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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TNFAIP1-EML1 (FusionGDB2 ID:92587)

Fusion Gene Summary for TNFAIP1-EML1

check button Fusion gene summary
Fusion gene informationFusion gene name: TNFAIP1-EML1
Fusion gene ID: 92587
HgeneTgene
Gene symbol

TNFAIP1

EML1

Gene ID

7126

2009

Gene nameTNF alpha induced protein 1EMAP like 1
SynonymsB12|B61|BTBD34|EDP1|hBACURD2BH|ELP79|EMAP|EMAP-1|EMAPL
Cytomap

17q11.2

14q32.2

Type of geneprotein-codingprotein-coding
DescriptionBTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2BTB/POZ domain-containing protein TNFAIP1tumor necrosis factor, alpha induced protein 1tumor necrosis factor, alpha-induced protein 1 (endothelial)echinoderm microtubule-associated protein-like 1echinoderm microtubule associated protein like 1
Modification date2020032720200313
UniProtAcc.

O00423

Ensembl transtripts involved in fusion geneENST00000226225, ENST00000544907, 
ENST00000583213, 		ENST00000556758, 
ENST00000262233, ENST00000327921, 
ENST00000334192, 
Fusion gene scores* DoF score6 X 6 X 3=1087 X 8 X 5=280
# samples 78
** MAII scorelog2(7/108*10)=-0.625604485218502
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/280*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TNFAIP1 [Title/Abstract] AND EML1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTNFAIP1(26667505)-EML1(100380614), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTNFAIP1

GO:0016567

protein ubiquitination

19782033

HgeneTNFAIP1

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

19782033


check buttonFusion gene breakpoints across TNFAIP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EML1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ABP356597TNFAIP1chr17

26667505

+EML1chr14

100380614

-


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Fusion Gene ORF analysis for TNFAIP1-EML1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000226225ENST00000556758TNFAIP1chr17

26667505

+EML1chr14

100380614

-
5CDS-intronENST00000544907ENST00000556758TNFAIP1chr17

26667505

+EML1chr14

100380614

-
In-frameENST00000226225ENST00000262233TNFAIP1chr17

26667505

+EML1chr14

100380614

-
In-frameENST00000226225ENST00000327921TNFAIP1chr17

26667505

+EML1chr14

100380614

-
In-frameENST00000226225ENST00000334192TNFAIP1chr17

26667505

+EML1chr14

100380614

-
In-frameENST00000544907ENST00000262233TNFAIP1chr17

26667505

+EML1chr14

100380614

-
In-frameENST00000544907ENST00000327921TNFAIP1chr17

26667505

+EML1chr14

100380614

-
In-frameENST00000544907ENST00000334192TNFAIP1chr17

26667505

+EML1chr14

100380614

-
intron-3CDSENST00000583213ENST00000262233TNFAIP1chr17

26667505

+EML1chr14

100380614

-
intron-3CDSENST00000583213ENST00000327921TNFAIP1chr17

26667505

+EML1chr14

100380614

-
intron-3CDSENST00000583213ENST00000334192TNFAIP1chr17

26667505

+EML1chr14

100380614

-
intron-intronENST00000583213ENST00000556758TNFAIP1chr17

26667505

+EML1chr14

100380614

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000544907TNFAIP1chr1726667505+ENST00000327921EML1chr14100380614-14924251641279371
ENST00000544907TNFAIP1chr1726667505+ENST00000262233EML1chr14100380614-32284251641279371
ENST00000544907TNFAIP1chr1726667505+ENST00000334192EML1chr14100380614-27054251641279371
ENST00000226225TNFAIP1chr1726667505+ENST00000327921EML1chr14100380614-17096421711496441
ENST00000226225TNFAIP1chr1726667505+ENST00000262233EML1chr14100380614-34456421711496441
ENST00000226225TNFAIP1chr1726667505+ENST00000334192EML1chr14100380614-29226421711496441

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000544907ENST00000327921TNFAIP1chr1726667505+EML1chr14100380614-0.003047860.9969522
ENST00000544907ENST00000262233TNFAIP1chr1726667505+EML1chr14100380614-0.0007705490.99922943
ENST00000544907ENST00000334192TNFAIP1chr1726667505+EML1chr14100380614-0.0011572030.9988427
ENST00000226225ENST00000327921TNFAIP1chr1726667505+EML1chr14100380614-0.0061077490.9938923
ENST00000226225ENST00000262233TNFAIP1chr1726667505+EML1chr14100380614-0.0016694590.99833053
ENST00000226225ENST00000334192TNFAIP1chr1726667505+EML1chr14100380614-0.0023412340.9976587

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Fusion Genomic Features for TNFAIP1-EML1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TNFAIP1-EML1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:26667505/chr14:100380614)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EML1

O00423

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division. Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain development. Does not affect neuron migration per se. {ECO:0000250|UniProtKB:Q05BC3}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTNFAIP1chr17:26667505chr14:100380614ENST00000226225+3728_96125317.0DomainBTB
TgeneEML1chr17:26667505chr14:100380614ENST00000262233022160_1660816.0Compositional biasNote=Poly-Ser
TgeneEML1chr17:26667505chr14:100380614ENST00000334192023160_1660835.0Compositional biasNote=Poly-Ser
TgeneEML1chr17:26667505chr14:100380614ENST00000262233022176_8150816.0RegionNote=Tandem atypical propeller in EMLs
TgeneEML1chr17:26667505chr14:100380614ENST00000334192023176_8150835.0RegionNote=Tandem atypical propeller in EMLs
TgeneEML1chr17:26667505chr14:100380614ENST00000262233022261_3100816.0RepeatNote=WD 1
TgeneEML1chr17:26667505chr14:100380614ENST00000262233022315_3580816.0RepeatNote=WD 2
TgeneEML1chr17:26667505chr14:100380614ENST00000262233022363_4000816.0RepeatNote=WD 3
TgeneEML1chr17:26667505chr14:100380614ENST00000262233022409_4460816.0RepeatNote=WD 4
TgeneEML1chr17:26667505chr14:100380614ENST00000262233022450_4890816.0RepeatNote=WD 5
TgeneEML1chr17:26667505chr14:100380614ENST00000262233022493_5300816.0RepeatNote=WD 6
TgeneEML1chr17:26667505chr14:100380614ENST00000262233022535_5720816.0RepeatNote=WD 7
TgeneEML1chr17:26667505chr14:100380614ENST00000262233022578_6130816.0RepeatNote=WD 8
TgeneEML1chr17:26667505chr14:100380614ENST00000262233022617_6550816.0RepeatNote=WD 9
TgeneEML1chr17:26667505chr14:100380614ENST00000262233022664_7010816.0RepeatNote=WD 10
TgeneEML1chr17:26667505chr14:100380614ENST00000262233022709_7680816.0RepeatNote=WD 11
TgeneEML1chr17:26667505chr14:100380614ENST00000262233022775_8140816.0RepeatNote=WD 12
TgeneEML1chr17:26667505chr14:100380614ENST00000334192023261_3100835.0RepeatNote=WD 1
TgeneEML1chr17:26667505chr14:100380614ENST00000334192023315_3580835.0RepeatNote=WD 2
TgeneEML1chr17:26667505chr14:100380614ENST00000334192023363_4000835.0RepeatNote=WD 3
TgeneEML1chr17:26667505chr14:100380614ENST00000334192023409_4460835.0RepeatNote=WD 4
TgeneEML1chr17:26667505chr14:100380614ENST00000334192023450_4890835.0RepeatNote=WD 5
TgeneEML1chr17:26667505chr14:100380614ENST00000334192023493_5300835.0RepeatNote=WD 6
TgeneEML1chr17:26667505chr14:100380614ENST00000334192023535_5720835.0RepeatNote=WD 7
TgeneEML1chr17:26667505chr14:100380614ENST00000334192023578_6130835.0RepeatNote=WD 8
TgeneEML1chr17:26667505chr14:100380614ENST00000334192023617_6550835.0RepeatNote=WD 9
TgeneEML1chr17:26667505chr14:100380614ENST00000334192023664_7010835.0RepeatNote=WD 10
TgeneEML1chr17:26667505chr14:100380614ENST00000334192023709_7680835.0RepeatNote=WD 11
TgeneEML1chr17:26667505chr14:100380614ENST00000334192023775_8140835.0RepeatNote=WD 12

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for TNFAIP1-EML1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>92587_92587_1_TNFAIP1-EML1_TNFAIP1_chr17_26667505_ENST00000226225_EML1_chr14_100380614_ENST00000262233_length(transcript)=3445nt_BP=642nt
AGCCGGCTGGGCTGGGCAGCACTCCGGGCGGAGTCGACGAGCGCAGGATGTGAGCTCACAGCTTGGGACTGCTGAGGGGCAGGCGGCTGC
AGGCTAGGGGCGGCTCGGAGTCCGCTGGCCACCCAGCTGAGAGGAGAGGCGCCCCCGGGGACGCACTGAGATTATGAGGCTCTGGCCTCC
ACTGGCCACTCACTCGTGACCCTTTCCACCACGGCGGAGCCTTCCAAGCCTACCTCCTGCCGTGTGGTGATCTACCTGCAGCGGGAGATG
TCGGGGGACACCTGCCTGTGCCCAGCCTCAGGGGCCAAGCCCAAGCTCAGTGGCTTCAAGGGAGGAGGGTTGGGCAACAAGTATGTCCAG
CTCAACGTGGGCGGCTCTCTGTACTACACCACTGTGCGGGCCCTGACCCGCCACGACACCATGCTCAAGGCCATGTTCAGTGGGCGCATG
GAGGTGCTGACCGACAAAGAAGGCTGGATCCTCATAGACCGTTGTGGAAAGCACTTTGGCACCATTTTGAATTACCTCCGAGATGACACC
ATCACCCTCCCTCAGAACCGGCAAGAAATCAAGGAATTGATGGCTGAAGCAAAGTATTACCTCATCCAGGGGCTGGTGAATATGTGCCAG
AGTGCCCTGCAGTCAGGGGACTTCACACCCATTACTCAGGGTCACACTGATGAGCTCTGGGGACTGGCCATCCATGCCTCAAAATCTCAG
TTCTTGACCTGTGGGCATGACAAGCATGCCACTCTCTGGGACGCTGTGGGTCACCGTCCCGTCTGGGACAAAATAATAGAGGATCCAGCT
CAGTCTTCTGGTTTTCATCCTTCAGGGTCTGTGGTTGCAGTCGGAACACTCACTGGGAGGTGGTTTGTGTTTGACACAGAAACAAAAGAC
TTGGTCACCGTTCACACAGATGGAAACGAACAGCTCTCTGTAATGCGATACTCACCAGATGGGAATTTCTTAGCCATAGGCTCACATGAC
AACTGCATCTATATATATGGCGTTAGTGACAACGGGAGGAAGTACACGCGAGTGGGCAAGTGCTCGGGTCATTCCAGCTTCATTACTCAC
CTGGACTGGTCTGTAAACTCACAGTTCCTCGTGTCAAATTCCGGAGACTACGAAATCCTCTACTGGGTTCCCTCTGCCTGTAAGCAAGTC
GTAAGTGTGGAAACTACAAGAGACATTGAATGGGCTACCTATACCTGCACTTTGGGATTCCATGTTTTTGGAGTGTGGCCAGAAGGCTCG
GACGGAACCGACATCAATGCCGTCTGTCGGGCCCATGAGAAGAAACTCCTGTCAACAGGCGACGACTTTGGCAAAGTGCACCTCTTCTCA
TACCCCTGCTCGCAGTTCAGGGCTCCAAGCCACATCTACGGCGGGCACAGCAGCCATGTCACCAATGTCGATTTCCTCTGTGAAGACAGC
CACCTCATCTCCACGGGCGGGAAAGACACAAGCATCATGCAGTGGCGCGTCATTTAGTACCCACCGAGAGCTGTGGGGAGCAGCATGGGC
AAGGAAGACACAGACTCGCATTACCCTTGGTCACTGTGATTTCTGTTTTGTTTAAAAAATTCTTACAAACCTCAGGAAAACTGTGCCCTC
CGCCGGCTACCTTAGCTTAGCGTGTCAGCGGGCGCCACAGCGGATCAGCGGTTCCGTGTTCACTTTTGTTGTACAATATATGACACAGTG
CACATTGAATACCAACAAGGTTGCAACGTTTACATTATAGCCACATCAACAGAAGTAACTGGTATATTCTTAGTAACTTTTCTATGAACT
CTTCAAAAATGGTCACAGAATGCCTTTTAAAACATTGTATATAATCTTCACTGTTTCACCATCTAGCTTGCTAAGTCAAATATTTATGAT
GATAATGAGGTACTGAACCACGATGGCTGTTGAGGAATTGGTCCTAAAAGGACAGATCACTTCAGAAGAGTGAATAACTGATTTGCACAG
CTGAATCAGGAGACACAAAGATGAGACTGTGTTTGGTTACATTTTCCAAAGTTTCATTGCATTCTCCCTTGGGGAGGCTGTGAGAGAGGG
CTTGTATCCCTCTTGTGCTAAGCAGACTCTACTCCTAACTGACTTCAATATTTCAGCAGGGTACACAGGCGTTTCCAAGTTTCAGTGACA
CCGTCCTGCCTAACCAGATGCGGTCAGCCTCTTCACACCCACCTGGCTTGCATCCCCCATCCCTTGTTCACACGCCCTGATTCACGGTGA
GACATTTTGCCACCTTCTTGTGTATATTACTTGGCATGAGATGATATTGTACTTGTATAGGATTCTAGCAATTCATAATAAATATGTAAG
ACTAGGCTTTACTGTCTTATGCTTATGGACATTGTATATTTGTATTTTATGACCAAGTAGACCAAGTCAGAAAGATCTCTCTCGAGCGTA
CCATAAACCTGCAGAGAGAAGTCTCGAAAGGCTCCACCAGGTACCAAGGGCAGCTGCTTTTCCTGTCTTTTGTGCATGGGCGACCCATTA
CAGTATGAGATAAGATTGAGTTCTGATGCGTTAAACGGAGGTGGCAGAAATTTGTCAAGAAGGCCTTATCCATTTCGATTGTGTGACAGA
TTGAAATTTATTGTTTACATTGGGGAATGTATCTCAAATTTTTAAATAGAAGAGTAATAAACAGACTTTAAAGCAAATATTAAGATTTTT
ACTCATTCAAGGCAAGTAAATGAATGGAATTATCTGAGCTCTATGGCACTGGTTGTTTAGAGTGACTGATGAAGTGCAACTTTCAAAAAC
ATTTTTGATGACATCACCAGCCTACTGCAGAAGTGCAGGGCACCAGTAAACACCATGTATTATTGAAGATGAATCTGTTTGTATGTATCC
TTGTCAAATATATTCTATAATGAAATAAAATCTGAAAAGTGGATTTCTTATTGACCTATATTCATGAAAGCATATAAATTAAAATATTTA
AAATTAGATATGATTCACACTATATTCTGTTTCATATGCAGATTTTATTCTCACCTGGGCCATTTGCAGATGAGACTGTAGTTTGCAGAT
GAGACTGTAGTTTGCAGATGGCGTGGAAGCATTCATCAGGGGAGATAACCATAAAGGATTTGGCCTAATTACCATACTCAATTGTCAGTT
TACGTGGTTTTGTGAATACTGGCAAAAGCAATTGTTTTTAAATTAACAATGGAGAGAATGATAAGATGAGGGAAGGAAAAGGCATTCATT
ATTGACTTACATGTCAGTAAGGTCTGCTTTTATTTCTATGTACTCCTGTTTGCCAAGCTCAATAATGGACAAAGGATACAAACACACACA
CATCTACTATTTTAGATAAATGTACTGTTATATATATATGTAAACTACTATTGCTCTCTTTATAATGATTAATCACTTTATTATGAATGA

>92587_92587_1_TNFAIP1-EML1_TNFAIP1_chr17_26667505_ENST00000226225_EML1_chr14_100380614_ENST00000262233_length(amino acids)=441AA_BP=157
MASTGHSLVTLSTTAEPSKPTSCRVVIYLQREMSGDTCLCPASGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFS
GRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQSGDFTPITQGHTDELWGLAIHAS
KSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIG
SHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTRDIEWATYTCTLGFHVFGVWP

--------------------------------------------------------------
>92587_92587_2_TNFAIP1-EML1_TNFAIP1_chr17_26667505_ENST00000226225_EML1_chr14_100380614_ENST00000327921_length(transcript)=1709nt_BP=642nt
AGCCGGCTGGGCTGGGCAGCACTCCGGGCGGAGTCGACGAGCGCAGGATGTGAGCTCACAGCTTGGGACTGCTGAGGGGCAGGCGGCTGC
AGGCTAGGGGCGGCTCGGAGTCCGCTGGCCACCCAGCTGAGAGGAGAGGCGCCCCCGGGGACGCACTGAGATTATGAGGCTCTGGCCTCC
ACTGGCCACTCACTCGTGACCCTTTCCACCACGGCGGAGCCTTCCAAGCCTACCTCCTGCCGTGTGGTGATCTACCTGCAGCGGGAGATG
TCGGGGGACACCTGCCTGTGCCCAGCCTCAGGGGCCAAGCCCAAGCTCAGTGGCTTCAAGGGAGGAGGGTTGGGCAACAAGTATGTCCAG
CTCAACGTGGGCGGCTCTCTGTACTACACCACTGTGCGGGCCCTGACCCGCCACGACACCATGCTCAAGGCCATGTTCAGTGGGCGCATG
GAGGTGCTGACCGACAAAGAAGGCTGGATCCTCATAGACCGTTGTGGAAAGCACTTTGGCACCATTTTGAATTACCTCCGAGATGACACC
ATCACCCTCCCTCAGAACCGGCAAGAAATCAAGGAATTGATGGCTGAAGCAAAGTATTACCTCATCCAGGGGCTGGTGAATATGTGCCAG
AGTGCCCTGCAGTCAGGGGACTTCACACCCATTACTCAGGGTCACACTGATGAGCTCTGGGGACTGGCCATCCATGCCTCAAAATCTCAG
TTCTTGACCTGTGGGCATGACAAGCATGCCACTCTCTGGGACGCTGTGGGTCACCGTCCCGTCTGGGACAAAATAATAGAGGATCCAGCT
CAGTCTTCTGGTTTTCATCCTTCAGGGTCTGTGGTTGCAGTCGGAACACTCACTGGGAGGTGGTTTGTGTTTGACACAGAAACAAAAGAC
TTGGTCACCGTTCACACAGATGGAAACGAACAGCTCTCTGTAATGCGATACTCACCAGATGGGAATTTCTTAGCCATAGGCTCACATGAC
AACTGCATCTATATATATGGCGTTAGTGACAACGGGAGGAAGTACACGCGAGTGGGCAAGTGCTCGGGTCATTCCAGCTTCATTACTCAC
CTGGACTGGTCTGTAAACTCACAGTTCCTCGTGTCAAATTCCGGAGACTACGAAATCCTCTACTGGGTTCCCTCTGCCTGTAAGCAAGTC
GTAAGTGTGGAAACTACAAGAGACATTGAATGGGCTACCTATACCTGCACTTTGGGATTCCATGTTTTTGGAGTGTGGCCAGAAGGCTCG
GACGGAACCGACATCAATGCCGTCTGTCGGGCCCATGAGAAGAAACTCCTGTCAACAGGCGACGACTTTGGCAAAGTGCACCTCTTCTCA
TACCCCTGCTCGCAGTTCAGGGCTCCAAGCCACATCTACGGCGGGCACAGCAGCCATGTCACCAATGTCGATTTCCTCTGTGAAGACAGC
CACCTCATCTCCACGGGCGGGAAAGACACAAGCATCATGCAGTGGCGCGTCATTTAGTACCCACCGAGAGCTGTGGGGAGCAGCATGGGC
AAGGAAGACACAGACTCGCATTACCCTTGGTCACTGTGATTTCTGTTTTGTTTAAAAAATTCTTACAAACCTCAGGAAAACTGTGCCCTC

>92587_92587_2_TNFAIP1-EML1_TNFAIP1_chr17_26667505_ENST00000226225_EML1_chr14_100380614_ENST00000327921_length(amino acids)=441AA_BP=157
MASTGHSLVTLSTTAEPSKPTSCRVVIYLQREMSGDTCLCPASGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFS
GRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQSGDFTPITQGHTDELWGLAIHAS
KSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIG
SHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTRDIEWATYTCTLGFHVFGVWP

--------------------------------------------------------------
>92587_92587_3_TNFAIP1-EML1_TNFAIP1_chr17_26667505_ENST00000226225_EML1_chr14_100380614_ENST00000334192_length(transcript)=2922nt_BP=642nt
AGCCGGCTGGGCTGGGCAGCACTCCGGGCGGAGTCGACGAGCGCAGGATGTGAGCTCACAGCTTGGGACTGCTGAGGGGCAGGCGGCTGC
AGGCTAGGGGCGGCTCGGAGTCCGCTGGCCACCCAGCTGAGAGGAGAGGCGCCCCCGGGGACGCACTGAGATTATGAGGCTCTGGCCTCC
ACTGGCCACTCACTCGTGACCCTTTCCACCACGGCGGAGCCTTCCAAGCCTACCTCCTGCCGTGTGGTGATCTACCTGCAGCGGGAGATG
TCGGGGGACACCTGCCTGTGCCCAGCCTCAGGGGCCAAGCCCAAGCTCAGTGGCTTCAAGGGAGGAGGGTTGGGCAACAAGTATGTCCAG
CTCAACGTGGGCGGCTCTCTGTACTACACCACTGTGCGGGCCCTGACCCGCCACGACACCATGCTCAAGGCCATGTTCAGTGGGCGCATG
GAGGTGCTGACCGACAAAGAAGGCTGGATCCTCATAGACCGTTGTGGAAAGCACTTTGGCACCATTTTGAATTACCTCCGAGATGACACC
ATCACCCTCCCTCAGAACCGGCAAGAAATCAAGGAATTGATGGCTGAAGCAAAGTATTACCTCATCCAGGGGCTGGTGAATATGTGCCAG
AGTGCCCTGCAGTCAGGGGACTTCACACCCATTACTCAGGGTCACACTGATGAGCTCTGGGGACTGGCCATCCATGCCTCAAAATCTCAG
TTCTTGACCTGTGGGCATGACAAGCATGCCACTCTCTGGGACGCTGTGGGTCACCGTCCCGTCTGGGACAAAATAATAGAGGATCCAGCT
CAGTCTTCTGGTTTTCATCCTTCAGGGTCTGTGGTTGCAGTCGGAACACTCACTGGGAGGTGGTTTGTGTTTGACACAGAAACAAAAGAC
TTGGTCACCGTTCACACAGATGGAAACGAACAGCTCTCTGTAATGCGATACTCACCAGATGGGAATTTCTTAGCCATAGGCTCACATGAC
AACTGCATCTATATATATGGCGTTAGTGACAACGGGAGGAAGTACACGCGAGTGGGCAAGTGCTCGGGTCATTCCAGCTTCATTACTCAC
CTGGACTGGTCTGTAAACTCACAGTTCCTCGTGTCAAATTCCGGAGACTACGAAATCCTCTACTGGGTTCCCTCTGCCTGTAAGCAAGTC
GTAAGTGTGGAAACTACAAGAGACATTGAATGGGCTACCTATACCTGCACTTTGGGATTCCATGTTTTTGGAGTGTGGCCAGAAGGCTCG
GACGGAACCGACATCAATGCCGTCTGTCGGGCCCATGAGAAGAAACTCCTGTCAACAGGCGACGACTTTGGCAAAGTGCACCTCTTCTCA
TACCCCTGCTCGCAGTTCAGGGCTCCAAGCCACATCTACGGCGGGCACAGCAGCCATGTCACCAATGTCGATTTCCTCTGTGAAGACAGC
CACCTCATCTCCACGGGCGGGAAAGACACAAGCATCATGCAGTGGCGCGTCATTTAGTACCCACCGAGAGCTGTGGGGAGCAGCATGGGC
AAGGAAGACACAGACTCGCATTACCCTTGGTCACTGTGATTTCTGTTTTGTTTAAAAAATTCTTACAAACCTCAGGAAAACTGTGCCCTC
CGCCGGCTACCTTAGCTTAGCGTGTCAGCGGGCGCCACAGCGGATCAGCGGTTCCGTGTTCACTTTTGTTGTACAATATATGACACAGTG
CACATTGAATACCAACAAGGTTGCAACGTTTACATTATAGCCACATCAACAGAAGTAACTGGTATATTCTTAGTAACTTTTCTATGAACT
CTTCAAAAATGGTCACAGAATGCCTTTTAAAACATTGTATATAATCTTCACTGTTTCACCATCTAGCTTGCTAAGTCAAATATTTATGAT
GATAATGAGGTACTGAACCACGATGGCTGTTGAGGAATTGGTCCTAAAAGGACAGATCACTTCAGAAGAGTGAATAACTGATTTGCACAG
CTGAATCAGGAGACACAAAGATGAGACTGTGTTTGGTTACATTTTCCAAAGTTTCATTGCATTCTCCCTTGGGGAGGCTGTGAGAGAGGG
CTTGTATCCCTCTTGTGCTAAGCAGACTCTACTCCTAACTGACTTCAATATTTCAGCAGGGTACACAGGCGTTTCCAAGTTTCAGTGACA
CCGTCCTGCCTAACCAGATGCGGTCAGCCTCTTCACACCCACCTGGCTTGCATCCCCCATCCCTTGTTCACACGCCCTGATTCACGGTGA
GACATTTTGCCACCTTCTTGTGTATATTACTTGGCATGAGATGATATTGTACTTGTATAGGATTCTAGCAATTCATAATAAATATGTAAG
ACTAGGCTTTACTGTCTTATGCTTATGGACATTGTATATTTGTATTTTATGACCAAGTAGACCAAGTCAGAAAGATCTCTCTCGAGCGTA
CCATAAACCTGCAGAGAGAAGTCTCGAAAGGCTCCACCAGGTACCAAGGGCAGCTGCTTTTCCTGTCTTTTGTGCATGGGCGACCCATTA
CAGTATGAGATAAGATTGAGTTCTGATGCGTTAAACGGAGGTGGCAGAAATTTGTCAAGAAGGCCTTATCCATTTCGATTGTGTGACAGA
TTGAAATTTATTGTTTACATTGGGGAATGTATCTCAAATTTTTAAATAGAAGAGTAATAAACAGACTTTAAAGCAAATATTAAGATTTTT
ACTCATTCAAGGCAAGTAAATGAATGGAATTATCTGAGCTCTATGGCACTGGTTGTTTAGAGTGACTGATGAAGTGCAACTTTCAAAAAC
ATTTTTGATGACATCACCAGCCTACTGCAGAAGTGCAGGGCACCAGTAAACACCATGTATTATTGAAGATGAATCTGTTTGTATGTATCC

>92587_92587_3_TNFAIP1-EML1_TNFAIP1_chr17_26667505_ENST00000226225_EML1_chr14_100380614_ENST00000334192_length(amino acids)=441AA_BP=157
MASTGHSLVTLSTTAEPSKPTSCRVVIYLQREMSGDTCLCPASGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFS
GRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQSGDFTPITQGHTDELWGLAIHAS
KSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIG
SHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTRDIEWATYTCTLGFHVFGVWP

--------------------------------------------------------------
>92587_92587_4_TNFAIP1-EML1_TNFAIP1_chr17_26667505_ENST00000544907_EML1_chr14_100380614_ENST00000262233_length(transcript)=3228nt_BP=425nt
AAGTAGCTCTGCTCTCTCCGCGAAGACCCTCGGGGGATTCCGCCTCCACCCTTTCCCGGATAGAGCGCTATGCATGCAGGGACTTGTAGT
CTCAGGCTCCCCAGCCGGCTGGGCTGGGCAGCACTCCGGGCGGAGTCGACGAGCGCAGGATGTGAGCTCACAGCTTGGGACTGCTGAGGG
GCAGGCGGCTGCAGGCTAGGGGCGGCTCGGAGTCCGCTGGCCACCCAGCTGAGAGGAGAGGCGCCCCCGGGGACGGCTGGATCCTCATAG
ACCGTTGTGGAAAGCACTTTGGCACCATTTTGAATTACCTCCGAGATGACACCATCACCCTCCCTCAGAACCGGCAAGAAATCAAGGAAT
TGATGGCTGAAGCAAAGTATTACCTCATCCAGGGGCTGGTGAATATGTGCCAGAGTGCCCTGCAGTCAGGGGACTTCACACCCATTACTC
AGGGTCACACTGATGAGCTCTGGGGACTGGCCATCCATGCCTCAAAATCTCAGTTCTTGACCTGTGGGCATGACAAGCATGCCACTCTCT
GGGACGCTGTGGGTCACCGTCCCGTCTGGGACAAAATAATAGAGGATCCAGCTCAGTCTTCTGGTTTTCATCCTTCAGGGTCTGTGGTTG
CAGTCGGAACACTCACTGGGAGGTGGTTTGTGTTTGACACAGAAACAAAAGACTTGGTCACCGTTCACACAGATGGAAACGAACAGCTCT
CTGTAATGCGATACTCACCAGATGGGAATTTCTTAGCCATAGGCTCACATGACAACTGCATCTATATATATGGCGTTAGTGACAACGGGA
GGAAGTACACGCGAGTGGGCAAGTGCTCGGGTCATTCCAGCTTCATTACTCACCTGGACTGGTCTGTAAACTCACAGTTCCTCGTGTCAA
ATTCCGGAGACTACGAAATCCTCTACTGGGTTCCCTCTGCCTGTAAGCAAGTCGTAAGTGTGGAAACTACAAGAGACATTGAATGGGCTA
CCTATACCTGCACTTTGGGATTCCATGTTTTTGGAGTGTGGCCAGAAGGCTCGGACGGAACCGACATCAATGCCGTCTGTCGGGCCCATG
AGAAGAAACTCCTGTCAACAGGCGACGACTTTGGCAAAGTGCACCTCTTCTCATACCCCTGCTCGCAGTTCAGGGCTCCAAGCCACATCT
ACGGCGGGCACAGCAGCCATGTCACCAATGTCGATTTCCTCTGTGAAGACAGCCACCTCATCTCCACGGGCGGGAAAGACACAAGCATCA
TGCAGTGGCGCGTCATTTAGTACCCACCGAGAGCTGTGGGGAGCAGCATGGGCAAGGAAGACACAGACTCGCATTACCCTTGGTCACTGT
GATTTCTGTTTTGTTTAAAAAATTCTTACAAACCTCAGGAAAACTGTGCCCTCCGCCGGCTACCTTAGCTTAGCGTGTCAGCGGGCGCCA
CAGCGGATCAGCGGTTCCGTGTTCACTTTTGTTGTACAATATATGACACAGTGCACATTGAATACCAACAAGGTTGCAACGTTTACATTA
TAGCCACATCAACAGAAGTAACTGGTATATTCTTAGTAACTTTTCTATGAACTCTTCAAAAATGGTCACAGAATGCCTTTTAAAACATTG
TATATAATCTTCACTGTTTCACCATCTAGCTTGCTAAGTCAAATATTTATGATGATAATGAGGTACTGAACCACGATGGCTGTTGAGGAA
TTGGTCCTAAAAGGACAGATCACTTCAGAAGAGTGAATAACTGATTTGCACAGCTGAATCAGGAGACACAAAGATGAGACTGTGTTTGGT
TACATTTTCCAAAGTTTCATTGCATTCTCCCTTGGGGAGGCTGTGAGAGAGGGCTTGTATCCCTCTTGTGCTAAGCAGACTCTACTCCTA
ACTGACTTCAATATTTCAGCAGGGTACACAGGCGTTTCCAAGTTTCAGTGACACCGTCCTGCCTAACCAGATGCGGTCAGCCTCTTCACA
CCCACCTGGCTTGCATCCCCCATCCCTTGTTCACACGCCCTGATTCACGGTGAGACATTTTGCCACCTTCTTGTGTATATTACTTGGCAT
GAGATGATATTGTACTTGTATAGGATTCTAGCAATTCATAATAAATATGTAAGACTAGGCTTTACTGTCTTATGCTTATGGACATTGTAT
ATTTGTATTTTATGACCAAGTAGACCAAGTCAGAAAGATCTCTCTCGAGCGTACCATAAACCTGCAGAGAGAAGTCTCGAAAGGCTCCAC
CAGGTACCAAGGGCAGCTGCTTTTCCTGTCTTTTGTGCATGGGCGACCCATTACAGTATGAGATAAGATTGAGTTCTGATGCGTTAAACG
GAGGTGGCAGAAATTTGTCAAGAAGGCCTTATCCATTTCGATTGTGTGACAGATTGAAATTTATTGTTTACATTGGGGAATGTATCTCAA
ATTTTTAAATAGAAGAGTAATAAACAGACTTTAAAGCAAATATTAAGATTTTTACTCATTCAAGGCAAGTAAATGAATGGAATTATCTGA
GCTCTATGGCACTGGTTGTTTAGAGTGACTGATGAAGTGCAACTTTCAAAAACATTTTTGATGACATCACCAGCCTACTGCAGAAGTGCA
GGGCACCAGTAAACACCATGTATTATTGAAGATGAATCTGTTTGTATGTATCCTTGTCAAATATATTCTATAATGAAATAAAATCTGAAA
AGTGGATTTCTTATTGACCTATATTCATGAAAGCATATAAATTAAAATATTTAAAATTAGATATGATTCACACTATATTCTGTTTCATAT
GCAGATTTTATTCTCACCTGGGCCATTTGCAGATGAGACTGTAGTTTGCAGATGAGACTGTAGTTTGCAGATGGCGTGGAAGCATTCATC
AGGGGAGATAACCATAAAGGATTTGGCCTAATTACCATACTCAATTGTCAGTTTACGTGGTTTTGTGAATACTGGCAAAAGCAATTGTTT
TTAAATTAACAATGGAGAGAATGATAAGATGAGGGAAGGAAAAGGCATTCATTATTGACTTACATGTCAGTAAGGTCTGCTTTTATTTCT
ATGTACTCCTGTTTGCCAAGCTCAATAATGGACAAAGGATACAAACACACACACATCTACTATTTTAGATAAATGTACTGTTATATATAT

>92587_92587_4_TNFAIP1-EML1_TNFAIP1_chr17_26667505_ENST00000544907_EML1_chr14_100380614_ENST00000262233_length(amino acids)=371AA_BP=87
MGLLRGRRLQARGGSESAGHPAERRGAPGDGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQSGD
FTPITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTD
GNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTR
DIEWATYTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAPSHIYGGHSSHVTNVDFLCEDSHLISTGG

--------------------------------------------------------------
>92587_92587_5_TNFAIP1-EML1_TNFAIP1_chr17_26667505_ENST00000544907_EML1_chr14_100380614_ENST00000327921_length(transcript)=1492nt_BP=425nt
AAGTAGCTCTGCTCTCTCCGCGAAGACCCTCGGGGGATTCCGCCTCCACCCTTTCCCGGATAGAGCGCTATGCATGCAGGGACTTGTAGT
CTCAGGCTCCCCAGCCGGCTGGGCTGGGCAGCACTCCGGGCGGAGTCGACGAGCGCAGGATGTGAGCTCACAGCTTGGGACTGCTGAGGG
GCAGGCGGCTGCAGGCTAGGGGCGGCTCGGAGTCCGCTGGCCACCCAGCTGAGAGGAGAGGCGCCCCCGGGGACGGCTGGATCCTCATAG
ACCGTTGTGGAAAGCACTTTGGCACCATTTTGAATTACCTCCGAGATGACACCATCACCCTCCCTCAGAACCGGCAAGAAATCAAGGAAT
TGATGGCTGAAGCAAAGTATTACCTCATCCAGGGGCTGGTGAATATGTGCCAGAGTGCCCTGCAGTCAGGGGACTTCACACCCATTACTC
AGGGTCACACTGATGAGCTCTGGGGACTGGCCATCCATGCCTCAAAATCTCAGTTCTTGACCTGTGGGCATGACAAGCATGCCACTCTCT
GGGACGCTGTGGGTCACCGTCCCGTCTGGGACAAAATAATAGAGGATCCAGCTCAGTCTTCTGGTTTTCATCCTTCAGGGTCTGTGGTTG
CAGTCGGAACACTCACTGGGAGGTGGTTTGTGTTTGACACAGAAACAAAAGACTTGGTCACCGTTCACACAGATGGAAACGAACAGCTCT
CTGTAATGCGATACTCACCAGATGGGAATTTCTTAGCCATAGGCTCACATGACAACTGCATCTATATATATGGCGTTAGTGACAACGGGA
GGAAGTACACGCGAGTGGGCAAGTGCTCGGGTCATTCCAGCTTCATTACTCACCTGGACTGGTCTGTAAACTCACAGTTCCTCGTGTCAA
ATTCCGGAGACTACGAAATCCTCTACTGGGTTCCCTCTGCCTGTAAGCAAGTCGTAAGTGTGGAAACTACAAGAGACATTGAATGGGCTA
CCTATACCTGCACTTTGGGATTCCATGTTTTTGGAGTGTGGCCAGAAGGCTCGGACGGAACCGACATCAATGCCGTCTGTCGGGCCCATG
AGAAGAAACTCCTGTCAACAGGCGACGACTTTGGCAAAGTGCACCTCTTCTCATACCCCTGCTCGCAGTTCAGGGCTCCAAGCCACATCT
ACGGCGGGCACAGCAGCCATGTCACCAATGTCGATTTCCTCTGTGAAGACAGCCACCTCATCTCCACGGGCGGGAAAGACACAAGCATCA
TGCAGTGGCGCGTCATTTAGTACCCACCGAGAGCTGTGGGGAGCAGCATGGGCAAGGAAGACACAGACTCGCATTACCCTTGGTCACTGT
GATTTCTGTTTTGTTTAAAAAATTCTTACAAACCTCAGGAAAACTGTGCCCTCCGCCGGCTACCTTAGCTTAGCGTGTCAGCGGGCGCCA

>92587_92587_5_TNFAIP1-EML1_TNFAIP1_chr17_26667505_ENST00000544907_EML1_chr14_100380614_ENST00000327921_length(amino acids)=371AA_BP=87
MGLLRGRRLQARGGSESAGHPAERRGAPGDGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQSGD
FTPITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTD
GNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTR
DIEWATYTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAPSHIYGGHSSHVTNVDFLCEDSHLISTGG

--------------------------------------------------------------
>92587_92587_6_TNFAIP1-EML1_TNFAIP1_chr17_26667505_ENST00000544907_EML1_chr14_100380614_ENST00000334192_length(transcript)=2705nt_BP=425nt
AAGTAGCTCTGCTCTCTCCGCGAAGACCCTCGGGGGATTCCGCCTCCACCCTTTCCCGGATAGAGCGCTATGCATGCAGGGACTTGTAGT
CTCAGGCTCCCCAGCCGGCTGGGCTGGGCAGCACTCCGGGCGGAGTCGACGAGCGCAGGATGTGAGCTCACAGCTTGGGACTGCTGAGGG
GCAGGCGGCTGCAGGCTAGGGGCGGCTCGGAGTCCGCTGGCCACCCAGCTGAGAGGAGAGGCGCCCCCGGGGACGGCTGGATCCTCATAG
ACCGTTGTGGAAAGCACTTTGGCACCATTTTGAATTACCTCCGAGATGACACCATCACCCTCCCTCAGAACCGGCAAGAAATCAAGGAAT
TGATGGCTGAAGCAAAGTATTACCTCATCCAGGGGCTGGTGAATATGTGCCAGAGTGCCCTGCAGTCAGGGGACTTCACACCCATTACTC
AGGGTCACACTGATGAGCTCTGGGGACTGGCCATCCATGCCTCAAAATCTCAGTTCTTGACCTGTGGGCATGACAAGCATGCCACTCTCT
GGGACGCTGTGGGTCACCGTCCCGTCTGGGACAAAATAATAGAGGATCCAGCTCAGTCTTCTGGTTTTCATCCTTCAGGGTCTGTGGTTG
CAGTCGGAACACTCACTGGGAGGTGGTTTGTGTTTGACACAGAAACAAAAGACTTGGTCACCGTTCACACAGATGGAAACGAACAGCTCT
CTGTAATGCGATACTCACCAGATGGGAATTTCTTAGCCATAGGCTCACATGACAACTGCATCTATATATATGGCGTTAGTGACAACGGGA
GGAAGTACACGCGAGTGGGCAAGTGCTCGGGTCATTCCAGCTTCATTACTCACCTGGACTGGTCTGTAAACTCACAGTTCCTCGTGTCAA
ATTCCGGAGACTACGAAATCCTCTACTGGGTTCCCTCTGCCTGTAAGCAAGTCGTAAGTGTGGAAACTACAAGAGACATTGAATGGGCTA
CCTATACCTGCACTTTGGGATTCCATGTTTTTGGAGTGTGGCCAGAAGGCTCGGACGGAACCGACATCAATGCCGTCTGTCGGGCCCATG
AGAAGAAACTCCTGTCAACAGGCGACGACTTTGGCAAAGTGCACCTCTTCTCATACCCCTGCTCGCAGTTCAGGGCTCCAAGCCACATCT
ACGGCGGGCACAGCAGCCATGTCACCAATGTCGATTTCCTCTGTGAAGACAGCCACCTCATCTCCACGGGCGGGAAAGACACAAGCATCA
TGCAGTGGCGCGTCATTTAGTACCCACCGAGAGCTGTGGGGAGCAGCATGGGCAAGGAAGACACAGACTCGCATTACCCTTGGTCACTGT
GATTTCTGTTTTGTTTAAAAAATTCTTACAAACCTCAGGAAAACTGTGCCCTCCGCCGGCTACCTTAGCTTAGCGTGTCAGCGGGCGCCA
CAGCGGATCAGCGGTTCCGTGTTCACTTTTGTTGTACAATATATGACACAGTGCACATTGAATACCAACAAGGTTGCAACGTTTACATTA
TAGCCACATCAACAGAAGTAACTGGTATATTCTTAGTAACTTTTCTATGAACTCTTCAAAAATGGTCACAGAATGCCTTTTAAAACATTG
TATATAATCTTCACTGTTTCACCATCTAGCTTGCTAAGTCAAATATTTATGATGATAATGAGGTACTGAACCACGATGGCTGTTGAGGAA
TTGGTCCTAAAAGGACAGATCACTTCAGAAGAGTGAATAACTGATTTGCACAGCTGAATCAGGAGACACAAAGATGAGACTGTGTTTGGT
TACATTTTCCAAAGTTTCATTGCATTCTCCCTTGGGGAGGCTGTGAGAGAGGGCTTGTATCCCTCTTGTGCTAAGCAGACTCTACTCCTA
ACTGACTTCAATATTTCAGCAGGGTACACAGGCGTTTCCAAGTTTCAGTGACACCGTCCTGCCTAACCAGATGCGGTCAGCCTCTTCACA
CCCACCTGGCTTGCATCCCCCATCCCTTGTTCACACGCCCTGATTCACGGTGAGACATTTTGCCACCTTCTTGTGTATATTACTTGGCAT
GAGATGATATTGTACTTGTATAGGATTCTAGCAATTCATAATAAATATGTAAGACTAGGCTTTACTGTCTTATGCTTATGGACATTGTAT
ATTTGTATTTTATGACCAAGTAGACCAAGTCAGAAAGATCTCTCTCGAGCGTACCATAAACCTGCAGAGAGAAGTCTCGAAAGGCTCCAC
CAGGTACCAAGGGCAGCTGCTTTTCCTGTCTTTTGTGCATGGGCGACCCATTACAGTATGAGATAAGATTGAGTTCTGATGCGTTAAACG
GAGGTGGCAGAAATTTGTCAAGAAGGCCTTATCCATTTCGATTGTGTGACAGATTGAAATTTATTGTTTACATTGGGGAATGTATCTCAA
ATTTTTAAATAGAAGAGTAATAAACAGACTTTAAAGCAAATATTAAGATTTTTACTCATTCAAGGCAAGTAAATGAATGGAATTATCTGA
GCTCTATGGCACTGGTTGTTTAGAGTGACTGATGAAGTGCAACTTTCAAAAACATTTTTGATGACATCACCAGCCTACTGCAGAAGTGCA
GGGCACCAGTAAACACCATGTATTATTGAAGATGAATCTGTTTGTATGTATCCTTGTCAAATATATTCTATAATGAAATAAAATCTGAAA

>92587_92587_6_TNFAIP1-EML1_TNFAIP1_chr17_26667505_ENST00000544907_EML1_chr14_100380614_ENST00000334192_length(amino acids)=371AA_BP=87
MGLLRGRRLQARGGSESAGHPAERRGAPGDGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQSGD
FTPITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTD
GNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTR
DIEWATYTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAPSHIYGGHSSHVTNVDFLCEDSHLISTGG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TNFAIP1-EML1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TNFAIP1-EML1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TNFAIP1-EML1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource