGGCAAGCTGGGCAACTGGCTGGCTGTGAGGATTG GGAACGAGTTGGAGAAAGGCTTAATCCCCAACAAGAGCAGAGCTGAACAAATGGCCAGTGTTCAAAATGCCCAGAGAGACAACGCTGGGG ACCGGGCAGATTTCTGGAGAATGCGTGGCCAGAGGTCTGGGGTGAAGAAGAACCTGAGGAAAAGTCGGGAAGACCTCACAGCTGTTGTGT CTGTCAGCACCAAGTTCCCAGCTTATGAGAGGGTTTTGCTGCGAGAAGCTGGTTTCAAGAGACCTGTGGTCTTATTCGGCCCCATAGCTG ATATAGCAATGGAAAAATTGGCTAATGAGTTACCTGACTGGTTTCAAACTGCTAAAACGGAACCAAAAGATGCAGGATCTGAGAAATCCA CTGGAGTGGTCCGGTTAAATACCGTGAGGCAAATTATTGAACAGGATAAGCATGCACTACTGGATGTGACTCCGAAAGCTGTGGACCTGT TGAATTACACCCAGTGGTTCCCAATTGTGATTTTTTTCAACCCAGACTCCAGACAAGGTGTCAAAACCATGAGACAAAGGTTAAATCCAA CGTCCAACAAAAGTTCTCGAAAGTTATTTGATCAAGCCAACAAGCTTAAAAAAACGTGTGCACACCTTTTTACAGCCCTGGGATCCCGAC ACAGGCCAGACCTGGTCCCTAGCACTCCATCACTGTTTGAAGCTGCTTCCTTGGCAACCACAATTTCATCTTCTTCCTTATACGTCAATG AGCACTATCCACACGACAGGCCTACACTCTATTCAAACAGCAAAGGGTTACCTTCCAGTTCAACATTTACCTTGGAAGAGGGGACCATCT ACTTGACCGCTGAGCCCAACACTCTGGAAGTGCAGGATGACAATGCTTCTGTGCTTGACGTCTATTTATAAGTGAAAATGGTGATCACCT AAGCACATGGATGAGACGTGAGCACAGTTATGGCAGAGAAGTTTCTCCGCACCAGAATTATCCACAGCAACTTGGCTGAGCCCCACTACA CACAGAGAAATCATCAACCTGACTTAAGAGTTTTCAAGATGTCAACTTCAGGCTGATCAGCAGATGGGATGTGAAAAATACTACCCTATT CTATCATTTGCTGTTGCTTGCTGAACTGTGAAGAACTGCATGAACTATATTTAAGCTGCTTTCTGTACCATTGCCAATCACCTTTTTGGA GTTGGAAGTGCTATTTTCCTATGGACTTTTGCATTATTTCATTGTGCATGCATCCAGTGATTATACATAAGCAACATATGTAATCTGCTT ATATATTTTTAAAAATCCATCCACACACATGGTAAATTAAGTATAAATTCTTTTGCAAAATTATAGTTCATGTCATTGAAAGTTTAAATT GGTTTCATTTAAAGATCAATATACTAGGTCTGCCTTCACTTTATAGAAAACTAGCTTCTATAAAGATTTTTTCACTGTTTACTAGTGAAA TGAGAAAAGCAAAGCTATTTATAAAAGGCCTTATGTCGTGTACATACATTGTCTTTGAAATATTTGTGATCTAGTTTATTGCTTGTAAAA >91064_91064_7_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000453658_PIP5K1B_chr9_71555562_ENST00000265382_length(amino acids)=982AA_BP=892 LRLPPGARAPRTLRSQGSRVRSTTLLSSPCEWDWHPGCSSRSKYSRKHRAVPVHGPRCQAPGMEELIWEQYTVTLQKDSKRGFGIAVSGG RDNPHFENGETSIVISDVLPGGPADGLLQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFE VMDEFDGRSFRSGYSERSRLNSHGGRSRSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGP SRDRDRDRSRGRSIDQDYERAYHRAYDPDYERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGL RLGSQIFVKEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESN RSFSPEERRHQYSDYDYHSSSEKLKERPSSREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPE DEAIYGPNTKMVRFKKGDSVGLRLAGGNDVGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSR ADVYRDILACGRGDSFFIRSHFECEKETPQSLAFTRGEVFRVVDTLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGD RADFWRMRGQRSGVKKNLRKSREDLTAVVSVSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTAKTEPKDAGSEKST GVVRLNTVRQIIEQDKHALLDVTPKAVDLLNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTALGSRH -------------------------------------------------------------- >91064_91064_8_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000453658_PIP5K1B_chr9_71555562_ENST00000541509_length(transcript)=3158nt_BP=2685nt AGCTGCGTCTCCCTCCCGGGGCTCGCGCGCCCAGAACCCTCCGGTCTCAAGGAAGCAGGGTGCGAAGTACCACATTACTGTCATCTCCCT GTGAGTGGGATTGGCACCCCGGCTGCAGCTCCAGGAGCAAGTACTCCAGGAAGCACAGAGCTGTACCAGTACACGGCCCACGTTGCCAGG CCCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAG GCAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAG AAAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGG TCGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTG AGGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCT GGGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCC TGGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGC CATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACT ACGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGC ACTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTC TCCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTC TCAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGG TGTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAA ACCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTT CCAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCC CAGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTG AAGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATG TCGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGGTGAACACAC AGGATTTCAGAGGATTAGTGCGGGAGGATGCCGTTCTCTACCTGTTAGAAATCCCTAAAGGTGAAATGGTGACCATTTTAGCTCAGAGCC GAGCCGATGTGTATAGAGACATCCTGGCTTGTGGCAGAGGGGATTCGTTTTTTATAAGAAGCCACTTTGAATGTGAGAAGGAAACTCCAC AGAGCCTGGCCTTCACCAGAGGGGAGGTCTTCCGAGTGGTAGACACACTGTATGACGGCAAGCTGGGCAACTGGCTGGCTGTGAGGATTG GGAACGAGTTGGAGAAAGGCTTAATCCCCAACAAGAGCAGAGCTGAACAAATGGCCAGTGTTCAAAATGCCCAGAGAGACAACGCTGGGG ACCGGGCAGATTTCTGGAGAATGCGTGGCCAGAGGTCTGGGGTGAAGAAGAACCTGAGGAAAAGTCGGGAAGACCTCACAGCTGTTGTGT CTGTCAGCACCAAGTTCCCAGCTTATGAGAGGGTTTTGCTGCGAGAAGCTGGTTTCAAGAGACCTGTGGTCTTATTCGGCCCCATAGCTG ATATAGCAATGGAAAAATTGGCTAATGAGTTACCTGACTGGTTTCAAACTGCTAAAACGGAACCAAAAGATGCAGGATCTGAGAAATCCA CTGGAGTGGTCCGGTTAAATACCGTGAGGCAAATTATTGAACAGGATAAGCATGCACTACTGGATGTGACTCCGAAAGCTGTGGACCTGT TGAATTACACCCAGTGGTTCCCAATTGTGATTTTTTTCAACCCAGACTCCAGACAAGGTGTCAAAACCATGAGACAAAGGTTAAATCCAA CGTCCAACAAAAGTTCTCGAAAGTTATTTGATCAAGCCAACAAGCTTAAAAAAACGTGTGCACACCTTTTTACAGCCCTGGGATCCCGAC ACAGGCCAGACCTGGTCCCTAGCACTCCATCACTGTTTGAAGCTGCTTCCTTGGCAACCACAATTTCATCTTCTTCCTTATACGTCAATG AGCACTATCCACACGACAGGCCTACACTCTATTCAAACAGTAAGTGAAAATGGTGATCACCTAAGCACATGGATGAGACGTGAGCACAGT TATGGCAGAGAAGTTTCTCCGCACCAGAATTATCCACAGCAACTTGGCTGAGCCCCACTACACACAGAGAAATCATCAACCTGACTTAAG AGTTTTCAAGATGTCAACTTCAGGCTGATCAGCAGATGGGATGTGAAAAATACTACCCTATTCTATCATTTGCTGTTGCTTGCTGAACTG TGAAGAACTGCATGAACTATATTTAAGCTGCTTTCTGTACCATTGCCAATCACCTTTTTGGAGTTGGAAGTGCTATTTTCCTATGGACTT >91064_91064_8_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000453658_PIP5K1B_chr9_71555562_ENST00000541509_length(amino acids)=944AA_BP=892 LRLPPGARAPRTLRSQGSRVRSTTLLSSPCEWDWHPGCSSRSKYSRKHRAVPVHGPRCQAPGMEELIWEQYTVTLQKDSKRGFGIAVSGG RDNPHFENGETSIVISDVLPGGPADGLLQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFE VMDEFDGRSFRSGYSERSRLNSHGGRSRSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGP SRDRDRDRSRGRSIDQDYERAYHRAYDPDYERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGL RLGSQIFVKEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESN RSFSPEERRHQYSDYDYHSSSEKLKERPSSREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPE DEAIYGPNTKMVRFKKGDSVGLRLAGGNDVGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSR ADVYRDILACGRGDSFFIRSHFECEKETPQSLAFTRGEVFRVVDTLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGD RADFWRMRGQRSGVKKNLRKSREDLTAVVSVSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTAKTEPKDAGSEKST GVVRLNTVRQIIEQDKHALLDVTPKAVDLLNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTALGSRH -------------------------------------------------------------- >91064_91064_9_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000535702_PIP5K1B_chr9_71555562_ENST00000265382_length(transcript)=3721nt_BP=2729nt ATATGGATGTGTCACTGTGTGAGATGACAACAGGATTTGCTGGAAATGTGGGCCACTATTGTATCCGCCTTACGTAACCACATGGAGTGA TGGAAATGGGTGAGCAGCCCGGAATGTAGGCGGTGGCCTGGCCCATGCATCTCCAGAGACCATGAAGACTGCTCAAGCCCTACATAGGAT GTGGATCCAGGCTGTTAAAAAGTTGAGGAGATGGAAAGGCCGTGCCCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGTGACCCT ACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAATTGTCAT TTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGAGGATGT GCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGTGGCCGC ACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGGCTACAG CGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGCCCGGAG CCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGACCGCAG CCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAGCATTGA CCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCGCCACGA TGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGGGCCCAT CGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCGAACGGG TCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAACGGATGC TCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTCATTAAA TGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTCTGATTA TGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGCGACACC CACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCCAGCTCC TCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAGGTTCAA GAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGCGGAGCA GGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGGTGAACACACAGGATTTCAGAGGATTAGTGCGGGAGGATGCCGTTCTCTACCTGTT AGAAATCCCTAAAGGTGAAATGGTGACCATTTTAGCTCAGAGCCGAGCCGATGTGTATAGAGACATCCTGGCTTGTGGCAGAGGGGATTC GTTTTTTATAAGAAGCCACTTTGAATGTGAGAAGGAAACTCCACAGAGCCTGGCCTTCACCAGAGGGGAGGTCTTCCGAGTGGTAGACAC ACTGTATGACGGCAAGCTGGGCAACTGGCTGGCTGTGAGGATTGGGAACGAGTTGGAGAAAGGCTTAATCCCCAACAAGAGCAGAGCTGA ACAAATGGCCAGTGTTCAAAATGCCCAGAGAGACAACGCTGGGGACCGGGCAGATTTCTGGAGAATGCGTGGCCAGAGGTCTGGGGTGAA GAAGAACCTGAGGAAAAGTCGGGAAGACCTCACAGCTGTTGTGTCTGTCAGCACCAAGTTCCCAGCTTATGAGAGGGTTTTGCTGCGAGA AGCTGGTTTCAAGAGACCTGTGGTCTTATTCGGCCCCATAGCTGATATAGCAATGGAAAAATTGGCTAATGAGTTACCTGACTGGTTTCA AACTGCTAAAACGGAACCAAAAGATGCAGGATCTGAGAAATCCACTGGAGTGGTCCGGTTAAATACCGTGAGGCAAATTATTGAACAGGA TAAGCATGCACTACTGGATGTGACTCCGAAAGCTGTGGACCTGTTGAATTACACCCAGTGGTTCCCAATTGTGATTTTTTTCAACCCAGA CTCCAGACAAGGTGTCAAAACCATGAGACAAAGGTTAAATCCAACGTCCAACAAAAGTTCTCGAAAGTTATTTGATCAAGCCAACAAGCT TAAAAAAACGTGTGCACACCTTTTTACAGCCCTGGGATCCCGACACAGGCCAGACCTGGTCCCTAGCACTCCATCACTGTTTGAAGCTGC TTCCTTGGCAACCACAATTTCATCTTCTTCCTTATACGTCAATGAGCACTATCCACACGACAGGCCTACACTCTATTCAAACAGCAAAGG GTTACCTTCCAGTTCAACATTTACCTTGGAAGAGGGGACCATCTACTTGACCGCTGAGCCCAACACTCTGGAAGTGCAGGATGACAATGC TTCTGTGCTTGACGTCTATTTATAAGTGAAAATGGTGATCACCTAAGCACATGGATGAGACGTGAGCACAGTTATGGCAGAGAAGTTTCT CCGCACCAGAATTATCCACAGCAACTTGGCTGAGCCCCACTACACACAGAGAAATCATCAACCTGACTTAAGAGTTTTCAAGATGTCAAC TTCAGGCTGATCAGCAGATGGGATGTGAAAAATACTACCCTATTCTATCATTTGCTGTTGCTTGCTGAACTGTGAAGAACTGCATGAACT ATATTTAAGCTGCTTTCTGTACCATTGCCAATCACCTTTTTGGAGTTGGAAGTGCTATTTTCCTATGGACTTTTGCATTATTTCATTGTG CATGCATCCAGTGATTATACATAAGCAACATATGTAATCTGCTTATATATTTTTAAAAATCCATCCACACACATGGTAAATTAAGTATAA ATTCTTTTGCAAAATTATAGTTCATGTCATTGAAAGTTTAAATTGGTTTCATTTAAAGATCAATATACTAGGTCTGCCTTCACTTTATAG AAAACTAGCTTCTATAAAGATTTTTTCACTGTTTACTAGTGAAATGAGAAAAGCAAAGCTATTTATAAAAGGCCTTATGTCGTGTACATA CATTGTCTTTGAAATATTTGTGATCTAGTTTATTGCTTGTAAAAGAGAAATTATATAATTTATTTAGTAAATACTACTGTAAACTATAGT >91064_91064_9_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000535702_PIP5K1B_chr9_71555562_ENST00000265382_length(amino acids)=955AA_BP=865 MAHASPETMKTAQALHRMWIQAVKKLRRWKGRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGL LQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRS RSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYD PDYERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGD IILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKER PSSREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGG NDVGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVYRDILACGRGDSFFIRSHFECEKE TPQSLAFTRGEVFRVVDTLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGDRADFWRMRGQRSGVKKNLRKSREDLTA VVSVSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTAKTEPKDAGSEKSTGVVRLNTVRQIIEQDKHALLDVTPKAV DLLNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTALGSRHRPDLVPSTPSLFEAASLATTISSSSLY -------------------------------------------------------------- >91064_91064_10_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000535702_PIP5K1B_chr9_71555562_ENST00000541509_length(transcript)=3202nt_BP=2729nt ATATGGATGTGTCACTGTGTGAGATGACAACAGGATTTGCTGGAAATGTGGGCCACTATTGTATCCGCCTTACGTAACCACATGGAGTGA TGGAAATGGGTGAGCAGCCCGGAATGTAGGCGGTGGCCTGGCCCATGCATCTCCAGAGACCATGAAGACTGCTCAAGCCCTACATAGGAT GTGGATCCAGGCTGTTAAAAAGTTGAGGAGATGGAAAGGCCGTGCCCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGTGACCCT ACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAATTGTCAT TTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGAGGATGT GCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGTGGCCGC ACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGGCTACAG CGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGCCCGGAG CCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGACCGCAG CCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAGCATTGA CCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCGCCACGA TGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGGGCCCAT CGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCGAACGGG TCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAACGGATGC TCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTCATTAAA TGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTCTGATTA TGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGCGACACC CACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCCAGCTCC TCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAGGTTCAA GAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGCGGAGCA GGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGGTGAACACACAGGATTTCAGAGGATTAGTGCGGGAGGATGCCGTTCTCTACCTGTT AGAAATCCCTAAAGGTGAAATGGTGACCATTTTAGCTCAGAGCCGAGCCGATGTGTATAGAGACATCCTGGCTTGTGGCAGAGGGGATTC GTTTTTTATAAGAAGCCACTTTGAATGTGAGAAGGAAACTCCACAGAGCCTGGCCTTCACCAGAGGGGAGGTCTTCCGAGTGGTAGACAC ACTGTATGACGGCAAGCTGGGCAACTGGCTGGCTGTGAGGATTGGGAACGAGTTGGAGAAAGGCTTAATCCCCAACAAGAGCAGAGCTGA ACAAATGGCCAGTGTTCAAAATGCCCAGAGAGACAACGCTGGGGACCGGGCAGATTTCTGGAGAATGCGTGGCCAGAGGTCTGGGGTGAA GAAGAACCTGAGGAAAAGTCGGGAAGACCTCACAGCTGTTGTGTCTGTCAGCACCAAGTTCCCAGCTTATGAGAGGGTTTTGCTGCGAGA AGCTGGTTTCAAGAGACCTGTGGTCTTATTCGGCCCCATAGCTGATATAGCAATGGAAAAATTGGCTAATGAGTTACCTGACTGGTTTCA AACTGCTAAAACGGAACCAAAAGATGCAGGATCTGAGAAATCCACTGGAGTGGTCCGGTTAAATACCGTGAGGCAAATTATTGAACAGGA TAAGCATGCACTACTGGATGTGACTCCGAAAGCTGTGGACCTGTTGAATTACACCCAGTGGTTCCCAATTGTGATTTTTTTCAACCCAGA CTCCAGACAAGGTGTCAAAACCATGAGACAAAGGTTAAATCCAACGTCCAACAAAAGTTCTCGAAAGTTATTTGATCAAGCCAACAAGCT TAAAAAAACGTGTGCACACCTTTTTACAGCCCTGGGATCCCGACACAGGCCAGACCTGGTCCCTAGCACTCCATCACTGTTTGAAGCTGC TTCCTTGGCAACCACAATTTCATCTTCTTCCTTATACGTCAATGAGCACTATCCACACGACAGGCCTACACTCTATTCAAACAGTAAGTG AAAATGGTGATCACCTAAGCACATGGATGAGACGTGAGCACAGTTATGGCAGAGAAGTTTCTCCGCACCAGAATTATCCACAGCAACTTG GCTGAGCCCCACTACACACAGAGAAATCATCAACCTGACTTAAGAGTTTTCAAGATGTCAACTTCAGGCTGATCAGCAGATGGGATGTGA AAAATACTACCCTATTCTATCATTTGCTGTTGCTTGCTGAACTGTGAAGAACTGCATGAACTATATTTAAGCTGCTTTCTGTACCATTGC >91064_91064_10_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000535702_PIP5K1B_chr9_71555562_ENST00000541509_length(amino acids)=917AA_BP=865 MAHASPETMKTAQALHRMWIQAVKKLRRWKGRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGL LQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRS RSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYD PDYERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGD IILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKER PSSREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGG NDVGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVYRDILACGRGDSFFIRSHFECEKE TPQSLAFTRGEVFRVVDTLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGDRADFWRMRGQRSGVKKNLRKSREDLTA VVSVSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTAKTEPKDAGSEKSTGVVRLNTVRQIIEQDKHALLDVTPKAV DLLNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTALGSRHRPDLVPSTPSLFEAASLATTISSSSLY -------------------------------------------------------------- >91064_91064_11_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000539225_PIP5K1B_chr9_71555562_ENST00000265382_length(transcript)=3651nt_BP=2659nt ATGAAGACTGCTCAAGCCCTACATAGGATGTGGATCCAGGCTGTTAAAAAGTTGAGGAGATGGAAAGGCCGTGTGAGTCCCTCTGCAAGC TCTCCCCTTGTTTTCCCCAACCTTTCTTCATGGGAAGGGGAGGGAAGCAAAACCATTCTCACAGCCCCAGGCATGGAAGAGCTGATATGG GAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAAAAT GGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTCAAT GGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGGCCC CGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGCAGA AGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGGCGT CCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGACCAT GCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGACCGC AGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAGTAC AGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAGCCT AGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTCGTA AAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACTGAG AACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACCCTC ATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAGAGA CGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGATTG TCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGATAC CAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCTAAT ACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATTCAA GAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGGTGAACACACAGGATTTCAGAGGATTAGTGCGGGAG GATGCCGTTCTCTACCTGTTAGAAATCCCTAAAGGTGAAATGGTGACCATTTTAGCTCAGAGCCGAGCCGATGTGTATAGAGACATCCTG GCTTGTGGCAGAGGGGATTCGTTTTTTATAAGAAGCCACTTTGAATGTGAGAAGGAAACTCCACAGAGCCTGGCCTTCACCAGAGGGGAG GTCTTCCGAGTGGTAGACACACTGTATGACGGCAAGCTGGGCAACTGGCTGGCTGTGAGGATTGGGAACGAGTTGGAGAAAGGCTTAATC CCCAACAAGAGCAGAGCTGAACAAATGGCCAGTGTTCAAAATGCCCAGAGAGACAACGCTGGGGACCGGGCAGATTTCTGGAGAATGCGT GGCCAGAGGTCTGGGGTGAAGAAGAACCTGAGGAAAAGTCGGGAAGACCTCACAGCTGTTGTGTCTGTCAGCACCAAGTTCCCAGCTTAT GAGAGGGTTTTGCTGCGAGAAGCTGGTTTCAAGAGACCTGTGGTCTTATTCGGCCCCATAGCTGATATAGCAATGGAAAAATTGGCTAAT GAGTTACCTGACTGGTTTCAAACTGCTAAAACGGAACCAAAAGATGCAGGATCTGAGAAATCCACTGGAGTGGTCCGGTTAAATACCGTG AGGCAAATTATTGAACAGGATAAGCATGCACTACTGGATGTGACTCCGAAAGCTGTGGACCTGTTGAATTACACCCAGTGGTTCCCAATT GTGATTTTTTTCAACCCAGACTCCAGACAAGGTGTCAAAACCATGAGACAAAGGTTAAATCCAACGTCCAACAAAAGTTCTCGAAAGTTA TTTGATCAAGCCAACAAGCTTAAAAAAACGTGTGCACACCTTTTTACAGCCCTGGGATCCCGACACAGGCCAGACCTGGTCCCTAGCACT CCATCACTGTTTGAAGCTGCTTCCTTGGCAACCACAATTTCATCTTCTTCCTTATACGTCAATGAGCACTATCCACACGACAGGCCTACA CTCTATTCAAACAGCAAAGGGTTACCTTCCAGTTCAACATTTACCTTGGAAGAGGGGACCATCTACTTGACCGCTGAGCCCAACACTCTG GAAGTGCAGGATGACAATGCTTCTGTGCTTGACGTCTATTTATAAGTGAAAATGGTGATCACCTAAGCACATGGATGAGACGTGAGCACA GTTATGGCAGAGAAGTTTCTCCGCACCAGAATTATCCACAGCAACTTGGCTGAGCCCCACTACACACAGAGAAATCATCAACCTGACTTA AGAGTTTTCAAGATGTCAACTTCAGGCTGATCAGCAGATGGGATGTGAAAAATACTACCCTATTCTATCATTTGCTGTTGCTTGCTGAAC TGTGAAGAACTGCATGAACTATATTTAAGCTGCTTTCTGTACCATTGCCAATCACCTTTTTGGAGTTGGAAGTGCTATTTTCCTATGGAC TTTTGCATTATTTCATTGTGCATGCATCCAGTGATTATACATAAGCAACATATGTAATCTGCTTATATATTTTTAAAAATCCATCCACAC ACATGGTAAATTAAGTATAAATTCTTTTGCAAAATTATAGTTCATGTCATTGAAAGTTTAAATTGGTTTCATTTAAAGATCAATATACTA GGTCTGCCTTCACTTTATAGAAAACTAGCTTCTATAAAGATTTTTTCACTGTTTACTAGTGAAATGAGAAAAGCAAAGCTATTTATAAAA GGCCTTATGTCGTGTACATACATTGTCTTTGAAATATTTGTGATCTAGTTTATTGCTTGTAAAAGAGAAATTATATAATTTATTTAGTAA >91064_91064_11_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000539225_PIP5K1B_chr9_71555562_ENST00000265382_length(amino acids)=974AA_BP=884 MKTAQALHRMWIQAVKKLRRWKGRVSPSASSPLVFPNLSSWEGEGSKTILTAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFEN GETSIVISDVLPGGPADGLLQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGR SFRSGYSERSRLNSHGGRSRSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDR SRGRSIDQDYERAYHRAYDPDYERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFV KEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEER RHQYSDYDYHSSSEKLKERPSSREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPN TKMVRFKKGDSVGLRLAGGNDVGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVYRDIL ACGRGDSFFIRSHFECEKETPQSLAFTRGEVFRVVDTLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGDRADFWRMR GQRSGVKKNLRKSREDLTAVVSVSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTAKTEPKDAGSEKSTGVVRLNTV RQIIEQDKHALLDVTPKAVDLLNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTALGSRHRPDLVPST -------------------------------------------------------------- >91064_91064_12_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000539225_PIP5K1B_chr9_71555562_ENST00000541509_length(transcript)=3132nt_BP=2659nt ATGAAGACTGCTCAAGCCCTACATAGGATGTGGATCCAGGCTGTTAAAAAGTTGAGGAGATGGAAAGGCCGTGTGAGTCCCTCTGCAAGC TCTCCCCTTGTTTTCCCCAACCTTTCTTCATGGGAAGGGGAGGGAAGCAAAACCATTCTCACAGCCCCAGGCATGGAAGAGCTGATATGG GAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAAAAT GGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTCAAT GGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGGCCC CGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGCAGA AGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGGCGT CCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGACCAT GCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGACCGC AGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAGTAC AGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAGCCT AGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTCGTA AAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACTGAG AACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACCCTC ATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAGAGA CGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGATTG TCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGATAC CAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCTAAT ACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATTCAA GAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGGTGAACACACAGGATTTCAGAGGATTAGTGCGGGAG GATGCCGTTCTCTACCTGTTAGAAATCCCTAAAGGTGAAATGGTGACCATTTTAGCTCAGAGCCGAGCCGATGTGTATAGAGACATCCTG GCTTGTGGCAGAGGGGATTCGTTTTTTATAAGAAGCCACTTTGAATGTGAGAAGGAAACTCCACAGAGCCTGGCCTTCACCAGAGGGGAG GTCTTCCGAGTGGTAGACACACTGTATGACGGCAAGCTGGGCAACTGGCTGGCTGTGAGGATTGGGAACGAGTTGGAGAAAGGCTTAATC CCCAACAAGAGCAGAGCTGAACAAATGGCCAGTGTTCAAAATGCCCAGAGAGACAACGCTGGGGACCGGGCAGATTTCTGGAGAATGCGT GGCCAGAGGTCTGGGGTGAAGAAGAACCTGAGGAAAAGTCGGGAAGACCTCACAGCTGTTGTGTCTGTCAGCACCAAGTTCCCAGCTTAT GAGAGGGTTTTGCTGCGAGAAGCTGGTTTCAAGAGACCTGTGGTCTTATTCGGCCCCATAGCTGATATAGCAATGGAAAAATTGGCTAAT GAGTTACCTGACTGGTTTCAAACTGCTAAAACGGAACCAAAAGATGCAGGATCTGAGAAATCCACTGGAGTGGTCCGGTTAAATACCGTG AGGCAAATTATTGAACAGGATAAGCATGCACTACTGGATGTGACTCCGAAAGCTGTGGACCTGTTGAATTACACCCAGTGGTTCCCAATT GTGATTTTTTTCAACCCAGACTCCAGACAAGGTGTCAAAACCATGAGACAAAGGTTAAATCCAACGTCCAACAAAAGTTCTCGAAAGTTA TTTGATCAAGCCAACAAGCTTAAAAAAACGTGTGCACACCTTTTTACAGCCCTGGGATCCCGACACAGGCCAGACCTGGTCCCTAGCACT CCATCACTGTTTGAAGCTGCTTCCTTGGCAACCACAATTTCATCTTCTTCCTTATACGTCAATGAGCACTATCCACACGACAGGCCTACA CTCTATTCAAACAGTAAGTGAAAATGGTGATCACCTAAGCACATGGATGAGACGTGAGCACAGTTATGGCAGAGAAGTTTCTCCGCACCA GAATTATCCACAGCAACTTGGCTGAGCCCCACTACACACAGAGAAATCATCAACCTGACTTAAGAGTTTTCAAGATGTCAACTTCAGGCT GATCAGCAGATGGGATGTGAAAAATACTACCCTATTCTATCATTTGCTGTTGCTTGCTGAACTGTGAAGAACTGCATGAACTATATTTAA >91064_91064_12_TJP2-PIP5K1B_TJP2_chr9_71855063_ENST00000539225_PIP5K1B_chr9_71555562_ENST00000541509_length(amino acids)=936AA_BP=884 MKTAQALHRMWIQAVKKLRRWKGRVSPSASSPLVFPNLSSWEGEGSKTILTAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFEN GETSIVISDVLPGGPADGLLQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGR SFRSGYSERSRLNSHGGRSRSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDR SRGRSIDQDYERAYHRAYDPDYERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFV KEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEER RHQYSDYDYHSSSEKLKERPSSREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPN TKMVRFKKGDSVGLRLAGGNDVGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVYRDIL ACGRGDSFFIRSHFECEKETPQSLAFTRGEVFRVVDTLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGDRADFWRMR GQRSGVKKNLRKSREDLTAVVSVSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTAKTEPKDAGSEKSTGVVRLNTV RQIIEQDKHALLDVTPKAVDLLNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTALGSRHRPDLVPST -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for TJP2-PIP5K1B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000265384 | + | 17 | 19 | 1188_1190 | 855.3333333333334 | 994.0 | SCRIB |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000348208 | + | 17 | 21 | 1188_1190 | 855.3333333333334 | 1044.0 | SCRIB |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000377245 | + | 17 | 23 | 1188_1190 | 855.3333333333334 | 1191.0 | SCRIB |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000453658 | + | 18 | 22 | 1188_1190 | 832.3333333333334 | 1021.0 | SCRIB |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000535702 | + | 17 | 22 | 1188_1190 | 859.3333333333334 | 1158.0 | SCRIB |
| Hgene | TJP2 | chr9:71855063 | chr9:71555562 | ENST00000539225 | + | 17 | 23 | 1188_1190 | 886.3333333333334 | 1222.0 | SCRIB |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for TJP2-PIP5K1B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for TJP2-PIP5K1B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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