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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TMTC2-PPFIA2 (FusionGDB2 ID:92517)

Fusion Gene Summary for TMTC2-PPFIA2

check button Fusion gene summary
Fusion gene informationFusion gene name: TMTC2-PPFIA2
Fusion gene ID: 92517
HgeneTgene
Gene symbol

TMTC2

PPFIA2

Gene ID

160335

8499

Gene nametransmembrane O-mannosyltransferase targeting cadherins 2PTPRF interacting protein alpha 2
SynonymsIBDBP1-
Cytomap

12q21.31

12q21.31

Type of geneprotein-codingprotein-coding
Descriptionprotein O-mannosyl-transferase TMTC2transmembrane and TPR repeat-containing protein 2transmembrane and tetratricopeptide repeat containing 2liprin-alpha-2protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
Modification date2020032920200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000321196, ENST00000549919, 
ENST00000548305, 		ENST00000333447, 
ENST00000407050, ENST00000443686, 
ENST00000545296, ENST00000548586, 
ENST00000550359, ENST00000552948, 
ENST00000541017, ENST00000541570, 
ENST00000549325, ENST00000549396, 
ENST00000550584, 
Fusion gene scores* DoF score11 X 7 X 5=38517 X 12 X 4=816
# samples 1116
** MAII scorelog2(11/385*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/816*10)=-2.35049724708413
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TMTC2 [Title/Abstract] AND PPFIA2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTMTC2(83455610)-PPFIA2(81851645), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across TMTC2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PPFIA2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A06Q-01ATMTC2chr12

83455610

-PPFIA2chr12

81851645

-
ChimerDB4BRCATCGA-A8-A06Q-01ATMTC2chr12

83455610

+PPFIA2chr12

81851645

-


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Fusion Gene ORF analysis for TMTC2-PPFIA2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000321196ENST00000333447TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-5UTRENST00000321196ENST00000407050TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-5UTRENST00000321196ENST00000443686TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-5UTRENST00000321196ENST00000545296TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-5UTRENST00000321196ENST00000548586TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-5UTRENST00000321196ENST00000550359TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-5UTRENST00000321196ENST00000552948TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-5UTRENST00000549919ENST00000333447TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-5UTRENST00000549919ENST00000407050TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-5UTRENST00000549919ENST00000443686TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-5UTRENST00000549919ENST00000545296TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-5UTRENST00000549919ENST00000548586TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-5UTRENST00000549919ENST00000550359TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-5UTRENST00000549919ENST00000552948TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-intronENST00000321196ENST00000541017TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-intronENST00000321196ENST00000541570TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-intronENST00000549919ENST00000541017TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
5CDS-intronENST00000549919ENST00000541570TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
In-frameENST00000321196ENST00000549325TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
In-frameENST00000321196ENST00000549396TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
In-frameENST00000321196ENST00000550584TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
In-frameENST00000549919ENST00000549325TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
In-frameENST00000549919ENST00000549396TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
In-frameENST00000549919ENST00000550584TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
intron-3CDSENST00000548305ENST00000549325TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
intron-3CDSENST00000548305ENST00000549396TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
intron-3CDSENST00000548305ENST00000550584TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
intron-5UTRENST00000548305ENST00000333447TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
intron-5UTRENST00000548305ENST00000407050TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
intron-5UTRENST00000548305ENST00000443686TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
intron-5UTRENST00000548305ENST00000545296TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
intron-5UTRENST00000548305ENST00000548586TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
intron-5UTRENST00000548305ENST00000550359TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
intron-5UTRENST00000548305ENST00000552948TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
intron-intronENST00000548305ENST00000541017TMTC2chr12

83455610

+PPFIA2chr12

81851645

-
intron-intronENST00000548305ENST00000541570TMTC2chr12

83455610

+PPFIA2chr12

81851645

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000321196TMTC2chr1283455610+ENST00000549396PPFIA2chr1281851645-7937303865065081952
ENST00000321196TMTC2chr1283455610+ENST00000550584PPFIA2chr1281851645-7844303865064781942
ENST00000321196TMTC2chr1283455610+ENST00000549325PPFIA2chr1281851645-7243303865064871945
ENST00000549919TMTC2chr1283455610+ENST00000549396PPFIA2chr1281851645-90174118167075881972
ENST00000549919TMTC2chr1283455610+ENST00000550584PPFIA2chr1281851645-89244118167075581962
ENST00000549919TMTC2chr1283455610+ENST00000549325PPFIA2chr1281851645-83234118167075671965

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000321196ENST00000549396TMTC2chr1283455610+PPFIA2chr1281851645-0.0011958590.9988041
ENST00000321196ENST00000550584TMTC2chr1283455610+PPFIA2chr1281851645-0.0012589690.9987411
ENST00000321196ENST00000549325TMTC2chr1283455610+PPFIA2chr1281851645-0.0018782150.9981218
ENST00000549919ENST00000549396TMTC2chr1283455610+PPFIA2chr1281851645-0.0018956930.99810433
ENST00000549919ENST00000550584TMTC2chr1283455610+PPFIA2chr1281851645-0.0019462520.9980538
ENST00000549919ENST00000549325TMTC2chr1283455610+PPFIA2chr1281851645-0.0024548030.9975452

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Fusion Genomic Features for TMTC2-PPFIA2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TMTC2-PPFIA2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:83455610/chr12:81851645)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112462_492777837.0RepeatNote=TPR 1
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112493_526777837.0RepeatNote=TPR 2
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112527_560777837.0RepeatNote=TPR 3
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112562_594777837.0RepeatNote=TPR 4
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112606_639777837.0RepeatNote=TPR 5
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112643_676777837.0RepeatNote=TPR 6
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112677_710777837.0RepeatNote=TPR 7
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112712_744777837.0RepeatNote=TPR 8
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112746_778777837.0RepeatNote=TPR 9
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112108_128777837.0TransmembraneHelical
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112133_153777837.0TransmembraneHelical
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112163_183777837.0TransmembraneHelical
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112184_204777837.0TransmembraneHelical
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112222_241777837.0TransmembraneHelical
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112313_333777837.0TransmembraneHelical
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112400_420777837.0TransmembraneHelical
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112423_443777837.0TransmembraneHelical
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112450_470777837.0TransmembraneHelical
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+111285_105777837.0TransmembraneHelical
TgenePPFIA2chr12:83455610chr12:81851645ENST000004070500291081_1107271033.6666666666667Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000407050029185_541271033.6666666666667Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST0000040705002929_154271033.6666666666667Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000407050029643_695271033.6666666666667Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST000004436860281081_1107271153.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000443686028185_541271153.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST0000044368602829_154271153.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000443686028643_695271153.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST000005410170221081_11070557.6666666666666Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000541017022185_5410557.6666666666666Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST0000054101702229_1540557.6666666666666Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000541017022643_6950557.6666666666666Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST000005415700201081_11070784.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000541570020185_5410784.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST0000054157002029_1540784.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000541570020643_6950784.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST000005485862311081_11071011252.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000548586231185_5411011252.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000548586231643_6951011252.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST000005493251311081_1107831233.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000549325131185_541831233.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000549325131643_695831233.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST000005493963331081_11071011700.6666666666667Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000549396333185_5411011700.6666666666667Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000549396333643_6951011700.6666666666667Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST000005529482301081_11071011237.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000552948230185_5411011237.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000552948230643_6951011237.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST00000407050029115_528271033.6666666666667Compositional biasNote=Glu-rich
TgenePPFIA2chr12:83455610chr12:81851645ENST00000407050029622_627271033.6666666666667Compositional biasNote=Poly-Asp
TgenePPFIA2chr12:83455610chr12:81851645ENST00000443686028115_528271153.0Compositional biasNote=Glu-rich
TgenePPFIA2chr12:83455610chr12:81851645ENST00000443686028622_627271153.0Compositional biasNote=Poly-Asp
TgenePPFIA2chr12:83455610chr12:81851645ENST00000541017022115_5280557.6666666666666Compositional biasNote=Glu-rich
TgenePPFIA2chr12:83455610chr12:81851645ENST00000541017022622_6270557.6666666666666Compositional biasNote=Poly-Asp
TgenePPFIA2chr12:83455610chr12:81851645ENST00000541570020115_5280784.0Compositional biasNote=Glu-rich
TgenePPFIA2chr12:83455610chr12:81851645ENST00000541570020622_6270784.0Compositional biasNote=Poly-Asp
TgenePPFIA2chr12:83455610chr12:81851645ENST00000548586231115_5281011252.0Compositional biasNote=Glu-rich
TgenePPFIA2chr12:83455610chr12:81851645ENST00000548586231622_6271011252.0Compositional biasNote=Poly-Asp
TgenePPFIA2chr12:83455610chr12:81851645ENST00000549325131115_528831233.0Compositional biasNote=Glu-rich
TgenePPFIA2chr12:83455610chr12:81851645ENST00000549325131622_627831233.0Compositional biasNote=Poly-Asp
TgenePPFIA2chr12:83455610chr12:81851645ENST00000549396333115_5281011700.6666666666667Compositional biasNote=Glu-rich
TgenePPFIA2chr12:83455610chr12:81851645ENST00000549396333622_6271011700.6666666666667Compositional biasNote=Poly-Asp
TgenePPFIA2chr12:83455610chr12:81851645ENST00000552948230115_5281011237.0Compositional biasNote=Glu-rich
TgenePPFIA2chr12:83455610chr12:81851645ENST00000552948230622_6271011237.0Compositional biasNote=Poly-Asp
TgenePPFIA2chr12:83455610chr12:81851645ENST000004070500291020_1084271033.6666666666667DomainSAM 2
TgenePPFIA2chr12:83455610chr12:81851645ENST000004070500291108_1177271033.6666666666667DomainSAM 3
TgenePPFIA2chr12:83455610chr12:81851645ENST00000407050029898_964271033.6666666666667DomainSAM 1
TgenePPFIA2chr12:83455610chr12:81851645ENST000004436860281020_1084271153.0DomainSAM 2
TgenePPFIA2chr12:83455610chr12:81851645ENST000004436860281108_1177271153.0DomainSAM 3
TgenePPFIA2chr12:83455610chr12:81851645ENST00000443686028898_964271153.0DomainSAM 1
TgenePPFIA2chr12:83455610chr12:81851645ENST000005410170221020_10840557.6666666666666DomainSAM 2
TgenePPFIA2chr12:83455610chr12:81851645ENST000005410170221108_11770557.6666666666666DomainSAM 3
TgenePPFIA2chr12:83455610chr12:81851645ENST00000541017022898_9640557.6666666666666DomainSAM 1
TgenePPFIA2chr12:83455610chr12:81851645ENST000005415700201020_10840784.0DomainSAM 2
TgenePPFIA2chr12:83455610chr12:81851645ENST000005415700201108_11770784.0DomainSAM 3
TgenePPFIA2chr12:83455610chr12:81851645ENST00000541570020898_9640784.0DomainSAM 1
TgenePPFIA2chr12:83455610chr12:81851645ENST000005485862311020_10841011252.0DomainSAM 2
TgenePPFIA2chr12:83455610chr12:81851645ENST000005485862311108_11771011252.0DomainSAM 3
TgenePPFIA2chr12:83455610chr12:81851645ENST00000548586231898_9641011252.0DomainSAM 1
TgenePPFIA2chr12:83455610chr12:81851645ENST000005493251311020_1084831233.0DomainSAM 2
TgenePPFIA2chr12:83455610chr12:81851645ENST000005493251311108_1177831233.0DomainSAM 3
TgenePPFIA2chr12:83455610chr12:81851645ENST00000549325131898_964831233.0DomainSAM 1
TgenePPFIA2chr12:83455610chr12:81851645ENST000005493963331020_10841011700.6666666666667DomainSAM 2
TgenePPFIA2chr12:83455610chr12:81851645ENST000005493963331108_11771011700.6666666666667DomainSAM 3
TgenePPFIA2chr12:83455610chr12:81851645ENST00000549396333898_9641011700.6666666666667DomainSAM 1
TgenePPFIA2chr12:83455610chr12:81851645ENST000005529482301020_10841011237.0DomainSAM 2
TgenePPFIA2chr12:83455610chr12:81851645ENST000005529482301108_11771011237.0DomainSAM 3
TgenePPFIA2chr12:83455610chr12:81851645ENST00000552948230898_9641011237.0DomainSAM 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTMTC2chr12:83455610chr12:81851645ENST00000321196+1112779_812777837.0RepeatNote=TPR 10
TgenePPFIA2chr12:83455610chr12:81851645ENST0000054858623129_1541011252.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST0000054932513129_154831233.0Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST0000054939633329_1541011700.6666666666667Coiled coilOntology_term=ECO:0000255
TgenePPFIA2chr12:83455610chr12:81851645ENST0000055294823029_1541011237.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for TMTC2-PPFIA2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>92517_92517_1_TMTC2-PPFIA2_TMTC2_chr12_83455610_ENST00000321196_PPFIA2_chr12_81851645_ENST00000549325_length(transcript)=7243nt_BP=3038nt
GTCACGCAGGCGCGGGGGGCCGCGTCGAGAACCCCACGCGGGAGCTTCTGGAGTCTCCAGCCACCGCTTCTCACTTCACTGGAGAAGGGA
GCTGGGGCTGGGGCTGGGGCTGGGGCTGGGAGGGAGCTAATAAACATTGAATGTGCAGCAGCTGCCTTGGCGGCCGGAGTCCGCCCGAGC
GACACCGGAGCAGTGCGCCCGGGAGGCGGCGAGGGGAGGCGGTTCGCCTTGTCCCTCCCACCCGCGCCTCTTTCTCTCTCTTCCTCCAGC
TGGTCCCAGAGCCCGGCTTGGTCCGGTCCCTCTGCCCCCATCCCGCACCCTTCCACCTCCTCCGAGTCCCACTCCTCACCTAGGACGCCC
CAAACTGCCATGGGTTAGGGTGGGGATCGCGACCCGCGCGAAAGACCAGCCCTGCGCTTCCGCCGGGGGACGCGGAGCCCAAACGCCGCT
CACCGCTTGCGGGCGCCGGGCATGGGGAGTGTGGTGTGAGCCCGCACCCGGGGAGGACGCAGGAGCTGCGGAGACGGGCGCGAGGAGGAG
GAGAGGAGTCGTGGATTGGAAGGACCCGAGGGAGGGAGGGTGGGGAAGCGAGGGAAAAGTGAAGCTGGGAGGAGAAGGCGGCGGAAGGTG
GAGATTGATGCTTCTGTTTTTTGTTGCCGCTGCTGCCCTCGCGCTGGGAGCCGAGCCGGAGGGAAGGCGGTGGAGAGATGATTGCAGAGT
TGGTGAGCAGCGCTCTGGGGCTCGCCTTGTATCTCAACACCCTGAGTGCGGATTTCTGCTATGATGACAGCCGTGCTATCAAGACTAATC
AGGACCTTCTCCCAGAAACTCCATGGACGCACATTTTCTACAATGATTTTTGGGGGACTCTTCTAACCCACAGTGGCAGCCACAAGTCCT
ACCGGCCACTCTGCACTCTTTCTTTTCGCCTGAACCATGCCATTGGAGGGTTGAATCCCTGGAGCTACCATCTTGTCAATGTCCTGTTGC
ATGCAGCAGTCACTGGTCTCTTCACAAGCTTCTCCAAGATCCTCCTTGGTGATGGATACTGGACATTCATGGCTGGCTTGATGTTTGCTT
CTCACCCCATTCACACGGAGGCAGTGGCAGGAATCGTGGGACGAGCCGATGTCGGGGCCAGTCTCTTCTTTCTCCTCTCCTTGCTCTGCT
ACATTAAACACTGTTCTACAAGAGGCTACTCAGCCAGAACCTGGGGCTGGTTCCTGGGGTCAGGACTGTGCGCAGGATGCAGCATGTTGT
GGAAGGAACAAGGAGTGACTGTTCTCGCAGTTTCAGCAGTTTATGATGTCTTTGTCTTTCACAGGCTGAAAATAAAACAGATATTACCTA
CCATTTACAAAAGGAAGAACTTGTCGCTTTTCCTAAGCATTAGTTTGTTAATTTTCTGGGGTTCCTCCCTTTTGGGTGCCCGGTTATACT
GGATGGGAAACAAACCACCAAGCTTTTCCAACTCGGACAACCCCGCTGCTGATTCGGACAGCCTCCTCACCCGCACTCTCACCTTCTTCT
ACTTGCCAACCAAGAACCTCTGGCTGTTGCTATGTCCAGATACCCTCAGTTTTGATTGGTCAATGGATGCTGTGCCTCTGCTCAAAACAG
TTTGTGACTGGAGAAACCTACACACTGTGGCCTTCTATACTGGACTCCTTCTCCTTGCCTACTATGGTTTGAAGAGCCCGAGCGTAGACA
GAGAATGCAATGGGAAAACTGTAACAAATGGCAAGCAGAATGCAAATGGACATAGCTGCCTTTCAGATGTGGAGTACCAGAACTCAGAGA
CTAAGTCCAGCTTTGCATCCAAAGTAGAAAATGGCATTAAAAACGATGTATCACAGAGAACCCAGCTTCCTTCTACGGAGAACATTGTTG
TTCTGTCTTTATCTTTGTTAATCATACCCTTTGTTCCTGCCACGAACCTGTTTTTCTATGTCGGCTTTGTAATTGCAGAGCGAGTATTAT
ATATTCCTAGTATGGGCTTCTGCCTACTGATTACAGTGGGTGCTAGAGCCCTTTATGTCAAAGTCCAAAAGCGGTTCCTCAAGAGCTTGA
TTTTTTATGCTACAGCTACACTAATTGTTTTTTATGGACTCAAGACTGCGATCAGGAATGGAGACTGGCAGAATGAGGAAATGCTTTATA
GATCAGGGATAAAAGTAAACCCAGCTAAAGCATGGGGTAACCTTGGAAATGTTCTGAAGAGTCAGAGCAAAATTTCTGAAGCTGAAAGCG
CCTATAGAAATGCTTTGTACTACCGCAGCAACATGGCTGACATGCTTTATAATTTAGGGCTACTTCTCCAGGAGAACAGCAGGTTTGCAG
AAGCACTACATTATTATAAATTGGCCATTGGGAGCAGGCCTACCCTGGCTTCTGCATATTTAAATACCGGTATTATTCTAATGAACCAAG
GAAGGACGGAAGAAGCCCGACGGACATTCTTAAAGTGTTCGGAGATCCCAGATGAAAACCTAAAGGACCCTCATGCACACAAGAGCTCTG
TTACCAGTTGTTTGTACAACCTAGGAAAGCTGTATCATGAGCAGGGACACTATGAGGAAGCCCTTAGTGTATACAAGGAAGCAATTCAGA
AAATGCCAAGGCAGTTTGCCCCACAGAGCTTGTACAACATGATGGGTGAAGCATATATGCGTTTAAGCAAACTCCCCGAAGCAGAGCATT
GGTATATGGAATCACTGAGATCCAAGACTGACCACATCCCTGCTCATCTCACCTATGGGAAGCTGCTAGCTCTAACAGGTCGTAAGAGTG
AGGCTGAAAAGCTCTTCTTGAAGGCTATTGAGCTGGATCCCACCAAAGGAAACTGTTACATGCATTATGGTCAGTTTCTTCTGGAAGAAG
CTCGTCTCATAGAAGCAGCTGAGATGGCAAAAAAAGCAGCTGAACTAGACAGCACAGAGTTTGATGTTGTCTTCAATGCTGCCCACATGC
TCAGACAGGCTAGCCTCAATGAAGCAGCTGAGAAGTATTATGATCTGGCAGCCAGGCTGAGGCCTAATGAATTTGCTGCACTGACAAAAG
AATTAAATGCCTGCAGGGAACAACTTCTAGAAAAGGAAGAAGAAATCTCTGAACTTAAAGCTGAAAGAAACAACACAAGACTATTACTGG
AGCATTTGGAGTGCCTTGTGTCACGACATGAAAGATCACTAAGAATGACGGTGGTAAAACGGCAAGCCCAGTCTCCCTCAGGAGTATCCA
GTGAAGTTGAAGTTCTCAAGGCACTGAAATCTTTGTTTGAGCACCACAAGGCCTTGGATGAAAAGGTAAGGGAGCGACTGAGGGTTTCTT
TAGAAAGAGTCTCTGCACTGGAAGAAGAACTAGCTGCTGCTAATCAGGAGATTGTTGCCTTGCGTGAACAAAATGTTCATATACAAAGAA
AAATGGCATCAAGCGAGGGATCCACAGAGTCAGAACATCTTGAAGGGATGGAACCTGGACAGAAAGTCCATGAGAAGCGTTTGTCCAATG
GTTCTATAGACTCAACCGATGAAACTAGTCAAATAGTTGAACTACAAGAATTGCTTGAAAAGCAAAACTATGAAATGGCCCAGATGAAAG
AACGTTTAGCAGCCCTTTCTTCCCGAGTGGGAGAGGTGGAACAGGAAGCAGAGACAGCAAGAAAGGATCTCATTAAAACAGAAGAAATGA
ACACCAAGTATCAAAGGGACATTAGGGAGGCCATGGCACAAAAGGAAGATATGGAAGAAAGAATTACAACCCTTGAAAAGCGTTACCTCA
GTGCTCAGAGAGAATCTACCTCCATACATGACATGAATGATAAACTAGAAAATGAGTTAGCAAATAAAGAAGCTATCCTGCGGCAGATGG
AAGAGAAAAACAGACAGTTACAAGAACGTCTTGAGCTAGCTGAACAAAAGTTGCAGCAGACCATGAGAAAGGCTGAAACCTTGCCTGAAG
TAGAGGCTGAACTGGCTCAGAGAATTGCAGCCCTAACCAAGGCTGAAGAGAGACATGGAAATATTGAAGAACGTATGAGACATTTAGAGG
GTCAACTTGAAGAGAAGAATCAAGAACTTCAAAGAGCTAGGCAAAGAGAGAAAATGAATGAGGAGCATAACAAGAGATTATCGGATACGG
TTGATAGACTTCTGACTGAATCCAATGAACGCCTACAACTACACTTAAAGGAAAGAATGGCTGCTCTAGAAGAAAAGAATGTTTTAATTC
AAGAATCAGAAACTTTCAGAAAGAATCTTGAAGAATCTTTACATGATAAGGAAAGATTAGCAGAAGAAATTGAAAAGCTGAGATCTGAAC
TTGACCAATTGAAAATGAGAACTGGCTCTTTAATTGAACCCACAATACCAAGAACTCATCTAGACACCTCAGCTGAGTTGCGGTACTCAG
TGGGATCCCTAGTGGACAGCCAGTCTGATTACAGAACAACTAAAGTAATAAGAAGACCAAGGAGAGGCCGCATGGGTGTGCGAAGAGATG
AGCCAAAGGTGAAATCTCTTGGGGATCACGAGTGGAATAGAACTCAACAGATTGGAGTACTAAGCAGCCACCCTTTTGAAAGTGACACTG
AAATGTCTGATATTGATGATGATGACAGAGAAACAATTTTTAGCTCAATGGATCTTCTCTCTCCAAGTGGTCATTCCGATGCCCAGACGC
TAGCCATGATGCTTCAGGAACAATTGGATGCCATCAACAAAGAAATCAGGCTAATTCAGGAAGAAAAAGAATCTACAGAGTTGCGTGCTG
AAGAAATTGAAAATAGAGTGGCTAGTGTGAGCCTCGAAGGCCTGAATTTGGCAAGGGTCCACCCAGGTACCTCCATTACTGCCTCTGTTA
CAGCTTCATCGCTGGCCAGTTCATCTCCCCCCAGTGGACACTCAACTCCAAAGCTCACCCCTCGAAGCCCTGCCAGGGAAATGGATCGGA
TGGGAGTCATGACACTGCCAAGTGATCTGAGGAAACATCGGAGAAAGATTGCAGTTGTGGAAGAAGATGGTCGAGAGGACAAAGCAACAA
TTAAATGTGAAACTTCTCCTCCTCCTACCCCTAGAGCCCTCAGAATGACTCACACTCTCCCTTCTTCCTACCACAATGATGCTCGAAGTA
GTTTATCTGTCTCTCTTGAGCCAGAAAGCCTCGGGCTTGGTAGTGCCAACAGCAGCCAAGACTCTCTTCACAAAGCCCCCAAGAAGAAAG
GAATCAAGTCTTCAATAGGACGTTTGTTTGGTAAAAAAGAAAAAGCTCGACTTGGGCAGCTCCGAGGCTTTATGGAGACTGAAGCTGCAG
CTCAGGAGTCCCTGGGGTTAGGCAAACTCGGAACTCAAGCTGAGAAGGATCGAAGACTAAAGAAAAACACATCTGGGCATGAACTTCTTG
AAGAAGCTCGGAGAAAGGGATTACCTTTTGCCCAGTGGGATGGGCCAACTGTGGTCGCATGGCTAGAGCTTTGGTTGGGAATGCCTGCGT
GGTACGTGGCAGCCTGCCGAGCCAACGTGAAGAGTGGTGCCATCATGTCTGCTTTATCTGACACTGAGATCCAGAGAGAAATTGGAATCA
GCAATCCACTGCATCGCTTAAAACTTCGATTAGCAATCCAGGAGATGGTTTCCCTAACAAGTCCTTCAGCTCCTCCAACATCTCGAACTC
CTTCAGGCAACGTTTGGGTGACTCATGAAGAAATGGAAAATCTTGCAGCTCCAGCAAAAACGAAAGAATCTGAGGAAGGAAGCTGGGCCC
AGTGTCCGGTTTTTCTACAGACCCTGGCTTATGGAGATATGAATCATGAGTGGATTGGAAATGAATGGCTTCCCAGCTTGGGGTTACCTC
AGTACAGAAGTTACTTTATGGAATGCTTGGTAGATGCAAGAATGTTAGATCACCTAACAAAAAAAGATCTCCGTGTCCATTTAAAAATGG
TGGATAGTTTCCATCGAACAAGTTTACAATATGGAATTATGTGCTTAAAGAGGTTGAATTATGACAGAAAAGAACTAGAAAGAAGACGGG
AAGCAAGCCAACATGAAATAAAAGACGTGTTGGTGTGGAGCAATGACCGAGTTATTCGCTGGATACAAGCAATTGGACTTCGAGAATATG
CAAATAATATACTTGAGAGCGGTGTGCATGGCTCACTTATAGCCCTGGATGAAAACTTTGACTACAGCAGCTTAGCTTTATTATTACAGA
TTCCAACACAGAACACCCAGGCAAGGCAGATTCTTGAAAGAGAATACAATAACCTCTTGGCCCTGGGAACTGAAAGGCGACTGGATGAAA
GTGATGACAAGAACTTCAGACGTGGATCAACCTGGAGAAGGCAGTTTCCTCCTCGTGAAGTACATGGAATCAGCATGATGCCTGGGTCCT
CAGAAACATTACCAGCTGGATTTAGGTTAACCACAACCTCTGGGCAGTCAAGAAAAATGACAACAGATGATGGCGTCTTTTCAGTCTACT
CTACCTAAAGTGCACTACCATCTAAGAAGACGAGCAGTGAAAACCTTTGTGAAAACTGAATTCTAAGGAAATAATGACGTCATGACTTAT
TAAAAGCTGAAAAATGTGATTTTTGGGGGGAGTCAGATATTACATTTGATTAGTTTACTACAAATTGTAATAAAATGCTTAAGTCATTTG
AATAATAAACATCATCTACATCATAAACTCTGTACAACAGATGCTTTTATGAAATGAAGCCAGTTGTTTTTCATGTTTTATTGTAATATA
CTAGGCATTTATGTATTACCGTGCATTTCTTTTTAAATGTGTAAGTCTTATGTAAATGGATATAAATATGATTTTTTAAAAAATAAAATA
TATGGTTCATGGAGTCTCGAGTGCAAACATTTGACAATTCCAAGTACTGTTTGTATTTTACCATTCCACCATTTTTACAGTTTTTGGATT
GTTAATAGTCAAATCAATATGTTTCCTTGAAGCATGTTTCATGCTTCAACGTGTTTCTCCTTCAAGTCTGTCAATACTTAAAGCTGAACA
ACCTGCCTCTGATCATGTAAAAAAGAATGATTTAACCTGGAACCGGAGCCAAAAATAGAGCTTTAAAGGCAATCAGGGATGTCCTATATC
TTTAGAAATAGCACTGTGATGGCTTGATCTCCTTTTCAATACAAAACAAAGCCAAGCTGTTTACAAGGGTCAAAAGCAATTATTTAAAAA

>92517_92517_1_TMTC2-PPFIA2_TMTC2_chr12_83455610_ENST00000321196_PPFIA2_chr12_81851645_ENST00000549325_length(amino acids)=1945AA_BP=796
MLPLLPSRWEPSRREGGGEMIAELVSSALGLALYLNTLSADFCYDDSRAIKTNQDLLPETPWTHIFYNDFWGTLLTHSGSHKSYRPLCTL
SFRLNHAIGGLNPWSYHLVNVLLHAAVTGLFTSFSKILLGDGYWTFMAGLMFASHPIHTEAVAGIVGRADVGASLFFLLSLLCYIKHCST
RGYSARTWGWFLGSGLCAGCSMLWKEQGVTVLAVSAVYDVFVFHRLKIKQILPTIYKRKNLSLFLSISLLIFWGSSLLGARLYWMGNKPP
SFSNSDNPAADSDSLLTRTLTFFYLPTKNLWLLLCPDTLSFDWSMDAVPLLKTVCDWRNLHTVAFYTGLLLLAYYGLKSPSVDRECNGKT
VTNGKQNANGHSCLSDVEYQNSETKSSFASKVENGIKNDVSQRTQLPSTENIVVLSLSLLIIPFVPATNLFFYVGFVIAERVLYIPSMGF
CLLITVGARALYVKVQKRFLKSLIFYATATLIVFYGLKTAIRNGDWQNEEMLYRSGIKVNPAKAWGNLGNVLKSQSKISEAESAYRNALY
YRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIPDENLKDPHAHKSSVTSCLYN
LGKLYHEQGHYEEALSVYKEAIQKMPRQFAPQSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKLFL
KAIELDPTKGNCYMHYGQFLLEEARLIEAAEMAKKAAELDSTEFDVVFNAAHMLRQASLNEAAEKYYDLAARLRPNEFAALTKELNACRE
QLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSAL
EEELAAANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALS
SRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQL
QERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTE
SNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIPRTHLDTSAELRYSVGSLVDS
QSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQE
QLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLP
SDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRALRMTHTLPSSYHNDARSSLSVSLEPESLGLGSANSSQDSLHKAPKKKGIKSSIG
RLFGKKEKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKNTSGHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACR
ANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTKESEEGSWAQCPVFLQ
TLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEI
KDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDESDDKNFR

--------------------------------------------------------------
>92517_92517_2_TMTC2-PPFIA2_TMTC2_chr12_83455610_ENST00000321196_PPFIA2_chr12_81851645_ENST00000549396_length(transcript)=7937nt_BP=3038nt
GTCACGCAGGCGCGGGGGGCCGCGTCGAGAACCCCACGCGGGAGCTTCTGGAGTCTCCAGCCACCGCTTCTCACTTCACTGGAGAAGGGA
GCTGGGGCTGGGGCTGGGGCTGGGGCTGGGAGGGAGCTAATAAACATTGAATGTGCAGCAGCTGCCTTGGCGGCCGGAGTCCGCCCGAGC
GACACCGGAGCAGTGCGCCCGGGAGGCGGCGAGGGGAGGCGGTTCGCCTTGTCCCTCCCACCCGCGCCTCTTTCTCTCTCTTCCTCCAGC
TGGTCCCAGAGCCCGGCTTGGTCCGGTCCCTCTGCCCCCATCCCGCACCCTTCCACCTCCTCCGAGTCCCACTCCTCACCTAGGACGCCC
CAAACTGCCATGGGTTAGGGTGGGGATCGCGACCCGCGCGAAAGACCAGCCCTGCGCTTCCGCCGGGGGACGCGGAGCCCAAACGCCGCT
CACCGCTTGCGGGCGCCGGGCATGGGGAGTGTGGTGTGAGCCCGCACCCGGGGAGGACGCAGGAGCTGCGGAGACGGGCGCGAGGAGGAG
GAGAGGAGTCGTGGATTGGAAGGACCCGAGGGAGGGAGGGTGGGGAAGCGAGGGAAAAGTGAAGCTGGGAGGAGAAGGCGGCGGAAGGTG
GAGATTGATGCTTCTGTTTTTTGTTGCCGCTGCTGCCCTCGCGCTGGGAGCCGAGCCGGAGGGAAGGCGGTGGAGAGATGATTGCAGAGT
TGGTGAGCAGCGCTCTGGGGCTCGCCTTGTATCTCAACACCCTGAGTGCGGATTTCTGCTATGATGACAGCCGTGCTATCAAGACTAATC
AGGACCTTCTCCCAGAAACTCCATGGACGCACATTTTCTACAATGATTTTTGGGGGACTCTTCTAACCCACAGTGGCAGCCACAAGTCCT
ACCGGCCACTCTGCACTCTTTCTTTTCGCCTGAACCATGCCATTGGAGGGTTGAATCCCTGGAGCTACCATCTTGTCAATGTCCTGTTGC
ATGCAGCAGTCACTGGTCTCTTCACAAGCTTCTCCAAGATCCTCCTTGGTGATGGATACTGGACATTCATGGCTGGCTTGATGTTTGCTT
CTCACCCCATTCACACGGAGGCAGTGGCAGGAATCGTGGGACGAGCCGATGTCGGGGCCAGTCTCTTCTTTCTCCTCTCCTTGCTCTGCT
ACATTAAACACTGTTCTACAAGAGGCTACTCAGCCAGAACCTGGGGCTGGTTCCTGGGGTCAGGACTGTGCGCAGGATGCAGCATGTTGT
GGAAGGAACAAGGAGTGACTGTTCTCGCAGTTTCAGCAGTTTATGATGTCTTTGTCTTTCACAGGCTGAAAATAAAACAGATATTACCTA
CCATTTACAAAAGGAAGAACTTGTCGCTTTTCCTAAGCATTAGTTTGTTAATTTTCTGGGGTTCCTCCCTTTTGGGTGCCCGGTTATACT
GGATGGGAAACAAACCACCAAGCTTTTCCAACTCGGACAACCCCGCTGCTGATTCGGACAGCCTCCTCACCCGCACTCTCACCTTCTTCT
ACTTGCCAACCAAGAACCTCTGGCTGTTGCTATGTCCAGATACCCTCAGTTTTGATTGGTCAATGGATGCTGTGCCTCTGCTCAAAACAG
TTTGTGACTGGAGAAACCTACACACTGTGGCCTTCTATACTGGACTCCTTCTCCTTGCCTACTATGGTTTGAAGAGCCCGAGCGTAGACA
GAGAATGCAATGGGAAAACTGTAACAAATGGCAAGCAGAATGCAAATGGACATAGCTGCCTTTCAGATGTGGAGTACCAGAACTCAGAGA
CTAAGTCCAGCTTTGCATCCAAAGTAGAAAATGGCATTAAAAACGATGTATCACAGAGAACCCAGCTTCCTTCTACGGAGAACATTGTTG
TTCTGTCTTTATCTTTGTTAATCATACCCTTTGTTCCTGCCACGAACCTGTTTTTCTATGTCGGCTTTGTAATTGCAGAGCGAGTATTAT
ATATTCCTAGTATGGGCTTCTGCCTACTGATTACAGTGGGTGCTAGAGCCCTTTATGTCAAAGTCCAAAAGCGGTTCCTCAAGAGCTTGA
TTTTTTATGCTACAGCTACACTAATTGTTTTTTATGGACTCAAGACTGCGATCAGGAATGGAGACTGGCAGAATGAGGAAATGCTTTATA
GATCAGGGATAAAAGTAAACCCAGCTAAAGCATGGGGTAACCTTGGAAATGTTCTGAAGAGTCAGAGCAAAATTTCTGAAGCTGAAAGCG
CCTATAGAAATGCTTTGTACTACCGCAGCAACATGGCTGACATGCTTTATAATTTAGGGCTACTTCTCCAGGAGAACAGCAGGTTTGCAG
AAGCACTACATTATTATAAATTGGCCATTGGGAGCAGGCCTACCCTGGCTTCTGCATATTTAAATACCGGTATTATTCTAATGAACCAAG
GAAGGACGGAAGAAGCCCGACGGACATTCTTAAAGTGTTCGGAGATCCCAGATGAAAACCTAAAGGACCCTCATGCACACAAGAGCTCTG
TTACCAGTTGTTTGTACAACCTAGGAAAGCTGTATCATGAGCAGGGACACTATGAGGAAGCCCTTAGTGTATACAAGGAAGCAATTCAGA
AAATGCCAAGGCAGTTTGCCCCACAGAGCTTGTACAACATGATGGGTGAAGCATATATGCGTTTAAGCAAACTCCCCGAAGCAGAGCATT
GGTATATGGAATCACTGAGATCCAAGACTGACCACATCCCTGCTCATCTCACCTATGGGAAGCTGCTAGCTCTAACAGGTCGTAAGAGTG
AGGCTGAAAAGCTCTTCTTGAAGGCTATTGAGCTGGATCCCACCAAAGGAAACTGTTACATGCATTATGGTCAGTTTCTTCTGGAAGAAG
CTCGTCTCATAGAAGCAGCTGAGATGGCAAAAAAAGCAGCTGAACTAGACAGCACAGAGTTTGATGTTGTCTTCAATGCTGCCCACATGC
TCAGACAGGCTAGCCTCAATGAAGCAGCTGAGAAGTATTATGATCTGGCAGCCAGGCTGAGGCCTAATGAATTTGCTGCACTGACAAAAG
AATTAAATGCCTGCAGGGAACAACTTCTAGAAAAGGAAGAAGAAATCTCTGAACTTAAAGCTGAAAGAAACAACACAAGACTATTACTGG
AGCATTTGGAGTGCCTTGTGTCACGACATGAAAGATCACTAAGAATGACGGTGGTAAAACGGCAAGCCCAGTCTCCCTCAGGAGTATCCA
GTGAAGTTGAAGTTCTCAAGGCACTGAAATCTTTGTTTGAGCACCACAAGGCCTTGGATGAAAAGGTAAGGGAGCGACTGAGGGTTTCTT
TAGAAAGAGTCTCTGCACTGGAAGAAGAACTAGCTGCTGCTAATCAGGAGATTGTTGCCTTGCGTGAACAAAATGTTCATATACAAAGAA
AAATGGCATCAAGCGAGGGATCCACAGAGTCAGAACATCTTGAAGGGATGGAACCTGGACAGAAAGTCCATGAGAAGCGTTTGTCCAATG
GTTCTATAGACTCAACCGATGAAACTAGTCAAATAGTTGAACTACAAGAATTGCTTGAAAAGCAAAACTATGAAATGGCCCAGATGAAAG
AACGTTTAGCAGCCCTTTCTTCCCGAGTGGGAGAGGTGGAACAGGAAGCAGAGACAGCAAGAAAGGATCTCATTAAAACAGAAGAAATGA
ACACCAAGTATCAAAGGGACATTAGGGAGGCCATGGCACAAAAGGAAGATATGGAAGAAAGAATTACAACCCTTGAAAAGCGTTACCTCA
GTGCTCAGAGAGAATCTACCTCCATACATGACATGAATGATAAACTAGAAAATGAGTTAGCAAATAAAGAAGCTATCCTGCGGCAGATGG
AAGAGAAAAACAGACAGTTACAAGAACGTCTTGAGCTAGCTGAACAAAAGTTGCAGCAGACCATGAGAAAGGCTGAAACCTTGCCTGAAG
TAGAGGCTGAACTGGCTCAGAGAATTGCAGCCCTAACCAAGGCTGAAGAGAGACATGGAAATATTGAAGAACGTATGAGACATTTAGAGG
GTCAACTTGAAGAGAAGAATCAAGAACTTCAAAGAGCTAGGCAAAGAGAGAAAATGAATGAGGAGCATAACAAGAGATTATCGGATACGG
TTGATAGACTTCTGACTGAATCCAATGAACGCCTACAACTACACTTAAAGGAAAGAATGGCTGCTCTAGAAGAAAAGAATGTTTTAATTC
AAGAATCAGAAACTTTCAGAAAGAATCTTGAAGAATCTTTACATGATAAGGAAAGATTAGCAGAAGAAATTGAAAAGCTGAGATCTGAAC
TTGACCAATTGAAAATGAGAACTGGCTCTTTAATTGAACCCACAATACCAAGAACTCATCTAGACACCTCAGCTGAGTTGCGGTACTCAG
TGGGATCCCTAGTGGACAGCCAGTCTGATTACAGAACAACTAAAGTAATAAGAAGACCAAGGAGAGGCCGCATGGGTGTGCGAAGAGATG
AGCCAAAGGTGAAATCTCTTGGGGATCACGAGTGGAATAGAACTCAACAGATTGGAGTACTAAGCAGCCACCCTTTTGAAAGTGACACTG
AAATGTCTGATATTGATGATGATGACAGAGAAACAATTTTTAGCTCAATGGATCTTCTCTCTCCAAGTGGTCATTCCGATGCCCAGACGC
TAGCCATGATGCTTCAGGAACAATTGGATGCCATCAACAAAGAAATCAGGCTAATTCAGGAAGAAAAAGAATCTACAGAGTTGCGTGCTG
AAGAAATTGAAAATAGAGTGGCTAGTGTGAGCCTCGAAGGCCTGAATTTGGCAAGGGTCCACCCAGGTACCTCCATTACTGCCTCTGTTA
CAGCTTCATCGCTGGCCAGTTCATCTCCCCCCAGTGGACACTCAACTCCAAAGCTCACCCCTCGAAGCCCTGCCAGGGAAATGGATCGGA
TGGGAGTCATGACACTGCCAAGTGATCTGAGGAAACATCGGAGAAAGATTGCAGTTGTGGAAGAAGATGGTCGAGAGGACAAAGCAACAA
TTAAATGTGAAACTTCTCCTCCTCCTACCCCTAGAGCCCTCAGAATGACTCACACTCTCCCTTCTTCCTACCACAATGATGCTCGAAGTA
GTTTATCTGTCTCTCTTGAGCCAGAAAGCCTCGGGCTTGGTAGTGCCAACAGCAGCCAAGACTCTCTTCACAAAGCCCCCAAGAAGAAAG
GAATCAAGTCTTCAATAGGACGTTTGTTTGGTAAAAAAGAAAAAGCTCGACTTGGGCAGCTCCGAGGCTTTATGGAGACTGAAGCTGCAG
CTCAGGAGTCCCTGGGGTTAGGCAAACTCGGAACTCAAGCTGAGAAGGATCGAAGACTAAAGAAAAAGCATGAACTTCTTGAAGAAGCTC
GGAGAAAGGGATTACCTTTTGCCCAGTGGGATGGGCCAACTGTGGTCGCATGGCTAGAGCTTTGGTTGGGAATGCCTGCGTGGTACGTGG
CAGCCTGCCGAGCCAACGTGAAGAGTGGTGCCATCATGTCTGCTTTATCTGACACTGAGATCCAGAGAGAAATTGGAATCAGCAATCCAC
TGCATCGCTTAAAACTTCGATTAGCAATCCAGGAGATGGTTTCCCTAACAAGTCCTTCAGCTCCTCCAACATCTCGAACTCCTTCAGGCA
ACGTTTGGGTGACTCATGAAGAAATGGAAAATCTTGCAGCTCCAGCAAAAACGAAAGAATCTGAGGAAGGAAGCTGGGCCCAGTGTCCGG
TTTTTCTACAGACCCTGGCTTATGGAGATATGAATCATGAGTGGATTGGAAATGAATGGCTTCCCAGCTTGGGGTTACCTCAGTACAGAA
GTTACTTTATGGAATGCTTGGTAGATGCAAGAATGTTAGATCACCTAACAAAAAAAGATCTCCGTGTCCATTTAAAAATGGTGGATAGTT
TCCATCGAACAAGTTTACAATATGGAATTATGTGCTTAAAGAGGTTGAATTATGACAGAAAAGAACTAGAAAGAAGACGGGAAGCAAGCC
AACATGAAATAAAAGACGTGTTGGTGTGGAGCAATGACCGAGTTATTCGCTGGATACAAGCAATTGGACTTCGAGAATATGCAAATAATA
TACTTGAGAGCGGTGTGCATGGCTCACTTATAGCCCTGGATGAAAACTTTGACTACAGCAGCTTAGCTTTATTATTACAGATTCCAACAC
AGAACACCCAGGCAAGGCAGATTCTTGAAAGAGAATACAATAACCTCTTGGCCCTGGGAACTGAAAGGCGACTGGATGAAAGTGATGACA
AGAACTTCAGACGTGGATCAACCTGGAGAAGGCAGTTTCCTCCTCGTGAAGTACATGGAATCAGCATGATGCCTGGGTCCTCAGAAACAT
TACCAGCTGGATTTAGGTTAACCACAACCTCTGGGCAGTCAAGAAAAATGACAACAGATGTTGCTTCATCAAGACTGCAGAGGTTAGACA
ACTCCACTGTTCGCACATACTCATGTTGACCAGCCACTCAAAGGAGGCAGCACTGACCTGCTATGGCGTCTTTTCAGTCTACTCTACCTA
AAGTGCACTACCATCTAAGAAGACGAGCAGTGAAAACCTTTGTGAAAACTGAATTCTAAGGAAATAATGACGTCATGACTTATTAAAAGC
TGAAAAATGTGATTTTTGGGGGGAGTCAGATATTACATTTGATTAGTTTACTACAAATTGTAATAAAATGCTTAAGTCATTTGAATAATA
AACATCATCTACATCATAAACTCTGTACAACAGATGCTTTTATGAAATGAAGCCAGTTGTTTTTCATGTTTTATTGTAATATACTAGGCA
TTTATGTATTACCGTGCATTTCTTTTTAAATGTGTAAGTCTTATGTAAATGGATATAAATATGATTTTTTAAAAAATAAAATATATGGTT
CATGGAGTCTCGAGTGCAAACATTTGACAATTCCAAGTACTGTTTGTATTTTACCATTCCACCATTTTTACAGTTTTTGGATTGTTAATA
GTCAAATCAATATGTTTCCTTGAAGCATGTTTCATGCTTCAACGTGTTTCTCCTTCAAGTCTGTCAATACTTAAAGCTGAACAACCTGCC
TCTGATCATGTAAAAAAGAATGATTTAACCTGGAACCGGAGCCAAAAATAGAGCTTTAAAGGCAATCAGGGATGTCCTATATCTTTAGAA
ATAGCACTGTGATGGCTTGATCTCCTTTTCAATACAAAACAAAGCCAAGCTGTTTACAAGGGTCAAAAGCAATTATTTAAAAATTTATAT
TAAAAAACCATAATCTTCTCTTGTTACCTGTGGACCAAGAAAAAAAAAAAGATAAAAAAACTTCTTTACTAAGAACCACATGTTCATTCA
AATATCTTGAAATGCCAGCCAGTACTGGACAGTGAATGTCAACCACCGCAGAGTCTGAGGCTCATTTCCACTAGAGAAAACGAAACCCAA
GATACCTTTCCCTTTTGTCAATGTAACAGGGCATTAGCCAGACTCATGTCTAATGTTATAAGCTTTTAGCCGAGATGGCCTTGTTGCGAC
TTCCCTGAAGTCAGTTTTATCAGAGGAAATAAATGAAAGACAGAATGATTAACATATATAGTGTATAAAAGTATAGAAGAGTAATCTCTT
CCCTGTGGCTTTATTTGGTGGTGTTACTGTTGTTTATTCTTTGTTTATATGGGAGATTCAAAGTAAAGCCTATTTAATAATACCATTTAT
CTAACTGCTGATTTTCTGCTGCTTGATCTTATTAAGCGCAAGACCTGTCATTAGTAATTTCTTTTCTGTATTTTAATTTGCTATGTTTGC
ACGTACATTACATTTGTTTTGATGTCTATTTTTATTTAACAGATTCAGTCAAAAGGTAATGATAACAGAAACCCTTTCCATTGTCAATAA

>92517_92517_2_TMTC2-PPFIA2_TMTC2_chr12_83455610_ENST00000321196_PPFIA2_chr12_81851645_ENST00000549396_length(amino acids)=1952AA_BP=796
MLPLLPSRWEPSRREGGGEMIAELVSSALGLALYLNTLSADFCYDDSRAIKTNQDLLPETPWTHIFYNDFWGTLLTHSGSHKSYRPLCTL
SFRLNHAIGGLNPWSYHLVNVLLHAAVTGLFTSFSKILLGDGYWTFMAGLMFASHPIHTEAVAGIVGRADVGASLFFLLSLLCYIKHCST
RGYSARTWGWFLGSGLCAGCSMLWKEQGVTVLAVSAVYDVFVFHRLKIKQILPTIYKRKNLSLFLSISLLIFWGSSLLGARLYWMGNKPP
SFSNSDNPAADSDSLLTRTLTFFYLPTKNLWLLLCPDTLSFDWSMDAVPLLKTVCDWRNLHTVAFYTGLLLLAYYGLKSPSVDRECNGKT
VTNGKQNANGHSCLSDVEYQNSETKSSFASKVENGIKNDVSQRTQLPSTENIVVLSLSLLIIPFVPATNLFFYVGFVIAERVLYIPSMGF
CLLITVGARALYVKVQKRFLKSLIFYATATLIVFYGLKTAIRNGDWQNEEMLYRSGIKVNPAKAWGNLGNVLKSQSKISEAESAYRNALY
YRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIPDENLKDPHAHKSSVTSCLYN
LGKLYHEQGHYEEALSVYKEAIQKMPRQFAPQSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKLFL
KAIELDPTKGNCYMHYGQFLLEEARLIEAAEMAKKAAELDSTEFDVVFNAAHMLRQASLNEAAEKYYDLAARLRPNEFAALTKELNACRE
QLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSAL
EEELAAANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALS
SRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQL
QERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTE
SNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIPRTHLDTSAELRYSVGSLVDS
QSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQE
QLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLP
SDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRALRMTHTLPSSYHNDARSSLSVSLEPESLGLGSANSSQDSLHKAPKKKGIKSSIG
RLFGKKEKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANV
KSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTKESEEGSWAQCPVFLQTLA
YGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDV
LVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDESDDKNFRRGS

--------------------------------------------------------------
>92517_92517_3_TMTC2-PPFIA2_TMTC2_chr12_83455610_ENST00000321196_PPFIA2_chr12_81851645_ENST00000550584_length(transcript)=7844nt_BP=3038nt
GTCACGCAGGCGCGGGGGGCCGCGTCGAGAACCCCACGCGGGAGCTTCTGGAGTCTCCAGCCACCGCTTCTCACTTCACTGGAGAAGGGA
GCTGGGGCTGGGGCTGGGGCTGGGGCTGGGAGGGAGCTAATAAACATTGAATGTGCAGCAGCTGCCTTGGCGGCCGGAGTCCGCCCGAGC
GACACCGGAGCAGTGCGCCCGGGAGGCGGCGAGGGGAGGCGGTTCGCCTTGTCCCTCCCACCCGCGCCTCTTTCTCTCTCTTCCTCCAGC
TGGTCCCAGAGCCCGGCTTGGTCCGGTCCCTCTGCCCCCATCCCGCACCCTTCCACCTCCTCCGAGTCCCACTCCTCACCTAGGACGCCC
CAAACTGCCATGGGTTAGGGTGGGGATCGCGACCCGCGCGAAAGACCAGCCCTGCGCTTCCGCCGGGGGACGCGGAGCCCAAACGCCGCT
CACCGCTTGCGGGCGCCGGGCATGGGGAGTGTGGTGTGAGCCCGCACCCGGGGAGGACGCAGGAGCTGCGGAGACGGGCGCGAGGAGGAG
GAGAGGAGTCGTGGATTGGAAGGACCCGAGGGAGGGAGGGTGGGGAAGCGAGGGAAAAGTGAAGCTGGGAGGAGAAGGCGGCGGAAGGTG
GAGATTGATGCTTCTGTTTTTTGTTGCCGCTGCTGCCCTCGCGCTGGGAGCCGAGCCGGAGGGAAGGCGGTGGAGAGATGATTGCAGAGT
TGGTGAGCAGCGCTCTGGGGCTCGCCTTGTATCTCAACACCCTGAGTGCGGATTTCTGCTATGATGACAGCCGTGCTATCAAGACTAATC
AGGACCTTCTCCCAGAAACTCCATGGACGCACATTTTCTACAATGATTTTTGGGGGACTCTTCTAACCCACAGTGGCAGCCACAAGTCCT
ACCGGCCACTCTGCACTCTTTCTTTTCGCCTGAACCATGCCATTGGAGGGTTGAATCCCTGGAGCTACCATCTTGTCAATGTCCTGTTGC
ATGCAGCAGTCACTGGTCTCTTCACAAGCTTCTCCAAGATCCTCCTTGGTGATGGATACTGGACATTCATGGCTGGCTTGATGTTTGCTT
CTCACCCCATTCACACGGAGGCAGTGGCAGGAATCGTGGGACGAGCCGATGTCGGGGCCAGTCTCTTCTTTCTCCTCTCCTTGCTCTGCT
ACATTAAACACTGTTCTACAAGAGGCTACTCAGCCAGAACCTGGGGCTGGTTCCTGGGGTCAGGACTGTGCGCAGGATGCAGCATGTTGT
GGAAGGAACAAGGAGTGACTGTTCTCGCAGTTTCAGCAGTTTATGATGTCTTTGTCTTTCACAGGCTGAAAATAAAACAGATATTACCTA
CCATTTACAAAAGGAAGAACTTGTCGCTTTTCCTAAGCATTAGTTTGTTAATTTTCTGGGGTTCCTCCCTTTTGGGTGCCCGGTTATACT
GGATGGGAAACAAACCACCAAGCTTTTCCAACTCGGACAACCCCGCTGCTGATTCGGACAGCCTCCTCACCCGCACTCTCACCTTCTTCT
ACTTGCCAACCAAGAACCTCTGGCTGTTGCTATGTCCAGATACCCTCAGTTTTGATTGGTCAATGGATGCTGTGCCTCTGCTCAAAACAG
TTTGTGACTGGAGAAACCTACACACTGTGGCCTTCTATACTGGACTCCTTCTCCTTGCCTACTATGGTTTGAAGAGCCCGAGCGTAGACA
GAGAATGCAATGGGAAAACTGTAACAAATGGCAAGCAGAATGCAAATGGACATAGCTGCCTTTCAGATGTGGAGTACCAGAACTCAGAGA
CTAAGTCCAGCTTTGCATCCAAAGTAGAAAATGGCATTAAAAACGATGTATCACAGAGAACCCAGCTTCCTTCTACGGAGAACATTGTTG
TTCTGTCTTTATCTTTGTTAATCATACCCTTTGTTCCTGCCACGAACCTGTTTTTCTATGTCGGCTTTGTAATTGCAGAGCGAGTATTAT
ATATTCCTAGTATGGGCTTCTGCCTACTGATTACAGTGGGTGCTAGAGCCCTTTATGTCAAAGTCCAAAAGCGGTTCCTCAAGAGCTTGA
TTTTTTATGCTACAGCTACACTAATTGTTTTTTATGGACTCAAGACTGCGATCAGGAATGGAGACTGGCAGAATGAGGAAATGCTTTATA
GATCAGGGATAAAAGTAAACCCAGCTAAAGCATGGGGTAACCTTGGAAATGTTCTGAAGAGTCAGAGCAAAATTTCTGAAGCTGAAAGCG
CCTATAGAAATGCTTTGTACTACCGCAGCAACATGGCTGACATGCTTTATAATTTAGGGCTACTTCTCCAGGAGAACAGCAGGTTTGCAG
AAGCACTACATTATTATAAATTGGCCATTGGGAGCAGGCCTACCCTGGCTTCTGCATATTTAAATACCGGTATTATTCTAATGAACCAAG
GAAGGACGGAAGAAGCCCGACGGACATTCTTAAAGTGTTCGGAGATCCCAGATGAAAACCTAAAGGACCCTCATGCACACAAGAGCTCTG
TTACCAGTTGTTTGTACAACCTAGGAAAGCTGTATCATGAGCAGGGACACTATGAGGAAGCCCTTAGTGTATACAAGGAAGCAATTCAGA
AAATGCCAAGGCAGTTTGCCCCACAGAGCTTGTACAACATGATGGGTGAAGCATATATGCGTTTAAGCAAACTCCCCGAAGCAGAGCATT
GGTATATGGAATCACTGAGATCCAAGACTGACCACATCCCTGCTCATCTCACCTATGGGAAGCTGCTAGCTCTAACAGGTCGTAAGAGTG
AGGCTGAAAAGCTCTTCTTGAAGGCTATTGAGCTGGATCCCACCAAAGGAAACTGTTACATGCATTATGGTCAGTTTCTTCTGGAAGAAG
CTCGTCTCATAGAAGCAGCTGAGATGGCAAAAAAAGCAGCTGAACTAGACAGCACAGAGTTTGATGTTGTCTTCAATGCTGCCCACATGC
TCAGACAGGCTAGCCTCAATGAAGCAGCTGAGAAGTATTATGATCTGGCAGCCAGGCTGAGGCCTAATGAATTTGCTGCACTGACAAAAG
AATTAAATGCCTGCAGGGAACAACTTCTAGAAAAGGAAGAAGAAATCTCTGAACTTAAAGCTGAAAGAAACAACACAAGACTATTACTGG
AGCATTTGGAGTGCCTTGTGTCACGACATGAAAGATCACTAAGAATGACGGTGGTAAAACGGCAAGCCCAGTCTCCCTCAGGAGTATCCA
GTGAAGTTGAAGTTCTCAAGGCACTGAAATCTTTGTTTGAGCACCACAAGGCCTTGGATGAAAAGGTAAGGGAGCGACTGAGGGTTTCTT
TAGAAAGAGTCTCTGCACTGGAAGAAGAACTAGCTGCTGCTAATCAGGAGATTGTTGCCTTGCGTGAACAAAATGTTCATATACAAAGAA
AAATGGCATCAAGCGAGGGATCCACAGAGTCAGAACATCTTGAAGGGATGGAACCTGGACAGAAAGTCCATGAGAAGCGTTTGTCCAATG
GTTCTATAGACTCAACCGATGAAACTAGTCAAATAGTTGAACTACAAGAATTGCTTGAAAAGCAAAACTATGAAATGGCCCAGATGAAAG
AACGTTTAGCAGCCCTTTCTTCCCGAGTGGGAGAGGTGGAACAGGAAGCAGAGACAGCAAGAAAGGATCTCATTAAAACAGAAGAAATGA
ACACCAAGTATCAAAGGGACATTAGGGAGGCCATGGCACAAAAGGAAGATATGGAAGAAAGAATTACAACCCTTGAAAAGCGTTACCTCA
GTGCTCAGAGAGAATCTACCTCCATACATGACATGAATGATAAACTAGAAAATGAGTTAGCAAATAAAGAAGCTATCCTGCGGCAGATGG
AAGAGAAAAACAGACAGTTACAAGAACGTCTTGAGCTAGCTGAACAAAAGTTGCAGCAGACCATGAGAAAGGCTGAAACCTTGCCTGAAG
TAGAGGCTGAACTGGCTCAGAGAATTGCAGCCCTAACCAAGGCTGAAGAGAGACATGGAAATATTGAAGAACGTATGAGACATTTAGAGG
GTCAACTTGAAGAGAAGAATCAAGAACTTCAAAGAGCTAGGCAAAGAGAGAAAATGAATGAGGAGCATAACAAGAGATTATCGGATACGG
TTGATAGACTTCTGACTGAATCCAATGAACGCCTACAACTACACTTAAAGGAAAGAATGGCTGCTCTAGAAGAAAAGAATGTTTTAATTC
AAGAATCAGAAACTTTCAGAAAGAATCTTGAAGAATCTTTACATGATAAGGAAAGATTAGCAGAAGAAATTGAAAAGCTGAGATCTGAAC
TTGACCAATTGAAAATGAGAACTGGCTCTTTAATTGAACCCACAATACCAAGAACTCATCTAGACACCTCAGCTGAGTTGCGGTACTCAG
TGGGATCCCTAGTGGACAGCCAGTCTGATTACAGAACAACTAAAGTAATAAGAAGACCAAGGAGAGGCCGCATGGGTGTGCGAAGAGATG
AGCCAAAGGTGAAATCTCTTGGGGATCACGAGTGGAATAGAACTCAACAGATTGGAGTACTAAGCAGCCACCCTTTTGAAAGTGACACTG
AAATGTCTGATATTGATGATGATGACAGAGAAACAATTTTTAGCTCAATGGATCTTCTCTCTCCAAGTGGTCATTCCGATGCCCAGACGC
TAGCCATGATGCTTCAGGAACAATTGGATGCCATCAACAAAGAAATCAGGCTAATTCAGGAAGAAAAAGAATCTACAGAGTTGCGTGCTG
AAGAAATTGAAAATAGAGTGGCTAGTGTGAGCCTCGAAGGCCTGAATTTGGCAAGGGTCCACCCAGGTACCTCCATTACTGCCTCTGTTA
CAGCTTCATCGCTGGCCAGTTCATCTCCCCCCAGTGGACACTCAACTCCAAAGCTCACCCCTCGAAGCCCTGCCAGGGAAATGGATCGGA
TGGGAGTCATGACACTGCCAAGTGATCTGAGGAAACATCGGAGAAAGATTGCAGTTGTGGAAGAAGATGGTCGAGAGGACAAAGCAACAA
TTAAATGTGAAACTTCTCCTCCTCCTACCCCTAGAGCCCTCAGAATGACTCACACTCTCCCTTCTTCCTACCACAATGATGCTCGAAGTA
GTTTATCTGTCTCTCTTGAGCCAGAAAGCCTCGGGCTTGGTAGTGCCAACAGCAGCCAAGACTCTCTTCACAAAGCCCCCAAGAAGAAAG
GAATCAAGTCTTCAATAGGACGTTTGTTTGGTAAAAAAGAAAAAGCTCGACTTGGGCAGCTCCGAGGCTTTATGGAGACTGAAGCTGCAG
CTCAGGAGTCCCTGGGGTTAGGCAAACTCGGAACTCAAGCTGAGAAGGATCGAAGACTAAAGAAAAAGCATGAACTTCTTGAAGAAGCTC
GGAGAAAGGGATTACCTTTTGCCCAGTGGGATGGGCCAACTGTGGTCGCATGGCTAGAGCTTTGGTTGGGAATGCCTGCGTGGTACGTGG
CAGCCTGCCGAGCCAACGTGAAGAGTGGTGCCATCATGTCTGCTTTATCTGACACTGAGATCCAGAGAGAAATTGGAATCAGCAATCCAC
TGCATCGCTTAAAACTTCGATTAGCAATCCAGGAGATGGTTTCCCTAACAAGTCCTTCAGCTCCTCCAACATCTCGAACTCCTTCAGGCA
ACGTTTGGGTGACTCATGAAGAAATGGAAAATCTTGCAGCTCCAGCAAAAACGAAAGAATCTGAGGAAGGAAGCTGGGCCCAGTGTCCGG
TTTTTCTACAGACCCTGGCTTATGGAGATATGAATCATGAGTGGATTGGAAATGAATGGCTTCCCAGCTTGGGGTTACCTCAGTACAGAA
GTTACTTTATGGAATGCTTGGTAGATGCAAGAATGTTAGATCACCTAACAAAAAAAGATCTCCGTGTCCATTTAAAAATGGTGGATAGTT
TCCATCGAACAAGTTTACAATATGGAATTATGTGCTTAAAGAGGTTGAATTATGACAGAAAAGAACTAGAAAGAAGACGGGAAGCAAGCC
AACATGAAATAAAAGACGTGTTGGTGTGGAGCAATGACCGAGTTATTCGCTGGATACAAGCAATTGGACTTCGAGAATATGCAAATAATA
TACTTGAGAGCGGTGTGCATGGCTCACTTATAGCCCTGGATGAAAACTTTGACTACAGCAGCTTAGCTTTATTATTACAGATTCCAACAC
AGAACACCCAGGCAAGGCAGATTCTTGAAAGAGAATACAATAACCTCTTGGCCCTGGGAACTGAAAGGCGACTGGATGAAAGTGATGACA
AGAACTTCAGACGTGGATCAACCTGGAGAAGGCAGTTTCCTCCTCGTGAAGTACATGGAATCAGCATGATGCCTGGGTCCTCAGAAACAT
TACCAGCTGGATTTAGGTTAACCACAACCTCTGGGCAGTCAAGAAAAATGACAACAGATGATGGCGTCTTTTCAGTCTACTCTACCTAAA
GTGCACTACCATCTAAGAAGACGAGCAGTGAAAACCTTTGTGAAAACTGAATTCTAAGGAAATAATGACGTCATGACTTATTAAAAGCTG
AAAAATGTGATTTTTGGGGGGAGTCAGATATTACATTTGATTAGTTTACTACAAATTGTAATAAAATGCTTAAGTCATTTGAATAATAAA
CATCATCTACATCATAAACTCTGTACAACAGATGCTTTTATGAAATGAAGCCAGTTGTTTTTCATGTTTTATTGTAATATACTAGGCATT
TATGTATTACCGTGCATTTCTTTTTAAATGTGTAAGTCTTATGTAAATGGATATAAATATGATTTTTTAAAAAATAAAATATATGGTTCA
TGGAGTCTCGAGTGCAAACATTTGACAATTCCAAGTACTGTTTGTATTTTACCATTCCACCATTTTTACAGTTTTTGGATTGTTAATAGT
CAAATCAATATGTTTCCTTGAAGCATGTTTCATGCTTCAACGTGTTTCTCCTTCAAGTCTGTCAATACTTAAAGCTGAACAACCTGCCTC
TGATCATGTAAAAAAGAATGATTTAACCTGGAACCGGAGCCAAAAATAGAGCTTTAAAGGCAATCAGGGATGTCCTATATCTTTAGAAAT
AGCACTGTGATGGCTTGATCTCCTTTTCAATACAAAACAAAGCCAAGCTGTTTACAAGGGTCAAAAGCAATTATTTAAAAATTTATATTA
AAAAACCATAATCTTCTCTTGTTACCTGTGGACCAAGAAAAAAAAAAAGATAAAAAAACTTCTTTACTAAGAACCACATGTTCATTCAAA
TATCTTGAAATGCCAGCCAGTACTGGACAGTGAATGTCAACCACCGCAGAGTCTGAGGCTCATTTCCACTAGAGAAAACGAAACCCAAGA
TACCTTTCCCTTTTGTCAATGTAACAGGGCATTAGCCAGACTCATGTCTAATGTTATAAGCTTTTAGCCGAGATGGCCTTGTTGCGACTT
CCCTGAAGTCAGTTTTATCAGAGGAAATAAATGAAAGACAGAATGATTAACATATATAGTGTATAAAAGTATAGAAGAGTAATCTCTTCC
CTGTGGCTTTATTTGGTGGTGTTACTGTTGTTTATTCTTTGTTTATATGGGAGATTCAAAGTAAAGCCTATTTAATAATACCATTTATCT
AACTGCTGATTTTCTGCTGCTTGATCTTATTAAGCGCAAGACCTGTCATTAGTAATTTCTTTTCTGTATTTTAATTTGCTATGTTTGCAC
GTACATTACATTTGTTTTGATGTCTATTTTTATTTAACAGATTCAGTCAAAAGGTAATGATAACAGAAACCCTTTCCATTGTCAATAAAA

>92517_92517_3_TMTC2-PPFIA2_TMTC2_chr12_83455610_ENST00000321196_PPFIA2_chr12_81851645_ENST00000550584_length(amino acids)=1942AA_BP=796
MLPLLPSRWEPSRREGGGEMIAELVSSALGLALYLNTLSADFCYDDSRAIKTNQDLLPETPWTHIFYNDFWGTLLTHSGSHKSYRPLCTL
SFRLNHAIGGLNPWSYHLVNVLLHAAVTGLFTSFSKILLGDGYWTFMAGLMFASHPIHTEAVAGIVGRADVGASLFFLLSLLCYIKHCST
RGYSARTWGWFLGSGLCAGCSMLWKEQGVTVLAVSAVYDVFVFHRLKIKQILPTIYKRKNLSLFLSISLLIFWGSSLLGARLYWMGNKPP
SFSNSDNPAADSDSLLTRTLTFFYLPTKNLWLLLCPDTLSFDWSMDAVPLLKTVCDWRNLHTVAFYTGLLLLAYYGLKSPSVDRECNGKT
VTNGKQNANGHSCLSDVEYQNSETKSSFASKVENGIKNDVSQRTQLPSTENIVVLSLSLLIIPFVPATNLFFYVGFVIAERVLYIPSMGF
CLLITVGARALYVKVQKRFLKSLIFYATATLIVFYGLKTAIRNGDWQNEEMLYRSGIKVNPAKAWGNLGNVLKSQSKISEAESAYRNALY
YRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIPDENLKDPHAHKSSVTSCLYN
LGKLYHEQGHYEEALSVYKEAIQKMPRQFAPQSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKLFL
KAIELDPTKGNCYMHYGQFLLEEARLIEAAEMAKKAAELDSTEFDVVFNAAHMLRQASLNEAAEKYYDLAARLRPNEFAALTKELNACRE
QLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSAL
EEELAAANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALS
SRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQL
QERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTE
SNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIPRTHLDTSAELRYSVGSLVDS
QSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQE
QLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLP
SDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRALRMTHTLPSSYHNDARSSLSVSLEPESLGLGSANSSQDSLHKAPKKKGIKSSIG
RLFGKKEKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANV
KSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTKESEEGSWAQCPVFLQTLA
YGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDV
LVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDESDDKNFRRGS

--------------------------------------------------------------
>92517_92517_4_TMTC2-PPFIA2_TMTC2_chr12_83455610_ENST00000549919_PPFIA2_chr12_81851645_ENST00000549325_length(transcript)=8323nt_BP=4118nt
TCTAGAGTTATCAATCTGAATTATAAATTTTGTAAAATTATTCACAAAAGCACTTATTTTGTAAGTGTAGTGTAGAATGTTAGATGTATG
ACCTATAATTAATTCCATTAATCCTCAAATAAAACTGTGGAATCATTTTCCTTTCAAACAGCAGTTTAAATTCAAACTGTATTACCATTA
GCATAAGAATAGCTTTTAACAATAATTAAAATCCTAATGGTATCATGAAATAATTTTAGTTTAGTTATCCTTTTGATGTAAATATTTATC
CAGTGGGAGAACCTGATTTGTTAAACATTTTATATGAATTTGATTTGAGAAATGCACAGCACCATATAAATATATCACTGTAGGAGGCAG
TGTAGCCATAAGGAAAACATACCGGATTGAGTGTCAAGAACTGGTGTCTGTATGGTGCTGTACTGCACAAGCTTCATATGACCTTAATTT
CCGAGCATCAGTTTCATCATTGGTTAAAAAAAAAGAGATGACAGTATCAGACTTGCCTCACGGCTGTCTGCCAATTAAGTGAATTAGAAA
ATTATTTTCAATTATATAGTGCTGGGCAAGGTGAATGATTGCTATTACTGTTGTCATCACTGTTGTTTGAAGCACTGTGCTTTGGGAAGC
AAATCTGGTTCACATCTTTTGAACATTTAAATGAAGAGAATGTGTCTCAGTGCTCTAGTGTGTATTAAAACAGCCTTTTAACAAGAATGT
TTTGAACCCTGCCCAATACCTGCACATGCTTTTGTTAATACTTCATTACATAAAATGACCAAGAAGCTGTCATAAGAATTTAAAGGAACA
TTTACCCTCATCTTTAAAATGTATCTTAAAAGAGAGATAAGATTCTAATTACAAATTTTGAACAGTTTATTTTCTCTCTATGAAAAATTT
CCAAGAATGATACAAAAGCACTTTTATGTGAAGAGGATACACTGGAACATTGAGGTCTTGATCTCATTTTAGTAACTCTCTGATGTGATT
AATTCATAAGCACTGAGTTGTAGCTCATTCCTTCTGGCAAAATTCCAGCACTTGATTGTTACCTTATAAACTTTTAATAAGAGTAATTTT
AAAAACTGCACTTGACTCTTGCTTTATGAAAAGCTGGAAATGTAAAAAGTTAAAAATGCTTGACAATTTTTCTGAGCTCTAGTCAGAAAC
AGTGGCTATGCCCTTTTATAGATGACAGCCCAAAGGCGAGTTTGTAAAACGATAAATAAATTGTAAAGATCTATCGAGTGGCAACTTGGA
TGGTTTAATGCCTATGGGTTAGAAACCCAGGAGTTAATGTTTAAAGTGATTTGGATAAATGTGAACATGTTTAAATCTTTAGTATTATTC
CTTTAAGCCAAATGTGAACGATAGTTATTTTGACAAAGTTTGGGTTACCTCGATAGCCTGATTTTTACAGAAGTACCGTGTATCTCAAAT
TGTTAACTGATGAATGGGTGGTGCTGCTGGATTATTTCCTGTGTTTTGTGTTTTTCTTAGTTTTAATTTCTTTGTTATTCAAGTTATACT
ATCACCTCGTCCAAAGTTGGGTCTCAGGATTAGATTAATAAACTAACCAAGTAAATTTGGGAAGTATGACTAACTTACATAAAGAAAATA
ATTGGGGTTATTTTTTTGTATTATTATTTTAAAATATGTAATCAGCACTTTTGAGAAGCTCTCATTTTGTTGAATCTCTAGGCAGACCTT
TGTGGTTAAGCATCATCCTGGAAATTTTTTCTGACAGTCATTTGACCAGGTCTTTCTGTTTATACTCAGTGTCAAAACAACAACAACAAA
AATGCATGGAACCATCTAGTTGCAGGAAAACAAGCTCAGGACTCAGGACTCCCACTGATTATACATTATGCCGTGCTATCAAGACTAATC
AGGACCTTCTCCCAGAAACTCCATGGACGCACATTTTCTACAATGATTTTTGGGGGACTCTTCTAACCCACAGTGGCAGCCACAAGTCCT
ACCGGCCACTCTGCACTCTTTCTTTTCGCCTGAACCATGCCATTGGAGGGTTGAATCCCTGGAGCTACCATCTTGTCAATGTCCTGTTGC
ATGCAGCAGTCACTGGTCTCTTCACAAGCTTCTCCAAGATCCTCCTTGGTGATGGATACTGGACATTCATGGCTGGCTTGATGTTTGCTT
CTCACCCCATTCACACGGAGGCAGTGGCAGGAATCGTGGGACGAGCCGATGTCGGGGCCAGTCTCTTCTTTCTCCTCTCCTTGCTCTGCT
ACATTAAACACTGTTCTACAAGAGGCTACTCAGCCAGAACCTGGGGCTGGTTCCTGGGGTCAGGACTGTGCGCAGGATGCAGCATGTTGT
GGAAGGAACAAGGAGTGACTGTTCTCGCAGTTTCAGCAGTTTATGATGTCTTTGTCTTTCACAGGCTGAAAATAAAACAGATATTACCTA
CCATTTACAAAAGGAAGAACTTGTCGCTTTTCCTAAGCATTAGTTTGTTAATTTTCTGGGGTTCCTCCCTTTTGGGTGCCCGGTTATACT
GGATGGGAAACAAACCACCAAGCTTTTCCAACTCGGACAACCCCGCTGCTGATTCGGACAGCCTCCTCACCCGCACTCTCACCTTCTTCT
ACTTGCCAACCAAGAACCTCTGGCTGTTGCTATGTCCAGATACCCTCAGTTTTGATTGGTCAATGGATGCTGTGCCTCTGCTCAAAACAG
TTTGTGACTGGAGAAACCTACACACTGTGGCCTTCTATACTGGACTCCTTCTCCTTGCCTACTATGGTTTGAAGAGCCCGAGCGTAGACA
GAGAATGCAATGGGAAAACTGTAACAAATGGCAAGCAGAATGCAAATGGACATAGCTGCCTTTCAGATGTGGAGTACCAGAACTCAGAGA
CTAAGTCCAGCTTTGCATCCAAAGTAGAAAATGGCATTAAAAACGATGTATCACAGAGAACCCAGCTTCCTTCTACGGAGAACATTGTTG
TTCTGTCTTTATCTTTGTTAATCATACCCTTTGTTCCTGCCACGAACCTGTTTTTCTATGTCGGCTTTGTAATTGCAGAGCGAGTATTAT
ATATTCCTAGTATGGGCTTCTGCCTACTGATTACAGTGGGTGCTAGAGCCCTTTATGTCAAAGTCCAAAAGCGGTTCCTCAAGAGCTTGA
TTTTTTATGCTACAGCTACACTAATTGTTTTTTATGGACTCAAGACTGCGATCAGGAATGGAGACTGGCAGAATGAGGAAATGCTTTATA
GATCAGGGATAAAAGTAAACCCAGCTAAAGCATGGGGTAACCTTGGAAATGTTCTGAAGAGTCAGAGCAAAATTTCTGAAGCTGAAAGCG
CCTATAGAAATGCTTTGTACTACCGCAGCAACATGGCTGACATGCTTTATAATTTAGGGCTACTTCTCCAGGAGAACAGCAGGTTTGCAG
AAGCACTACATTATTATAAATTGGCCATTGGGAGCAGGCCTACCCTGGCTTCTGCATATTTAAATACCGGTATTATTCTAATGAACCAAG
GAAGGACGGAAGAAGCCCGACGGACATTCTTAAAGTGTTCGGAGATCCCAGATGAAAACCTAAAGGACCCTCATGCACACAAGAGCTCTG
TTACCAGTTGTTTGTACAACCTAGGAAAGCTGTATCATGAGCAGGGACACTATGAGGAAGCCCTTAGTGTATACAAGGAAGCAATTCAGA
AAATGCCAAGGCAGTTTGCCCCACAGAGCTTGTACAACATGATGGGTGAAGCATATATGCGTTTAAGCAAACTCCCCGAAGCAGAGCATT
GGTATATGGAATCACTGAGATCCAAGACTGACCACATCCCTGCTCATCTCACCTATGGGAAGCTGCTAGCTCTAACAGGTCGTAAGAGTG
AGGCTGAAAAGCTCTTCTTGAAGGCTATTGAGCTGGATCCCACCAAAGGAAACTGTTACATGCATTATGGTCAGTTTCTTCTGGAAGAAG
CTCGTCTCATAGAAGCAGCTGAGATGGCAAAAAAAGCAGCTGAACTAGACAGCACAGAGTTTGATGTTGTCTTCAATGCTGCCCACATGC
TCAGACAGGCTAGCCTCAATGAAGCAGCTGAGAAGTATTATGATCTGGCAGCCAGGCTGAGGCCTAATGAATTTGCTGCACTGACAAAAG
AATTAAATGCCTGCAGGGAACAACTTCTAGAAAAGGAAGAAGAAATCTCTGAACTTAAAGCTGAAAGAAACAACACAAGACTATTACTGG
AGCATTTGGAGTGCCTTGTGTCACGACATGAAAGATCACTAAGAATGACGGTGGTAAAACGGCAAGCCCAGTCTCCCTCAGGAGTATCCA
GTGAAGTTGAAGTTCTCAAGGCACTGAAATCTTTGTTTGAGCACCACAAGGCCTTGGATGAAAAGGTAAGGGAGCGACTGAGGGTTTCTT
TAGAAAGAGTCTCTGCACTGGAAGAAGAACTAGCTGCTGCTAATCAGGAGATTGTTGCCTTGCGTGAACAAAATGTTCATATACAAAGAA
AAATGGCATCAAGCGAGGGATCCACAGAGTCAGAACATCTTGAAGGGATGGAACCTGGACAGAAAGTCCATGAGAAGCGTTTGTCCAATG
GTTCTATAGACTCAACCGATGAAACTAGTCAAATAGTTGAACTACAAGAATTGCTTGAAAAGCAAAACTATGAAATGGCCCAGATGAAAG
AACGTTTAGCAGCCCTTTCTTCCCGAGTGGGAGAGGTGGAACAGGAAGCAGAGACAGCAAGAAAGGATCTCATTAAAACAGAAGAAATGA
ACACCAAGTATCAAAGGGACATTAGGGAGGCCATGGCACAAAAGGAAGATATGGAAGAAAGAATTACAACCCTTGAAAAGCGTTACCTCA
GTGCTCAGAGAGAATCTACCTCCATACATGACATGAATGATAAACTAGAAAATGAGTTAGCAAATAAAGAAGCTATCCTGCGGCAGATGG
AAGAGAAAAACAGACAGTTACAAGAACGTCTTGAGCTAGCTGAACAAAAGTTGCAGCAGACCATGAGAAAGGCTGAAACCTTGCCTGAAG
TAGAGGCTGAACTGGCTCAGAGAATTGCAGCCCTAACCAAGGCTGAAGAGAGACATGGAAATATTGAAGAACGTATGAGACATTTAGAGG
GTCAACTTGAAGAGAAGAATCAAGAACTTCAAAGAGCTAGGCAAAGAGAGAAAATGAATGAGGAGCATAACAAGAGATTATCGGATACGG
TTGATAGACTTCTGACTGAATCCAATGAACGCCTACAACTACACTTAAAGGAAAGAATGGCTGCTCTAGAAGAAAAGAATGTTTTAATTC
AAGAATCAGAAACTTTCAGAAAGAATCTTGAAGAATCTTTACATGATAAGGAAAGATTAGCAGAAGAAATTGAAAAGCTGAGATCTGAAC
TTGACCAATTGAAAATGAGAACTGGCTCTTTAATTGAACCCACAATACCAAGAACTCATCTAGACACCTCAGCTGAGTTGCGGTACTCAG
TGGGATCCCTAGTGGACAGCCAGTCTGATTACAGAACAACTAAAGTAATAAGAAGACCAAGGAGAGGCCGCATGGGTGTGCGAAGAGATG
AGCCAAAGGTGAAATCTCTTGGGGATCACGAGTGGAATAGAACTCAACAGATTGGAGTACTAAGCAGCCACCCTTTTGAAAGTGACACTG
AAATGTCTGATATTGATGATGATGACAGAGAAACAATTTTTAGCTCAATGGATCTTCTCTCTCCAAGTGGTCATTCCGATGCCCAGACGC
TAGCCATGATGCTTCAGGAACAATTGGATGCCATCAACAAAGAAATCAGGCTAATTCAGGAAGAAAAAGAATCTACAGAGTTGCGTGCTG
AAGAAATTGAAAATAGAGTGGCTAGTGTGAGCCTCGAAGGCCTGAATTTGGCAAGGGTCCACCCAGGTACCTCCATTACTGCCTCTGTTA
CAGCTTCATCGCTGGCCAGTTCATCTCCCCCCAGTGGACACTCAACTCCAAAGCTCACCCCTCGAAGCCCTGCCAGGGAAATGGATCGGA
TGGGAGTCATGACACTGCCAAGTGATCTGAGGAAACATCGGAGAAAGATTGCAGTTGTGGAAGAAGATGGTCGAGAGGACAAAGCAACAA
TTAAATGTGAAACTTCTCCTCCTCCTACCCCTAGAGCCCTCAGAATGACTCACACTCTCCCTTCTTCCTACCACAATGATGCTCGAAGTA
GTTTATCTGTCTCTCTTGAGCCAGAAAGCCTCGGGCTTGGTAGTGCCAACAGCAGCCAAGACTCTCTTCACAAAGCCCCCAAGAAGAAAG
GAATCAAGTCTTCAATAGGACGTTTGTTTGGTAAAAAAGAAAAAGCTCGACTTGGGCAGCTCCGAGGCTTTATGGAGACTGAAGCTGCAG
CTCAGGAGTCCCTGGGGTTAGGCAAACTCGGAACTCAAGCTGAGAAGGATCGAAGACTAAAGAAAAACACATCTGGGCATGAACTTCTTG
AAGAAGCTCGGAGAAAGGGATTACCTTTTGCCCAGTGGGATGGGCCAACTGTGGTCGCATGGCTAGAGCTTTGGTTGGGAATGCCTGCGT
GGTACGTGGCAGCCTGCCGAGCCAACGTGAAGAGTGGTGCCATCATGTCTGCTTTATCTGACACTGAGATCCAGAGAGAAATTGGAATCA
GCAATCCACTGCATCGCTTAAAACTTCGATTAGCAATCCAGGAGATGGTTTCCCTAACAAGTCCTTCAGCTCCTCCAACATCTCGAACTC
CTTCAGGCAACGTTTGGGTGACTCATGAAGAAATGGAAAATCTTGCAGCTCCAGCAAAAACGAAAGAATCTGAGGAAGGAAGCTGGGCCC
AGTGTCCGGTTTTTCTACAGACCCTGGCTTATGGAGATATGAATCATGAGTGGATTGGAAATGAATGGCTTCCCAGCTTGGGGTTACCTC
AGTACAGAAGTTACTTTATGGAATGCTTGGTAGATGCAAGAATGTTAGATCACCTAACAAAAAAAGATCTCCGTGTCCATTTAAAAATGG
TGGATAGTTTCCATCGAACAAGTTTACAATATGGAATTATGTGCTTAAAGAGGTTGAATTATGACAGAAAAGAACTAGAAAGAAGACGGG
AAGCAAGCCAACATGAAATAAAAGACGTGTTGGTGTGGAGCAATGACCGAGTTATTCGCTGGATACAAGCAATTGGACTTCGAGAATATG
CAAATAATATACTTGAGAGCGGTGTGCATGGCTCACTTATAGCCCTGGATGAAAACTTTGACTACAGCAGCTTAGCTTTATTATTACAGA
TTCCAACACAGAACACCCAGGCAAGGCAGATTCTTGAAAGAGAATACAATAACCTCTTGGCCCTGGGAACTGAAAGGCGACTGGATGAAA
GTGATGACAAGAACTTCAGACGTGGATCAACCTGGAGAAGGCAGTTTCCTCCTCGTGAAGTACATGGAATCAGCATGATGCCTGGGTCCT
CAGAAACATTACCAGCTGGATTTAGGTTAACCACAACCTCTGGGCAGTCAAGAAAAATGACAACAGATGATGGCGTCTTTTCAGTCTACT
CTACCTAAAGTGCACTACCATCTAAGAAGACGAGCAGTGAAAACCTTTGTGAAAACTGAATTCTAAGGAAATAATGACGTCATGACTTAT
TAAAAGCTGAAAAATGTGATTTTTGGGGGGAGTCAGATATTACATTTGATTAGTTTACTACAAATTGTAATAAAATGCTTAAGTCATTTG
AATAATAAACATCATCTACATCATAAACTCTGTACAACAGATGCTTTTATGAAATGAAGCCAGTTGTTTTTCATGTTTTATTGTAATATA
CTAGGCATTTATGTATTACCGTGCATTTCTTTTTAAATGTGTAAGTCTTATGTAAATGGATATAAATATGATTTTTTAAAAAATAAAATA
TATGGTTCATGGAGTCTCGAGTGCAAACATTTGACAATTCCAAGTACTGTTTGTATTTTACCATTCCACCATTTTTACAGTTTTTGGATT
GTTAATAGTCAAATCAATATGTTTCCTTGAAGCATGTTTCATGCTTCAACGTGTTTCTCCTTCAAGTCTGTCAATACTTAAAGCTGAACA
ACCTGCCTCTGATCATGTAAAAAAGAATGATTTAACCTGGAACCGGAGCCAAAAATAGAGCTTTAAAGGCAATCAGGGATGTCCTATATC
TTTAGAAATAGCACTGTGATGGCTTGATCTCCTTTTCAATACAAAACAAAGCCAAGCTGTTTACAAGGGTCAAAAGCAATTATTTAAAAA

>92517_92517_4_TMTC2-PPFIA2_TMTC2_chr12_83455610_ENST00000549919_PPFIA2_chr12_81851645_ENST00000549325_length(amino acids)=1965AA_BP=816
MRSSHFVESLGRPLWLSIILEIFSDSHLTRSFCLYSVSKQQQQKCMEPSSCRKTSSGLRTPTDYTLCRAIKTNQDLLPETPWTHIFYNDF
WGTLLTHSGSHKSYRPLCTLSFRLNHAIGGLNPWSYHLVNVLLHAAVTGLFTSFSKILLGDGYWTFMAGLMFASHPIHTEAVAGIVGRAD
VGASLFFLLSLLCYIKHCSTRGYSARTWGWFLGSGLCAGCSMLWKEQGVTVLAVSAVYDVFVFHRLKIKQILPTIYKRKNLSLFLSISLL
IFWGSSLLGARLYWMGNKPPSFSNSDNPAADSDSLLTRTLTFFYLPTKNLWLLLCPDTLSFDWSMDAVPLLKTVCDWRNLHTVAFYTGLL
LLAYYGLKSPSVDRECNGKTVTNGKQNANGHSCLSDVEYQNSETKSSFASKVENGIKNDVSQRTQLPSTENIVVLSLSLLIIPFVPATNL
FFYVGFVIAERVLYIPSMGFCLLITVGARALYVKVQKRFLKSLIFYATATLIVFYGLKTAIRNGDWQNEEMLYRSGIKVNPAKAWGNLGN
VLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIP
DENLKDPHAHKSSVTSCLYNLGKLYHEQGHYEEALSVYKEAIQKMPRQFAPQSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHL
TYGKLLALTGRKSEAEKLFLKAIELDPTKGNCYMHYGQFLLEEARLIEAAEMAKKAAELDSTEFDVVFNAAHMLRQASLNEAAEKYYDLA
ARLRPNEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHK
ALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQE
LLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLE
NELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQRE
KMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIP
RTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETIFSSM
DLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTP
KLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRALRMTHTLPSSYHNDARSSLSVSLEPESLGLGSAN
SSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKNTSGHELLEEARRKGLPFAQWDGPT
VVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAA
PAKTKESEEGSWAQCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLK
RLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYN

--------------------------------------------------------------
>92517_92517_5_TMTC2-PPFIA2_TMTC2_chr12_83455610_ENST00000549919_PPFIA2_chr12_81851645_ENST00000549396_length(transcript)=9017nt_BP=4118nt
TCTAGAGTTATCAATCTGAATTATAAATTTTGTAAAATTATTCACAAAAGCACTTATTTTGTAAGTGTAGTGTAGAATGTTAGATGTATG
ACCTATAATTAATTCCATTAATCCTCAAATAAAACTGTGGAATCATTTTCCTTTCAAACAGCAGTTTAAATTCAAACTGTATTACCATTA
GCATAAGAATAGCTTTTAACAATAATTAAAATCCTAATGGTATCATGAAATAATTTTAGTTTAGTTATCCTTTTGATGTAAATATTTATC
CAGTGGGAGAACCTGATTTGTTAAACATTTTATATGAATTTGATTTGAGAAATGCACAGCACCATATAAATATATCACTGTAGGAGGCAG
TGTAGCCATAAGGAAAACATACCGGATTGAGTGTCAAGAACTGGTGTCTGTATGGTGCTGTACTGCACAAGCTTCATATGACCTTAATTT
CCGAGCATCAGTTTCATCATTGGTTAAAAAAAAAGAGATGACAGTATCAGACTTGCCTCACGGCTGTCTGCCAATTAAGTGAATTAGAAA
ATTATTTTCAATTATATAGTGCTGGGCAAGGTGAATGATTGCTATTACTGTTGTCATCACTGTTGTTTGAAGCACTGTGCTTTGGGAAGC
AAATCTGGTTCACATCTTTTGAACATTTAAATGAAGAGAATGTGTCTCAGTGCTCTAGTGTGTATTAAAACAGCCTTTTAACAAGAATGT
TTTGAACCCTGCCCAATACCTGCACATGCTTTTGTTAATACTTCATTACATAAAATGACCAAGAAGCTGTCATAAGAATTTAAAGGAACA
TTTACCCTCATCTTTAAAATGTATCTTAAAAGAGAGATAAGATTCTAATTACAAATTTTGAACAGTTTATTTTCTCTCTATGAAAAATTT
CCAAGAATGATACAAAAGCACTTTTATGTGAAGAGGATACACTGGAACATTGAGGTCTTGATCTCATTTTAGTAACTCTCTGATGTGATT
AATTCATAAGCACTGAGTTGTAGCTCATTCCTTCTGGCAAAATTCCAGCACTTGATTGTTACCTTATAAACTTTTAATAAGAGTAATTTT
AAAAACTGCACTTGACTCTTGCTTTATGAAAAGCTGGAAATGTAAAAAGTTAAAAATGCTTGACAATTTTTCTGAGCTCTAGTCAGAAAC
AGTGGCTATGCCCTTTTATAGATGACAGCCCAAAGGCGAGTTTGTAAAACGATAAATAAATTGTAAAGATCTATCGAGTGGCAACTTGGA
TGGTTTAATGCCTATGGGTTAGAAACCCAGGAGTTAATGTTTAAAGTGATTTGGATAAATGTGAACATGTTTAAATCTTTAGTATTATTC
CTTTAAGCCAAATGTGAACGATAGTTATTTTGACAAAGTTTGGGTTACCTCGATAGCCTGATTTTTACAGAAGTACCGTGTATCTCAAAT
TGTTAACTGATGAATGGGTGGTGCTGCTGGATTATTTCCTGTGTTTTGTGTTTTTCTTAGTTTTAATTTCTTTGTTATTCAAGTTATACT
ATCACCTCGTCCAAAGTTGGGTCTCAGGATTAGATTAATAAACTAACCAAGTAAATTTGGGAAGTATGACTAACTTACATAAAGAAAATA
ATTGGGGTTATTTTTTTGTATTATTATTTTAAAATATGTAATCAGCACTTTTGAGAAGCTCTCATTTTGTTGAATCTCTAGGCAGACCTT
TGTGGTTAAGCATCATCCTGGAAATTTTTTCTGACAGTCATTTGACCAGGTCTTTCTGTTTATACTCAGTGTCAAAACAACAACAACAAA
AATGCATGGAACCATCTAGTTGCAGGAAAACAAGCTCAGGACTCAGGACTCCCACTGATTATACATTATGCCGTGCTATCAAGACTAATC
AGGACCTTCTCCCAGAAACTCCATGGACGCACATTTTCTACAATGATTTTTGGGGGACTCTTCTAACCCACAGTGGCAGCCACAAGTCCT
ACCGGCCACTCTGCACTCTTTCTTTTCGCCTGAACCATGCCATTGGAGGGTTGAATCCCTGGAGCTACCATCTTGTCAATGTCCTGTTGC
ATGCAGCAGTCACTGGTCTCTTCACAAGCTTCTCCAAGATCCTCCTTGGTGATGGATACTGGACATTCATGGCTGGCTTGATGTTTGCTT
CTCACCCCATTCACACGGAGGCAGTGGCAGGAATCGTGGGACGAGCCGATGTCGGGGCCAGTCTCTTCTTTCTCCTCTCCTTGCTCTGCT
ACATTAAACACTGTTCTACAAGAGGCTACTCAGCCAGAACCTGGGGCTGGTTCCTGGGGTCAGGACTGTGCGCAGGATGCAGCATGTTGT
GGAAGGAACAAGGAGTGACTGTTCTCGCAGTTTCAGCAGTTTATGATGTCTTTGTCTTTCACAGGCTGAAAATAAAACAGATATTACCTA
CCATTTACAAAAGGAAGAACTTGTCGCTTTTCCTAAGCATTAGTTTGTTAATTTTCTGGGGTTCCTCCCTTTTGGGTGCCCGGTTATACT
GGATGGGAAACAAACCACCAAGCTTTTCCAACTCGGACAACCCCGCTGCTGATTCGGACAGCCTCCTCACCCGCACTCTCACCTTCTTCT
ACTTGCCAACCAAGAACCTCTGGCTGTTGCTATGTCCAGATACCCTCAGTTTTGATTGGTCAATGGATGCTGTGCCTCTGCTCAAAACAG
TTTGTGACTGGAGAAACCTACACACTGTGGCCTTCTATACTGGACTCCTTCTCCTTGCCTACTATGGTTTGAAGAGCCCGAGCGTAGACA
GAGAATGCAATGGGAAAACTGTAACAAATGGCAAGCAGAATGCAAATGGACATAGCTGCCTTTCAGATGTGGAGTACCAGAACTCAGAGA
CTAAGTCCAGCTTTGCATCCAAAGTAGAAAATGGCATTAAAAACGATGTATCACAGAGAACCCAGCTTCCTTCTACGGAGAACATTGTTG
TTCTGTCTTTATCTTTGTTAATCATACCCTTTGTTCCTGCCACGAACCTGTTTTTCTATGTCGGCTTTGTAATTGCAGAGCGAGTATTAT
ATATTCCTAGTATGGGCTTCTGCCTACTGATTACAGTGGGTGCTAGAGCCCTTTATGTCAAAGTCCAAAAGCGGTTCCTCAAGAGCTTGA
TTTTTTATGCTACAGCTACACTAATTGTTTTTTATGGACTCAAGACTGCGATCAGGAATGGAGACTGGCAGAATGAGGAAATGCTTTATA
GATCAGGGATAAAAGTAAACCCAGCTAAAGCATGGGGTAACCTTGGAAATGTTCTGAAGAGTCAGAGCAAAATTTCTGAAGCTGAAAGCG
CCTATAGAAATGCTTTGTACTACCGCAGCAACATGGCTGACATGCTTTATAATTTAGGGCTACTTCTCCAGGAGAACAGCAGGTTTGCAG
AAGCACTACATTATTATAAATTGGCCATTGGGAGCAGGCCTACCCTGGCTTCTGCATATTTAAATACCGGTATTATTCTAATGAACCAAG
GAAGGACGGAAGAAGCCCGACGGACATTCTTAAAGTGTTCGGAGATCCCAGATGAAAACCTAAAGGACCCTCATGCACACAAGAGCTCTG
TTACCAGTTGTTTGTACAACCTAGGAAAGCTGTATCATGAGCAGGGACACTATGAGGAAGCCCTTAGTGTATACAAGGAAGCAATTCAGA
AAATGCCAAGGCAGTTTGCCCCACAGAGCTTGTACAACATGATGGGTGAAGCATATATGCGTTTAAGCAAACTCCCCGAAGCAGAGCATT
GGTATATGGAATCACTGAGATCCAAGACTGACCACATCCCTGCTCATCTCACCTATGGGAAGCTGCTAGCTCTAACAGGTCGTAAGAGTG
AGGCTGAAAAGCTCTTCTTGAAGGCTATTGAGCTGGATCCCACCAAAGGAAACTGTTACATGCATTATGGTCAGTTTCTTCTGGAAGAAG
CTCGTCTCATAGAAGCAGCTGAGATGGCAAAAAAAGCAGCTGAACTAGACAGCACAGAGTTTGATGTTGTCTTCAATGCTGCCCACATGC
TCAGACAGGCTAGCCTCAATGAAGCAGCTGAGAAGTATTATGATCTGGCAGCCAGGCTGAGGCCTAATGAATTTGCTGCACTGACAAAAG
AATTAAATGCCTGCAGGGAACAACTTCTAGAAAAGGAAGAAGAAATCTCTGAACTTAAAGCTGAAAGAAACAACACAAGACTATTACTGG
AGCATTTGGAGTGCCTTGTGTCACGACATGAAAGATCACTAAGAATGACGGTGGTAAAACGGCAAGCCCAGTCTCCCTCAGGAGTATCCA
GTGAAGTTGAAGTTCTCAAGGCACTGAAATCTTTGTTTGAGCACCACAAGGCCTTGGATGAAAAGGTAAGGGAGCGACTGAGGGTTTCTT
TAGAAAGAGTCTCTGCACTGGAAGAAGAACTAGCTGCTGCTAATCAGGAGATTGTTGCCTTGCGTGAACAAAATGTTCATATACAAAGAA
AAATGGCATCAAGCGAGGGATCCACAGAGTCAGAACATCTTGAAGGGATGGAACCTGGACAGAAAGTCCATGAGAAGCGTTTGTCCAATG
GTTCTATAGACTCAACCGATGAAACTAGTCAAATAGTTGAACTACAAGAATTGCTTGAAAAGCAAAACTATGAAATGGCCCAGATGAAAG
AACGTTTAGCAGCCCTTTCTTCCCGAGTGGGAGAGGTGGAACAGGAAGCAGAGACAGCAAGAAAGGATCTCATTAAAACAGAAGAAATGA
ACACCAAGTATCAAAGGGACATTAGGGAGGCCATGGCACAAAAGGAAGATATGGAAGAAAGAATTACAACCCTTGAAAAGCGTTACCTCA
GTGCTCAGAGAGAATCTACCTCCATACATGACATGAATGATAAACTAGAAAATGAGTTAGCAAATAAAGAAGCTATCCTGCGGCAGATGG
AAGAGAAAAACAGACAGTTACAAGAACGTCTTGAGCTAGCTGAACAAAAGTTGCAGCAGACCATGAGAAAGGCTGAAACCTTGCCTGAAG
TAGAGGCTGAACTGGCTCAGAGAATTGCAGCCCTAACCAAGGCTGAAGAGAGACATGGAAATATTGAAGAACGTATGAGACATTTAGAGG
GTCAACTTGAAGAGAAGAATCAAGAACTTCAAAGAGCTAGGCAAAGAGAGAAAATGAATGAGGAGCATAACAAGAGATTATCGGATACGG
TTGATAGACTTCTGACTGAATCCAATGAACGCCTACAACTACACTTAAAGGAAAGAATGGCTGCTCTAGAAGAAAAGAATGTTTTAATTC
AAGAATCAGAAACTTTCAGAAAGAATCTTGAAGAATCTTTACATGATAAGGAAAGATTAGCAGAAGAAATTGAAAAGCTGAGATCTGAAC
TTGACCAATTGAAAATGAGAACTGGCTCTTTAATTGAACCCACAATACCAAGAACTCATCTAGACACCTCAGCTGAGTTGCGGTACTCAG
TGGGATCCCTAGTGGACAGCCAGTCTGATTACAGAACAACTAAAGTAATAAGAAGACCAAGGAGAGGCCGCATGGGTGTGCGAAGAGATG
AGCCAAAGGTGAAATCTCTTGGGGATCACGAGTGGAATAGAACTCAACAGATTGGAGTACTAAGCAGCCACCCTTTTGAAAGTGACACTG
AAATGTCTGATATTGATGATGATGACAGAGAAACAATTTTTAGCTCAATGGATCTTCTCTCTCCAAGTGGTCATTCCGATGCCCAGACGC
TAGCCATGATGCTTCAGGAACAATTGGATGCCATCAACAAAGAAATCAGGCTAATTCAGGAAGAAAAAGAATCTACAGAGTTGCGTGCTG
AAGAAATTGAAAATAGAGTGGCTAGTGTGAGCCTCGAAGGCCTGAATTTGGCAAGGGTCCACCCAGGTACCTCCATTACTGCCTCTGTTA
CAGCTTCATCGCTGGCCAGTTCATCTCCCCCCAGTGGACACTCAACTCCAAAGCTCACCCCTCGAAGCCCTGCCAGGGAAATGGATCGGA
TGGGAGTCATGACACTGCCAAGTGATCTGAGGAAACATCGGAGAAAGATTGCAGTTGTGGAAGAAGATGGTCGAGAGGACAAAGCAACAA
TTAAATGTGAAACTTCTCCTCCTCCTACCCCTAGAGCCCTCAGAATGACTCACACTCTCCCTTCTTCCTACCACAATGATGCTCGAAGTA
GTTTATCTGTCTCTCTTGAGCCAGAAAGCCTCGGGCTTGGTAGTGCCAACAGCAGCCAAGACTCTCTTCACAAAGCCCCCAAGAAGAAAG
GAATCAAGTCTTCAATAGGACGTTTGTTTGGTAAAAAAGAAAAAGCTCGACTTGGGCAGCTCCGAGGCTTTATGGAGACTGAAGCTGCAG
CTCAGGAGTCCCTGGGGTTAGGCAAACTCGGAACTCAAGCTGAGAAGGATCGAAGACTAAAGAAAAAGCATGAACTTCTTGAAGAAGCTC
GGAGAAAGGGATTACCTTTTGCCCAGTGGGATGGGCCAACTGTGGTCGCATGGCTAGAGCTTTGGTTGGGAATGCCTGCGTGGTACGTGG
CAGCCTGCCGAGCCAACGTGAAGAGTGGTGCCATCATGTCTGCTTTATCTGACACTGAGATCCAGAGAGAAATTGGAATCAGCAATCCAC
TGCATCGCTTAAAACTTCGATTAGCAATCCAGGAGATGGTTTCCCTAACAAGTCCTTCAGCTCCTCCAACATCTCGAACTCCTTCAGGCA
ACGTTTGGGTGACTCATGAAGAAATGGAAAATCTTGCAGCTCCAGCAAAAACGAAAGAATCTGAGGAAGGAAGCTGGGCCCAGTGTCCGG
TTTTTCTACAGACCCTGGCTTATGGAGATATGAATCATGAGTGGATTGGAAATGAATGGCTTCCCAGCTTGGGGTTACCTCAGTACAGAA
GTTACTTTATGGAATGCTTGGTAGATGCAAGAATGTTAGATCACCTAACAAAAAAAGATCTCCGTGTCCATTTAAAAATGGTGGATAGTT
TCCATCGAACAAGTTTACAATATGGAATTATGTGCTTAAAGAGGTTGAATTATGACAGAAAAGAACTAGAAAGAAGACGGGAAGCAAGCC
AACATGAAATAAAAGACGTGTTGGTGTGGAGCAATGACCGAGTTATTCGCTGGATACAAGCAATTGGACTTCGAGAATATGCAAATAATA
TACTTGAGAGCGGTGTGCATGGCTCACTTATAGCCCTGGATGAAAACTTTGACTACAGCAGCTTAGCTTTATTATTACAGATTCCAACAC
AGAACACCCAGGCAAGGCAGATTCTTGAAAGAGAATACAATAACCTCTTGGCCCTGGGAACTGAAAGGCGACTGGATGAAAGTGATGACA
AGAACTTCAGACGTGGATCAACCTGGAGAAGGCAGTTTCCTCCTCGTGAAGTACATGGAATCAGCATGATGCCTGGGTCCTCAGAAACAT
TACCAGCTGGATTTAGGTTAACCACAACCTCTGGGCAGTCAAGAAAAATGACAACAGATGTTGCTTCATCAAGACTGCAGAGGTTAGACA
ACTCCACTGTTCGCACATACTCATGTTGACCAGCCACTCAAAGGAGGCAGCACTGACCTGCTATGGCGTCTTTTCAGTCTACTCTACCTA
AAGTGCACTACCATCTAAGAAGACGAGCAGTGAAAACCTTTGTGAAAACTGAATTCTAAGGAAATAATGACGTCATGACTTATTAAAAGC
TGAAAAATGTGATTTTTGGGGGGAGTCAGATATTACATTTGATTAGTTTACTACAAATTGTAATAAAATGCTTAAGTCATTTGAATAATA
AACATCATCTACATCATAAACTCTGTACAACAGATGCTTTTATGAAATGAAGCCAGTTGTTTTTCATGTTTTATTGTAATATACTAGGCA
TTTATGTATTACCGTGCATTTCTTTTTAAATGTGTAAGTCTTATGTAAATGGATATAAATATGATTTTTTAAAAAATAAAATATATGGTT
CATGGAGTCTCGAGTGCAAACATTTGACAATTCCAAGTACTGTTTGTATTTTACCATTCCACCATTTTTACAGTTTTTGGATTGTTAATA
GTCAAATCAATATGTTTCCTTGAAGCATGTTTCATGCTTCAACGTGTTTCTCCTTCAAGTCTGTCAATACTTAAAGCTGAACAACCTGCC
TCTGATCATGTAAAAAAGAATGATTTAACCTGGAACCGGAGCCAAAAATAGAGCTTTAAAGGCAATCAGGGATGTCCTATATCTTTAGAA
ATAGCACTGTGATGGCTTGATCTCCTTTTCAATACAAAACAAAGCCAAGCTGTTTACAAGGGTCAAAAGCAATTATTTAAAAATTTATAT
TAAAAAACCATAATCTTCTCTTGTTACCTGTGGACCAAGAAAAAAAAAAAGATAAAAAAACTTCTTTACTAAGAACCACATGTTCATTCA
AATATCTTGAAATGCCAGCCAGTACTGGACAGTGAATGTCAACCACCGCAGAGTCTGAGGCTCATTTCCACTAGAGAAAACGAAACCCAA
GATACCTTTCCCTTTTGTCAATGTAACAGGGCATTAGCCAGACTCATGTCTAATGTTATAAGCTTTTAGCCGAGATGGCCTTGTTGCGAC
TTCCCTGAAGTCAGTTTTATCAGAGGAAATAAATGAAAGACAGAATGATTAACATATATAGTGTATAAAAGTATAGAAGAGTAATCTCTT
CCCTGTGGCTTTATTTGGTGGTGTTACTGTTGTTTATTCTTTGTTTATATGGGAGATTCAAAGTAAAGCCTATTTAATAATACCATTTAT
CTAACTGCTGATTTTCTGCTGCTTGATCTTATTAAGCGCAAGACCTGTCATTAGTAATTTCTTTTCTGTATTTTAATTTGCTATGTTTGC
ACGTACATTACATTTGTTTTGATGTCTATTTTTATTTAACAGATTCAGTCAAAAGGTAATGATAACAGAAACCCTTTCCATTGTCAATAA

>92517_92517_5_TMTC2-PPFIA2_TMTC2_chr12_83455610_ENST00000549919_PPFIA2_chr12_81851645_ENST00000549396_length(amino acids)=1972AA_BP=816
MRSSHFVESLGRPLWLSIILEIFSDSHLTRSFCLYSVSKQQQQKCMEPSSCRKTSSGLRTPTDYTLCRAIKTNQDLLPETPWTHIFYNDF
WGTLLTHSGSHKSYRPLCTLSFRLNHAIGGLNPWSYHLVNVLLHAAVTGLFTSFSKILLGDGYWTFMAGLMFASHPIHTEAVAGIVGRAD
VGASLFFLLSLLCYIKHCSTRGYSARTWGWFLGSGLCAGCSMLWKEQGVTVLAVSAVYDVFVFHRLKIKQILPTIYKRKNLSLFLSISLL
IFWGSSLLGARLYWMGNKPPSFSNSDNPAADSDSLLTRTLTFFYLPTKNLWLLLCPDTLSFDWSMDAVPLLKTVCDWRNLHTVAFYTGLL
LLAYYGLKSPSVDRECNGKTVTNGKQNANGHSCLSDVEYQNSETKSSFASKVENGIKNDVSQRTQLPSTENIVVLSLSLLIIPFVPATNL
FFYVGFVIAERVLYIPSMGFCLLITVGARALYVKVQKRFLKSLIFYATATLIVFYGLKTAIRNGDWQNEEMLYRSGIKVNPAKAWGNLGN
VLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIP
DENLKDPHAHKSSVTSCLYNLGKLYHEQGHYEEALSVYKEAIQKMPRQFAPQSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHL
TYGKLLALTGRKSEAEKLFLKAIELDPTKGNCYMHYGQFLLEEARLIEAAEMAKKAAELDSTEFDVVFNAAHMLRQASLNEAAEKYYDLA
ARLRPNEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHK
ALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQE
LLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLE
NELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQRE
KMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIP
RTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETIFSSM
DLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTP
KLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRALRMTHTLPSSYHNDARSSLSVSLEPESLGLGSAN
SSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVA
WLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAK
TKESEEGSWAQCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLN
YDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLL

--------------------------------------------------------------
>92517_92517_6_TMTC2-PPFIA2_TMTC2_chr12_83455610_ENST00000549919_PPFIA2_chr12_81851645_ENST00000550584_length(transcript)=8924nt_BP=4118nt
TCTAGAGTTATCAATCTGAATTATAAATTTTGTAAAATTATTCACAAAAGCACTTATTTTGTAAGTGTAGTGTAGAATGTTAGATGTATG
ACCTATAATTAATTCCATTAATCCTCAAATAAAACTGTGGAATCATTTTCCTTTCAAACAGCAGTTTAAATTCAAACTGTATTACCATTA
GCATAAGAATAGCTTTTAACAATAATTAAAATCCTAATGGTATCATGAAATAATTTTAGTTTAGTTATCCTTTTGATGTAAATATTTATC
CAGTGGGAGAACCTGATTTGTTAAACATTTTATATGAATTTGATTTGAGAAATGCACAGCACCATATAAATATATCACTGTAGGAGGCAG
TGTAGCCATAAGGAAAACATACCGGATTGAGTGTCAAGAACTGGTGTCTGTATGGTGCTGTACTGCACAAGCTTCATATGACCTTAATTT
CCGAGCATCAGTTTCATCATTGGTTAAAAAAAAAGAGATGACAGTATCAGACTTGCCTCACGGCTGTCTGCCAATTAAGTGAATTAGAAA
ATTATTTTCAATTATATAGTGCTGGGCAAGGTGAATGATTGCTATTACTGTTGTCATCACTGTTGTTTGAAGCACTGTGCTTTGGGAAGC
AAATCTGGTTCACATCTTTTGAACATTTAAATGAAGAGAATGTGTCTCAGTGCTCTAGTGTGTATTAAAACAGCCTTTTAACAAGAATGT
TTTGAACCCTGCCCAATACCTGCACATGCTTTTGTTAATACTTCATTACATAAAATGACCAAGAAGCTGTCATAAGAATTTAAAGGAACA
TTTACCCTCATCTTTAAAATGTATCTTAAAAGAGAGATAAGATTCTAATTACAAATTTTGAACAGTTTATTTTCTCTCTATGAAAAATTT
CCAAGAATGATACAAAAGCACTTTTATGTGAAGAGGATACACTGGAACATTGAGGTCTTGATCTCATTTTAGTAACTCTCTGATGTGATT
AATTCATAAGCACTGAGTTGTAGCTCATTCCTTCTGGCAAAATTCCAGCACTTGATTGTTACCTTATAAACTTTTAATAAGAGTAATTTT
AAAAACTGCACTTGACTCTTGCTTTATGAAAAGCTGGAAATGTAAAAAGTTAAAAATGCTTGACAATTTTTCTGAGCTCTAGTCAGAAAC
AGTGGCTATGCCCTTTTATAGATGACAGCCCAAAGGCGAGTTTGTAAAACGATAAATAAATTGTAAAGATCTATCGAGTGGCAACTTGGA
TGGTTTAATGCCTATGGGTTAGAAACCCAGGAGTTAATGTTTAAAGTGATTTGGATAAATGTGAACATGTTTAAATCTTTAGTATTATTC
CTTTAAGCCAAATGTGAACGATAGTTATTTTGACAAAGTTTGGGTTACCTCGATAGCCTGATTTTTACAGAAGTACCGTGTATCTCAAAT
TGTTAACTGATGAATGGGTGGTGCTGCTGGATTATTTCCTGTGTTTTGTGTTTTTCTTAGTTTTAATTTCTTTGTTATTCAAGTTATACT
ATCACCTCGTCCAAAGTTGGGTCTCAGGATTAGATTAATAAACTAACCAAGTAAATTTGGGAAGTATGACTAACTTACATAAAGAAAATA
ATTGGGGTTATTTTTTTGTATTATTATTTTAAAATATGTAATCAGCACTTTTGAGAAGCTCTCATTTTGTTGAATCTCTAGGCAGACCTT
TGTGGTTAAGCATCATCCTGGAAATTTTTTCTGACAGTCATTTGACCAGGTCTTTCTGTTTATACTCAGTGTCAAAACAACAACAACAAA
AATGCATGGAACCATCTAGTTGCAGGAAAACAAGCTCAGGACTCAGGACTCCCACTGATTATACATTATGCCGTGCTATCAAGACTAATC
AGGACCTTCTCCCAGAAACTCCATGGACGCACATTTTCTACAATGATTTTTGGGGGACTCTTCTAACCCACAGTGGCAGCCACAAGTCCT
ACCGGCCACTCTGCACTCTTTCTTTTCGCCTGAACCATGCCATTGGAGGGTTGAATCCCTGGAGCTACCATCTTGTCAATGTCCTGTTGC
ATGCAGCAGTCACTGGTCTCTTCACAAGCTTCTCCAAGATCCTCCTTGGTGATGGATACTGGACATTCATGGCTGGCTTGATGTTTGCTT
CTCACCCCATTCACACGGAGGCAGTGGCAGGAATCGTGGGACGAGCCGATGTCGGGGCCAGTCTCTTCTTTCTCCTCTCCTTGCTCTGCT
ACATTAAACACTGTTCTACAAGAGGCTACTCAGCCAGAACCTGGGGCTGGTTCCTGGGGTCAGGACTGTGCGCAGGATGCAGCATGTTGT
GGAAGGAACAAGGAGTGACTGTTCTCGCAGTTTCAGCAGTTTATGATGTCTTTGTCTTTCACAGGCTGAAAATAAAACAGATATTACCTA
CCATTTACAAAAGGAAGAACTTGTCGCTTTTCCTAAGCATTAGTTTGTTAATTTTCTGGGGTTCCTCCCTTTTGGGTGCCCGGTTATACT
GGATGGGAAACAAACCACCAAGCTTTTCCAACTCGGACAACCCCGCTGCTGATTCGGACAGCCTCCTCACCCGCACTCTCACCTTCTTCT
ACTTGCCAACCAAGAACCTCTGGCTGTTGCTATGTCCAGATACCCTCAGTTTTGATTGGTCAATGGATGCTGTGCCTCTGCTCAAAACAG
TTTGTGACTGGAGAAACCTACACACTGTGGCCTTCTATACTGGACTCCTTCTCCTTGCCTACTATGGTTTGAAGAGCCCGAGCGTAGACA
GAGAATGCAATGGGAAAACTGTAACAAATGGCAAGCAGAATGCAAATGGACATAGCTGCCTTTCAGATGTGGAGTACCAGAACTCAGAGA
CTAAGTCCAGCTTTGCATCCAAAGTAGAAAATGGCATTAAAAACGATGTATCACAGAGAACCCAGCTTCCTTCTACGGAGAACATTGTTG
TTCTGTCTTTATCTTTGTTAATCATACCCTTTGTTCCTGCCACGAACCTGTTTTTCTATGTCGGCTTTGTAATTGCAGAGCGAGTATTAT
ATATTCCTAGTATGGGCTTCTGCCTACTGATTACAGTGGGTGCTAGAGCCCTTTATGTCAAAGTCCAAAAGCGGTTCCTCAAGAGCTTGA
TTTTTTATGCTACAGCTACACTAATTGTTTTTTATGGACTCAAGACTGCGATCAGGAATGGAGACTGGCAGAATGAGGAAATGCTTTATA
GATCAGGGATAAAAGTAAACCCAGCTAAAGCATGGGGTAACCTTGGAAATGTTCTGAAGAGTCAGAGCAAAATTTCTGAAGCTGAAAGCG
CCTATAGAAATGCTTTGTACTACCGCAGCAACATGGCTGACATGCTTTATAATTTAGGGCTACTTCTCCAGGAGAACAGCAGGTTTGCAG
AAGCACTACATTATTATAAATTGGCCATTGGGAGCAGGCCTACCCTGGCTTCTGCATATTTAAATACCGGTATTATTCTAATGAACCAAG
GAAGGACGGAAGAAGCCCGACGGACATTCTTAAAGTGTTCGGAGATCCCAGATGAAAACCTAAAGGACCCTCATGCACACAAGAGCTCTG
TTACCAGTTGTTTGTACAACCTAGGAAAGCTGTATCATGAGCAGGGACACTATGAGGAAGCCCTTAGTGTATACAAGGAAGCAATTCAGA
AAATGCCAAGGCAGTTTGCCCCACAGAGCTTGTACAACATGATGGGTGAAGCATATATGCGTTTAAGCAAACTCCCCGAAGCAGAGCATT
GGTATATGGAATCACTGAGATCCAAGACTGACCACATCCCTGCTCATCTCACCTATGGGAAGCTGCTAGCTCTAACAGGTCGTAAGAGTG
AGGCTGAAAAGCTCTTCTTGAAGGCTATTGAGCTGGATCCCACCAAAGGAAACTGTTACATGCATTATGGTCAGTTTCTTCTGGAAGAAG
CTCGTCTCATAGAAGCAGCTGAGATGGCAAAAAAAGCAGCTGAACTAGACAGCACAGAGTTTGATGTTGTCTTCAATGCTGCCCACATGC
TCAGACAGGCTAGCCTCAATGAAGCAGCTGAGAAGTATTATGATCTGGCAGCCAGGCTGAGGCCTAATGAATTTGCTGCACTGACAAAAG
AATTAAATGCCTGCAGGGAACAACTTCTAGAAAAGGAAGAAGAAATCTCTGAACTTAAAGCTGAAAGAAACAACACAAGACTATTACTGG
AGCATTTGGAGTGCCTTGTGTCACGACATGAAAGATCACTAAGAATGACGGTGGTAAAACGGCAAGCCCAGTCTCCCTCAGGAGTATCCA
GTGAAGTTGAAGTTCTCAAGGCACTGAAATCTTTGTTTGAGCACCACAAGGCCTTGGATGAAAAGGTAAGGGAGCGACTGAGGGTTTCTT
TAGAAAGAGTCTCTGCACTGGAAGAAGAACTAGCTGCTGCTAATCAGGAGATTGTTGCCTTGCGTGAACAAAATGTTCATATACAAAGAA
AAATGGCATCAAGCGAGGGATCCACAGAGTCAGAACATCTTGAAGGGATGGAACCTGGACAGAAAGTCCATGAGAAGCGTTTGTCCAATG
GTTCTATAGACTCAACCGATGAAACTAGTCAAATAGTTGAACTACAAGAATTGCTTGAAAAGCAAAACTATGAAATGGCCCAGATGAAAG
AACGTTTAGCAGCCCTTTCTTCCCGAGTGGGAGAGGTGGAACAGGAAGCAGAGACAGCAAGAAAGGATCTCATTAAAACAGAAGAAATGA
ACACCAAGTATCAAAGGGACATTAGGGAGGCCATGGCACAAAAGGAAGATATGGAAGAAAGAATTACAACCCTTGAAAAGCGTTACCTCA
GTGCTCAGAGAGAATCTACCTCCATACATGACATGAATGATAAACTAGAAAATGAGTTAGCAAATAAAGAAGCTATCCTGCGGCAGATGG
AAGAGAAAAACAGACAGTTACAAGAACGTCTTGAGCTAGCTGAACAAAAGTTGCAGCAGACCATGAGAAAGGCTGAAACCTTGCCTGAAG
TAGAGGCTGAACTGGCTCAGAGAATTGCAGCCCTAACCAAGGCTGAAGAGAGACATGGAAATATTGAAGAACGTATGAGACATTTAGAGG
GTCAACTTGAAGAGAAGAATCAAGAACTTCAAAGAGCTAGGCAAAGAGAGAAAATGAATGAGGAGCATAACAAGAGATTATCGGATACGG
TTGATAGACTTCTGACTGAATCCAATGAACGCCTACAACTACACTTAAAGGAAAGAATGGCTGCTCTAGAAGAAAAGAATGTTTTAATTC
AAGAATCAGAAACTTTCAGAAAGAATCTTGAAGAATCTTTACATGATAAGGAAAGATTAGCAGAAGAAATTGAAAAGCTGAGATCTGAAC
TTGACCAATTGAAAATGAGAACTGGCTCTTTAATTGAACCCACAATACCAAGAACTCATCTAGACACCTCAGCTGAGTTGCGGTACTCAG
TGGGATCCCTAGTGGACAGCCAGTCTGATTACAGAACAACTAAAGTAATAAGAAGACCAAGGAGAGGCCGCATGGGTGTGCGAAGAGATG
AGCCAAAGGTGAAATCTCTTGGGGATCACGAGTGGAATAGAACTCAACAGATTGGAGTACTAAGCAGCCACCCTTTTGAAAGTGACACTG
AAATGTCTGATATTGATGATGATGACAGAGAAACAATTTTTAGCTCAATGGATCTTCTCTCTCCAAGTGGTCATTCCGATGCCCAGACGC
TAGCCATGATGCTTCAGGAACAATTGGATGCCATCAACAAAGAAATCAGGCTAATTCAGGAAGAAAAAGAATCTACAGAGTTGCGTGCTG
AAGAAATTGAAAATAGAGTGGCTAGTGTGAGCCTCGAAGGCCTGAATTTGGCAAGGGTCCACCCAGGTACCTCCATTACTGCCTCTGTTA
CAGCTTCATCGCTGGCCAGTTCATCTCCCCCCAGTGGACACTCAACTCCAAAGCTCACCCCTCGAAGCCCTGCCAGGGAAATGGATCGGA
TGGGAGTCATGACACTGCCAAGTGATCTGAGGAAACATCGGAGAAAGATTGCAGTTGTGGAAGAAGATGGTCGAGAGGACAAAGCAACAA
TTAAATGTGAAACTTCTCCTCCTCCTACCCCTAGAGCCCTCAGAATGACTCACACTCTCCCTTCTTCCTACCACAATGATGCTCGAAGTA
GTTTATCTGTCTCTCTTGAGCCAGAAAGCCTCGGGCTTGGTAGTGCCAACAGCAGCCAAGACTCTCTTCACAAAGCCCCCAAGAAGAAAG
GAATCAAGTCTTCAATAGGACGTTTGTTTGGTAAAAAAGAAAAAGCTCGACTTGGGCAGCTCCGAGGCTTTATGGAGACTGAAGCTGCAG
CTCAGGAGTCCCTGGGGTTAGGCAAACTCGGAACTCAAGCTGAGAAGGATCGAAGACTAAAGAAAAAGCATGAACTTCTTGAAGAAGCTC
GGAGAAAGGGATTACCTTTTGCCCAGTGGGATGGGCCAACTGTGGTCGCATGGCTAGAGCTTTGGTTGGGAATGCCTGCGTGGTACGTGG
CAGCCTGCCGAGCCAACGTGAAGAGTGGTGCCATCATGTCTGCTTTATCTGACACTGAGATCCAGAGAGAAATTGGAATCAGCAATCCAC
TGCATCGCTTAAAACTTCGATTAGCAATCCAGGAGATGGTTTCCCTAACAAGTCCTTCAGCTCCTCCAACATCTCGAACTCCTTCAGGCA
ACGTTTGGGTGACTCATGAAGAAATGGAAAATCTTGCAGCTCCAGCAAAAACGAAAGAATCTGAGGAAGGAAGCTGGGCCCAGTGTCCGG
TTTTTCTACAGACCCTGGCTTATGGAGATATGAATCATGAGTGGATTGGAAATGAATGGCTTCCCAGCTTGGGGTTACCTCAGTACAGAA
GTTACTTTATGGAATGCTTGGTAGATGCAAGAATGTTAGATCACCTAACAAAAAAAGATCTCCGTGTCCATTTAAAAATGGTGGATAGTT
TCCATCGAACAAGTTTACAATATGGAATTATGTGCTTAAAGAGGTTGAATTATGACAGAAAAGAACTAGAAAGAAGACGGGAAGCAAGCC
AACATGAAATAAAAGACGTGTTGGTGTGGAGCAATGACCGAGTTATTCGCTGGATACAAGCAATTGGACTTCGAGAATATGCAAATAATA
TACTTGAGAGCGGTGTGCATGGCTCACTTATAGCCCTGGATGAAAACTTTGACTACAGCAGCTTAGCTTTATTATTACAGATTCCAACAC
AGAACACCCAGGCAAGGCAGATTCTTGAAAGAGAATACAATAACCTCTTGGCCCTGGGAACTGAAAGGCGACTGGATGAAAGTGATGACA
AGAACTTCAGACGTGGATCAACCTGGAGAAGGCAGTTTCCTCCTCGTGAAGTACATGGAATCAGCATGATGCCTGGGTCCTCAGAAACAT
TACCAGCTGGATTTAGGTTAACCACAACCTCTGGGCAGTCAAGAAAAATGACAACAGATGATGGCGTCTTTTCAGTCTACTCTACCTAAA
GTGCACTACCATCTAAGAAGACGAGCAGTGAAAACCTTTGTGAAAACTGAATTCTAAGGAAATAATGACGTCATGACTTATTAAAAGCTG
AAAAATGTGATTTTTGGGGGGAGTCAGATATTACATTTGATTAGTTTACTACAAATTGTAATAAAATGCTTAAGTCATTTGAATAATAAA
CATCATCTACATCATAAACTCTGTACAACAGATGCTTTTATGAAATGAAGCCAGTTGTTTTTCATGTTTTATTGTAATATACTAGGCATT
TATGTATTACCGTGCATTTCTTTTTAAATGTGTAAGTCTTATGTAAATGGATATAAATATGATTTTTTAAAAAATAAAATATATGGTTCA
TGGAGTCTCGAGTGCAAACATTTGACAATTCCAAGTACTGTTTGTATTTTACCATTCCACCATTTTTACAGTTTTTGGATTGTTAATAGT
CAAATCAATATGTTTCCTTGAAGCATGTTTCATGCTTCAACGTGTTTCTCCTTCAAGTCTGTCAATACTTAAAGCTGAACAACCTGCCTC
TGATCATGTAAAAAAGAATGATTTAACCTGGAACCGGAGCCAAAAATAGAGCTTTAAAGGCAATCAGGGATGTCCTATATCTTTAGAAAT
AGCACTGTGATGGCTTGATCTCCTTTTCAATACAAAACAAAGCCAAGCTGTTTACAAGGGTCAAAAGCAATTATTTAAAAATTTATATTA
AAAAACCATAATCTTCTCTTGTTACCTGTGGACCAAGAAAAAAAAAAAGATAAAAAAACTTCTTTACTAAGAACCACATGTTCATTCAAA
TATCTTGAAATGCCAGCCAGTACTGGACAGTGAATGTCAACCACCGCAGAGTCTGAGGCTCATTTCCACTAGAGAAAACGAAACCCAAGA
TACCTTTCCCTTTTGTCAATGTAACAGGGCATTAGCCAGACTCATGTCTAATGTTATAAGCTTTTAGCCGAGATGGCCTTGTTGCGACTT
CCCTGAAGTCAGTTTTATCAGAGGAAATAAATGAAAGACAGAATGATTAACATATATAGTGTATAAAAGTATAGAAGAGTAATCTCTTCC
CTGTGGCTTTATTTGGTGGTGTTACTGTTGTTTATTCTTTGTTTATATGGGAGATTCAAAGTAAAGCCTATTTAATAATACCATTTATCT
AACTGCTGATTTTCTGCTGCTTGATCTTATTAAGCGCAAGACCTGTCATTAGTAATTTCTTTTCTGTATTTTAATTTGCTATGTTTGCAC
GTACATTACATTTGTTTTGATGTCTATTTTTATTTAACAGATTCAGTCAAAAGGTAATGATAACAGAAACCCTTTCCATTGTCAATAAAA

>92517_92517_6_TMTC2-PPFIA2_TMTC2_chr12_83455610_ENST00000549919_PPFIA2_chr12_81851645_ENST00000550584_length(amino acids)=1962AA_BP=816
MRSSHFVESLGRPLWLSIILEIFSDSHLTRSFCLYSVSKQQQQKCMEPSSCRKTSSGLRTPTDYTLCRAIKTNQDLLPETPWTHIFYNDF
WGTLLTHSGSHKSYRPLCTLSFRLNHAIGGLNPWSYHLVNVLLHAAVTGLFTSFSKILLGDGYWTFMAGLMFASHPIHTEAVAGIVGRAD
VGASLFFLLSLLCYIKHCSTRGYSARTWGWFLGSGLCAGCSMLWKEQGVTVLAVSAVYDVFVFHRLKIKQILPTIYKRKNLSLFLSISLL
IFWGSSLLGARLYWMGNKPPSFSNSDNPAADSDSLLTRTLTFFYLPTKNLWLLLCPDTLSFDWSMDAVPLLKTVCDWRNLHTVAFYTGLL
LLAYYGLKSPSVDRECNGKTVTNGKQNANGHSCLSDVEYQNSETKSSFASKVENGIKNDVSQRTQLPSTENIVVLSLSLLIIPFVPATNL
FFYVGFVIAERVLYIPSMGFCLLITVGARALYVKVQKRFLKSLIFYATATLIVFYGLKTAIRNGDWQNEEMLYRSGIKVNPAKAWGNLGN
VLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIP
DENLKDPHAHKSSVTSCLYNLGKLYHEQGHYEEALSVYKEAIQKMPRQFAPQSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHL
TYGKLLALTGRKSEAEKLFLKAIELDPTKGNCYMHYGQFLLEEARLIEAAEMAKKAAELDSTEFDVVFNAAHMLRQASLNEAAEKYYDLA
ARLRPNEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHK
ALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQE
LLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLE
NELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQRE
KMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIP
RTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETIFSSM
DLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTP
KLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRALRMTHTLPSSYHNDARSSLSVSLEPESLGLGSAN
SSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVA
WLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAK
TKESEEGSWAQCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLN
YDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TMTC2-PPFIA2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TMTC2-PPFIA2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TMTC2-PPFIA2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource