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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:TMEM189-KCNC3 (FusionGDB2 ID:91845) |
Fusion Gene Summary for TMEM189-KCNC3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TMEM189-KCNC3 | Fusion gene ID: 91845 | Hgene | Tgene | Gene symbol | TMEM189 | KCNC3 | Gene ID | 387521 | 3748 |
| Gene name | transmembrane protein 189 | potassium voltage-gated channel subfamily C member 3 | |
| Synonyms | CarF|KUA | KSHIIID|KV3.3|SCA13 | |
| Cytomap | 20q13.13 | 19q13.33 | |
| Type of gene | protein-coding | protein-coding | |
| Description | transmembrane protein 189 | potassium voltage-gated channel subfamily C member 3Shaw-related voltage-gated potassium channel protein 3potassium channel, voltage gated Shaw related subfamily C, member 3potassium voltage-gated channel, Shaw-related subfamily, member 3voltage-gated | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | Q14003 | |
| Ensembl transtripts involved in fusion gene | ENST00000371650, ENST00000371652, ENST00000557021, ENST00000371656, | ENST00000391818, ENST00000474951, ENST00000477616, ENST00000376959, | |
| Fusion gene scores | * DoF score | 7 X 9 X 6=378 | 2 X 2 X 2=8 |
| # samples | 8 | 3 | |
| ** MAII score | log2(8/378*10)=-2.24031432933371 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/8*10)=1.90689059560852 | |
| Context | PubMed: TMEM189 [Title/Abstract] AND KCNC3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | TMEM189(48770054)-KCNC3(50827339), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | TMEM189 | GO:0008611 | ether lipid biosynthetic process | 31604315 |
| Tgene | KCNC3 | GO:0051262 | protein tetramerization | 23734863 |
| Fusion gene breakpoints across TMEM189 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across KCNC3 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BRCA | TCGA-D8-A1XD-01A | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| ChimerDB4 | BRCA | TCGA-D8-A1XD-01A | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| ChimerDB4 | BRCA | TCGA-D8-A1XD | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| ChimerDB4 | BRCA | TCGA-D8-A1XD | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
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Fusion Gene ORF analysis for TMEM189-KCNC3 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000371650 | ENST00000391818 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000371650 | ENST00000391818 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000371650 | ENST00000474951 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000371650 | ENST00000474951 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000371650 | ENST00000477616 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000371650 | ENST00000477616 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000371652 | ENST00000391818 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000371652 | ENST00000391818 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000371652 | ENST00000474951 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000371652 | ENST00000474951 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000371652 | ENST00000477616 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000371652 | ENST00000477616 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000557021 | ENST00000391818 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000557021 | ENST00000391818 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000557021 | ENST00000474951 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000557021 | ENST00000474951 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000557021 | ENST00000477616 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| 5CDS-intron | ENST00000557021 | ENST00000477616 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| In-frame | ENST00000371650 | ENST00000376959 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| In-frame | ENST00000371650 | ENST00000376959 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| In-frame | ENST00000371652 | ENST00000376959 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| In-frame | ENST00000371652 | ENST00000376959 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| In-frame | ENST00000557021 | ENST00000376959 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| In-frame | ENST00000557021 | ENST00000376959 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| intron-3CDS | ENST00000371650 | ENST00000376959 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-3CDS | ENST00000371650 | ENST00000376959 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| intron-3CDS | ENST00000371652 | ENST00000376959 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-3CDS | ENST00000371652 | ENST00000376959 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| intron-3CDS | ENST00000371656 | ENST00000376959 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-3CDS | ENST00000371656 | ENST00000376959 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| intron-3CDS | ENST00000371656 | ENST00000376959 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| intron-3CDS | ENST00000371656 | ENST00000376959 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| intron-3CDS | ENST00000557021 | ENST00000376959 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-3CDS | ENST00000557021 | ENST00000376959 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371650 | ENST00000391818 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371650 | ENST00000391818 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371650 | ENST00000474951 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371650 | ENST00000474951 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371650 | ENST00000477616 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371650 | ENST00000477616 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371652 | ENST00000391818 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371652 | ENST00000391818 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371652 | ENST00000474951 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371652 | ENST00000474951 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371652 | ENST00000477616 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371652 | ENST00000477616 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371656 | ENST00000391818 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371656 | ENST00000391818 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371656 | ENST00000391818 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371656 | ENST00000391818 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371656 | ENST00000474951 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371656 | ENST00000474951 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371656 | ENST00000474951 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371656 | ENST00000474951 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371656 | ENST00000477616 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371656 | ENST00000477616 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371656 | ENST00000477616 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000371656 | ENST00000477616 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000557021 | ENST00000391818 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000557021 | ENST00000391818 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000557021 | ENST00000474951 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000557021 | ENST00000474951 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000557021 | ENST00000477616 | TMEM189 | chr20 | 48767749 | - | KCNC3 | chr19 | 50827339 | - |
| intron-intron | ENST00000557021 | ENST00000477616 | TMEM189 | chr20 | 48767748 | - | KCNC3 | chr19 | 50827339 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000557021 | TMEM189 | chr20 | 48770054 | - | ENST00000376959 | KCNC3 | chr19 | 50827339 | - | 4695 | 282 | 1640 | 0 | 547 |
| ENST00000371650 | TMEM189 | chr20 | 48770054 | - | ENST00000376959 | KCNC3 | chr19 | 50827339 | - | 4631 | 218 | 1576 | 2 | 525 |
| ENST00000371652 | TMEM189 | chr20 | 48770054 | - | ENST00000376959 | KCNC3 | chr19 | 50827339 | - | 4631 | 218 | 1576 | 2 | 525 |
| ENST00000557021 | TMEM189 | chr20 | 48770053 | - | ENST00000376959 | KCNC3 | chr19 | 50827339 | - | 4695 | 282 | 1640 | 0 | 547 |
| ENST00000371650 | TMEM189 | chr20 | 48770053 | - | ENST00000376959 | KCNC3 | chr19 | 50827339 | - | 4631 | 218 | 1576 | 2 | 525 |
| ENST00000371652 | TMEM189 | chr20 | 48770053 | - | ENST00000376959 | KCNC3 | chr19 | 50827339 | - | 4631 | 218 | 1576 | 2 | 525 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000557021 | ENST00000376959 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - | 0.026603764 | 0.97339624 |
| ENST00000371650 | ENST00000376959 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - | 0.02717372 | 0.9728263 |
| ENST00000371652 | ENST00000376959 | TMEM189 | chr20 | 48770054 | - | KCNC3 | chr19 | 50827339 | - | 0.02717372 | 0.9728263 |
| ENST00000557021 | ENST00000376959 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - | 0.026603764 | 0.97339624 |
| ENST00000371650 | ENST00000376959 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - | 0.02717372 | 0.9728263 |
| ENST00000371652 | ENST00000376959 | TMEM189 | chr20 | 48770053 | - | KCNC3 | chr19 | 50827339 | - | 0.02717372 | 0.9728263 |
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Fusion Genomic Features for TMEM189-KCNC3 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for TMEM189-KCNC3 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:48770054/chr19:50827339) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | KCNC3 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient. The channel displays rapid activation and inactivation kinetics (PubMed:10712820, PubMed:26997484, PubMed:22289912, PubMed:23734863, PubMed:16501573, PubMed:19953606, PubMed:21479265, PubMed:25756792). It plays a role in the regulation of the frequency, shape and duration of action potentials in Purkinje cells. Required for normal survival of cerebellar neurons, probably via its role in regulating the duration and frequency of action potentials that in turn regulate the activity of voltage-gated Ca(2+) channels and cellular Ca(2+) homeostasis (By similarity). Required for normal motor function (PubMed:23734863, PubMed:16501573, PubMed:19953606, PubMed:21479265, PubMed:25756792). Plays a role in the reorganization of the cortical actin cytoskeleton and the formation of actin veil structures in neuronal growth cones via its interaction with HAX1 and the Arp2/3 complex (PubMed:26997484). {ECO:0000250|UniProtKB:Q63959, ECO:0000269|PubMed:10712820, ECO:0000269|PubMed:16501573, ECO:0000269|PubMed:19953606, ECO:0000269|PubMed:21479265, ECO:0000269|PubMed:22289912, ECO:0000269|PubMed:23734863, ECO:0000269|PubMed:25756792, ECO:0000269|PubMed:26997484}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 577_587 | 290 | 237.33333333333334 | Compositional bias | Note=Poly-Pro | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 596_599 | 290 | 237.33333333333334 | Compositional bias | Note=Poly-Pro | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 668_673 | 290 | 237.33333333333334 | Compositional bias | Note=Poly-Ala | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 577_587 | 290 | 237.33333333333334 | Compositional bias | Note=Poly-Pro | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 596_599 | 290 | 237.33333333333334 | Compositional bias | Note=Poly-Pro | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 668_673 | 290 | 237.33333333333334 | Compositional bias | Note=Poly-Ala | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 503_508 | 290 | 237.33333333333334 | Motif | Selectivity filter | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 503_508 | 290 | 237.33333333333334 | Motif | Selectivity filter | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 371_379 | 290 | 237.33333333333334 | Topological domain | Cytoplasmic | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 435_447 | 290 | 237.33333333333334 | Topological domain | Cytoplasmic | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 540_757 | 290 | 237.33333333333334 | Topological domain | Cytoplasmic | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 371_379 | 290 | 237.33333333333334 | Topological domain | Cytoplasmic | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 435_447 | 290 | 237.33333333333334 | Topological domain | Cytoplasmic | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 540_757 | 290 | 237.33333333333334 | Topological domain | Cytoplasmic | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 291_309 | 290 | 237.33333333333334 | Transmembrane | Helical%3B Name%3DSegment S1 | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 351_370 | 290 | 237.33333333333334 | Transmembrane | Helical%3B Name%3DSegment S2 | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 380_398 | 290 | 237.33333333333334 | Transmembrane | Helical%3B Name%3DSegment S3 | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 412_434 | 290 | 237.33333333333334 | Transmembrane | Helical%3B Voltage-sensor%3B Name%3DSegment S4 | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 448_469 | 290 | 237.33333333333334 | Transmembrane | Helical%3B Name%3DSegment S5 | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 518_539 | 290 | 237.33333333333334 | Transmembrane | Helical%3B Name%3DSegment S6 | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 291_309 | 290 | 237.33333333333334 | Transmembrane | Helical%3B Name%3DSegment S1 | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 351_370 | 290 | 237.33333333333334 | Transmembrane | Helical%3B Name%3DSegment S2 | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 380_398 | 290 | 237.33333333333334 | Transmembrane | Helical%3B Name%3DSegment S3 | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 412_434 | 290 | 237.33333333333334 | Transmembrane | Helical%3B Voltage-sensor%3B Name%3DSegment S4 | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 448_469 | 290 | 237.33333333333334 | Transmembrane | Helical%3B Name%3DSegment S5 | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 518_539 | 290 | 237.33333333333334 | Transmembrane | Helical%3B Name%3DSegment S6 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TMEM189 | chr20:48770053 | chr19:50827339 | ENST00000371652 | - | 1 | 6 | 186_190 | 40 | 271.0 | Motif | Histidine box-1 |
| Hgene | TMEM189 | chr20:48770053 | chr19:50827339 | ENST00000371652 | - | 1 | 6 | 213_217 | 40 | 271.0 | Motif | Histidine box-2 |
| Hgene | TMEM189 | chr20:48770054 | chr19:50827339 | ENST00000371652 | - | 1 | 6 | 186_190 | 40 | 271.0 | Motif | Histidine box-1 |
| Hgene | TMEM189 | chr20:48770054 | chr19:50827339 | ENST00000371652 | - | 1 | 6 | 213_217 | 40 | 271.0 | Motif | Histidine box-2 |
| Hgene | TMEM189 | chr20:48770053 | chr19:50827339 | ENST00000371652 | - | 1 | 6 | 161_181 | 40 | 271.0 | Transmembrane | Helical |
| Hgene | TMEM189 | chr20:48770053 | chr19:50827339 | ENST00000371652 | - | 1 | 6 | 47_67 | 40 | 271.0 | Transmembrane | Helical |
| Hgene | TMEM189 | chr20:48770053 | chr19:50827339 | ENST00000371652 | - | 1 | 6 | 74_94 | 40 | 271.0 | Transmembrane | Helical |
| Hgene | TMEM189 | chr20:48770054 | chr19:50827339 | ENST00000371652 | - | 1 | 6 | 161_181 | 40 | 271.0 | Transmembrane | Helical |
| Hgene | TMEM189 | chr20:48770054 | chr19:50827339 | ENST00000371652 | - | 1 | 6 | 47_67 | 40 | 271.0 | Transmembrane | Helical |
| Hgene | TMEM189 | chr20:48770054 | chr19:50827339 | ENST00000371652 | - | 1 | 6 | 74_94 | 40 | 271.0 | Transmembrane | Helical |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 229_234 | 290 | 237.33333333333334 | Compositional bias | Note=Poly-Gly | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 31_38 | 290 | 237.33333333333334 | Compositional bias | Note=Poly-Pro | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 39_42 | 290 | 237.33333333333334 | Compositional bias | Note=Poly-Gln | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 81_85 | 290 | 237.33333333333334 | Compositional bias | Note=Poly-Gly | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 229_234 | 290 | 237.33333333333334 | Compositional bias | Note=Poly-Gly | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 31_38 | 290 | 237.33333333333334 | Compositional bias | Note=Poly-Pro | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 39_42 | 290 | 237.33333333333334 | Compositional bias | Note=Poly-Gln | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 81_85 | 290 | 237.33333333333334 | Compositional bias | Note=Poly-Gly | |
| Tgene | KCNC3 | chr20:48770053 | chr19:50827339 | ENST00000477616 | 0 | 5 | 1_290 | 290 | 237.33333333333334 | Topological domain | Cytoplasmic | |
| Tgene | KCNC3 | chr20:48770054 | chr19:50827339 | ENST00000477616 | 0 | 5 | 1_290 | 290 | 237.33333333333334 | Topological domain | Cytoplasmic |
Top |
Fusion Gene Sequence for TMEM189-KCNC3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >91845_91845_1_TMEM189-KCNC3_TMEM189_chr20_48770053_ENST00000371650_KCNC3_chr19_50827339_ENST00000376959_length(transcript)=4631nt_BP=218nt GCTGGGCGGTCATTGGGCGGCGTGATCTCGCCGCGGTTCCGCGGCCCTGCCGCCGCCGCCGCCAGCAGAGCGCACCGGGCCGATCGGGCG AGTGGCCATGGCGGGCGCCGAGAACTGGCCGGGCCAGCAGCTGGAGCTGGACGAGGACGAGGCGTCTTGTTGCCGCTGGGGCGCGCAGCA CGCCGGGGCCCGCGAGCTGGCTGCGCTCTACTCGCCAGTATGTGGCCTTCGCCTCCCTCTTCTTCATCCTCATCTCCATCACCACCTTCT GCCTGGAAACCCATGAGGGCTTCATCCATATTAGCAACAAGACGGTGACCCAGGCCTCCCCGATCCCCGGGGCACCTCCGGAGAACATCA CCAACGTGGAGGTGGAGACGGAGCCCTTCCTGACCTACGTGGAGGGGGTGTGCGTGGTCTGGTTCACCTTCGAGTTCCTCATGCGCATCA CCTTCTGCCCAGACAAGGTGGAGTTTCTTAAAAGCAGCCTCAACATCATCGACTGTGTGGCCATCCTGCCCTTCTATCTCGAGGTGGGCC TCTCGGGCCTCAGCTCCAAGGCCGCCAAAGACGTGCTGGGCTTCCTGCGGGTGGTCCGCTTCGTCCGCATCCTGCGCATCTTCAAGCTGA CCCGGCACTTCGTGGGGCTGCGCGTGCTGGGACACACGCTCCGCGCCAGCACCAACGAGTTCCTGCTGCTCATCATCTTCCTGGCCCTGG GGGTGCTCATCTTCGCCACCATGATTTACTACGCTGAGCGCATTGGCGCCGACCCCGATGACATCCTGGGCTCCAACCACACCTACTTCA AGAACATCCCCATTGGCTTCTGGTGGGCTGTGGTCACCATGACGACCCTGGGCTATGGAGACATGTACCCCAAGACGTGGTCGGGGATGC TGGTCGGGGCGCTGTGTGCCCTGGCGGGGGTGCTGACCATCGCCATGCCTGTGCCCGTCATTGTCAACAACTTTGGCATGTACTATTCGC TGGCCATGGCCAAGCAGAAGCTGCCCAAGAAGAAGAACAAACACATCCCCCGGCCCCCGCAACCGGGCTCGCCCAACTACTGCAAGCCTG ACCCACCCCCGCCACCCCCGCCCCACCCGCACCACGGCAGCGGGGGCATCAGCCCGCCGCCACCCATCACCCCACCCTCCATGGGGGTGA CTGTGGCCGGGGCCTACCCAGCGGGGCCCCACACGCACCCCGGGCTGCTCAGGGGGGGAGCGGGTGGGCTGGGGATCATGGGGCTGCCTC CTCTGCCAGCCCCCGGCGAGCCTTGCCCGTTGGCTCAGGAGGAGGTGATTGAGATCAACCGGGCAGATCCTCGCCCCAATGGGGATCCGG CAGCAGCTGCGCTTGCCCACGAGGACTGCCCAGCCATTGACCAGCCTGCCATGTCCCCGGAAGACAAGAGCCCCATCACGCCTGGAAGCC GTGGCCGCTATAGCCGGGACCGAGCCTGCTTCCTCCTCACCGACTATGCCCCTTCCCCTGATGGCTCCATCCGAAAAGCTCTTGTCACCG CCTGAGACCTCGCGAGACTTTCGGTCCCCCCCGCCCCTTCCCCCCAGGTTACGAGAAATCCCGCAGCCTCAGCAGCATCGCGGGCCTGAG CGGGGTGTCCCTGCGCCTCGCGCCCCTTGCCACCCCCCCTGGCTCTCCCCGGGCCGCCCGCCGCGCTCCCCCGACCCTGCCCTCCATCCT TTAGCGCTCCCCTCCCCCCTGTGGGGGGACTCGGGGGTGACCGGGAAGAAGGTCAAAGGAGCTGGGGGTGGGGGGTGGGGAAAAGGGTTT TTTTAAAAAAAATCAAAAAGTCATTAATAATATGCAACCGAGATGACGATGCCAGCAGACACCCCCGGGCCCCTCACCCCCAACCTGGGC CCCCAGGATGGAGAGAGGGGCCACAGCCCGTCCCCCCAACTCTTCCCTCCCCAAAAAAAGCCTTCTCAGGTCTCCACGAGCCATAGGACA TCCCCCTGCCATCAACTTGTGTAAATAAGTCCAAATTATGCCAGTTACATCTTGGGGCACCTCCCCCCACACACTGCATGCCTTCCCTAA CCTGGAGCCCCCACTCCAAGTCCACCTCAGCAATAAGCCGCCAGGGGCCGCATGCGCGGGTTTGAGGGGCAGGCACTCTGGGAAGGGGGT GGCACCTCCCGGGGGTCGGGCTGGCCTTTAAGGTCTCCAGCCTTCCCATCCTTCACCCCAGGAGGACAACCAACCCTGTGCGTTGATTAG GAGAAAACAAACCAGAAACTAGAAACAGTGTAGGGGAAGGAGGAACAGTTACCCAAGCCCCAGATCGGAGTTGAGCTCAGGTGGCGGGAG GGCGGGGCCGAGTTGAGCTCAGGTGGTGGGAGGGCGGGGCGGGCTTTGGACCTGCTCCCTCAGCCTTTAGGAGAATTCCTCTGGTGAATT TCACCCTCTCATCCGCCCCTTCCCCCAGGGACCTGCTCGCCTCTATTCTTGCTGCATGGACTCAGACCTCCTATCCCAGAATTCCTGGGA TGATCTGGCCCTAGCACACGAAATTCCCCGACTATCTCCCTCCATTCCCAGGACATGAGACCTGCACCCAGAATTCTGAGACTGACCCTG GCACGCCACATCTCCCAATCCCCACACACTCCTGCGACTTAACCTCTGCACACAGAGGCTCCCTGAACCACCCTCCCTCCCCACTCCTGC CACCCCAAACACCCCCACCAAATTCCCTGAACTGCGTCCCAGCACTTCTCAAACCTCCAAGACTTGACCCAGCTCTTTTCAGCTCAAATT CAGCCTTTGGGATGCTCCAAATCCTTCCCACAACTGACATTTCTTGGACACCCCCAAAGCCTCAGGCCTGTTCCGCACCCATATCCCCAA AGCCCTAACAGACTTGTCCAGCCCAGGTTCCCTTGATGCTAGAACTTCCAAGATAGGCGCAACCTGTCTGCAATTCCAGGGAACCAGACC CTCCCCAAGCACCCTCTTTGTCTTACGCCTAACCCTGAGTCTCTTCCCTGAGATGGTGCCCCAAAGGTACCCTCTTCACAGACACCAGTG TTTCCCAGAGGGTTGTATTTGTACCTTTGGTGGTGTGCTAAGGTTTGAGGCAGTATGAGGACAAACACTTGTTTTAAAAGTTTTGTCTCT AATACGCATTTTGTACAGAAGCCGATAAGTGCAGGCATCGCTGCTTGGCTAGGACACGGTTTATTTAGGTTAAGAGTGTTTCCATTTAAA GTAGTCCACAGATGATCACAGAGGCTGTTCCCGAAGGGAGGAACACTGGAGTATCAGAAGATTGGGAACCGACAACACCCAGCTCGGCTG GGATCCCAGCCCCCCTTCCCCAGCGGTCCTCACCGCGTCACGCTCGCGGGTGGAAAATCATTTCCCACCTCCTATCCTGGCTCAAGGATG CGCTACCTCCCCCAAGCCCAGAGACCACACCGGTCCCAGACTCTTTAGCGGACCCCCCTTTTGGAGCCGGGGTCCCACGGAATTAGCCAC CTCCCTCCCTCTGCTCCCACGGCCTCAGGAACCCCCCACCCGAGGGTGGATGGGGGGCGTCACTGAGCACGATTCTCGATGCAACGATTC CTATGCAAGGGGCATTTTGAGTCCCCCCCATCCTTCCCTCGGACCCTAAACCCTGGTGAAGCAGGGGTGAGGGGTGGGGCGGGTTTTGGT GGGGGCGGGGCAAAGGGCTAGGGGCTCCAGACACCAGGGTACGGGGTGGGGACTGATTATATTGCCAAAGGGTTCAACTTCTTTAACAAG CCCCCCCGTTTCCCCTGACCTTCACGAAAGCCGAAGGAGGCGGGGAAAGGGGGTGAGGGTCTTTTCCAAAGGGTACTGACCTCTTCCCAA CGTCTCCCCCTGCTCGCCAGTCCGCCACACGTACCCAGCTTTTGAGTTCAGCTTTTCAAAATAACCACAATCATGATAAACTTCTACAAA ACGTGATTCTCCTCCCCTCCCACCCCATCCCCCAAGTCAATAGTGTGGGATTCGGGGAGGGAGAGAGCGAGCTAAAGGGACTCTTTCCAA GTCCGGCTCCCCCTTTTCCCCCCGGCCGCCAGGGTGCCTGCACCTACACGCATGCGCTGCATGACGCGCCCCCCACACGCATGTCGCACC CCTCCTGCGCTCCGGGAACGCACGGACACGGGCCAGGGGGCGGGGCGATTGGGGAGGAATGAATGGCGGGGGGTCTTCCTGAGCTCCGCG GCTCACCCTCCCCAACACACACACACACACACACAGAGCAATAAGTTTCTCTCACTCAAATGTGGGCGGGGCGGGCCTAGCCTGTCGCTG GTGGGGGGAGTGGTGAGGGGGCGCTCTCAGGGATGGGGGCGGGGTTCGGAGACAGTGTGGGGAGGGGAGGTCTGCAAATCGTCCAACTCT GGTGCTAATGGCGGGTCTTCTCAGCCCACCCGCAGGGCAGGGAGGGAGGGGTCGGCGTGGCCCCTTCCCCAAGCCTCCCCCACGCCCACC CTGGGTGCATGAACCGCCCAATGCAGAAGCTGCCGCATGTCACCCCCCTCTCCCCAAAGAAAAAGTGTCATGCCCCCTTCCCACCCACCC >91845_91845_1_TMEM189-KCNC3_TMEM189_chr20_48770053_ENST00000371650_KCNC3_chr19_50827339_ENST00000376959_length(amino acids)=525AA_BP=1 MGGRGGGDRKSREVSGGDKSFSDGAIRGRGIVGEEEAGSVPAIAATASRRDGALVFRGHGRLVNGWAVLVGKRSCCRIPIGARICPVDLN HLLLSQRARLAGGWQRRQPHDPQPTRSPPEQPGVRVGPRWVGPGHSHPHGGWGDGWRRADAPAAVVRVGRGWRGWVRLAVVGRARLRGPG DVFVLLLGQLLLGHGQRIVHAKVVDNDGHRHGDGQHPRQGTQRPDQHPRPRLGVHVSIAQGRHGDHSPPEANGDVLEVGVVGAQDVIGVG ANALSVVNHGGEDEHPQGQEDDEQQELVGAGAERVSQHAQPHEVPGQLEDAQDADEADHPQEAQHVFGGLGAEAREAHLEIEGQDGHTVD DVEAAFKKLHLVWAEGDAHEELEGEPDHAHPLHVGQEGLRLHLHVGDVLRRCPGDRGGLGHRLVANMDEALMGFQAEGGDGDEDEEEGGE -------------------------------------------------------------- >91845_91845_2_TMEM189-KCNC3_TMEM189_chr20_48770053_ENST00000371652_KCNC3_chr19_50827339_ENST00000376959_length(transcript)=4631nt_BP=218nt GCTGGGCGGTCATTGGGCGGCGTGATCTCGCCGCGGTTCCGCGGCCCTGCCGCCGCCGCCGCCAGCAGAGCGCACCGGGCCGATCGGGCG AGTGGCCATGGCGGGCGCCGAGAACTGGCCGGGCCAGCAGCTGGAGCTGGACGAGGACGAGGCGTCTTGTTGCCGCTGGGGCGCGCAGCA CGCCGGGGCCCGCGAGCTGGCTGCGCTCTACTCGCCAGTATGTGGCCTTCGCCTCCCTCTTCTTCATCCTCATCTCCATCACCACCTTCT GCCTGGAAACCCATGAGGGCTTCATCCATATTAGCAACAAGACGGTGACCCAGGCCTCCCCGATCCCCGGGGCACCTCCGGAGAACATCA CCAACGTGGAGGTGGAGACGGAGCCCTTCCTGACCTACGTGGAGGGGGTGTGCGTGGTCTGGTTCACCTTCGAGTTCCTCATGCGCATCA CCTTCTGCCCAGACAAGGTGGAGTTTCTTAAAAGCAGCCTCAACATCATCGACTGTGTGGCCATCCTGCCCTTCTATCTCGAGGTGGGCC TCTCGGGCCTCAGCTCCAAGGCCGCCAAAGACGTGCTGGGCTTCCTGCGGGTGGTCCGCTTCGTCCGCATCCTGCGCATCTTCAAGCTGA CCCGGCACTTCGTGGGGCTGCGCGTGCTGGGACACACGCTCCGCGCCAGCACCAACGAGTTCCTGCTGCTCATCATCTTCCTGGCCCTGG GGGTGCTCATCTTCGCCACCATGATTTACTACGCTGAGCGCATTGGCGCCGACCCCGATGACATCCTGGGCTCCAACCACACCTACTTCA AGAACATCCCCATTGGCTTCTGGTGGGCTGTGGTCACCATGACGACCCTGGGCTATGGAGACATGTACCCCAAGACGTGGTCGGGGATGC TGGTCGGGGCGCTGTGTGCCCTGGCGGGGGTGCTGACCATCGCCATGCCTGTGCCCGTCATTGTCAACAACTTTGGCATGTACTATTCGC TGGCCATGGCCAAGCAGAAGCTGCCCAAGAAGAAGAACAAACACATCCCCCGGCCCCCGCAACCGGGCTCGCCCAACTACTGCAAGCCTG ACCCACCCCCGCCACCCCCGCCCCACCCGCACCACGGCAGCGGGGGCATCAGCCCGCCGCCACCCATCACCCCACCCTCCATGGGGGTGA CTGTGGCCGGGGCCTACCCAGCGGGGCCCCACACGCACCCCGGGCTGCTCAGGGGGGGAGCGGGTGGGCTGGGGATCATGGGGCTGCCTC CTCTGCCAGCCCCCGGCGAGCCTTGCCCGTTGGCTCAGGAGGAGGTGATTGAGATCAACCGGGCAGATCCTCGCCCCAATGGGGATCCGG CAGCAGCTGCGCTTGCCCACGAGGACTGCCCAGCCATTGACCAGCCTGCCATGTCCCCGGAAGACAAGAGCCCCATCACGCCTGGAAGCC GTGGCCGCTATAGCCGGGACCGAGCCTGCTTCCTCCTCACCGACTATGCCCCTTCCCCTGATGGCTCCATCCGAAAAGCTCTTGTCACCG CCTGAGACCTCGCGAGACTTTCGGTCCCCCCCGCCCCTTCCCCCCAGGTTACGAGAAATCCCGCAGCCTCAGCAGCATCGCGGGCCTGAG CGGGGTGTCCCTGCGCCTCGCGCCCCTTGCCACCCCCCCTGGCTCTCCCCGGGCCGCCCGCCGCGCTCCCCCGACCCTGCCCTCCATCCT TTAGCGCTCCCCTCCCCCCTGTGGGGGGACTCGGGGGTGACCGGGAAGAAGGTCAAAGGAGCTGGGGGTGGGGGGTGGGGAAAAGGGTTT TTTTAAAAAAAATCAAAAAGTCATTAATAATATGCAACCGAGATGACGATGCCAGCAGACACCCCCGGGCCCCTCACCCCCAACCTGGGC CCCCAGGATGGAGAGAGGGGCCACAGCCCGTCCCCCCAACTCTTCCCTCCCCAAAAAAAGCCTTCTCAGGTCTCCACGAGCCATAGGACA TCCCCCTGCCATCAACTTGTGTAAATAAGTCCAAATTATGCCAGTTACATCTTGGGGCACCTCCCCCCACACACTGCATGCCTTCCCTAA CCTGGAGCCCCCACTCCAAGTCCACCTCAGCAATAAGCCGCCAGGGGCCGCATGCGCGGGTTTGAGGGGCAGGCACTCTGGGAAGGGGGT GGCACCTCCCGGGGGTCGGGCTGGCCTTTAAGGTCTCCAGCCTTCCCATCCTTCACCCCAGGAGGACAACCAACCCTGTGCGTTGATTAG GAGAAAACAAACCAGAAACTAGAAACAGTGTAGGGGAAGGAGGAACAGTTACCCAAGCCCCAGATCGGAGTTGAGCTCAGGTGGCGGGAG GGCGGGGCCGAGTTGAGCTCAGGTGGTGGGAGGGCGGGGCGGGCTTTGGACCTGCTCCCTCAGCCTTTAGGAGAATTCCTCTGGTGAATT TCACCCTCTCATCCGCCCCTTCCCCCAGGGACCTGCTCGCCTCTATTCTTGCTGCATGGACTCAGACCTCCTATCCCAGAATTCCTGGGA TGATCTGGCCCTAGCACACGAAATTCCCCGACTATCTCCCTCCATTCCCAGGACATGAGACCTGCACCCAGAATTCTGAGACTGACCCTG GCACGCCACATCTCCCAATCCCCACACACTCCTGCGACTTAACCTCTGCACACAGAGGCTCCCTGAACCACCCTCCCTCCCCACTCCTGC CACCCCAAACACCCCCACCAAATTCCCTGAACTGCGTCCCAGCACTTCTCAAACCTCCAAGACTTGACCCAGCTCTTTTCAGCTCAAATT CAGCCTTTGGGATGCTCCAAATCCTTCCCACAACTGACATTTCTTGGACACCCCCAAAGCCTCAGGCCTGTTCCGCACCCATATCCCCAA AGCCCTAACAGACTTGTCCAGCCCAGGTTCCCTTGATGCTAGAACTTCCAAGATAGGCGCAACCTGTCTGCAATTCCAGGGAACCAGACC CTCCCCAAGCACCCTCTTTGTCTTACGCCTAACCCTGAGTCTCTTCCCTGAGATGGTGCCCCAAAGGTACCCTCTTCACAGACACCAGTG TTTCCCAGAGGGTTGTATTTGTACCTTTGGTGGTGTGCTAAGGTTTGAGGCAGTATGAGGACAAACACTTGTTTTAAAAGTTTTGTCTCT AATACGCATTTTGTACAGAAGCCGATAAGTGCAGGCATCGCTGCTTGGCTAGGACACGGTTTATTTAGGTTAAGAGTGTTTCCATTTAAA GTAGTCCACAGATGATCACAGAGGCTGTTCCCGAAGGGAGGAACACTGGAGTATCAGAAGATTGGGAACCGACAACACCCAGCTCGGCTG GGATCCCAGCCCCCCTTCCCCAGCGGTCCTCACCGCGTCACGCTCGCGGGTGGAAAATCATTTCCCACCTCCTATCCTGGCTCAAGGATG CGCTACCTCCCCCAAGCCCAGAGACCACACCGGTCCCAGACTCTTTAGCGGACCCCCCTTTTGGAGCCGGGGTCCCACGGAATTAGCCAC CTCCCTCCCTCTGCTCCCACGGCCTCAGGAACCCCCCACCCGAGGGTGGATGGGGGGCGTCACTGAGCACGATTCTCGATGCAACGATTC CTATGCAAGGGGCATTTTGAGTCCCCCCCATCCTTCCCTCGGACCCTAAACCCTGGTGAAGCAGGGGTGAGGGGTGGGGCGGGTTTTGGT GGGGGCGGGGCAAAGGGCTAGGGGCTCCAGACACCAGGGTACGGGGTGGGGACTGATTATATTGCCAAAGGGTTCAACTTCTTTAACAAG CCCCCCCGTTTCCCCTGACCTTCACGAAAGCCGAAGGAGGCGGGGAAAGGGGGTGAGGGTCTTTTCCAAAGGGTACTGACCTCTTCCCAA CGTCTCCCCCTGCTCGCCAGTCCGCCACACGTACCCAGCTTTTGAGTTCAGCTTTTCAAAATAACCACAATCATGATAAACTTCTACAAA ACGTGATTCTCCTCCCCTCCCACCCCATCCCCCAAGTCAATAGTGTGGGATTCGGGGAGGGAGAGAGCGAGCTAAAGGGACTCTTTCCAA GTCCGGCTCCCCCTTTTCCCCCCGGCCGCCAGGGTGCCTGCACCTACACGCATGCGCTGCATGACGCGCCCCCCACACGCATGTCGCACC CCTCCTGCGCTCCGGGAACGCACGGACACGGGCCAGGGGGCGGGGCGATTGGGGAGGAATGAATGGCGGGGGGTCTTCCTGAGCTCCGCG GCTCACCCTCCCCAACACACACACACACACACACAGAGCAATAAGTTTCTCTCACTCAAATGTGGGCGGGGCGGGCCTAGCCTGTCGCTG GTGGGGGGAGTGGTGAGGGGGCGCTCTCAGGGATGGGGGCGGGGTTCGGAGACAGTGTGGGGAGGGGAGGTCTGCAAATCGTCCAACTCT GGTGCTAATGGCGGGTCTTCTCAGCCCACCCGCAGGGCAGGGAGGGAGGGGTCGGCGTGGCCCCTTCCCCAAGCCTCCCCCACGCCCACC CTGGGTGCATGAACCGCCCAATGCAGAAGCTGCCGCATGTCACCCCCCTCTCCCCAAAGAAAAAGTGTCATGCCCCCTTCCCACCCACCC >91845_91845_2_TMEM189-KCNC3_TMEM189_chr20_48770053_ENST00000371652_KCNC3_chr19_50827339_ENST00000376959_length(amino acids)=525AA_BP=1 MGGRGGGDRKSREVSGGDKSFSDGAIRGRGIVGEEEAGSVPAIAATASRRDGALVFRGHGRLVNGWAVLVGKRSCCRIPIGARICPVDLN HLLLSQRARLAGGWQRRQPHDPQPTRSPPEQPGVRVGPRWVGPGHSHPHGGWGDGWRRADAPAAVVRVGRGWRGWVRLAVVGRARLRGPG DVFVLLLGQLLLGHGQRIVHAKVVDNDGHRHGDGQHPRQGTQRPDQHPRPRLGVHVSIAQGRHGDHSPPEANGDVLEVGVVGAQDVIGVG ANALSVVNHGGEDEHPQGQEDDEQQELVGAGAERVSQHAQPHEVPGQLEDAQDADEADHPQEAQHVFGGLGAEAREAHLEIEGQDGHTVD DVEAAFKKLHLVWAEGDAHEELEGEPDHAHPLHVGQEGLRLHLHVGDVLRRCPGDRGGLGHRLVANMDEALMGFQAEGGDGDEDEEEGGE -------------------------------------------------------------- >91845_91845_3_TMEM189-KCNC3_TMEM189_chr20_48770053_ENST00000557021_KCNC3_chr19_50827339_ENST00000376959_length(transcript)=4695nt_BP=282nt AGCCCCGATTGGCTGTGACGCGCGGCCGGGCGAGGACCCCGCCCGCGCCGCCGCCGCGCCCGGCGCTGGGCGGTCATTGGGCGGCGTGAT CTCGCCGCGGTTCCGCGGCCCTGCCGCCGCCGCCGCCAGCAGAGCGCACCGGGCCGATCGGGCGAGTGGCCATGGCGGGCGCCGAGAACT GGCCGGGCCAGCAGCTGGAGCTGGACGAGGACGAGGCGTCTTGTTGCCGCTGGGGCGCGCAGCACGCCGGGGCCCGCGAGCTGGCTGCGC TCTACTCGCCAGTATGTGGCCTTCGCCTCCCTCTTCTTCATCCTCATCTCCATCACCACCTTCTGCCTGGAAACCCATGAGGGCTTCATC CATATTAGCAACAAGACGGTGACCCAGGCCTCCCCGATCCCCGGGGCACCTCCGGAGAACATCACCAACGTGGAGGTGGAGACGGAGCCC TTCCTGACCTACGTGGAGGGGGTGTGCGTGGTCTGGTTCACCTTCGAGTTCCTCATGCGCATCACCTTCTGCCCAGACAAGGTGGAGTTT CTTAAAAGCAGCCTCAACATCATCGACTGTGTGGCCATCCTGCCCTTCTATCTCGAGGTGGGCCTCTCGGGCCTCAGCTCCAAGGCCGCC AAAGACGTGCTGGGCTTCCTGCGGGTGGTCCGCTTCGTCCGCATCCTGCGCATCTTCAAGCTGACCCGGCACTTCGTGGGGCTGCGCGTG CTGGGACACACGCTCCGCGCCAGCACCAACGAGTTCCTGCTGCTCATCATCTTCCTGGCCCTGGGGGTGCTCATCTTCGCCACCATGATT TACTACGCTGAGCGCATTGGCGCCGACCCCGATGACATCCTGGGCTCCAACCACACCTACTTCAAGAACATCCCCATTGGCTTCTGGTGG GCTGTGGTCACCATGACGACCCTGGGCTATGGAGACATGTACCCCAAGACGTGGTCGGGGATGCTGGTCGGGGCGCTGTGTGCCCTGGCG GGGGTGCTGACCATCGCCATGCCTGTGCCCGTCATTGTCAACAACTTTGGCATGTACTATTCGCTGGCCATGGCCAAGCAGAAGCTGCCC AAGAAGAAGAACAAACACATCCCCCGGCCCCCGCAACCGGGCTCGCCCAACTACTGCAAGCCTGACCCACCCCCGCCACCCCCGCCCCAC CCGCACCACGGCAGCGGGGGCATCAGCCCGCCGCCACCCATCACCCCACCCTCCATGGGGGTGACTGTGGCCGGGGCCTACCCAGCGGGG CCCCACACGCACCCCGGGCTGCTCAGGGGGGGAGCGGGTGGGCTGGGGATCATGGGGCTGCCTCCTCTGCCAGCCCCCGGCGAGCCTTGC CCGTTGGCTCAGGAGGAGGTGATTGAGATCAACCGGGCAGATCCTCGCCCCAATGGGGATCCGGCAGCAGCTGCGCTTGCCCACGAGGAC TGCCCAGCCATTGACCAGCCTGCCATGTCCCCGGAAGACAAGAGCCCCATCACGCCTGGAAGCCGTGGCCGCTATAGCCGGGACCGAGCC TGCTTCCTCCTCACCGACTATGCCCCTTCCCCTGATGGCTCCATCCGAAAAGCTCTTGTCACCGCCTGAGACCTCGCGAGACTTTCGGTC CCCCCCGCCCCTTCCCCCCAGGTTACGAGAAATCCCGCAGCCTCAGCAGCATCGCGGGCCTGAGCGGGGTGTCCCTGCGCCTCGCGCCCC TTGCCACCCCCCCTGGCTCTCCCCGGGCCGCCCGCCGCGCTCCCCCGACCCTGCCCTCCATCCTTTAGCGCTCCCCTCCCCCCTGTGGGG GGACTCGGGGGTGACCGGGAAGAAGGTCAAAGGAGCTGGGGGTGGGGGGTGGGGAAAAGGGTTTTTTTAAAAAAAATCAAAAAGTCATTA ATAATATGCAACCGAGATGACGATGCCAGCAGACACCCCCGGGCCCCTCACCCCCAACCTGGGCCCCCAGGATGGAGAGAGGGGCCACAG CCCGTCCCCCCAACTCTTCCCTCCCCAAAAAAAGCCTTCTCAGGTCTCCACGAGCCATAGGACATCCCCCTGCCATCAACTTGTGTAAAT AAGTCCAAATTATGCCAGTTACATCTTGGGGCACCTCCCCCCACACACTGCATGCCTTCCCTAACCTGGAGCCCCCACTCCAAGTCCACC TCAGCAATAAGCCGCCAGGGGCCGCATGCGCGGGTTTGAGGGGCAGGCACTCTGGGAAGGGGGTGGCACCTCCCGGGGGTCGGGCTGGCC TTTAAGGTCTCCAGCCTTCCCATCCTTCACCCCAGGAGGACAACCAACCCTGTGCGTTGATTAGGAGAAAACAAACCAGAAACTAGAAAC AGTGTAGGGGAAGGAGGAACAGTTACCCAAGCCCCAGATCGGAGTTGAGCTCAGGTGGCGGGAGGGCGGGGCCGAGTTGAGCTCAGGTGG TGGGAGGGCGGGGCGGGCTTTGGACCTGCTCCCTCAGCCTTTAGGAGAATTCCTCTGGTGAATTTCACCCTCTCATCCGCCCCTTCCCCC AGGGACCTGCTCGCCTCTATTCTTGCTGCATGGACTCAGACCTCCTATCCCAGAATTCCTGGGATGATCTGGCCCTAGCACACGAAATTC CCCGACTATCTCCCTCCATTCCCAGGACATGAGACCTGCACCCAGAATTCTGAGACTGACCCTGGCACGCCACATCTCCCAATCCCCACA CACTCCTGCGACTTAACCTCTGCACACAGAGGCTCCCTGAACCACCCTCCCTCCCCACTCCTGCCACCCCAAACACCCCCACCAAATTCC CTGAACTGCGTCCCAGCACTTCTCAAACCTCCAAGACTTGACCCAGCTCTTTTCAGCTCAAATTCAGCCTTTGGGATGCTCCAAATCCTT CCCACAACTGACATTTCTTGGACACCCCCAAAGCCTCAGGCCTGTTCCGCACCCATATCCCCAAAGCCCTAACAGACTTGTCCAGCCCAG GTTCCCTTGATGCTAGAACTTCCAAGATAGGCGCAACCTGTCTGCAATTCCAGGGAACCAGACCCTCCCCAAGCACCCTCTTTGTCTTAC GCCTAACCCTGAGTCTCTTCCCTGAGATGGTGCCCCAAAGGTACCCTCTTCACAGACACCAGTGTTTCCCAGAGGGTTGTATTTGTACCT TTGGTGGTGTGCTAAGGTTTGAGGCAGTATGAGGACAAACACTTGTTTTAAAAGTTTTGTCTCTAATACGCATTTTGTACAGAAGCCGAT AAGTGCAGGCATCGCTGCTTGGCTAGGACACGGTTTATTTAGGTTAAGAGTGTTTCCATTTAAAGTAGTCCACAGATGATCACAGAGGCT GTTCCCGAAGGGAGGAACACTGGAGTATCAGAAGATTGGGAACCGACAACACCCAGCTCGGCTGGGATCCCAGCCCCCCTTCCCCAGCGG TCCTCACCGCGTCACGCTCGCGGGTGGAAAATCATTTCCCACCTCCTATCCTGGCTCAAGGATGCGCTACCTCCCCCAAGCCCAGAGACC ACACCGGTCCCAGACTCTTTAGCGGACCCCCCTTTTGGAGCCGGGGTCCCACGGAATTAGCCACCTCCCTCCCTCTGCTCCCACGGCCTC AGGAACCCCCCACCCGAGGGTGGATGGGGGGCGTCACTGAGCACGATTCTCGATGCAACGATTCCTATGCAAGGGGCATTTTGAGTCCCC CCCATCCTTCCCTCGGACCCTAAACCCTGGTGAAGCAGGGGTGAGGGGTGGGGCGGGTTTTGGTGGGGGCGGGGCAAAGGGCTAGGGGCT CCAGACACCAGGGTACGGGGTGGGGACTGATTATATTGCCAAAGGGTTCAACTTCTTTAACAAGCCCCCCCGTTTCCCCTGACCTTCACG AAAGCCGAAGGAGGCGGGGAAAGGGGGTGAGGGTCTTTTCCAAAGGGTACTGACCTCTTCCCAACGTCTCCCCCTGCTCGCCAGTCCGCC ACACGTACCCAGCTTTTGAGTTCAGCTTTTCAAAATAACCACAATCATGATAAACTTCTACAAAACGTGATTCTCCTCCCCTCCCACCCC ATCCCCCAAGTCAATAGTGTGGGATTCGGGGAGGGAGAGAGCGAGCTAAAGGGACTCTTTCCAAGTCCGGCTCCCCCTTTTCCCCCCGGC CGCCAGGGTGCCTGCACCTACACGCATGCGCTGCATGACGCGCCCCCCACACGCATGTCGCACCCCTCCTGCGCTCCGGGAACGCACGGA CACGGGCCAGGGGGCGGGGCGATTGGGGAGGAATGAATGGCGGGGGGTCTTCCTGAGCTCCGCGGCTCACCCTCCCCAACACACACACAC ACACACACAGAGCAATAAGTTTCTCTCACTCAAATGTGGGCGGGGCGGGCCTAGCCTGTCGCTGGTGGGGGGAGTGGTGAGGGGGCGCTC TCAGGGATGGGGGCGGGGTTCGGAGACAGTGTGGGGAGGGGAGGTCTGCAAATCGTCCAACTCTGGTGCTAATGGCGGGTCTTCTCAGCC CACCCGCAGGGCAGGGAGGGAGGGGTCGGCGTGGCCCCTTCCCCAAGCCTCCCCCACGCCCACCCTGGGTGCATGAACCGCCCAATGCAG AAGCTGCCGCATGTCACCCCCCTCTCCCCAAAGAAAAAGTGTCATGCCCCCTTCCCACCCACCCTCACTCCCCACCAAAATAAACGTTTC >91845_91845_3_TMEM189-KCNC3_TMEM189_chr20_48770053_ENST00000557021_KCNC3_chr19_50827339_ENST00000376959_length(amino acids)=547AA_BP=1 MGGRGGGDRKSREVSGGDKSFSDGAIRGRGIVGEEEAGSVPAIAATASRRDGALVFRGHGRLVNGWAVLVGKRSCCRIPIGARICPVDLN HLLLSQRARLAGGWQRRQPHDPQPTRSPPEQPGVRVGPRWVGPGHSHPHGGWGDGWRRADAPAAVVRVGRGWRGWVRLAVVGRARLRGPG DVFVLLLGQLLLGHGQRIVHAKVVDNDGHRHGDGQHPRQGTQRPDQHPRPRLGVHVSIAQGRHGDHSPPEANGDVLEVGVVGAQDVIGVG ANALSVVNHGGEDEHPQGQEDDEQQELVGAGAERVSQHAQPHEVPGQLEDAQDADEADHPQEAQHVFGGLGAEAREAHLEIEGQDGHTVD DVEAAFKKLHLVWAEGDAHEELEGEPDHAHPLHVGQEGLRLHLHVGDVLRRCPGDRGGLGHRLVANMDEALMGFQAEGGDGDEDEEEGGE GHILASRAQPARGPRRAARPSGNKTPRPRPAPAAGPASSRRPPWPLARSARCALLAAAAAGPRNRGEITPPNDRPAPGAAAARAGSSPGR -------------------------------------------------------------- >91845_91845_4_TMEM189-KCNC3_TMEM189_chr20_48770054_ENST00000371650_KCNC3_chr19_50827339_ENST00000376959_length(transcript)=4631nt_BP=218nt GCTGGGCGGTCATTGGGCGGCGTGATCTCGCCGCGGTTCCGCGGCCCTGCCGCCGCCGCCGCCAGCAGAGCGCACCGGGCCGATCGGGCG AGTGGCCATGGCGGGCGCCGAGAACTGGCCGGGCCAGCAGCTGGAGCTGGACGAGGACGAGGCGTCTTGTTGCCGCTGGGGCGCGCAGCA CGCCGGGGCCCGCGAGCTGGCTGCGCTCTACTCGCCAGTATGTGGCCTTCGCCTCCCTCTTCTTCATCCTCATCTCCATCACCACCTTCT GCCTGGAAACCCATGAGGGCTTCATCCATATTAGCAACAAGACGGTGACCCAGGCCTCCCCGATCCCCGGGGCACCTCCGGAGAACATCA CCAACGTGGAGGTGGAGACGGAGCCCTTCCTGACCTACGTGGAGGGGGTGTGCGTGGTCTGGTTCACCTTCGAGTTCCTCATGCGCATCA CCTTCTGCCCAGACAAGGTGGAGTTTCTTAAAAGCAGCCTCAACATCATCGACTGTGTGGCCATCCTGCCCTTCTATCTCGAGGTGGGCC TCTCGGGCCTCAGCTCCAAGGCCGCCAAAGACGTGCTGGGCTTCCTGCGGGTGGTCCGCTTCGTCCGCATCCTGCGCATCTTCAAGCTGA CCCGGCACTTCGTGGGGCTGCGCGTGCTGGGACACACGCTCCGCGCCAGCACCAACGAGTTCCTGCTGCTCATCATCTTCCTGGCCCTGG GGGTGCTCATCTTCGCCACCATGATTTACTACGCTGAGCGCATTGGCGCCGACCCCGATGACATCCTGGGCTCCAACCACACCTACTTCA AGAACATCCCCATTGGCTTCTGGTGGGCTGTGGTCACCATGACGACCCTGGGCTATGGAGACATGTACCCCAAGACGTGGTCGGGGATGC TGGTCGGGGCGCTGTGTGCCCTGGCGGGGGTGCTGACCATCGCCATGCCTGTGCCCGTCATTGTCAACAACTTTGGCATGTACTATTCGC TGGCCATGGCCAAGCAGAAGCTGCCCAAGAAGAAGAACAAACACATCCCCCGGCCCCCGCAACCGGGCTCGCCCAACTACTGCAAGCCTG ACCCACCCCCGCCACCCCCGCCCCACCCGCACCACGGCAGCGGGGGCATCAGCCCGCCGCCACCCATCACCCCACCCTCCATGGGGGTGA CTGTGGCCGGGGCCTACCCAGCGGGGCCCCACACGCACCCCGGGCTGCTCAGGGGGGGAGCGGGTGGGCTGGGGATCATGGGGCTGCCTC CTCTGCCAGCCCCCGGCGAGCCTTGCCCGTTGGCTCAGGAGGAGGTGATTGAGATCAACCGGGCAGATCCTCGCCCCAATGGGGATCCGG CAGCAGCTGCGCTTGCCCACGAGGACTGCCCAGCCATTGACCAGCCTGCCATGTCCCCGGAAGACAAGAGCCCCATCACGCCTGGAAGCC GTGGCCGCTATAGCCGGGACCGAGCCTGCTTCCTCCTCACCGACTATGCCCCTTCCCCTGATGGCTCCATCCGAAAAGCTCTTGTCACCG CCTGAGACCTCGCGAGACTTTCGGTCCCCCCCGCCCCTTCCCCCCAGGTTACGAGAAATCCCGCAGCCTCAGCAGCATCGCGGGCCTGAG CGGGGTGTCCCTGCGCCTCGCGCCCCTTGCCACCCCCCCTGGCTCTCCCCGGGCCGCCCGCCGCGCTCCCCCGACCCTGCCCTCCATCCT TTAGCGCTCCCCTCCCCCCTGTGGGGGGACTCGGGGGTGACCGGGAAGAAGGTCAAAGGAGCTGGGGGTGGGGGGTGGGGAAAAGGGTTT TTTTAAAAAAAATCAAAAAGTCATTAATAATATGCAACCGAGATGACGATGCCAGCAGACACCCCCGGGCCCCTCACCCCCAACCTGGGC CCCCAGGATGGAGAGAGGGGCCACAGCCCGTCCCCCCAACTCTTCCCTCCCCAAAAAAAGCCTTCTCAGGTCTCCACGAGCCATAGGACA TCCCCCTGCCATCAACTTGTGTAAATAAGTCCAAATTATGCCAGTTACATCTTGGGGCACCTCCCCCCACACACTGCATGCCTTCCCTAA CCTGGAGCCCCCACTCCAAGTCCACCTCAGCAATAAGCCGCCAGGGGCCGCATGCGCGGGTTTGAGGGGCAGGCACTCTGGGAAGGGGGT GGCACCTCCCGGGGGTCGGGCTGGCCTTTAAGGTCTCCAGCCTTCCCATCCTTCACCCCAGGAGGACAACCAACCCTGTGCGTTGATTAG GAGAAAACAAACCAGAAACTAGAAACAGTGTAGGGGAAGGAGGAACAGTTACCCAAGCCCCAGATCGGAGTTGAGCTCAGGTGGCGGGAG GGCGGGGCCGAGTTGAGCTCAGGTGGTGGGAGGGCGGGGCGGGCTTTGGACCTGCTCCCTCAGCCTTTAGGAGAATTCCTCTGGTGAATT TCACCCTCTCATCCGCCCCTTCCCCCAGGGACCTGCTCGCCTCTATTCTTGCTGCATGGACTCAGACCTCCTATCCCAGAATTCCTGGGA TGATCTGGCCCTAGCACACGAAATTCCCCGACTATCTCCCTCCATTCCCAGGACATGAGACCTGCACCCAGAATTCTGAGACTGACCCTG GCACGCCACATCTCCCAATCCCCACACACTCCTGCGACTTAACCTCTGCACACAGAGGCTCCCTGAACCACCCTCCCTCCCCACTCCTGC CACCCCAAACACCCCCACCAAATTCCCTGAACTGCGTCCCAGCACTTCTCAAACCTCCAAGACTTGACCCAGCTCTTTTCAGCTCAAATT CAGCCTTTGGGATGCTCCAAATCCTTCCCACAACTGACATTTCTTGGACACCCCCAAAGCCTCAGGCCTGTTCCGCACCCATATCCCCAA AGCCCTAACAGACTTGTCCAGCCCAGGTTCCCTTGATGCTAGAACTTCCAAGATAGGCGCAACCTGTCTGCAATTCCAGGGAACCAGACC CTCCCCAAGCACCCTCTTTGTCTTACGCCTAACCCTGAGTCTCTTCCCTGAGATGGTGCCCCAAAGGTACCCTCTTCACAGACACCAGTG TTTCCCAGAGGGTTGTATTTGTACCTTTGGTGGTGTGCTAAGGTTTGAGGCAGTATGAGGACAAACACTTGTTTTAAAAGTTTTGTCTCT AATACGCATTTTGTACAGAAGCCGATAAGTGCAGGCATCGCTGCTTGGCTAGGACACGGTTTATTTAGGTTAAGAGTGTTTCCATTTAAA GTAGTCCACAGATGATCACAGAGGCTGTTCCCGAAGGGAGGAACACTGGAGTATCAGAAGATTGGGAACCGACAACACCCAGCTCGGCTG GGATCCCAGCCCCCCTTCCCCAGCGGTCCTCACCGCGTCACGCTCGCGGGTGGAAAATCATTTCCCACCTCCTATCCTGGCTCAAGGATG CGCTACCTCCCCCAAGCCCAGAGACCACACCGGTCCCAGACTCTTTAGCGGACCCCCCTTTTGGAGCCGGGGTCCCACGGAATTAGCCAC CTCCCTCCCTCTGCTCCCACGGCCTCAGGAACCCCCCACCCGAGGGTGGATGGGGGGCGTCACTGAGCACGATTCTCGATGCAACGATTC CTATGCAAGGGGCATTTTGAGTCCCCCCCATCCTTCCCTCGGACCCTAAACCCTGGTGAAGCAGGGGTGAGGGGTGGGGCGGGTTTTGGT GGGGGCGGGGCAAAGGGCTAGGGGCTCCAGACACCAGGGTACGGGGTGGGGACTGATTATATTGCCAAAGGGTTCAACTTCTTTAACAAG CCCCCCCGTTTCCCCTGACCTTCACGAAAGCCGAAGGAGGCGGGGAAAGGGGGTGAGGGTCTTTTCCAAAGGGTACTGACCTCTTCCCAA CGTCTCCCCCTGCTCGCCAGTCCGCCACACGTACCCAGCTTTTGAGTTCAGCTTTTCAAAATAACCACAATCATGATAAACTTCTACAAA ACGTGATTCTCCTCCCCTCCCACCCCATCCCCCAAGTCAATAGTGTGGGATTCGGGGAGGGAGAGAGCGAGCTAAAGGGACTCTTTCCAA GTCCGGCTCCCCCTTTTCCCCCCGGCCGCCAGGGTGCCTGCACCTACACGCATGCGCTGCATGACGCGCCCCCCACACGCATGTCGCACC CCTCCTGCGCTCCGGGAACGCACGGACACGGGCCAGGGGGCGGGGCGATTGGGGAGGAATGAATGGCGGGGGGTCTTCCTGAGCTCCGCG GCTCACCCTCCCCAACACACACACACACACACACAGAGCAATAAGTTTCTCTCACTCAAATGTGGGCGGGGCGGGCCTAGCCTGTCGCTG GTGGGGGGAGTGGTGAGGGGGCGCTCTCAGGGATGGGGGCGGGGTTCGGAGACAGTGTGGGGAGGGGAGGTCTGCAAATCGTCCAACTCT GGTGCTAATGGCGGGTCTTCTCAGCCCACCCGCAGGGCAGGGAGGGAGGGGTCGGCGTGGCCCCTTCCCCAAGCCTCCCCCACGCCCACC CTGGGTGCATGAACCGCCCAATGCAGAAGCTGCCGCATGTCACCCCCCTCTCCCCAAAGAAAAAGTGTCATGCCCCCTTCCCACCCACCC >91845_91845_4_TMEM189-KCNC3_TMEM189_chr20_48770054_ENST00000371650_KCNC3_chr19_50827339_ENST00000376959_length(amino acids)=525AA_BP=1 MGGRGGGDRKSREVSGGDKSFSDGAIRGRGIVGEEEAGSVPAIAATASRRDGALVFRGHGRLVNGWAVLVGKRSCCRIPIGARICPVDLN HLLLSQRARLAGGWQRRQPHDPQPTRSPPEQPGVRVGPRWVGPGHSHPHGGWGDGWRRADAPAAVVRVGRGWRGWVRLAVVGRARLRGPG DVFVLLLGQLLLGHGQRIVHAKVVDNDGHRHGDGQHPRQGTQRPDQHPRPRLGVHVSIAQGRHGDHSPPEANGDVLEVGVVGAQDVIGVG ANALSVVNHGGEDEHPQGQEDDEQQELVGAGAERVSQHAQPHEVPGQLEDAQDADEADHPQEAQHVFGGLGAEAREAHLEIEGQDGHTVD DVEAAFKKLHLVWAEGDAHEELEGEPDHAHPLHVGQEGLRLHLHVGDVLRRCPGDRGGLGHRLVANMDEALMGFQAEGGDGDEDEEEGGE -------------------------------------------------------------- >91845_91845_5_TMEM189-KCNC3_TMEM189_chr20_48770054_ENST00000371652_KCNC3_chr19_50827339_ENST00000376959_length(transcript)=4631nt_BP=218nt GCTGGGCGGTCATTGGGCGGCGTGATCTCGCCGCGGTTCCGCGGCCCTGCCGCCGCCGCCGCCAGCAGAGCGCACCGGGCCGATCGGGCG AGTGGCCATGGCGGGCGCCGAGAACTGGCCGGGCCAGCAGCTGGAGCTGGACGAGGACGAGGCGTCTTGTTGCCGCTGGGGCGCGCAGCA CGCCGGGGCCCGCGAGCTGGCTGCGCTCTACTCGCCAGTATGTGGCCTTCGCCTCCCTCTTCTTCATCCTCATCTCCATCACCACCTTCT GCCTGGAAACCCATGAGGGCTTCATCCATATTAGCAACAAGACGGTGACCCAGGCCTCCCCGATCCCCGGGGCACCTCCGGAGAACATCA CCAACGTGGAGGTGGAGACGGAGCCCTTCCTGACCTACGTGGAGGGGGTGTGCGTGGTCTGGTTCACCTTCGAGTTCCTCATGCGCATCA CCTTCTGCCCAGACAAGGTGGAGTTTCTTAAAAGCAGCCTCAACATCATCGACTGTGTGGCCATCCTGCCCTTCTATCTCGAGGTGGGCC TCTCGGGCCTCAGCTCCAAGGCCGCCAAAGACGTGCTGGGCTTCCTGCGGGTGGTCCGCTTCGTCCGCATCCTGCGCATCTTCAAGCTGA CCCGGCACTTCGTGGGGCTGCGCGTGCTGGGACACACGCTCCGCGCCAGCACCAACGAGTTCCTGCTGCTCATCATCTTCCTGGCCCTGG GGGTGCTCATCTTCGCCACCATGATTTACTACGCTGAGCGCATTGGCGCCGACCCCGATGACATCCTGGGCTCCAACCACACCTACTTCA AGAACATCCCCATTGGCTTCTGGTGGGCTGTGGTCACCATGACGACCCTGGGCTATGGAGACATGTACCCCAAGACGTGGTCGGGGATGC TGGTCGGGGCGCTGTGTGCCCTGGCGGGGGTGCTGACCATCGCCATGCCTGTGCCCGTCATTGTCAACAACTTTGGCATGTACTATTCGC TGGCCATGGCCAAGCAGAAGCTGCCCAAGAAGAAGAACAAACACATCCCCCGGCCCCCGCAACCGGGCTCGCCCAACTACTGCAAGCCTG ACCCACCCCCGCCACCCCCGCCCCACCCGCACCACGGCAGCGGGGGCATCAGCCCGCCGCCACCCATCACCCCACCCTCCATGGGGGTGA CTGTGGCCGGGGCCTACCCAGCGGGGCCCCACACGCACCCCGGGCTGCTCAGGGGGGGAGCGGGTGGGCTGGGGATCATGGGGCTGCCTC CTCTGCCAGCCCCCGGCGAGCCTTGCCCGTTGGCTCAGGAGGAGGTGATTGAGATCAACCGGGCAGATCCTCGCCCCAATGGGGATCCGG CAGCAGCTGCGCTTGCCCACGAGGACTGCCCAGCCATTGACCAGCCTGCCATGTCCCCGGAAGACAAGAGCCCCATCACGCCTGGAAGCC GTGGCCGCTATAGCCGGGACCGAGCCTGCTTCCTCCTCACCGACTATGCCCCTTCCCCTGATGGCTCCATCCGAAAAGCTCTTGTCACCG CCTGAGACCTCGCGAGACTTTCGGTCCCCCCCGCCCCTTCCCCCCAGGTTACGAGAAATCCCGCAGCCTCAGCAGCATCGCGGGCCTGAG CGGGGTGTCCCTGCGCCTCGCGCCCCTTGCCACCCCCCCTGGCTCTCCCCGGGCCGCCCGCCGCGCTCCCCCGACCCTGCCCTCCATCCT TTAGCGCTCCCCTCCCCCCTGTGGGGGGACTCGGGGGTGACCGGGAAGAAGGTCAAAGGAGCTGGGGGTGGGGGGTGGGGAAAAGGGTTT TTTTAAAAAAAATCAAAAAGTCATTAATAATATGCAACCGAGATGACGATGCCAGCAGACACCCCCGGGCCCCTCACCCCCAACCTGGGC CCCCAGGATGGAGAGAGGGGCCACAGCCCGTCCCCCCAACTCTTCCCTCCCCAAAAAAAGCCTTCTCAGGTCTCCACGAGCCATAGGACA TCCCCCTGCCATCAACTTGTGTAAATAAGTCCAAATTATGCCAGTTACATCTTGGGGCACCTCCCCCCACACACTGCATGCCTTCCCTAA CCTGGAGCCCCCACTCCAAGTCCACCTCAGCAATAAGCCGCCAGGGGCCGCATGCGCGGGTTTGAGGGGCAGGCACTCTGGGAAGGGGGT GGCACCTCCCGGGGGTCGGGCTGGCCTTTAAGGTCTCCAGCCTTCCCATCCTTCACCCCAGGAGGACAACCAACCCTGTGCGTTGATTAG GAGAAAACAAACCAGAAACTAGAAACAGTGTAGGGGAAGGAGGAACAGTTACCCAAGCCCCAGATCGGAGTTGAGCTCAGGTGGCGGGAG GGCGGGGCCGAGTTGAGCTCAGGTGGTGGGAGGGCGGGGCGGGCTTTGGACCTGCTCCCTCAGCCTTTAGGAGAATTCCTCTGGTGAATT TCACCCTCTCATCCGCCCCTTCCCCCAGGGACCTGCTCGCCTCTATTCTTGCTGCATGGACTCAGACCTCCTATCCCAGAATTCCTGGGA TGATCTGGCCCTAGCACACGAAATTCCCCGACTATCTCCCTCCATTCCCAGGACATGAGACCTGCACCCAGAATTCTGAGACTGACCCTG GCACGCCACATCTCCCAATCCCCACACACTCCTGCGACTTAACCTCTGCACACAGAGGCTCCCTGAACCACCCTCCCTCCCCACTCCTGC CACCCCAAACACCCCCACCAAATTCCCTGAACTGCGTCCCAGCACTTCTCAAACCTCCAAGACTTGACCCAGCTCTTTTCAGCTCAAATT CAGCCTTTGGGATGCTCCAAATCCTTCCCACAACTGACATTTCTTGGACACCCCCAAAGCCTCAGGCCTGTTCCGCACCCATATCCCCAA AGCCCTAACAGACTTGTCCAGCCCAGGTTCCCTTGATGCTAGAACTTCCAAGATAGGCGCAACCTGTCTGCAATTCCAGGGAACCAGACC CTCCCCAAGCACCCTCTTTGTCTTACGCCTAACCCTGAGTCTCTTCCCTGAGATGGTGCCCCAAAGGTACCCTCTTCACAGACACCAGTG TTTCCCAGAGGGTTGTATTTGTACCTTTGGTGGTGTGCTAAGGTTTGAGGCAGTATGAGGACAAACACTTGTTTTAAAAGTTTTGTCTCT AATACGCATTTTGTACAGAAGCCGATAAGTGCAGGCATCGCTGCTTGGCTAGGACACGGTTTATTTAGGTTAAGAGTGTTTCCATTTAAA GTAGTCCACAGATGATCACAGAGGCTGTTCCCGAAGGGAGGAACACTGGAGTATCAGAAGATTGGGAACCGACAACACCCAGCTCGGCTG GGATCCCAGCCCCCCTTCCCCAGCGGTCCTCACCGCGTCACGCTCGCGGGTGGAAAATCATTTCCCACCTCCTATCCTGGCTCAAGGATG CGCTACCTCCCCCAAGCCCAGAGACCACACCGGTCCCAGACTCTTTAGCGGACCCCCCTTTTGGAGCCGGGGTCCCACGGAATTAGCCAC CTCCCTCCCTCTGCTCCCACGGCCTCAGGAACCCCCCACCCGAGGGTGGATGGGGGGCGTCACTGAGCACGATTCTCGATGCAACGATTC CTATGCAAGGGGCATTTTGAGTCCCCCCCATCCTTCCCTCGGACCCTAAACCCTGGTGAAGCAGGGGTGAGGGGTGGGGCGGGTTTTGGT GGGGGCGGGGCAAAGGGCTAGGGGCTCCAGACACCAGGGTACGGGGTGGGGACTGATTATATTGCCAAAGGGTTCAACTTCTTTAACAAG CCCCCCCGTTTCCCCTGACCTTCACGAAAGCCGAAGGAGGCGGGGAAAGGGGGTGAGGGTCTTTTCCAAAGGGTACTGACCTCTTCCCAA CGTCTCCCCCTGCTCGCCAGTCCGCCACACGTACCCAGCTTTTGAGTTCAGCTTTTCAAAATAACCACAATCATGATAAACTTCTACAAA ACGTGATTCTCCTCCCCTCCCACCCCATCCCCCAAGTCAATAGTGTGGGATTCGGGGAGGGAGAGAGCGAGCTAAAGGGACTCTTTCCAA GTCCGGCTCCCCCTTTTCCCCCCGGCCGCCAGGGTGCCTGCACCTACACGCATGCGCTGCATGACGCGCCCCCCACACGCATGTCGCACC CCTCCTGCGCTCCGGGAACGCACGGACACGGGCCAGGGGGCGGGGCGATTGGGGAGGAATGAATGGCGGGGGGTCTTCCTGAGCTCCGCG GCTCACCCTCCCCAACACACACACACACACACACAGAGCAATAAGTTTCTCTCACTCAAATGTGGGCGGGGCGGGCCTAGCCTGTCGCTG GTGGGGGGAGTGGTGAGGGGGCGCTCTCAGGGATGGGGGCGGGGTTCGGAGACAGTGTGGGGAGGGGAGGTCTGCAAATCGTCCAACTCT GGTGCTAATGGCGGGTCTTCTCAGCCCACCCGCAGGGCAGGGAGGGAGGGGTCGGCGTGGCCCCTTCCCCAAGCCTCCCCCACGCCCACC CTGGGTGCATGAACCGCCCAATGCAGAAGCTGCCGCATGTCACCCCCCTCTCCCCAAAGAAAAAGTGTCATGCCCCCTTCCCACCCACCC >91845_91845_5_TMEM189-KCNC3_TMEM189_chr20_48770054_ENST00000371652_KCNC3_chr19_50827339_ENST00000376959_length(amino acids)=525AA_BP=1 MGGRGGGDRKSREVSGGDKSFSDGAIRGRGIVGEEEAGSVPAIAATASRRDGALVFRGHGRLVNGWAVLVGKRSCCRIPIGARICPVDLN HLLLSQRARLAGGWQRRQPHDPQPTRSPPEQPGVRVGPRWVGPGHSHPHGGWGDGWRRADAPAAVVRVGRGWRGWVRLAVVGRARLRGPG DVFVLLLGQLLLGHGQRIVHAKVVDNDGHRHGDGQHPRQGTQRPDQHPRPRLGVHVSIAQGRHGDHSPPEANGDVLEVGVVGAQDVIGVG ANALSVVNHGGEDEHPQGQEDDEQQELVGAGAERVSQHAQPHEVPGQLEDAQDADEADHPQEAQHVFGGLGAEAREAHLEIEGQDGHTVD DVEAAFKKLHLVWAEGDAHEELEGEPDHAHPLHVGQEGLRLHLHVGDVLRRCPGDRGGLGHRLVANMDEALMGFQAEGGDGDEDEEEGGE -------------------------------------------------------------- >91845_91845_6_TMEM189-KCNC3_TMEM189_chr20_48770054_ENST00000557021_KCNC3_chr19_50827339_ENST00000376959_length(transcript)=4695nt_BP=282nt AGCCCCGATTGGCTGTGACGCGCGGCCGGGCGAGGACCCCGCCCGCGCCGCCGCCGCGCCCGGCGCTGGGCGGTCATTGGGCGGCGTGAT CTCGCCGCGGTTCCGCGGCCCTGCCGCCGCCGCCGCCAGCAGAGCGCACCGGGCCGATCGGGCGAGTGGCCATGGCGGGCGCCGAGAACT GGCCGGGCCAGCAGCTGGAGCTGGACGAGGACGAGGCGTCTTGTTGCCGCTGGGGCGCGCAGCACGCCGGGGCCCGCGAGCTGGCTGCGC TCTACTCGCCAGTATGTGGCCTTCGCCTCCCTCTTCTTCATCCTCATCTCCATCACCACCTTCTGCCTGGAAACCCATGAGGGCTTCATC CATATTAGCAACAAGACGGTGACCCAGGCCTCCCCGATCCCCGGGGCACCTCCGGAGAACATCACCAACGTGGAGGTGGAGACGGAGCCC TTCCTGACCTACGTGGAGGGGGTGTGCGTGGTCTGGTTCACCTTCGAGTTCCTCATGCGCATCACCTTCTGCCCAGACAAGGTGGAGTTT CTTAAAAGCAGCCTCAACATCATCGACTGTGTGGCCATCCTGCCCTTCTATCTCGAGGTGGGCCTCTCGGGCCTCAGCTCCAAGGCCGCC AAAGACGTGCTGGGCTTCCTGCGGGTGGTCCGCTTCGTCCGCATCCTGCGCATCTTCAAGCTGACCCGGCACTTCGTGGGGCTGCGCGTG CTGGGACACACGCTCCGCGCCAGCACCAACGAGTTCCTGCTGCTCATCATCTTCCTGGCCCTGGGGGTGCTCATCTTCGCCACCATGATT TACTACGCTGAGCGCATTGGCGCCGACCCCGATGACATCCTGGGCTCCAACCACACCTACTTCAAGAACATCCCCATTGGCTTCTGGTGG GCTGTGGTCACCATGACGACCCTGGGCTATGGAGACATGTACCCCAAGACGTGGTCGGGGATGCTGGTCGGGGCGCTGTGTGCCCTGGCG GGGGTGCTGACCATCGCCATGCCTGTGCCCGTCATTGTCAACAACTTTGGCATGTACTATTCGCTGGCCATGGCCAAGCAGAAGCTGCCC AAGAAGAAGAACAAACACATCCCCCGGCCCCCGCAACCGGGCTCGCCCAACTACTGCAAGCCTGACCCACCCCCGCCACCCCCGCCCCAC CCGCACCACGGCAGCGGGGGCATCAGCCCGCCGCCACCCATCACCCCACCCTCCATGGGGGTGACTGTGGCCGGGGCCTACCCAGCGGGG CCCCACACGCACCCCGGGCTGCTCAGGGGGGGAGCGGGTGGGCTGGGGATCATGGGGCTGCCTCCTCTGCCAGCCCCCGGCGAGCCTTGC CCGTTGGCTCAGGAGGAGGTGATTGAGATCAACCGGGCAGATCCTCGCCCCAATGGGGATCCGGCAGCAGCTGCGCTTGCCCACGAGGAC TGCCCAGCCATTGACCAGCCTGCCATGTCCCCGGAAGACAAGAGCCCCATCACGCCTGGAAGCCGTGGCCGCTATAGCCGGGACCGAGCC TGCTTCCTCCTCACCGACTATGCCCCTTCCCCTGATGGCTCCATCCGAAAAGCTCTTGTCACCGCCTGAGACCTCGCGAGACTTTCGGTC CCCCCCGCCCCTTCCCCCCAGGTTACGAGAAATCCCGCAGCCTCAGCAGCATCGCGGGCCTGAGCGGGGTGTCCCTGCGCCTCGCGCCCC TTGCCACCCCCCCTGGCTCTCCCCGGGCCGCCCGCCGCGCTCCCCCGACCCTGCCCTCCATCCTTTAGCGCTCCCCTCCCCCCTGTGGGG GGACTCGGGGGTGACCGGGAAGAAGGTCAAAGGAGCTGGGGGTGGGGGGTGGGGAAAAGGGTTTTTTTAAAAAAAATCAAAAAGTCATTA ATAATATGCAACCGAGATGACGATGCCAGCAGACACCCCCGGGCCCCTCACCCCCAACCTGGGCCCCCAGGATGGAGAGAGGGGCCACAG CCCGTCCCCCCAACTCTTCCCTCCCCAAAAAAAGCCTTCTCAGGTCTCCACGAGCCATAGGACATCCCCCTGCCATCAACTTGTGTAAAT AAGTCCAAATTATGCCAGTTACATCTTGGGGCACCTCCCCCCACACACTGCATGCCTTCCCTAACCTGGAGCCCCCACTCCAAGTCCACC TCAGCAATAAGCCGCCAGGGGCCGCATGCGCGGGTTTGAGGGGCAGGCACTCTGGGAAGGGGGTGGCACCTCCCGGGGGTCGGGCTGGCC TTTAAGGTCTCCAGCCTTCCCATCCTTCACCCCAGGAGGACAACCAACCCTGTGCGTTGATTAGGAGAAAACAAACCAGAAACTAGAAAC AGTGTAGGGGAAGGAGGAACAGTTACCCAAGCCCCAGATCGGAGTTGAGCTCAGGTGGCGGGAGGGCGGGGCCGAGTTGAGCTCAGGTGG TGGGAGGGCGGGGCGGGCTTTGGACCTGCTCCCTCAGCCTTTAGGAGAATTCCTCTGGTGAATTTCACCCTCTCATCCGCCCCTTCCCCC AGGGACCTGCTCGCCTCTATTCTTGCTGCATGGACTCAGACCTCCTATCCCAGAATTCCTGGGATGATCTGGCCCTAGCACACGAAATTC CCCGACTATCTCCCTCCATTCCCAGGACATGAGACCTGCACCCAGAATTCTGAGACTGACCCTGGCACGCCACATCTCCCAATCCCCACA CACTCCTGCGACTTAACCTCTGCACACAGAGGCTCCCTGAACCACCCTCCCTCCCCACTCCTGCCACCCCAAACACCCCCACCAAATTCC CTGAACTGCGTCCCAGCACTTCTCAAACCTCCAAGACTTGACCCAGCTCTTTTCAGCTCAAATTCAGCCTTTGGGATGCTCCAAATCCTT CCCACAACTGACATTTCTTGGACACCCCCAAAGCCTCAGGCCTGTTCCGCACCCATATCCCCAAAGCCCTAACAGACTTGTCCAGCCCAG GTTCCCTTGATGCTAGAACTTCCAAGATAGGCGCAACCTGTCTGCAATTCCAGGGAACCAGACCCTCCCCAAGCACCCTCTTTGTCTTAC GCCTAACCCTGAGTCTCTTCCCTGAGATGGTGCCCCAAAGGTACCCTCTTCACAGACACCAGTGTTTCCCAGAGGGTTGTATTTGTACCT TTGGTGGTGTGCTAAGGTTTGAGGCAGTATGAGGACAAACACTTGTTTTAAAAGTTTTGTCTCTAATACGCATTTTGTACAGAAGCCGAT AAGTGCAGGCATCGCTGCTTGGCTAGGACACGGTTTATTTAGGTTAAGAGTGTTTCCATTTAAAGTAGTCCACAGATGATCACAGAGGCT GTTCCCGAAGGGAGGAACACTGGAGTATCAGAAGATTGGGAACCGACAACACCCAGCTCGGCTGGGATCCCAGCCCCCCTTCCCCAGCGG TCCTCACCGCGTCACGCTCGCGGGTGGAAAATCATTTCCCACCTCCTATCCTGGCTCAAGGATGCGCTACCTCCCCCAAGCCCAGAGACC ACACCGGTCCCAGACTCTTTAGCGGACCCCCCTTTTGGAGCCGGGGTCCCACGGAATTAGCCACCTCCCTCCCTCTGCTCCCACGGCCTC AGGAACCCCCCACCCGAGGGTGGATGGGGGGCGTCACTGAGCACGATTCTCGATGCAACGATTCCTATGCAAGGGGCATTTTGAGTCCCC CCCATCCTTCCCTCGGACCCTAAACCCTGGTGAAGCAGGGGTGAGGGGTGGGGCGGGTTTTGGTGGGGGCGGGGCAAAGGGCTAGGGGCT CCAGACACCAGGGTACGGGGTGGGGACTGATTATATTGCCAAAGGGTTCAACTTCTTTAACAAGCCCCCCCGTTTCCCCTGACCTTCACG AAAGCCGAAGGAGGCGGGGAAAGGGGGTGAGGGTCTTTTCCAAAGGGTACTGACCTCTTCCCAACGTCTCCCCCTGCTCGCCAGTCCGCC ACACGTACCCAGCTTTTGAGTTCAGCTTTTCAAAATAACCACAATCATGATAAACTTCTACAAAACGTGATTCTCCTCCCCTCCCACCCC ATCCCCCAAGTCAATAGTGTGGGATTCGGGGAGGGAGAGAGCGAGCTAAAGGGACTCTTTCCAAGTCCGGCTCCCCCTTTTCCCCCCGGC CGCCAGGGTGCCTGCACCTACACGCATGCGCTGCATGACGCGCCCCCCACACGCATGTCGCACCCCTCCTGCGCTCCGGGAACGCACGGA CACGGGCCAGGGGGCGGGGCGATTGGGGAGGAATGAATGGCGGGGGGTCTTCCTGAGCTCCGCGGCTCACCCTCCCCAACACACACACAC ACACACACAGAGCAATAAGTTTCTCTCACTCAAATGTGGGCGGGGCGGGCCTAGCCTGTCGCTGGTGGGGGGAGTGGTGAGGGGGCGCTC TCAGGGATGGGGGCGGGGTTCGGAGACAGTGTGGGGAGGGGAGGTCTGCAAATCGTCCAACTCTGGTGCTAATGGCGGGTCTTCTCAGCC CACCCGCAGGGCAGGGAGGGAGGGGTCGGCGTGGCCCCTTCCCCAAGCCTCCCCCACGCCCACCCTGGGTGCATGAACCGCCCAATGCAG AAGCTGCCGCATGTCACCCCCCTCTCCCCAAAGAAAAAGTGTCATGCCCCCTTCCCACCCACCCTCACTCCCCACCAAAATAAACGTTTC >91845_91845_6_TMEM189-KCNC3_TMEM189_chr20_48770054_ENST00000557021_KCNC3_chr19_50827339_ENST00000376959_length(amino acids)=547AA_BP=1 MGGRGGGDRKSREVSGGDKSFSDGAIRGRGIVGEEEAGSVPAIAATASRRDGALVFRGHGRLVNGWAVLVGKRSCCRIPIGARICPVDLN HLLLSQRARLAGGWQRRQPHDPQPTRSPPEQPGVRVGPRWVGPGHSHPHGGWGDGWRRADAPAAVVRVGRGWRGWVRLAVVGRARLRGPG DVFVLLLGQLLLGHGQRIVHAKVVDNDGHRHGDGQHPRQGTQRPDQHPRPRLGVHVSIAQGRHGDHSPPEANGDVLEVGVVGAQDVIGVG ANALSVVNHGGEDEHPQGQEDDEQQELVGAGAERVSQHAQPHEVPGQLEDAQDADEADHPQEAQHVFGGLGAEAREAHLEIEGQDGHTVD DVEAAFKKLHLVWAEGDAHEELEGEPDHAHPLHVGQEGLRLHLHVGDVLRRCPGDRGGLGHRLVANMDEALMGFQAEGGDGDEDEEEGGE GHILASRAQPARGPRRAARPSGNKTPRPRPAPAAGPASSRRPPWPLARSARCALLAAAAAGPRNRGEITPPNDRPAPGAAAARAGSSPGR -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for TMEM189-KCNC3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for TMEM189-KCNC3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for TMEM189-KCNC3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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