FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:TMX2-ARHGAP4 (FusionGDB2 ID:92556)

Fusion Gene Summary for TMX2-ARHGAP4

check button Fusion gene summary
Fusion gene informationFusion gene name: TMX2-ARHGAP4
Fusion gene ID: 92556
HgeneTgene
Gene symbol

TMX2

ARHGAP4

Gene ID

51075

393

Gene namethioredoxin related transmembrane protein 2Rho GTPase activating protein 4
SynonymsCGI-31|NEDMCMS|PDIA12|PIG26|TXNDC14C1|RGC1|RhoGAP4|SrGAP4|p115
Cytomap

11q12.1

Xq28

Type of geneprotein-codingprotein-coding
Descriptionthioredoxin-related transmembrane protein 2cell proliferation-inducing gene 26 proteingrowth-inhibiting gene 11protein disulfide isomerase family A, member 12thioredoxin domain-containing protein 14rho GTPase-activating protein 4Rho-GAP hematopoietic protein C1rho-type GTPase-activating protein 4
Modification date2020031320200320
UniProtAcc.

Q92619

Ensembl transtripts involved in fusion geneENST00000278422, ENST00000378312, 
ENST00000467421, ENST00000350060, 
ENST00000370016, ENST00000370028, 
ENST00000393721, ENST00000537206, 
Fusion gene scores* DoF score9 X 3 X 9=2434 X 6 X 3=72
# samples 167
** MAII scorelog2(16/243*10)=-0.602884408718418
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/72*10)=-0.0406419844973459
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TMX2 [Title/Abstract] AND ARHGAP4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTMX2(57480279)-ARHGAP4(153179333), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across TMX2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ARHGAP4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-24-1426TMX2chr11

57480279

+ARHGAP4chrX

153179333

-


Top

Fusion Gene ORF analysis for TMX2-ARHGAP4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000278422ENST00000467421TMX2chr11

57480279

+ARHGAP4chrX

153179333

-
5CDS-intronENST00000378312ENST00000467421TMX2chr11

57480279

+ARHGAP4chrX

153179333

-
In-frameENST00000278422ENST00000350060TMX2chr11

57480279

+ARHGAP4chrX

153179333

-
In-frameENST00000278422ENST00000370016TMX2chr11

57480279

+ARHGAP4chrX

153179333

-
In-frameENST00000278422ENST00000370028TMX2chr11

57480279

+ARHGAP4chrX

153179333

-
In-frameENST00000278422ENST00000393721TMX2chr11

57480279

+ARHGAP4chrX

153179333

-
In-frameENST00000278422ENST00000537206TMX2chr11

57480279

+ARHGAP4chrX

153179333

-
In-frameENST00000378312ENST00000350060TMX2chr11

57480279

+ARHGAP4chrX

153179333

-
In-frameENST00000378312ENST00000370016TMX2chr11

57480279

+ARHGAP4chrX

153179333

-
In-frameENST00000378312ENST00000370028TMX2chr11

57480279

+ARHGAP4chrX

153179333

-
In-frameENST00000378312ENST00000393721TMX2chr11

57480279

+ARHGAP4chrX

153179333

-
In-frameENST00000378312ENST00000537206TMX2chr11

57480279

+ARHGAP4chrX

153179333

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000378312TMX2chr1157480279+ENST00000393721ARHGAP4chrX153179333-2376205162013665
ENST00000378312TMX2chr1157480279+ENST00000370028ARHGAP4chrX153179333-2367205162013665
ENST00000378312TMX2chr1157480279+ENST00000350060ARHGAP4chrX153179333-2366205162013665
ENST00000378312TMX2chr1157480279+ENST00000370016ARHGAP4chrX153179333-2289205162013665
ENST00000378312TMX2chr1157480279+ENST00000537206ARHGAP4chrX153179333-2177205162013665
ENST00000278422TMX2chr1157480279+ENST00000393721ARHGAP4chrX153179333-2372201122009665
ENST00000278422TMX2chr1157480279+ENST00000370028ARHGAP4chrX153179333-2363201122009665
ENST00000278422TMX2chr1157480279+ENST00000350060ARHGAP4chrX153179333-2362201122009665
ENST00000278422TMX2chr1157480279+ENST00000370016ARHGAP4chrX153179333-2285201122009665
ENST00000278422TMX2chr1157480279+ENST00000537206ARHGAP4chrX153179333-2173201122009665

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000378312ENST00000393721TMX2chr1157480279+ARHGAP4chrX153179333-0.0148455060.98515445
ENST00000378312ENST00000370028TMX2chr1157480279+ARHGAP4chrX153179333-0.0145980120.985402
ENST00000378312ENST00000350060TMX2chr1157480279+ARHGAP4chrX153179333-0.0146075010.9853925
ENST00000378312ENST00000370016TMX2chr1157480279+ARHGAP4chrX153179333-0.0151325270.9848675
ENST00000378312ENST00000537206TMX2chr1157480279+ARHGAP4chrX153179333-0.013266290.9867337
ENST00000278422ENST00000393721TMX2chr1157480279+ARHGAP4chrX153179333-0.0156280680.98437196
ENST00000278422ENST00000370028TMX2chr1157480279+ARHGAP4chrX153179333-0.0153954180.98460466
ENST00000278422ENST00000350060TMX2chr1157480279+ARHGAP4chrX153179333-0.0154062990.98459363
ENST00000278422ENST00000370016TMX2chr1157480279+ARHGAP4chrX153179333-0.0160501750.9839498
ENST00000278422ENST00000537206TMX2chr1157480279+ARHGAP4chrX153179333-0.0140619290.98593813

Top

Fusion Genomic Features for TMX2-ARHGAP4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for TMX2-ARHGAP4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:57480279/chrX:153179333)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ARHGAP4

Q92619

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR-domin which is able to play an autoinhibitory effect on this RhoGAP activity. {ECO:0000269|PubMed:24086303}.; FUNCTION: Precursor of the histocompatibility antigen HA-1. More generally, minor histocompatibility antigens (mHags) refer to immunogenic peptide which, when complexed with MHC, can generate an immune response after recognition by specific T-cells. The peptides are derived from polymorphic intracellular proteins, which are cleaved by normal pathways of antigen processing. The binding of these peptides to MHC class I or class II molecules and its expression on the cell surface can stimulate T-cell responses and thereby trigger graft rejection or graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation from HLA-identical sibling donor. GVHD is a frequent complication after bone marrow transplantation (BMT), due to mismatch of minor histocompatibility antigen in HLA-matched sibling marrow transplants. Specifically, mismatching for mHag HA-1 which is recognized as immunodominant, is shown to be associated with the development of severe GVHD after HLA-identical BMT. HA-1 is presented to the cell surface by MHC class I HLA-A*0201, but also by other HLA-A alleles. This complex specifically elicits donor-cytotoxic T-lymphocyte (CTL) reactivity against hematologic malignancies after treatment by HLA-identical allogenic BMT. It induces cell recognition and lysis by CTL. {ECO:0000269|PubMed:12601144, ECO:0000269|PubMed:8260714, ECO:0000269|PubMed:8532022, ECO:0000269|PubMed:9798702}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneARHGAP4chr11:57480279chrX:153179333ENST00000350060622507_695344947.0DomainRho-GAP
TgeneARHGAP4chr11:57480279chrX:153179333ENST00000350060622746_805344947.0DomainSH3
TgeneARHGAP4chr11:57480279chrX:153179333ENST00000370028723507_695384987.0DomainRho-GAP
TgeneARHGAP4chr11:57480279chrX:153179333ENST00000370028723746_805384987.0DomainSH3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTMX2chr11:57480279chrX:153179333ENST00000278422+18114_26963297.0DomainThioredoxin
HgeneTMX2chr11:57480279chrX:153179333ENST00000378312+17114_26963259.0DomainThioredoxin
HgeneTMX2chr11:57480279chrX:153179333ENST00000278422+18293_29663297.0MotifDi-lysine motif
HgeneTMX2chr11:57480279chrX:153179333ENST00000378312+17293_29663259.0MotifDi-lysine motif
HgeneTMX2chr11:57480279chrX:153179333ENST00000278422+18126_29663297.0Topological domainCytoplasmic
HgeneTMX2chr11:57480279chrX:153179333ENST00000278422+1849_10263297.0Topological domainExtracellular
HgeneTMX2chr11:57480279chrX:153179333ENST00000378312+17126_29663259.0Topological domainCytoplasmic
HgeneTMX2chr11:57480279chrX:153179333ENST00000378312+1749_10263259.0Topological domainExtracellular
HgeneTMX2chr11:57480279chrX:153179333ENST00000278422+18103_12563297.0TransmembraneHelical
HgeneTMX2chr11:57480279chrX:153179333ENST00000378312+17103_12563259.0TransmembraneHelical
TgeneARHGAP4chr11:57480279chrX:153179333ENST00000350060622128_195344947.0Coiled coilOntology_term=ECO:0000255
TgeneARHGAP4chr11:57480279chrX:153179333ENST00000370028723128_195384987.0Coiled coilOntology_term=ECO:0000255
TgeneARHGAP4chr11:57480279chrX:153179333ENST0000035006062219_317344947.0DomainF-BAR
TgeneARHGAP4chr11:57480279chrX:153179333ENST0000037002872319_317384987.0DomainF-BAR


Top

Fusion Gene Sequence for TMX2-ARHGAP4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>92556_92556_1_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000278422_ARHGAP4_chrX_153179333_ENST00000350060_length(transcript)=2362nt_BP=201nt
ACGGCCGAAAAGATGGCGGTCTTGGCACCTCTAATTGCTCTCGTGTATTCGGTGCCGCGACTTTCACGATGGCTCGCCCAACCTTACTAC
CTTCTGTCGGCCCTGCTCTCTGCTGCCTTCCTACTCGTGAGGAAACTGCCGCCGCTCTGCCACGGTCTGCCCACCCAACGCGAAGACGGT
AACCCGTGTGACTTTGACTGGGTGGCTGAGATCTGCGTTGAAATGGAGCTGCGGGACGAGATTCTGCCCAGAGCCCAGAACATCCAGAGC
CGCCTGGACCGACAGACCATTGAGACAGAGGAGGTGAACAAGACTCTGAAGGCGACACTGCAGGCCCTGCTGGAGGTGGTGGCCTCGGAT
GACGGGGATGTGCTTGATTCCTTCCAGACCAGCCCCTCCACCGAGTCCCTCAAGTCCACCAGCTCAGACCCAGGCAGCCGGCAGGCGGGC
CGGAGGCGCGGCCAGCAGCAGGAGACCGAAACCTTCTACCTCACGAAGCTCCAGGAGTATCTGAGTGGACGGAGCATCCTCGCCAAGCTG
CAGGCCAAGCACGAGAAGCTGCAGGAGGCCCTTCAGCGAGGTGACAAGGAGGAGCAGGAGGTGTCTTGGACCCAGTACACACAGAGAAAA
TTCCAGAAGAGCCGCCAGCCCCGCCCCAGCTCCCAGTATAACCAGAGACTCTTTGGGGGAGACATGGAGAAGTTTATCCAGAGCTCAGGC
CAGCCTGTGCCCCTGGTGGTGGAGAGCTGCATTCGCTTCATCAACCTCAATGGCCTGCAGCATGAAGGCATCTTCCGGGTATCGGGTGCC
CAGCTCCGGGTCTCAGAGATCCGTGATGCCTTCGAGAGAGGGGAGGACCCACTGGTGGAGGGCTGCACTGCCCATGACCTGGACTCGGTG
GCCGGGGTGCTGAAGCTCTACTTCCGGAGCCTGGAGCCCCCACTCTTCCCCCCAGACCTGTTCGGCGAGCTGCTGGCTTCTTCGGAGCTG
GAGGCCACAGCGGAGAGGGTGGAGCACGTGAGCCGCCTGCTGTGGCGGCTGCCCGCGCCGGTGCTGGTGGTTCTGCGCTACCTCTTCACC
TTCCTCAACCACCTGGCCCAGTACAGCGATGAGAACATGATGGACCCCTACAACCTGGCCGTGTGCTTCGGGCCCACGCTGCTACCGGTG
CCCGCTGGGCAGGACCCGGTGGCGCTGCAGGGCCGGGTGAACCAGCTGGTGCAGACGCTCATAGTGCAGCCCGATCGGGTCTTCCCGCCC
CTGACCTCGCTGCCTGGCCCCGTCTACGAGAAGTGCATGGCACCGCCTTCCGCCAGCTGCCTGGGGGACGCCCAGCTGGAGAGCCTGGGG
GCGGACAATGAGCCGGAGCTGGAAGCCGAGATGCCCGCACAGGAGGATGACCTGGAGGGGGTCGTGGAGGCTGTGGCCTGCTTTGCCTAC
ACGGGCCGCACAGCCCAGGAGCTGAGCTTCCGGCGGGGGGACGTACTGCGGCTGCACGAGAGGGCCTCGAGCGACTGGTGGCGGGGGGAG
CACAACGGCATGCGGGGCCTCATCCCCCACAAGTATATCACGCTGCCCGCCGGGACGGAGAAGCAGGTGGTGGGCGCAGGGCTGCAGACT
GCAGGGGAGTCTGGGAGCAGTCCCGAGGGCCTCCTGGCATCGGAGCTGGTCCACCGGCCAGAGCCATGCACCTCACCTGAGGCCATGGGA
CCCTCTGGACACAGACGACGCTGCTTGGTCCCAGCCTCCCCAGAGCAACACGTGGAGGTGGATAAGGCTGTGGCACAGAACATGGACTCT
GTGTTTAAGGAGCTCTTGGGAAAGACCTCTGTCCGCCAGGGCCTTGGGCCAGCATCTACCACCTCTCCCAGTCCTGGGCCCCGAAGCCCA
AAGGCCCCGCCCAGCAGCCGCCTGGGCAGGAACAAAGGCTTCTCCCGGGGCCCTGGGGCCCCAGCCTCACCCTCAGCTTCCCACCCCCAG
GGCCTAGACACGACCCCCAAGCCACACTGAGGTGCCGCTGCTGGAGATGCGTGCCCCCGGCGGCTACCCGCTGGACCGGCCACTCTCCCC
AGCCCCCTTGCTTCTCTCCAGCCCTGTCCAGCAAGTGCAGGGTGCCTGCACTTCACCCTGTGCAGAGAGGTGGGATGGGGCCGTGCACAC
AGGGATGCCCGCTCCACATCCTGCCTGCCCCTCAGCCCTGGCCCAGGCCCCTTTTGGAGGCAGCTGAGGAAGGATGCTGGGGAAAGCCCT
CTTCTGCAGCTTTGTGGAAGGCTGATCAGTGGCTGCTGGGTGGCGGGTACCCTTGCTCAGATGCCTGGCAGGGCTGGGTGGCGATTCATA

>92556_92556_1_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000278422_ARHGAP4_chrX_153179333_ENST00000350060_length(amino acids)=665AA_BP=63
MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWVAEICVEMELRDEILPRAQNIQSRLDR
QTIETEEVNKTLKATLQALLEVVASDDGDVLDSFQTSPSTESLKSTSSDPGSRQAGRRRGQQQETETFYLTKLQEYLSGRSILAKLQAKH
EKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRV
SEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNH
LAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQPDRVFPPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNE
PELEAEMPAQEDDLEGVVEAVACFAYTGRTAQELSFRRGDVLRLHERASSDWWRGEHNGMRGLIPHKYITLPAGTEKQVVGAGLQTAGES
GSSPEGLLASELVHRPEPCTSPEAMGPSGHRRRCLVPASPEQHVEVDKAVAQNMDSVFKELLGKTSVRQGLGPASTTSPSPGPRSPKAPP

--------------------------------------------------------------
>92556_92556_2_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000278422_ARHGAP4_chrX_153179333_ENST00000370016_length(transcript)=2285nt_BP=201nt
ACGGCCGAAAAGATGGCGGTCTTGGCACCTCTAATTGCTCTCGTGTATTCGGTGCCGCGACTTTCACGATGGCTCGCCCAACCTTACTAC
CTTCTGTCGGCCCTGCTCTCTGCTGCCTTCCTACTCGTGAGGAAACTGCCGCCGCTCTGCCACGGTCTGCCCACCCAACGCGAAGACGGT
AACCCGTGTGACTTTGACTGGGTGGCTGAGATCTGCGTTGAAATGGAGCTGCGGGACGAGATTCTGCCCAGAGCCCAGAACATCCAGAGC
CGCCTGGACCGACAGACCATTGAGACAGAGGAGGTGAACAAGACTCTGAAGGCGACACTGCAGGCCCTGCTGGAGGTGGTGGCCTCGGAT
GACGGGGATGTGCTTGATTCCTTCCAGACCAGCCCCTCCACCGAGTCCCTCAAGTCCACCAGCTCAGACCCAGGCAGCCGGCAGGCGGGC
CGGAGGCGCGGCCAGCAGCAGGAGACCGAAACCTTCTACCTCACGAAGCTCCAGGAGTATCTGAGTGGACGGAGCATCCTCGCCAAGCTG
CAGGCCAAGCACGAGAAGCTGCAGGAGGCCCTTCAGCGAGGTGACAAGGAGGAGCAGGAGGTGTCTTGGACCCAGTACACACAGAGAAAA
TTCCAGAAGAGCCGCCAGCCCCGCCCCAGCTCCCAGTATAACCAGAGACTCTTTGGGGGAGACATGGAGAAGTTTATCCAGAGCTCAGGC
CAGCCTGTGCCCCTGGTGGTGGAGAGCTGCATTCGCTTCATCAACCTCAATGGCCTGCAGCATGAAGGCATCTTCCGGGTATCGGGTGCC
CAGCTCCGGGTCTCAGAGATCCGTGATGCCTTCGAGAGAGGGGAGGACCCACTGGTGGAGGGCTGCACTGCCCATGACCTGGACTCGGTG
GCCGGGGTGCTGAAGCTCTACTTCCGGAGCCTGGAGCCCCCACTCTTCCCCCCAGACCTGTTCGGCGAGCTGCTGGCTTCTTCGGAGCTG
GAGGCCACAGCGGAGAGGGTGGAGCACGTGAGCCGCCTGCTGTGGCGGCTGCCCGCGCCGGTGCTGGTGGTTCTGCGCTACCTCTTCACC
TTCCTCAACCACCTGGCCCAGTACAGCGATGAGAACATGATGGACCCCTACAACCTGGCCGTGTGCTTCGGGCCCACGCTGCTACCGGTG
CCCGCTGGGCAGGACCCGGTGGCGCTGCAGGGCCGGGTGAACCAGCTGGTGCAGACGCTCATAGTGCAGCCCGATCGGGTCTTCCCGCCC
CTGACCTCGCTGCCTGGCCCCGTCTACGAGAAGTGCATGGCACCGCCTTCCGCCAGCTGCCTGGGGGACGCCCAGCTGGAGAGCCTGGGG
GCGGACAATGAGCCGGAGCTGGAAGCCGAGATGCCCGCACAGGAGGATGACCTGGAGGGGGTCGTGGAGGCTGTGGCCTGCTTTGCCTAC
ACGGGCCGCACAGCCCAGGAGCTGAGCTTCCGGCGGGGGGACGTACTGCGGCTGCACGAGAGGGCCTCGAGCGACTGGTGGCGGGGGGAG
CACAACGGCATGCGGGGCCTCATCCCCCACAAGTATATCACGCTGCCCGCCGGGACGGAGAAGCAGGTGGTGGGCGCAGGGCTGCAGACT
GCAGGGGAGTCTGGGAGCAGTCCCGAGGGCCTCCTGGCATCGGAGCTGGTCCACCGGCCAGAGCCATGCACCTCACCTGAGGCCATGGGA
CCCTCTGGACACAGACGACGCTGCTTGGTCCCAGCCTCCCCAGAGCAACACGTGGAGGTGGATAAGGCTGTGGCACAGAACATGGACTCT
GTGTTTAAGGAGCTCTTGGGAAAGACCTCTGTCCGCCAGGGCCTTGGGCCAGCATCTACCACCTCTCCCAGTCCTGGGCCCCGAAGCCCA
AAGGCCCCGCCCAGCAGCCGCCTGGGCAGGAACAAAGGCTTCTCCCGGGGCCCTGGGGCCCCAGCCTCACCCTCAGCTTCCCACCCCCAG
GGCCTAGACACGACCCCCAAGCCACACTGAGGTGCCGCTGCTGGAGATGCGTGCCCCCGGCGGCTACCCGCTGGACCGGCCACTCTCCCC
AGCCCCCTTGCTTCTCTCCAGCCCTGTCCAGCAAGTGCAGGGTGCCTGCACTTCACCCTGTGCAGAGAGGTGGGATGGGGCCGTGCACAC
AGGGATGCCCGCTCCACATCCTGCCTGCCCCTCAGCCCTGGCCCAGGCCCCTTTTGGAGGCAGCTGAGGAAGGATGCTGGGGAAAGCCCT

>92556_92556_2_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000278422_ARHGAP4_chrX_153179333_ENST00000370016_length(amino acids)=665AA_BP=63
MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWVAEICVEMELRDEILPRAQNIQSRLDR
QTIETEEVNKTLKATLQALLEVVASDDGDVLDSFQTSPSTESLKSTSSDPGSRQAGRRRGQQQETETFYLTKLQEYLSGRSILAKLQAKH
EKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRV
SEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNH
LAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQPDRVFPPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNE
PELEAEMPAQEDDLEGVVEAVACFAYTGRTAQELSFRRGDVLRLHERASSDWWRGEHNGMRGLIPHKYITLPAGTEKQVVGAGLQTAGES
GSSPEGLLASELVHRPEPCTSPEAMGPSGHRRRCLVPASPEQHVEVDKAVAQNMDSVFKELLGKTSVRQGLGPASTTSPSPGPRSPKAPP

--------------------------------------------------------------
>92556_92556_3_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000278422_ARHGAP4_chrX_153179333_ENST00000370028_length(transcript)=2363nt_BP=201nt
ACGGCCGAAAAGATGGCGGTCTTGGCACCTCTAATTGCTCTCGTGTATTCGGTGCCGCGACTTTCACGATGGCTCGCCCAACCTTACTAC
CTTCTGTCGGCCCTGCTCTCTGCTGCCTTCCTACTCGTGAGGAAACTGCCGCCGCTCTGCCACGGTCTGCCCACCCAACGCGAAGACGGT
AACCCGTGTGACTTTGACTGGGTGGCTGAGATCTGCGTTGAAATGGAGCTGCGGGACGAGATTCTGCCCAGAGCCCAGAACATCCAGAGC
CGCCTGGACCGACAGACCATTGAGACAGAGGAGGTGAACAAGACTCTGAAGGCGACACTGCAGGCCCTGCTGGAGGTGGTGGCCTCGGAT
GACGGGGATGTGCTTGATTCCTTCCAGACCAGCCCCTCCACCGAGTCCCTCAAGTCCACCAGCTCAGACCCAGGCAGCCGGCAGGCGGGC
CGGAGGCGCGGCCAGCAGCAGGAGACCGAAACCTTCTACCTCACGAAGCTCCAGGAGTATCTGAGTGGACGGAGCATCCTCGCCAAGCTG
CAGGCCAAGCACGAGAAGCTGCAGGAGGCCCTTCAGCGAGGTGACAAGGAGGAGCAGGAGGTGTCTTGGACCCAGTACACACAGAGAAAA
TTCCAGAAGAGCCGCCAGCCCCGCCCCAGCTCCCAGTATAACCAGAGACTCTTTGGGGGAGACATGGAGAAGTTTATCCAGAGCTCAGGC
CAGCCTGTGCCCCTGGTGGTGGAGAGCTGCATTCGCTTCATCAACCTCAATGGCCTGCAGCATGAAGGCATCTTCCGGGTATCGGGTGCC
CAGCTCCGGGTCTCAGAGATCCGTGATGCCTTCGAGAGAGGGGAGGACCCACTGGTGGAGGGCTGCACTGCCCATGACCTGGACTCGGTG
GCCGGGGTGCTGAAGCTCTACTTCCGGAGCCTGGAGCCCCCACTCTTCCCCCCAGACCTGTTCGGCGAGCTGCTGGCTTCTTCGGAGCTG
GAGGCCACAGCGGAGAGGGTGGAGCACGTGAGCCGCCTGCTGTGGCGGCTGCCCGCGCCGGTGCTGGTGGTTCTGCGCTACCTCTTCACC
TTCCTCAACCACCTGGCCCAGTACAGCGATGAGAACATGATGGACCCCTACAACCTGGCCGTGTGCTTCGGGCCCACGCTGCTACCGGTG
CCCGCTGGGCAGGACCCGGTGGCGCTGCAGGGCCGGGTGAACCAGCTGGTGCAGACGCTCATAGTGCAGCCCGATCGGGTCTTCCCGCCC
CTGACCTCGCTGCCTGGCCCCGTCTACGAGAAGTGCATGGCACCGCCTTCCGCCAGCTGCCTGGGGGACGCCCAGCTGGAGAGCCTGGGG
GCGGACAATGAGCCGGAGCTGGAAGCCGAGATGCCCGCACAGGAGGATGACCTGGAGGGGGTCGTGGAGGCTGTGGCCTGCTTTGCCTAC
ACGGGCCGCACAGCCCAGGAGCTGAGCTTCCGGCGGGGGGACGTACTGCGGCTGCACGAGAGGGCCTCGAGCGACTGGTGGCGGGGGGAG
CACAACGGCATGCGGGGCCTCATCCCCCACAAGTATATCACGCTGCCCGCCGGGACGGAGAAGCAGGTGGTGGGCGCAGGGCTGCAGACT
GCAGGGGAGTCTGGGAGCAGTCCCGAGGGCCTCCTGGCATCGGAGCTGGTCCACCGGCCAGAGCCATGCACCTCACCTGAGGCCATGGGA
CCCTCTGGACACAGACGACGCTGCTTGGTCCCAGCCTCCCCAGAGCAACACGTGGAGGTGGATAAGGCTGTGGCACAGAACATGGACTCT
GTGTTTAAGGAGCTCTTGGGAAAGACCTCTGTCCGCCAGGGCCTTGGGCCAGCATCTACCACCTCTCCCAGTCCTGGGCCCCGAAGCCCA
AAGGCCCCGCCCAGCAGCCGCCTGGGCAGGAACAAAGGCTTCTCCCGGGGCCCTGGGGCCCCAGCCTCACCCTCAGCTTCCCACCCCCAG
GGCCTAGACACGACCCCCAAGCCACACTGAGGTGCCGCTGCTGGAGATGCGTGCCCCCGGCGGCTACCCGCTGGACCGGCCACTCTCCCC
AGCCCCCTTGCTTCTCTCCAGCCCTGTCCAGCAAGTGCAGGGTGCCTGCACTTCACCCTGTGCAGAGAGGTGGGATGGGGCCGTGCACAC
AGGGATGCCCGCTCCACATCCTGCCTGCCCCTCAGCCCTGGCCCAGGCCCCTTTTGGAGGCAGCTGAGGAAGGATGCTGGGGAAAGCCCT
CTTCTGCAGCTTTGTGGAAGGCTGATCAGTGGCTGCTGGGTGGCGGGTACCCTTGCTCAGATGCCTGGCAGGGCTGGGTGGCGATTCATA

>92556_92556_3_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000278422_ARHGAP4_chrX_153179333_ENST00000370028_length(amino acids)=665AA_BP=63
MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWVAEICVEMELRDEILPRAQNIQSRLDR
QTIETEEVNKTLKATLQALLEVVASDDGDVLDSFQTSPSTESLKSTSSDPGSRQAGRRRGQQQETETFYLTKLQEYLSGRSILAKLQAKH
EKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRV
SEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNH
LAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQPDRVFPPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNE
PELEAEMPAQEDDLEGVVEAVACFAYTGRTAQELSFRRGDVLRLHERASSDWWRGEHNGMRGLIPHKYITLPAGTEKQVVGAGLQTAGES
GSSPEGLLASELVHRPEPCTSPEAMGPSGHRRRCLVPASPEQHVEVDKAVAQNMDSVFKELLGKTSVRQGLGPASTTSPSPGPRSPKAPP

--------------------------------------------------------------
>92556_92556_4_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000278422_ARHGAP4_chrX_153179333_ENST00000393721_length(transcript)=2372nt_BP=201nt
ACGGCCGAAAAGATGGCGGTCTTGGCACCTCTAATTGCTCTCGTGTATTCGGTGCCGCGACTTTCACGATGGCTCGCCCAACCTTACTAC
CTTCTGTCGGCCCTGCTCTCTGCTGCCTTCCTACTCGTGAGGAAACTGCCGCCGCTCTGCCACGGTCTGCCCACCCAACGCGAAGACGGT
AACCCGTGTGACTTTGACTGGGTGGCTGAGATCTGCGTTGAAATGGAGCTGCGGGACGAGATTCTGCCCAGAGCCCAGAACATCCAGAGC
CGCCTGGACCGACAGACCATTGAGACAGAGGAGGTGAACAAGACTCTGAAGGCGACACTGCAGGCCCTGCTGGAGGTGGTGGCCTCGGAT
GACGGGGATGTGCTTGATTCCTTCCAGACCAGCCCCTCCACCGAGTCCCTCAAGTCCACCAGCTCAGACCCAGGCAGCCGGCAGGCGGGC
CGGAGGCGCGGCCAGCAGCAGGAGACCGAAACCTTCTACCTCACGAAGCTCCAGGAGTATCTGAGTGGACGGAGCATCCTCGCCAAGCTG
CAGGCCAAGCACGAGAAGCTGCAGGAGGCCCTTCAGCGAGGTGACAAGGAGGAGCAGGAGGTGTCTTGGACCCAGTACACACAGAGAAAA
TTCCAGAAGAGCCGCCAGCCCCGCCCCAGCTCCCAGTATAACCAGAGACTCTTTGGGGGAGACATGGAGAAGTTTATCCAGAGCTCAGGC
CAGCCTGTGCCCCTGGTGGTGGAGAGCTGCATTCGCTTCATCAACCTCAATGGCCTGCAGCATGAAGGCATCTTCCGGGTATCGGGTGCC
CAGCTCCGGGTCTCAGAGATCCGTGATGCCTTCGAGAGAGGGGAGGACCCACTGGTGGAGGGCTGCACTGCCCATGACCTGGACTCGGTG
GCCGGGGTGCTGAAGCTCTACTTCCGGAGCCTGGAGCCCCCACTCTTCCCCCCAGACCTGTTCGGCGAGCTGCTGGCTTCTTCGGAGCTG
GAGGCCACAGCGGAGAGGGTGGAGCACGTGAGCCGCCTGCTGTGGCGGCTGCCCGCGCCGGTGCTGGTGGTTCTGCGCTACCTCTTCACC
TTCCTCAACCACCTGGCCCAGTACAGCGATGAGAACATGATGGACCCCTACAACCTGGCCGTGTGCTTCGGGCCCACGCTGCTACCGGTG
CCCGCTGGGCAGGACCCGGTGGCGCTGCAGGGCCGGGTGAACCAGCTGGTGCAGACGCTCATAGTGCAGCCCGATCGGGTCTTCCCGCCC
CTGACCTCGCTGCCTGGCCCCGTCTACGAGAAGTGCATGGCACCGCCTTCCGCCAGCTGCCTGGGGGACGCCCAGCTGGAGAGCCTGGGG
GCGGACAATGAGCCGGAGCTGGAAGCCGAGATGCCCGCACAGGAGGATGACCTGGAGGGGGTCGTGGAGGCTGTGGCCTGCTTTGCCTAC
ACGGGCCGCACAGCCCAGGAGCTGAGCTTCCGGCGGGGGGACGTACTGCGGCTGCACGAGAGGGCCTCGAGCGACTGGTGGCGGGGGGAG
CACAACGGCATGCGGGGCCTCATCCCCCACAAGTATATCACGCTGCCCGCCGGGACGGAGAAGCAGGTGGTGGGCGCAGGGCTGCAGACT
GCAGGGGAGTCTGGGAGCAGTCCCGAGGGCCTCCTGGCATCGGAGCTGGTCCACCGGCCAGAGCCATGCACCTCACCTGAGGCCATGGGA
CCCTCTGGACACAGACGACGCTGCTTGGTCCCAGCCTCCCCAGAGCAACACGTGGAGGTGGATAAGGCTGTGGCACAGAACATGGACTCT
GTGTTTAAGGAGCTCTTGGGAAAGACCTCTGTCCGCCAGGGCCTTGGGCCAGCATCTACCACCTCTCCCAGTCCTGGGCCCCGAAGCCCA
AAGGCCCCGCCCAGCAGCCGCCTGGGCAGGAACAAAGGCTTCTCCCGGGGCCCTGGGGCCCCAGCCTCACCCTCAGCTTCCCACCCCCAG
GGCCTAGACACGACCCCCAAGCCACACTGAGGTGCCGCTGCTGGAGATGCGTGCCCCCGGCGGCTACCCGCTGGACCGGCCACTCTCCCC
AGCCCCCTTGCTTCTCTCCAGCCCTGTCCAGCAAGTGCAGGGTGCCTGCACTTCACCCTGTGCAGAGAGGTGGGATGGGGCCGTGCACAC
AGGGATGCCCGCTCCACATCCTGCCTGCCCCTCAGCCCTGGCCCAGGCCCCTTTTGGAGGCAGCTGAGGAAGGATGCTGGGGAAAGCCCT
CTTCTGCAGCTTTGTGGAAGGCTGATCAGTGGCTGCTGGGTGGCGGGTACCCTTGCTCAGATGCCTGGCAGGGCTGGGTGGCGATTCATA

>92556_92556_4_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000278422_ARHGAP4_chrX_153179333_ENST00000393721_length(amino acids)=665AA_BP=63
MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWVAEICVEMELRDEILPRAQNIQSRLDR
QTIETEEVNKTLKATLQALLEVVASDDGDVLDSFQTSPSTESLKSTSSDPGSRQAGRRRGQQQETETFYLTKLQEYLSGRSILAKLQAKH
EKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRV
SEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNH
LAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQPDRVFPPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNE
PELEAEMPAQEDDLEGVVEAVACFAYTGRTAQELSFRRGDVLRLHERASSDWWRGEHNGMRGLIPHKYITLPAGTEKQVVGAGLQTAGES
GSSPEGLLASELVHRPEPCTSPEAMGPSGHRRRCLVPASPEQHVEVDKAVAQNMDSVFKELLGKTSVRQGLGPASTTSPSPGPRSPKAPP

--------------------------------------------------------------
>92556_92556_5_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000278422_ARHGAP4_chrX_153179333_ENST00000537206_length(transcript)=2173nt_BP=201nt
ACGGCCGAAAAGATGGCGGTCTTGGCACCTCTAATTGCTCTCGTGTATTCGGTGCCGCGACTTTCACGATGGCTCGCCCAACCTTACTAC
CTTCTGTCGGCCCTGCTCTCTGCTGCCTTCCTACTCGTGAGGAAACTGCCGCCGCTCTGCCACGGTCTGCCCACCCAACGCGAAGACGGT
AACCCGTGTGACTTTGACTGGGTGGCTGAGATCTGCGTTGAAATGGAGCTGCGGGACGAGATTCTGCCCAGAGCCCAGAACATCCAGAGC
CGCCTGGACCGACAGACCATTGAGACAGAGGAGGTGAACAAGACTCTGAAGGCGACACTGCAGGCCCTGCTGGAGGTGGTGGCCTCGGAT
GACGGGGATGTGCTTGATTCCTTCCAGACCAGCCCCTCCACCGAGTCCCTCAAGTCCACCAGCTCAGACCCAGGCAGCCGGCAGGCGGGC
CGGAGGCGCGGCCAGCAGCAGGAGACCGAAACCTTCTACCTCACGAAGCTCCAGGAGTATCTGAGTGGACGGAGCATCCTCGCCAAGCTG
CAGGCCAAGCACGAGAAGCTGCAGGAGGCCCTTCAGCGAGGTGACAAGGAGGAGCAGGAGGTGTCTTGGACCCAGTACACACAGAGAAAA
TTCCAGAAGAGCCGCCAGCCCCGCCCCAGCTCCCAGTATAACCAGAGACTCTTTGGGGGAGACATGGAGAAGTTTATCCAGAGCTCAGGC
CAGCCTGTGCCCCTGGTGGTGGAGAGCTGCATTCGCTTCATCAACCTCAATGGCCTGCAGCATGAAGGCATCTTCCGGGTATCGGGTGCC
CAGCTCCGGGTCTCAGAGATCCGTGATGCCTTCGAGAGAGGGGAGGACCCACTGGTGGAGGGCTGCACTGCCCATGACCTGGACTCGGTG
GCCGGGGTGCTGAAGCTCTACTTCCGGAGCCTGGAGCCCCCACTCTTCCCCCCAGACCTGTTCGGCGAGCTGCTGGCTTCTTCGGAGCTG
GAGGCCACAGCGGAGAGGGTGGAGCACGTGAGCCGCCTGCTGTGGCGGCTGCCCGCGCCGGTGCTGGTGGTTCTGCGCTACCTCTTCACC
TTCCTCAACCACCTGGCCCAGTACAGCGATGAGAACATGATGGACCCCTACAACCTGGCCGTGTGCTTCGGGCCCACGCTGCTACCGGTG
CCCGCTGGGCAGGACCCGGTGGCGCTGCAGGGCCGGGTGAACCAGCTGGTGCAGACGCTCATAGTGCAGCCCGATCGGGTCTTCCCGCCC
CTGACCTCGCTGCCTGGCCCCGTCTACGAGAAGTGCATGGCACCGCCTTCCGCCAGCTGCCTGGGGGACGCCCAGCTGGAGAGCCTGGGG
GCGGACAATGAGCCGGAGCTGGAAGCCGAGATGCCCGCACAGGAGGATGACCTGGAGGGGGTCGTGGAGGCTGTGGCCTGCTTTGCCTAC
ACGGGCCGCACAGCCCAGGAGCTGAGCTTCCGGCGGGGGGACGTACTGCGGCTGCACGAGAGGGCCTCGAGCGACTGGTGGCGGGGGGAG
CACAACGGCATGCGGGGCCTCATCCCCCACAAGTATATCACGCTGCCCGCCGGGACGGAGAAGCAGGTGGTGGGCGCAGGGCTGCAGACT
GCAGGGGAGTCTGGGAGCAGTCCCGAGGGCCTCCTGGCATCGGAGCTGGTCCACCGGCCAGAGCCATGCACCTCACCTGAGGCCATGGGA
CCCTCTGGACACAGACGACGCTGCTTGGTCCCAGCCTCCCCAGAGCAACACGTGGAGGTGGATAAGGCTGTGGCACAGAACATGGACTCT
GTGTTTAAGGAGCTCTTGGGAAAGACCTCTGTCCGCCAGGGCCTTGGGCCAGCATCTACCACCTCTCCCAGTCCTGGGCCCCGAAGCCCA
AAGGCCCCGCCCAGCAGCCGCCTGGGCAGGAACAAAGGCTTCTCCCGGGGCCCTGGGGCCCCAGCCTCACCCTCAGCTTCCCACCCCCAG
GGCCTAGACACGACCCCCAAGCCACACTGAGGTGCCGCTGCTGGAGATGCGTGCCCCCGGCGGCTACCCGCTGGACCGGCCACTCTCCCC
AGCCCCCTTGCTTCTCTCCAGCCCTGTCCAGCAAGTGCAGGGTGCCTGCACTTCACCCTGTGCAGAGAGGTGGGATGGGGCCGTGCACAC

>92556_92556_5_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000278422_ARHGAP4_chrX_153179333_ENST00000537206_length(amino acids)=665AA_BP=63
MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWVAEICVEMELRDEILPRAQNIQSRLDR
QTIETEEVNKTLKATLQALLEVVASDDGDVLDSFQTSPSTESLKSTSSDPGSRQAGRRRGQQQETETFYLTKLQEYLSGRSILAKLQAKH
EKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRV
SEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNH
LAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQPDRVFPPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNE
PELEAEMPAQEDDLEGVVEAVACFAYTGRTAQELSFRRGDVLRLHERASSDWWRGEHNGMRGLIPHKYITLPAGTEKQVVGAGLQTAGES
GSSPEGLLASELVHRPEPCTSPEAMGPSGHRRRCLVPASPEQHVEVDKAVAQNMDSVFKELLGKTSVRQGLGPASTTSPSPGPRSPKAPP

--------------------------------------------------------------
>92556_92556_6_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000378312_ARHGAP4_chrX_153179333_ENST00000350060_length(transcript)=2366nt_BP=205nt
CGTTACGGCCGAAAAGATGGCGGTCTTGGCACCTCTAATTGCTCTCGTGTATTCGGTGCCGCGACTTTCACGATGGCTCGCCCAACCTTA
CTACCTTCTGTCGGCCCTGCTCTCTGCTGCCTTCCTACTCGTGAGGAAACTGCCGCCGCTCTGCCACGGTCTGCCCACCCAACGCGAAGA
CGGTAACCCGTGTGACTTTGACTGGGTGGCTGAGATCTGCGTTGAAATGGAGCTGCGGGACGAGATTCTGCCCAGAGCCCAGAACATCCA
GAGCCGCCTGGACCGACAGACCATTGAGACAGAGGAGGTGAACAAGACTCTGAAGGCGACACTGCAGGCCCTGCTGGAGGTGGTGGCCTC
GGATGACGGGGATGTGCTTGATTCCTTCCAGACCAGCCCCTCCACCGAGTCCCTCAAGTCCACCAGCTCAGACCCAGGCAGCCGGCAGGC
GGGCCGGAGGCGCGGCCAGCAGCAGGAGACCGAAACCTTCTACCTCACGAAGCTCCAGGAGTATCTGAGTGGACGGAGCATCCTCGCCAA
GCTGCAGGCCAAGCACGAGAAGCTGCAGGAGGCCCTTCAGCGAGGTGACAAGGAGGAGCAGGAGGTGTCTTGGACCCAGTACACACAGAG
AAAATTCCAGAAGAGCCGCCAGCCCCGCCCCAGCTCCCAGTATAACCAGAGACTCTTTGGGGGAGACATGGAGAAGTTTATCCAGAGCTC
AGGCCAGCCTGTGCCCCTGGTGGTGGAGAGCTGCATTCGCTTCATCAACCTCAATGGCCTGCAGCATGAAGGCATCTTCCGGGTATCGGG
TGCCCAGCTCCGGGTCTCAGAGATCCGTGATGCCTTCGAGAGAGGGGAGGACCCACTGGTGGAGGGCTGCACTGCCCATGACCTGGACTC
GGTGGCCGGGGTGCTGAAGCTCTACTTCCGGAGCCTGGAGCCCCCACTCTTCCCCCCAGACCTGTTCGGCGAGCTGCTGGCTTCTTCGGA
GCTGGAGGCCACAGCGGAGAGGGTGGAGCACGTGAGCCGCCTGCTGTGGCGGCTGCCCGCGCCGGTGCTGGTGGTTCTGCGCTACCTCTT
CACCTTCCTCAACCACCTGGCCCAGTACAGCGATGAGAACATGATGGACCCCTACAACCTGGCCGTGTGCTTCGGGCCCACGCTGCTACC
GGTGCCCGCTGGGCAGGACCCGGTGGCGCTGCAGGGCCGGGTGAACCAGCTGGTGCAGACGCTCATAGTGCAGCCCGATCGGGTCTTCCC
GCCCCTGACCTCGCTGCCTGGCCCCGTCTACGAGAAGTGCATGGCACCGCCTTCCGCCAGCTGCCTGGGGGACGCCCAGCTGGAGAGCCT
GGGGGCGGACAATGAGCCGGAGCTGGAAGCCGAGATGCCCGCACAGGAGGATGACCTGGAGGGGGTCGTGGAGGCTGTGGCCTGCTTTGC
CTACACGGGCCGCACAGCCCAGGAGCTGAGCTTCCGGCGGGGGGACGTACTGCGGCTGCACGAGAGGGCCTCGAGCGACTGGTGGCGGGG
GGAGCACAACGGCATGCGGGGCCTCATCCCCCACAAGTATATCACGCTGCCCGCCGGGACGGAGAAGCAGGTGGTGGGCGCAGGGCTGCA
GACTGCAGGGGAGTCTGGGAGCAGTCCCGAGGGCCTCCTGGCATCGGAGCTGGTCCACCGGCCAGAGCCATGCACCTCACCTGAGGCCAT
GGGACCCTCTGGACACAGACGACGCTGCTTGGTCCCAGCCTCCCCAGAGCAACACGTGGAGGTGGATAAGGCTGTGGCACAGAACATGGA
CTCTGTGTTTAAGGAGCTCTTGGGAAAGACCTCTGTCCGCCAGGGCCTTGGGCCAGCATCTACCACCTCTCCCAGTCCTGGGCCCCGAAG
CCCAAAGGCCCCGCCCAGCAGCCGCCTGGGCAGGAACAAAGGCTTCTCCCGGGGCCCTGGGGCCCCAGCCTCACCCTCAGCTTCCCACCC
CCAGGGCCTAGACACGACCCCCAAGCCACACTGAGGTGCCGCTGCTGGAGATGCGTGCCCCCGGCGGCTACCCGCTGGACCGGCCACTCT
CCCCAGCCCCCTTGCTTCTCTCCAGCCCTGTCCAGCAAGTGCAGGGTGCCTGCACTTCACCCTGTGCAGAGAGGTGGGATGGGGCCGTGC
ACACAGGGATGCCCGCTCCACATCCTGCCTGCCCCTCAGCCCTGGCCCAGGCCCCTTTTGGAGGCAGCTGAGGAAGGATGCTGGGGAAAG
CCCTCTTCTGCAGCTTTGTGGAAGGCTGATCAGTGGCTGCTGGGTGGCGGGTACCCTTGCTCAGATGCCTGGCAGGGCTGGGTGGCGATT

>92556_92556_6_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000378312_ARHGAP4_chrX_153179333_ENST00000350060_length(amino acids)=665AA_BP=63
MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWVAEICVEMELRDEILPRAQNIQSRLDR
QTIETEEVNKTLKATLQALLEVVASDDGDVLDSFQTSPSTESLKSTSSDPGSRQAGRRRGQQQETETFYLTKLQEYLSGRSILAKLQAKH
EKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRV
SEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNH
LAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQPDRVFPPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNE
PELEAEMPAQEDDLEGVVEAVACFAYTGRTAQELSFRRGDVLRLHERASSDWWRGEHNGMRGLIPHKYITLPAGTEKQVVGAGLQTAGES
GSSPEGLLASELVHRPEPCTSPEAMGPSGHRRRCLVPASPEQHVEVDKAVAQNMDSVFKELLGKTSVRQGLGPASTTSPSPGPRSPKAPP

--------------------------------------------------------------
>92556_92556_7_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000378312_ARHGAP4_chrX_153179333_ENST00000370016_length(transcript)=2289nt_BP=205nt
CGTTACGGCCGAAAAGATGGCGGTCTTGGCACCTCTAATTGCTCTCGTGTATTCGGTGCCGCGACTTTCACGATGGCTCGCCCAACCTTA
CTACCTTCTGTCGGCCCTGCTCTCTGCTGCCTTCCTACTCGTGAGGAAACTGCCGCCGCTCTGCCACGGTCTGCCCACCCAACGCGAAGA
CGGTAACCCGTGTGACTTTGACTGGGTGGCTGAGATCTGCGTTGAAATGGAGCTGCGGGACGAGATTCTGCCCAGAGCCCAGAACATCCA
GAGCCGCCTGGACCGACAGACCATTGAGACAGAGGAGGTGAACAAGACTCTGAAGGCGACACTGCAGGCCCTGCTGGAGGTGGTGGCCTC
GGATGACGGGGATGTGCTTGATTCCTTCCAGACCAGCCCCTCCACCGAGTCCCTCAAGTCCACCAGCTCAGACCCAGGCAGCCGGCAGGC
GGGCCGGAGGCGCGGCCAGCAGCAGGAGACCGAAACCTTCTACCTCACGAAGCTCCAGGAGTATCTGAGTGGACGGAGCATCCTCGCCAA
GCTGCAGGCCAAGCACGAGAAGCTGCAGGAGGCCCTTCAGCGAGGTGACAAGGAGGAGCAGGAGGTGTCTTGGACCCAGTACACACAGAG
AAAATTCCAGAAGAGCCGCCAGCCCCGCCCCAGCTCCCAGTATAACCAGAGACTCTTTGGGGGAGACATGGAGAAGTTTATCCAGAGCTC
AGGCCAGCCTGTGCCCCTGGTGGTGGAGAGCTGCATTCGCTTCATCAACCTCAATGGCCTGCAGCATGAAGGCATCTTCCGGGTATCGGG
TGCCCAGCTCCGGGTCTCAGAGATCCGTGATGCCTTCGAGAGAGGGGAGGACCCACTGGTGGAGGGCTGCACTGCCCATGACCTGGACTC
GGTGGCCGGGGTGCTGAAGCTCTACTTCCGGAGCCTGGAGCCCCCACTCTTCCCCCCAGACCTGTTCGGCGAGCTGCTGGCTTCTTCGGA
GCTGGAGGCCACAGCGGAGAGGGTGGAGCACGTGAGCCGCCTGCTGTGGCGGCTGCCCGCGCCGGTGCTGGTGGTTCTGCGCTACCTCTT
CACCTTCCTCAACCACCTGGCCCAGTACAGCGATGAGAACATGATGGACCCCTACAACCTGGCCGTGTGCTTCGGGCCCACGCTGCTACC
GGTGCCCGCTGGGCAGGACCCGGTGGCGCTGCAGGGCCGGGTGAACCAGCTGGTGCAGACGCTCATAGTGCAGCCCGATCGGGTCTTCCC
GCCCCTGACCTCGCTGCCTGGCCCCGTCTACGAGAAGTGCATGGCACCGCCTTCCGCCAGCTGCCTGGGGGACGCCCAGCTGGAGAGCCT
GGGGGCGGACAATGAGCCGGAGCTGGAAGCCGAGATGCCCGCACAGGAGGATGACCTGGAGGGGGTCGTGGAGGCTGTGGCCTGCTTTGC
CTACACGGGCCGCACAGCCCAGGAGCTGAGCTTCCGGCGGGGGGACGTACTGCGGCTGCACGAGAGGGCCTCGAGCGACTGGTGGCGGGG
GGAGCACAACGGCATGCGGGGCCTCATCCCCCACAAGTATATCACGCTGCCCGCCGGGACGGAGAAGCAGGTGGTGGGCGCAGGGCTGCA
GACTGCAGGGGAGTCTGGGAGCAGTCCCGAGGGCCTCCTGGCATCGGAGCTGGTCCACCGGCCAGAGCCATGCACCTCACCTGAGGCCAT
GGGACCCTCTGGACACAGACGACGCTGCTTGGTCCCAGCCTCCCCAGAGCAACACGTGGAGGTGGATAAGGCTGTGGCACAGAACATGGA
CTCTGTGTTTAAGGAGCTCTTGGGAAAGACCTCTGTCCGCCAGGGCCTTGGGCCAGCATCTACCACCTCTCCCAGTCCTGGGCCCCGAAG
CCCAAAGGCCCCGCCCAGCAGCCGCCTGGGCAGGAACAAAGGCTTCTCCCGGGGCCCTGGGGCCCCAGCCTCACCCTCAGCTTCCCACCC
CCAGGGCCTAGACACGACCCCCAAGCCACACTGAGGTGCCGCTGCTGGAGATGCGTGCCCCCGGCGGCTACCCGCTGGACCGGCCACTCT
CCCCAGCCCCCTTGCTTCTCTCCAGCCCTGTCCAGCAAGTGCAGGGTGCCTGCACTTCACCCTGTGCAGAGAGGTGGGATGGGGCCGTGC
ACACAGGGATGCCCGCTCCACATCCTGCCTGCCCCTCAGCCCTGGCCCAGGCCCCTTTTGGAGGCAGCTGAGGAAGGATGCTGGGGAAAG

>92556_92556_7_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000378312_ARHGAP4_chrX_153179333_ENST00000370016_length(amino acids)=665AA_BP=63
MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWVAEICVEMELRDEILPRAQNIQSRLDR
QTIETEEVNKTLKATLQALLEVVASDDGDVLDSFQTSPSTESLKSTSSDPGSRQAGRRRGQQQETETFYLTKLQEYLSGRSILAKLQAKH
EKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRV
SEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNH
LAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQPDRVFPPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNE
PELEAEMPAQEDDLEGVVEAVACFAYTGRTAQELSFRRGDVLRLHERASSDWWRGEHNGMRGLIPHKYITLPAGTEKQVVGAGLQTAGES
GSSPEGLLASELVHRPEPCTSPEAMGPSGHRRRCLVPASPEQHVEVDKAVAQNMDSVFKELLGKTSVRQGLGPASTTSPSPGPRSPKAPP

--------------------------------------------------------------
>92556_92556_8_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000378312_ARHGAP4_chrX_153179333_ENST00000370028_length(transcript)=2367nt_BP=205nt
CGTTACGGCCGAAAAGATGGCGGTCTTGGCACCTCTAATTGCTCTCGTGTATTCGGTGCCGCGACTTTCACGATGGCTCGCCCAACCTTA
CTACCTTCTGTCGGCCCTGCTCTCTGCTGCCTTCCTACTCGTGAGGAAACTGCCGCCGCTCTGCCACGGTCTGCCCACCCAACGCGAAGA
CGGTAACCCGTGTGACTTTGACTGGGTGGCTGAGATCTGCGTTGAAATGGAGCTGCGGGACGAGATTCTGCCCAGAGCCCAGAACATCCA
GAGCCGCCTGGACCGACAGACCATTGAGACAGAGGAGGTGAACAAGACTCTGAAGGCGACACTGCAGGCCCTGCTGGAGGTGGTGGCCTC
GGATGACGGGGATGTGCTTGATTCCTTCCAGACCAGCCCCTCCACCGAGTCCCTCAAGTCCACCAGCTCAGACCCAGGCAGCCGGCAGGC
GGGCCGGAGGCGCGGCCAGCAGCAGGAGACCGAAACCTTCTACCTCACGAAGCTCCAGGAGTATCTGAGTGGACGGAGCATCCTCGCCAA
GCTGCAGGCCAAGCACGAGAAGCTGCAGGAGGCCCTTCAGCGAGGTGACAAGGAGGAGCAGGAGGTGTCTTGGACCCAGTACACACAGAG
AAAATTCCAGAAGAGCCGCCAGCCCCGCCCCAGCTCCCAGTATAACCAGAGACTCTTTGGGGGAGACATGGAGAAGTTTATCCAGAGCTC
AGGCCAGCCTGTGCCCCTGGTGGTGGAGAGCTGCATTCGCTTCATCAACCTCAATGGCCTGCAGCATGAAGGCATCTTCCGGGTATCGGG
TGCCCAGCTCCGGGTCTCAGAGATCCGTGATGCCTTCGAGAGAGGGGAGGACCCACTGGTGGAGGGCTGCACTGCCCATGACCTGGACTC
GGTGGCCGGGGTGCTGAAGCTCTACTTCCGGAGCCTGGAGCCCCCACTCTTCCCCCCAGACCTGTTCGGCGAGCTGCTGGCTTCTTCGGA
GCTGGAGGCCACAGCGGAGAGGGTGGAGCACGTGAGCCGCCTGCTGTGGCGGCTGCCCGCGCCGGTGCTGGTGGTTCTGCGCTACCTCTT
CACCTTCCTCAACCACCTGGCCCAGTACAGCGATGAGAACATGATGGACCCCTACAACCTGGCCGTGTGCTTCGGGCCCACGCTGCTACC
GGTGCCCGCTGGGCAGGACCCGGTGGCGCTGCAGGGCCGGGTGAACCAGCTGGTGCAGACGCTCATAGTGCAGCCCGATCGGGTCTTCCC
GCCCCTGACCTCGCTGCCTGGCCCCGTCTACGAGAAGTGCATGGCACCGCCTTCCGCCAGCTGCCTGGGGGACGCCCAGCTGGAGAGCCT
GGGGGCGGACAATGAGCCGGAGCTGGAAGCCGAGATGCCCGCACAGGAGGATGACCTGGAGGGGGTCGTGGAGGCTGTGGCCTGCTTTGC
CTACACGGGCCGCACAGCCCAGGAGCTGAGCTTCCGGCGGGGGGACGTACTGCGGCTGCACGAGAGGGCCTCGAGCGACTGGTGGCGGGG
GGAGCACAACGGCATGCGGGGCCTCATCCCCCACAAGTATATCACGCTGCCCGCCGGGACGGAGAAGCAGGTGGTGGGCGCAGGGCTGCA
GACTGCAGGGGAGTCTGGGAGCAGTCCCGAGGGCCTCCTGGCATCGGAGCTGGTCCACCGGCCAGAGCCATGCACCTCACCTGAGGCCAT
GGGACCCTCTGGACACAGACGACGCTGCTTGGTCCCAGCCTCCCCAGAGCAACACGTGGAGGTGGATAAGGCTGTGGCACAGAACATGGA
CTCTGTGTTTAAGGAGCTCTTGGGAAAGACCTCTGTCCGCCAGGGCCTTGGGCCAGCATCTACCACCTCTCCCAGTCCTGGGCCCCGAAG
CCCAAAGGCCCCGCCCAGCAGCCGCCTGGGCAGGAACAAAGGCTTCTCCCGGGGCCCTGGGGCCCCAGCCTCACCCTCAGCTTCCCACCC
CCAGGGCCTAGACACGACCCCCAAGCCACACTGAGGTGCCGCTGCTGGAGATGCGTGCCCCCGGCGGCTACCCGCTGGACCGGCCACTCT
CCCCAGCCCCCTTGCTTCTCTCCAGCCCTGTCCAGCAAGTGCAGGGTGCCTGCACTTCACCCTGTGCAGAGAGGTGGGATGGGGCCGTGC
ACACAGGGATGCCCGCTCCACATCCTGCCTGCCCCTCAGCCCTGGCCCAGGCCCCTTTTGGAGGCAGCTGAGGAAGGATGCTGGGGAAAG
CCCTCTTCTGCAGCTTTGTGGAAGGCTGATCAGTGGCTGCTGGGTGGCGGGTACCCTTGCTCAGATGCCTGGCAGGGCTGGGTGGCGATT

>92556_92556_8_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000378312_ARHGAP4_chrX_153179333_ENST00000370028_length(amino acids)=665AA_BP=63
MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWVAEICVEMELRDEILPRAQNIQSRLDR
QTIETEEVNKTLKATLQALLEVVASDDGDVLDSFQTSPSTESLKSTSSDPGSRQAGRRRGQQQETETFYLTKLQEYLSGRSILAKLQAKH
EKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRV
SEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNH
LAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQPDRVFPPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNE
PELEAEMPAQEDDLEGVVEAVACFAYTGRTAQELSFRRGDVLRLHERASSDWWRGEHNGMRGLIPHKYITLPAGTEKQVVGAGLQTAGES
GSSPEGLLASELVHRPEPCTSPEAMGPSGHRRRCLVPASPEQHVEVDKAVAQNMDSVFKELLGKTSVRQGLGPASTTSPSPGPRSPKAPP

--------------------------------------------------------------
>92556_92556_9_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000378312_ARHGAP4_chrX_153179333_ENST00000393721_length(transcript)=2376nt_BP=205nt
CGTTACGGCCGAAAAGATGGCGGTCTTGGCACCTCTAATTGCTCTCGTGTATTCGGTGCCGCGACTTTCACGATGGCTCGCCCAACCTTA
CTACCTTCTGTCGGCCCTGCTCTCTGCTGCCTTCCTACTCGTGAGGAAACTGCCGCCGCTCTGCCACGGTCTGCCCACCCAACGCGAAGA
CGGTAACCCGTGTGACTTTGACTGGGTGGCTGAGATCTGCGTTGAAATGGAGCTGCGGGACGAGATTCTGCCCAGAGCCCAGAACATCCA
GAGCCGCCTGGACCGACAGACCATTGAGACAGAGGAGGTGAACAAGACTCTGAAGGCGACACTGCAGGCCCTGCTGGAGGTGGTGGCCTC
GGATGACGGGGATGTGCTTGATTCCTTCCAGACCAGCCCCTCCACCGAGTCCCTCAAGTCCACCAGCTCAGACCCAGGCAGCCGGCAGGC
GGGCCGGAGGCGCGGCCAGCAGCAGGAGACCGAAACCTTCTACCTCACGAAGCTCCAGGAGTATCTGAGTGGACGGAGCATCCTCGCCAA
GCTGCAGGCCAAGCACGAGAAGCTGCAGGAGGCCCTTCAGCGAGGTGACAAGGAGGAGCAGGAGGTGTCTTGGACCCAGTACACACAGAG
AAAATTCCAGAAGAGCCGCCAGCCCCGCCCCAGCTCCCAGTATAACCAGAGACTCTTTGGGGGAGACATGGAGAAGTTTATCCAGAGCTC
AGGCCAGCCTGTGCCCCTGGTGGTGGAGAGCTGCATTCGCTTCATCAACCTCAATGGCCTGCAGCATGAAGGCATCTTCCGGGTATCGGG
TGCCCAGCTCCGGGTCTCAGAGATCCGTGATGCCTTCGAGAGAGGGGAGGACCCACTGGTGGAGGGCTGCACTGCCCATGACCTGGACTC
GGTGGCCGGGGTGCTGAAGCTCTACTTCCGGAGCCTGGAGCCCCCACTCTTCCCCCCAGACCTGTTCGGCGAGCTGCTGGCTTCTTCGGA
GCTGGAGGCCACAGCGGAGAGGGTGGAGCACGTGAGCCGCCTGCTGTGGCGGCTGCCCGCGCCGGTGCTGGTGGTTCTGCGCTACCTCTT
CACCTTCCTCAACCACCTGGCCCAGTACAGCGATGAGAACATGATGGACCCCTACAACCTGGCCGTGTGCTTCGGGCCCACGCTGCTACC
GGTGCCCGCTGGGCAGGACCCGGTGGCGCTGCAGGGCCGGGTGAACCAGCTGGTGCAGACGCTCATAGTGCAGCCCGATCGGGTCTTCCC
GCCCCTGACCTCGCTGCCTGGCCCCGTCTACGAGAAGTGCATGGCACCGCCTTCCGCCAGCTGCCTGGGGGACGCCCAGCTGGAGAGCCT
GGGGGCGGACAATGAGCCGGAGCTGGAAGCCGAGATGCCCGCACAGGAGGATGACCTGGAGGGGGTCGTGGAGGCTGTGGCCTGCTTTGC
CTACACGGGCCGCACAGCCCAGGAGCTGAGCTTCCGGCGGGGGGACGTACTGCGGCTGCACGAGAGGGCCTCGAGCGACTGGTGGCGGGG
GGAGCACAACGGCATGCGGGGCCTCATCCCCCACAAGTATATCACGCTGCCCGCCGGGACGGAGAAGCAGGTGGTGGGCGCAGGGCTGCA
GACTGCAGGGGAGTCTGGGAGCAGTCCCGAGGGCCTCCTGGCATCGGAGCTGGTCCACCGGCCAGAGCCATGCACCTCACCTGAGGCCAT
GGGACCCTCTGGACACAGACGACGCTGCTTGGTCCCAGCCTCCCCAGAGCAACACGTGGAGGTGGATAAGGCTGTGGCACAGAACATGGA
CTCTGTGTTTAAGGAGCTCTTGGGAAAGACCTCTGTCCGCCAGGGCCTTGGGCCAGCATCTACCACCTCTCCCAGTCCTGGGCCCCGAAG
CCCAAAGGCCCCGCCCAGCAGCCGCCTGGGCAGGAACAAAGGCTTCTCCCGGGGCCCTGGGGCCCCAGCCTCACCCTCAGCTTCCCACCC
CCAGGGCCTAGACACGACCCCCAAGCCACACTGAGGTGCCGCTGCTGGAGATGCGTGCCCCCGGCGGCTACCCGCTGGACCGGCCACTCT
CCCCAGCCCCCTTGCTTCTCTCCAGCCCTGTCCAGCAAGTGCAGGGTGCCTGCACTTCACCCTGTGCAGAGAGGTGGGATGGGGCCGTGC
ACACAGGGATGCCCGCTCCACATCCTGCCTGCCCCTCAGCCCTGGCCCAGGCCCCTTTTGGAGGCAGCTGAGGAAGGATGCTGGGGAAAG
CCCTCTTCTGCAGCTTTGTGGAAGGCTGATCAGTGGCTGCTGGGTGGCGGGTACCCTTGCTCAGATGCCTGGCAGGGCTGGGTGGCGATT

>92556_92556_9_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000378312_ARHGAP4_chrX_153179333_ENST00000393721_length(amino acids)=665AA_BP=63
MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWVAEICVEMELRDEILPRAQNIQSRLDR
QTIETEEVNKTLKATLQALLEVVASDDGDVLDSFQTSPSTESLKSTSSDPGSRQAGRRRGQQQETETFYLTKLQEYLSGRSILAKLQAKH
EKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRV
SEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNH
LAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQPDRVFPPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNE
PELEAEMPAQEDDLEGVVEAVACFAYTGRTAQELSFRRGDVLRLHERASSDWWRGEHNGMRGLIPHKYITLPAGTEKQVVGAGLQTAGES
GSSPEGLLASELVHRPEPCTSPEAMGPSGHRRRCLVPASPEQHVEVDKAVAQNMDSVFKELLGKTSVRQGLGPASTTSPSPGPRSPKAPP

--------------------------------------------------------------
>92556_92556_10_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000378312_ARHGAP4_chrX_153179333_ENST00000537206_length(transcript)=2177nt_BP=205nt
CGTTACGGCCGAAAAGATGGCGGTCTTGGCACCTCTAATTGCTCTCGTGTATTCGGTGCCGCGACTTTCACGATGGCTCGCCCAACCTTA
CTACCTTCTGTCGGCCCTGCTCTCTGCTGCCTTCCTACTCGTGAGGAAACTGCCGCCGCTCTGCCACGGTCTGCCCACCCAACGCGAAGA
CGGTAACCCGTGTGACTTTGACTGGGTGGCTGAGATCTGCGTTGAAATGGAGCTGCGGGACGAGATTCTGCCCAGAGCCCAGAACATCCA
GAGCCGCCTGGACCGACAGACCATTGAGACAGAGGAGGTGAACAAGACTCTGAAGGCGACACTGCAGGCCCTGCTGGAGGTGGTGGCCTC
GGATGACGGGGATGTGCTTGATTCCTTCCAGACCAGCCCCTCCACCGAGTCCCTCAAGTCCACCAGCTCAGACCCAGGCAGCCGGCAGGC
GGGCCGGAGGCGCGGCCAGCAGCAGGAGACCGAAACCTTCTACCTCACGAAGCTCCAGGAGTATCTGAGTGGACGGAGCATCCTCGCCAA
GCTGCAGGCCAAGCACGAGAAGCTGCAGGAGGCCCTTCAGCGAGGTGACAAGGAGGAGCAGGAGGTGTCTTGGACCCAGTACACACAGAG
AAAATTCCAGAAGAGCCGCCAGCCCCGCCCCAGCTCCCAGTATAACCAGAGACTCTTTGGGGGAGACATGGAGAAGTTTATCCAGAGCTC
AGGCCAGCCTGTGCCCCTGGTGGTGGAGAGCTGCATTCGCTTCATCAACCTCAATGGCCTGCAGCATGAAGGCATCTTCCGGGTATCGGG
TGCCCAGCTCCGGGTCTCAGAGATCCGTGATGCCTTCGAGAGAGGGGAGGACCCACTGGTGGAGGGCTGCACTGCCCATGACCTGGACTC
GGTGGCCGGGGTGCTGAAGCTCTACTTCCGGAGCCTGGAGCCCCCACTCTTCCCCCCAGACCTGTTCGGCGAGCTGCTGGCTTCTTCGGA
GCTGGAGGCCACAGCGGAGAGGGTGGAGCACGTGAGCCGCCTGCTGTGGCGGCTGCCCGCGCCGGTGCTGGTGGTTCTGCGCTACCTCTT
CACCTTCCTCAACCACCTGGCCCAGTACAGCGATGAGAACATGATGGACCCCTACAACCTGGCCGTGTGCTTCGGGCCCACGCTGCTACC
GGTGCCCGCTGGGCAGGACCCGGTGGCGCTGCAGGGCCGGGTGAACCAGCTGGTGCAGACGCTCATAGTGCAGCCCGATCGGGTCTTCCC
GCCCCTGACCTCGCTGCCTGGCCCCGTCTACGAGAAGTGCATGGCACCGCCTTCCGCCAGCTGCCTGGGGGACGCCCAGCTGGAGAGCCT
GGGGGCGGACAATGAGCCGGAGCTGGAAGCCGAGATGCCCGCACAGGAGGATGACCTGGAGGGGGTCGTGGAGGCTGTGGCCTGCTTTGC
CTACACGGGCCGCACAGCCCAGGAGCTGAGCTTCCGGCGGGGGGACGTACTGCGGCTGCACGAGAGGGCCTCGAGCGACTGGTGGCGGGG
GGAGCACAACGGCATGCGGGGCCTCATCCCCCACAAGTATATCACGCTGCCCGCCGGGACGGAGAAGCAGGTGGTGGGCGCAGGGCTGCA
GACTGCAGGGGAGTCTGGGAGCAGTCCCGAGGGCCTCCTGGCATCGGAGCTGGTCCACCGGCCAGAGCCATGCACCTCACCTGAGGCCAT
GGGACCCTCTGGACACAGACGACGCTGCTTGGTCCCAGCCTCCCCAGAGCAACACGTGGAGGTGGATAAGGCTGTGGCACAGAACATGGA
CTCTGTGTTTAAGGAGCTCTTGGGAAAGACCTCTGTCCGCCAGGGCCTTGGGCCAGCATCTACCACCTCTCCCAGTCCTGGGCCCCGAAG
CCCAAAGGCCCCGCCCAGCAGCCGCCTGGGCAGGAACAAAGGCTTCTCCCGGGGCCCTGGGGCCCCAGCCTCACCCTCAGCTTCCCACCC
CCAGGGCCTAGACACGACCCCCAAGCCACACTGAGGTGCCGCTGCTGGAGATGCGTGCCCCCGGCGGCTACCCGCTGGACCGGCCACTCT
CCCCAGCCCCCTTGCTTCTCTCCAGCCCTGTCCAGCAAGTGCAGGGTGCCTGCACTTCACCCTGTGCAGAGAGGTGGGATGGGGCCGTGC

>92556_92556_10_TMX2-ARHGAP4_TMX2_chr11_57480279_ENST00000378312_ARHGAP4_chrX_153179333_ENST00000537206_length(amino acids)=665AA_BP=63
MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWVAEICVEMELRDEILPRAQNIQSRLDR
QTIETEEVNKTLKATLQALLEVVASDDGDVLDSFQTSPSTESLKSTSSDPGSRQAGRRRGQQQETETFYLTKLQEYLSGRSILAKLQAKH
EKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRV
SEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNH
LAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQPDRVFPPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNE
PELEAEMPAQEDDLEGVVEAVACFAYTGRTAQELSFRRGDVLRLHERASSDWWRGEHNGMRGLIPHKYITLPAGTEKQVVGAGLQTAGES
GSSPEGLLASELVHRPEPCTSPEAMGPSGHRRRCLVPASPEQHVEVDKAVAQNMDSVFKELLGKTSVRQGLGPASTTSPSPGPRSPKAPP

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for TMX2-ARHGAP4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for TMX2-ARHGAP4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for TMX2-ARHGAP4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource