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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TMF1-FRMD4B (FusionGDB2 ID:92306)

Fusion Gene Summary for TMF1-FRMD4B

check button Fusion gene summary
Fusion gene informationFusion gene name: TMF1-FRMD4B
Fusion gene ID: 92306
HgeneTgene
Gene symbol

TMF1

FRMD4B

Gene ID

7110

23150

Gene nameTATA element modulatory factor 1FERM domain containing 4B
SynonymsARA160|TMF6030440G05Rik|GRSP1
Cytomap

3p14.1

3p14.1

Type of geneprotein-codingprotein-coding
DescriptionTATA element modulatory factorandrogen receptor coactivator 160 kDa proteinandrogen receptor-associated protein of 160 kDaFERM domain-containing protein 4BGRP1-binding protein GRSP1
Modification date2020031320200313
UniProtAcc.

Q9Y2L6

Ensembl transtripts involved in fusion geneENST00000398559, ENST00000543976, 
ENST00000489370, 		ENST00000478263, 
ENST00000497757, ENST00000398540, 
ENST00000542259, 
Fusion gene scores* DoF score3 X 6 X 3=5412 X 12 X 10=1440
# samples 514
** MAII scorelog2(5/54*10)=-0.111031312388744
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/1440*10)=-3.36257007938471
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TMF1 [Title/Abstract] AND FRMD4B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTMF1(69077377)-FRMD4B(69362668), # samples:1
TMF1(69075147)-FRMD4B(69362668), # samples:1
TMF1(69078683)-FRMD4B(69307340), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across TMF1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FRMD4B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AC-A8OQ-01ATMF1chr3

69075147

-FRMD4Bchr3

69362668

-
ChimerDB4BRCATCGA-AC-A8OQ-01ATMF1chr3

69077377

-FRMD4Bchr3

69362668

-
ChiTaRS5.0N/AEC515959TMF1chr3

69078683

+FRMD4Bchr3

69307340

+


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Fusion Gene ORF analysis for TMF1-FRMD4B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000398559ENST00000478263TMF1chr3

69075147

-FRMD4Bchr3

69362668

-
5CDS-intronENST00000398559ENST00000478263TMF1chr3

69077377

-FRMD4Bchr3

69362668

-
5CDS-intronENST00000398559ENST00000497757TMF1chr3

69075147

-FRMD4Bchr3

69362668

-
5CDS-intronENST00000398559ENST00000497757TMF1chr3

69077377

-FRMD4Bchr3

69362668

-
5CDS-intronENST00000543976ENST00000478263TMF1chr3

69075147

-FRMD4Bchr3

69362668

-
5CDS-intronENST00000543976ENST00000478263TMF1chr3

69077377

-FRMD4Bchr3

69362668

-
5CDS-intronENST00000543976ENST00000497757TMF1chr3

69075147

-FRMD4Bchr3

69362668

-
5CDS-intronENST00000543976ENST00000497757TMF1chr3

69077377

-FRMD4Bchr3

69362668

-
5UTR-3CDSENST00000489370ENST00000398540TMF1chr3

69075147

-FRMD4Bchr3

69362668

-
5UTR-3CDSENST00000489370ENST00000542259TMF1chr3

69075147

-FRMD4Bchr3

69362668

-
5UTR-intronENST00000489370ENST00000478263TMF1chr3

69075147

-FRMD4Bchr3

69362668

-
5UTR-intronENST00000489370ENST00000497757TMF1chr3

69075147

-FRMD4Bchr3

69362668

-
In-frameENST00000398559ENST00000398540TMF1chr3

69075147

-FRMD4Bchr3

69362668

-
In-frameENST00000398559ENST00000398540TMF1chr3

69077377

-FRMD4Bchr3

69362668

-
In-frameENST00000398559ENST00000542259TMF1chr3

69075147

-FRMD4Bchr3

69362668

-
In-frameENST00000398559ENST00000542259TMF1chr3

69077377

-FRMD4Bchr3

69362668

-
In-frameENST00000543976ENST00000398540TMF1chr3

69075147

-FRMD4Bchr3

69362668

-
In-frameENST00000543976ENST00000398540TMF1chr3

69077377

-FRMD4Bchr3

69362668

-
In-frameENST00000543976ENST00000542259TMF1chr3

69075147

-FRMD4Bchr3

69362668

-
In-frameENST00000543976ENST00000542259TMF1chr3

69077377

-FRMD4Bchr3

69362668

-
intron-3CDSENST00000489370ENST00000398540TMF1chr3

69077377

-FRMD4Bchr3

69362668

-
intron-3CDSENST00000489370ENST00000542259TMF1chr3

69077377

-FRMD4Bchr3

69362668

-
intron-intronENST00000398559ENST00000398540TMF1chr3

69078683

+FRMD4Bchr3

69307340

+
intron-intronENST00000398559ENST00000478263TMF1chr3

69078683

+FRMD4Bchr3

69307340

+
intron-intronENST00000398559ENST00000497757TMF1chr3

69078683

+FRMD4Bchr3

69307340

+
intron-intronENST00000398559ENST00000542259TMF1chr3

69078683

+FRMD4Bchr3

69307340

+
intron-intronENST00000489370ENST00000398540TMF1chr3

69078683

+FRMD4Bchr3

69307340

+
intron-intronENST00000489370ENST00000478263TMF1chr3

69077377

-FRMD4Bchr3

69362668

-
intron-intronENST00000489370ENST00000478263TMF1chr3

69078683

+FRMD4Bchr3

69307340

+
intron-intronENST00000489370ENST00000497757TMF1chr3

69077377

-FRMD4Bchr3

69362668

-
intron-intronENST00000489370ENST00000497757TMF1chr3

69078683

+FRMD4Bchr3

69307340

+
intron-intronENST00000489370ENST00000542259TMF1chr3

69078683

+FRMD4Bchr3

69307340

+
intron-intronENST00000543976ENST00000398540TMF1chr3

69078683

+FRMD4Bchr3

69307340

+
intron-intronENST00000543976ENST00000478263TMF1chr3

69078683

+FRMD4Bchr3

69307340

+
intron-intronENST00000543976ENST00000497757TMF1chr3

69078683

+FRMD4Bchr3

69307340

+
intron-intronENST00000543976ENST00000542259TMF1chr3

69078683

+FRMD4Bchr3

69307340

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000398559TMF1chr369077377-ENST00000398540FRMD4Bchr369362668-7695288121758231868
ENST00000398559TMF1chr369077377-ENST00000542259FRMD4Bchr369362668-7690288121758231868
ENST00000543976TMF1chr369077377-ENST00000398540FRMD4Bchr369362668-7734292024758621871
ENST00000543976TMF1chr369077377-ENST00000542259FRMD4Bchr369362668-7729292024758621871
ENST00000398559TMF1chr369075147-ENST00000398540FRMD4Bchr369362668-7890307621760181933
ENST00000398559TMF1chr369075147-ENST00000542259FRMD4Bchr369362668-7885307621760181933
ENST00000543976TMF1chr369075147-ENST00000398540FRMD4Bchr369362668-7929311524760571936
ENST00000543976TMF1chr369075147-ENST00000542259FRMD4Bchr369362668-7924311524760571936

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000398559ENST00000398540TMF1chr369077377-FRMD4Bchr369362668-0.002463860.9975362
ENST00000398559ENST00000542259TMF1chr369077377-FRMD4Bchr369362668-0.0022932310.9977068
ENST00000543976ENST00000398540TMF1chr369077377-FRMD4Bchr369362668-0.0024923050.9975077
ENST00000543976ENST00000542259TMF1chr369077377-FRMD4Bchr369362668-0.00231710.9976829
ENST00000398559ENST00000398540TMF1chr369075147-FRMD4Bchr369362668-0.0018759950.99812394
ENST00000398559ENST00000542259TMF1chr369075147-FRMD4Bchr369362668-0.0017286650.99827135
ENST00000543976ENST00000398540TMF1chr369075147-FRMD4Bchr369362668-0.0019074980.9980925
ENST00000543976ENST00000542259TMF1chr369075147-FRMD4Bchr369362668-0.0017498820.99825007

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Fusion Genomic Features for TMF1-FRMD4B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TMF1-FRMD4B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:69077377/chr3:69362668)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.FRMD4B

Q9Y2L6

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex. Plays a redundant role with FRMD4A in epithelial polarization. {ECO:0000250|UniProtKB:Q920B0}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTMF1chr3:69075147chr3:69362668ENST00000398559-1417439_9229531094.0Coiled coilOntology_term=ECO:0000255
HgeneTMF1chr3:69075147chr3:69362668ENST00000543976-1417439_9229561097.0Coiled coilOntology_term=ECO:0000255
TgeneFRMD4Bchr3:69075147chr3:69362668ENST00000398540023417_450541035.0Coiled coilOntology_term=ECO:0000255
TgeneFRMD4Bchr3:69075147chr3:69362668ENST00000398540023531_561541035.0Coiled coilOntology_term=ECO:0000255
TgeneFRMD4Bchr3:69077377chr3:69362668ENST00000398540023417_450541035.0Coiled coilOntology_term=ECO:0000255
TgeneFRMD4Bchr3:69077377chr3:69362668ENST00000398540023531_561541035.0Coiled coilOntology_term=ECO:0000255
TgeneFRMD4Bchr3:69075147chr3:69362668ENST0000039854002359_361541035.0DomainFERM
TgeneFRMD4Bchr3:69077377chr3:69362668ENST0000039854002359_361541035.0DomainFERM
TgeneFRMD4Bchr3:69075147chr3:69362668ENST00000398540023542_971541035.0RegionNecessary for adherens junction and tight junction localization
TgeneFRMD4Bchr3:69077377chr3:69362668ENST00000398540023542_971541035.0RegionNecessary for adherens junction and tight junction localization

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTMF1chr3:69075147chr3:69362668ENST00000398559-1417984_10929531094.0Coiled coilOntology_term=ECO:0000255
HgeneTMF1chr3:69075147chr3:69362668ENST00000543976-1417984_10929561097.0Coiled coilOntology_term=ECO:0000255
HgeneTMF1chr3:69077377chr3:69362668ENST00000398559-1217439_9228881094.0Coiled coilOntology_term=ECO:0000255
HgeneTMF1chr3:69077377chr3:69362668ENST00000398559-1217984_10928881094.0Coiled coilOntology_term=ECO:0000255
HgeneTMF1chr3:69077377chr3:69362668ENST00000543976-1217439_9228911097.0Coiled coilOntology_term=ECO:0000255
HgeneTMF1chr3:69077377chr3:69362668ENST00000543976-1217984_10928911097.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for TMF1-FRMD4B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>92306_92306_1_TMF1-FRMD4B_TMF1_chr3_69075147_ENST00000398559_FRMD4B_chr3_69362668_ENST00000398540_length(transcript)=7890nt_BP=3076nt
GCAAGCGCATGCGCACATGGGCCCCCTTCGTCTCAGCTGTGCGGGAACGGCCGAGGGTAACATCCCGGGCTCGCGGGAGGCTGTCGGGGT
AATGGCCACACGCTGACAGAACCAGCCGAGTGGAAAAGGGGAGCGAAGCCGTTCCTCTGCACCCTTCCCCAGGCCTGAGGCCTTCCCGCT
TGGTGCTGCCGCCGCCACTGCCGGCTGAGGAGGGGCGATGAGTTGGTTCAACGCCTCCCAGCTCTCCAGCTTCGCTAAGCAGGCCCTGTC
CCAGGCCCAGAAGTCTATTGACAGGGTTCTGGACATCCAGGAAGAGGAGCCGAGCATCTGGGCCGAGACCATTCCGTATGGAGAGCCGGG
AATAAGTTCCCCTGTCAGTGGAGGATGGGATACTTCAACCTGGGGGTTGAAATCAAACACTGAACCTCAGAGTCCACCAATAGCCTCTCC
TAAAGCAATCACAAAGCCAGTTCGGAGGACTGTGGTCGATGAATCTGAAAATTTCTTCAGTGCCTTTCTCTCGCCAACTGATGTCCAGAC
CATTCAGAAGAGTCCAGTGGTATCAAAACCTCCAGCAAAATCACAACGACCAGAAGAAGAAGTGAAAAGCAGCTTACATGAATCCTTGCA
CATTGGCCAGTCAAGAACTCCTGAAACAACTGAATCACAAGTAAAAGACTCTTCTTTGTGTGTTTCAGGGGAAACTCTGGCAGCAGGTAC
TTCATCACCTAAAACTGAAGGCAAGCACGAAGAAACTGTTAATAAAGAATCGGATATGAAGGTGCCAACTGTAAGTTTGAAAGTATCTGA
AAGTGTAATTGATGTGAAAACAACTATGGAAAGTATATCTAATACGTCTACGCAGTCTCTCACAGCAGAAACAAAGGACATAGCTTTGGA
ACCTAAGGAACAAAAACATGAAGACAGGCAGAGCAATACACCTTCTCCTCCTGTTAGTACCTTTTCATCAGGTACTTCTACCACCAGTGA
TATTGAAGTTTTAGATCATGAAAGTGTAATAAGTGAGAGCTCAGCGAGCTCGAGACAAGAGACTACAGATTCAAAATCAAGTCTTCACTT
GATGCAGACATCTTTTCAGCTTCTCTCTGCATCTGCTTGTCCTGAATATAATCGTTTAGATGATTTCCAAAAACTCACTGAGAGTTGCTG
TTCATCTGATGCTTTTGAAAGAATAGACTCATTTAGTGTACAGTCATTAGATAGCCGGAGTGTAAGTGAAATCAATTCAGATGATGAATT
GTCAGGCAAGGGATATGCTTTAGTGCCTATTATAGTTAATTCTTCAACTCCAAAGTCTAAAACAGTTGAATCTGCTGAAGGAAAATCTGA
AGAAGTAAATGAAACATTAGTTATACCCACTGAGGAAGCAGAAATGGAAGAAAGTGGACGAAGTGCAACTCCTGTTAACTGTGAACAGCC
TGATATCTTGGTTTCTTCCACACCAATAAATGAAGGACAGACTGTGTTAGACAAGGTGGCTGAGCAGTGTGAACCTGCTGAAAGTCAGCC
AGAAGCACTTTCTGAGAAGGAAGATGTTTGCAAGACAGTTGAATTTCTGAATGAAAAGCTGGAAAAAAGGGAGGCTCAGTTATTATCTCT
TAGTAAGGAAAAAGCACTTCTAGAAGAAGCTTTTGATAACCTGAAAGATGAAATGTTCAGAGTGAAAGAAGAAAGCAGTAGCATTTCTTC
CTTGAAAGATGAGTTTACTCAAAGAATTGCAGAAGCAGAAAAGAAAGTTCAACTAGCCTGCAAAGAGAGAGATGCTGCTAAAAAGGAAAT
CAAAAACATAAAAGAAGAACTTGCCACTAGATTAAATAGTAGTGAAACTGCAGACCTTTTGAAAGAGAAAGATGAGCAGATCCGAGGGTT
AATGGAAGAAGGAGAAAAACTTTCAAAACAGCAGCTGCACAATTCTAACATCATCAAGAAATTAAGAGCTAAAGACAAGGAGAATGAAAA
TATGGTTGCAAAGCTGAACAAAAAAGTTAAAGAGCTAGAAGAGGAGTTGCAGCATTTGAAACAGGTCCTTGATGGCAAAGAAGAGGTTGA
GAAACAACATAGAGAAAATATTAAAAAACTAAATTCCATGGTAGAACGCCAAGAGAAAGATCTTGGCCGTCTTCAGGTAGACATGGATGA
ACTTGAAGAAAAGAACCGAAGTATTCAGGCTGCCCTGGATAGTGCATACAAAGAACTTACTGATCTTCACAAAGCCAATGCTGCAAAGGA
TAGTGAGGCACAGGAAGCTGCTCTGAGCCGTGAAATGAAAGCTAAAGAAGAACTTTCTGCAGCATTAGAGAAGGCCCAAGAAGAAGCCCG
TCAGCAGCAAGAAACATTAGCCATTCAAGTGGGGGACCTTAGGCTTGCATTGCAGCGTACAGAACAAGCGGCTGCCAGAAAGGAGGATTA
TTTACGCCATGAGATCGGTGAACTTCAGCAGAGACTCCAGGAAGCAGAGAATCGAAACCAGGAACTGAGTCAAAGTGTTTCATCAACAAC
AAGACCATTGCTTCGACAAATAGAAAATTTGCAAGCAACCCTGGGATCCCAGACATCGTCGTGGGAGAAATTAGAGAAGAATCTTTCTGA
TAGGCTTGGTGAATCCCAGACCTTGCTGGCAGCAGCAGTTGAGAGAGAACGTGCAGCTACAGAAGAACTCCTTGCTAACAAAATTCAGAT
GTCTTCCATGGAGTCACAGAATTCTCTTTTAAGACAGGAAAACAGTAGATTTCAAGCCCAGCTAGAATCAGAGAAAAATAGGCTGTGTAA
ACTGGAGGATGAGAACAATAGGTACCAGGTTGAATTGGAAAACCTAAAAGATGAATATGTAAGAACACTTGAAGAGACGAGGAAAGAAAA
GACATTGTTGAATAGTCAGTTAGAAATGGAAAGAATGAAAGTTGAACAAGAAAGGAAGAAAGCCATTTTTACTCAAGAAACAATAAAAGA
AAAGGAACGCAAGCCATTTTCTGTTTCTAGCACTCCCACCATGTCACGCTCAAGTTCAATAAGTGGTGTTGATATGGCAGGACTACAGAC
ATCTTTTCTGTCTCAGATGACAGAAGGCAGGCACTGCCAGGTGCACCTCCTGGATGATAGGAGACTGGAGCTGCTGGTTCAGCCCAAACT
TCTAGCAAGAGAGTTGCTGGACCTAGTGGCTTCACATTTCAACCTGAAAGAAAAGGAGTATTTTGGAATAACATTCATAGATGACACAGG
TCAGCAGAACTGGCTGCAGTTAGATCACCGAGTTCTTGACCACGATTTGCCCAAGAAACCAGGCCCAACCATTTTGCACTTTGCTGTGAG
GTTTTACATTGAGAGCATATCGTTTTTAAAGGATAAAACCACCGTGGAGCTGTTTTTCCTGAATGCAAAGGCCTGTGTGCACAAGGGGCA
AATCGAAGTAGAGAGCGAAACCATCTTCAAGTTAGCAGCGTTTATTTTACAGGAAGCCAAGGGAGATTATACCAGTGATGAAAATGCCAG
GAAAGATTTAAAGACATTACCAGCCTTTCCAACCAAAACTCTTCAGGAGCATCCATCCCTTGCCTACTGTGAGGACAGGGTAATTGAGCA
TTATTTGAAAATCAAAGGTCTCACTCGAGGTCAAGCTGTGGTTCAGTATATGAAAATAGTAGAAGCTCTACCGACTTACGGTGTCCATTA
TTATGCAGTAAAGGATAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTATAAGGGAATTGGCCAATATGATATACAAGACAAGGTGAA
GCCTCGGAAGTTATTCCAATGGAAACAGCTGGAGAACTTATATTTCCGTGAGAAAAAATTTGCTGTTGAAGTTCATGATCCACGAAGGAT
TTCAGTTTCAAGAAGAACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATGGTATGCTAACTCTTCTCTCATCAAGTCCATTTGGGTAAT
GGCAATTAGTCAGCATCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAAAATTCCTTCAGCCAGGAGTTTAGATGAGATTGCAATGGA
TTTGACAGAGACAGGAACACAAAGGGCCTCCAAGCTGGTGACACTGGAGACGAAAAGTCAGTTCATCATGGCAAGTAATGGCAGTTTAAT
CTCCTCAGGTTCTCAAGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAAAATCCTTGAACTAAAGAAGAAGGAGAAACTATTACAAGA
AAAACTTCTGAAAAAAGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGCTGAGCTCACAGGCAAAATGCCAAAGGAGTATCCCCTGAA
CATAGGCGAGAAGCCTCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAAATTAGATGACAACTTGCTGCCGAGTGAAGAAGATCCTGC
TTTGCAAGAACTGGAGAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGCTGCAAAGAAACTTGCCAATGAGCCAGACCTTTGTAAAAC
TGTGAAGAAAAAGCGAAAGCAAGATTACACAGATGCGATGAAAAAGCTTCAGGAGATTGAAAATGCAATAAACGAATACCGAATTAGGTG
TGGAAAGAAACCCAGCCAGAAAGCAACAGTGTTACCAGAAGACATAATCCCCTCAGAGAGTAGCTCTTTGTCTGACACCACCACCTATGA
TGATCCCAGTGATGCCTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACCTCATTCTCCAAGAATTCTTCCCCCCAAGTCTCTTGGTAT
TGAGCGAATCCATTTCAGAAAGTCGTCCATCAATGAACAGTTTGTGGATACCAGGCAGTCCAGAGAAATGCTGTCCACACACAGCAGCCC
TTACAAAACTCTGGAGAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCACGCCAGTTCTTACCCGAAACGCCTACAGCAGCAGCCACTT
GGAACCCGAATCTTCATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGAGTCCCAGTCCCACCTGCTCTCCGAGATGGACAGCGATAA
GCCATTTTTCTCCCTCTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCTCGATGACGGGTCTTCTTATACAAGCCAATCAAGCACAGA
GTATTACTGTGTGACACCAGTTACCGGCCCCTATTACACCACCCAGACCCTGGACACTCGCACCAGGGGTCGGAGGAGGTCAAAGAAACA
GAATGTTTCTACTTCAAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGATAGTTTGAGGAATGGTGTTTACTCAAAGAGTCAGGAGCC
ACCGTCTTCCAGTTACTACATTGCCGGGTACACACCCTATGCAGAGTGTGACTTTTATTACAGTGGTGGTTATGTCTATGAGAATGACAC
CGAGGGACAGTATAGTGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGGATATGAGCGCCAGAGGGACTACAGCAGATCCTTTCACGA
AGATGAGGTCGACCGGGTACCCCATAACCCATATGCAACTCTCCGGCTGCCAAGGAAGGCTGCTGCAAAATCGGAGCACATCACCAAAAA
CATCCACAAGGCCTTAGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGCCTCTGGGCAGAAGGATCAGGGACACAGCCCGCAGACCAG
CTTTGACTCAGACAGGGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCAAGTACCTTGTTCTCCAAGCAGTCGTGCATCCTCGTACTC
TTCAGTGTCTTCTACAAATGCTTCTGGGAACTGGAGGACCCAGTTAACCATAGGGCTGTCGGATTACGAGACTCCAGCACATTCTTCTTA
CACCAGCTGCTATGGCAATGTCTATAATCCTTTACCCTCTCCAAGCAGACAATACACAGAAATCAGTCAACTGGATGGTACAGATGGAAA
CCAGCTGGAAGACAACCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGAAGATTCAAAGCCTGGAACATTAGTCTGAACTGCAGTTGG
ACCTCCTGACCAAGCACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTATTTGTCTTCCGAGAGGATGTTCGTTTTAGAAACCTAAAG
ACATCAAAGGTTGAAGAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAATCACACACCAAGCCCCACAAAGCCCCTAAAGGAGGATTT
GGCCTTTCAAACTCTAGGCACTAACGTAACTGTAGGGTCTGCCCACATGTTGAAGTATTGCCAAGAGAGGACTCAGTGTGAAGCCTTCAT
CAATAGCAAGCACTTTTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAAAAACATGAAAGGGCATTCAGGATGTCCCATGGCAATAAG
AACAGGGGAAATCTCAGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCAGAAGCTCCGGAGTCATTGCTCACTTCAGAGTTTGAATTC
GTGAGCTGACAAAGAGTAACATGCTCTTTCTACACAGACATGGACAATTTAGACAGTATTGGAAAATTACTTGAAGCTGGATTTTCATGA
AGTTCTGAATGAGTGTAAATGTTTTTTAGGATACTATAAAGAGTGATGTTTTTCATAAGCACCATAAAATGGGTTCTGGAAAAACTGATT
ACCTTAGCATCCTGTAATATAACTTATGGTAGCAGATTGGGGAAAATGAAGCAGCCCACTGAATAATTGACAAAGTCTGCTTGGAGAACA
TTCTAAGGTACAATATCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCGTGATGAGCTATTGTTCTGGCTGTTAATTCTCCAACTCGG
CTGTCATTTGAAGTGGCAGACTTAATATGGAAAGTTTTTATAATTATGAGTTTGAAAAAGCATTTTAAGATGATACAGAAAGTATCCAAA
ACAACAGAAAAAAAAAGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAATGGTGAACGTTAGAAAATTAAACAAGTCTGGATTCCACA
AGTAGTTCCAAGTCACCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAAAAACAACAACAACGACAAAAAGCTCCAAGCTGCAGTGGA
TTTAATTATGAGGCTAAAACTACCTCATACTTTCCTTGGAAGAACTAATTAGCTATGGTTTATTGTAGGGTTTTGTTTGTTTGTTTTTTA
AAGCAAATGATTTCCATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTCAAAATTACATAAAAGGTGCTCCTTTCCCCCTTCTTTTAT
ACAAGTTTCTTGTTCATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTTGGAACATTTTCTATCTATATTCCAAAGCATGTAATATAT
ACATAAAAACGATTTGTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAATGAAGTTTGGGAAAAAATTTTGGAAAAAAGACAAGCAAA
AAAAAATAACTTATTCCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAGAAATAACCTTTTTGCATATTCTTTTATTGTTCTGACTTT
TCAAGACCTATTATTTTTTTACATAGGTCAATAAACAAAAGGTGTGCTACTGAAAATGTTTACGTTTTCTTCCATTTATGTCAGGGGTTC
ATGTGAAGCAGGTCGCAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGCTTCGGATTTTTATTTATAGTATTACCGTATTTTATTAAT
TCCGGGATGTACATTTTTAAATATTTACATTAAAAACATGGTTCATCTTTTTATTGATGGCATATTCTACTTGAATTGGCAGTTTTTTCT

>92306_92306_1_TMF1-FRMD4B_TMF1_chr3_69075147_ENST00000398559_FRMD4B_chr3_69362668_ENST00000398540_length(amino acids)=1933AA_BP=952
MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTSTWGLKSNTEPQSPPIASPKAITKPVRRTVV
DESENFFSAFLSPTDVQTIQKSPVVSKPPAKSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEET
VNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSNTPSPPVSTFSSGTSTTSDIEVLDHESVISE
SSASSRQETTDSKSSLHLMQTSFQLLSASACPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIV
NSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKT
VEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELATRLN
SSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNS
MVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGD
LRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSDRLGESQTLLAAA
VERERAATEELLANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERM
KVEQERKKAIFTQETIKEKERKPFSVSSTPTMSRSSSISGVDMAGLQTSFLSQMTEGRHCQVHLLDDRRLELLVQPKLLARELLDLVASH
FNLKEKEYFGITFIDDTGQQNWLQLDHRVLDHDLPKKPGPTILHFAVRFYIESISFLKDKTTVELFFLNAKACVHKGQIEVESETIFKLA
AFILQEAKGDYTSDENARKDLKTLPAFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGLPWW
LGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRK
QSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQFIMASNGSLISSGSQDSEVSEEQKREKILELKKKEKLLQEKLLKKVEELKKI
CLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQKLVEAAKKLANEPDLCKTVKKKRKQDYTDA
MKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESSSLSDTTTYDDPSDAFTFPGQRSSSVPHSPRILPPKSLGIERIHFRKSSINE
QFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPESSSQHCRQRSGSLESQSHLLSEMDSDKPFFSLSKSQRSS
STEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRTRGRRRSKKQNVSTSNSGSMPNLAQKDSLRNGVYSKSQEPPSSSYYIAGYTP
YAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQRDYSRSFHEDEVDRVPHNPYATLRLPRKAAAKSEHITKNIHKALVAEHLRG
WYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQLTIGLSDYETPAHSSYTSCYGNVYNPLP

--------------------------------------------------------------
>92306_92306_2_TMF1-FRMD4B_TMF1_chr3_69075147_ENST00000398559_FRMD4B_chr3_69362668_ENST00000542259_length(transcript)=7885nt_BP=3076nt
GCAAGCGCATGCGCACATGGGCCCCCTTCGTCTCAGCTGTGCGGGAACGGCCGAGGGTAACATCCCGGGCTCGCGGGAGGCTGTCGGGGT
AATGGCCACACGCTGACAGAACCAGCCGAGTGGAAAAGGGGAGCGAAGCCGTTCCTCTGCACCCTTCCCCAGGCCTGAGGCCTTCCCGCT
TGGTGCTGCCGCCGCCACTGCCGGCTGAGGAGGGGCGATGAGTTGGTTCAACGCCTCCCAGCTCTCCAGCTTCGCTAAGCAGGCCCTGTC
CCAGGCCCAGAAGTCTATTGACAGGGTTCTGGACATCCAGGAAGAGGAGCCGAGCATCTGGGCCGAGACCATTCCGTATGGAGAGCCGGG
AATAAGTTCCCCTGTCAGTGGAGGATGGGATACTTCAACCTGGGGGTTGAAATCAAACACTGAACCTCAGAGTCCACCAATAGCCTCTCC
TAAAGCAATCACAAAGCCAGTTCGGAGGACTGTGGTCGATGAATCTGAAAATTTCTTCAGTGCCTTTCTCTCGCCAACTGATGTCCAGAC
CATTCAGAAGAGTCCAGTGGTATCAAAACCTCCAGCAAAATCACAACGACCAGAAGAAGAAGTGAAAAGCAGCTTACATGAATCCTTGCA
CATTGGCCAGTCAAGAACTCCTGAAACAACTGAATCACAAGTAAAAGACTCTTCTTTGTGTGTTTCAGGGGAAACTCTGGCAGCAGGTAC
TTCATCACCTAAAACTGAAGGCAAGCACGAAGAAACTGTTAATAAAGAATCGGATATGAAGGTGCCAACTGTAAGTTTGAAAGTATCTGA
AAGTGTAATTGATGTGAAAACAACTATGGAAAGTATATCTAATACGTCTACGCAGTCTCTCACAGCAGAAACAAAGGACATAGCTTTGGA
ACCTAAGGAACAAAAACATGAAGACAGGCAGAGCAATACACCTTCTCCTCCTGTTAGTACCTTTTCATCAGGTACTTCTACCACCAGTGA
TATTGAAGTTTTAGATCATGAAAGTGTAATAAGTGAGAGCTCAGCGAGCTCGAGACAAGAGACTACAGATTCAAAATCAAGTCTTCACTT
GATGCAGACATCTTTTCAGCTTCTCTCTGCATCTGCTTGTCCTGAATATAATCGTTTAGATGATTTCCAAAAACTCACTGAGAGTTGCTG
TTCATCTGATGCTTTTGAAAGAATAGACTCATTTAGTGTACAGTCATTAGATAGCCGGAGTGTAAGTGAAATCAATTCAGATGATGAATT
GTCAGGCAAGGGATATGCTTTAGTGCCTATTATAGTTAATTCTTCAACTCCAAAGTCTAAAACAGTTGAATCTGCTGAAGGAAAATCTGA
AGAAGTAAATGAAACATTAGTTATACCCACTGAGGAAGCAGAAATGGAAGAAAGTGGACGAAGTGCAACTCCTGTTAACTGTGAACAGCC
TGATATCTTGGTTTCTTCCACACCAATAAATGAAGGACAGACTGTGTTAGACAAGGTGGCTGAGCAGTGTGAACCTGCTGAAAGTCAGCC
AGAAGCACTTTCTGAGAAGGAAGATGTTTGCAAGACAGTTGAATTTCTGAATGAAAAGCTGGAAAAAAGGGAGGCTCAGTTATTATCTCT
TAGTAAGGAAAAAGCACTTCTAGAAGAAGCTTTTGATAACCTGAAAGATGAAATGTTCAGAGTGAAAGAAGAAAGCAGTAGCATTTCTTC
CTTGAAAGATGAGTTTACTCAAAGAATTGCAGAAGCAGAAAAGAAAGTTCAACTAGCCTGCAAAGAGAGAGATGCTGCTAAAAAGGAAAT
CAAAAACATAAAAGAAGAACTTGCCACTAGATTAAATAGTAGTGAAACTGCAGACCTTTTGAAAGAGAAAGATGAGCAGATCCGAGGGTT
AATGGAAGAAGGAGAAAAACTTTCAAAACAGCAGCTGCACAATTCTAACATCATCAAGAAATTAAGAGCTAAAGACAAGGAGAATGAAAA
TATGGTTGCAAAGCTGAACAAAAAAGTTAAAGAGCTAGAAGAGGAGTTGCAGCATTTGAAACAGGTCCTTGATGGCAAAGAAGAGGTTGA
GAAACAACATAGAGAAAATATTAAAAAACTAAATTCCATGGTAGAACGCCAAGAGAAAGATCTTGGCCGTCTTCAGGTAGACATGGATGA
ACTTGAAGAAAAGAACCGAAGTATTCAGGCTGCCCTGGATAGTGCATACAAAGAACTTACTGATCTTCACAAAGCCAATGCTGCAAAGGA
TAGTGAGGCACAGGAAGCTGCTCTGAGCCGTGAAATGAAAGCTAAAGAAGAACTTTCTGCAGCATTAGAGAAGGCCCAAGAAGAAGCCCG
TCAGCAGCAAGAAACATTAGCCATTCAAGTGGGGGACCTTAGGCTTGCATTGCAGCGTACAGAACAAGCGGCTGCCAGAAAGGAGGATTA
TTTACGCCATGAGATCGGTGAACTTCAGCAGAGACTCCAGGAAGCAGAGAATCGAAACCAGGAACTGAGTCAAAGTGTTTCATCAACAAC
AAGACCATTGCTTCGACAAATAGAAAATTTGCAAGCAACCCTGGGATCCCAGACATCGTCGTGGGAGAAATTAGAGAAGAATCTTTCTGA
TAGGCTTGGTGAATCCCAGACCTTGCTGGCAGCAGCAGTTGAGAGAGAACGTGCAGCTACAGAAGAACTCCTTGCTAACAAAATTCAGAT
GTCTTCCATGGAGTCACAGAATTCTCTTTTAAGACAGGAAAACAGTAGATTTCAAGCCCAGCTAGAATCAGAGAAAAATAGGCTGTGTAA
ACTGGAGGATGAGAACAATAGGTACCAGGTTGAATTGGAAAACCTAAAAGATGAATATGTAAGAACACTTGAAGAGACGAGGAAAGAAAA
GACATTGTTGAATAGTCAGTTAGAAATGGAAAGAATGAAAGTTGAACAAGAAAGGAAGAAAGCCATTTTTACTCAAGAAACAATAAAAGA
AAAGGAACGCAAGCCATTTTCTGTTTCTAGCACTCCCACCATGTCACGCTCAAGTTCAATAAGTGGTGTTGATATGGCAGGACTACAGAC
ATCTTTTCTGTCTCAGATGACAGAAGGCAGGCACTGCCAGGTGCACCTCCTGGATGATAGGAGACTGGAGCTGCTGGTTCAGCCCAAACT
TCTAGCAAGAGAGTTGCTGGACCTAGTGGCTTCACATTTCAACCTGAAAGAAAAGGAGTATTTTGGAATAACATTCATAGATGACACAGG
TCAGCAGAACTGGCTGCAGTTAGATCACCGAGTTCTTGACCACGATTTGCCCAAGAAACCAGGCCCAACCATTTTGCACTTTGCTGTGAG
GTTTTACATTGAGAGCATATCGTTTTTAAAGGATAAAACCACCGTGGAGCTGTTTTTCCTGAATGCAAAGGCCTGTGTGCACAAGGGGCA
AATCGAAGTAGAGAGCGAAACCATCTTCAAGTTAGCAGCGTTTATTTTACAGTCTCCCAAAGTCTCGCTTACCCATGATGAAAATGCCAG
GAAAGATTTAAAGACATTACCAGCCTTTCCAACCAAAACTCTTCAGGAGCATCCATCCCTTGCCTACTGTGAGGACAGGGTAATTGAGCA
TTATTTGAAAATCAAAGGTCTCACTCGAGGTCAAGCTGTGGTTCAGTATATGAAAATAGTAGAAGCTCTACCGACTTACGGTGTCCATTA
TTATGCAGTAAAGGATAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTATAAGGGAATTGGCCAATATGATATACAAGACAAGGTGAA
GCCTCGGAAGTTATTCCAATGGAAACAGCTGGAGAACTTATATTTCCGTGAGAAAAAATTTGCTGTTGAAGTTCATGATCCACGAAGGAT
TTCAGTTTCAAGAAGAACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATGGTATGCTAACTCTTCTCTCATCAAGTCCATTTGGGTAAT
GGCAATTAGTCAGCATCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAAAATTCCTTCAGCCAGGAGTTTAGATGAGATTGCAATGGA
TTTGACAGAGACAGGAACACAAAGGGCCTCCAAGCTGGTGACACTGGAGACGAAAAGTCAGTTCATCATGGCAAGTAATGGCAGTTTAAT
CTCCTCAGGTTCTCAAGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAAAATCCTTGAACTAAAGAAGAAGGAGAAACTATTACAAGA
AAAACTTCTGAAAAAAGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGCTGAGCTCACAGGCAAAATGCCAAAGGAGTATCCCCTGAA
CATAGGCGAGAAGCCTCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAAATTAGATGACAACTTGCTGCCGAGTGAAGAAGATCCTGC
TTTGCAAGAACTGGAGAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGCTGCAAAGAAACTTGCCAATGAGCCAGACCTTTGTAAAAC
TGTGAAGAAAAAGCGAAAGCAAGATTACACAGATGCGATGAAAAAGCTTCAGGAGATTGAAAATGCAATAAACGAATACCGAATTAGGTG
TGGAAAGAAACCCAGCCAGAAAGCAACAGTGTTACCAGAAGACATAATCCCCTCAGAGAGTAGCTCTTTGTCTGACACCACCACCTATGA
TGATCCCAGTGATGCCTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACCTCATTCTCCAAGAATTCTTCCCCCCAAGTCTCTTGGTAT
TGAGCGAATCCATTTCAGAAAGTCGTCCATCAATGAACAGTTTGTGGATACCAGGCAGTCCAGAGAAATGCTGTCCACACACAGCAGCCC
TTACAAAACTCTGGAGAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCACGCCAGTTCTTACCCGAAACGCCTACAGCAGCAGCCACTT
GGAACCCGAATCTTCATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGAGTCCCAGTCCCACCTGCTCTCCGAGATGGACAGCGATAA
GCCATTTTTCTCCCTCTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCTCGATGACGGGTCTTCTTATACAAGCCAATCAAGCACAGA
GTATTACTGTGTGACACCAGTTACCGGCCCCTATTACACCACCCAGACCCTGGACACTCGCACCAGGGGTCGGAGGAGGTCAAAGAAACA
GAATGTTTCTACTTCAAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGATAGTTTGAGGAATGGTGTTTACTCAAAGAGTCAGGAGCC
ACCGTCTTCCAGTTACTACATTGCCGGGTACACACCCTATGCAGAGTGTGACTTTTATTACAGTGGTGGTTATGTCTATGAGAATGACAC
CGAGGGACAGTATAGTGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGGATATGAGCGCCAGAGGGACTACAGCAGATCCTTTCACGA
AGATGAGGTCGACCGGGTACCCCATAACCCATATGCAACTCTCCGGCTGCCAAGGAAGGCTGCTGCAAAATCGGAGCACATCACCAAAAA
CATCCACAAGGCCTTAGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGCCTCTGGGCAGAAGGATCAGGGACACAGCCCGCAGACCAG
CTTTGACTCAGACAGGGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCAAGTACCTTGTTCTCCAAGCAGTCGTGCATCCTCGTACTC
TTCAGTGTCTTCTACAAATGCTTCTGGGAACTGGAGGACCCAGTTAACCATAGGGCTGTCGGATTACGAGACTCCAGCACATTCTTCTTA
CACCAGCTGCTATGGCAATGTCTATAATCCTTTACCCTCTCCAAGCAGACAATACACAGAAATCAGTCAACTGGATGGTACAGATGGAAA
CCAGCTGGAAGACAACCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGAAGATTCAAAGCCTGGAACATTAGTCTGAACTGCAGTTGG
ACCTCCTGACCAAGCACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTATTTGTCTTCCGAGAGGATGTTCGTTTTAGAAACCTAAAG
ACATCAAAGGTTGAAGAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAATCACACACCAAGCCCCACAAAGCCCCTAAAGGAGGATTT
GGCCTTTCAAACTCTAGGCACTAACGTAACTGTAGGGTCTGCCCACATGTTGAAGTATTGCCAAGAGAGGACTCAGTGTGAAGCCTTCAT
CAATAGCAAGCACTTTTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAAAAACATGAAAGGGCATTCAGGATGTCCCATGGCAATAAG
AACAGGGGAAATCTCAGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCAGAAGCTCCGGAGTCATTGCTCACTTCAGAGTTTGAATTC
GTGAGCTGACAAAGAGTAACATGCTCTTTCTACACAGACATGGACAATTTAGACAGTATTGGAAAATTACTTGAAGCTGGATTTTCATGA
AGTTCTGAATGAGTGTAAATGTTTTTTAGGATACTATAAAGAGTGATGTTTTTCATAAGCACCATAAAATGGGTTCTGGAAAAACTGATT
ACCTTAGCATCCTGTAATATAACTTATGGTAGCAGATTGGGGAAAATGAAGCAGCCCACTGAATAATTGACAAAGTCTGCTTGGAGAACA
TTCTAAGGTACAATATCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCGTGATGAGCTATTGTTCTGGCTGTTAATTCTCCAACTCGG
CTGTCATTTGAAGTGGCAGACTTAATATGGAAAGTTTTTATAATTATGAGTTTGAAAAAGCATTTTAAGATGATACAGAAAGTATCCAAA
ACAACAGAAAAAAAAAGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAATGGTGAACGTTAGAAAATTAAACAAGTCTGGATTCCACA
AGTAGTTCCAAGTCACCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAAAAACAACAACAACGACAAAAAGCTCCAAGCTGCAGTGGA
TTTAATTATGAGGCTAAAACTACCTCATACTTTCCTTGGAAGAACTAATTAGCTATGGTTTATTGTAGGGTTTTGTTTGTTTGTTTTTTA
AAGCAAATGATTTCCATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTCAAAATTACATAAAAGGTGCTCCTTTCCCCCTTCTTTTAT
ACAAGTTTCTTGTTCATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTTGGAACATTTTCTATCTATATTCCAAAGCATGTAATATAT
ACATAAAAACGATTTGTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAATGAAGTTTGGGAAAAAATTTTGGAAAAAAGACAAGCAAA
AAAAAATAACTTATTCCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAGAAATAACCTTTTTGCATATTCTTTTATTGTTCTGACTTT
TCAAGACCTATTATTTTTTTACATAGGTCAATAAACAAAAGGTGTGCTACTGAAAATGTTTACGTTTTCTTCCATTTATGTCAGGGGTTC
ATGTGAAGCAGGTCGCAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGCTTCGGATTTTTATTTATAGTATTACCGTATTTTATTAAT
TCCGGGATGTACATTTTTAAATATTTACATTAAAAACATGGTTCATCTTTTTATTGATGGCATATTCTACTTGAATTGGCAGTTTTTTCT

>92306_92306_2_TMF1-FRMD4B_TMF1_chr3_69075147_ENST00000398559_FRMD4B_chr3_69362668_ENST00000542259_length(amino acids)=1933AA_BP=952
MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTSTWGLKSNTEPQSPPIASPKAITKPVRRTVV
DESENFFSAFLSPTDVQTIQKSPVVSKPPAKSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEET
VNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSNTPSPPVSTFSSGTSTTSDIEVLDHESVISE
SSASSRQETTDSKSSLHLMQTSFQLLSASACPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIV
NSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKT
VEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELATRLN
SSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNS
MVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGD
LRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSDRLGESQTLLAAA
VERERAATEELLANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERM
KVEQERKKAIFTQETIKEKERKPFSVSSTPTMSRSSSISGVDMAGLQTSFLSQMTEGRHCQVHLLDDRRLELLVQPKLLARELLDLVASH
FNLKEKEYFGITFIDDTGQQNWLQLDHRVLDHDLPKKPGPTILHFAVRFYIESISFLKDKTTVELFFLNAKACVHKGQIEVESETIFKLA
AFILQSPKVSLTHDENARKDLKTLPAFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGLPWW
LGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRK
QSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQFIMASNGSLISSGSQDSEVSEEQKREKILELKKKEKLLQEKLLKKVEELKKI
CLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQKLVEAAKKLANEPDLCKTVKKKRKQDYTDA
MKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESSSLSDTTTYDDPSDAFTFPGQRSSSVPHSPRILPPKSLGIERIHFRKSSINE
QFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPESSSQHCRQRSGSLESQSHLLSEMDSDKPFFSLSKSQRSS
STEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRTRGRRRSKKQNVSTSNSGSMPNLAQKDSLRNGVYSKSQEPPSSSYYIAGYTP
YAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQRDYSRSFHEDEVDRVPHNPYATLRLPRKAAAKSEHITKNIHKALVAEHLRG
WYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQLTIGLSDYETPAHSSYTSCYGNVYNPLP

--------------------------------------------------------------
>92306_92306_3_TMF1-FRMD4B_TMF1_chr3_69075147_ENST00000543976_FRMD4B_chr3_69362668_ENST00000398540_length(transcript)=7929nt_BP=3115nt
GTAGATTTGGTTGCTGTGTACGTGGAAGAAGCAAGCGCATGCGCACATGGGCCCCCTTCGTCTCAGCTGTGCGGGAACGGCCGAGGGTAA
CATCCCGGGCTCGCGGGAGGCTGTCGGGGTAATGGCCACACGCTGACAGAACCAGCCGAGTGGAAAAGGGGAGCGAAGCCGTTCCTCTGC
ACCCTTCCCCAGGCCTGAGGCCTTCCCGCTTGGTGCTGCCGCCGCCACTGCCGGCTGAGGAGGGGCGATGAGTTGGTTCAACGCCTCCCA
GCTCTCCAGCTTCGCTAAGCAGGCCCTGTCCCAGGCCCAGAAGTCTATTGACAGGGTTCTGGACATCCAGGAAGAGGAGCCGAGCATCTG
GGCCGAGACCATTCCGTATGGAGAGCCGGGAATAAGTTCCCCTGTCAGTGGAGGATGGGATACTTCAACCTGGGGGTTGAAATCAAACAC
TGAACCTCAGAGTCCACCAATAGCCTCTCCTAAAGCAATCACAAAGCCAGTTCGGAGGACTGTGGTCGATGAATCTGAAAATTTCTTCAG
TGCCTTTCTCTCGCCAACTGATGTCCAGACCATTCAGAAGAGTCCAGTGGTATCAAAACCTCCAGCAAAATCACAACGACCAGAAGAAGA
AGTGAAAAGCAGCTTACATGAATCCTTGCACATTGGCCAGTCAAGAACTCCTGAAACAACTGAATCACAAGTAAAAGACTCTTCTTTGTG
TGTTTCAGGGGAAACTCTGGCAGCAGGTACTTCATCACCTAAAACTGAAGGCAAGCACGAAGAAACTGTTAATAAAGAATCGGATATGAA
GGTGCCAACTGTAAGTTTGAAAGTATCTGAAAGTGTAATTGATGTGAAAACAACTATGGAAAGTATATCTAATACGTCTACGCAGTCTCT
CACAGCAGAAACAAAGGACATAGCTTTGGAACCTAAGGAACAAAAACATGAAGACAGGCAGAGCAATACACCTTCTCCTCCTGTTAGTAC
CTTTTCATCAGGTACTTCTACCACCAGTGATATTGAAGTTTTAGATCATGAAAGTGTAATAAGTGAGAGCTCAGCGAGCTCGAGACAAGA
GACTACAGATTCAAAATCAAGTCTTCACTTGATGCAGACATCTTTTCAGCTTCTCTCTGCATCTGCTTGTCCTGAATATAATCGTTTAGA
TGATTTCCAAAAACTCACTGAGAGTTGCTGTTCATCTGATGCTTTTGAAAGAATAGACTCATTTAGTGTACAGTCATTAGATAGCCGGAG
TGTAAGTGAAATCAATTCAGATGATGAATTGTCAGGCAAGGGATATGCTTTAGTGCCTATTATAGTTAATTCTTCAACTCCAAAGTCTAA
AACAGTTGAATCTGCTGAAGGAAAATCTGAAGAAGTAAATGAAACATTAGTTATACCCACTGAGGAAGCAGAAATGGAAGAAAGTGGACG
AAGTGCAACTCCTGTTAACTGTGAACAGCCTGATATCTTGGTTTCTTCCACACCAATAAATGAAGGACAGACTGTGTTAGACAAGGTGGC
TGAGCAGTGTGAACCTGCTGAAAGTCAGCCAGAAGCACTTTCTGAGAAGGAAGATGTTTGCAAGGTAACTCTAACAGTTGAATTTCTGAA
TGAAAAGCTGGAAAAAAGGGAGGCTCAGTTATTATCTCTTAGTAAGGAAAAAGCACTTCTAGAAGAAGCTTTTGATAACCTGAAAGATGA
AATGTTCAGAGTGAAAGAAGAAAGCAGTAGCATTTCTTCCTTGAAAGATGAGTTTACTCAAAGAATTGCAGAAGCAGAAAAGAAAGTTCA
ACTAGCCTGCAAAGAGAGAGATGCTGCTAAAAAGGAAATCAAAAACATAAAAGAAGAACTTGCCACTAGATTAAATAGTAGTGAAACTGC
AGACCTTTTGAAAGAGAAAGATGAGCAGATCCGAGGGTTAATGGAAGAAGGAGAAAAACTTTCAAAACAGCAGCTGCACAATTCTAACAT
CATCAAGAAATTAAGAGCTAAAGACAAGGAGAATGAAAATATGGTTGCAAAGCTGAACAAAAAAGTTAAAGAGCTAGAAGAGGAGTTGCA
GCATTTGAAACAGGTCCTTGATGGCAAAGAAGAGGTTGAGAAACAACATAGAGAAAATATTAAAAAACTAAATTCCATGGTAGAACGCCA
AGAGAAAGATCTTGGCCGTCTTCAGGTAGACATGGATGAACTTGAAGAAAAGAACCGAAGTATTCAGGCTGCCCTGGATAGTGCATACAA
AGAACTTACTGATCTTCACAAAGCCAATGCTGCAAAGGATAGTGAGGCACAGGAAGCTGCTCTGAGCCGTGAAATGAAAGCTAAAGAAGA
ACTTTCTGCAGCATTAGAGAAGGCCCAAGAAGAAGCCCGTCAGCAGCAAGAAACATTAGCCATTCAAGTGGGGGACCTTAGGCTTGCATT
GCAGCGTACAGAACAAGCGGCTGCCAGAAAGGAGGATTATTTACGCCATGAGATCGGTGAACTTCAGCAGAGACTCCAGGAAGCAGAGAA
TCGAAACCAGGAACTGAGTCAAAGTGTTTCATCAACAACAAGACCATTGCTTCGACAAATAGAAAATTTGCAAGCAACCCTGGGATCCCA
GACATCGTCGTGGGAGAAATTAGAGAAGAATCTTTCTGATAGGCTTGGTGAATCCCAGACCTTGCTGGCAGCAGCAGTTGAGAGAGAACG
TGCAGCTACAGAAGAACTCCTTGCTAACAAAATTCAGATGTCTTCCATGGAGTCACAGAATTCTCTTTTAAGACAGGAAAACAGTAGATT
TCAAGCCCAGCTAGAATCAGAGAAAAATAGGCTGTGTAAACTGGAGGATGAGAACAATAGGTACCAGGTTGAATTGGAAAACCTAAAAGA
TGAATATGTAAGAACACTTGAAGAGACGAGGAAAGAAAAGACATTGTTGAATAGTCAGTTAGAAATGGAAAGAATGAAAGTTGAACAAGA
AAGGAAGAAAGCCATTTTTACTCAAGAAACAATAAAAGAAAAGGAACGCAAGCCATTTTCTGTTTCTAGCACTCCCACCATGTCACGCTC
AAGTTCAATAAGTGGTGTTGATATGGCAGGACTACAGACATCTTTTCTGTCTCAGATGACAGAAGGCAGGCACTGCCAGGTGCACCTCCT
GGATGATAGGAGACTGGAGCTGCTGGTTCAGCCCAAACTTCTAGCAAGAGAGTTGCTGGACCTAGTGGCTTCACATTTCAACCTGAAAGA
AAAGGAGTATTTTGGAATAACATTCATAGATGACACAGGTCAGCAGAACTGGCTGCAGTTAGATCACCGAGTTCTTGACCACGATTTGCC
CAAGAAACCAGGCCCAACCATTTTGCACTTTGCTGTGAGGTTTTACATTGAGAGCATATCGTTTTTAAAGGATAAAACCACCGTGGAGCT
GTTTTTCCTGAATGCAAAGGCCTGTGTGCACAAGGGGCAAATCGAAGTAGAGAGCGAAACCATCTTCAAGTTAGCAGCGTTTATTTTACA
GGAAGCCAAGGGAGATTATACCAGTGATGAAAATGCCAGGAAAGATTTAAAGACATTACCAGCCTTTCCAACCAAAACTCTTCAGGAGCA
TCCATCCCTTGCCTACTGTGAGGACAGGGTAATTGAGCATTATTTGAAAATCAAAGGTCTCACTCGAGGTCAAGCTGTGGTTCAGTATAT
GAAAATAGTAGAAGCTCTACCGACTTACGGTGTCCATTATTATGCAGTAAAGGATAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTA
TAAGGGAATTGGCCAATATGATATACAAGACAAGGTGAAGCCTCGGAAGTTATTCCAATGGAAACAGCTGGAGAACTTATATTTCCGTGA
GAAAAAATTTGCTGTTGAAGTTCATGATCCACGAAGGATTTCAGTTTCAAGAAGAACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATG
GTATGCTAACTCTTCTCTCATCAAGTCCATTTGGGTAATGGCAATTAGTCAGCATCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAA
AATTCCTTCAGCCAGGAGTTTAGATGAGATTGCAATGGATTTGACAGAGACAGGAACACAAAGGGCCTCCAAGCTGGTGACACTGGAGAC
GAAAAGTCAGTTCATCATGGCAAGTAATGGCAGTTTAATCTCCTCAGGTTCTCAAGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAA
AATCCTTGAACTAAAGAAGAAGGAGAAACTATTACAAGAAAAACTTCTGAAAAAAGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGC
TGAGCTCACAGGCAAAATGCCAAAGGAGTATCCCCTGAACATAGGCGAGAAGCCTCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAA
ATTAGATGACAACTTGCTGCCGAGTGAAGAAGATCCTGCTTTGCAAGAACTGGAGAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGC
TGCAAAGAAACTTGCCAATGAGCCAGACCTTTGTAAAACTGTGAAGAAAAAGCGAAAGCAAGATTACACAGATGCGATGAAAAAGCTTCA
GGAGATTGAAAATGCAATAAACGAATACCGAATTAGGTGTGGAAAGAAACCCAGCCAGAAAGCAACAGTGTTACCAGAAGACATAATCCC
CTCAGAGAGTAGCTCTTTGTCTGACACCACCACCTATGATGATCCCAGTGATGCCTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACC
TCATTCTCCAAGAATTCTTCCCCCCAAGTCTCTTGGTATTGAGCGAATCCATTTCAGAAAGTCGTCCATCAATGAACAGTTTGTGGATAC
CAGGCAGTCCAGAGAAATGCTGTCCACACACAGCAGCCCTTACAAAACTCTGGAGAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCAC
GCCAGTTCTTACCCGAAACGCCTACAGCAGCAGCCACTTGGAACCCGAATCTTCATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGA
GTCCCAGTCCCACCTGCTCTCCGAGATGGACAGCGATAAGCCATTTTTCTCCCTCTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCT
CGATGACGGGTCTTCTTATACAAGCCAATCAAGCACAGAGTATTACTGTGTGACACCAGTTACCGGCCCCTATTACACCACCCAGACCCT
GGACACTCGCACCAGGGGTCGGAGGAGGTCAAAGAAACAGAATGTTTCTACTTCAAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGA
TAGTTTGAGGAATGGTGTTTACTCAAAGAGTCAGGAGCCACCGTCTTCCAGTTACTACATTGCCGGGTACACACCCTATGCAGAGTGTGA
CTTTTATTACAGTGGTGGTTATGTCTATGAGAATGACACCGAGGGACAGTATAGTGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGG
ATATGAGCGCCAGAGGGACTACAGCAGATCCTTTCACGAAGATGAGGTCGACCGGGTACCCCATAACCCATATGCAACTCTCCGGCTGCC
AAGGAAGGCTGCTGCAAAATCGGAGCACATCACCAAAAACATCCACAAGGCCTTAGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGC
CTCTGGGCAGAAGGATCAGGGACACAGCCCGCAGACCAGCTTTGACTCAGACAGGGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCA
AGTACCTTGTTCTCCAAGCAGTCGTGCATCCTCGTACTCTTCAGTGTCTTCTACAAATGCTTCTGGGAACTGGAGGACCCAGTTAACCAT
AGGGCTGTCGGATTACGAGACTCCAGCACATTCTTCTTACACCAGCTGCTATGGCAATGTCTATAATCCTTTACCCTCTCCAAGCAGACA
ATACACAGAAATCAGTCAACTGGATGGTACAGATGGAAACCAGCTGGAAGACAACCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGA
AGATTCAAAGCCTGGAACATTAGTCTGAACTGCAGTTGGACCTCCTGACCAAGCACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTA
TTTGTCTTCCGAGAGGATGTTCGTTTTAGAAACCTAAAGACATCAAAGGTTGAAGAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAA
TCACACACCAAGCCCCACAAAGCCCCTAAAGGAGGATTTGGCCTTTCAAACTCTAGGCACTAACGTAACTGTAGGGTCTGCCCACATGTT
GAAGTATTGCCAAGAGAGGACTCAGTGTGAAGCCTTCATCAATAGCAAGCACTTTTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAA
AAACATGAAAGGGCATTCAGGATGTCCCATGGCAATAAGAACAGGGGAAATCTCAGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCA
GAAGCTCCGGAGTCATTGCTCACTTCAGAGTTTGAATTCGTGAGCTGACAAAGAGTAACATGCTCTTTCTACACAGACATGGACAATTTA
GACAGTATTGGAAAATTACTTGAAGCTGGATTTTCATGAAGTTCTGAATGAGTGTAAATGTTTTTTAGGATACTATAAAGAGTGATGTTT
TTCATAAGCACCATAAAATGGGTTCTGGAAAAACTGATTACCTTAGCATCCTGTAATATAACTTATGGTAGCAGATTGGGGAAAATGAAG
CAGCCCACTGAATAATTGACAAAGTCTGCTTGGAGAACATTCTAAGGTACAATATCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCG
TGATGAGCTATTGTTCTGGCTGTTAATTCTCCAACTCGGCTGTCATTTGAAGTGGCAGACTTAATATGGAAAGTTTTTATAATTATGAGT
TTGAAAAAGCATTTTAAGATGATACAGAAAGTATCCAAAACAACAGAAAAAAAAAGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAA
TGGTGAACGTTAGAAAATTAAACAAGTCTGGATTCCACAAGTAGTTCCAAGTCACCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAA
AAACAACAACAACGACAAAAAGCTCCAAGCTGCAGTGGATTTAATTATGAGGCTAAAACTACCTCATACTTTCCTTGGAAGAACTAATTA
GCTATGGTTTATTGTAGGGTTTTGTTTGTTTGTTTTTTAAAGCAAATGATTTCCATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTC
AAAATTACATAAAAGGTGCTCCTTTCCCCCTTCTTTTATACAAGTTTCTTGTTCATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTT
GGAACATTTTCTATCTATATTCCAAAGCATGTAATATATACATAAAAACGATTTGTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAA
TGAAGTTTGGGAAAAAATTTTGGAAAAAAGACAAGCAAAAAAAAATAACTTATTCCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAG
AAATAACCTTTTTGCATATTCTTTTATTGTTCTGACTTTTCAAGACCTATTATTTTTTTACATAGGTCAATAAACAAAAGGTGTGCTACT
GAAAATGTTTACGTTTTCTTCCATTTATGTCAGGGGTTCATGTGAAGCAGGTCGCAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGC
TTCGGATTTTTATTTATAGTATTACCGTATTTTATTAATTCCGGGATGTACATTTTTAAATATTTACATTAAAAACATGGTTCATCTTTT
TATTGATGGCATATTCTACTTGAATTGGCAGTTTTTTCTTAATAGTACATTAAAAATAATGCTGTGTCTTACAATAAAGTTGCCTTAGAA

>92306_92306_3_TMF1-FRMD4B_TMF1_chr3_69075147_ENST00000543976_FRMD4B_chr3_69362668_ENST00000398540_length(amino acids)=1936AA_BP=955
MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTSTWGLKSNTEPQSPPIASPKAITKPVRRTVV
DESENFFSAFLSPTDVQTIQKSPVVSKPPAKSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEET
VNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSNTPSPPVSTFSSGTSTTSDIEVLDHESVISE
SSASSRQETTDSKSSLHLMQTSFQLLSASACPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIV
NSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKV
TLTVEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELAT
RLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKK
LNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQ
VGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSDRLGESQTLL
AAAVERERAATEELLANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEM
ERMKVEQERKKAIFTQETIKEKERKPFSVSSTPTMSRSSSISGVDMAGLQTSFLSQMTEGRHCQVHLLDDRRLELLVQPKLLARELLDLV
ASHFNLKEKEYFGITFIDDTGQQNWLQLDHRVLDHDLPKKPGPTILHFAVRFYIESISFLKDKTTVELFFLNAKACVHKGQIEVESETIF
KLAAFILQEAKGDYTSDENARKDLKTLPAFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGL
PWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYL
DRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQFIMASNGSLISSGSQDSEVSEEQKREKILELKKKEKLLQEKLLKKVEEL
KKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQKLVEAAKKLANEPDLCKTVKKKRKQDY
TDAMKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESSSLSDTTTYDDPSDAFTFPGQRSSSVPHSPRILPPKSLGIERIHFRKSS
INEQFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPESSSQHCRQRSGSLESQSHLLSEMDSDKPFFSLSKSQ
RSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRTRGRRRSKKQNVSTSNSGSMPNLAQKDSLRNGVYSKSQEPPSSSYYIAG
YTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQRDYSRSFHEDEVDRVPHNPYATLRLPRKAAAKSEHITKNIHKALVAEH
LRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQLTIGLSDYETPAHSSYTSCYGNVYN

--------------------------------------------------------------
>92306_92306_4_TMF1-FRMD4B_TMF1_chr3_69075147_ENST00000543976_FRMD4B_chr3_69362668_ENST00000542259_length(transcript)=7924nt_BP=3115nt
GTAGATTTGGTTGCTGTGTACGTGGAAGAAGCAAGCGCATGCGCACATGGGCCCCCTTCGTCTCAGCTGTGCGGGAACGGCCGAGGGTAA
CATCCCGGGCTCGCGGGAGGCTGTCGGGGTAATGGCCACACGCTGACAGAACCAGCCGAGTGGAAAAGGGGAGCGAAGCCGTTCCTCTGC
ACCCTTCCCCAGGCCTGAGGCCTTCCCGCTTGGTGCTGCCGCCGCCACTGCCGGCTGAGGAGGGGCGATGAGTTGGTTCAACGCCTCCCA
GCTCTCCAGCTTCGCTAAGCAGGCCCTGTCCCAGGCCCAGAAGTCTATTGACAGGGTTCTGGACATCCAGGAAGAGGAGCCGAGCATCTG
GGCCGAGACCATTCCGTATGGAGAGCCGGGAATAAGTTCCCCTGTCAGTGGAGGATGGGATACTTCAACCTGGGGGTTGAAATCAAACAC
TGAACCTCAGAGTCCACCAATAGCCTCTCCTAAAGCAATCACAAAGCCAGTTCGGAGGACTGTGGTCGATGAATCTGAAAATTTCTTCAG
TGCCTTTCTCTCGCCAACTGATGTCCAGACCATTCAGAAGAGTCCAGTGGTATCAAAACCTCCAGCAAAATCACAACGACCAGAAGAAGA
AGTGAAAAGCAGCTTACATGAATCCTTGCACATTGGCCAGTCAAGAACTCCTGAAACAACTGAATCACAAGTAAAAGACTCTTCTTTGTG
TGTTTCAGGGGAAACTCTGGCAGCAGGTACTTCATCACCTAAAACTGAAGGCAAGCACGAAGAAACTGTTAATAAAGAATCGGATATGAA
GGTGCCAACTGTAAGTTTGAAAGTATCTGAAAGTGTAATTGATGTGAAAACAACTATGGAAAGTATATCTAATACGTCTACGCAGTCTCT
CACAGCAGAAACAAAGGACATAGCTTTGGAACCTAAGGAACAAAAACATGAAGACAGGCAGAGCAATACACCTTCTCCTCCTGTTAGTAC
CTTTTCATCAGGTACTTCTACCACCAGTGATATTGAAGTTTTAGATCATGAAAGTGTAATAAGTGAGAGCTCAGCGAGCTCGAGACAAGA
GACTACAGATTCAAAATCAAGTCTTCACTTGATGCAGACATCTTTTCAGCTTCTCTCTGCATCTGCTTGTCCTGAATATAATCGTTTAGA
TGATTTCCAAAAACTCACTGAGAGTTGCTGTTCATCTGATGCTTTTGAAAGAATAGACTCATTTAGTGTACAGTCATTAGATAGCCGGAG
TGTAAGTGAAATCAATTCAGATGATGAATTGTCAGGCAAGGGATATGCTTTAGTGCCTATTATAGTTAATTCTTCAACTCCAAAGTCTAA
AACAGTTGAATCTGCTGAAGGAAAATCTGAAGAAGTAAATGAAACATTAGTTATACCCACTGAGGAAGCAGAAATGGAAGAAAGTGGACG
AAGTGCAACTCCTGTTAACTGTGAACAGCCTGATATCTTGGTTTCTTCCACACCAATAAATGAAGGACAGACTGTGTTAGACAAGGTGGC
TGAGCAGTGTGAACCTGCTGAAAGTCAGCCAGAAGCACTTTCTGAGAAGGAAGATGTTTGCAAGGTAACTCTAACAGTTGAATTTCTGAA
TGAAAAGCTGGAAAAAAGGGAGGCTCAGTTATTATCTCTTAGTAAGGAAAAAGCACTTCTAGAAGAAGCTTTTGATAACCTGAAAGATGA
AATGTTCAGAGTGAAAGAAGAAAGCAGTAGCATTTCTTCCTTGAAAGATGAGTTTACTCAAAGAATTGCAGAAGCAGAAAAGAAAGTTCA
ACTAGCCTGCAAAGAGAGAGATGCTGCTAAAAAGGAAATCAAAAACATAAAAGAAGAACTTGCCACTAGATTAAATAGTAGTGAAACTGC
AGACCTTTTGAAAGAGAAAGATGAGCAGATCCGAGGGTTAATGGAAGAAGGAGAAAAACTTTCAAAACAGCAGCTGCACAATTCTAACAT
CATCAAGAAATTAAGAGCTAAAGACAAGGAGAATGAAAATATGGTTGCAAAGCTGAACAAAAAAGTTAAAGAGCTAGAAGAGGAGTTGCA
GCATTTGAAACAGGTCCTTGATGGCAAAGAAGAGGTTGAGAAACAACATAGAGAAAATATTAAAAAACTAAATTCCATGGTAGAACGCCA
AGAGAAAGATCTTGGCCGTCTTCAGGTAGACATGGATGAACTTGAAGAAAAGAACCGAAGTATTCAGGCTGCCCTGGATAGTGCATACAA
AGAACTTACTGATCTTCACAAAGCCAATGCTGCAAAGGATAGTGAGGCACAGGAAGCTGCTCTGAGCCGTGAAATGAAAGCTAAAGAAGA
ACTTTCTGCAGCATTAGAGAAGGCCCAAGAAGAAGCCCGTCAGCAGCAAGAAACATTAGCCATTCAAGTGGGGGACCTTAGGCTTGCATT
GCAGCGTACAGAACAAGCGGCTGCCAGAAAGGAGGATTATTTACGCCATGAGATCGGTGAACTTCAGCAGAGACTCCAGGAAGCAGAGAA
TCGAAACCAGGAACTGAGTCAAAGTGTTTCATCAACAACAAGACCATTGCTTCGACAAATAGAAAATTTGCAAGCAACCCTGGGATCCCA
GACATCGTCGTGGGAGAAATTAGAGAAGAATCTTTCTGATAGGCTTGGTGAATCCCAGACCTTGCTGGCAGCAGCAGTTGAGAGAGAACG
TGCAGCTACAGAAGAACTCCTTGCTAACAAAATTCAGATGTCTTCCATGGAGTCACAGAATTCTCTTTTAAGACAGGAAAACAGTAGATT
TCAAGCCCAGCTAGAATCAGAGAAAAATAGGCTGTGTAAACTGGAGGATGAGAACAATAGGTACCAGGTTGAATTGGAAAACCTAAAAGA
TGAATATGTAAGAACACTTGAAGAGACGAGGAAAGAAAAGACATTGTTGAATAGTCAGTTAGAAATGGAAAGAATGAAAGTTGAACAAGA
AAGGAAGAAAGCCATTTTTACTCAAGAAACAATAAAAGAAAAGGAACGCAAGCCATTTTCTGTTTCTAGCACTCCCACCATGTCACGCTC
AAGTTCAATAAGTGGTGTTGATATGGCAGGACTACAGACATCTTTTCTGTCTCAGATGACAGAAGGCAGGCACTGCCAGGTGCACCTCCT
GGATGATAGGAGACTGGAGCTGCTGGTTCAGCCCAAACTTCTAGCAAGAGAGTTGCTGGACCTAGTGGCTTCACATTTCAACCTGAAAGA
AAAGGAGTATTTTGGAATAACATTCATAGATGACACAGGTCAGCAGAACTGGCTGCAGTTAGATCACCGAGTTCTTGACCACGATTTGCC
CAAGAAACCAGGCCCAACCATTTTGCACTTTGCTGTGAGGTTTTACATTGAGAGCATATCGTTTTTAAAGGATAAAACCACCGTGGAGCT
GTTTTTCCTGAATGCAAAGGCCTGTGTGCACAAGGGGCAAATCGAAGTAGAGAGCGAAACCATCTTCAAGTTAGCAGCGTTTATTTTACA
GTCTCCCAAAGTCTCGCTTACCCATGATGAAAATGCCAGGAAAGATTTAAAGACATTACCAGCCTTTCCAACCAAAACTCTTCAGGAGCA
TCCATCCCTTGCCTACTGTGAGGACAGGGTAATTGAGCATTATTTGAAAATCAAAGGTCTCACTCGAGGTCAAGCTGTGGTTCAGTATAT
GAAAATAGTAGAAGCTCTACCGACTTACGGTGTCCATTATTATGCAGTAAAGGATAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTA
TAAGGGAATTGGCCAATATGATATACAAGACAAGGTGAAGCCTCGGAAGTTATTCCAATGGAAACAGCTGGAGAACTTATATTTCCGTGA
GAAAAAATTTGCTGTTGAAGTTCATGATCCACGAAGGATTTCAGTTTCAAGAAGAACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATG
GTATGCTAACTCTTCTCTCATCAAGTCCATTTGGGTAATGGCAATTAGTCAGCATCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAA
AATTCCTTCAGCCAGGAGTTTAGATGAGATTGCAATGGATTTGACAGAGACAGGAACACAAAGGGCCTCCAAGCTGGTGACACTGGAGAC
GAAAAGTCAGTTCATCATGGCAAGTAATGGCAGTTTAATCTCCTCAGGTTCTCAAGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAA
AATCCTTGAACTAAAGAAGAAGGAGAAACTATTACAAGAAAAACTTCTGAAAAAAGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGC
TGAGCTCACAGGCAAAATGCCAAAGGAGTATCCCCTGAACATAGGCGAGAAGCCTCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAA
ATTAGATGACAACTTGCTGCCGAGTGAAGAAGATCCTGCTTTGCAAGAACTGGAGAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGC
TGCAAAGAAACTTGCCAATGAGCCAGACCTTTGTAAAACTGTGAAGAAAAAGCGAAAGCAAGATTACACAGATGCGATGAAAAAGCTTCA
GGAGATTGAAAATGCAATAAACGAATACCGAATTAGGTGTGGAAAGAAACCCAGCCAGAAAGCAACAGTGTTACCAGAAGACATAATCCC
CTCAGAGAGTAGCTCTTTGTCTGACACCACCACCTATGATGATCCCAGTGATGCCTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACC
TCATTCTCCAAGAATTCTTCCCCCCAAGTCTCTTGGTATTGAGCGAATCCATTTCAGAAAGTCGTCCATCAATGAACAGTTTGTGGATAC
CAGGCAGTCCAGAGAAATGCTGTCCACACACAGCAGCCCTTACAAAACTCTGGAGAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCAC
GCCAGTTCTTACCCGAAACGCCTACAGCAGCAGCCACTTGGAACCCGAATCTTCATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGA
GTCCCAGTCCCACCTGCTCTCCGAGATGGACAGCGATAAGCCATTTTTCTCCCTCTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCT
CGATGACGGGTCTTCTTATACAAGCCAATCAAGCACAGAGTATTACTGTGTGACACCAGTTACCGGCCCCTATTACACCACCCAGACCCT
GGACACTCGCACCAGGGGTCGGAGGAGGTCAAAGAAACAGAATGTTTCTACTTCAAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGA
TAGTTTGAGGAATGGTGTTTACTCAAAGAGTCAGGAGCCACCGTCTTCCAGTTACTACATTGCCGGGTACACACCCTATGCAGAGTGTGA
CTTTTATTACAGTGGTGGTTATGTCTATGAGAATGACACCGAGGGACAGTATAGTGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGG
ATATGAGCGCCAGAGGGACTACAGCAGATCCTTTCACGAAGATGAGGTCGACCGGGTACCCCATAACCCATATGCAACTCTCCGGCTGCC
AAGGAAGGCTGCTGCAAAATCGGAGCACATCACCAAAAACATCCACAAGGCCTTAGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGC
CTCTGGGCAGAAGGATCAGGGACACAGCCCGCAGACCAGCTTTGACTCAGACAGGGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCA
AGTACCTTGTTCTCCAAGCAGTCGTGCATCCTCGTACTCTTCAGTGTCTTCTACAAATGCTTCTGGGAACTGGAGGACCCAGTTAACCAT
AGGGCTGTCGGATTACGAGACTCCAGCACATTCTTCTTACACCAGCTGCTATGGCAATGTCTATAATCCTTTACCCTCTCCAAGCAGACA
ATACACAGAAATCAGTCAACTGGATGGTACAGATGGAAACCAGCTGGAAGACAACCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGA
AGATTCAAAGCCTGGAACATTAGTCTGAACTGCAGTTGGACCTCCTGACCAAGCACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTA
TTTGTCTTCCGAGAGGATGTTCGTTTTAGAAACCTAAAGACATCAAAGGTTGAAGAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAA
TCACACACCAAGCCCCACAAAGCCCCTAAAGGAGGATTTGGCCTTTCAAACTCTAGGCACTAACGTAACTGTAGGGTCTGCCCACATGTT
GAAGTATTGCCAAGAGAGGACTCAGTGTGAAGCCTTCATCAATAGCAAGCACTTTTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAA
AAACATGAAAGGGCATTCAGGATGTCCCATGGCAATAAGAACAGGGGAAATCTCAGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCA
GAAGCTCCGGAGTCATTGCTCACTTCAGAGTTTGAATTCGTGAGCTGACAAAGAGTAACATGCTCTTTCTACACAGACATGGACAATTTA
GACAGTATTGGAAAATTACTTGAAGCTGGATTTTCATGAAGTTCTGAATGAGTGTAAATGTTTTTTAGGATACTATAAAGAGTGATGTTT
TTCATAAGCACCATAAAATGGGTTCTGGAAAAACTGATTACCTTAGCATCCTGTAATATAACTTATGGTAGCAGATTGGGGAAAATGAAG
CAGCCCACTGAATAATTGACAAAGTCTGCTTGGAGAACATTCTAAGGTACAATATCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCG
TGATGAGCTATTGTTCTGGCTGTTAATTCTCCAACTCGGCTGTCATTTGAAGTGGCAGACTTAATATGGAAAGTTTTTATAATTATGAGT
TTGAAAAAGCATTTTAAGATGATACAGAAAGTATCCAAAACAACAGAAAAAAAAAGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAA
TGGTGAACGTTAGAAAATTAAACAAGTCTGGATTCCACAAGTAGTTCCAAGTCACCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAA
AAACAACAACAACGACAAAAAGCTCCAAGCTGCAGTGGATTTAATTATGAGGCTAAAACTACCTCATACTTTCCTTGGAAGAACTAATTA
GCTATGGTTTATTGTAGGGTTTTGTTTGTTTGTTTTTTAAAGCAAATGATTTCCATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTC
AAAATTACATAAAAGGTGCTCCTTTCCCCCTTCTTTTATACAAGTTTCTTGTTCATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTT
GGAACATTTTCTATCTATATTCCAAAGCATGTAATATATACATAAAAACGATTTGTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAA
TGAAGTTTGGGAAAAAATTTTGGAAAAAAGACAAGCAAAAAAAAATAACTTATTCCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAG
AAATAACCTTTTTGCATATTCTTTTATTGTTCTGACTTTTCAAGACCTATTATTTTTTTACATAGGTCAATAAACAAAAGGTGTGCTACT
GAAAATGTTTACGTTTTCTTCCATTTATGTCAGGGGTTCATGTGAAGCAGGTCGCAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGC
TTCGGATTTTTATTTATAGTATTACCGTATTTTATTAATTCCGGGATGTACATTTTTAAATATTTACATTAAAAACATGGTTCATCTTTT
TATTGATGGCATATTCTACTTGAATTGGCAGTTTTTTCTTAATAGTACATTAAAAATAATGCTGTGTCTTACAATAAAGTTGCCTTAGAA

>92306_92306_4_TMF1-FRMD4B_TMF1_chr3_69075147_ENST00000543976_FRMD4B_chr3_69362668_ENST00000542259_length(amino acids)=1936AA_BP=955
MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTSTWGLKSNTEPQSPPIASPKAITKPVRRTVV
DESENFFSAFLSPTDVQTIQKSPVVSKPPAKSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEET
VNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSNTPSPPVSTFSSGTSTTSDIEVLDHESVISE
SSASSRQETTDSKSSLHLMQTSFQLLSASACPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIV
NSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKV
TLTVEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELAT
RLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKK
LNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQ
VGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSDRLGESQTLL
AAAVERERAATEELLANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEM
ERMKVEQERKKAIFTQETIKEKERKPFSVSSTPTMSRSSSISGVDMAGLQTSFLSQMTEGRHCQVHLLDDRRLELLVQPKLLARELLDLV
ASHFNLKEKEYFGITFIDDTGQQNWLQLDHRVLDHDLPKKPGPTILHFAVRFYIESISFLKDKTTVELFFLNAKACVHKGQIEVESETIF
KLAAFILQSPKVSLTHDENARKDLKTLPAFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGL
PWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYL
DRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQFIMASNGSLISSGSQDSEVSEEQKREKILELKKKEKLLQEKLLKKVEEL
KKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQKLVEAAKKLANEPDLCKTVKKKRKQDY
TDAMKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESSSLSDTTTYDDPSDAFTFPGQRSSSVPHSPRILPPKSLGIERIHFRKSS
INEQFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPESSSQHCRQRSGSLESQSHLLSEMDSDKPFFSLSKSQ
RSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRTRGRRRSKKQNVSTSNSGSMPNLAQKDSLRNGVYSKSQEPPSSSYYIAG
YTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQRDYSRSFHEDEVDRVPHNPYATLRLPRKAAAKSEHITKNIHKALVAEH
LRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQLTIGLSDYETPAHSSYTSCYGNVYN

--------------------------------------------------------------
>92306_92306_5_TMF1-FRMD4B_TMF1_chr3_69077377_ENST00000398559_FRMD4B_chr3_69362668_ENST00000398540_length(transcript)=7695nt_BP=2881nt
GCAAGCGCATGCGCACATGGGCCCCCTTCGTCTCAGCTGTGCGGGAACGGCCGAGGGTAACATCCCGGGCTCGCGGGAGGCTGTCGGGGT
AATGGCCACACGCTGACAGAACCAGCCGAGTGGAAAAGGGGAGCGAAGCCGTTCCTCTGCACCCTTCCCCAGGCCTGAGGCCTTCCCGCT
TGGTGCTGCCGCCGCCACTGCCGGCTGAGGAGGGGCGATGAGTTGGTTCAACGCCTCCCAGCTCTCCAGCTTCGCTAAGCAGGCCCTGTC
CCAGGCCCAGAAGTCTATTGACAGGGTTCTGGACATCCAGGAAGAGGAGCCGAGCATCTGGGCCGAGACCATTCCGTATGGAGAGCCGGG
AATAAGTTCCCCTGTCAGTGGAGGATGGGATACTTCAACCTGGGGGTTGAAATCAAACACTGAACCTCAGAGTCCACCAATAGCCTCTCC
TAAAGCAATCACAAAGCCAGTTCGGAGGACTGTGGTCGATGAATCTGAAAATTTCTTCAGTGCCTTTCTCTCGCCAACTGATGTCCAGAC
CATTCAGAAGAGTCCAGTGGTATCAAAACCTCCAGCAAAATCACAACGACCAGAAGAAGAAGTGAAAAGCAGCTTACATGAATCCTTGCA
CATTGGCCAGTCAAGAACTCCTGAAACAACTGAATCACAAGTAAAAGACTCTTCTTTGTGTGTTTCAGGGGAAACTCTGGCAGCAGGTAC
TTCATCACCTAAAACTGAAGGCAAGCACGAAGAAACTGTTAATAAAGAATCGGATATGAAGGTGCCAACTGTAAGTTTGAAAGTATCTGA
AAGTGTAATTGATGTGAAAACAACTATGGAAAGTATATCTAATACGTCTACGCAGTCTCTCACAGCAGAAACAAAGGACATAGCTTTGGA
ACCTAAGGAACAAAAACATGAAGACAGGCAGAGCAATACACCTTCTCCTCCTGTTAGTACCTTTTCATCAGGTACTTCTACCACCAGTGA
TATTGAAGTTTTAGATCATGAAAGTGTAATAAGTGAGAGCTCAGCGAGCTCGAGACAAGAGACTACAGATTCAAAATCAAGTCTTCACTT
GATGCAGACATCTTTTCAGCTTCTCTCTGCATCTGCTTGTCCTGAATATAATCGTTTAGATGATTTCCAAAAACTCACTGAGAGTTGCTG
TTCATCTGATGCTTTTGAAAGAATAGACTCATTTAGTGTACAGTCATTAGATAGCCGGAGTGTAAGTGAAATCAATTCAGATGATGAATT
GTCAGGCAAGGGATATGCTTTAGTGCCTATTATAGTTAATTCTTCAACTCCAAAGTCTAAAACAGTTGAATCTGCTGAAGGAAAATCTGA
AGAAGTAAATGAAACATTAGTTATACCCACTGAGGAAGCAGAAATGGAAGAAAGTGGACGAAGTGCAACTCCTGTTAACTGTGAACAGCC
TGATATCTTGGTTTCTTCCACACCAATAAATGAAGGACAGACTGTGTTAGACAAGGTGGCTGAGCAGTGTGAACCTGCTGAAAGTCAGCC
AGAAGCACTTTCTGAGAAGGAAGATGTTTGCAAGACAGTTGAATTTCTGAATGAAAAGCTGGAAAAAAGGGAGGCTCAGTTATTATCTCT
TAGTAAGGAAAAAGCACTTCTAGAAGAAGCTTTTGATAACCTGAAAGATGAAATGTTCAGAGTGAAAGAAGAAAGCAGTAGCATTTCTTC
CTTGAAAGATGAGTTTACTCAAAGAATTGCAGAAGCAGAAAAGAAAGTTCAACTAGCCTGCAAAGAGAGAGATGCTGCTAAAAAGGAAAT
CAAAAACATAAAAGAAGAACTTGCCACTAGATTAAATAGTAGTGAAACTGCAGACCTTTTGAAAGAGAAAGATGAGCAGATCCGAGGGTT
AATGGAAGAAGGAGAAAAACTTTCAAAACAGCAGCTGCACAATTCTAACATCATCAAGAAATTAAGAGCTAAAGACAAGGAGAATGAAAA
TATGGTTGCAAAGCTGAACAAAAAAGTTAAAGAGCTAGAAGAGGAGTTGCAGCATTTGAAACAGGTCCTTGATGGCAAAGAAGAGGTTGA
GAAACAACATAGAGAAAATATTAAAAAACTAAATTCCATGGTAGAACGCCAAGAGAAAGATCTTGGCCGTCTTCAGGTAGACATGGATGA
ACTTGAAGAAAAGAACCGAAGTATTCAGGCTGCCCTGGATAGTGCATACAAAGAACTTACTGATCTTCACAAAGCCAATGCTGCAAAGGA
TAGTGAGGCACAGGAAGCTGCTCTGAGCCGTGAAATGAAAGCTAAAGAAGAACTTTCTGCAGCATTAGAGAAGGCCCAAGAAGAAGCCCG
TCAGCAGCAAGAAACATTAGCCATTCAAGTGGGGGACCTTAGGCTTGCATTGCAGCGTACAGAACAAGCGGCTGCCAGAAAGGAGGATTA
TTTACGCCATGAGATCGGTGAACTTCAGCAGAGACTCCAGGAAGCAGAGAATCGAAACCAGGAACTGAGTCAAAGTGTTTCATCAACAAC
AAGACCATTGCTTCGACAAATAGAAAATTTGCAAGCAACCCTGGGATCCCAGACATCGTCGTGGGAGAAATTAGAGAAGAATCTTTCTGA
TAGGCTTGGTGAATCCCAGACCTTGCTGGCAGCAGCAGTTGAGAGAGAACGTGCAGCTACAGAAGAACTCCTTGCTAACAAAATTCAGAT
GTCTTCCATGGAGTCACAGAATTCTCTTTTAAGACAGGAAAACAGTAGATTTCAAGCCCAGCTAGAATCAGAGAAAAATAGGCTGTGTAA
ACTGGAGGATGAGAACAATAGGTACCAGGTTGAATTGGAAAACCTAAAAGATGAATATGTAAGAACACTTGAAGAGACGAGGAAAGAAAA
GATGACAGAAGGCAGGCACTGCCAGGTGCACCTCCTGGATGATAGGAGACTGGAGCTGCTGGTTCAGCCCAAACTTCTAGCAAGAGAGTT
GCTGGACCTAGTGGCTTCACATTTCAACCTGAAAGAAAAGGAGTATTTTGGAATAACATTCATAGATGACACAGGTCAGCAGAACTGGCT
GCAGTTAGATCACCGAGTTCTTGACCACGATTTGCCCAAGAAACCAGGCCCAACCATTTTGCACTTTGCTGTGAGGTTTTACATTGAGAG
CATATCGTTTTTAAAGGATAAAACCACCGTGGAGCTGTTTTTCCTGAATGCAAAGGCCTGTGTGCACAAGGGGCAAATCGAAGTAGAGAG
CGAAACCATCTTCAAGTTAGCAGCGTTTATTTTACAGGAAGCCAAGGGAGATTATACCAGTGATGAAAATGCCAGGAAAGATTTAAAGAC
ATTACCAGCCTTTCCAACCAAAACTCTTCAGGAGCATCCATCCCTTGCCTACTGTGAGGACAGGGTAATTGAGCATTATTTGAAAATCAA
AGGTCTCACTCGAGGTCAAGCTGTGGTTCAGTATATGAAAATAGTAGAAGCTCTACCGACTTACGGTGTCCATTATTATGCAGTAAAGGA
TAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTATAAGGGAATTGGCCAATATGATATACAAGACAAGGTGAAGCCTCGGAAGTTATT
CCAATGGAAACAGCTGGAGAACTTATATTTCCGTGAGAAAAAATTTGCTGTTGAAGTTCATGATCCACGAAGGATTTCAGTTTCAAGAAG
AACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATGGTATGCTAACTCTTCTCTCATCAAGTCCATTTGGGTAATGGCAATTAGTCAGCA
TCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAAAATTCCTTCAGCCAGGAGTTTAGATGAGATTGCAATGGATTTGACAGAGACAGG
AACACAAAGGGCCTCCAAGCTGGTGACACTGGAGACGAAAAGTCAGTTCATCATGGCAAGTAATGGCAGTTTAATCTCCTCAGGTTCTCA
AGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAAAATCCTTGAACTAAAGAAGAAGGAGAAACTATTACAAGAAAAACTTCTGAAAAA
AGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGCTGAGCTCACAGGCAAAATGCCAAAGGAGTATCCCCTGAACATAGGCGAGAAGCC
TCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAAATTAGATGACAACTTGCTGCCGAGTGAAGAAGATCCTGCTTTGCAAGAACTGGA
GAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGCTGCAAAGAAACTTGCCAATGAGCCAGACCTTTGTAAAACTGTGAAGAAAAAGCG
AAAGCAAGATTACACAGATGCGATGAAAAAGCTTCAGGAGATTGAAAATGCAATAAACGAATACCGAATTAGGTGTGGAAAGAAACCCAG
CCAGAAAGCAACAGTGTTACCAGAAGACATAATCCCCTCAGAGAGTAGCTCTTTGTCTGACACCACCACCTATGATGATCCCAGTGATGC
CTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACCTCATTCTCCAAGAATTCTTCCCCCCAAGTCTCTTGGTATTGAGCGAATCCATTT
CAGAAAGTCGTCCATCAATGAACAGTTTGTGGATACCAGGCAGTCCAGAGAAATGCTGTCCACACACAGCAGCCCTTACAAAACTCTGGA
GAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCACGCCAGTTCTTACCCGAAACGCCTACAGCAGCAGCCACTTGGAACCCGAATCTTC
ATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGAGTCCCAGTCCCACCTGCTCTCCGAGATGGACAGCGATAAGCCATTTTTCTCCCT
CTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCTCGATGACGGGTCTTCTTATACAAGCCAATCAAGCACAGAGTATTACTGTGTGAC
ACCAGTTACCGGCCCCTATTACACCACCCAGACCCTGGACACTCGCACCAGGGGTCGGAGGAGGTCAAAGAAACAGAATGTTTCTACTTC
AAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGATAGTTTGAGGAATGGTGTTTACTCAAAGAGTCAGGAGCCACCGTCTTCCAGTTA
CTACATTGCCGGGTACACACCCTATGCAGAGTGTGACTTTTATTACAGTGGTGGTTATGTCTATGAGAATGACACCGAGGGACAGTATAG
TGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGGATATGAGCGCCAGAGGGACTACAGCAGATCCTTTCACGAAGATGAGGTCGACCG
GGTACCCCATAACCCATATGCAACTCTCCGGCTGCCAAGGAAGGCTGCTGCAAAATCGGAGCACATCACCAAAAACATCCACAAGGCCTT
AGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGCCTCTGGGCAGAAGGATCAGGGACACAGCCCGCAGACCAGCTTTGACTCAGACAG
GGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCAAGTACCTTGTTCTCCAAGCAGTCGTGCATCCTCGTACTCTTCAGTGTCTTCTAC
AAATGCTTCTGGGAACTGGAGGACCCAGTTAACCATAGGGCTGTCGGATTACGAGACTCCAGCACATTCTTCTTACACCAGCTGCTATGG
CAATGTCTATAATCCTTTACCCTCTCCAAGCAGACAATACACAGAAATCAGTCAACTGGATGGTACAGATGGAAACCAGCTGGAAGACAA
CCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGAAGATTCAAAGCCTGGAACATTAGTCTGAACTGCAGTTGGACCTCCTGACCAAGC
ACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTATTTGTCTTCCGAGAGGATGTTCGTTTTAGAAACCTAAAGACATCAAAGGTTGAA
GAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAATCACACACCAAGCCCCACAAAGCCCCTAAAGGAGGATTTGGCCTTTCAAACTCT
AGGCACTAACGTAACTGTAGGGTCTGCCCACATGTTGAAGTATTGCCAAGAGAGGACTCAGTGTGAAGCCTTCATCAATAGCAAGCACTT
TTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAAAAACATGAAAGGGCATTCAGGATGTCCCATGGCAATAAGAACAGGGGAAATCTC
AGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCAGAAGCTCCGGAGTCATTGCTCACTTCAGAGTTTGAATTCGTGAGCTGACAAAGA
GTAACATGCTCTTTCTACACAGACATGGACAATTTAGACAGTATTGGAAAATTACTTGAAGCTGGATTTTCATGAAGTTCTGAATGAGTG
TAAATGTTTTTTAGGATACTATAAAGAGTGATGTTTTTCATAAGCACCATAAAATGGGTTCTGGAAAAACTGATTACCTTAGCATCCTGT
AATATAACTTATGGTAGCAGATTGGGGAAAATGAAGCAGCCCACTGAATAATTGACAAAGTCTGCTTGGAGAACATTCTAAGGTACAATA
TCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCGTGATGAGCTATTGTTCTGGCTGTTAATTCTCCAACTCGGCTGTCATTTGAAGTG
GCAGACTTAATATGGAAAGTTTTTATAATTATGAGTTTGAAAAAGCATTTTAAGATGATACAGAAAGTATCCAAAACAACAGAAAAAAAA
AGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAATGGTGAACGTTAGAAAATTAAACAAGTCTGGATTCCACAAGTAGTTCCAAGTCA
CCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAAAAACAACAACAACGACAAAAAGCTCCAAGCTGCAGTGGATTTAATTATGAGGCT
AAAACTACCTCATACTTTCCTTGGAAGAACTAATTAGCTATGGTTTATTGTAGGGTTTTGTTTGTTTGTTTTTTAAAGCAAATGATTTCC
ATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTCAAAATTACATAAAAGGTGCTCCTTTCCCCCTTCTTTTATACAAGTTTCTTGTTC
ATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTTGGAACATTTTCTATCTATATTCCAAAGCATGTAATATATACATAAAAACGATTT
GTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAATGAAGTTTGGGAAAAAATTTTGGAAAAAAGACAAGCAAAAAAAAATAACTTATT
CCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAGAAATAACCTTTTTGCATATTCTTTTATTGTTCTGACTTTTCAAGACCTATTATT
TTTTTACATAGGTCAATAAACAAAAGGTGTGCTACTGAAAATGTTTACGTTTTCTTCCATTTATGTCAGGGGTTCATGTGAAGCAGGTCG
CAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGCTTCGGATTTTTATTTATAGTATTACCGTATTTTATTAATTCCGGGATGTACATT
TTTAAATATTTACATTAAAAACATGGTTCATCTTTTTATTGATGGCATATTCTACTTGAATTGGCAGTTTTTTCTTAATAGTACATTAAA

>92306_92306_5_TMF1-FRMD4B_TMF1_chr3_69077377_ENST00000398559_FRMD4B_chr3_69362668_ENST00000398540_length(amino acids)=1868AA_BP=888
MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTSTWGLKSNTEPQSPPIASPKAITKPVRRTVV
DESENFFSAFLSPTDVQTIQKSPVVSKPPAKSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEET
VNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSNTPSPPVSTFSSGTSTTSDIEVLDHESVISE
SSASSRQETTDSKSSLHLMQTSFQLLSASACPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIV
NSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKT
VEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELATRLN
SSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNS
MVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGD
LRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSDRLGESQTLLAAA
VERERAATEELLANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKMTEGRHCQVHLL
DDRRLELLVQPKLLARELLDLVASHFNLKEKEYFGITFIDDTGQQNWLQLDHRVLDHDLPKKPGPTILHFAVRFYIESISFLKDKTTVEL
FFLNAKACVHKGQIEVESETIFKLAAFILQEAKGDYTSDENARKDLKTLPAFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYM
KIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTW
YANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQFIMASNGSLISSGSQDSEVSEEQKREK
ILELKKKEKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQKLVEA
AKKLANEPDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESSSLSDTTTYDDPSDAFTFPGQRSSSVP
HSPRILPPKSLGIERIHFRKSSINEQFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPESSSQHCRQRSGSLE
SQSHLLSEMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRTRGRRRSKKQNVSTSNSGSMPNLAQKD
SLRNGVYSKSQEPPSSSYYIAGYTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQRDYSRSFHEDEVDRVPHNPYATLRLP
RKAAAKSEHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQLTI

--------------------------------------------------------------
>92306_92306_6_TMF1-FRMD4B_TMF1_chr3_69077377_ENST00000398559_FRMD4B_chr3_69362668_ENST00000542259_length(transcript)=7690nt_BP=2881nt
GCAAGCGCATGCGCACATGGGCCCCCTTCGTCTCAGCTGTGCGGGAACGGCCGAGGGTAACATCCCGGGCTCGCGGGAGGCTGTCGGGGT
AATGGCCACACGCTGACAGAACCAGCCGAGTGGAAAAGGGGAGCGAAGCCGTTCCTCTGCACCCTTCCCCAGGCCTGAGGCCTTCCCGCT
TGGTGCTGCCGCCGCCACTGCCGGCTGAGGAGGGGCGATGAGTTGGTTCAACGCCTCCCAGCTCTCCAGCTTCGCTAAGCAGGCCCTGTC
CCAGGCCCAGAAGTCTATTGACAGGGTTCTGGACATCCAGGAAGAGGAGCCGAGCATCTGGGCCGAGACCATTCCGTATGGAGAGCCGGG
AATAAGTTCCCCTGTCAGTGGAGGATGGGATACTTCAACCTGGGGGTTGAAATCAAACACTGAACCTCAGAGTCCACCAATAGCCTCTCC
TAAAGCAATCACAAAGCCAGTTCGGAGGACTGTGGTCGATGAATCTGAAAATTTCTTCAGTGCCTTTCTCTCGCCAACTGATGTCCAGAC
CATTCAGAAGAGTCCAGTGGTATCAAAACCTCCAGCAAAATCACAACGACCAGAAGAAGAAGTGAAAAGCAGCTTACATGAATCCTTGCA
CATTGGCCAGTCAAGAACTCCTGAAACAACTGAATCACAAGTAAAAGACTCTTCTTTGTGTGTTTCAGGGGAAACTCTGGCAGCAGGTAC
TTCATCACCTAAAACTGAAGGCAAGCACGAAGAAACTGTTAATAAAGAATCGGATATGAAGGTGCCAACTGTAAGTTTGAAAGTATCTGA
AAGTGTAATTGATGTGAAAACAACTATGGAAAGTATATCTAATACGTCTACGCAGTCTCTCACAGCAGAAACAAAGGACATAGCTTTGGA
ACCTAAGGAACAAAAACATGAAGACAGGCAGAGCAATACACCTTCTCCTCCTGTTAGTACCTTTTCATCAGGTACTTCTACCACCAGTGA
TATTGAAGTTTTAGATCATGAAAGTGTAATAAGTGAGAGCTCAGCGAGCTCGAGACAAGAGACTACAGATTCAAAATCAAGTCTTCACTT
GATGCAGACATCTTTTCAGCTTCTCTCTGCATCTGCTTGTCCTGAATATAATCGTTTAGATGATTTCCAAAAACTCACTGAGAGTTGCTG
TTCATCTGATGCTTTTGAAAGAATAGACTCATTTAGTGTACAGTCATTAGATAGCCGGAGTGTAAGTGAAATCAATTCAGATGATGAATT
GTCAGGCAAGGGATATGCTTTAGTGCCTATTATAGTTAATTCTTCAACTCCAAAGTCTAAAACAGTTGAATCTGCTGAAGGAAAATCTGA
AGAAGTAAATGAAACATTAGTTATACCCACTGAGGAAGCAGAAATGGAAGAAAGTGGACGAAGTGCAACTCCTGTTAACTGTGAACAGCC
TGATATCTTGGTTTCTTCCACACCAATAAATGAAGGACAGACTGTGTTAGACAAGGTGGCTGAGCAGTGTGAACCTGCTGAAAGTCAGCC
AGAAGCACTTTCTGAGAAGGAAGATGTTTGCAAGACAGTTGAATTTCTGAATGAAAAGCTGGAAAAAAGGGAGGCTCAGTTATTATCTCT
TAGTAAGGAAAAAGCACTTCTAGAAGAAGCTTTTGATAACCTGAAAGATGAAATGTTCAGAGTGAAAGAAGAAAGCAGTAGCATTTCTTC
CTTGAAAGATGAGTTTACTCAAAGAATTGCAGAAGCAGAAAAGAAAGTTCAACTAGCCTGCAAAGAGAGAGATGCTGCTAAAAAGGAAAT
CAAAAACATAAAAGAAGAACTTGCCACTAGATTAAATAGTAGTGAAACTGCAGACCTTTTGAAAGAGAAAGATGAGCAGATCCGAGGGTT
AATGGAAGAAGGAGAAAAACTTTCAAAACAGCAGCTGCACAATTCTAACATCATCAAGAAATTAAGAGCTAAAGACAAGGAGAATGAAAA
TATGGTTGCAAAGCTGAACAAAAAAGTTAAAGAGCTAGAAGAGGAGTTGCAGCATTTGAAACAGGTCCTTGATGGCAAAGAAGAGGTTGA
GAAACAACATAGAGAAAATATTAAAAAACTAAATTCCATGGTAGAACGCCAAGAGAAAGATCTTGGCCGTCTTCAGGTAGACATGGATGA
ACTTGAAGAAAAGAACCGAAGTATTCAGGCTGCCCTGGATAGTGCATACAAAGAACTTACTGATCTTCACAAAGCCAATGCTGCAAAGGA
TAGTGAGGCACAGGAAGCTGCTCTGAGCCGTGAAATGAAAGCTAAAGAAGAACTTTCTGCAGCATTAGAGAAGGCCCAAGAAGAAGCCCG
TCAGCAGCAAGAAACATTAGCCATTCAAGTGGGGGACCTTAGGCTTGCATTGCAGCGTACAGAACAAGCGGCTGCCAGAAAGGAGGATTA
TTTACGCCATGAGATCGGTGAACTTCAGCAGAGACTCCAGGAAGCAGAGAATCGAAACCAGGAACTGAGTCAAAGTGTTTCATCAACAAC
AAGACCATTGCTTCGACAAATAGAAAATTTGCAAGCAACCCTGGGATCCCAGACATCGTCGTGGGAGAAATTAGAGAAGAATCTTTCTGA
TAGGCTTGGTGAATCCCAGACCTTGCTGGCAGCAGCAGTTGAGAGAGAACGTGCAGCTACAGAAGAACTCCTTGCTAACAAAATTCAGAT
GTCTTCCATGGAGTCACAGAATTCTCTTTTAAGACAGGAAAACAGTAGATTTCAAGCCCAGCTAGAATCAGAGAAAAATAGGCTGTGTAA
ACTGGAGGATGAGAACAATAGGTACCAGGTTGAATTGGAAAACCTAAAAGATGAATATGTAAGAACACTTGAAGAGACGAGGAAAGAAAA
GATGACAGAAGGCAGGCACTGCCAGGTGCACCTCCTGGATGATAGGAGACTGGAGCTGCTGGTTCAGCCCAAACTTCTAGCAAGAGAGTT
GCTGGACCTAGTGGCTTCACATTTCAACCTGAAAGAAAAGGAGTATTTTGGAATAACATTCATAGATGACACAGGTCAGCAGAACTGGCT
GCAGTTAGATCACCGAGTTCTTGACCACGATTTGCCCAAGAAACCAGGCCCAACCATTTTGCACTTTGCTGTGAGGTTTTACATTGAGAG
CATATCGTTTTTAAAGGATAAAACCACCGTGGAGCTGTTTTTCCTGAATGCAAAGGCCTGTGTGCACAAGGGGCAAATCGAAGTAGAGAG
CGAAACCATCTTCAAGTTAGCAGCGTTTATTTTACAGTCTCCCAAAGTCTCGCTTACCCATGATGAAAATGCCAGGAAAGATTTAAAGAC
ATTACCAGCCTTTCCAACCAAAACTCTTCAGGAGCATCCATCCCTTGCCTACTGTGAGGACAGGGTAATTGAGCATTATTTGAAAATCAA
AGGTCTCACTCGAGGTCAAGCTGTGGTTCAGTATATGAAAATAGTAGAAGCTCTACCGACTTACGGTGTCCATTATTATGCAGTAAAGGA
TAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTATAAGGGAATTGGCCAATATGATATACAAGACAAGGTGAAGCCTCGGAAGTTATT
CCAATGGAAACAGCTGGAGAACTTATATTTCCGTGAGAAAAAATTTGCTGTTGAAGTTCATGATCCACGAAGGATTTCAGTTTCAAGAAG
AACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATGGTATGCTAACTCTTCTCTCATCAAGTCCATTTGGGTAATGGCAATTAGTCAGCA
TCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAAAATTCCTTCAGCCAGGAGTTTAGATGAGATTGCAATGGATTTGACAGAGACAGG
AACACAAAGGGCCTCCAAGCTGGTGACACTGGAGACGAAAAGTCAGTTCATCATGGCAAGTAATGGCAGTTTAATCTCCTCAGGTTCTCA
AGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAAAATCCTTGAACTAAAGAAGAAGGAGAAACTATTACAAGAAAAACTTCTGAAAAA
AGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGCTGAGCTCACAGGCAAAATGCCAAAGGAGTATCCCCTGAACATAGGCGAGAAGCC
TCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAAATTAGATGACAACTTGCTGCCGAGTGAAGAAGATCCTGCTTTGCAAGAACTGGA
GAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGCTGCAAAGAAACTTGCCAATGAGCCAGACCTTTGTAAAACTGTGAAGAAAAAGCG
AAAGCAAGATTACACAGATGCGATGAAAAAGCTTCAGGAGATTGAAAATGCAATAAACGAATACCGAATTAGGTGTGGAAAGAAACCCAG
CCAGAAAGCAACAGTGTTACCAGAAGACATAATCCCCTCAGAGAGTAGCTCTTTGTCTGACACCACCACCTATGATGATCCCAGTGATGC
CTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACCTCATTCTCCAAGAATTCTTCCCCCCAAGTCTCTTGGTATTGAGCGAATCCATTT
CAGAAAGTCGTCCATCAATGAACAGTTTGTGGATACCAGGCAGTCCAGAGAAATGCTGTCCACACACAGCAGCCCTTACAAAACTCTGGA
GAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCACGCCAGTTCTTACCCGAAACGCCTACAGCAGCAGCCACTTGGAACCCGAATCTTC
ATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGAGTCCCAGTCCCACCTGCTCTCCGAGATGGACAGCGATAAGCCATTTTTCTCCCT
CTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCTCGATGACGGGTCTTCTTATACAAGCCAATCAAGCACAGAGTATTACTGTGTGAC
ACCAGTTACCGGCCCCTATTACACCACCCAGACCCTGGACACTCGCACCAGGGGTCGGAGGAGGTCAAAGAAACAGAATGTTTCTACTTC
AAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGATAGTTTGAGGAATGGTGTTTACTCAAAGAGTCAGGAGCCACCGTCTTCCAGTTA
CTACATTGCCGGGTACACACCCTATGCAGAGTGTGACTTTTATTACAGTGGTGGTTATGTCTATGAGAATGACACCGAGGGACAGTATAG
TGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGGATATGAGCGCCAGAGGGACTACAGCAGATCCTTTCACGAAGATGAGGTCGACCG
GGTACCCCATAACCCATATGCAACTCTCCGGCTGCCAAGGAAGGCTGCTGCAAAATCGGAGCACATCACCAAAAACATCCACAAGGCCTT
AGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGCCTCTGGGCAGAAGGATCAGGGACACAGCCCGCAGACCAGCTTTGACTCAGACAG
GGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCAAGTACCTTGTTCTCCAAGCAGTCGTGCATCCTCGTACTCTTCAGTGTCTTCTAC
AAATGCTTCTGGGAACTGGAGGACCCAGTTAACCATAGGGCTGTCGGATTACGAGACTCCAGCACATTCTTCTTACACCAGCTGCTATGG
CAATGTCTATAATCCTTTACCCTCTCCAAGCAGACAATACACAGAAATCAGTCAACTGGATGGTACAGATGGAAACCAGCTGGAAGACAA
CCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGAAGATTCAAAGCCTGGAACATTAGTCTGAACTGCAGTTGGACCTCCTGACCAAGC
ACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTATTTGTCTTCCGAGAGGATGTTCGTTTTAGAAACCTAAAGACATCAAAGGTTGAA
GAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAATCACACACCAAGCCCCACAAAGCCCCTAAAGGAGGATTTGGCCTTTCAAACTCT
AGGCACTAACGTAACTGTAGGGTCTGCCCACATGTTGAAGTATTGCCAAGAGAGGACTCAGTGTGAAGCCTTCATCAATAGCAAGCACTT
TTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAAAAACATGAAAGGGCATTCAGGATGTCCCATGGCAATAAGAACAGGGGAAATCTC
AGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCAGAAGCTCCGGAGTCATTGCTCACTTCAGAGTTTGAATTCGTGAGCTGACAAAGA
GTAACATGCTCTTTCTACACAGACATGGACAATTTAGACAGTATTGGAAAATTACTTGAAGCTGGATTTTCATGAAGTTCTGAATGAGTG
TAAATGTTTTTTAGGATACTATAAAGAGTGATGTTTTTCATAAGCACCATAAAATGGGTTCTGGAAAAACTGATTACCTTAGCATCCTGT
AATATAACTTATGGTAGCAGATTGGGGAAAATGAAGCAGCCCACTGAATAATTGACAAAGTCTGCTTGGAGAACATTCTAAGGTACAATA
TCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCGTGATGAGCTATTGTTCTGGCTGTTAATTCTCCAACTCGGCTGTCATTTGAAGTG
GCAGACTTAATATGGAAAGTTTTTATAATTATGAGTTTGAAAAAGCATTTTAAGATGATACAGAAAGTATCCAAAACAACAGAAAAAAAA
AGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAATGGTGAACGTTAGAAAATTAAACAAGTCTGGATTCCACAAGTAGTTCCAAGTCA
CCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAAAAACAACAACAACGACAAAAAGCTCCAAGCTGCAGTGGATTTAATTATGAGGCT
AAAACTACCTCATACTTTCCTTGGAAGAACTAATTAGCTATGGTTTATTGTAGGGTTTTGTTTGTTTGTTTTTTAAAGCAAATGATTTCC
ATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTCAAAATTACATAAAAGGTGCTCCTTTCCCCCTTCTTTTATACAAGTTTCTTGTTC
ATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTTGGAACATTTTCTATCTATATTCCAAAGCATGTAATATATACATAAAAACGATTT
GTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAATGAAGTTTGGGAAAAAATTTTGGAAAAAAGACAAGCAAAAAAAAATAACTTATT
CCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAGAAATAACCTTTTTGCATATTCTTTTATTGTTCTGACTTTTCAAGACCTATTATT
TTTTTACATAGGTCAATAAACAAAAGGTGTGCTACTGAAAATGTTTACGTTTTCTTCCATTTATGTCAGGGGTTCATGTGAAGCAGGTCG
CAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGCTTCGGATTTTTATTTATAGTATTACCGTATTTTATTAATTCCGGGATGTACATT
TTTAAATATTTACATTAAAAACATGGTTCATCTTTTTATTGATGGCATATTCTACTTGAATTGGCAGTTTTTTCTTAATAGTACATTAAA

>92306_92306_6_TMF1-FRMD4B_TMF1_chr3_69077377_ENST00000398559_FRMD4B_chr3_69362668_ENST00000542259_length(amino acids)=1868AA_BP=888
MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTSTWGLKSNTEPQSPPIASPKAITKPVRRTVV
DESENFFSAFLSPTDVQTIQKSPVVSKPPAKSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEET
VNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSNTPSPPVSTFSSGTSTTSDIEVLDHESVISE
SSASSRQETTDSKSSLHLMQTSFQLLSASACPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIV
NSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKT
VEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELATRLN
SSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNS
MVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGD
LRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSDRLGESQTLLAAA
VERERAATEELLANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKMTEGRHCQVHLL
DDRRLELLVQPKLLARELLDLVASHFNLKEKEYFGITFIDDTGQQNWLQLDHRVLDHDLPKKPGPTILHFAVRFYIESISFLKDKTTVEL
FFLNAKACVHKGQIEVESETIFKLAAFILQSPKVSLTHDENARKDLKTLPAFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYM
KIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTW
YANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQFIMASNGSLISSGSQDSEVSEEQKREK
ILELKKKEKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQKLVEA
AKKLANEPDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESSSLSDTTTYDDPSDAFTFPGQRSSSVP
HSPRILPPKSLGIERIHFRKSSINEQFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPESSSQHCRQRSGSLE
SQSHLLSEMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRTRGRRRSKKQNVSTSNSGSMPNLAQKD
SLRNGVYSKSQEPPSSSYYIAGYTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQRDYSRSFHEDEVDRVPHNPYATLRLP
RKAAAKSEHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQLTI

--------------------------------------------------------------
>92306_92306_7_TMF1-FRMD4B_TMF1_chr3_69077377_ENST00000543976_FRMD4B_chr3_69362668_ENST00000398540_length(transcript)=7734nt_BP=2920nt
GTAGATTTGGTTGCTGTGTACGTGGAAGAAGCAAGCGCATGCGCACATGGGCCCCCTTCGTCTCAGCTGTGCGGGAACGGCCGAGGGTAA
CATCCCGGGCTCGCGGGAGGCTGTCGGGGTAATGGCCACACGCTGACAGAACCAGCCGAGTGGAAAAGGGGAGCGAAGCCGTTCCTCTGC
ACCCTTCCCCAGGCCTGAGGCCTTCCCGCTTGGTGCTGCCGCCGCCACTGCCGGCTGAGGAGGGGCGATGAGTTGGTTCAACGCCTCCCA
GCTCTCCAGCTTCGCTAAGCAGGCCCTGTCCCAGGCCCAGAAGTCTATTGACAGGGTTCTGGACATCCAGGAAGAGGAGCCGAGCATCTG
GGCCGAGACCATTCCGTATGGAGAGCCGGGAATAAGTTCCCCTGTCAGTGGAGGATGGGATACTTCAACCTGGGGGTTGAAATCAAACAC
TGAACCTCAGAGTCCACCAATAGCCTCTCCTAAAGCAATCACAAAGCCAGTTCGGAGGACTGTGGTCGATGAATCTGAAAATTTCTTCAG
TGCCTTTCTCTCGCCAACTGATGTCCAGACCATTCAGAAGAGTCCAGTGGTATCAAAACCTCCAGCAAAATCACAACGACCAGAAGAAGA
AGTGAAAAGCAGCTTACATGAATCCTTGCACATTGGCCAGTCAAGAACTCCTGAAACAACTGAATCACAAGTAAAAGACTCTTCTTTGTG
TGTTTCAGGGGAAACTCTGGCAGCAGGTACTTCATCACCTAAAACTGAAGGCAAGCACGAAGAAACTGTTAATAAAGAATCGGATATGAA
GGTGCCAACTGTAAGTTTGAAAGTATCTGAAAGTGTAATTGATGTGAAAACAACTATGGAAAGTATATCTAATACGTCTACGCAGTCTCT
CACAGCAGAAACAAAGGACATAGCTTTGGAACCTAAGGAACAAAAACATGAAGACAGGCAGAGCAATACACCTTCTCCTCCTGTTAGTAC
CTTTTCATCAGGTACTTCTACCACCAGTGATATTGAAGTTTTAGATCATGAAAGTGTAATAAGTGAGAGCTCAGCGAGCTCGAGACAAGA
GACTACAGATTCAAAATCAAGTCTTCACTTGATGCAGACATCTTTTCAGCTTCTCTCTGCATCTGCTTGTCCTGAATATAATCGTTTAGA
TGATTTCCAAAAACTCACTGAGAGTTGCTGTTCATCTGATGCTTTTGAAAGAATAGACTCATTTAGTGTACAGTCATTAGATAGCCGGAG
TGTAAGTGAAATCAATTCAGATGATGAATTGTCAGGCAAGGGATATGCTTTAGTGCCTATTATAGTTAATTCTTCAACTCCAAAGTCTAA
AACAGTTGAATCTGCTGAAGGAAAATCTGAAGAAGTAAATGAAACATTAGTTATACCCACTGAGGAAGCAGAAATGGAAGAAAGTGGACG
AAGTGCAACTCCTGTTAACTGTGAACAGCCTGATATCTTGGTTTCTTCCACACCAATAAATGAAGGACAGACTGTGTTAGACAAGGTGGC
TGAGCAGTGTGAACCTGCTGAAAGTCAGCCAGAAGCACTTTCTGAGAAGGAAGATGTTTGCAAGGTAACTCTAACAGTTGAATTTCTGAA
TGAAAAGCTGGAAAAAAGGGAGGCTCAGTTATTATCTCTTAGTAAGGAAAAAGCACTTCTAGAAGAAGCTTTTGATAACCTGAAAGATGA
AATGTTCAGAGTGAAAGAAGAAAGCAGTAGCATTTCTTCCTTGAAAGATGAGTTTACTCAAAGAATTGCAGAAGCAGAAAAGAAAGTTCA
ACTAGCCTGCAAAGAGAGAGATGCTGCTAAAAAGGAAATCAAAAACATAAAAGAAGAACTTGCCACTAGATTAAATAGTAGTGAAACTGC
AGACCTTTTGAAAGAGAAAGATGAGCAGATCCGAGGGTTAATGGAAGAAGGAGAAAAACTTTCAAAACAGCAGCTGCACAATTCTAACAT
CATCAAGAAATTAAGAGCTAAAGACAAGGAGAATGAAAATATGGTTGCAAAGCTGAACAAAAAAGTTAAAGAGCTAGAAGAGGAGTTGCA
GCATTTGAAACAGGTCCTTGATGGCAAAGAAGAGGTTGAGAAACAACATAGAGAAAATATTAAAAAACTAAATTCCATGGTAGAACGCCA
AGAGAAAGATCTTGGCCGTCTTCAGGTAGACATGGATGAACTTGAAGAAAAGAACCGAAGTATTCAGGCTGCCCTGGATAGTGCATACAA
AGAACTTACTGATCTTCACAAAGCCAATGCTGCAAAGGATAGTGAGGCACAGGAAGCTGCTCTGAGCCGTGAAATGAAAGCTAAAGAAGA
ACTTTCTGCAGCATTAGAGAAGGCCCAAGAAGAAGCCCGTCAGCAGCAAGAAACATTAGCCATTCAAGTGGGGGACCTTAGGCTTGCATT
GCAGCGTACAGAACAAGCGGCTGCCAGAAAGGAGGATTATTTACGCCATGAGATCGGTGAACTTCAGCAGAGACTCCAGGAAGCAGAGAA
TCGAAACCAGGAACTGAGTCAAAGTGTTTCATCAACAACAAGACCATTGCTTCGACAAATAGAAAATTTGCAAGCAACCCTGGGATCCCA
GACATCGTCGTGGGAGAAATTAGAGAAGAATCTTTCTGATAGGCTTGGTGAATCCCAGACCTTGCTGGCAGCAGCAGTTGAGAGAGAACG
TGCAGCTACAGAAGAACTCCTTGCTAACAAAATTCAGATGTCTTCCATGGAGTCACAGAATTCTCTTTTAAGACAGGAAAACAGTAGATT
TCAAGCCCAGCTAGAATCAGAGAAAAATAGGCTGTGTAAACTGGAGGATGAGAACAATAGGTACCAGGTTGAATTGGAAAACCTAAAAGA
TGAATATGTAAGAACACTTGAAGAGACGAGGAAAGAAAAGATGACAGAAGGCAGGCACTGCCAGGTGCACCTCCTGGATGATAGGAGACT
GGAGCTGCTGGTTCAGCCCAAACTTCTAGCAAGAGAGTTGCTGGACCTAGTGGCTTCACATTTCAACCTGAAAGAAAAGGAGTATTTTGG
AATAACATTCATAGATGACACAGGTCAGCAGAACTGGCTGCAGTTAGATCACCGAGTTCTTGACCACGATTTGCCCAAGAAACCAGGCCC
AACCATTTTGCACTTTGCTGTGAGGTTTTACATTGAGAGCATATCGTTTTTAAAGGATAAAACCACCGTGGAGCTGTTTTTCCTGAATGC
AAAGGCCTGTGTGCACAAGGGGCAAATCGAAGTAGAGAGCGAAACCATCTTCAAGTTAGCAGCGTTTATTTTACAGGAAGCCAAGGGAGA
TTATACCAGTGATGAAAATGCCAGGAAAGATTTAAAGACATTACCAGCCTTTCCAACCAAAACTCTTCAGGAGCATCCATCCCTTGCCTA
CTGTGAGGACAGGGTAATTGAGCATTATTTGAAAATCAAAGGTCTCACTCGAGGTCAAGCTGTGGTTCAGTATATGAAAATAGTAGAAGC
TCTACCGACTTACGGTGTCCATTATTATGCAGTAAAGGATAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTATAAGGGAATTGGCCA
ATATGATATACAAGACAAGGTGAAGCCTCGGAAGTTATTCCAATGGAAACAGCTGGAGAACTTATATTTCCGTGAGAAAAAATTTGCTGT
TGAAGTTCATGATCCACGAAGGATTTCAGTTTCAAGAAGAACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATGGTATGCTAACTCTTC
TCTCATCAAGTCCATTTGGGTAATGGCAATTAGTCAGCATCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAAAATTCCTTCAGCCAG
GAGTTTAGATGAGATTGCAATGGATTTGACAGAGACAGGAACACAAAGGGCCTCCAAGCTGGTGACACTGGAGACGAAAAGTCAGTTCAT
CATGGCAAGTAATGGCAGTTTAATCTCCTCAGGTTCTCAAGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAAAATCCTTGAACTAAA
GAAGAAGGAGAAACTATTACAAGAAAAACTTCTGAAAAAAGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGCTGAGCTCACAGGCAA
AATGCCAAAGGAGTATCCCCTGAACATAGGCGAGAAGCCTCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAAATTAGATGACAACTT
GCTGCCGAGTGAAGAAGATCCTGCTTTGCAAGAACTGGAGAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGCTGCAAAGAAACTTGC
CAATGAGCCAGACCTTTGTAAAACTGTGAAGAAAAAGCGAAAGCAAGATTACACAGATGCGATGAAAAAGCTTCAGGAGATTGAAAATGC
AATAAACGAATACCGAATTAGGTGTGGAAAGAAACCCAGCCAGAAAGCAACAGTGTTACCAGAAGACATAATCCCCTCAGAGAGTAGCTC
TTTGTCTGACACCACCACCTATGATGATCCCAGTGATGCCTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACCTCATTCTCCAAGAAT
TCTTCCCCCCAAGTCTCTTGGTATTGAGCGAATCCATTTCAGAAAGTCGTCCATCAATGAACAGTTTGTGGATACCAGGCAGTCCAGAGA
AATGCTGTCCACACACAGCAGCCCTTACAAAACTCTGGAGAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCACGCCAGTTCTTACCCG
AAACGCCTACAGCAGCAGCCACTTGGAACCCGAATCTTCATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGAGTCCCAGTCCCACCT
GCTCTCCGAGATGGACAGCGATAAGCCATTTTTCTCCCTCTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCTCGATGACGGGTCTTC
TTATACAAGCCAATCAAGCACAGAGTATTACTGTGTGACACCAGTTACCGGCCCCTATTACACCACCCAGACCCTGGACACTCGCACCAG
GGGTCGGAGGAGGTCAAAGAAACAGAATGTTTCTACTTCAAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGATAGTTTGAGGAATGG
TGTTTACTCAAAGAGTCAGGAGCCACCGTCTTCCAGTTACTACATTGCCGGGTACACACCCTATGCAGAGTGTGACTTTTATTACAGTGG
TGGTTATGTCTATGAGAATGACACCGAGGGACAGTATAGTGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGGATATGAGCGCCAGAG
GGACTACAGCAGATCCTTTCACGAAGATGAGGTCGACCGGGTACCCCATAACCCATATGCAACTCTCCGGCTGCCAAGGAAGGCTGCTGC
AAAATCGGAGCACATCACCAAAAACATCCACAAGGCCTTAGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGCCTCTGGGCAGAAGGA
TCAGGGACACAGCCCGCAGACCAGCTTTGACTCAGACAGGGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCAAGTACCTTGTTCTCC
AAGCAGTCGTGCATCCTCGTACTCTTCAGTGTCTTCTACAAATGCTTCTGGGAACTGGAGGACCCAGTTAACCATAGGGCTGTCGGATTA
CGAGACTCCAGCACATTCTTCTTACACCAGCTGCTATGGCAATGTCTATAATCCTTTACCCTCTCCAAGCAGACAATACACAGAAATCAG
TCAACTGGATGGTACAGATGGAAACCAGCTGGAAGACAACCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGAAGATTCAAAGCCTGG
AACATTAGTCTGAACTGCAGTTGGACCTCCTGACCAAGCACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTATTTGTCTTCCGAGAG
GATGTTCGTTTTAGAAACCTAAAGACATCAAAGGTTGAAGAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAATCACACACCAAGCCC
CACAAAGCCCCTAAAGGAGGATTTGGCCTTTCAAACTCTAGGCACTAACGTAACTGTAGGGTCTGCCCACATGTTGAAGTATTGCCAAGA
GAGGACTCAGTGTGAAGCCTTCATCAATAGCAAGCACTTTTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAAAAACATGAAAGGGCA
TTCAGGATGTCCCATGGCAATAAGAACAGGGGAAATCTCAGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCAGAAGCTCCGGAGTCA
TTGCTCACTTCAGAGTTTGAATTCGTGAGCTGACAAAGAGTAACATGCTCTTTCTACACAGACATGGACAATTTAGACAGTATTGGAAAA
TTACTTGAAGCTGGATTTTCATGAAGTTCTGAATGAGTGTAAATGTTTTTTAGGATACTATAAAGAGTGATGTTTTTCATAAGCACCATA
AAATGGGTTCTGGAAAAACTGATTACCTTAGCATCCTGTAATATAACTTATGGTAGCAGATTGGGGAAAATGAAGCAGCCCACTGAATAA
TTGACAAAGTCTGCTTGGAGAACATTCTAAGGTACAATATCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCGTGATGAGCTATTGTT
CTGGCTGTTAATTCTCCAACTCGGCTGTCATTTGAAGTGGCAGACTTAATATGGAAAGTTTTTATAATTATGAGTTTGAAAAAGCATTTT
AAGATGATACAGAAAGTATCCAAAACAACAGAAAAAAAAAGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAATGGTGAACGTTAGAA
AATTAAACAAGTCTGGATTCCACAAGTAGTTCCAAGTCACCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAAAAACAACAACAACGA
CAAAAAGCTCCAAGCTGCAGTGGATTTAATTATGAGGCTAAAACTACCTCATACTTTCCTTGGAAGAACTAATTAGCTATGGTTTATTGT
AGGGTTTTGTTTGTTTGTTTTTTAAAGCAAATGATTTCCATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTCAAAATTACATAAAAG
GTGCTCCTTTCCCCCTTCTTTTATACAAGTTTCTTGTTCATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTTGGAACATTTTCTATC
TATATTCCAAAGCATGTAATATATACATAAAAACGATTTGTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAATGAAGTTTGGGAAAA
AATTTTGGAAAAAAGACAAGCAAAAAAAAATAACTTATTCCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAGAAATAACCTTTTTGC
ATATTCTTTTATTGTTCTGACTTTTCAAGACCTATTATTTTTTTACATAGGTCAATAAACAAAAGGTGTGCTACTGAAAATGTTTACGTT
TTCTTCCATTTATGTCAGGGGTTCATGTGAAGCAGGTCGCAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGCTTCGGATTTTTATTT
ATAGTATTACCGTATTTTATTAATTCCGGGATGTACATTTTTAAATATTTACATTAAAAACATGGTTCATCTTTTTATTGATGGCATATT

>92306_92306_7_TMF1-FRMD4B_TMF1_chr3_69077377_ENST00000543976_FRMD4B_chr3_69362668_ENST00000398540_length(amino acids)=1871AA_BP=891
MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTSTWGLKSNTEPQSPPIASPKAITKPVRRTVV
DESENFFSAFLSPTDVQTIQKSPVVSKPPAKSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEET
VNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSNTPSPPVSTFSSGTSTTSDIEVLDHESVISE
SSASSRQETTDSKSSLHLMQTSFQLLSASACPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIV
NSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKV
TLTVEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELAT
RLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKK
LNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQ
VGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSDRLGESQTLL
AAAVERERAATEELLANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKMTEGRHCQV
HLLDDRRLELLVQPKLLARELLDLVASHFNLKEKEYFGITFIDDTGQQNWLQLDHRVLDHDLPKKPGPTILHFAVRFYIESISFLKDKTT
VELFFLNAKACVHKGQIEVESETIFKLAAFILQEAKGDYTSDENARKDLKTLPAFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVV
QYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFV
QTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQFIMASNGSLISSGSQDSEVSEEQK
REKILELKKKEKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQKL
VEAAKKLANEPDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESSSLSDTTTYDDPSDAFTFPGQRSS
SVPHSPRILPPKSLGIERIHFRKSSINEQFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPESSSQHCRQRSG
SLESQSHLLSEMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRTRGRRRSKKQNVSTSNSGSMPNLA
QKDSLRNGVYSKSQEPPSSSYYIAGYTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQRDYSRSFHEDEVDRVPHNPYATL
RLPRKAAAKSEHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQ

--------------------------------------------------------------
>92306_92306_8_TMF1-FRMD4B_TMF1_chr3_69077377_ENST00000543976_FRMD4B_chr3_69362668_ENST00000542259_length(transcript)=7729nt_BP=2920nt
GTAGATTTGGTTGCTGTGTACGTGGAAGAAGCAAGCGCATGCGCACATGGGCCCCCTTCGTCTCAGCTGTGCGGGAACGGCCGAGGGTAA
CATCCCGGGCTCGCGGGAGGCTGTCGGGGTAATGGCCACACGCTGACAGAACCAGCCGAGTGGAAAAGGGGAGCGAAGCCGTTCCTCTGC
ACCCTTCCCCAGGCCTGAGGCCTTCCCGCTTGGTGCTGCCGCCGCCACTGCCGGCTGAGGAGGGGCGATGAGTTGGTTCAACGCCTCCCA
GCTCTCCAGCTTCGCTAAGCAGGCCCTGTCCCAGGCCCAGAAGTCTATTGACAGGGTTCTGGACATCCAGGAAGAGGAGCCGAGCATCTG
GGCCGAGACCATTCCGTATGGAGAGCCGGGAATAAGTTCCCCTGTCAGTGGAGGATGGGATACTTCAACCTGGGGGTTGAAATCAAACAC
TGAACCTCAGAGTCCACCAATAGCCTCTCCTAAAGCAATCACAAAGCCAGTTCGGAGGACTGTGGTCGATGAATCTGAAAATTTCTTCAG
TGCCTTTCTCTCGCCAACTGATGTCCAGACCATTCAGAAGAGTCCAGTGGTATCAAAACCTCCAGCAAAATCACAACGACCAGAAGAAGA
AGTGAAAAGCAGCTTACATGAATCCTTGCACATTGGCCAGTCAAGAACTCCTGAAACAACTGAATCACAAGTAAAAGACTCTTCTTTGTG
TGTTTCAGGGGAAACTCTGGCAGCAGGTACTTCATCACCTAAAACTGAAGGCAAGCACGAAGAAACTGTTAATAAAGAATCGGATATGAA
GGTGCCAACTGTAAGTTTGAAAGTATCTGAAAGTGTAATTGATGTGAAAACAACTATGGAAAGTATATCTAATACGTCTACGCAGTCTCT
CACAGCAGAAACAAAGGACATAGCTTTGGAACCTAAGGAACAAAAACATGAAGACAGGCAGAGCAATACACCTTCTCCTCCTGTTAGTAC
CTTTTCATCAGGTACTTCTACCACCAGTGATATTGAAGTTTTAGATCATGAAAGTGTAATAAGTGAGAGCTCAGCGAGCTCGAGACAAGA
GACTACAGATTCAAAATCAAGTCTTCACTTGATGCAGACATCTTTTCAGCTTCTCTCTGCATCTGCTTGTCCTGAATATAATCGTTTAGA
TGATTTCCAAAAACTCACTGAGAGTTGCTGTTCATCTGATGCTTTTGAAAGAATAGACTCATTTAGTGTACAGTCATTAGATAGCCGGAG
TGTAAGTGAAATCAATTCAGATGATGAATTGTCAGGCAAGGGATATGCTTTAGTGCCTATTATAGTTAATTCTTCAACTCCAAAGTCTAA
AACAGTTGAATCTGCTGAAGGAAAATCTGAAGAAGTAAATGAAACATTAGTTATACCCACTGAGGAAGCAGAAATGGAAGAAAGTGGACG
AAGTGCAACTCCTGTTAACTGTGAACAGCCTGATATCTTGGTTTCTTCCACACCAATAAATGAAGGACAGACTGTGTTAGACAAGGTGGC
TGAGCAGTGTGAACCTGCTGAAAGTCAGCCAGAAGCACTTTCTGAGAAGGAAGATGTTTGCAAGGTAACTCTAACAGTTGAATTTCTGAA
TGAAAAGCTGGAAAAAAGGGAGGCTCAGTTATTATCTCTTAGTAAGGAAAAAGCACTTCTAGAAGAAGCTTTTGATAACCTGAAAGATGA
AATGTTCAGAGTGAAAGAAGAAAGCAGTAGCATTTCTTCCTTGAAAGATGAGTTTACTCAAAGAATTGCAGAAGCAGAAAAGAAAGTTCA
ACTAGCCTGCAAAGAGAGAGATGCTGCTAAAAAGGAAATCAAAAACATAAAAGAAGAACTTGCCACTAGATTAAATAGTAGTGAAACTGC
AGACCTTTTGAAAGAGAAAGATGAGCAGATCCGAGGGTTAATGGAAGAAGGAGAAAAACTTTCAAAACAGCAGCTGCACAATTCTAACAT
CATCAAGAAATTAAGAGCTAAAGACAAGGAGAATGAAAATATGGTTGCAAAGCTGAACAAAAAAGTTAAAGAGCTAGAAGAGGAGTTGCA
GCATTTGAAACAGGTCCTTGATGGCAAAGAAGAGGTTGAGAAACAACATAGAGAAAATATTAAAAAACTAAATTCCATGGTAGAACGCCA
AGAGAAAGATCTTGGCCGTCTTCAGGTAGACATGGATGAACTTGAAGAAAAGAACCGAAGTATTCAGGCTGCCCTGGATAGTGCATACAA
AGAACTTACTGATCTTCACAAAGCCAATGCTGCAAAGGATAGTGAGGCACAGGAAGCTGCTCTGAGCCGTGAAATGAAAGCTAAAGAAGA
ACTTTCTGCAGCATTAGAGAAGGCCCAAGAAGAAGCCCGTCAGCAGCAAGAAACATTAGCCATTCAAGTGGGGGACCTTAGGCTTGCATT
GCAGCGTACAGAACAAGCGGCTGCCAGAAAGGAGGATTATTTACGCCATGAGATCGGTGAACTTCAGCAGAGACTCCAGGAAGCAGAGAA
TCGAAACCAGGAACTGAGTCAAAGTGTTTCATCAACAACAAGACCATTGCTTCGACAAATAGAAAATTTGCAAGCAACCCTGGGATCCCA
GACATCGTCGTGGGAGAAATTAGAGAAGAATCTTTCTGATAGGCTTGGTGAATCCCAGACCTTGCTGGCAGCAGCAGTTGAGAGAGAACG
TGCAGCTACAGAAGAACTCCTTGCTAACAAAATTCAGATGTCTTCCATGGAGTCACAGAATTCTCTTTTAAGACAGGAAAACAGTAGATT
TCAAGCCCAGCTAGAATCAGAGAAAAATAGGCTGTGTAAACTGGAGGATGAGAACAATAGGTACCAGGTTGAATTGGAAAACCTAAAAGA
TGAATATGTAAGAACACTTGAAGAGACGAGGAAAGAAAAGATGACAGAAGGCAGGCACTGCCAGGTGCACCTCCTGGATGATAGGAGACT
GGAGCTGCTGGTTCAGCCCAAACTTCTAGCAAGAGAGTTGCTGGACCTAGTGGCTTCACATTTCAACCTGAAAGAAAAGGAGTATTTTGG
AATAACATTCATAGATGACACAGGTCAGCAGAACTGGCTGCAGTTAGATCACCGAGTTCTTGACCACGATTTGCCCAAGAAACCAGGCCC
AACCATTTTGCACTTTGCTGTGAGGTTTTACATTGAGAGCATATCGTTTTTAAAGGATAAAACCACCGTGGAGCTGTTTTTCCTGAATGC
AAAGGCCTGTGTGCACAAGGGGCAAATCGAAGTAGAGAGCGAAACCATCTTCAAGTTAGCAGCGTTTATTTTACAGTCTCCCAAAGTCTC
GCTTACCCATGATGAAAATGCCAGGAAAGATTTAAAGACATTACCAGCCTTTCCAACCAAAACTCTTCAGGAGCATCCATCCCTTGCCTA
CTGTGAGGACAGGGTAATTGAGCATTATTTGAAAATCAAAGGTCTCACTCGAGGTCAAGCTGTGGTTCAGTATATGAAAATAGTAGAAGC
TCTACCGACTTACGGTGTCCATTATTATGCAGTAAAGGATAAGCAAGGACTTCCTTGGTGGCTTGGAATAAGCTATAAGGGAATTGGCCA
ATATGATATACAAGACAAGGTGAAGCCTCGGAAGTTATTCCAATGGAAACAGCTGGAGAACTTATATTTCCGTGAGAAAAAATTTGCTGT
TGAAGTTCATGATCCACGAAGGATTTCAGTTTCAAGAAGAACCTTTGGGCAAAGTGGCTTGTTTGTGCAAACATGGTATGCTAACTCTTC
TCTCATCAAGTCCATTTGGGTAATGGCAATTAGTCAGCATCAGTTTTACTTGGACCGGAAGCAAAGCAAAGCAAAAATTCCTTCAGCCAG
GAGTTTAGATGAGATTGCAATGGATTTGACAGAGACAGGAACACAAAGGGCCTCCAAGCTGGTGACACTGGAGACGAAAAGTCAGTTCAT
CATGGCAAGTAATGGCAGTTTAATCTCCTCAGGTTCTCAAGACTCAGAAGTTAGTGAAGAGCAAAAGAGAGAAAAAATCCTTGAACTAAA
GAAGAAGGAGAAACTATTACAAGAAAAACTTCTGAAAAAAGTTGAGGAGCTTAAGAAGATCTGTCTGCGGGAGGCTGAGCTCACAGGCAA
AATGCCAAAGGAGTATCCCCTGAACATAGGCGAGAAGCCTCCTCAGGTCAGAAGACGTGTGGGTACTGCGTTCAAATTAGATGACAACTT
GCTGCCGAGTGAAGAAGATCCTGCTTTGCAAGAACTGGAGAGTAATTTTCTAATACAACAAAAGCTGGTGGAAGCTGCAAAGAAACTTGC
CAATGAGCCAGACCTTTGTAAAACTGTGAAGAAAAAGCGAAAGCAAGATTACACAGATGCGATGAAAAAGCTTCAGGAGATTGAAAATGC
AATAAACGAATACCGAATTAGGTGTGGAAAGAAACCCAGCCAGAAAGCAACAGTGTTACCAGAAGACATAATCCCCTCAGAGAGTAGCTC
TTTGTCTGACACCACCACCTATGATGATCCCAGTGATGCCTTCACTTTTCCTGGGCAGCGATCAAGTTCAGTACCTCATTCTCCAAGAAT
TCTTCCCCCCAAGTCTCTTGGTATTGAGCGAATCCATTTCAGAAAGTCGTCCATCAATGAACAGTTTGTGGATACCAGGCAGTCCAGAGA
AATGCTGTCCACACACAGCAGCCCTTACAAAACTCTGGAGAGGCGGCCCCAGGGAGGACGAAGCATGCCCACCACGCCAGTTCTTACCCG
AAACGCCTACAGCAGCAGCCACTTGGAACCCGAATCTTCATCTCAGCACTGCCGCCAGCGGAGTGGAAGCCTGGAGTCCCAGTCCCACCT
GCTCTCCGAGATGGACAGCGATAAGCCATTTTTCTCCCTCTCCAAATCCCAAAGAAGCAGCAGCACAGAAATCCTCGATGACGGGTCTTC
TTATACAAGCCAATCAAGCACAGAGTATTACTGTGTGACACCAGTTACCGGCCCCTATTACACCACCCAGACCCTGGACACTCGCACCAG
GGGTCGGAGGAGGTCAAAGAAACAGAATGTTTCTACTTCAAATTCAGGAAGCATGCCCAACCTAGCACAAAAGGATAGTTTGAGGAATGG
TGTTTACTCAAAGAGTCAGGAGCCACCGTCTTCCAGTTACTACATTGCCGGGTACACACCCTATGCAGAGTGTGACTTTTATTACAGTGG
TGGTTATGTCTATGAGAATGACACCGAGGGACAGTATAGTGTCAACCCTTCCTACCGGTCCTCAGCCCACTATGGATATGAGCGCCAGAG
GGACTACAGCAGATCCTTTCACGAAGATGAGGTCGACCGGGTACCCCATAACCCATATGCAACTCTCCGGCTGCCAAGGAAGGCTGCTGC
AAAATCGGAGCACATCACCAAAAACATCCACAAGGCCTTAGTTGCCGAGCACTTGCGTGGCTGGTACCAGCGGGCCTCTGGGCAGAAGGA
TCAGGGACACAGCCCGCAGACCAGCTTTGACTCAGACAGGGGATCACAGAGATGCCTGGGGTTTGCGGGGCTGCAAGTACCTTGTTCTCC
AAGCAGTCGTGCATCCTCGTACTCTTCAGTGTCTTCTACAAATGCTTCTGGGAACTGGAGGACCCAGTTAACCATAGGGCTGTCGGATTA
CGAGACTCCAGCACATTCTTCTTACACCAGCTGCTATGGCAATGTCTATAATCCTTTACCCTCTCCAAGCAGACAATACACAGAAATCAG
TCAACTGGATGGTACAGATGGAAACCAGCTGGAAGACAACCTGGAGAGTAGTGAGCAGAGACTCTTTTGGCATGAAGATTCAAAGCCTGG
AACATTAGTCTGAACTGCAGTTGGACCTCCTGACCAAGCACTGCGTTCTCACACTAGTGTGCCTTGCAAATTGTATTTGTCTTCCGAGAG
GATGTTCGTTTTAGAAACCTAAAGACATCAAAGGTTGAAGAGAAGACTTAGTTGCCCTGGAAGTGAATCAGTGAATCACACACCAAGCCC
CACAAAGCCCCTAAAGGAGGATTTGGCCTTTCAAACTCTAGGCACTAACGTAACTGTAGGGTCTGCCCACATGTTGAAGTATTGCCAAGA
GAGGACTCAGTGTGAAGCCTTCATCAATAGCAAGCACTTTTTAAGGGAGTAAAAGTTGTTAAAGGCAAACCTCAAAAACATGAAAGGGCA
TTCAGGATGTCCCATGGCAATAAGAACAGGGGAAATCTCAGAGCACAATTCAGCAGGATGAGAGAAGGGGAACCAGAAGCTCCGGAGTCA
TTGCTCACTTCAGAGTTTGAATTCGTGAGCTGACAAAGAGTAACATGCTCTTTCTACACAGACATGGACAATTTAGACAGTATTGGAAAA
TTACTTGAAGCTGGATTTTCATGAAGTTCTGAATGAGTGTAAATGTTTTTTAGGATACTATAAAGAGTGATGTTTTTCATAAGCACCATA
AAATGGGTTCTGGAAAAACTGATTACCTTAGCATCCTGTAATATAACTTATGGTAGCAGATTGGGGAAAATGAAGCAGCCCACTGAATAA
TTGACAAAGTCTGCTTGGAGAACATTCTAAGGTACAATATCATGGAGCTCCTTTTTCCTTTCTCCACTAATTGCGTGATGAGCTATTGTT
CTGGCTGTTAATTCTCCAACTCGGCTGTCATTTGAAGTGGCAGACTTAATATGGAAAGTTTTTATAATTATGAGTTTGAAAAAGCATTTT
AAGATGATACAGAAAGTATCCAAAACAACAGAAAAAAAAAGCCACGTCATTTTAGATGAATTGCGTGCCTTAAAATGGTGAACGTTAGAA
AATTAAACAAGTCTGGATTCCACAAGTAGTTCCAAGTCACCAAGTGACAAAAACAAGGTTAACATTAAAAAAGAAAAACAACAACAACGA
CAAAAAGCTCCAAGCTGCAGTGGATTTAATTATGAGGCTAAAACTACCTCATACTTTCCTTGGAAGAACTAATTAGCTATGGTTTATTGT
AGGGTTTTGTTTGTTTGTTTTTTAAAGCAAATGATTTCCATATTCCAGATTGATCTTTTTTGTCATCTTTGCTTCAAAATTACATAAAAG
GTGCTCCTTTCCCCCTTCTTTTATACAAGTTTCTTGTTCATATTGTGAATAGAAAAGTTTCTGAACAACTTTTTTGGAACATTTTCTATC
TATATTCCAAAGCATGTAATATATACATAAAAACGATTTGTTAAACTGGTCCTTAGTCATTTGTATAATTAGAAATGAAGTTTGGGAAAA
AATTTTGGAAAAAAGACAAGCAAAAAAAAATAACTTATTCCTTTTTTGCATATTTGTATAGCCTTCTAGAATCAGAAATAACCTTTTTGC
ATATTCTTTTATTGTTCTGACTTTTCAAGACCTATTATTTTTTTACATAGGTCAATAAACAAAAGGTGTGCTACTGAAAATGTTTACGTT
TTCTTCCATTTATGTCAGGGGTTCATGTGAAGCAGGTCGCAGTGCTCTACTTCAAGTAATCATATTGGGCAAGGCTTCGGATTTTTATTT
ATAGTATTACCGTATTTTATTAATTCCGGGATGTACATTTTTAAATATTTACATTAAAAACATGGTTCATCTTTTTATTGATGGCATATT

>92306_92306_8_TMF1-FRMD4B_TMF1_chr3_69077377_ENST00000543976_FRMD4B_chr3_69362668_ENST00000542259_length(amino acids)=1871AA_BP=891
MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTSTWGLKSNTEPQSPPIASPKAITKPVRRTVV
DESENFFSAFLSPTDVQTIQKSPVVSKPPAKSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEET
VNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSNTPSPPVSTFSSGTSTTSDIEVLDHESVISE
SSASSRQETTDSKSSLHLMQTSFQLLSASACPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIV
NSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKV
TLTVEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELAT
RLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKK
LNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQ
VGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSDRLGESQTLL
AAAVERERAATEELLANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKMTEGRHCQV
HLLDDRRLELLVQPKLLARELLDLVASHFNLKEKEYFGITFIDDTGQQNWLQLDHRVLDHDLPKKPGPTILHFAVRFYIESISFLKDKTT
VELFFLNAKACVHKGQIEVESETIFKLAAFILQSPKVSLTHDENARKDLKTLPAFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVV
QYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFV
QTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQFIMASNGSLISSGSQDSEVSEEQK
REKILELKKKEKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQKL
VEAAKKLANEPDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLPEDIIPSESSSLSDTTTYDDPSDAFTFPGQRSS
SVPHSPRILPPKSLGIERIHFRKSSINEQFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPESSSQHCRQRSG
SLESQSHLLSEMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRTRGRRRSKKQNVSTSNSGSMPNLA
QKDSLRNGVYSKSQEPPSSSYYIAGYTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQRDYSRSFHEDEVDRVPHNPYATL
RLPRKAAAKSEHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQ

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Fusion Gene PPI Analysis for TMF1-FRMD4B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneTMF1chr3:69075147chr3:69362668ENST00000398559-1417333_342953.01094.0Elongin BC complex
HgeneTMF1chr3:69075147chr3:69362668ENST00000543976-1417333_342956.01097.0Elongin BC complex
HgeneTMF1chr3:69077377chr3:69362668ENST00000398559-1217333_342888.01094.0Elongin BC complex
HgeneTMF1chr3:69077377chr3:69362668ENST00000543976-1217333_342891.01097.0Elongin BC complex


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TMF1-FRMD4B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TMF1-FRMD4B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource