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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TLE3-TASP1 (FusionGDB2 ID:91122)

Fusion Gene Summary for TLE3-TASP1

check button Fusion gene summary
Fusion gene informationFusion gene name: TLE3-TASP1
Fusion gene ID: 91122
HgeneTgene
Gene symbol

TLE3

TASP1

Gene ID

7090

55617

Gene nameTLE family member 3, transcriptional corepressortaspase 1
SynonymsESG|ESG3|GRG3|HsT18976C20orf13|dJ585I14.2
Cytomap

15q23

20p12.1

Type of geneprotein-codingprotein-coding
Descriptiontransducin-like enhancer protein 3enhancer of split groucho 3enhancer of split groucho-like protein 3transducin like enhancer of split 3transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)transducin-like enhancer of split 3 short isoformthreonine aspartase 1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000317509, ENST00000440567, 
ENST00000442299, ENST00000451782, 
ENST00000539550, ENST00000557907, 
ENST00000557997, ENST00000558201, 
ENST00000558379, ENST00000558939, 
ENST00000559048, ENST00000559929, 
ENST00000560589, ENST00000560939, 
ENST00000559191, ENST00000559574, 
ENST00000337743, ENST00000480436, 
ENST00000544472, ENST00000539805, 
Fusion gene scores* DoF score14 X 14 X 6=117615 X 13 X 7=1365
# samples 1617
** MAII scorelog2(16/1176*10)=-2.877744249949
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/1365*10)=-3.00529429966951
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TLE3 [Title/Abstract] AND TASP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTLE3(70386871)-TASP1(13415801), # samples:1
Anticipated loss of major functional domain due to fusion event.TLE3-TASP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
TLE3-TASP1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across TLE3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TASP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CD-8534-01ATLE3chr15

70386871

-TASP1chr20

13415801

-


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Fusion Gene ORF analysis for TLE3-TASP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000317509ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000317509ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000440567ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000440567ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000442299ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000442299ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000451782ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000451782ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000539550ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000539550ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000557907ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000557907ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000557997ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000557997ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000558201ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000558201ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000558379ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000558379ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000558939ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000558939ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000559048ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000559048ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000559929ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000559929ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000560589ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000560589ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000560939ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-5UTRENST00000560939ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-intronENST00000317509ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-intronENST00000440567ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-intronENST00000442299ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-intronENST00000451782ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-intronENST00000539550ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-intronENST00000557907ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-intronENST00000557997ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-intronENST00000558201ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-intronENST00000558379ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-intronENST00000558939ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-intronENST00000559048ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-intronENST00000559929ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-intronENST00000560589ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-
5CDS-intronENST00000560939ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-
Frame-shiftENST00000539550ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
In-frameENST00000317509ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
In-frameENST00000440567ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
In-frameENST00000442299ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
In-frameENST00000451782ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
In-frameENST00000557907ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
In-frameENST00000557997ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
In-frameENST00000558201ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
In-frameENST00000558379ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
In-frameENST00000558939ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
In-frameENST00000559048ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
In-frameENST00000559929ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
In-frameENST00000560589ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
In-frameENST00000560939ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
intron-3CDSENST00000559191ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
intron-3CDSENST00000559574ENST00000539805TLE3chr15

70386871

-TASP1chr20

13415801

-
intron-5UTRENST00000559191ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
intron-5UTRENST00000559191ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
intron-5UTRENST00000559574ENST00000337743TLE3chr15

70386871

-TASP1chr20

13415801

-
intron-5UTRENST00000559574ENST00000480436TLE3chr15

70386871

-TASP1chr20

13415801

-
intron-intronENST00000559191ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-
intron-intronENST00000559574ENST00000544472TLE3chr15

70386871

-TASP1chr20

13415801

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000558939TLE3chr1570386871-ENST00000539805TASP1chr2013415801-20621612827264187
ENST00000442299TLE3chr1570386871-ENST00000539805TASP1chr2013415801-180313535685187
ENST00000317509TLE3chr1570386871-ENST00000539805TASP1chr2013415801-178613365510184
ENST00000560589TLE3chr1570386871-ENST00000539805TASP1chr2013415801-868418654232140
ENST00000559929TLE3chr1570386871-ENST00000539805TASP1chr2013415801-73728752335162
ENST00000559048TLE3chr1570386871-ENST00000539805TASP1chr2013415801-10035537891263
ENST00000560939TLE3chr1570386871-ENST00000539805TASP1chr2013415801-110065088695263
ENST00000557997TLE3chr1570386871-ENST00000539805TASP1chr2013415801-177413245390180
ENST00000558201TLE3chr1570386871-ENST00000539805TASP1chr2013415801-8363866222207
ENST00000440567TLE3chr1570386871-ENST00000539805TASP1chr2013415801-73628652237161
ENST00000558379TLE3chr1570386871-ENST00000539805TASP1chr2013415801-6842344700157
ENST00000557907TLE3chr1570386871-ENST00000539805TASP1chr2013415801-6842344700157
ENST00000451782TLE3chr1570386871-ENST00000539805TASP1chr2013415801-73028051628162

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000558939ENST00000539805TLE3chr1570386871-TASP1chr2013415801-0.193854360.8061456
ENST00000442299ENST00000539805TLE3chr1570386871-TASP1chr2013415801-0.09002790.90997213
ENST00000317509ENST00000539805TLE3chr1570386871-TASP1chr2013415801-0.099074040.90092593
ENST00000560589ENST00000539805TLE3chr1570386871-TASP1chr2013415801-0.242112710.7578873
ENST00000559929ENST00000539805TLE3chr1570386871-TASP1chr2013415801-0.0246480550.9753519
ENST00000559048ENST00000539805TLE3chr1570386871-TASP1chr2013415801-0.054784980.9452151
ENST00000560939ENST00000539805TLE3chr1570386871-TASP1chr2013415801-0.89046560.10953438
ENST00000557997ENST00000539805TLE3chr1570386871-TASP1chr2013415801-0.207853150.79214686
ENST00000558201ENST00000539805TLE3chr1570386871-TASP1chr2013415801-0.042959650.95704037
ENST00000440567ENST00000539805TLE3chr1570386871-TASP1chr2013415801-0.0212896260.9787104
ENST00000558379ENST00000539805TLE3chr1570386871-TASP1chr2013415801-0.0199787430.9800213
ENST00000557907ENST00000539805TLE3chr1570386871-TASP1chr2013415801-0.0199787430.9800213
ENST00000451782ENST00000539805TLE3chr1570386871-TASP1chr2013415801-0.0236978680.9763022

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Fusion Genomic Features for TLE3-TASP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TLE3-TASP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:70386871/chr20:13415801)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTLE3chr15:70386871chr20:13415801ENST00000317509-420225_22878761.0MotifNuclear localization signal
HgeneTLE3chr15:70386871chr20:13415801ENST00000451782-420225_22878770.0MotifNuclear localization signal
HgeneTLE3chr15:70386871chr20:13415801ENST00000557907-420225_22878765.0MotifNuclear localization signal
HgeneTLE3chr15:70386871chr20:13415801ENST00000557997-420225_22878765.0MotifNuclear localization signal
HgeneTLE3chr15:70386871chr20:13415801ENST00000558939-420225_22878773.0MotifNuclear localization signal
HgeneTLE3chr15:70386871chr20:13415801ENST00000559048-319225_22884773.0MotifNuclear localization signal
HgeneTLE3chr15:70386871chr20:13415801ENST00000317509-420132_19978761.0RegionGP domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000317509-4201_13178761.0RegionQ domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000317509-420200_26878761.0RegionCcN domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000317509-420269_45278761.0RegionSP domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000451782-420132_19978770.0RegionGP domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000451782-4201_13178770.0RegionQ domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000451782-420200_26878770.0RegionCcN domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000451782-420269_45278770.0RegionSP domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000557907-420132_19978765.0RegionGP domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000557907-4201_13178765.0RegionQ domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000557907-420200_26878765.0RegionCcN domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000557907-420269_45278765.0RegionSP domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000557997-420132_19978765.0RegionGP domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000557997-4201_13178765.0RegionQ domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000557997-420200_26878765.0RegionCcN domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000557997-420269_45278765.0RegionSP domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000558939-420132_19978773.0RegionGP domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000558939-4201_13178773.0RegionQ domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000558939-420200_26878773.0RegionCcN domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000558939-420269_45278773.0RegionSP domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000559048-319132_19984773.0RegionGP domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000559048-3191_13184773.0RegionQ domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000559048-319200_26884773.0RegionCcN domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000559048-319269_45284773.0RegionSP domain
HgeneTLE3chr15:70386871chr20:13415801ENST00000317509-420484_52278761.0RepeatNote=WD 1
HgeneTLE3chr15:70386871chr20:13415801ENST00000317509-420530_56978761.0RepeatNote=WD 2
HgeneTLE3chr15:70386871chr20:13415801ENST00000317509-420574_61378761.0RepeatNote=WD 3
HgeneTLE3chr15:70386871chr20:13415801ENST00000317509-420616_65578761.0RepeatNote=WD 4
HgeneTLE3chr15:70386871chr20:13415801ENST00000317509-420657_69678761.0RepeatNote=WD 5
HgeneTLE3chr15:70386871chr20:13415801ENST00000317509-420698_73778761.0RepeatNote=WD 6
HgeneTLE3chr15:70386871chr20:13415801ENST00000317509-420739_77178761.0RepeatNote=WD 7
HgeneTLE3chr15:70386871chr20:13415801ENST00000451782-420484_52278770.0RepeatNote=WD 1
HgeneTLE3chr15:70386871chr20:13415801ENST00000451782-420530_56978770.0RepeatNote=WD 2
HgeneTLE3chr15:70386871chr20:13415801ENST00000451782-420574_61378770.0RepeatNote=WD 3
HgeneTLE3chr15:70386871chr20:13415801ENST00000451782-420616_65578770.0RepeatNote=WD 4
HgeneTLE3chr15:70386871chr20:13415801ENST00000451782-420657_69678770.0RepeatNote=WD 5
HgeneTLE3chr15:70386871chr20:13415801ENST00000451782-420698_73778770.0RepeatNote=WD 6
HgeneTLE3chr15:70386871chr20:13415801ENST00000451782-420739_77178770.0RepeatNote=WD 7
HgeneTLE3chr15:70386871chr20:13415801ENST00000557907-420484_52278765.0RepeatNote=WD 1
HgeneTLE3chr15:70386871chr20:13415801ENST00000557907-420530_56978765.0RepeatNote=WD 2
HgeneTLE3chr15:70386871chr20:13415801ENST00000557907-420574_61378765.0RepeatNote=WD 3
HgeneTLE3chr15:70386871chr20:13415801ENST00000557907-420616_65578765.0RepeatNote=WD 4
HgeneTLE3chr15:70386871chr20:13415801ENST00000557907-420657_69678765.0RepeatNote=WD 5
HgeneTLE3chr15:70386871chr20:13415801ENST00000557907-420698_73778765.0RepeatNote=WD 6
HgeneTLE3chr15:70386871chr20:13415801ENST00000557907-420739_77178765.0RepeatNote=WD 7
HgeneTLE3chr15:70386871chr20:13415801ENST00000557997-420484_52278765.0RepeatNote=WD 1
HgeneTLE3chr15:70386871chr20:13415801ENST00000557997-420530_56978765.0RepeatNote=WD 2
HgeneTLE3chr15:70386871chr20:13415801ENST00000557997-420574_61378765.0RepeatNote=WD 3
HgeneTLE3chr15:70386871chr20:13415801ENST00000557997-420616_65578765.0RepeatNote=WD 4
HgeneTLE3chr15:70386871chr20:13415801ENST00000557997-420657_69678765.0RepeatNote=WD 5
HgeneTLE3chr15:70386871chr20:13415801ENST00000557997-420698_73778765.0RepeatNote=WD 6
HgeneTLE3chr15:70386871chr20:13415801ENST00000557997-420739_77178765.0RepeatNote=WD 7
HgeneTLE3chr15:70386871chr20:13415801ENST00000558939-420484_52278773.0RepeatNote=WD 1
HgeneTLE3chr15:70386871chr20:13415801ENST00000558939-420530_56978773.0RepeatNote=WD 2
HgeneTLE3chr15:70386871chr20:13415801ENST00000558939-420574_61378773.0RepeatNote=WD 3
HgeneTLE3chr15:70386871chr20:13415801ENST00000558939-420616_65578773.0RepeatNote=WD 4
HgeneTLE3chr15:70386871chr20:13415801ENST00000558939-420657_69678773.0RepeatNote=WD 5
HgeneTLE3chr15:70386871chr20:13415801ENST00000558939-420698_73778773.0RepeatNote=WD 6
HgeneTLE3chr15:70386871chr20:13415801ENST00000558939-420739_77178773.0RepeatNote=WD 7
HgeneTLE3chr15:70386871chr20:13415801ENST00000559048-319484_52284773.0RepeatNote=WD 1
HgeneTLE3chr15:70386871chr20:13415801ENST00000559048-319530_56984773.0RepeatNote=WD 2
HgeneTLE3chr15:70386871chr20:13415801ENST00000559048-319574_61384773.0RepeatNote=WD 3
HgeneTLE3chr15:70386871chr20:13415801ENST00000559048-319616_65584773.0RepeatNote=WD 4
HgeneTLE3chr15:70386871chr20:13415801ENST00000559048-319657_69684773.0RepeatNote=WD 5
HgeneTLE3chr15:70386871chr20:13415801ENST00000559048-319698_73784773.0RepeatNote=WD 6
HgeneTLE3chr15:70386871chr20:13415801ENST00000559048-319739_77184773.0RepeatNote=WD 7


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Fusion Gene Sequence for TLE3-TASP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>91122_91122_1_TLE3-TASP1_TLE3_chr15_70386871_ENST00000317509_TASP1_chr20_13415801_ENST00000539805_length(transcript)=1786nt_BP=1336nt
GCTCTCGCGGCAGTTCAGACCTCGTGCTCGTCCCCTTCGCCTGTCTGTGTGTGGTATCCGTAGGTCCGGGGCACTTTTTTTTTTGGTGTG
TGTGTGTGTGCGTGCGCGCGTGTGTGTGTGTTGGGTGTGTGTGTTTTGGGGGTTTGCCGGGGCGCGGAGAGGAGAGCCGGGCCGAGGGGA
AGGAAGGAAGCCGTAGAGCTCCCCGGTCTCGGGCTGCGTCTCCCCTCCAGCGCTCTCCTGCCTGTGCGCTCCGACGCGGCAGCGGCGGTG
GCGCTGAGCGCTCCTCGGTGGGGACGCGGTGCTCAAGCTGGGAGCAGCGAGAACCCTTTGCGGAGGCTTCCCGTGCCCGCTGGACTTAGG
ATGCCAGGGCGTTTGATTTGCACCTACTGAGCCCGGAGTTCCTCCCCGGCCCTGGGAAGGGCTTGCAGCGGCGGCGGCGGCGGCGGCAGC
GGCAGTAGCAGACGGAACAGCAGGCTCTCCTCTCCGAGGGGGGGCGTCGAAGCGCCCGCGCCGGGCTCCCGCCCTCACCCTCCGGCGCTC
CTGCGGCCCCAAGCCACCACCTCGTAGCCCGCCTCCTTCCTCTTCTCGCCGCGAGCCCCAGGCCCGGACGCCTCTAGGATCGGACCCGCG
CGCCCCGGATGCTTGGGGCTGCCCCGGCGCGCCCCCCTACAGGCGCGACCCGCTGAGTGACCCGGAGGGGGCCCGAGCTCGCCCCAGGAG
GGGCCCCCGGCCTCGGGACCCCGCGCCGGACCTGCTGGGGAGCCGACGATGTCCGCGCAGTCCCAGGCATTGACGCGCTCGACGCAGCCC
AGGGAAGGCGGCCGGCCGCTGCCCGCCGAGCCCTAGGCGCACAAAGCCCGCGCCCGCCGCCCGGCCCCGGCGCCCGCCGACGACTTTGCC
GCCTGCTCCGCGGCTCTTTGTCTCCACTTGGGGCGGGCGCCCGACTCTGGGATTTCGCTGCGAGAACGAGCTGGGGGGGCCGGGGGCGAG
CTCTCGGTTTCCCGGCCGCCCCCCGCTCGGGCTCGGCTCCCCCCTCCCCCGCACCTCCCCGGCCCGGGCTCTCGGCGCTTCCACGCTCTC
GGAATCACGACCCCTCCCTGCCATGTATCCGCAGGGCAGACATCCGGCTCCCCATCAACCCGGGCAGCCGGGATTTAAATTCACGGTGGC
TGAGTCTTGTGACAGGATCAAAGACGAATTCCAGTTCCTGCAAGCTCAGTATCACAGCCTCAAAGTGGAGTACGACAAGCTGGCAAACGA
GAAGACGGAGATGCAGCGCCATTATGTGATGTACTATGAGATGTCCTATGGCTTGAACATTGAAATGCACAAGCAGGTTCACCTTTCCTT
GCCAGTGAAGATGGCGTGCTTGGCGGAGTGATTGTCCTCCGTTCATGCAGATGTTCTGCCGAGCCTGACTCCTCCCAAAATAAGCAGACA
CTTCTAGTGGAATTTCTGTGGAGCCACACGACGGAGAGCATGTGTGTCGGATATATGTCAGCCCAGGATGGGAAAGCCAAGACTCACATT
TCAAGACTTCCTCCTGGTGCGGTGGCAGGACAGTCTGTGGCAATCGAAGTTGGCCAGCGCAGAAGCTTATTGAATTTATTTACCTTTTCA
GAGTTTCCCTTTAAGCACTACTTTTGCCTCATCCTACAAATTTTGGTGGCTGTGGACCTGGCAAAAACTACATTTCCCAGCATCCACTTC

>91122_91122_1_TLE3-TASP1_TLE3_chr15_70386871_ENST00000317509_TASP1_chr20_13415801_ENST00000539805_length(amino acids)=184AA_BP=
MGPQERRRVRAGARRGRFDAPPRRGEPAVPSATAAAAAAAAAASPSQGRGGTPGSVGANQTPWHPKSSGHGKPPQRVLAAPSLSTASPPR
SAQRHRRCRVGAHRQESAGGETQPETGELYGFLPSPRPGSPLRAPANPQNTHTQHTHTRARTHTHTKKKSAPDLRIPHTDRRRGRARGLN

--------------------------------------------------------------
>91122_91122_2_TLE3-TASP1_TLE3_chr15_70386871_ENST00000440567_TASP1_chr20_13415801_ENST00000539805_length(transcript)=736nt_BP=286nt
ATTTAAGCATCTATCATGGCAGGGTAAACGAGGCAGTTTATCTGGCACCTCCATTTTGCTTGTTGCTACCTTTATGGCTCCCCATCAACC
CGGGCAGCCGGGATTTAAATTCACGGTGGCTGAGTCTTGTGACAGGATCAAAGACGAATTCCAGTTCCTGCAAGCTCAGTATCACAGCCT
CAAAGTGGAGTACGACAAGCTGGCAAACGAGAAGACGGAGATGCAGCGCCATTATGTGATGTACTATGAGATGTCCTATGGCTTGAACAT
TGAAATGCACAAGCAGGTTCACCTTTCCTTGCCAGTGAAGATGGCGTGCTTGGCGGAGTGATTGTCCTCCGTTCATGCAGATGTTCTGCC
GAGCCTGACTCCTCCCAAAATAAGCAGACACTTCTAGTGGAATTTCTGTGGAGCCACACGACGGAGAGCATGTGTGTCGGATATATGTCA
GCCCAGGATGGGAAAGCCAAGACTCACATTTCAAGACTTCCTCCTGGTGCGGTGGCAGGACAGTCTGTGGCAATCGAAGTTGGCCAGCGC
AGAAGCTTATTGAATTTATTTACCTTTTCAGAGTTTCCCTTTAAGCACTACTTTTGCCTCATCCTACAAATTTTGGTGGCTGTGGACCTG
GCAAAAACTACATTTCCCAGCATCCACTTCATCTGAGTGCGACCATATGACACAATTCTGCCCCATGAGGAGTAAGTGGAAGGTTCTGGA

>91122_91122_2_TLE3-TASP1_TLE3_chr15_70386871_ENST00000440567_TASP1_chr20_13415801_ENST00000539805_length(amino acids)=161AA_BP=1
MPQTVLPPHQEEVLKCESWLSHPGLTYIRHTCSPSCGSTEIPLEVSAYFGRSQARQNICMNGGQSLRQARHLHWQGKVNLLVHFNVQAIG

--------------------------------------------------------------
>91122_91122_3_TLE3-TASP1_TLE3_chr15_70386871_ENST00000442299_TASP1_chr20_13415801_ENST00000539805_length(transcript)=1803nt_BP=1353nt
AGTCCCTATTTGGAACTGCTCTCGCGGCAGTTCAGACCTCGTGCTCGTCCCCTTCGCCTGTCTGTGTGTGGTATCCGTAGGTCCGGGGCA
CTTTTTTTTTTGGTGTGTGTGTGTGTGCGTGCGCGCGTGTGTGTGTGTTGGGTGTGTGTGTTTTGGGGGTTTGCCGGGGCGCGGAGAGGA
GAGCCGGGCCGAGGGGAAGGAAGGAAGCCGTAGAGCTCCCCGGTCTCGGGCTGCGTCTCCCCTCCAGCGCTCTCCTGCCTGTGCGCTCCG
ACGCGGCAGCGGCGGTGGCGCTGAGCGCTCCTCGGTGGGGACGCGGTGCTCAAGCTGGGAGCAGCGAGAACCCTTTGCGGAGGCTTCCCG
TGCCCGCTGGACTTAGGATGCCAGGGCGTTTGATTTGCACCTACTGAGCCCGGAGTTCCTCCCCGGCCCTGGGAAGGGCTTGCAGCGGCG
GCGGCGGCGGCGGCAGCGGCAGTAGCAGACGGAACAGCAGGCTCTCCTCTCCGAGGGGGGGCGTCGAAGCGCCCGCGCCGGGCTCCCGCC
CTCACCCTCCGGCGCTCCTGCGGCCCCAAGCCACCACCTCGTAGCCCGCCTCCTTCCTCTTCTCGCCGCGAGCCCCAGGCCCGGACGCCT
CTAGGATCGGACCCGCGCGCCCCGGATGCTTGGGGCTGCCCCGGCGCGCCCCCCTACAGGCGCGACCCGCTGAGTGACCCGGAGGGGGCC
CGAGCTCGCCCCAGGAGGGGCCCCCGGCCTCGGGACCCCGCGCCGGACCTGCTGGGGAGCCGACGATGTCCGCGCAGTCCCAGGCATTGA
CGCGCTCGACGCAGCCCAGGGAAGGCGGCCGGCCGCTGCCCGCCGAGCCCTAGGCGCACAAAGCCCGCGCCCGCCGCCCGGCCCCGGCGC
CCGCCGACGACTTTGCCGCCTGCTCCGCGGCTCTTTGTCTCCACTTGGGGCGGGCGCCCGACTCTGGGATTTCGCTGCGAGAACGAGCTG
GGGGGGCCGGGGGCGAGCTCTCGGTTTCCCGGCCGCCCCCCGCTCGGGCTCGGCTCCCCCCTCCCCCGCACCTCCCCGGCCCGGGCTCTC
GGCGCTTCCACGCTCTCGGAATCACGACCCCTCCCTGCCATGTATCCGCAGGGCAGACATCCGGCTCCCCATCAACCCGGGCAGCCGGGA
TTTAAATTCACGGTGGCTGAGTCTTGTGACAGGATCAAAGACGAATTCCAGTTCCTGCAAGCTCAGTATCACAGCCTCAAAGTGGAGTAC
GACAAGCTGGCAAACGAGAAGACGGAGATGCAGCGCCATTATGTGATGTACTATGAGATGTCCTATGGCTTGAACATTGAAATGCACAAG
CAGGTTCACCTTTCCTTGCCAGTGAAGATGGCGTGCTTGGCGGAGTGATTGTCCTCCGTTCATGCAGATGTTCTGCCGAGCCTGACTCCT
CCCAAAATAAGCAGACACTTCTAGTGGAATTTCTGTGGAGCCACACGACGGAGAGCATGTGTGTCGGATATATGTCAGCCCAGGATGGGA
AAGCCAAGACTCACATTTCAAGACTTCCTCCTGGTGCGGTGGCAGGACAGTCTGTGGCAATCGAAGTTGGCCAGCGCAGAAGCTTATTGA
ATTTATTTACCTTTTCAGAGTTTCCCTTTAAGCACTACTTTTGCCTCATCCTACAAATTTTGGTGGCTGTGGACCTGGCAAAAACTACAT
TTCCCAGCATCCACTTCATCTGAGTGCGACCATATGACACAATTCTGCCCCATGAGGAGTAAGTGGAAGGTTCTGGACAGAACTGCTGCA

>91122_91122_3_TLE3-TASP1_TLE3_chr15_70386871_ENST00000442299_TASP1_chr20_13415801_ENST00000539805_length(amino acids)=187AA_BP=
MGPQERRRVRAGARRGRFDAPPRRGEPAVPSATAAAAAAAAAASPSQGRGGTPGSVGANQTPWHPKSSGHGKPPQRVLAAPSLSTASPPR
SAQRHRRCRVGAHRQESAGGETQPETGELYGFLPSPRPGSPLRAPANPQNTHTQHTHTRARTHTHTKKKSAPDLRIPHTDRRRGRARGLN

--------------------------------------------------------------
>91122_91122_4_TLE3-TASP1_TLE3_chr15_70386871_ENST00000451782_TASP1_chr20_13415801_ENST00000539805_length(transcript)=730nt_BP=280nt
GGCTCTCGGCGCTTCCACGCTCTCGGAATCACGACCCCTCCCTGCCATGTATCCGCAGGGCAGACATCCGGCTCCCCATCAACCCGGGCA
GCCGGGATTTAAATTCACGGTGGCTGAGTCTTGTGACAGGATCAAAGACGAATTCCAGTTCCTGCAAGCTCAGTATCACAGCCTCAAAGT
GGAGTACGACAAGCTGGCAAACGAGAAGACGGAGATGCAGCGCCATTATGTGATGTACTATGAGATGTCCTATGGCTTGAACATTGAAAT
GCACAAGCAGGTTCACCTTTCCTTGCCAGTGAAGATGGCGTGCTTGGCGGAGTGATTGTCCTCCGTTCATGCAGATGTTCTGCCGAGCCT
GACTCCTCCCAAAATAAGCAGACACTTCTAGTGGAATTTCTGTGGAGCCACACGACGGAGAGCATGTGTGTCGGATATATGTCAGCCCAG
GATGGGAAAGCCAAGACTCACATTTCAAGACTTCCTCCTGGTGCGGTGGCAGGACAGTCTGTGGCAATCGAAGTTGGCCAGCGCAGAAGC
TTATTGAATTTATTTACCTTTTCAGAGTTTCCCTTTAAGCACTACTTTTGCCTCATCCTACAAATTTTGGTGGCTGTGGACCTGGCAAAA
ACTACATTTCCCAGCATCCACTTCATCTGAGTGCGACCATATGACACAATTCTGCCCCATGAGGAGTAAGTGGAAGGTTCTGGACAGAAC

>91122_91122_4_TLE3-TASP1_TLE3_chr15_70386871_ENST00000451782_TASP1_chr20_13415801_ENST00000539805_length(amino acids)=162AA_BP=1
MPQTVLPPHQEEVLKCESWLSHPGLTYIRHTCSPSCGSTEIPLEVSAYFGRSQARQNICMNGGQSLRQARHLHWQGKVNLLVHFNVQAIG

--------------------------------------------------------------
>91122_91122_5_TLE3-TASP1_TLE3_chr15_70386871_ENST00000557907_TASP1_chr20_13415801_ENST00000539805_length(transcript)=684nt_BP=234nt
ATGTATCCGCAGGGCAGACATCCGGCTCCCCATCAACCCGGGCAGCCGGGATTTAAATTCACGGTGGCTGAGTCTTGTGACAGGATCAAA
GACGAATTCCAGTTCCTGCAAGCTCAGTATCACAGCCTCAAAGTGGAGTACGACAAGCTGGCAAACGAGAAGACGGAGATGCAGCGCCAT
TATGTGATGTACTATGAGATGTCCTATGGCTTGAACATTGAAATGCACAAGCAGGTTCACCTTTCCTTGCCAGTGAAGATGGCGTGCTTG
GCGGAGTGATTGTCCTCCGTTCATGCAGATGTTCTGCCGAGCCTGACTCCTCCCAAAATAAGCAGACACTTCTAGTGGAATTTCTGTGGA
GCCACACGACGGAGAGCATGTGTGTCGGATATATGTCAGCCCAGGATGGGAAAGCCAAGACTCACATTTCAAGACTTCCTCCTGGTGCGG
TGGCAGGACAGTCTGTGGCAATCGAAGTTGGCCAGCGCAGAAGCTTATTGAATTTATTTACCTTTTCAGAGTTTCCCTTTAAGCACTACT
TTTGCCTCATCCTACAAATTTTGGTGGCTGTGGACCTGGCAAAAACTACATTTCCCAGCATCCACTTCATCTGAGTGCGACCATATGACA

>91122_91122_5_TLE3-TASP1_TLE3_chr15_70386871_ENST00000557907_TASP1_chr20_13415801_ENST00000539805_length(amino acids)=157AA_BP=1
MPQTVLPPHQEEVLKCESWLSHPGLTYIRHTCSPSCGSTEIPLEVSAYFGRSQARQNICMNGGQSLRQARHLHWQGKVNLLVHFNVQAIG

--------------------------------------------------------------
>91122_91122_6_TLE3-TASP1_TLE3_chr15_70386871_ENST00000557997_TASP1_chr20_13415801_ENST00000539805_length(transcript)=1774nt_BP=1324nt
GTTCAGACCTCGTGCTCGTCCCCTTCGCCTGTCTGTGTGTGGTATCCGTAGGTCCGGGGCACTTTTTTTTTTGGTGTGTGTGTGTGTGCG
TGCGCGCGTGTGTGTGTGTTGGGTGTGTGTGTTTTGGGGGTTTGCCGGGGCGCGGAGAGGAGAGCCGGGCCGAGGGGAAGGAAGGAAGCC
GTAGAGCTCCCCGGTCTCGGGCTGCGTCTCCCCTCCAGCGCTCTCCTGCCTGTGCGCTCCGACGCGGCAGCGGCGGTGGCGCTGAGCGCT
CCTCGGTGGGGACGCGGTGCTCAAGCTGGGAGCAGCGAGAACCCTTTGCGGAGGCTTCCCGTGCCCGCTGGACTTAGGATGCCAGGGCGT
TTGATTTGCACCTACTGAGCCCGGAGTTCCTCCCCGGCCCTGGGAAGGGCTTGCAGCGGCGGCGGCGGCGGCGGCAGCGGCAGTAGCAGA
CGGAACAGCAGGCTCTCCTCTCCGAGGGGGGGCGTCGAAGCGCCCGCGCCGGGCTCCCGCCCTCACCCTCCGGCGCTCCTGCGGCCCCAA
GCCACCACCTCGTAGCCCGCCTCCTTCCTCTTCTCGCCGCGAGCCCCAGGCCCGGACGCCTCTAGGATCGGACCCGCGCGCCCCGGATGC
TTGGGGCTGCCCCGGCGCGCCCCCCTACAGGCGCGACCCGCTGAGTGACCCGGAGGGGGCCCGAGCTCGCCCCAGGAGGGGCCCCCGGCC
TCGGGACCCCGCGCCGGACCTGCTGGGGAGCCGACGATGTCCGCGCAGTCCCAGGCATTGACGCGCTCGACGCAGCCCAGGGAAGGCGGC
CGGCCGCTGCCCGCCGAGCCCTAGGCGCACAAAGCCCGCGCCCGCCGCCCGGCCCCGGCGCCCGCCGACGACTTTGCCGCCTGCTCCGCG
GCTCTTTGTCTCCACTTGGGGCGGGCGCCCGACTCTGGGATTTCGCTGCGAGAACGAGCTGGGGGGGCCGGGGGCGAGCTCTCGGTTTCC
CGGCCGCCCCCCGCTCGGGCTCGGCTCCCCCCTCCCCCGCACCTCCCCGGCCCGGGCTCTCGGCGCTTCCACGCTCTCGGAATCACGACC
CCTCCCTGCCATGTATCCGCAGGGCAGACATCCGGCTCCCCATCAACCCGGGCAGCCGGGATTTAAATTCACGGTGGCTGAGTCTTGTGA
CAGGATCAAAGACGAATTCCAGTTCCTGCAAGCTCAGTATCACAGCCTCAAAGTGGAGTACGACAAGCTGGCAAACGAGAAGACGGAGAT
GCAGCGCCATTATGTGATGTACTATGAGATGTCCTATGGCTTGAACATTGAAATGCACAAGCAGGTTCACCTTTCCTTGCCAGTGAAGAT
GGCGTGCTTGGCGGAGTGATTGTCCTCCGTTCATGCAGATGTTCTGCCGAGCCTGACTCCTCCCAAAATAAGCAGACACTTCTAGTGGAA
TTTCTGTGGAGCCACACGACGGAGAGCATGTGTGTCGGATATATGTCAGCCCAGGATGGGAAAGCCAAGACTCACATTTCAAGACTTCCT
CCTGGTGCGGTGGCAGGACAGTCTGTGGCAATCGAAGTTGGCCAGCGCAGAAGCTTATTGAATTTATTTACCTTTTCAGAGTTTCCCTTT
AAGCACTACTTTTGCCTCATCCTACAAATTTTGGTGGCTGTGGACCTGGCAAAAACTACATTTCCCAGCATCCACTTCATCTGAGTGCGA

>91122_91122_6_TLE3-TASP1_TLE3_chr15_70386871_ENST00000557997_TASP1_chr20_13415801_ENST00000539805_length(amino acids)=180AA_BP=
MGPQERRRVRAGARRGRFDAPPRRGEPAVPSATAAAAAAAAAASPSQGRGGTPGSVGANQTPWHPKSSGHGKPPQRVLAAPSLSTASPPR
SAQRHRRCRVGAHRQESAGGETQPETGELYGFLPSPRPGSPLRAPANPQNTHTQHTHTRARTHTHTKKKSAPDLRIPHTDRRRGRARGLN

--------------------------------------------------------------
>91122_91122_7_TLE3-TASP1_TLE3_chr15_70386871_ENST00000558201_TASP1_chr20_13415801_ENST00000539805_length(transcript)=836nt_BP=386nt
GGGGAGAGATGGGGCGCCCCCCCTCCGCCCCGTCGGAGAGCTGAGAAACTTGCTGGGAAGGTTCTGGGCTGAGGGTGGCCTCTTTTGGTT
GGGCGCCGTTGGGGAGGGGCCGGGGCCGCTCTGAGCGCGGTCTCATGCCCCCGCCCCCTCCCCTGTCTTGTCTTCGCGGGCTCCAGGCTC
CCCATCAACCCGGGCAGCCGGGATTTAAATTCACGGTGGCTGAGTCTTGTGACAGGATCAAAGACGAATTCCAGTTCCTGCAAGCTCAGT
ATCACAGCCTCAAAGTGGAGTACGACAAGCTGGCAAACGAGAAGACGGAGATGCAGCGCCATTATGTGATGTACTATGAGATGTCCTATG
GCTTGAACATTGAAATGCACAAGCAGGTTCACCTTTCCTTGCCAGTGAAGATGGCGTGCTTGGCGGAGTGATTGTCCTCCGTTCATGCAG
ATGTTCTGCCGAGCCTGACTCCTCCCAAAATAAGCAGACACTTCTAGTGGAATTTCTGTGGAGCCACACGACGGAGAGCATGTGTGTCGG
ATATATGTCAGCCCAGGATGGGAAAGCCAAGACTCACATTTCAAGACTTCCTCCTGGTGCGGTGGCAGGACAGTCTGTGGCAATCGAAGT
TGGCCAGCGCAGAAGCTTATTGAATTTATTTACCTTTTCAGAGTTTCCCTTTAAGCACTACTTTTGCCTCATCCTACAAATTTTGGTGGC
TGTGGACCTGGCAAAAACTACATTTCCCAGCATCCACTTCATCTGAGTGCGACCATATGACACAATTCTGCCCCATGAGGAGTAAGTGGA

>91122_91122_7_TLE3-TASP1_TLE3_chr15_70386871_ENST00000558201_TASP1_chr20_13415801_ENST00000539805_length(amino acids)=207AA_BP=1
MPQTVLPPHQEEVLKCESWLSHPGLTYIRHTCSPSCGSTEIPLEVSAYFGRSQARQNICMNGGQSLRQARHLHWQGKVNLLVHFNVQAIG
HLIVHHIMALHLRLLVCQLVVLHFEAVILSLQELEFVFDPVTRLSHREFKSRLPGLMGSLEPAKTRQGRGRGHETALRAAPAPPQRRPTK

--------------------------------------------------------------
>91122_91122_8_TLE3-TASP1_TLE3_chr15_70386871_ENST00000558379_TASP1_chr20_13415801_ENST00000539805_length(transcript)=684nt_BP=234nt
ATGTATCCGCAGGGCAGACATCCGGCTCCCCATCAACCCGGGCAGCCGGGATTTAAATTCACGGTGGCTGAGTCTTGTGACAGGATCAAA
GACGAATTCCAGTTCCTGCAAGCTCAGTATCACAGCCTCAAAGTGGAGTACGACAAGCTGGCAAACGAGAAGACGGAGATGCAGCGCCAT
TATGTGATGTACTATGAGATGTCCTATGGCTTGAACATTGAAATGCACAAGCAGGTTCACCTTTCCTTGCCAGTGAAGATGGCGTGCTTG
GCGGAGTGATTGTCCTCCGTTCATGCAGATGTTCTGCCGAGCCTGACTCCTCCCAAAATAAGCAGACACTTCTAGTGGAATTTCTGTGGA
GCCACACGACGGAGAGCATGTGTGTCGGATATATGTCAGCCCAGGATGGGAAAGCCAAGACTCACATTTCAAGACTTCCTCCTGGTGCGG
TGGCAGGACAGTCTGTGGCAATCGAAGTTGGCCAGCGCAGAAGCTTATTGAATTTATTTACCTTTTCAGAGTTTCCCTTTAAGCACTACT
TTTGCCTCATCCTACAAATTTTGGTGGCTGTGGACCTGGCAAAAACTACATTTCCCAGCATCCACTTCATCTGAGTGCGACCATATGACA

>91122_91122_8_TLE3-TASP1_TLE3_chr15_70386871_ENST00000558379_TASP1_chr20_13415801_ENST00000539805_length(amino acids)=157AA_BP=1
MPQTVLPPHQEEVLKCESWLSHPGLTYIRHTCSPSCGSTEIPLEVSAYFGRSQARQNICMNGGQSLRQARHLHWQGKVNLLVHFNVQAIG

--------------------------------------------------------------
>91122_91122_9_TLE3-TASP1_TLE3_chr15_70386871_ENST00000558939_TASP1_chr20_13415801_ENST00000539805_length(transcript)=2062nt_BP=1612nt
TATAATATATATCTATTTATTATATGTCTTTCGGTTAATTCCTGATCTGAGGAGCGCTGTTTTTCACTCCCATGCGAAAGTCACCAGCGG
GTAGGGCCTGATTGCTACTTTTCATGCATAGTTTTAGACACAAGAGGGCATTGTGACGTCGCGCCCAGCGGCACCCAGTCGTAGGCCGAG
TCCCGCAGCCCCACGTGGGGGCCCCGCGCTCCCATTGGCCAGCGCCGGACGAAGCTGCCACATTATTTTGTTACTTTTCAGTCCCTATTT
GGAACTGCTCTCGCGGCAGTTCAGACCTCGTGCTCGTCCCCTTCGCCTGTCTGTGTGTGGTATCCGTAGGTCCGGGGCACTTTTTTTTTT
GGTGTGTGTGTGTGTGCGTGCGCGCGTGTGTGTGTGTTGGGTGTGTGTGTTTTGGGGGTTTGCCGGGGCGCGGAGAGGAGAGCCGGGCCG
AGGGGAAGGAAGGAAGCCGTAGAGCTCCCCGGTCTCGGGCTGCGTCTCCCCTCCAGCGCTCTCCTGCCTGTGCGCTCCGACGCGGCAGCG
GCGGTGGCGCTGAGCGCTCCTCGGTGGGGACGCGGTGCTCAAGCTGGGAGCAGCGAGAACCCTTTGCGGAGGCTTCCCGTGCCCGCTGGA
CTTAGGATGCCAGGGCGTTTGATTTGCACCTACTGAGCCCGGAGTTCCTCCCCGGCCCTGGGAAGGGCTTGCAGCGGCGGCGGCGGCGGC
GGCAGCGGCAGTAGCAGACGGAACAGCAGGCTCTCCTCTCCGAGGGGGGGCGTCGAAGCGCCCGCGCCGGGCTCCCGCCCTCACCCTCCG
GCGCTCCTGCGGCCCCAAGCCACCACCTCGTAGCCCGCCTCCTTCCTCTTCTCGCCGCGAGCCCCAGGCCCGGACGCCTCTAGGATCGGA
CCCGCGCGCCCCGGATGCTTGGGGCTGCCCCGGCGCGCCCCCCTACAGGCGCGACCCGCTGAGTGACCCGGAGGGGGCCCGAGCTCGCCC
CAGGAGGGGCCCCCGGCCTCGGGACCCCGCGCCGGACCTGCTGGGGAGCCGACGATGTCCGCGCAGTCCCAGGCATTGACGCGCTCGACG
CAGCCCAGGGAAGGCGGCCGGCCGCTGCCCGCCGAGCCCTAGGCGCACAAAGCCCGCGCCCGCCGCCCGGCCCCGGCGCCCGCCGACGAC
TTTGCCGCCTGCTCCGCGGCTCTTTGTCTCCACTTGGGGCGGGCGCCCGACTCTGGGATTTCGCTGCGAGAACGAGCTGGGGGGGCCGGG
GGCGAGCTCTCGGTTTCCCGGCCGCCCCCCGCTCGGGCTCGGCTCCCCCCTCCCCCGCACCTCCCCGGCCCGGGCTCTCGGCGCTTCCAC
GCTCTCGGAATCACGACCCCTCCCTGCCATGTATCCGCAGGGCAGACATCCGGCTCCCCATCAACCCGGGCAGCCGGGATTTAAATTCAC
GGTGGCTGAGTCTTGTGACAGGATCAAAGACGAATTCCAGTTCCTGCAAGCTCAGTATCACAGCCTCAAAGTGGAGTACGACAAGCTGGC
AAACGAGAAGACGGAGATGCAGCGCCATTATGTGATGTACTATGAGATGTCCTATGGCTTGAACATTGAAATGCACAAGCAGGTTCACCT
TTCCTTGCCAGTGAAGATGGCGTGCTTGGCGGAGTGATTGTCCTCCGTTCATGCAGATGTTCTGCCGAGCCTGACTCCTCCCAAAATAAG
CAGACACTTCTAGTGGAATTTCTGTGGAGCCACACGACGGAGAGCATGTGTGTCGGATATATGTCAGCCCAGGATGGGAAAGCCAAGACT
CACATTTCAAGACTTCCTCCTGGTGCGGTGGCAGGACAGTCTGTGGCAATCGAAGTTGGCCAGCGCAGAAGCTTATTGAATTTATTTACC
TTTTCAGAGTTTCCCTTTAAGCACTACTTTTGCCTCATCCTACAAATTTTGGTGGCTGTGGACCTGGCAAAAACTACATTTCCCAGCATC

>91122_91122_9_TLE3-TASP1_TLE3_chr15_70386871_ENST00000558939_TASP1_chr20_13415801_ENST00000539805_length(amino acids)=187AA_BP=
MGPQERRRVRAGARRGRFDAPPRRGEPAVPSATAAAAAAAAAASPSQGRGGTPGSVGANQTPWHPKSSGHGKPPQRVLAAPSLSTASPPR
SAQRHRRCRVGAHRQESAGGETQPETGELYGFLPSPRPGSPLRAPANPQNTHTQHTHTRARTHTHTKKKSAPDLRIPHTDRRRGRARGLN

--------------------------------------------------------------
>91122_91122_10_TLE3-TASP1_TLE3_chr15_70386871_ENST00000559048_TASP1_chr20_13415801_ENST00000539805_length(transcript)=1003nt_BP=553nt
AATTCCGCGCGAGTGGCGCGGGGGGCTGCTTGTGTTCCAGGGGGAGCTGTTCACGCGGTCCCCGGCCCCGCTCTGAAGTCTCCCAACTCA
CCCGGCTTGTCTCCCGCCCCCGCCTTACTGGGGAGAGGGAGGCCCTTGGTGAAAGGCATGGGAGCCCCGCTGCCGACGGGGAGAGATGGG
GCGCCCCCCCTCCGCCCCGTCGGAGAGCTGAGAAACTTGCTGGGAAGGTTCTGGGCTGAGGGTGGCCTCTTTTGGTTGGGCGCCGTTGGG
GAGGGGCCGGGGCCGCTCTGAGCGCGGTCTCATGCCCCCGCCCCCTCCCCTGTCTTGTCTTCGCGGGCTCCAGGCTCCCCATCAACCCGG
GCAGCCGGGATTTAAATTCACGGTGGCTGAGTCTTGTGACAGGATCAAAGACGAATTCCAGTTCCTGCAAGCTCAGTATCACAGCCTCAA
AGTGGAGTACGACAAGCTGGCAAACGAGAAGACGGAGATGCAGCGCCATTATGTGATGTACTATGAGATGTCCTATGGCTTGAACATTGA
AATGCACAAGCAGGTTCACCTTTCCTTGCCAGTGAAGATGGCGTGCTTGGCGGAGTGATTGTCCTCCGTTCATGCAGATGTTCTGCCGAG
CCTGACTCCTCCCAAAATAAGCAGACACTTCTAGTGGAATTTCTGTGGAGCCACACGACGGAGAGCATGTGTGTCGGATATATGTCAGCC
CAGGATGGGAAAGCCAAGACTCACATTTCAAGACTTCCTCCTGGTGCGGTGGCAGGACAGTCTGTGGCAATCGAAGTTGGCCAGCGCAGA
AGCTTATTGAATTTATTTACCTTTTCAGAGTTTCCCTTTAAGCACTACTTTTGCCTCATCCTACAAATTTTGGTGGCTGTGGACCTGGCA
AAAACTACATTTCCCAGCATCCACTTCATCTGAGTGCGACCATATGACACAATTCTGCCCCATGAGGAGTAAGTGGAAGGTTCTGGACAG

>91122_91122_10_TLE3-TASP1_TLE3_chr15_70386871_ENST00000559048_TASP1_chr20_13415801_ENST00000539805_length(amino acids)=263AA_BP=1
MPQTVLPPHQEEVLKCESWLSHPGLTYIRHTCSPSCGSTEIPLEVSAYFGRSQARQNICMNGGQSLRQARHLHWQGKVNLLVHFNVQAIG
HLIVHHIMALHLRLLVCQLVVLHFEAVILSLQELEFVFDPVTRLSHREFKSRLPGLMGSLEPAKTRQGRGRGHETALRAAPAPPQRRPTK

--------------------------------------------------------------
>91122_91122_11_TLE3-TASP1_TLE3_chr15_70386871_ENST00000559929_TASP1_chr20_13415801_ENST00000539805_length(transcript)=737nt_BP=287nt
CGGCCCGGGCTCTCGGCGCTTCCACGCTCTCGGAATCACGACCCCTCCCTGCCATGTATCCGCAGGGCAGACATCCGGCTCCCCATCAAC
CCGGGCAGCCGGGATTTAAATTCACGGTGGCTGAGTCTTGTGACAGGATCAAAGACGAATTCCAGTTCCTGCAAGCTCAGTATCACAGCC
TCAAAGTGGAGTACGACAAGCTGGCAAACGAGAAGACGGAGATGCAGCGCCATTATGTGATGTACTATGAGATGTCCTATGGCTTGAACA
TTGAAATGCACAAGCAGGTTCACCTTTCCTTGCCAGTGAAGATGGCGTGCTTGGCGGAGTGATTGTCCTCCGTTCATGCAGATGTTCTGC
CGAGCCTGACTCCTCCCAAAATAAGCAGACACTTCTAGTGGAATTTCTGTGGAGCCACACGACGGAGAGCATGTGTGTCGGATATATGTC
AGCCCAGGATGGGAAAGCCAAGACTCACATTTCAAGACTTCCTCCTGGTGCGGTGGCAGGACAGTCTGTGGCAATCGAAGTTGGCCAGCG
CAGAAGCTTATTGAATTTATTTACCTTTTCAGAGTTTCCCTTTAAGCACTACTTTTGCCTCATCCTACAAATTTTGGTGGCTGTGGACCT
GGCAAAAACTACATTTCCCAGCATCCACTTCATCTGAGTGCGACCATATGACACAATTCTGCCCCATGAGGAGTAAGTGGAAGGTTCTGG

>91122_91122_11_TLE3-TASP1_TLE3_chr15_70386871_ENST00000559929_TASP1_chr20_13415801_ENST00000539805_length(amino acids)=162AA_BP=1
MPQTVLPPHQEEVLKCESWLSHPGLTYIRHTCSPSCGSTEIPLEVSAYFGRSQARQNICMNGGQSLRQARHLHWQGKVNLLVHFNVQAIG

--------------------------------------------------------------
>91122_91122_12_TLE3-TASP1_TLE3_chr15_70386871_ENST00000560589_TASP1_chr20_13415801_ENST00000539805_length(transcript)=868nt_BP=418nt
CCGAATGAGGGTCTAGGTCGCGGCGAGCGGGTTCACTCCGGGTTCTGGGTGTCGGGAGCCAGCGTCAGGGTCCTACTCCCCTGCTGCCGT
GATAAGTCCTTTGGCTCGCGGGAAGTTTCGAATTGTTTCACATCCCCCTCCCCACGGCGGGGACCCAAATCCCCCCGCGTCCCCAGGCTG
TGGGATAATGGGGGCGCCCCCGGGGGGGTGTCAGGAAAGTGGAAAAGTGGCTCTAGAGGCCCTTGGGTCGGGGCCTCAGAGGAGGCTGTC
CAGGCGCCACGCCTGAGCCGGCTCCTCCTGCCCTCGCAGCCTCAAAGTGGAGTACGACAAGCTGGCAAACGAGAAGACGGAGATGCAGCG
CCATTATGTGATGTACTATGAGATGTCCTATGGCTTGAACATTGAAATGCACAAGCAGGTTCACCTTTCCTTGCCAGTGAAGATGGCGTG
CTTGGCGGAGTGATTGTCCTCCGTTCATGCAGATGTTCTGCCGAGCCTGACTCCTCCCAAAATAAGCAGACACTTCTAGTGGAATTTCTG
TGGAGCCACACGACGGAGAGCATGTGTGTCGGATATATGTCAGCCCAGGATGGGAAAGCCAAGACTCACATTTCAAGACTTCCTCCTGGT
GCGGTGGCAGGACAGTCTGTGGCAATCGAAGTTGGCCAGCGCAGAAGCTTATTGAATTTATTTACCTTTTCAGAGTTTCCCTTTAAGCAC
TACTTTTGCCTCATCCTACAAATTTTGGTGGCTGTGGACCTGGCAAAAACTACATTTCCCAGCATCCACTTCATCTGAGTGCGACCATAT

>91122_91122_12_TLE3-TASP1_TLE3_chr15_70386871_ENST00000560589_TASP1_chr20_13415801_ENST00000539805_length(amino acids)=140AA_BP=1
MPQTVLPPHQEEVLKCESWLSHPGLTYIRHTCSPSCGSTEIPLEVSAYFGRSQARQNICMNGGQSLRQARHLHWQGKVNLLVHFNVQAIG

--------------------------------------------------------------
>91122_91122_13_TLE3-TASP1_TLE3_chr15_70386871_ENST00000560939_TASP1_chr20_13415801_ENST00000539805_length(transcript)=1100nt_BP=650nt
CATTTTGCTTGTTGCTACCTTTATGGTGTGTGTGTTTGTGTGTGTGCTCTCACACAAAGGGGGATGCGGCCGGGGGGCGCCGTTGAGAGA
GGAGGTTAATTCCGCGCGAGTGGCGCGGGGGGCTGCTTGTGTTCCAGGGGGAGCTGTTCACGCGGTCCCCGGCCCCGCTCTGAAGTCTCC
CAACTCACCCGGCTTGTCTCCCGCCCCCGCCTTACTGGGGAGAGGGAGGCCCTTGGTGAAAGGCATGGGAGCCCCGCTGCCGACGGGGAG
AGATGGGGCGCCCCCCCTCCGCCCCGTCGGAGAGCTGAGAAACTTGCTGGGAAGGTTCTGGGCTGAGGGTGGCCTCTTTTGGTTGGGCGC
CGTTGGGGAGGGGCCGGGGCCGCTCTGAGCGCGGTCTCATGCCCCCGCCCCCTCCCCTGTCTTGTCTTCGCGGGCTCCAGGCTCCCCATC
AACCCGGGCAGCCGGGATTTAAATTCACGGTGGCTGAGTCTTGTGACAGGATCAAAGACGAATTCCAGTTCCTGCAAGCTCAGTATCACA
GCCTCAAAGTGGAGTACGACAAGCTGGCAAACGAGAAGACGGAGATGCAGCGCCATTATGTGATGTACTATGAGATGTCCTATGGCTTGA
ACATTGAAATGCACAAGCAGGTTCACCTTTCCTTGCCAGTGAAGATGGCGTGCTTGGCGGAGTGATTGTCCTCCGTTCATGCAGATGTTC
TGCCGAGCCTGACTCCTCCCAAAATAAGCAGACACTTCTAGTGGAATTTCTGTGGAGCCACACGACGGAGAGCATGTGTGTCGGATATAT
GTCAGCCCAGGATGGGAAAGCCAAGACTCACATTTCAAGACTTCCTCCTGGTGCGGTGGCAGGACAGTCTGTGGCAATCGAAGTTGGCCA
GCGCAGAAGCTTATTGAATTTATTTACCTTTTCAGAGTTTCCCTTTAAGCACTACTTTTGCCTCATCCTACAAATTTTGGTGGCTGTGGA
CCTGGCAAAAACTACATTTCCCAGCATCCACTTCATCTGAGTGCGACCATATGACACAATTCTGCCCCATGAGGAGTAAGTGGAAGGTTC

>91122_91122_13_TLE3-TASP1_TLE3_chr15_70386871_ENST00000560939_TASP1_chr20_13415801_ENST00000539805_length(amino acids)=263AA_BP=1
MPQTVLPPHQEEVLKCESWLSHPGLTYIRHTCSPSCGSTEIPLEVSAYFGRSQARQNICMNGGQSLRQARHLHWQGKVNLLVHFNVQAIG
HLIVHHIMALHLRLLVCQLVVLHFEAVILSLQELEFVFDPVTRLSHREFKSRLPGLMGSLEPAKTRQGRGRGHETALRAAPAPPQRRPTK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TLE3-TASP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TLE3-TASP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TLE3-TASP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource