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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BBX-KPNA4 (FusionGDB2 ID:9120)

Fusion Gene Summary for BBX-KPNA4

check button Fusion gene summary
Fusion gene informationFusion gene name: BBX-KPNA4
Fusion gene ID: 9120
HgeneTgene
Gene symbol

BBX

KPNA4

Gene ID

56987

3840

Gene nameBBX high mobility group box domain containingkaryopherin subunit alpha 4
SynonymsARTC1|HBP2|HSPC339|MDS001IPOA3|QIP1|SRP3
Cytomap

3q13.12

3q25.33

Type of geneprotein-codingprotein-coding
DescriptionHMG box transcription factor BBXAg recognized by Treg cells 1BBX, HMG-box containingHMG box-containing protein 2bobby sox homologx 001 proteinimportin subunit alpha-3importin alpha Q1importin subunit alpha-4karyopherin alpha 4 (importin alpha 3)
Modification date2020031320200327
UniProtAcc

Q8WY36

O00629

Ensembl transtripts involved in fusion geneENST00000325805, ENST00000402543, 
ENST00000406780, ENST00000415149, 
ENST00000416476, ENST00000473542, 
ENST00000469804, ENST00000334256, 
Fusion gene scores* DoF score14 X 12 X 8=13445 X 4 X 4=80
# samples 175
** MAII scorelog2(17/1344*10)=-2.98292648664106
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/80*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BBX [Title/Abstract] AND KPNA4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBBX(107466886)-KPNA4(160227659), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across BBX (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across KPNA4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-D3-A2J8-06ABBXchr3

107466886

-KPNA4chr3

160227659

-
ChimerDB4SKCMTCGA-D3-A2J8-06ABBXchr3

107466886

+KPNA4chr3

160227659

-


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Fusion Gene ORF analysis for BBX-KPNA4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000325805ENST00000469804BBXchr3

107466886

+KPNA4chr3

160227659

-
5CDS-intronENST00000402543ENST00000469804BBXchr3

107466886

+KPNA4chr3

160227659

-
5CDS-intronENST00000406780ENST00000469804BBXchr3

107466886

+KPNA4chr3

160227659

-
5CDS-intronENST00000415149ENST00000469804BBXchr3

107466886

+KPNA4chr3

160227659

-
5CDS-intronENST00000416476ENST00000469804BBXchr3

107466886

+KPNA4chr3

160227659

-
In-frameENST00000325805ENST00000334256BBXchr3

107466886

+KPNA4chr3

160227659

-
In-frameENST00000402543ENST00000334256BBXchr3

107466886

+KPNA4chr3

160227659

-
In-frameENST00000406780ENST00000334256BBXchr3

107466886

+KPNA4chr3

160227659

-
In-frameENST00000415149ENST00000334256BBXchr3

107466886

+KPNA4chr3

160227659

-
In-frameENST00000416476ENST00000334256BBXchr3

107466886

+KPNA4chr3

160227659

-
intron-3CDSENST00000473542ENST00000334256BBXchr3

107466886

+KPNA4chr3

160227659

-
intron-intronENST00000473542ENST00000469804BBXchr3

107466886

+KPNA4chr3

160227659

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000415149BBXchr3107466886+ENST00000334256KPNA4chr3160227659-869011523151580421
ENST00000402543BBXchr3107466886+ENST00000334256KPNA4chr3160227659-878212444191672417
ENST00000325805BBXchr3107466886+ENST00000334256KPNA4chr3160227659-865011122751540421
ENST00000416476BBXchr3107466886+ENST00000334256KPNA4chr3160227659-858310452081473421
ENST00000406780BBXchr3107466886+ENST00000334256KPNA4chr3160227659-890013625371790417

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000415149ENST00000334256BBXchr3107466886+KPNA4chr3160227659-0.0001786560.99982136
ENST00000402543ENST00000334256BBXchr3107466886+KPNA4chr3160227659-0.000186770.99981326
ENST00000325805ENST00000334256BBXchr3107466886+KPNA4chr3160227659-0.0001810950.999819
ENST00000416476ENST00000334256BBXchr3107466886+KPNA4chr3160227659-0.0001768140.9998233
ENST00000406780ENST00000334256BBXchr3107466886+KPNA4chr3160227659-0.0001717180.9998282

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Fusion Genomic Features for BBX-KPNA4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for BBX-KPNA4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:107466886/chr3:160227659)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BBX

Q8WY36

KPNA4

O00629

FUNCTION: Transcription factor that is necessary for cell cycle progression from G1 to S phase. {ECO:0000269|PubMed:11680820}.FUNCTION: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBBXchr3:107466886chr3:160227659ENST00000325805+91841_50275942.0Compositional biasNote=Poly-Glu
HgeneBBXchr3:107466886chr3:160227659ENST00000406780+81641_50275912.0Compositional biasNote=Poly-Glu
HgeneBBXchr3:107466886chr3:160227659ENST00000415149+91741_50275912.0Compositional biasNote=Poly-Glu
HgeneBBXchr3:107466886chr3:160227659ENST00000325805+91880_148275942.0DNA bindingHMG box
HgeneBBXchr3:107466886chr3:160227659ENST00000406780+81680_148275912.0DNA bindingHMG box
HgeneBBXchr3:107466886chr3:160227659ENST00000415149+91780_148275912.0DNA bindingHMG box
TgeneKPNA4chr3:107466886chr3:160227659ENST000003342561217401_443379522.0RepeatNote=ARM 9
TgeneKPNA4chr3:107466886chr3:160227659ENST000003342561217447_485379522.0RepeatNote=ARM 10%3B atypical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBBXchr3:107466886chr3:160227659ENST00000325805+918326_370275942.0Coiled coilOntology_term=ECO:0000255
HgeneBBXchr3:107466886chr3:160227659ENST00000406780+816326_370275912.0Coiled coilOntology_term=ECO:0000255
HgeneBBXchr3:107466886chr3:160227659ENST00000415149+917326_370275912.0Coiled coilOntology_term=ECO:0000255
HgeneBBXchr3:107466886chr3:160227659ENST00000325805+918446_542275942.0Compositional biasNote=Lys-rich
HgeneBBXchr3:107466886chr3:160227659ENST00000325805+918671_773275942.0Compositional biasNote=Lys-rich
HgeneBBXchr3:107466886chr3:160227659ENST00000406780+816446_542275912.0Compositional biasNote=Lys-rich
HgeneBBXchr3:107466886chr3:160227659ENST00000406780+816671_773275912.0Compositional biasNote=Lys-rich
HgeneBBXchr3:107466886chr3:160227659ENST00000415149+917446_542275912.0Compositional biasNote=Lys-rich
HgeneBBXchr3:107466886chr3:160227659ENST00000415149+917671_773275912.0Compositional biasNote=Lys-rich
TgeneKPNA4chr3:107466886chr3:160227659ENST000003342561217233_236379522.0Compositional biasNote=Poly-Pro
TgeneKPNA4chr3:107466886chr3:160227659ENST0000033425612172_58379522.0DomainIBB
TgeneKPNA4chr3:107466886chr3:160227659ENST00000334256121743_52379522.0MotifNuclear localization signal
TgeneKPNA4chr3:107466886chr3:160227659ENST000003342561217137_229379522.0RegionNLS binding site (major)
TgeneKPNA4chr3:107466886chr3:160227659ENST000003342561217306_394379522.0RegionNLS binding site (minor)
TgeneKPNA4chr3:107466886chr3:160227659ENST000003342561217107_149379522.0RepeatNote=ARM 2
TgeneKPNA4chr3:107466886chr3:160227659ENST000003342561217150_194379522.0RepeatNote=ARM 3
TgeneKPNA4chr3:107466886chr3:160227659ENST000003342561217195_233379522.0RepeatNote=ARM 4
TgeneKPNA4chr3:107466886chr3:160227659ENST000003342561217234_278379522.0RepeatNote=ARM 5
TgeneKPNA4chr3:107466886chr3:160227659ENST000003342561217279_318379522.0RepeatNote=ARM 6
TgeneKPNA4chr3:107466886chr3:160227659ENST000003342561217319_360379522.0RepeatNote=ARM 7
TgeneKPNA4chr3:107466886chr3:160227659ENST000003342561217361_400379522.0RepeatNote=ARM 8
TgeneKPNA4chr3:107466886chr3:160227659ENST00000334256121766_106379522.0RepeatNote=ARM 1%3B truncated


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Fusion Gene Sequence for BBX-KPNA4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>9120_9120_1_BBX-KPNA4_BBX_chr3_107466886_ENST00000325805_KPNA4_chr3_160227659_ENST00000334256_length(transcript)=8650nt_BP=1112nt
ATGTGGAGCAGTGTACAGTGAAGCGGAGGCAGAGCGGCTCCGCGAGCTTCTCTCCACTTTCCCATAGAGAAACCCTGACTGGCCGCTGAG
GGCTAGCTACACACACGCCCTCACGCCCGGCGAGCCCGCGAGGTCACTATCATATGACAAAGGCTTTGCCGCAGTTCATCTTCCTCCCTG
TGTACTTTCCATTTGCCTTCCTGGAATCCTGCTGCATCACAGAAGCTGGAAGTTCTGATGTTCCACTGAAATCACAATGGAAAGTCTTGA
CTTGACTGGTCACAGTAATGAAAGGCAGTAATAGAAATAAGGATCATTCAGCAGAAGGAGAAGGGGTTGGAAAACGACCAAAACGAAAGT
GTCTTCAGTGGCATCCATTGCTAGCAAAGAAACTTCTTGATTTTTCAGAAGAGGAAGAAGAGGAAGACGAAGAGGAGGATATTGATAAGG
TTCAACTTCTTGGGGCCGATGGCCTAGAGCAAGATGTTGGTGAAACTGAAGATGATGAATCACCAGAGCAGCGAGCCCGGAGACCAATGA
ATGCATTTCTTTTATTTTGCAAACGCCATCGCTCTCTTGTACGTCAGGAACACCCCAGGCTTGATAACCGAGGTGCTACCAAGATACTAG
CTGATTGGTGGGCTGTTCTTGATCCAAAGGAAAAGCAGAAATACACAGACATGGCCAAGGAGTATAAGGATGCATTTATGAAAGCAAATC
CTGGCTACAAATGGTGTCCTACCACAAACAAGCCTGTGAAATCCCCAACACCCACTGTCAATCCACGAAAGAAACTTTGGGCCTTCCCAT
CTGACTCTTCAAGAGACTTGCCAAGCCCCAAGAAAGCAAAGACTGAAGAAATGCCTCAGCTTAACTTTGGAATGGCTGATCCTACTCAAA
TGGGAGGCCTGAGTATGCTGCTGTTAGCTGGAGAACATGCTCTTGGCACACCAGAGGTATCCTCTGGCACATGCAGGCCTGATGTTTCAG
AATCTCCTGAATTACGTCAGAAGTCACCATTGTTTCAGTTTGCCGAGATATCTTCAAGTACGTCCCACTCTGATGCTTCTACAAAGCAGT
GTCAAACATCTGCCTTGTTTCAGTTTGCAGAGGGGGATTTTGGCACTCAAAAAGAAGCTGCTTGGGCCATAAGTAACTTAACAATTAGTG
GAAGGAAAGATCAAGTGGCTTACCTTATCCAACAAAATGTTATCCCACCTTTTTGCAACTTGCTGACTGTAAAAGATGCACAAGTTGTGC
AAGTAGTACTCGATGGACTAAGTAATATATTAAAAATGGCTGAAGATGAGGCAGAAACCATAGGCAATCTTATAGAAGAATGTGGAGGGC
TGGAGAAAATTGAACAACTTCAAAATCATGAAAATGAAGACATCTACAAATTGGCCTATGAGATCATTGATCAGTTCTTCTCTTCAGATG
ATATTGATGAAGACCCTAGCCTTGTTCCAGAGGCAATTCAAGGCGGAACATTTGGTTTCAATTCATCTGCCAATGTACCAACAGAAGGGT
TCCAGTTTTAGAAAGATGTTGTGGAAGTTAGGTACAATGCAGCACTGAGATATATATATATATATGTGTGTGTGTATATATATATATATA
TACATATATATAAAAAGGTTTGATCCATCAAGCTTGGCTCATGGGATCTGCTGCTGCATTAAATCGGGAAAGAAAATGTGAAGATTTCAT
TTGGAATCACAGAAAATGCCCAAATGAGGTCAAGATGGCGAGTGGGTGCGAGTGAGAATGAGTGGCAAAATGTAATGAAAACTTTACATG
AATGCTTATTTAGGTTGTTCAAAGTAAAAAGGGCTACAGGTCACAGATCGTCAGTGCCTGAGAAAGAACATTGACTTACTCTATATCAAT
TGAGGGGAAAGTGCAGTACCGTCATCTTCAAGCCTTGTAAGCATAAAAGAGAATAGGCTGCCCATATAAGTCAAAGGAAAATGAGCCCAG
GCCTTGCTATGAAGCAGTGTGTGAATGGACAATGTTGAATGAATGTCTGGCTCAGTGATGGAGAGCCAGGTTCATCTTTGAAATCTAGGG
CTCTTCACTCATGAAGCAGACTCCTAGTCCTGGAGTGACTGTGTACGAGAGCGTGGTTGTGGTGCTGTATGTGAACGCATGCAAGCTTGA
TTCACCTTCAGGGGGCTGATAACCTAGTAAATCATCAAAATGAGATCATAAGTGTTAATGTACACTGGACATGAAAACAAAGACTGGTTT
AGCAGCAGACATTGGTTTACTCTGCAGCCTGTGTTTTCTGTTTCCCCCTTTCCCACCTCCTTCCCCCCACCCAATCCTTTTTTTTTTCTT
TTTTGCTTTTCTTTTCTTTTTTTTTAGTTTTTATTTACTTTACCTAGTATGCCTTTTTTTAGTTGCTTCTCAAGTCAGAAAACTTTTCAG
GAAGGTTTCCCTGTGCATTTGCACCAGATGAATGTTTGATGCTATGAAAAGCTTTCCATATCATCAAAACTAATTTGTGTAGATTTTTGC
ATGAAAAAAATCATAAATTTCCCTCAAAATAGACTGTGTTGCAGTACACAAGTTGCCATAATAGTATAAAACAGTAAAATGTGCTTAAAA
GGCCATCCTTTTCATTTTCAGAGATAACATAAAGATCTTTGCATGAGGTAAATCTACAGCATAGTTCATTTTTAGATTTTGTTGAGTCCT
GTAAAGAAGAAGAAGAAAAAAGTTTCAGTTGTGGTAGAATACCGTGCTGTGTTTAAATGTTACTTGTTTTCAAACTTTGTTTTCTATGAA
AATGATATGGAAACTTCTAAAATGGAATTTGGTGCATATGTACTGCTGAATAAAGACCGATGAAGAGGTTTGAGTAGATGTACAAATCAA
GTAATGGTTTGAACACCTTTAATAATATGCCTAATCTGTTCAATTGTTTTAGAATCTTTTTATCTTAGATGTAGGCAGCCATGAACAATC
TATTTTGAGCCACTTTAGGGAGAAAACTTTGTATTTTTAAAACTTGCATAAAAGTTATGCAAGTGGTTTTTATAAATTGGAATAATACCT
CAGTTTTGAGGTTATGCACACTAAATTAAATGTGACATAAATTAATTTGTACAAAAAGAACTCTTTATAAGGTGGCTCATTGTAGGAAAT
CCTGTGCCTTCCCCTTTGAGCACAAGTGTTGCATGAACAACAGTTTGCTATAAGAAACATACCAGATTAGCCACCATTAGCATCTATATC
TACTTTGTGTTTAAAAATCAACTGGTAATTCTGAAACACTGTAGAATGGATAAAAATTATTTTGTGATCATAACTCTTTGTTGAACTAGA
GTATTTTTGCAGCATTCCTTGTCATCAGAAACATGGTTAAAGTTTAAAACTAGAAGCAGCAGAAAACTAGCTTGTAAAATTTATCCAAGT
AGAGTGCAGGCTAGGCTGTCTTGGGGAAATAAACATTAAAACTTAAAGCAATGTTTTACATGGGGTGTGTGTGTGTGGTGTGTGGATTTT
TTTTTTTTTATAAAGTTAGAGTATAATTCAATGGCTTACATTAGCTTCCTGTCTTTTTACCTAGAACCAGCATAATAAGAAATTTCTTTG
GTTCTGTCATTTCAGTATGGACATATTAATATTTTAGCCCACTGAGTTTGTCCAGTTGACACCATCAGTGCTTCAGTTTTCTCTCTATCC
AAAGCAAGGTTTTAACTTTCCTTCATTCTCCAGTAAAACAGACCGAGACAACTTGAACTATATTTTGAGTATTGCTATATCTTCAACATA
TAGCTCCAAATGATGGATTGTATACAAAGCATAGTACAGAAGGTTTCAGTAATTGGAAGGTGAACACAGCAATGCTTTACATAATTTGTG
TTTTTTAGTAAAAAATATTGGATTCAAAGTAAGCCAATGAGCTTGTATACAAATTTTATATACAAATTATTGTATAGAACAGTGATATGG
AAAATAGGTAAGGGTGATATTAATATCTCTGGGTATAAGGACTACCTTATCGTTTAAATATTTTATTTCCATCTATAGCCTAATATAGAA
CATTGATTTTCTAGTAGAAATTCTGGGAAGGGCTTTTCTGTCTCTGAAATTGATTCAGTACAGTTGACAGTTCATCACGGTTACCTGGTT
AAACACTTTTTTTTTTTTTTTAATTCTCCAGTGATCTAGGAAATTGTTTCATTTTTAACACAGGCTTATTTCTGATGGGGATGGGGGCAT
AGAATAATATGCCTAATAAGCTAAACGTTCTTAACGTTTCATGTCTTAAACTGTCTTTTTGAACATTGAGACCACCTCAAGTGCTGTAAA
AATAAGAATGTTATATTAGGGGTGTGTGAGACGCCCTAGTCTAAAATCTATCTTTAAATATATTTCCTTTGTAATTTTCAAAGACTTCAG
TAATTGTGTGTTATGGTGGAAATAATACTTTCCATTGGTCCACATTGCTCTGGACCAAACCTGGAGCATTTCTATAATTAGAGCTATCTA
TGAATCATTAAAAATGGATCTAGAATAATTTTGGGGAGAGGGAGTGTATCATTTAGTTTAGGCTTACCTCAGCAGCACTTCATAGGGTGA
GGAGTTGTTTGTTTCTTTAAAGGTATAACTGCATTGTAAAATGACTGGGTTTATTGTAACAGTAATTTATGGGGGCACCCTTTTTGGATT
CTCCATTGCCTCAGTTTCCTCAAGGAAAAAGTTACAGAGATTAAGCTAAATTTTGAATTTAGAGAATAACTGCTGTGTAATTTTGGTATA
ATTACCATAAATTTAGTGTCTTAAAACACAACATACATTATTTCACAATTTCTGTAGGTCAAGAGTGTAGTTAGGTTTTCTGCTCAGGGT
CTCACAAGGCTGCAATAAAGGTGTCAGCCAGAGCTGCAGTCTTATCTGAAGCTAGGGGGTCCTCTTTTATGCACATATGGCAAAATCCAT
TGCCTAGCAACTGAAGAAATCATGGGAACTTCTTCAAGGCCAGCAAGAGAATCTCTGATCTCAGGGAAGGCCTTAAGCGCTTTTTTAAAG
GTCTCACCTGATTAGATCAGGCCACCTACCCACCAGGGTGATCTCCCTTTTGATTAACCCAAAGCCAAACTGATGAGGTACCTTCATTAC
CCCTGCAAAATCCCTTCACCTTTGCCCTGCATTGTAGTCCAATCACAGGGGTGATACGCATCATATTCAAAGATCCTGTTCACAGTCAAG
GGAGGGGGTTATATGGAGTATGTATACCAGGGAATCTTGGGAGCCATCTTAAGAGTTCTTCCTATGACAAGGACTCAACTATTTAGAACT
GGAACAATTTACAAGTGATAGCCTTATATAGTTATCATAGCAAGCTTATTTGGGGATCAAGGTTGCCTCTGAGAACCTAATGAAAACTGG
ACCAGCTTCCCCAAAAAGTGTATATACATGGTAGTTTTTCATACAGTTTTAGGGGATTCATAAGAGTCCATGAATTACAGTCTGTCCCAA
CCCTTCCCTTTAGATGATGAGTTGTTGAGGTGACTTGCCCAAGGTCACACAGCTACTAAGGGCCAAATAAAGCCCACATCTCAACTCCCA
TACTGCCCAGGGCTTCTAATTACTATTCTAAAGGTAATCTAAATTCATTTAAATTTGTGAACCAATGCAAAAAAATGTGAATGTAGCTTT
TTGGATATTTTTTTTGTTTACTAAGGAATGGGTAACATTGTTATAGAAGCTTGCCTAAGAGTTTTGAAATTAGTTGACCTTTTTGAGTTT
CCAAAATTGAATCTTCCATTGTAGCTATTAAAGTGAACTATAAATAGGCCAACTTTAATTGTTAACTCCTCGGGTTTGGTGGATTATCTA
CCATTTATATATAAAATTTCAGTTAGAATCCACCATTGGCGTTTTGAAGGCCAAGATAGCTGAGTATCTTATCCTTTTTGTAACTTCTTG
ATTATTTTACTTATTGGCAAAATTCATTAACTGTCAGCCAATAATTTAATATTATGGGAGGAAAAAATTTTGCCCAGATATCTGAGGCAA
TACTCCCAAACACTAACAAACTGATGCCTAACAAACTTGACATTTTGAACACTTAAAGTTTTCCCTAAACTTTTTAATAAGCACATTAAT
AAAGTATGCTTTTAAATATATATGTACAATAATTTTTAAAAGTTGCTGCAAGATGCCTTCAAATCAATATGCACGTTGGTGGCATTAGTG
CAGTCTTCTATTTTTATTTTTTTGAGACACAGTCTCGCTCTGTGGCCCAGGCTGGAGTGTAGTGGCGCAATCTCGGCTCACTGCAACCTC
TGCCTCAAGGGTTCAAGCAATTCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGAGTACGCTACCACGCCTGGCTAATTTTTGTATTT
TTAGTAGAAATGGGGTTTCACCGTATTGGCCAGGCTGGTATTGGAATCCTGACCGCAAATGATCTGCCCACCTCGGCTTCCCAAAGTGCT
GGGATTACAGGCGTGAGCCACTGCGCCCAACCAGCCTTAATTCTTAATAAAGGAAGTTGAAAAATAATGAACATTGGTAAAACTATTCTA
GTGTGATCAGAAGCAAATTTGGACTGTAGTGTCAAATTGATAAAAAACTAAGCACACCAATCATGTATAAGAAAAGTAGATTTAACATTT
TTTTCCCTAAACACTTAACCCAGAAGTTAACAATAATCTTGAAAATTCCTTTTAAATCCAGGCCCTTTAGGTGATGGCAGTTTGACTCAG
GATGTCCAAGTCCAGTGTATTTTCAATAAAATTGACTTGACAGCTACTGCTCTGGGTGTAAGAGCAGTTGACTGTGAGGAAAAGTAAATG
GTTCTACAGATTCTTTATGATCTACCTCCCACCAGAGGACTGCAGTACTCCCTTGTTATTTATATTTTCTGCCCCAATTTTTGCCTTCTC
CACAAATTTTATACCTTTTGTAGCTGCCTACTCCAGATTACTTCACCTTTCCAGACTATCAGTTCTTCCACTTTTATTCTTCATAAAGAA
AATTCCAATAACCTGTTTCACTTAGGTTTTTCTATTACTCTTCAAGCATGAATCCTAATTTCCCTGACTATATCTTACCTCTGATCTCCA
TAACTGATGGATTCCTATCCTAGACTATGTTACTCTAATATTACCCAAGATTTTCTCCAGCCTGTTTTTACTCTTACTTTGAAACAGCTG
TTTAAAATGACTCGTAATCTGCTTAAATCTACATGCTTTTTGTGGTTCTCAATCCAGTTACCTACCTTCCAGATAATTCCCTCACTGTCC
TGTCCTCTCCATTCCTCTGATGTTTAAGCCCTGTGAGCCACCTTTCCCCCATCCTTTGTGCATAGTTACCATTTTACTCTTTCTTGTTGC
CCAGGCAGGAATGCAGTGGTGCCATCTTGGCTCACTGCAACCTCCACCTCCTAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAG
CTGGGACCACAAGCGTGCACCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCACGTTGGCCAGGCTGGTCTCG
AACTCCTGACCTCAGATGATCCACCCTCCTTGGCCTCCCAAAGTGCTGGGATTGCAGGCGTGAGCCACCGCCTGGCCACCATTTTACTCT
TTTTAGGTACAGTAATCTAATATCCAAAGTCTTGGACTCAGCTAAAGAGGGTATTTACCTTAAAAAAAAAAAAAAAAAGACTCCATCTTT
TGATTCATAATTGTGGTGGGGGCGGGGAATCAAGACAACCTTAGTCACTTTGGTATTACCATAATTCTTGTCTTTTCAGGGTTGTCCTGT
TCAGCTGCATAAAACATCATGTATTCTAGGTATTTCCTACCTTCACTTACATTTTTACTTGCCGATGTGCTGCCTTCATAAATGGGTATA
TTCCGCCACACATCTAGTAAGCCCCCAATGCAGTACACAATGTGTATCACTGATAAAACTCGCACTTCTGCCATGTCAGTATTATATTCA
GTTGAGTGGTCTTTAGCATAGTGGCAGTCCTAGTCATCCTAACCTTTTAGTTAAGGTAAAATTACATATGTTTATAGAACTCATATAGAC
AAGCTAGTTTTTAAAATCTTCCTTTTAACCAGTTTAGGATGATCTAGGATAGCTAAGTTACCTACATGGTGACTGTTCGGTCTAATTCAG
AAACAGAAGTACTAAAAGAATACTAAAAAGTTTTTACCCATTATCTCTATCCCTGTTTTCTTTTTGCAATTCTCAGCTGCAGGGAGCAAG
AAAATACACAGCAGATAGGAAATGTTTGTTTGCATCCTGGCTTTCTCAACCGCACTTTACGTCCTTGAATATTCTAGATATTTACTCCTT
CAAGAAGTCAGGAGTATATCCAGGCCTACCTATCATCCTTGCCATCCCCATTAACCCTCATTTTTCAGTATGTGTTTTACATTTATGGTT
ATTTTTCAGTCTATAGTATCTGTTCACTCATTGCTCTATCACATCTGAGTTTCTCCGTCTTTCTTTCCACTAGATTGTAAGCTCCTTAAG
GGCAAGGTCGGCATATAAGCAAAGTTCTGTAAACACCGTGAAGGTACCATGAGTTCTATGGGTACTCAATAAATGCTTGTGATAATGATG

>9120_9120_1_BBX-KPNA4_BBX_chr3_107466886_ENST00000325805_KPNA4_chr3_160227659_ENST00000334256_length(amino acids)=421AA_BP=274
MVTVMKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRARRPMNA
FLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSD
SSRDLPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELRQKSPLFQFAEISSSTSHSDASTKQCQ
TSALFQFAEGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLE

--------------------------------------------------------------
>9120_9120_2_BBX-KPNA4_BBX_chr3_107466886_ENST00000402543_KPNA4_chr3_160227659_ENST00000334256_length(transcript)=8782nt_BP=1244nt
GGTTGCATGTACTGTATGTGGAGCAGTGTACAGTGAAGCGGAGGCAGAGCGGCTCCGCGAGCTTCTCTCCACTTTCCCATAGAGAAACCC
TGACTGGCCGCTGAGGGCTAGCTACACACACGCCCTCACGCCCGGCGAGCCCGCGAGGTCACTATCATATGACAAAGGCTTTGCCGCAGT
TCATCTTCCTCCCTGTGTACTTTCCATTTGCCTTCCTGGAATCCTGCTGCATCACAGAAGCTGGAAGTTCTGATGTTCCACTGAAATCAC
AATGGAAAGTCTTGACTTGACTGGCACCCTCAGGAAGACCCCAAGCCTCTAGCAGTACCTGGTATCATCTCCAGCATGTTATAGATGTGG
AGGATTCACTGGGATATTGAGAAATACCAGAGGCGAATTGTTCCACTGTAGTCACAGTAATGAAAGGCAGTAATAGAAATAAGGATCATT
CAGCAGAAGGAGAAGGGGTTGGAAAACGACCAAAACGAAAGTGTCTTCAGTGGCATCCATTGCTAGCAAAGAAACTTCTTGATTTTTCAG
AAGAGGAAGAAGAGGAAGACGAAGAGGAGGATATTGATAAGGTTCAACTTCTTGGGGCCGATGGCCTAGAGCAAGATGTTGGTGAAACTG
AAGATGATGAATCACCAGAGCAGCGAGCCCGGAGACCAATGAATGCATTTCTTTTATTTTGCAAACGCCATCGCTCTCTTGTACGTCAGG
AACACCCCAGGCTTGATAACCGAGGTGCTACCAAGATACTAGCTGATTGGTGGGCTGTTCTTGATCCAAAGGAAAAGCAGAAATACACAG
ACATGGCCAAGGAGTATAAGGATGCATTTATGAAAGCAAATCCTGGCTACAAATGGTGTCCTACCACAAACAAGCCTGTGAAATCCCCAA
CACCCACTGTCAATCCACGAAAGAAACTTTGGGCCTTCCCATCTGACTCTTCAAGAGACTTGCCAAGCCCCAAGAAAGCAAAGACTGAAG
AAATGCCTCAGCTTAACTTTGGAATGGCTGATCCTACTCAAATGGGAGGCCTGAGTATGCTGCTGTTAGCTGGAGAACATGCTCTTGGCA
CACCAGAGGTATCCTCTGGCACATGCAGGCCTGATGTTTCAGAATCTCCTGAATTACGTCAGAAGTCACCATTGTTTCAGTTTGCCGAGA
TATCTTCAAGTACGTCCCACTCTGATGCTTCTACAAAGCAGTGTCAAACATCTGCCTTGTTTCAGTTTGCAGAGGGGGATTTTGGCACTC
AAAAAGAAGCTGCTTGGGCCATAAGTAACTTAACAATTAGTGGAAGGAAAGATCAAGTGGCTTACCTTATCCAACAAAATGTTATCCCAC
CTTTTTGCAACTTGCTGACTGTAAAAGATGCACAAGTTGTGCAAGTAGTACTCGATGGACTAAGTAATATATTAAAAATGGCTGAAGATG
AGGCAGAAACCATAGGCAATCTTATAGAAGAATGTGGAGGGCTGGAGAAAATTGAACAACTTCAAAATCATGAAAATGAAGACATCTACA
AATTGGCCTATGAGATCATTGATCAGTTCTTCTCTTCAGATGATATTGATGAAGACCCTAGCCTTGTTCCAGAGGCAATTCAAGGCGGAA
CATTTGGTTTCAATTCATCTGCCAATGTACCAACAGAAGGGTTCCAGTTTTAGAAAGATGTTGTGGAAGTTAGGTACAATGCAGCACTGA
GATATATATATATATATGTGTGTGTGTATATATATATATATATACATATATATAAAAAGGTTTGATCCATCAAGCTTGGCTCATGGGATC
TGCTGCTGCATTAAATCGGGAAAGAAAATGTGAAGATTTCATTTGGAATCACAGAAAATGCCCAAATGAGGTCAAGATGGCGAGTGGGTG
CGAGTGAGAATGAGTGGCAAAATGTAATGAAAACTTTACATGAATGCTTATTTAGGTTGTTCAAAGTAAAAAGGGCTACAGGTCACAGAT
CGTCAGTGCCTGAGAAAGAACATTGACTTACTCTATATCAATTGAGGGGAAAGTGCAGTACCGTCATCTTCAAGCCTTGTAAGCATAAAA
GAGAATAGGCTGCCCATATAAGTCAAAGGAAAATGAGCCCAGGCCTTGCTATGAAGCAGTGTGTGAATGGACAATGTTGAATGAATGTCT
GGCTCAGTGATGGAGAGCCAGGTTCATCTTTGAAATCTAGGGCTCTTCACTCATGAAGCAGACTCCTAGTCCTGGAGTGACTGTGTACGA
GAGCGTGGTTGTGGTGCTGTATGTGAACGCATGCAAGCTTGATTCACCTTCAGGGGGCTGATAACCTAGTAAATCATCAAAATGAGATCA
TAAGTGTTAATGTACACTGGACATGAAAACAAAGACTGGTTTAGCAGCAGACATTGGTTTACTCTGCAGCCTGTGTTTTCTGTTTCCCCC
TTTCCCACCTCCTTCCCCCCACCCAATCCTTTTTTTTTTCTTTTTTGCTTTTCTTTTCTTTTTTTTTAGTTTTTATTTACTTTACCTAGT
ATGCCTTTTTTTAGTTGCTTCTCAAGTCAGAAAACTTTTCAGGAAGGTTTCCCTGTGCATTTGCACCAGATGAATGTTTGATGCTATGAA
AAGCTTTCCATATCATCAAAACTAATTTGTGTAGATTTTTGCATGAAAAAAATCATAAATTTCCCTCAAAATAGACTGTGTTGCAGTACA
CAAGTTGCCATAATAGTATAAAACAGTAAAATGTGCTTAAAAGGCCATCCTTTTCATTTTCAGAGATAACATAAAGATCTTTGCATGAGG
TAAATCTACAGCATAGTTCATTTTTAGATTTTGTTGAGTCCTGTAAAGAAGAAGAAGAAAAAAGTTTCAGTTGTGGTAGAATACCGTGCT
GTGTTTAAATGTTACTTGTTTTCAAACTTTGTTTTCTATGAAAATGATATGGAAACTTCTAAAATGGAATTTGGTGCATATGTACTGCTG
AATAAAGACCGATGAAGAGGTTTGAGTAGATGTACAAATCAAGTAATGGTTTGAACACCTTTAATAATATGCCTAATCTGTTCAATTGTT
TTAGAATCTTTTTATCTTAGATGTAGGCAGCCATGAACAATCTATTTTGAGCCACTTTAGGGAGAAAACTTTGTATTTTTAAAACTTGCA
TAAAAGTTATGCAAGTGGTTTTTATAAATTGGAATAATACCTCAGTTTTGAGGTTATGCACACTAAATTAAATGTGACATAAATTAATTT
GTACAAAAAGAACTCTTTATAAGGTGGCTCATTGTAGGAAATCCTGTGCCTTCCCCTTTGAGCACAAGTGTTGCATGAACAACAGTTTGC
TATAAGAAACATACCAGATTAGCCACCATTAGCATCTATATCTACTTTGTGTTTAAAAATCAACTGGTAATTCTGAAACACTGTAGAATG
GATAAAAATTATTTTGTGATCATAACTCTTTGTTGAACTAGAGTATTTTTGCAGCATTCCTTGTCATCAGAAACATGGTTAAAGTTTAAA
ACTAGAAGCAGCAGAAAACTAGCTTGTAAAATTTATCCAAGTAGAGTGCAGGCTAGGCTGTCTTGGGGAAATAAACATTAAAACTTAAAG
CAATGTTTTACATGGGGTGTGTGTGTGTGGTGTGTGGATTTTTTTTTTTTTATAAAGTTAGAGTATAATTCAATGGCTTACATTAGCTTC
CTGTCTTTTTACCTAGAACCAGCATAATAAGAAATTTCTTTGGTTCTGTCATTTCAGTATGGACATATTAATATTTTAGCCCACTGAGTT
TGTCCAGTTGACACCATCAGTGCTTCAGTTTTCTCTCTATCCAAAGCAAGGTTTTAACTTTCCTTCATTCTCCAGTAAAACAGACCGAGA
CAACTTGAACTATATTTTGAGTATTGCTATATCTTCAACATATAGCTCCAAATGATGGATTGTATACAAAGCATAGTACAGAAGGTTTCA
GTAATTGGAAGGTGAACACAGCAATGCTTTACATAATTTGTGTTTTTTAGTAAAAAATATTGGATTCAAAGTAAGCCAATGAGCTTGTAT
ACAAATTTTATATACAAATTATTGTATAGAACAGTGATATGGAAAATAGGTAAGGGTGATATTAATATCTCTGGGTATAAGGACTACCTT
ATCGTTTAAATATTTTATTTCCATCTATAGCCTAATATAGAACATTGATTTTCTAGTAGAAATTCTGGGAAGGGCTTTTCTGTCTCTGAA
ATTGATTCAGTACAGTTGACAGTTCATCACGGTTACCTGGTTAAACACTTTTTTTTTTTTTTTAATTCTCCAGTGATCTAGGAAATTGTT
TCATTTTTAACACAGGCTTATTTCTGATGGGGATGGGGGCATAGAATAATATGCCTAATAAGCTAAACGTTCTTAACGTTTCATGTCTTA
AACTGTCTTTTTGAACATTGAGACCACCTCAAGTGCTGTAAAAATAAGAATGTTATATTAGGGGTGTGTGAGACGCCCTAGTCTAAAATC
TATCTTTAAATATATTTCCTTTGTAATTTTCAAAGACTTCAGTAATTGTGTGTTATGGTGGAAATAATACTTTCCATTGGTCCACATTGC
TCTGGACCAAACCTGGAGCATTTCTATAATTAGAGCTATCTATGAATCATTAAAAATGGATCTAGAATAATTTTGGGGAGAGGGAGTGTA
TCATTTAGTTTAGGCTTACCTCAGCAGCACTTCATAGGGTGAGGAGTTGTTTGTTTCTTTAAAGGTATAACTGCATTGTAAAATGACTGG
GTTTATTGTAACAGTAATTTATGGGGGCACCCTTTTTGGATTCTCCATTGCCTCAGTTTCCTCAAGGAAAAAGTTACAGAGATTAAGCTA
AATTTTGAATTTAGAGAATAACTGCTGTGTAATTTTGGTATAATTACCATAAATTTAGTGTCTTAAAACACAACATACATTATTTCACAA
TTTCTGTAGGTCAAGAGTGTAGTTAGGTTTTCTGCTCAGGGTCTCACAAGGCTGCAATAAAGGTGTCAGCCAGAGCTGCAGTCTTATCTG
AAGCTAGGGGGTCCTCTTTTATGCACATATGGCAAAATCCATTGCCTAGCAACTGAAGAAATCATGGGAACTTCTTCAAGGCCAGCAAGA
GAATCTCTGATCTCAGGGAAGGCCTTAAGCGCTTTTTTAAAGGTCTCACCTGATTAGATCAGGCCACCTACCCACCAGGGTGATCTCCCT
TTTGATTAACCCAAAGCCAAACTGATGAGGTACCTTCATTACCCCTGCAAAATCCCTTCACCTTTGCCCTGCATTGTAGTCCAATCACAG
GGGTGATACGCATCATATTCAAAGATCCTGTTCACAGTCAAGGGAGGGGGTTATATGGAGTATGTATACCAGGGAATCTTGGGAGCCATC
TTAAGAGTTCTTCCTATGACAAGGACTCAACTATTTAGAACTGGAACAATTTACAAGTGATAGCCTTATATAGTTATCATAGCAAGCTTA
TTTGGGGATCAAGGTTGCCTCTGAGAACCTAATGAAAACTGGACCAGCTTCCCCAAAAAGTGTATATACATGGTAGTTTTTCATACAGTT
TTAGGGGATTCATAAGAGTCCATGAATTACAGTCTGTCCCAACCCTTCCCTTTAGATGATGAGTTGTTGAGGTGACTTGCCCAAGGTCAC
ACAGCTACTAAGGGCCAAATAAAGCCCACATCTCAACTCCCATACTGCCCAGGGCTTCTAATTACTATTCTAAAGGTAATCTAAATTCAT
TTAAATTTGTGAACCAATGCAAAAAAATGTGAATGTAGCTTTTTGGATATTTTTTTTGTTTACTAAGGAATGGGTAACATTGTTATAGAA
GCTTGCCTAAGAGTTTTGAAATTAGTTGACCTTTTTGAGTTTCCAAAATTGAATCTTCCATTGTAGCTATTAAAGTGAACTATAAATAGG
CCAACTTTAATTGTTAACTCCTCGGGTTTGGTGGATTATCTACCATTTATATATAAAATTTCAGTTAGAATCCACCATTGGCGTTTTGAA
GGCCAAGATAGCTGAGTATCTTATCCTTTTTGTAACTTCTTGATTATTTTACTTATTGGCAAAATTCATTAACTGTCAGCCAATAATTTA
ATATTATGGGAGGAAAAAATTTTGCCCAGATATCTGAGGCAATACTCCCAAACACTAACAAACTGATGCCTAACAAACTTGACATTTTGA
ACACTTAAAGTTTTCCCTAAACTTTTTAATAAGCACATTAATAAAGTATGCTTTTAAATATATATGTACAATAATTTTTAAAAGTTGCTG
CAAGATGCCTTCAAATCAATATGCACGTTGGTGGCATTAGTGCAGTCTTCTATTTTTATTTTTTTGAGACACAGTCTCGCTCTGTGGCCC
AGGCTGGAGTGTAGTGGCGCAATCTCGGCTCACTGCAACCTCTGCCTCAAGGGTTCAAGCAATTCTGCCTCAGCCTCCTGAGTAGCTGGG
ATTACAGGAGTACGCTACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAAATGGGGTTTCACCGTATTGGCCAGGCTGGTATTGGAATC
CTGACCGCAAATGATCTGCCCACCTCGGCTTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCAACCAGCCTTAATTCTTAAT
AAAGGAAGTTGAAAAATAATGAACATTGGTAAAACTATTCTAGTGTGATCAGAAGCAAATTTGGACTGTAGTGTCAAATTGATAAAAAAC
TAAGCACACCAATCATGTATAAGAAAAGTAGATTTAACATTTTTTTCCCTAAACACTTAACCCAGAAGTTAACAATAATCTTGAAAATTC
CTTTTAAATCCAGGCCCTTTAGGTGATGGCAGTTTGACTCAGGATGTCCAAGTCCAGTGTATTTTCAATAAAATTGACTTGACAGCTACT
GCTCTGGGTGTAAGAGCAGTTGACTGTGAGGAAAAGTAAATGGTTCTACAGATTCTTTATGATCTACCTCCCACCAGAGGACTGCAGTAC
TCCCTTGTTATTTATATTTTCTGCCCCAATTTTTGCCTTCTCCACAAATTTTATACCTTTTGTAGCTGCCTACTCCAGATTACTTCACCT
TTCCAGACTATCAGTTCTTCCACTTTTATTCTTCATAAAGAAAATTCCAATAACCTGTTTCACTTAGGTTTTTCTATTACTCTTCAAGCA
TGAATCCTAATTTCCCTGACTATATCTTACCTCTGATCTCCATAACTGATGGATTCCTATCCTAGACTATGTTACTCTAATATTACCCAA
GATTTTCTCCAGCCTGTTTTTACTCTTACTTTGAAACAGCTGTTTAAAATGACTCGTAATCTGCTTAAATCTACATGCTTTTTGTGGTTC
TCAATCCAGTTACCTACCTTCCAGATAATTCCCTCACTGTCCTGTCCTCTCCATTCCTCTGATGTTTAAGCCCTGTGAGCCACCTTTCCC
CCATCCTTTGTGCATAGTTACCATTTTACTCTTTCTTGTTGCCCAGGCAGGAATGCAGTGGTGCCATCTTGGCTCACTGCAACCTCCACC
TCCTAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACCACAAGCGTGCACCACCACGCCCGGCTAATTTTTGTATTTT
TAGTAGAGATGGGGTTTCACCACGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGATGATCCACCCTCCTTGGCCTCCCAAAGTGCTG
GGATTGCAGGCGTGAGCCACCGCCTGGCCACCATTTTACTCTTTTTAGGTACAGTAATCTAATATCCAAAGTCTTGGACTCAGCTAAAGA
GGGTATTTACCTTAAAAAAAAAAAAAAAAAGACTCCATCTTTTGATTCATAATTGTGGTGGGGGCGGGGAATCAAGACAACCTTAGTCAC
TTTGGTATTACCATAATTCTTGTCTTTTCAGGGTTGTCCTGTTCAGCTGCATAAAACATCATGTATTCTAGGTATTTCCTACCTTCACTT
ACATTTTTACTTGCCGATGTGCTGCCTTCATAAATGGGTATATTCCGCCACACATCTAGTAAGCCCCCAATGCAGTACACAATGTGTATC
ACTGATAAAACTCGCACTTCTGCCATGTCAGTATTATATTCAGTTGAGTGGTCTTTAGCATAGTGGCAGTCCTAGTCATCCTAACCTTTT
AGTTAAGGTAAAATTACATATGTTTATAGAACTCATATAGACAAGCTAGTTTTTAAAATCTTCCTTTTAACCAGTTTAGGATGATCTAGG
ATAGCTAAGTTACCTACATGGTGACTGTTCGGTCTAATTCAGAAACAGAAGTACTAAAAGAATACTAAAAAGTTTTTACCCATTATCTCT
ATCCCTGTTTTCTTTTTGCAATTCTCAGCTGCAGGGAGCAAGAAAATACACAGCAGATAGGAAATGTTTGTTTGCATCCTGGCTTTCTCA
ACCGCACTTTACGTCCTTGAATATTCTAGATATTTACTCCTTCAAGAAGTCAGGAGTATATCCAGGCCTACCTATCATCCTTGCCATCCC
CATTAACCCTCATTTTTCAGTATGTGTTTTACATTTATGGTTATTTTTCAGTCTATAGTATCTGTTCACTCATTGCTCTATCACATCTGA
GTTTCTCCGTCTTTCTTTCCACTAGATTGTAAGCTCCTTAAGGGCAAGGTCGGCATATAAGCAAAGTTCTGTAAACACCGTGAAGGTACC

>9120_9120_2_BBX-KPNA4_BBX_chr3_107466886_ENST00000402543_KPNA4_chr3_160227659_ENST00000334256_length(amino acids)=417AA_BP=270
MKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRARRPMNAFLLF
CKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSDSSRD
LPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELRQKSPLFQFAEISSSTSHSDASTKQCQTSAL
FQFAEGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQ

--------------------------------------------------------------
>9120_9120_3_BBX-KPNA4_BBX_chr3_107466886_ENST00000406780_KPNA4_chr3_160227659_ENST00000334256_length(transcript)=8900nt_BP=1362nt
TGCTCAGATCAGCTTCCTGCTTCTCATGAAAGCTGTTCCCCTATAAAGCTGGTCTGCTTTCACTGAAAGAATTATATTCATAAGTCTGAG
GCTGGTTTTGTGGAAGTATTGTTGGTTTGGTTTCCTTTGGGGGATGAAGGAGGAGGAAACAATTTTTTTTAAAAAAAAAGTGGGGGCAGG
CTGAAAGAGCAAAATCATCTTGAATTTTGTTGTCACATCGTGCCGGTGTTATAACCAGCTCTGTAGACTGCCGCACTGAAAACATTTCTG
TGAGAGAATCCTGCTGCATCACAGAAGCTGGAAGTTCTGATGTTCCACTGAAATCACAATGGAAAGTCTTGACTTGACTGGTAAGAGCTG
TTGTGAAGGTACATCTTACTTACTTACCTGGAAGCAGTGAGGCAGTCAAGAATTATGTGCTGTCAGAGCTGGTCTCAGCATGATCAAGGA
AGTGTGATCATTGGATATTTTTTTCTTGTCAATTTTATTATTTTTTAAAGTGTGACTTTTATTGATCTCCATTATCAAGTCACAGTAATG
AAAGGCAGTAATAGAAATAAGGATCATTCAGCAGAAGGAGAAGGGGTTGGAAAACGACCAAAACGAAAGTGTCTTCAGTGGCATCCATTG
CTAGCAAAGAAACTTCTTGATTTTTCAGAAGAGGAAGAAGAGGAAGACGAAGAGGAGGATATTGATAAGGTTCAACTTCTTGGGGCCGAT
GGCCTAGAGCAAGATGTTGGTGAAACTGAAGATGATGAATCACCAGAGCAGCGAGCCCGGAGACCAATGAATGCATTTCTTTTATTTTGC
AAACGCCATCGCTCTCTTGTACGTCAGGAACACCCCAGGCTTGATAACCGAGGTGCTACCAAGATACTAGCTGATTGGTGGGCTGTTCTT
GATCCAAAGGAAAAGCAGAAATACACAGACATGGCCAAGGAGTATAAGGATGCATTTATGAAAGCAAATCCTGGCTACAAATGGTGTCCT
ACCACAAACAAGCCTGTGAAATCCCCAACACCCACTGTCAATCCACGAAAGAAACTTTGGGCCTTCCCATCTGACTCTTCAAGAGACTTG
CCAAGCCCCAAGAAAGCAAAGACTGAAGAAATGCCTCAGCTTAACTTTGGAATGGCTGATCCTACTCAAATGGGAGGCCTGAGTATGCTG
CTGTTAGCTGGAGAACATGCTCTTGGCACACCAGAGGTATCCTCTGGCACATGCAGGCCTGATGTTTCAGAATCTCCTGAATTACGTCAG
AAGTCACCATTGTTTCAGTTTGCCGAGATATCTTCAAGTACGTCCCACTCTGATGCTTCTACAAAGCAGTGTCAAACATCTGCCTTGTTT
CAGTTTGCAGAGGGGGATTTTGGCACTCAAAAAGAAGCTGCTTGGGCCATAAGTAACTTAACAATTAGTGGAAGGAAAGATCAAGTGGCT
TACCTTATCCAACAAAATGTTATCCCACCTTTTTGCAACTTGCTGACTGTAAAAGATGCACAAGTTGTGCAAGTAGTACTCGATGGACTA
AGTAATATATTAAAAATGGCTGAAGATGAGGCAGAAACCATAGGCAATCTTATAGAAGAATGTGGAGGGCTGGAGAAAATTGAACAACTT
CAAAATCATGAAAATGAAGACATCTACAAATTGGCCTATGAGATCATTGATCAGTTCTTCTCTTCAGATGATATTGATGAAGACCCTAGC
CTTGTTCCAGAGGCAATTCAAGGCGGAACATTTGGTTTCAATTCATCTGCCAATGTACCAACAGAAGGGTTCCAGTTTTAGAAAGATGTT
GTGGAAGTTAGGTACAATGCAGCACTGAGATATATATATATATATGTGTGTGTGTATATATATATATATATACATATATATAAAAAGGTT
TGATCCATCAAGCTTGGCTCATGGGATCTGCTGCTGCATTAAATCGGGAAAGAAAATGTGAAGATTTCATTTGGAATCACAGAAAATGCC
CAAATGAGGTCAAGATGGCGAGTGGGTGCGAGTGAGAATGAGTGGCAAAATGTAATGAAAACTTTACATGAATGCTTATTTAGGTTGTTC
AAAGTAAAAAGGGCTACAGGTCACAGATCGTCAGTGCCTGAGAAAGAACATTGACTTACTCTATATCAATTGAGGGGAAAGTGCAGTACC
GTCATCTTCAAGCCTTGTAAGCATAAAAGAGAATAGGCTGCCCATATAAGTCAAAGGAAAATGAGCCCAGGCCTTGCTATGAAGCAGTGT
GTGAATGGACAATGTTGAATGAATGTCTGGCTCAGTGATGGAGAGCCAGGTTCATCTTTGAAATCTAGGGCTCTTCACTCATGAAGCAGA
CTCCTAGTCCTGGAGTGACTGTGTACGAGAGCGTGGTTGTGGTGCTGTATGTGAACGCATGCAAGCTTGATTCACCTTCAGGGGGCTGAT
AACCTAGTAAATCATCAAAATGAGATCATAAGTGTTAATGTACACTGGACATGAAAACAAAGACTGGTTTAGCAGCAGACATTGGTTTAC
TCTGCAGCCTGTGTTTTCTGTTTCCCCCTTTCCCACCTCCTTCCCCCCACCCAATCCTTTTTTTTTTCTTTTTTGCTTTTCTTTTCTTTT
TTTTTAGTTTTTATTTACTTTACCTAGTATGCCTTTTTTTAGTTGCTTCTCAAGTCAGAAAACTTTTCAGGAAGGTTTCCCTGTGCATTT
GCACCAGATGAATGTTTGATGCTATGAAAAGCTTTCCATATCATCAAAACTAATTTGTGTAGATTTTTGCATGAAAAAAATCATAAATTT
CCCTCAAAATAGACTGTGTTGCAGTACACAAGTTGCCATAATAGTATAAAACAGTAAAATGTGCTTAAAAGGCCATCCTTTTCATTTTCA
GAGATAACATAAAGATCTTTGCATGAGGTAAATCTACAGCATAGTTCATTTTTAGATTTTGTTGAGTCCTGTAAAGAAGAAGAAGAAAAA
AGTTTCAGTTGTGGTAGAATACCGTGCTGTGTTTAAATGTTACTTGTTTTCAAACTTTGTTTTCTATGAAAATGATATGGAAACTTCTAA
AATGGAATTTGGTGCATATGTACTGCTGAATAAAGACCGATGAAGAGGTTTGAGTAGATGTACAAATCAAGTAATGGTTTGAACACCTTT
AATAATATGCCTAATCTGTTCAATTGTTTTAGAATCTTTTTATCTTAGATGTAGGCAGCCATGAACAATCTATTTTGAGCCACTTTAGGG
AGAAAACTTTGTATTTTTAAAACTTGCATAAAAGTTATGCAAGTGGTTTTTATAAATTGGAATAATACCTCAGTTTTGAGGTTATGCACA
CTAAATTAAATGTGACATAAATTAATTTGTACAAAAAGAACTCTTTATAAGGTGGCTCATTGTAGGAAATCCTGTGCCTTCCCCTTTGAG
CACAAGTGTTGCATGAACAACAGTTTGCTATAAGAAACATACCAGATTAGCCACCATTAGCATCTATATCTACTTTGTGTTTAAAAATCA
ACTGGTAATTCTGAAACACTGTAGAATGGATAAAAATTATTTTGTGATCATAACTCTTTGTTGAACTAGAGTATTTTTGCAGCATTCCTT
GTCATCAGAAACATGGTTAAAGTTTAAAACTAGAAGCAGCAGAAAACTAGCTTGTAAAATTTATCCAAGTAGAGTGCAGGCTAGGCTGTC
TTGGGGAAATAAACATTAAAACTTAAAGCAATGTTTTACATGGGGTGTGTGTGTGTGGTGTGTGGATTTTTTTTTTTTTATAAAGTTAGA
GTATAATTCAATGGCTTACATTAGCTTCCTGTCTTTTTACCTAGAACCAGCATAATAAGAAATTTCTTTGGTTCTGTCATTTCAGTATGG
ACATATTAATATTTTAGCCCACTGAGTTTGTCCAGTTGACACCATCAGTGCTTCAGTTTTCTCTCTATCCAAAGCAAGGTTTTAACTTTC
CTTCATTCTCCAGTAAAACAGACCGAGACAACTTGAACTATATTTTGAGTATTGCTATATCTTCAACATATAGCTCCAAATGATGGATTG
TATACAAAGCATAGTACAGAAGGTTTCAGTAATTGGAAGGTGAACACAGCAATGCTTTACATAATTTGTGTTTTTTAGTAAAAAATATTG
GATTCAAAGTAAGCCAATGAGCTTGTATACAAATTTTATATACAAATTATTGTATAGAACAGTGATATGGAAAATAGGTAAGGGTGATAT
TAATATCTCTGGGTATAAGGACTACCTTATCGTTTAAATATTTTATTTCCATCTATAGCCTAATATAGAACATTGATTTTCTAGTAGAAA
TTCTGGGAAGGGCTTTTCTGTCTCTGAAATTGATTCAGTACAGTTGACAGTTCATCACGGTTACCTGGTTAAACACTTTTTTTTTTTTTT
TAATTCTCCAGTGATCTAGGAAATTGTTTCATTTTTAACACAGGCTTATTTCTGATGGGGATGGGGGCATAGAATAATATGCCTAATAAG
CTAAACGTTCTTAACGTTTCATGTCTTAAACTGTCTTTTTGAACATTGAGACCACCTCAAGTGCTGTAAAAATAAGAATGTTATATTAGG
GGTGTGTGAGACGCCCTAGTCTAAAATCTATCTTTAAATATATTTCCTTTGTAATTTTCAAAGACTTCAGTAATTGTGTGTTATGGTGGA
AATAATACTTTCCATTGGTCCACATTGCTCTGGACCAAACCTGGAGCATTTCTATAATTAGAGCTATCTATGAATCATTAAAAATGGATC
TAGAATAATTTTGGGGAGAGGGAGTGTATCATTTAGTTTAGGCTTACCTCAGCAGCACTTCATAGGGTGAGGAGTTGTTTGTTTCTTTAA
AGGTATAACTGCATTGTAAAATGACTGGGTTTATTGTAACAGTAATTTATGGGGGCACCCTTTTTGGATTCTCCATTGCCTCAGTTTCCT
CAAGGAAAAAGTTACAGAGATTAAGCTAAATTTTGAATTTAGAGAATAACTGCTGTGTAATTTTGGTATAATTACCATAAATTTAGTGTC
TTAAAACACAACATACATTATTTCACAATTTCTGTAGGTCAAGAGTGTAGTTAGGTTTTCTGCTCAGGGTCTCACAAGGCTGCAATAAAG
GTGTCAGCCAGAGCTGCAGTCTTATCTGAAGCTAGGGGGTCCTCTTTTATGCACATATGGCAAAATCCATTGCCTAGCAACTGAAGAAAT
CATGGGAACTTCTTCAAGGCCAGCAAGAGAATCTCTGATCTCAGGGAAGGCCTTAAGCGCTTTTTTAAAGGTCTCACCTGATTAGATCAG
GCCACCTACCCACCAGGGTGATCTCCCTTTTGATTAACCCAAAGCCAAACTGATGAGGTACCTTCATTACCCCTGCAAAATCCCTTCACC
TTTGCCCTGCATTGTAGTCCAATCACAGGGGTGATACGCATCATATTCAAAGATCCTGTTCACAGTCAAGGGAGGGGGTTATATGGAGTA
TGTATACCAGGGAATCTTGGGAGCCATCTTAAGAGTTCTTCCTATGACAAGGACTCAACTATTTAGAACTGGAACAATTTACAAGTGATA
GCCTTATATAGTTATCATAGCAAGCTTATTTGGGGATCAAGGTTGCCTCTGAGAACCTAATGAAAACTGGACCAGCTTCCCCAAAAAGTG
TATATACATGGTAGTTTTTCATACAGTTTTAGGGGATTCATAAGAGTCCATGAATTACAGTCTGTCCCAACCCTTCCCTTTAGATGATGA
GTTGTTGAGGTGACTTGCCCAAGGTCACACAGCTACTAAGGGCCAAATAAAGCCCACATCTCAACTCCCATACTGCCCAGGGCTTCTAAT
TACTATTCTAAAGGTAATCTAAATTCATTTAAATTTGTGAACCAATGCAAAAAAATGTGAATGTAGCTTTTTGGATATTTTTTTTGTTTA
CTAAGGAATGGGTAACATTGTTATAGAAGCTTGCCTAAGAGTTTTGAAATTAGTTGACCTTTTTGAGTTTCCAAAATTGAATCTTCCATT
GTAGCTATTAAAGTGAACTATAAATAGGCCAACTTTAATTGTTAACTCCTCGGGTTTGGTGGATTATCTACCATTTATATATAAAATTTC
AGTTAGAATCCACCATTGGCGTTTTGAAGGCCAAGATAGCTGAGTATCTTATCCTTTTTGTAACTTCTTGATTATTTTACTTATTGGCAA
AATTCATTAACTGTCAGCCAATAATTTAATATTATGGGAGGAAAAAATTTTGCCCAGATATCTGAGGCAATACTCCCAAACACTAACAAA
CTGATGCCTAACAAACTTGACATTTTGAACACTTAAAGTTTTCCCTAAACTTTTTAATAAGCACATTAATAAAGTATGCTTTTAAATATA
TATGTACAATAATTTTTAAAAGTTGCTGCAAGATGCCTTCAAATCAATATGCACGTTGGTGGCATTAGTGCAGTCTTCTATTTTTATTTT
TTTGAGACACAGTCTCGCTCTGTGGCCCAGGCTGGAGTGTAGTGGCGCAATCTCGGCTCACTGCAACCTCTGCCTCAAGGGTTCAAGCAA
TTCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGAGTACGCTACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAAATGGGGTTTCA
CCGTATTGGCCAGGCTGGTATTGGAATCCTGACCGCAAATGATCTGCCCACCTCGGCTTCCCAAAGTGCTGGGATTACAGGCGTGAGCCA
CTGCGCCCAACCAGCCTTAATTCTTAATAAAGGAAGTTGAAAAATAATGAACATTGGTAAAACTATTCTAGTGTGATCAGAAGCAAATTT
GGACTGTAGTGTCAAATTGATAAAAAACTAAGCACACCAATCATGTATAAGAAAAGTAGATTTAACATTTTTTTCCCTAAACACTTAACC
CAGAAGTTAACAATAATCTTGAAAATTCCTTTTAAATCCAGGCCCTTTAGGTGATGGCAGTTTGACTCAGGATGTCCAAGTCCAGTGTAT
TTTCAATAAAATTGACTTGACAGCTACTGCTCTGGGTGTAAGAGCAGTTGACTGTGAGGAAAAGTAAATGGTTCTACAGATTCTTTATGA
TCTACCTCCCACCAGAGGACTGCAGTACTCCCTTGTTATTTATATTTTCTGCCCCAATTTTTGCCTTCTCCACAAATTTTATACCTTTTG
TAGCTGCCTACTCCAGATTACTTCACCTTTCCAGACTATCAGTTCTTCCACTTTTATTCTTCATAAAGAAAATTCCAATAACCTGTTTCA
CTTAGGTTTTTCTATTACTCTTCAAGCATGAATCCTAATTTCCCTGACTATATCTTACCTCTGATCTCCATAACTGATGGATTCCTATCC
TAGACTATGTTACTCTAATATTACCCAAGATTTTCTCCAGCCTGTTTTTACTCTTACTTTGAAACAGCTGTTTAAAATGACTCGTAATCT
GCTTAAATCTACATGCTTTTTGTGGTTCTCAATCCAGTTACCTACCTTCCAGATAATTCCCTCACTGTCCTGTCCTCTCCATTCCTCTGA
TGTTTAAGCCCTGTGAGCCACCTTTCCCCCATCCTTTGTGCATAGTTACCATTTTACTCTTTCTTGTTGCCCAGGCAGGAATGCAGTGGT
GCCATCTTGGCTCACTGCAACCTCCACCTCCTAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACCACAAGCGTGCAC
CACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCACGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGATGAT
CCACCCTCCTTGGCCTCCCAAAGTGCTGGGATTGCAGGCGTGAGCCACCGCCTGGCCACCATTTTACTCTTTTTAGGTACAGTAATCTAA
TATCCAAAGTCTTGGACTCAGCTAAAGAGGGTATTTACCTTAAAAAAAAAAAAAAAAAGACTCCATCTTTTGATTCATAATTGTGGTGGG
GGCGGGGAATCAAGACAACCTTAGTCACTTTGGTATTACCATAATTCTTGTCTTTTCAGGGTTGTCCTGTTCAGCTGCATAAAACATCAT
GTATTCTAGGTATTTCCTACCTTCACTTACATTTTTACTTGCCGATGTGCTGCCTTCATAAATGGGTATATTCCGCCACACATCTAGTAA
GCCCCCAATGCAGTACACAATGTGTATCACTGATAAAACTCGCACTTCTGCCATGTCAGTATTATATTCAGTTGAGTGGTCTTTAGCATA
GTGGCAGTCCTAGTCATCCTAACCTTTTAGTTAAGGTAAAATTACATATGTTTATAGAACTCATATAGACAAGCTAGTTTTTAAAATCTT
CCTTTTAACCAGTTTAGGATGATCTAGGATAGCTAAGTTACCTACATGGTGACTGTTCGGTCTAATTCAGAAACAGAAGTACTAAAAGAA
TACTAAAAAGTTTTTACCCATTATCTCTATCCCTGTTTTCTTTTTGCAATTCTCAGCTGCAGGGAGCAAGAAAATACACAGCAGATAGGA
AATGTTTGTTTGCATCCTGGCTTTCTCAACCGCACTTTACGTCCTTGAATATTCTAGATATTTACTCCTTCAAGAAGTCAGGAGTATATC
CAGGCCTACCTATCATCCTTGCCATCCCCATTAACCCTCATTTTTCAGTATGTGTTTTACATTTATGGTTATTTTTCAGTCTATAGTATC
TGTTCACTCATTGCTCTATCACATCTGAGTTTCTCCGTCTTTCTTTCCACTAGATTGTAAGCTCCTTAAGGGCAAGGTCGGCATATAAGC

>9120_9120_3_BBX-KPNA4_BBX_chr3_107466886_ENST00000406780_KPNA4_chr3_160227659_ENST00000334256_length(amino acids)=417AA_BP=270
MKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRARRPMNAFLLF
CKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSDSSRD
LPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELRQKSPLFQFAEISSSTSHSDASTKQCQTSAL
FQFAEGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQ

--------------------------------------------------------------
>9120_9120_4_BBX-KPNA4_BBX_chr3_107466886_ENST00000415149_KPNA4_chr3_160227659_ENST00000334256_length(transcript)=8690nt_BP=1152nt
AAAATGAGTGTTTTCAGTCTCTCCGGGTTGCATGTACTGTATGTGGAGCAGTGTACAGTGAAGCGGAGGCAGAGCGGCTCCGCGAGCTTC
TCTCCACTTTCCCATAGAGAAACCCTGACTGGCCGCTGAGGGCTAGCTACACACACGCCCTCACGCCCGGCGAGCCCGCGAGGTCACTAT
CATATGACAAAGGCTTTGCCGCAGTTCATCTTCCTCCCTGTGTACTTTCCATTTGCCTTCCTGGAATCCTGCTGCATCACAGAAGCTGGA
AGTTCTGATGTTCCACTGAAATCACAATGGAAAGTCTTGACTTGACTGGTCACAGTAATGAAAGGCAGTAATAGAAATAAGGATCATTCA
GCAGAAGGAGAAGGGGTTGGAAAACGACCAAAACGAAAGTGTCTTCAGTGGCATCCATTGCTAGCAAAGAAACTTCTTGATTTTTCAGAA
GAGGAAGAAGAGGAAGACGAAGAGGAGGATATTGATAAGGTTCAACTTCTTGGGGCCGATGGCCTAGAGCAAGATGTTGGTGAAACTGAA
GATGATGAATCACCAGAGCAGCGAGCCCGGAGACCAATGAATGCATTTCTTTTATTTTGCAAACGCCATCGCTCTCTTGTACGTCAGGAA
CACCCCAGGCTTGATAACCGAGGTGCTACCAAGATACTAGCTGATTGGTGGGCTGTTCTTGATCCAAAGGAAAAGCAGAAATACACAGAC
ATGGCCAAGGAGTATAAGGATGCATTTATGAAAGCAAATCCTGGCTACAAATGGTGTCCTACCACAAACAAGCCTGTGAAATCCCCAACA
CCCACTGTCAATCCACGAAAGAAACTTTGGGCCTTCCCATCTGACTCTTCAAGAGACTTGCCAAGCCCCAAGAAAGCAAAGACTGAAGAA
ATGCCTCAGCTTAACTTTGGAATGGCTGATCCTACTCAAATGGGAGGCCTGAGTATGCTGCTGTTAGCTGGAGAACATGCTCTTGGCACA
CCAGAGGTATCCTCTGGCACATGCAGGCCTGATGTTTCAGAATCTCCTGAATTACGTCAGAAGTCACCATTGTTTCAGTTTGCCGAGATA
TCTTCAAGTACGTCCCACTCTGATGCTTCTACAAAGCAGTGTCAAACATCTGCCTTGTTTCAGTTTGCAGAGGGGGATTTTGGCACTCAA
AAAGAAGCTGCTTGGGCCATAAGTAACTTAACAATTAGTGGAAGGAAAGATCAAGTGGCTTACCTTATCCAACAAAATGTTATCCCACCT
TTTTGCAACTTGCTGACTGTAAAAGATGCACAAGTTGTGCAAGTAGTACTCGATGGACTAAGTAATATATTAAAAATGGCTGAAGATGAG
GCAGAAACCATAGGCAATCTTATAGAAGAATGTGGAGGGCTGGAGAAAATTGAACAACTTCAAAATCATGAAAATGAAGACATCTACAAA
TTGGCCTATGAGATCATTGATCAGTTCTTCTCTTCAGATGATATTGATGAAGACCCTAGCCTTGTTCCAGAGGCAATTCAAGGCGGAACA
TTTGGTTTCAATTCATCTGCCAATGTACCAACAGAAGGGTTCCAGTTTTAGAAAGATGTTGTGGAAGTTAGGTACAATGCAGCACTGAGA
TATATATATATATATGTGTGTGTGTATATATATATATATATACATATATATAAAAAGGTTTGATCCATCAAGCTTGGCTCATGGGATCTG
CTGCTGCATTAAATCGGGAAAGAAAATGTGAAGATTTCATTTGGAATCACAGAAAATGCCCAAATGAGGTCAAGATGGCGAGTGGGTGCG
AGTGAGAATGAGTGGCAAAATGTAATGAAAACTTTACATGAATGCTTATTTAGGTTGTTCAAAGTAAAAAGGGCTACAGGTCACAGATCG
TCAGTGCCTGAGAAAGAACATTGACTTACTCTATATCAATTGAGGGGAAAGTGCAGTACCGTCATCTTCAAGCCTTGTAAGCATAAAAGA
GAATAGGCTGCCCATATAAGTCAAAGGAAAATGAGCCCAGGCCTTGCTATGAAGCAGTGTGTGAATGGACAATGTTGAATGAATGTCTGG
CTCAGTGATGGAGAGCCAGGTTCATCTTTGAAATCTAGGGCTCTTCACTCATGAAGCAGACTCCTAGTCCTGGAGTGACTGTGTACGAGA
GCGTGGTTGTGGTGCTGTATGTGAACGCATGCAAGCTTGATTCACCTTCAGGGGGCTGATAACCTAGTAAATCATCAAAATGAGATCATA
AGTGTTAATGTACACTGGACATGAAAACAAAGACTGGTTTAGCAGCAGACATTGGTTTACTCTGCAGCCTGTGTTTTCTGTTTCCCCCTT
TCCCACCTCCTTCCCCCCACCCAATCCTTTTTTTTTTCTTTTTTGCTTTTCTTTTCTTTTTTTTTAGTTTTTATTTACTTTACCTAGTAT
GCCTTTTTTTAGTTGCTTCTCAAGTCAGAAAACTTTTCAGGAAGGTTTCCCTGTGCATTTGCACCAGATGAATGTTTGATGCTATGAAAA
GCTTTCCATATCATCAAAACTAATTTGTGTAGATTTTTGCATGAAAAAAATCATAAATTTCCCTCAAAATAGACTGTGTTGCAGTACACA
AGTTGCCATAATAGTATAAAACAGTAAAATGTGCTTAAAAGGCCATCCTTTTCATTTTCAGAGATAACATAAAGATCTTTGCATGAGGTA
AATCTACAGCATAGTTCATTTTTAGATTTTGTTGAGTCCTGTAAAGAAGAAGAAGAAAAAAGTTTCAGTTGTGGTAGAATACCGTGCTGT
GTTTAAATGTTACTTGTTTTCAAACTTTGTTTTCTATGAAAATGATATGGAAACTTCTAAAATGGAATTTGGTGCATATGTACTGCTGAA
TAAAGACCGATGAAGAGGTTTGAGTAGATGTACAAATCAAGTAATGGTTTGAACACCTTTAATAATATGCCTAATCTGTTCAATTGTTTT
AGAATCTTTTTATCTTAGATGTAGGCAGCCATGAACAATCTATTTTGAGCCACTTTAGGGAGAAAACTTTGTATTTTTAAAACTTGCATA
AAAGTTATGCAAGTGGTTTTTATAAATTGGAATAATACCTCAGTTTTGAGGTTATGCACACTAAATTAAATGTGACATAAATTAATTTGT
ACAAAAAGAACTCTTTATAAGGTGGCTCATTGTAGGAAATCCTGTGCCTTCCCCTTTGAGCACAAGTGTTGCATGAACAACAGTTTGCTA
TAAGAAACATACCAGATTAGCCACCATTAGCATCTATATCTACTTTGTGTTTAAAAATCAACTGGTAATTCTGAAACACTGTAGAATGGA
TAAAAATTATTTTGTGATCATAACTCTTTGTTGAACTAGAGTATTTTTGCAGCATTCCTTGTCATCAGAAACATGGTTAAAGTTTAAAAC
TAGAAGCAGCAGAAAACTAGCTTGTAAAATTTATCCAAGTAGAGTGCAGGCTAGGCTGTCTTGGGGAAATAAACATTAAAACTTAAAGCA
ATGTTTTACATGGGGTGTGTGTGTGTGGTGTGTGGATTTTTTTTTTTTTATAAAGTTAGAGTATAATTCAATGGCTTACATTAGCTTCCT
GTCTTTTTACCTAGAACCAGCATAATAAGAAATTTCTTTGGTTCTGTCATTTCAGTATGGACATATTAATATTTTAGCCCACTGAGTTTG
TCCAGTTGACACCATCAGTGCTTCAGTTTTCTCTCTATCCAAAGCAAGGTTTTAACTTTCCTTCATTCTCCAGTAAAACAGACCGAGACA
ACTTGAACTATATTTTGAGTATTGCTATATCTTCAACATATAGCTCCAAATGATGGATTGTATACAAAGCATAGTACAGAAGGTTTCAGT
AATTGGAAGGTGAACACAGCAATGCTTTACATAATTTGTGTTTTTTAGTAAAAAATATTGGATTCAAAGTAAGCCAATGAGCTTGTATAC
AAATTTTATATACAAATTATTGTATAGAACAGTGATATGGAAAATAGGTAAGGGTGATATTAATATCTCTGGGTATAAGGACTACCTTAT
CGTTTAAATATTTTATTTCCATCTATAGCCTAATATAGAACATTGATTTTCTAGTAGAAATTCTGGGAAGGGCTTTTCTGTCTCTGAAAT
TGATTCAGTACAGTTGACAGTTCATCACGGTTACCTGGTTAAACACTTTTTTTTTTTTTTTAATTCTCCAGTGATCTAGGAAATTGTTTC
ATTTTTAACACAGGCTTATTTCTGATGGGGATGGGGGCATAGAATAATATGCCTAATAAGCTAAACGTTCTTAACGTTTCATGTCTTAAA
CTGTCTTTTTGAACATTGAGACCACCTCAAGTGCTGTAAAAATAAGAATGTTATATTAGGGGTGTGTGAGACGCCCTAGTCTAAAATCTA
TCTTTAAATATATTTCCTTTGTAATTTTCAAAGACTTCAGTAATTGTGTGTTATGGTGGAAATAATACTTTCCATTGGTCCACATTGCTC
TGGACCAAACCTGGAGCATTTCTATAATTAGAGCTATCTATGAATCATTAAAAATGGATCTAGAATAATTTTGGGGAGAGGGAGTGTATC
ATTTAGTTTAGGCTTACCTCAGCAGCACTTCATAGGGTGAGGAGTTGTTTGTTTCTTTAAAGGTATAACTGCATTGTAAAATGACTGGGT
TTATTGTAACAGTAATTTATGGGGGCACCCTTTTTGGATTCTCCATTGCCTCAGTTTCCTCAAGGAAAAAGTTACAGAGATTAAGCTAAA
TTTTGAATTTAGAGAATAACTGCTGTGTAATTTTGGTATAATTACCATAAATTTAGTGTCTTAAAACACAACATACATTATTTCACAATT
TCTGTAGGTCAAGAGTGTAGTTAGGTTTTCTGCTCAGGGTCTCACAAGGCTGCAATAAAGGTGTCAGCCAGAGCTGCAGTCTTATCTGAA
GCTAGGGGGTCCTCTTTTATGCACATATGGCAAAATCCATTGCCTAGCAACTGAAGAAATCATGGGAACTTCTTCAAGGCCAGCAAGAGA
ATCTCTGATCTCAGGGAAGGCCTTAAGCGCTTTTTTAAAGGTCTCACCTGATTAGATCAGGCCACCTACCCACCAGGGTGATCTCCCTTT
TGATTAACCCAAAGCCAAACTGATGAGGTACCTTCATTACCCCTGCAAAATCCCTTCACCTTTGCCCTGCATTGTAGTCCAATCACAGGG
GTGATACGCATCATATTCAAAGATCCTGTTCACAGTCAAGGGAGGGGGTTATATGGAGTATGTATACCAGGGAATCTTGGGAGCCATCTT
AAGAGTTCTTCCTATGACAAGGACTCAACTATTTAGAACTGGAACAATTTACAAGTGATAGCCTTATATAGTTATCATAGCAAGCTTATT
TGGGGATCAAGGTTGCCTCTGAGAACCTAATGAAAACTGGACCAGCTTCCCCAAAAAGTGTATATACATGGTAGTTTTTCATACAGTTTT
AGGGGATTCATAAGAGTCCATGAATTACAGTCTGTCCCAACCCTTCCCTTTAGATGATGAGTTGTTGAGGTGACTTGCCCAAGGTCACAC
AGCTACTAAGGGCCAAATAAAGCCCACATCTCAACTCCCATACTGCCCAGGGCTTCTAATTACTATTCTAAAGGTAATCTAAATTCATTT
AAATTTGTGAACCAATGCAAAAAAATGTGAATGTAGCTTTTTGGATATTTTTTTTGTTTACTAAGGAATGGGTAACATTGTTATAGAAGC
TTGCCTAAGAGTTTTGAAATTAGTTGACCTTTTTGAGTTTCCAAAATTGAATCTTCCATTGTAGCTATTAAAGTGAACTATAAATAGGCC
AACTTTAATTGTTAACTCCTCGGGTTTGGTGGATTATCTACCATTTATATATAAAATTTCAGTTAGAATCCACCATTGGCGTTTTGAAGG
CCAAGATAGCTGAGTATCTTATCCTTTTTGTAACTTCTTGATTATTTTACTTATTGGCAAAATTCATTAACTGTCAGCCAATAATTTAAT
ATTATGGGAGGAAAAAATTTTGCCCAGATATCTGAGGCAATACTCCCAAACACTAACAAACTGATGCCTAACAAACTTGACATTTTGAAC
ACTTAAAGTTTTCCCTAAACTTTTTAATAAGCACATTAATAAAGTATGCTTTTAAATATATATGTACAATAATTTTTAAAAGTTGCTGCA
AGATGCCTTCAAATCAATATGCACGTTGGTGGCATTAGTGCAGTCTTCTATTTTTATTTTTTTGAGACACAGTCTCGCTCTGTGGCCCAG
GCTGGAGTGTAGTGGCGCAATCTCGGCTCACTGCAACCTCTGCCTCAAGGGTTCAAGCAATTCTGCCTCAGCCTCCTGAGTAGCTGGGAT
TACAGGAGTACGCTACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAAATGGGGTTTCACCGTATTGGCCAGGCTGGTATTGGAATCCT
GACCGCAAATGATCTGCCCACCTCGGCTTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCAACCAGCCTTAATTCTTAATAA
AGGAAGTTGAAAAATAATGAACATTGGTAAAACTATTCTAGTGTGATCAGAAGCAAATTTGGACTGTAGTGTCAAATTGATAAAAAACTA
AGCACACCAATCATGTATAAGAAAAGTAGATTTAACATTTTTTTCCCTAAACACTTAACCCAGAAGTTAACAATAATCTTGAAAATTCCT
TTTAAATCCAGGCCCTTTAGGTGATGGCAGTTTGACTCAGGATGTCCAAGTCCAGTGTATTTTCAATAAAATTGACTTGACAGCTACTGC
TCTGGGTGTAAGAGCAGTTGACTGTGAGGAAAAGTAAATGGTTCTACAGATTCTTTATGATCTACCTCCCACCAGAGGACTGCAGTACTC
CCTTGTTATTTATATTTTCTGCCCCAATTTTTGCCTTCTCCACAAATTTTATACCTTTTGTAGCTGCCTACTCCAGATTACTTCACCTTT
CCAGACTATCAGTTCTTCCACTTTTATTCTTCATAAAGAAAATTCCAATAACCTGTTTCACTTAGGTTTTTCTATTACTCTTCAAGCATG
AATCCTAATTTCCCTGACTATATCTTACCTCTGATCTCCATAACTGATGGATTCCTATCCTAGACTATGTTACTCTAATATTACCCAAGA
TTTTCTCCAGCCTGTTTTTACTCTTACTTTGAAACAGCTGTTTAAAATGACTCGTAATCTGCTTAAATCTACATGCTTTTTGTGGTTCTC
AATCCAGTTACCTACCTTCCAGATAATTCCCTCACTGTCCTGTCCTCTCCATTCCTCTGATGTTTAAGCCCTGTGAGCCACCTTTCCCCC
ATCCTTTGTGCATAGTTACCATTTTACTCTTTCTTGTTGCCCAGGCAGGAATGCAGTGGTGCCATCTTGGCTCACTGCAACCTCCACCTC
CTAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACCACAAGCGTGCACCACCACGCCCGGCTAATTTTTGTATTTTTA
GTAGAGATGGGGTTTCACCACGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGATGATCCACCCTCCTTGGCCTCCCAAAGTGCTGGG
ATTGCAGGCGTGAGCCACCGCCTGGCCACCATTTTACTCTTTTTAGGTACAGTAATCTAATATCCAAAGTCTTGGACTCAGCTAAAGAGG
GTATTTACCTTAAAAAAAAAAAAAAAAAGACTCCATCTTTTGATTCATAATTGTGGTGGGGGCGGGGAATCAAGACAACCTTAGTCACTT
TGGTATTACCATAATTCTTGTCTTTTCAGGGTTGTCCTGTTCAGCTGCATAAAACATCATGTATTCTAGGTATTTCCTACCTTCACTTAC
ATTTTTACTTGCCGATGTGCTGCCTTCATAAATGGGTATATTCCGCCACACATCTAGTAAGCCCCCAATGCAGTACACAATGTGTATCAC
TGATAAAACTCGCACTTCTGCCATGTCAGTATTATATTCAGTTGAGTGGTCTTTAGCATAGTGGCAGTCCTAGTCATCCTAACCTTTTAG
TTAAGGTAAAATTACATATGTTTATAGAACTCATATAGACAAGCTAGTTTTTAAAATCTTCCTTTTAACCAGTTTAGGATGATCTAGGAT
AGCTAAGTTACCTACATGGTGACTGTTCGGTCTAATTCAGAAACAGAAGTACTAAAAGAATACTAAAAAGTTTTTACCCATTATCTCTAT
CCCTGTTTTCTTTTTGCAATTCTCAGCTGCAGGGAGCAAGAAAATACACAGCAGATAGGAAATGTTTGTTTGCATCCTGGCTTTCTCAAC
CGCACTTTACGTCCTTGAATATTCTAGATATTTACTCCTTCAAGAAGTCAGGAGTATATCCAGGCCTACCTATCATCCTTGCCATCCCCA
TTAACCCTCATTTTTCAGTATGTGTTTTACATTTATGGTTATTTTTCAGTCTATAGTATCTGTTCACTCATTGCTCTATCACATCTGAGT
TTCTCCGTCTTTCTTTCCACTAGATTGTAAGCTCCTTAAGGGCAAGGTCGGCATATAAGCAAAGTTCTGTAAACACCGTGAAGGTACCAT

>9120_9120_4_BBX-KPNA4_BBX_chr3_107466886_ENST00000415149_KPNA4_chr3_160227659_ENST00000334256_length(amino acids)=421AA_BP=274
MVTVMKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRARRPMNA
FLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSD
SSRDLPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELRQKSPLFQFAEISSSTSHSDASTKQCQ
TSALFQFAEGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLE

--------------------------------------------------------------
>9120_9120_5_BBX-KPNA4_BBX_chr3_107466886_ENST00000416476_KPNA4_chr3_160227659_ENST00000334256_length(transcript)=8583nt_BP=1045nt
AGAAACCCTGACTGGCCGCTGAGGGCTAGCTACACACACGCCCTCACGCCCGGCGAGCCCGCGAGGTCACTATCATATGACAAAGGCTTT
GCCGCAGTTCATCTTCCTCCCTGTGTACTTTCCATTTGCCTTCCTGGAATCCTGCTGCATCACAGAAGCTGGAAGTTCTGATGTTCCACT
GAAATCACAATGGAAAGTCTTGACTTGACTGGTCACAGTAATGAAAGGCAGTAATAGAAATAAGGATCATTCAGCAGAAGGAGAAGGGGT
TGGAAAACGACCAAAACGAAAGTGTCTTCAGTGGCATCCATTGCTAGCAAAGAAACTTCTTGATTTTTCAGAAGAGGAAGAAGAGGAAGA
CGAAGAGGAGGATATTGATAAGGTTCAACTTCTTGGGGCCGATGGCCTAGAGCAAGATGTTGGTGAAACTGAAGATGATGAATCACCAGA
GCAGCGAGCCCGGAGACCAATGAATGCATTTCTTTTATTTTGCAAACGCCATCGCTCTCTTGTACGTCAGGAACACCCCAGGCTTGATAA
CCGAGGTGCTACCAAGATACTAGCTGATTGGTGGGCTGTTCTTGATCCAAAGGAAAAGCAGAAATACACAGACATGGCCAAGGAGTATAA
GGATGCATTTATGAAAGCAAATCCTGGCTACAAATGGTGTCCTACCACAAACAAGCCTGTGAAATCCCCAACACCCACTGTCAATCCACG
AAAGAAACTTTGGGCCTTCCCATCTGACTCTTCAAGAGACTTGCCAAGCCCCAAGAAAGCAAAGACTGAAGAAATGCCTCAGCTTAACTT
TGGAATGGCTGATCCTACTCAAATGGGAGGCCTGAGTATGCTGCTGTTAGCTGGAGAACATGCTCTTGGCACACCAGAGGTATCCTCTGG
CACATGCAGGCCTGATGTTTCAGAATCTCCTGAATTACGTCAGAAGTCACCATTGTTTCAGTTTGCCGAGATATCTTCAAGTACGTCCCA
CTCTGATGCTTCTACAAAGCAGTGTCAAACATCTGCCTTGTTTCAGTTTGCAGAGGGGGATTTTGGCACTCAAAAAGAAGCTGCTTGGGC
CATAAGTAACTTAACAATTAGTGGAAGGAAAGATCAAGTGGCTTACCTTATCCAACAAAATGTTATCCCACCTTTTTGCAACTTGCTGAC
TGTAAAAGATGCACAAGTTGTGCAAGTAGTACTCGATGGACTAAGTAATATATTAAAAATGGCTGAAGATGAGGCAGAAACCATAGGCAA
TCTTATAGAAGAATGTGGAGGGCTGGAGAAAATTGAACAACTTCAAAATCATGAAAATGAAGACATCTACAAATTGGCCTATGAGATCAT
TGATCAGTTCTTCTCTTCAGATGATATTGATGAAGACCCTAGCCTTGTTCCAGAGGCAATTCAAGGCGGAACATTTGGTTTCAATTCATC
TGCCAATGTACCAACAGAAGGGTTCCAGTTTTAGAAAGATGTTGTGGAAGTTAGGTACAATGCAGCACTGAGATATATATATATATATGT
GTGTGTGTATATATATATATATATACATATATATAAAAAGGTTTGATCCATCAAGCTTGGCTCATGGGATCTGCTGCTGCATTAAATCGG
GAAAGAAAATGTGAAGATTTCATTTGGAATCACAGAAAATGCCCAAATGAGGTCAAGATGGCGAGTGGGTGCGAGTGAGAATGAGTGGCA
AAATGTAATGAAAACTTTACATGAATGCTTATTTAGGTTGTTCAAAGTAAAAAGGGCTACAGGTCACAGATCGTCAGTGCCTGAGAAAGA
ACATTGACTTACTCTATATCAATTGAGGGGAAAGTGCAGTACCGTCATCTTCAAGCCTTGTAAGCATAAAAGAGAATAGGCTGCCCATAT
AAGTCAAAGGAAAATGAGCCCAGGCCTTGCTATGAAGCAGTGTGTGAATGGACAATGTTGAATGAATGTCTGGCTCAGTGATGGAGAGCC
AGGTTCATCTTTGAAATCTAGGGCTCTTCACTCATGAAGCAGACTCCTAGTCCTGGAGTGACTGTGTACGAGAGCGTGGTTGTGGTGCTG
TATGTGAACGCATGCAAGCTTGATTCACCTTCAGGGGGCTGATAACCTAGTAAATCATCAAAATGAGATCATAAGTGTTAATGTACACTG
GACATGAAAACAAAGACTGGTTTAGCAGCAGACATTGGTTTACTCTGCAGCCTGTGTTTTCTGTTTCCCCCTTTCCCACCTCCTTCCCCC
CACCCAATCCTTTTTTTTTTCTTTTTTGCTTTTCTTTTCTTTTTTTTTAGTTTTTATTTACTTTACCTAGTATGCCTTTTTTTAGTTGCT
TCTCAAGTCAGAAAACTTTTCAGGAAGGTTTCCCTGTGCATTTGCACCAGATGAATGTTTGATGCTATGAAAAGCTTTCCATATCATCAA
AACTAATTTGTGTAGATTTTTGCATGAAAAAAATCATAAATTTCCCTCAAAATAGACTGTGTTGCAGTACACAAGTTGCCATAATAGTAT
AAAACAGTAAAATGTGCTTAAAAGGCCATCCTTTTCATTTTCAGAGATAACATAAAGATCTTTGCATGAGGTAAATCTACAGCATAGTTC
ATTTTTAGATTTTGTTGAGTCCTGTAAAGAAGAAGAAGAAAAAAGTTTCAGTTGTGGTAGAATACCGTGCTGTGTTTAAATGTTACTTGT
TTTCAAACTTTGTTTTCTATGAAAATGATATGGAAACTTCTAAAATGGAATTTGGTGCATATGTACTGCTGAATAAAGACCGATGAAGAG
GTTTGAGTAGATGTACAAATCAAGTAATGGTTTGAACACCTTTAATAATATGCCTAATCTGTTCAATTGTTTTAGAATCTTTTTATCTTA
GATGTAGGCAGCCATGAACAATCTATTTTGAGCCACTTTAGGGAGAAAACTTTGTATTTTTAAAACTTGCATAAAAGTTATGCAAGTGGT
TTTTATAAATTGGAATAATACCTCAGTTTTGAGGTTATGCACACTAAATTAAATGTGACATAAATTAATTTGTACAAAAAGAACTCTTTA
TAAGGTGGCTCATTGTAGGAAATCCTGTGCCTTCCCCTTTGAGCACAAGTGTTGCATGAACAACAGTTTGCTATAAGAAACATACCAGAT
TAGCCACCATTAGCATCTATATCTACTTTGTGTTTAAAAATCAACTGGTAATTCTGAAACACTGTAGAATGGATAAAAATTATTTTGTGA
TCATAACTCTTTGTTGAACTAGAGTATTTTTGCAGCATTCCTTGTCATCAGAAACATGGTTAAAGTTTAAAACTAGAAGCAGCAGAAAAC
TAGCTTGTAAAATTTATCCAAGTAGAGTGCAGGCTAGGCTGTCTTGGGGAAATAAACATTAAAACTTAAAGCAATGTTTTACATGGGGTG
TGTGTGTGTGGTGTGTGGATTTTTTTTTTTTTATAAAGTTAGAGTATAATTCAATGGCTTACATTAGCTTCCTGTCTTTTTACCTAGAAC
CAGCATAATAAGAAATTTCTTTGGTTCTGTCATTTCAGTATGGACATATTAATATTTTAGCCCACTGAGTTTGTCCAGTTGACACCATCA
GTGCTTCAGTTTTCTCTCTATCCAAAGCAAGGTTTTAACTTTCCTTCATTCTCCAGTAAAACAGACCGAGACAACTTGAACTATATTTTG
AGTATTGCTATATCTTCAACATATAGCTCCAAATGATGGATTGTATACAAAGCATAGTACAGAAGGTTTCAGTAATTGGAAGGTGAACAC
AGCAATGCTTTACATAATTTGTGTTTTTTAGTAAAAAATATTGGATTCAAAGTAAGCCAATGAGCTTGTATACAAATTTTATATACAAAT
TATTGTATAGAACAGTGATATGGAAAATAGGTAAGGGTGATATTAATATCTCTGGGTATAAGGACTACCTTATCGTTTAAATATTTTATT
TCCATCTATAGCCTAATATAGAACATTGATTTTCTAGTAGAAATTCTGGGAAGGGCTTTTCTGTCTCTGAAATTGATTCAGTACAGTTGA
CAGTTCATCACGGTTACCTGGTTAAACACTTTTTTTTTTTTTTTAATTCTCCAGTGATCTAGGAAATTGTTTCATTTTTAACACAGGCTT
ATTTCTGATGGGGATGGGGGCATAGAATAATATGCCTAATAAGCTAAACGTTCTTAACGTTTCATGTCTTAAACTGTCTTTTTGAACATT
GAGACCACCTCAAGTGCTGTAAAAATAAGAATGTTATATTAGGGGTGTGTGAGACGCCCTAGTCTAAAATCTATCTTTAAATATATTTCC
TTTGTAATTTTCAAAGACTTCAGTAATTGTGTGTTATGGTGGAAATAATACTTTCCATTGGTCCACATTGCTCTGGACCAAACCTGGAGC
ATTTCTATAATTAGAGCTATCTATGAATCATTAAAAATGGATCTAGAATAATTTTGGGGAGAGGGAGTGTATCATTTAGTTTAGGCTTAC
CTCAGCAGCACTTCATAGGGTGAGGAGTTGTTTGTTTCTTTAAAGGTATAACTGCATTGTAAAATGACTGGGTTTATTGTAACAGTAATT
TATGGGGGCACCCTTTTTGGATTCTCCATTGCCTCAGTTTCCTCAAGGAAAAAGTTACAGAGATTAAGCTAAATTTTGAATTTAGAGAAT
AACTGCTGTGTAATTTTGGTATAATTACCATAAATTTAGTGTCTTAAAACACAACATACATTATTTCACAATTTCTGTAGGTCAAGAGTG
TAGTTAGGTTTTCTGCTCAGGGTCTCACAAGGCTGCAATAAAGGTGTCAGCCAGAGCTGCAGTCTTATCTGAAGCTAGGGGGTCCTCTTT
TATGCACATATGGCAAAATCCATTGCCTAGCAACTGAAGAAATCATGGGAACTTCTTCAAGGCCAGCAAGAGAATCTCTGATCTCAGGGA
AGGCCTTAAGCGCTTTTTTAAAGGTCTCACCTGATTAGATCAGGCCACCTACCCACCAGGGTGATCTCCCTTTTGATTAACCCAAAGCCA
AACTGATGAGGTACCTTCATTACCCCTGCAAAATCCCTTCACCTTTGCCCTGCATTGTAGTCCAATCACAGGGGTGATACGCATCATATT
CAAAGATCCTGTTCACAGTCAAGGGAGGGGGTTATATGGAGTATGTATACCAGGGAATCTTGGGAGCCATCTTAAGAGTTCTTCCTATGA
CAAGGACTCAACTATTTAGAACTGGAACAATTTACAAGTGATAGCCTTATATAGTTATCATAGCAAGCTTATTTGGGGATCAAGGTTGCC
TCTGAGAACCTAATGAAAACTGGACCAGCTTCCCCAAAAAGTGTATATACATGGTAGTTTTTCATACAGTTTTAGGGGATTCATAAGAGT
CCATGAATTACAGTCTGTCCCAACCCTTCCCTTTAGATGATGAGTTGTTGAGGTGACTTGCCCAAGGTCACACAGCTACTAAGGGCCAAA
TAAAGCCCACATCTCAACTCCCATACTGCCCAGGGCTTCTAATTACTATTCTAAAGGTAATCTAAATTCATTTAAATTTGTGAACCAATG
CAAAAAAATGTGAATGTAGCTTTTTGGATATTTTTTTTGTTTACTAAGGAATGGGTAACATTGTTATAGAAGCTTGCCTAAGAGTTTTGA
AATTAGTTGACCTTTTTGAGTTTCCAAAATTGAATCTTCCATTGTAGCTATTAAAGTGAACTATAAATAGGCCAACTTTAATTGTTAACT
CCTCGGGTTTGGTGGATTATCTACCATTTATATATAAAATTTCAGTTAGAATCCACCATTGGCGTTTTGAAGGCCAAGATAGCTGAGTAT
CTTATCCTTTTTGTAACTTCTTGATTATTTTACTTATTGGCAAAATTCATTAACTGTCAGCCAATAATTTAATATTATGGGAGGAAAAAA
TTTTGCCCAGATATCTGAGGCAATACTCCCAAACACTAACAAACTGATGCCTAACAAACTTGACATTTTGAACACTTAAAGTTTTCCCTA
AACTTTTTAATAAGCACATTAATAAAGTATGCTTTTAAATATATATGTACAATAATTTTTAAAAGTTGCTGCAAGATGCCTTCAAATCAA
TATGCACGTTGGTGGCATTAGTGCAGTCTTCTATTTTTATTTTTTTGAGACACAGTCTCGCTCTGTGGCCCAGGCTGGAGTGTAGTGGCG
CAATCTCGGCTCACTGCAACCTCTGCCTCAAGGGTTCAAGCAATTCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGAGTACGCTACC
ACGCCTGGCTAATTTTTGTATTTTTAGTAGAAATGGGGTTTCACCGTATTGGCCAGGCTGGTATTGGAATCCTGACCGCAAATGATCTGC
CCACCTCGGCTTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCAACCAGCCTTAATTCTTAATAAAGGAAGTTGAAAAATAA
TGAACATTGGTAAAACTATTCTAGTGTGATCAGAAGCAAATTTGGACTGTAGTGTCAAATTGATAAAAAACTAAGCACACCAATCATGTA
TAAGAAAAGTAGATTTAACATTTTTTTCCCTAAACACTTAACCCAGAAGTTAACAATAATCTTGAAAATTCCTTTTAAATCCAGGCCCTT
TAGGTGATGGCAGTTTGACTCAGGATGTCCAAGTCCAGTGTATTTTCAATAAAATTGACTTGACAGCTACTGCTCTGGGTGTAAGAGCAG
TTGACTGTGAGGAAAAGTAAATGGTTCTACAGATTCTTTATGATCTACCTCCCACCAGAGGACTGCAGTACTCCCTTGTTATTTATATTT
TCTGCCCCAATTTTTGCCTTCTCCACAAATTTTATACCTTTTGTAGCTGCCTACTCCAGATTACTTCACCTTTCCAGACTATCAGTTCTT
CCACTTTTATTCTTCATAAAGAAAATTCCAATAACCTGTTTCACTTAGGTTTTTCTATTACTCTTCAAGCATGAATCCTAATTTCCCTGA
CTATATCTTACCTCTGATCTCCATAACTGATGGATTCCTATCCTAGACTATGTTACTCTAATATTACCCAAGATTTTCTCCAGCCTGTTT
TTACTCTTACTTTGAAACAGCTGTTTAAAATGACTCGTAATCTGCTTAAATCTACATGCTTTTTGTGGTTCTCAATCCAGTTACCTACCT
TCCAGATAATTCCCTCACTGTCCTGTCCTCTCCATTCCTCTGATGTTTAAGCCCTGTGAGCCACCTTTCCCCCATCCTTTGTGCATAGTT
ACCATTTTACTCTTTCTTGTTGCCCAGGCAGGAATGCAGTGGTGCCATCTTGGCTCACTGCAACCTCCACCTCCTAGGTTCAAGCGATTC
TCCTGCCTCAGCCTCCTGAGTAGCTGGGACCACAAGCGTGCACCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCA
CCACGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGATGATCCACCCTCCTTGGCCTCCCAAAGTGCTGGGATTGCAGGCGTGAGCCA
CCGCCTGGCCACCATTTTACTCTTTTTAGGTACAGTAATCTAATATCCAAAGTCTTGGACTCAGCTAAAGAGGGTATTTACCTTAAAAAA
AAAAAAAAAAAGACTCCATCTTTTGATTCATAATTGTGGTGGGGGCGGGGAATCAAGACAACCTTAGTCACTTTGGTATTACCATAATTC
TTGTCTTTTCAGGGTTGTCCTGTTCAGCTGCATAAAACATCATGTATTCTAGGTATTTCCTACCTTCACTTACATTTTTACTTGCCGATG
TGCTGCCTTCATAAATGGGTATATTCCGCCACACATCTAGTAAGCCCCCAATGCAGTACACAATGTGTATCACTGATAAAACTCGCACTT
CTGCCATGTCAGTATTATATTCAGTTGAGTGGTCTTTAGCATAGTGGCAGTCCTAGTCATCCTAACCTTTTAGTTAAGGTAAAATTACAT
ATGTTTATAGAACTCATATAGACAAGCTAGTTTTTAAAATCTTCCTTTTAACCAGTTTAGGATGATCTAGGATAGCTAAGTTACCTACAT
GGTGACTGTTCGGTCTAATTCAGAAACAGAAGTACTAAAAGAATACTAAAAAGTTTTTACCCATTATCTCTATCCCTGTTTTCTTTTTGC
AATTCTCAGCTGCAGGGAGCAAGAAAATACACAGCAGATAGGAAATGTTTGTTTGCATCCTGGCTTTCTCAACCGCACTTTACGTCCTTG
AATATTCTAGATATTTACTCCTTCAAGAAGTCAGGAGTATATCCAGGCCTACCTATCATCCTTGCCATCCCCATTAACCCTCATTTTTCA
GTATGTGTTTTACATTTATGGTTATTTTTCAGTCTATAGTATCTGTTCACTCATTGCTCTATCACATCTGAGTTTCTCCGTCTTTCTTTC
CACTAGATTGTAAGCTCCTTAAGGGCAAGGTCGGCATATAAGCAAAGTTCTGTAAACACCGTGAAGGTACCATGAGTTCTATGGGTACTC

>9120_9120_5_BBX-KPNA4_BBX_chr3_107466886_ENST00000416476_KPNA4_chr3_160227659_ENST00000334256_length(amino acids)=421AA_BP=274
MVTVMKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRARRPMNA
FLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSD
SSRDLPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELRQKSPLFQFAEISSSTSHSDASTKQCQ
TSALFQFAEGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLE

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Fusion Gene PPI Analysis for BBX-KPNA4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BBX-KPNA4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BBX-KPNA4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource