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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TNRC18-RNF216 (FusionGDB2 ID:92838)

Fusion Gene Summary for TNRC18-RNF216

check button Fusion gene summary
Fusion gene informationFusion gene name: TNRC18-RNF216
Fusion gene ID: 92838
HgeneTgene
Gene symbol

TNRC18

RNF216

Gene ID

84629

54476

Gene nametrinucleotide repeat containing 18ring finger protein 216
SynonymsCAGL79|TNRC18ACAHH|TRIAD3|U7I1|UBCE7IP1|ZIN
Cytomap

7p22.1

7p22.1

Type of geneprotein-codingprotein-coding
Descriptiontrinucleotide repeat-containing gene 18 proteinlong CAG trinucleotide repeat-containing gene 79 proteinE3 ubiquitin-protein ligase RNF216RING-type E3 ubiquitin transferase RNF216triad domain-containing protein 3ubiquitin-conjugating enzyme 7-interacting protein 1zinc finger protein inhibiting NF-kappa-B
Modification date2020031320200313
UniProtAcc.

Q9NWF9

Ensembl transtripts involved in fusion geneENST00000399434, ENST00000399537, 
ENST00000430969, 		ENST00000469375, 
ENST00000389902, ENST00000425013, 
Fusion gene scores* DoF score22 X 26 X 11=629217 X 18 X 11=3366
# samples 3933
** MAII scorelog2(39/6292*10)=-4.01197264166608
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(33/3366*10)=-3.35049724708413
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TNRC18 [Title/Abstract] AND RNF216 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTNRC18(5460691)-RNF216(5681007), # samples:6
Anticipated loss of major functional domain due to fusion event.TNRC18-RNF216 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneRNF216

GO:0032648

regulation of interferon-beta production

19893624

TgeneRNF216

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

19893624

TgeneRNF216

GO:0050691

regulation of defense response to virus by host

19893624

TgeneRNF216

GO:0070936

protein K48-linked ubiquitination

19893624


check buttonFusion gene breakpoints across TNRC18 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RNF216 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A0YT-01ATNRC18chr7

5410006

-RNF216chr7

5692141

-
ChimerDB4BRCATCGA-A2-A0YTTNRC18chr7

5410005

-RNF216chr7

5692141

-
ChimerDB4BRCATCGA-AN-A0FJ-01ATNRC18chr7

5410006

-RNF216chr7

5681007

-
ChimerDB4LUADTCGA-78-8660-01ATNRC18chr7

5434071

-RNF216chr7

5663756

-
ChimerDB4OVTCGA-13-0911-01ATNRC18chr7

5463072

-RNF216chr7

5692141

-
ChimerDB4OVTCGA-13-0911TNRC18chr7

5463071

-RNF216chr7

5692141

-
ChimerDB4OVTCGA-23-1030-01ATNRC18chr7

5410006

-RNF216chr7

5692141

-
ChimerDB4STADTCGA-CD-8524-01ATNRC18chr7

5446781

-RNF216chr7

5681007

-
ChimerDB4STADTCGA-CD-8524-01ATNRC18chr7

5460691

-RNF216chr7

5681007

-
ChimerDB4STADTCGA-CD-8524TNRC18chr7

5460690

-RNF216chr7

5681007

-
ChimerDB4UCECTCGA-A5-A2K4-01ATNRC18chr7

5446781

-RNF216chr7

5681007

-
ChimerDB4UCECTCGA-A5-A2K4-01ATNRC18chr7

5460691

-RNF216chr7

5681007

-
ChimerDB4UCECTCGA-A5-A2K4-01ATNRC18chr7

5463072

-RNF216chr7

5681007

-
ChimerDB4UCECTCGA-A5-A2K4TNRC18chr7

5460690

-RNF216chr7

5681007

-
ChimerDB4UCECTCGA-A5-A2K4TNRC18chr7

5463071

-RNF216chr7

5681007

-
ChimerDB4UCECTCGA-AX-A3FX-01ATNRC18chr7

5446781

-RNF216chr7

5681007

-
ChimerDB4UCECTCGA-AX-A3FX-01ATNRC18chr7

5460691

-RNF216chr7

5681007

-
ChimerDB4UCECTCGA-AX-A3FX-01ATNRC18chr7

5463072

-RNF216chr7

5681007

-
ChimerDB4UCECTCGA-AX-A3FX-01ATNRC18chr7

5464922

-RNF216chr7

5681007

-
ChimerDB4UCECTCGA-AX-A3FXTNRC18chr7

5460690

-RNF216chr7

5681007

-
ChimerDB4UCECTCGA-B5-A3S1-01ATNRC18chr7

5399029

-RNF216chr7

5765069

-
ChimerDB4UCECTCGA-B5-A3S1TNRC18chr7

5399028

-RNF216chr7

5765069

-


Top

Fusion Gene ORF analysis for TNRC18-RNF216

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000399434ENST00000469375TNRC18chr7

5434071

-RNF216chr7

5663756

-
5CDS-5UTRENST00000399537ENST00000469375TNRC18chr7

5410006

-RNF216chr7

5681007

-
5CDS-5UTRENST00000399537ENST00000469375TNRC18chr7

5434071

-RNF216chr7

5663756

-
5CDS-5UTRENST00000399537ENST00000469375TNRC18chr7

5460691

-RNF216chr7

5681007

-
5CDS-5UTRENST00000399537ENST00000469375TNRC18chr7

5460690

-RNF216chr7

5681007

-
5CDS-5UTRENST00000430969ENST00000469375TNRC18chr7

5410006

-RNF216chr7

5681007

-
5CDS-5UTRENST00000430969ENST00000469375TNRC18chr7

5434071

-RNF216chr7

5663756

-
5CDS-5UTRENST00000430969ENST00000469375TNRC18chr7

5460691

-RNF216chr7

5681007

-
5CDS-5UTRENST00000430969ENST00000469375TNRC18chr7

5460690

-RNF216chr7

5681007

-
5CDS-intronENST00000399537ENST00000469375TNRC18chr7

5410006

-RNF216chr7

5692141

-
5CDS-intronENST00000399537ENST00000469375TNRC18chr7

5410005

-RNF216chr7

5692141

-
5CDS-intronENST00000399537ENST00000469375TNRC18chr7

5399029

-RNF216chr7

5765069

-
5CDS-intronENST00000399537ENST00000469375TNRC18chr7

5399028

-RNF216chr7

5765069

-
5CDS-intronENST00000430969ENST00000469375TNRC18chr7

5410006

-RNF216chr7

5692141

-
5CDS-intronENST00000430969ENST00000469375TNRC18chr7

5410005

-RNF216chr7

5692141

-
5CDS-intronENST00000430969ENST00000469375TNRC18chr7

5399029

-RNF216chr7

5765069

-
5CDS-intronENST00000430969ENST00000469375TNRC18chr7

5399028

-RNF216chr7

5765069

-
5UTR-3CDSENST00000399434ENST00000389902TNRC18chr7

5464922

-RNF216chr7

5681007

-
5UTR-3CDSENST00000399434ENST00000425013TNRC18chr7

5464922

-RNF216chr7

5681007

-
5UTR-3CDSENST00000399537ENST00000389902TNRC18chr7

5463072

-RNF216chr7

5692141

-
5UTR-3CDSENST00000399537ENST00000389902TNRC18chr7

5463071

-RNF216chr7

5692141

-
5UTR-3CDSENST00000399537ENST00000389902TNRC18chr7

5463072

-RNF216chr7

5681007

-
5UTR-3CDSENST00000399537ENST00000389902TNRC18chr7

5463071

-RNF216chr7

5681007

-
5UTR-3CDSENST00000399537ENST00000425013TNRC18chr7

5463072

-RNF216chr7

5692141

-
5UTR-3CDSENST00000399537ENST00000425013TNRC18chr7

5463071

-RNF216chr7

5692141

-
5UTR-3CDSENST00000399537ENST00000425013TNRC18chr7

5463072

-RNF216chr7

5681007

-
5UTR-3CDSENST00000399537ENST00000425013TNRC18chr7

5463071

-RNF216chr7

5681007

-
5UTR-3CDSENST00000430969ENST00000389902TNRC18chr7

5463072

-RNF216chr7

5692141

-
5UTR-3CDSENST00000430969ENST00000389902TNRC18chr7

5463071

-RNF216chr7

5692141

-
5UTR-3CDSENST00000430969ENST00000389902TNRC18chr7

5463072

-RNF216chr7

5681007

-
5UTR-3CDSENST00000430969ENST00000389902TNRC18chr7

5463071

-RNF216chr7

5681007

-
5UTR-3CDSENST00000430969ENST00000425013TNRC18chr7

5463072

-RNF216chr7

5692141

-
5UTR-3CDSENST00000430969ENST00000425013TNRC18chr7

5463071

-RNF216chr7

5692141

-
5UTR-3CDSENST00000430969ENST00000425013TNRC18chr7

5463072

-RNF216chr7

5681007

-
5UTR-3CDSENST00000430969ENST00000425013TNRC18chr7

5463071

-RNF216chr7

5681007

-
5UTR-5UTRENST00000399434ENST00000469375TNRC18chr7

5464922

-RNF216chr7

5681007

-
5UTR-5UTRENST00000399537ENST00000469375TNRC18chr7

5463072

-RNF216chr7

5681007

-
5UTR-5UTRENST00000399537ENST00000469375TNRC18chr7

5463071

-RNF216chr7

5681007

-
5UTR-5UTRENST00000430969ENST00000469375TNRC18chr7

5463072

-RNF216chr7

5681007

-
5UTR-5UTRENST00000430969ENST00000469375TNRC18chr7

5463071

-RNF216chr7

5681007

-
5UTR-intronENST00000399537ENST00000469375TNRC18chr7

5463072

-RNF216chr7

5692141

-
5UTR-intronENST00000399537ENST00000469375TNRC18chr7

5463071

-RNF216chr7

5692141

-
5UTR-intronENST00000430969ENST00000469375TNRC18chr7

5463072

-RNF216chr7

5692141

-
5UTR-intronENST00000430969ENST00000469375TNRC18chr7

5463071

-RNF216chr7

5692141

-
Frame-shiftENST00000399434ENST00000389902TNRC18chr7

5434071

-RNF216chr7

5663756

-
Frame-shiftENST00000399434ENST00000425013TNRC18chr7

5434071

-RNF216chr7

5663756

-
Frame-shiftENST00000399537ENST00000389902TNRC18chr7

5410006

-RNF216chr7

5681007

-
Frame-shiftENST00000399537ENST00000389902TNRC18chr7

5460691

-RNF216chr7

5681007

-
Frame-shiftENST00000399537ENST00000389902TNRC18chr7

5460690

-RNF216chr7

5681007

-
Frame-shiftENST00000399537ENST00000389902TNRC18chr7

5399029

-RNF216chr7

5765069

-
Frame-shiftENST00000399537ENST00000389902TNRC18chr7

5399028

-RNF216chr7

5765069

-
Frame-shiftENST00000399537ENST00000425013TNRC18chr7

5410006

-RNF216chr7

5681007

-
Frame-shiftENST00000399537ENST00000425013TNRC18chr7

5460691

-RNF216chr7

5681007

-
Frame-shiftENST00000399537ENST00000425013TNRC18chr7

5460690

-RNF216chr7

5681007

-
Frame-shiftENST00000399537ENST00000425013TNRC18chr7

5399029

-RNF216chr7

5765069

-
Frame-shiftENST00000399537ENST00000425013TNRC18chr7

5399028

-RNF216chr7

5765069

-
Frame-shiftENST00000430969ENST00000389902TNRC18chr7

5410006

-RNF216chr7

5681007

-
Frame-shiftENST00000430969ENST00000389902TNRC18chr7

5460691

-RNF216chr7

5681007

-
Frame-shiftENST00000430969ENST00000389902TNRC18chr7

5460690

-RNF216chr7

5681007

-
Frame-shiftENST00000430969ENST00000389902TNRC18chr7

5399029

-RNF216chr7

5765069

-
Frame-shiftENST00000430969ENST00000389902TNRC18chr7

5399028

-RNF216chr7

5765069

-
Frame-shiftENST00000430969ENST00000425013TNRC18chr7

5410006

-RNF216chr7

5681007

-
Frame-shiftENST00000430969ENST00000425013TNRC18chr7

5460691

-RNF216chr7

5681007

-
Frame-shiftENST00000430969ENST00000425013TNRC18chr7

5460690

-RNF216chr7

5681007

-
Frame-shiftENST00000430969ENST00000425013TNRC18chr7

5399029

-RNF216chr7

5765069

-
Frame-shiftENST00000430969ENST00000425013TNRC18chr7

5399028

-RNF216chr7

5765069

-
In-frameENST00000399537ENST00000389902TNRC18chr7

5410006

-RNF216chr7

5692141

-
In-frameENST00000399537ENST00000389902TNRC18chr7

5410005

-RNF216chr7

5692141

-
In-frameENST00000399537ENST00000389902TNRC18chr7

5434071

-RNF216chr7

5663756

-
In-frameENST00000399537ENST00000425013TNRC18chr7

5410006

-RNF216chr7

5692141

-
In-frameENST00000399537ENST00000425013TNRC18chr7

5410005

-RNF216chr7

5692141

-
In-frameENST00000399537ENST00000425013TNRC18chr7

5434071

-RNF216chr7

5663756

-
In-frameENST00000430969ENST00000389902TNRC18chr7

5410006

-RNF216chr7

5692141

-
In-frameENST00000430969ENST00000389902TNRC18chr7

5410005

-RNF216chr7

5692141

-
In-frameENST00000430969ENST00000389902TNRC18chr7

5434071

-RNF216chr7

5663756

-
In-frameENST00000430969ENST00000425013TNRC18chr7

5410006

-RNF216chr7

5692141

-
In-frameENST00000430969ENST00000425013TNRC18chr7

5410005

-RNF216chr7

5692141

-
In-frameENST00000430969ENST00000425013TNRC18chr7

5434071

-RNF216chr7

5663756

-
intron-3CDSENST00000399434ENST00000389902TNRC18chr7

5410006

-RNF216chr7

5692141

-
intron-3CDSENST00000399434ENST00000389902TNRC18chr7

5410005

-RNF216chr7

5692141

-
intron-3CDSENST00000399434ENST00000389902TNRC18chr7

5410006

-RNF216chr7

5681007

-
intron-3CDSENST00000399434ENST00000389902TNRC18chr7

5463072

-RNF216chr7

5692141

-
intron-3CDSENST00000399434ENST00000389902TNRC18chr7

5463071

-RNF216chr7

5692141

-
intron-3CDSENST00000399434ENST00000389902TNRC18chr7

5460691

-RNF216chr7

5681007

-
intron-3CDSENST00000399434ENST00000389902TNRC18chr7

5460690

-RNF216chr7

5681007

-
intron-3CDSENST00000399434ENST00000389902TNRC18chr7

5463072

-RNF216chr7

5681007

-
intron-3CDSENST00000399434ENST00000389902TNRC18chr7

5463071

-RNF216chr7

5681007

-
intron-3CDSENST00000399434ENST00000389902TNRC18chr7

5446781

-RNF216chr7

5681007

-
intron-3CDSENST00000399434ENST00000389902TNRC18chr7

5399029

-RNF216chr7

5765069

-
intron-3CDSENST00000399434ENST00000389902TNRC18chr7

5399028

-RNF216chr7

5765069

-
intron-3CDSENST00000399434ENST00000425013TNRC18chr7

5410006

-RNF216chr7

5692141

-
intron-3CDSENST00000399434ENST00000425013TNRC18chr7

5410005

-RNF216chr7

5692141

-
intron-3CDSENST00000399434ENST00000425013TNRC18chr7

5410006

-RNF216chr7

5681007

-
intron-3CDSENST00000399434ENST00000425013TNRC18chr7

5463072

-RNF216chr7

5692141

-
intron-3CDSENST00000399434ENST00000425013TNRC18chr7

5463071

-RNF216chr7

5692141

-
intron-3CDSENST00000399434ENST00000425013TNRC18chr7

5460691

-RNF216chr7

5681007

-
intron-3CDSENST00000399434ENST00000425013TNRC18chr7

5460690

-RNF216chr7

5681007

-
intron-3CDSENST00000399434ENST00000425013TNRC18chr7

5463072

-RNF216chr7

5681007

-
intron-3CDSENST00000399434ENST00000425013TNRC18chr7

5463071

-RNF216chr7

5681007

-
intron-3CDSENST00000399434ENST00000425013TNRC18chr7

5446781

-RNF216chr7

5681007

-
intron-3CDSENST00000399434ENST00000425013TNRC18chr7

5399029

-RNF216chr7

5765069

-
intron-3CDSENST00000399434ENST00000425013TNRC18chr7

5399028

-RNF216chr7

5765069

-
intron-3CDSENST00000399537ENST00000389902TNRC18chr7

5446781

-RNF216chr7

5681007

-
intron-3CDSENST00000399537ENST00000389902TNRC18chr7

5464922

-RNF216chr7

5681007

-
intron-3CDSENST00000399537ENST00000425013TNRC18chr7

5446781

-RNF216chr7

5681007

-
intron-3CDSENST00000399537ENST00000425013TNRC18chr7

5464922

-RNF216chr7

5681007

-
intron-3CDSENST00000430969ENST00000389902TNRC18chr7

5446781

-RNF216chr7

5681007

-
intron-3CDSENST00000430969ENST00000389902TNRC18chr7

5464922

-RNF216chr7

5681007

-
intron-3CDSENST00000430969ENST00000425013TNRC18chr7

5446781

-RNF216chr7

5681007

-
intron-3CDSENST00000430969ENST00000425013TNRC18chr7

5464922

-RNF216chr7

5681007

-
intron-5UTRENST00000399434ENST00000469375TNRC18chr7

5410006

-RNF216chr7

5681007

-
intron-5UTRENST00000399434ENST00000469375TNRC18chr7

5460691

-RNF216chr7

5681007

-
intron-5UTRENST00000399434ENST00000469375TNRC18chr7

5460690

-RNF216chr7

5681007

-
intron-5UTRENST00000399434ENST00000469375TNRC18chr7

5463072

-RNF216chr7

5681007

-
intron-5UTRENST00000399434ENST00000469375TNRC18chr7

5463071

-RNF216chr7

5681007

-
intron-5UTRENST00000399434ENST00000469375TNRC18chr7

5446781

-RNF216chr7

5681007

-
intron-5UTRENST00000399537ENST00000469375TNRC18chr7

5446781

-RNF216chr7

5681007

-
intron-5UTRENST00000399537ENST00000469375TNRC18chr7

5464922

-RNF216chr7

5681007

-
intron-5UTRENST00000430969ENST00000469375TNRC18chr7

5446781

-RNF216chr7

5681007

-
intron-5UTRENST00000430969ENST00000469375TNRC18chr7

5464922

-RNF216chr7

5681007

-
intron-intronENST00000399434ENST00000469375TNRC18chr7

5410006

-RNF216chr7

5692141

-
intron-intronENST00000399434ENST00000469375TNRC18chr7

5410005

-RNF216chr7

5692141

-
intron-intronENST00000399434ENST00000469375TNRC18chr7

5463072

-RNF216chr7

5692141

-
intron-intronENST00000399434ENST00000469375TNRC18chr7

5463071

-RNF216chr7

5692141

-
intron-intronENST00000399434ENST00000469375TNRC18chr7

5399029

-RNF216chr7

5765069

-
intron-intronENST00000399434ENST00000469375TNRC18chr7

5399028

-RNF216chr7

5765069

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000399537TNRC18chr75410006-ENST00000425013RNF216chr75692141-8092456832545781417
ENST00000399537TNRC18chr75410006-ENST00000389902RNF216chr75692141-5532456832545781417
ENST00000430969TNRC18chr75410006-ENST00000425013RNF216chr75692141-8092456832545781417
ENST00000430969TNRC18chr75410006-ENST00000389902RNF216chr75692141-5532456832545781417
ENST00000399537TNRC18chr75434071-ENST00000425013RNF216chr75663756-38956927801260
ENST00000399537TNRC18chr75434071-ENST00000389902RNF216chr75663756-133569233620195
ENST00000430969TNRC18chr75434071-ENST00000425013RNF216chr75663756-38956927801260
ENST00000430969TNRC18chr75434071-ENST00000389902RNF216chr75663756-133569233620195
ENST00000399537TNRC18chr75410005-ENST00000425013RNF216chr75692141-8092456832545781417
ENST00000399537TNRC18chr75410005-ENST00000389902RNF216chr75692141-5532456832545781417
ENST00000430969TNRC18chr75410005-ENST00000425013RNF216chr75692141-8092456832545781417
ENST00000430969TNRC18chr75410005-ENST00000389902RNF216chr75692141-5532456832545781417

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000399537ENST00000425013TNRC18chr75410006-RNF216chr75692141-0.0075288870.9924711
ENST00000399537ENST00000389902TNRC18chr75410006-RNF216chr75692141-0.0106186040.98938143
ENST00000430969ENST00000425013TNRC18chr75410006-RNF216chr75692141-0.0075288870.9924711
ENST00000430969ENST00000389902TNRC18chr75410006-RNF216chr75692141-0.0106186040.98938143
ENST00000399537ENST00000425013TNRC18chr75434071-RNF216chr75663756-0.0128538820.98714614
ENST00000399537ENST00000389902TNRC18chr75434071-RNF216chr75663756-0.0120836210.98791635
ENST00000430969ENST00000425013TNRC18chr75434071-RNF216chr75663756-0.0128538820.98714614
ENST00000430969ENST00000389902TNRC18chr75434071-RNF216chr75663756-0.0120836210.98791635
ENST00000399537ENST00000425013TNRC18chr75410005-RNF216chr75692141-0.0075288870.9924711
ENST00000399537ENST00000389902TNRC18chr75410005-RNF216chr75692141-0.0106186040.98938143
ENST00000430969ENST00000425013TNRC18chr75410005-RNF216chr75692141-0.0075288870.9924711
ENST00000430969ENST00000389902TNRC18chr75410005-RNF216chr75692141-0.0106186040.98938143

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Fusion Genomic Features for TNRC18-RNF216


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TNRC18-RNF216


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:5460691/chr7:5681007)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.RNF216

Q9NWF9

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Isoform 1 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Promotes degradation of TRAF3, TLR4 and TLR9. Contributes to the regulation of antiviral responses. Down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production. Isoform 3 inhibits TNF and IL-1 mediated activation of NF-kappa-B. Promotes TNF and RIP mediated apoptosis. {ECO:0000269|PubMed:15107846, ECO:0000269|PubMed:19893624}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTNRC18chr7:5410005chr7:5692141ENST00000430969-1130916_94914062969.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC18chr7:5410006chr7:5692141ENST00000430969-1130916_94914062969.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC18chr7:5410005chr7:5692141ENST00000430969-1130326_50614062969.0Compositional biasNote=Pro-rich
HgeneTNRC18chr7:5410005chr7:5692141ENST00000430969-1130968_119214062969.0Compositional biasNote=Pro-rich
HgeneTNRC18chr7:5410006chr7:5692141ENST00000430969-1130326_50614062969.0Compositional biasNote=Pro-rich
HgeneTNRC18chr7:5410006chr7:5692141ENST00000430969-1130968_119214062969.0Compositional biasNote=Pro-rich
TgeneRNF216chr7:5410005chr7:5692141ENST000003899021217737_763687924.0Coiled coilOntology_term=ECO:0000255
TgeneRNF216chr7:5410005chr7:5692141ENST000004250131217737_763630867.0Coiled coilOntology_term=ECO:0000255
TgeneRNF216chr7:5410006chr7:5692141ENST000003899021217737_763687924.0Coiled coilOntology_term=ECO:0000255
TgeneRNF216chr7:5410006chr7:5692141ENST000004250131217737_763630867.0Coiled coilOntology_term=ECO:0000255
TgeneRNF216chr7:5434071chr7:5663756ENST000004250131417737_763737867.0Coiled coilOntology_term=ECO:0000255
TgeneRNF216chr7:5410005chr7:5692141ENST000003899021217769_862687924.0Compositional biasNote=Pro-rich
TgeneRNF216chr7:5410005chr7:5692141ENST000004250131217769_862630867.0Compositional biasNote=Pro-rich
TgeneRNF216chr7:5410006chr7:5692141ENST000003899021217769_862687924.0Compositional biasNote=Pro-rich
TgeneRNF216chr7:5410006chr7:5692141ENST000004250131217769_862630867.0Compositional biasNote=Pro-rich
TgeneRNF216chr7:5434071chr7:5663756ENST000004250131417769_862737867.0Compositional biasNote=Pro-rich
TgeneRNF216chr7:5410005chr7:5692141ENST000004250131217675_703630867.0Zinc fingerRING-type 2%3B atypical
TgeneRNF216chr7:5410006chr7:5692141ENST000004250131217675_703630867.0Zinc fingerRING-type 2%3B atypical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTNRC18chr7:5410005chr7:5692141ENST00000430969-11301481_151614062969.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC18chr7:5410006chr7:5692141ENST00000430969-11301481_151614062969.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC18chr7:5434071chr7:5663756ENST00000430969-3301481_15161142969.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC18chr7:5434071chr7:5663756ENST00000430969-330916_9491142969.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC18chr7:5410005chr7:5692141ENST00000430969-11301828_184114062969.0Compositional biasNote=Poly-Glu
HgeneTNRC18chr7:5410005chr7:5692141ENST00000430969-11302353_243714062969.0Compositional biasNote=Pro-rich
HgeneTNRC18chr7:5410005chr7:5692141ENST00000430969-11302557_268114062969.0Compositional biasNote=Ser-rich
HgeneTNRC18chr7:5410006chr7:5692141ENST00000430969-11301828_184114062969.0Compositional biasNote=Poly-Glu
HgeneTNRC18chr7:5410006chr7:5692141ENST00000430969-11302353_243714062969.0Compositional biasNote=Pro-rich
HgeneTNRC18chr7:5410006chr7:5692141ENST00000430969-11302557_268114062969.0Compositional biasNote=Ser-rich
HgeneTNRC18chr7:5434071chr7:5663756ENST00000430969-3301828_18411142969.0Compositional biasNote=Poly-Glu
HgeneTNRC18chr7:5434071chr7:5663756ENST00000430969-3302353_24371142969.0Compositional biasNote=Pro-rich
HgeneTNRC18chr7:5434071chr7:5663756ENST00000430969-3302557_26811142969.0Compositional biasNote=Ser-rich
HgeneTNRC18chr7:5434071chr7:5663756ENST00000430969-330326_5061142969.0Compositional biasNote=Pro-rich
HgeneTNRC18chr7:5434071chr7:5663756ENST00000430969-330968_11921142969.0Compositional biasNote=Pro-rich
HgeneTNRC18chr7:5410005chr7:5692141ENST00000430969-11302817_296214062969.0DomainBAH
HgeneTNRC18chr7:5410006chr7:5692141ENST00000430969-11302817_296214062969.0DomainBAH
HgeneTNRC18chr7:5434071chr7:5663756ENST00000430969-3302817_29621142969.0DomainBAH
TgeneRNF216chr7:5410005chr7:5692141ENST000003899021217475_491687924.0Coiled coilOntology_term=ECO:0000255
TgeneRNF216chr7:5410005chr7:5692141ENST000004250131217475_491630867.0Coiled coilOntology_term=ECO:0000255
TgeneRNF216chr7:5410006chr7:5692141ENST000003899021217475_491687924.0Coiled coilOntology_term=ECO:0000255
TgeneRNF216chr7:5410006chr7:5692141ENST000004250131217475_491630867.0Coiled coilOntology_term=ECO:0000255
TgeneRNF216chr7:5434071chr7:5663756ENST000003899021417475_491794924.0Coiled coilOntology_term=ECO:0000255
TgeneRNF216chr7:5434071chr7:5663756ENST000003899021417737_763794924.0Coiled coilOntology_term=ECO:0000255
TgeneRNF216chr7:5434071chr7:5663756ENST000004250131417475_491737867.0Coiled coilOntology_term=ECO:0000255
TgeneRNF216chr7:5434071chr7:5663756ENST000003899021417769_862794924.0Compositional biasNote=Pro-rich
TgeneRNF216chr7:5410005chr7:5692141ENST000003899021217511_728687924.0RegionTRIAD supradomain
TgeneRNF216chr7:5410005chr7:5692141ENST000004250131217511_728630867.0RegionTRIAD supradomain
TgeneRNF216chr7:5410006chr7:5692141ENST000003899021217511_728687924.0RegionTRIAD supradomain
TgeneRNF216chr7:5410006chr7:5692141ENST000004250131217511_728630867.0RegionTRIAD supradomain
TgeneRNF216chr7:5434071chr7:5663756ENST000003899021417511_728794924.0RegionTRIAD supradomain
TgeneRNF216chr7:5434071chr7:5663756ENST000004250131417511_728737867.0RegionTRIAD supradomain
TgeneRNF216chr7:5410005chr7:5692141ENST000003899021217515_564687924.0Zinc fingerRING-type 1
TgeneRNF216chr7:5410005chr7:5692141ENST000003899021217583_648687924.0Zinc fingerIBR-type
TgeneRNF216chr7:5410005chr7:5692141ENST000003899021217675_703687924.0Zinc fingerRING-type 2%3B atypical
TgeneRNF216chr7:5410005chr7:5692141ENST000004250131217515_564630867.0Zinc fingerRING-type 1
TgeneRNF216chr7:5410005chr7:5692141ENST000004250131217583_648630867.0Zinc fingerIBR-type
TgeneRNF216chr7:5410006chr7:5692141ENST000003899021217515_564687924.0Zinc fingerRING-type 1
TgeneRNF216chr7:5410006chr7:5692141ENST000003899021217583_648687924.0Zinc fingerIBR-type
TgeneRNF216chr7:5410006chr7:5692141ENST000003899021217675_703687924.0Zinc fingerRING-type 2%3B atypical
TgeneRNF216chr7:5410006chr7:5692141ENST000004250131217515_564630867.0Zinc fingerRING-type 1
TgeneRNF216chr7:5410006chr7:5692141ENST000004250131217583_648630867.0Zinc fingerIBR-type
TgeneRNF216chr7:5434071chr7:5663756ENST000003899021417515_564794924.0Zinc fingerRING-type 1
TgeneRNF216chr7:5434071chr7:5663756ENST000003899021417583_648794924.0Zinc fingerIBR-type
TgeneRNF216chr7:5434071chr7:5663756ENST000003899021417675_703794924.0Zinc fingerRING-type 2%3B atypical
TgeneRNF216chr7:5434071chr7:5663756ENST000004250131417515_564737867.0Zinc fingerRING-type 1
TgeneRNF216chr7:5434071chr7:5663756ENST000004250131417583_648737867.0Zinc fingerIBR-type
TgeneRNF216chr7:5434071chr7:5663756ENST000004250131417675_703737867.0Zinc fingerRING-type 2%3B atypical


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Fusion Gene Sequence for TNRC18-RNF216


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>92838_92838_1_TNRC18-RNF216_TNRC18_chr7_5410005_ENST00000399537_RNF216_chr7_5692141_ENST00000389902_length(transcript)=5532nt_BP=4568nt
GGCCGCGGGATGGCGGGCAGCAGGGGCGCCTAGCTGCGCCGGGAGCCGGGGCCGCCGCCGGAGTCGTTGTCGCCGGAGCCTGGAGCCGTG
AACCCAGCCGCGCCAGACGCCGTGTGCGCCGCCTCGCGCAGCTCCGCCTGGCCGCCCGGAGGGGCCCCACCGCCGGCCGCCTGTGCGCCC
CGGGCCGCGGGCCCGCCGCCGAGCGCAAGCCCCGCTGGCCGCCGCCATGCACGCCGCGGAGCCCCCGCCGCCCGAGGACTCTGGGACTAC
GCCGAGGCCGAACTTTTAGGTCCCACTGAGCTAGGCCTGCGGGCCGGGTGGGGGGCTGATCGCGGCACTCCCGCGGAGGATGGATGGCCG
AGACTTCGGGCCCCAGCGGTCCGTGCACGGTCCCCCGCCGCCGCTGCTGTCCGGCCTGGCCATGGACAGCCACCGCGTGGGCGCGGCCAC
TGCCGGACGCTTGCCCGCCTCGGGCTTGCCCGGCCCGCTGCCGCCCGGGAAGTACATGGCCGGCCTGAATCTCCATCCGCACCCGGGCGA
GGCCTTCTTGGGCAGCTTTGTGGCCAGCGGGATGGGGCCCTCGGCCTCGTCCCATGGGAGCCCAGTGCCACTGCCCTCTGACCTGTCTTT
CCGCTCCCCAACCCCTAGCAACCTGCCCATGGTGCAGCTGTGGGCCGCCCACGCCCATGAAGGCTTCTCCCACCTGCCCAGTGGGCTGTA
CCCATCCTACCTCCACCTGAACCACCTGGAGCCCCCCAGCAGTGGGAGCCCCCTCCTCAGCCAGCTGGGTCAGCCCAGCATTTTCGATAC
CCAGAAAGGTCAGGGGCCAGGAGGAGACGGTTTCTACCTGCCCACCGCGGGGGCTCCGGGCTCCCTGCACTCTCACGCGCCCTCGGCCCG
GACCCCTGGCGGCGGCCACTCCTCGGGCGCCCCGGCCAAAGGCTCGTCGTCGCGGGACGGTCCAGCCAAGGAGCGGGCGGGCCGCGGCGG
GGAGCCGCCTCCGCTTTTCGGCAAGAAGGACCCGCGCGCCCGGGGCGAGGAGGCCTCGGGGCCACGGGGCGTGGTGGACCTGACCCAGGA
GGCGCGCGCCGAGGGCCGCCAGGACCGGGGGCCCCCGCGCCTGGCTGAGCGCCTGTCGCCCTTCCTGGCTGAGTCCAAGACCAAGAATGC
GGCGCTGCAGCCGTCGGTACTGACCATGTGCAACGGCGGCGCCGGGGACGTGGGGCTGCCCGCGCTGGTGGCCGAAGCGGGGCGCGGGGG
TGCCAAGGAGGCTGCCCGGCAGGACGAGGGCGCGCGGCTGCTGCGGCGCACGGAGACCCTGCTCCCTGGGCCGCGCCCCTGCCCCTCACC
GCTGCCCCCGCCGCCCGCGCCCCCCAAGGGGCCTCCTGCACCCCCCGCGGCCACCCCCGCCGGCGTCTACACCGTCTTCCGCGAGCAGGG
CCGTGAGCACCGCGTGGTGGCGCCCACCTTCGTGCCTTCCGTGGAGGCCTTCGACGAGCGCCCGGGGCCCATCCAGATCGCATCCCAGGC
GCGCGATGCCCGGGCCCGCGAGCGCGAGGCTGGCAGGCCAGGGGTCCTGCAGGCGCCCCCCGGCTCCCCGCGGCCTCTGGACCGGCCCGA
GGGCCTGCGCGAGAAGAACTCGGTCATCCGCTCGCTCAAGCGGCCGCCCCCCGCGGATGCCCCCACGGTGCGGGCCACACGCGCCTCCCC
GGACCCCCGCGCCTACGTGCCTGCCAAGGAGCTGCTCAAGCCCGAGGCGGACCCGAGGCCCTGCGAGCGTGCGCCCCGCGGCCCAGCCGG
TCCTGCAGCCCAACAGGCCGCCAAGCTCTTCGGCCTGGAGCCCGGGCGCCCCCCGCCCACCGGCCCTGAGCATAAATGGAAACCCTTCGA
GCTGGGCAACTTCGCCGCCACGCAGATGGCCGTGCTGGCCGCGCAGCACCACCACAGCCGCGCCGAAGAGGAGGCCGCCGTGGTCGCTGC
CTCCTCCTCCAAGAAGGCCTACCTGGACCCTGGGGCTGTGCTGCCCCGCTCGGCGGCCACCTGCGGCCGGCCGGTCGCTGACATGCACTC
TGCGGCCCACGGGTCTGGAGAGGCCTCGGCCATGCAGAGCCTTATAAAGTACAGTGGCAGCTTTGCCCGGGACGCCGTGGCCGTGCGCCC
TGGTGGCTGTGGCAAGAAGAGCCCCTTTGGAGGTTTGGGCACCATGAAACCCGAGCCTGCGCCCACCTCTGCGGGTGCCTCCCGAGCCCA
GGCCCGTCTCCCACACTCCGGAGGCCCTGCAGCGGGCGGCGGCCGGCAGCTGAAGCGGGACCCCGAGAGGCCCGAGAGCGCCAAAGCTTT
CGGGCGCGAGGGCTCTGGTGCCCAGGGTGAGGCAGAAGTGCGACACCCGCCTGTGGGCATTGCAGTGGCTGTGGCCCGGCAGAAGGACAG
TGGCGGCAGTGGCCGGCTGGGGCCTGGGCTGGTAGACCAGGAGCGCTCTCTGTCGCTGAGTAACGTCAAAGGGCACGGCCGAGCAGATGA
GGACTGTGTGGACGACCGGGCCAGACACCGGGAGGAACGGCTGCTCGGGGCACGGCTGGACCGGGATCAGGAGAAGCTGCTCAGAGAGAG
TAAGGAGCTGGCTGACCTGGCCCGCCTGCACCCTACCAGCTGTGCTCCTAACGGCCTGAACCCCAACCTCATGGTGACGGGGGGCCCGGC
GCTGGCGGGCTCAGGTCGCTGGTCTGCCGACCCCGCAGCCCATCTGGCCACGCACCCCTGGTTGCCCCGCTCGGGCAACGCATCCATGTG
GCTCGCTGGACACCCCTACGGCTTGGGTCCCCCATCTCTGCACCAGGGCATGGCCCCTGCGTTCCCACCTGGCCTGGGGGGCTCCCTCCC
GTCAGCCTACCAGTTTGTCAGGGACCCCCAATCGGGCCAGCTGGTGGTCATTCCCAGTGATCACCTTCCTCACTTTGCGGAGCTGATGGA
GCGGGCCACCGTACCGCCCCTCTGGCCCGCCCTGTACCCGCCGGGCCGCAGCCCCCTGCACCACGCCCAGCAGCTGCAGCTCTTCTCACA
GCAGCACTTCCTGCGGCAGCAGGAGTTCCTGTACCTGCAGCAGCAGGCGGCCCAGGCCTTGGAACTGCAGAGGAGCGCCCAGCTCGTGCA
GGAGCGGTTGAAGGCGCAGGAGCACCGGGCGGAGATGGAAGAGAAGGGGAGCAAGCGGGGCCTGGAGGCTGCGGGCAAGGCTGGCCTGGC
CACCGCCGGCCCCGGGCTGCTGCCGCGGAAGCCCCCTGGCCTGGCCGCCGGCCCCGCGGGCACCTACGGCAAGGCCGTGAGCCCGCCACC
ATCACCCCGCGCATCCCCTGTGGCTGCCCTGAAGGCCAAGGTCATCCAGAAGCTGGAGGACGTGTCCAAGCCACCCGCCTACGCCTACCC
CGCCACCCCCAGCTCCCACCCCACCAGCCCGCCGCCCGCCTCCCCACCGCCCACCCCGGGTATCACCCGCAAGGAGGAGGCTCCCGAGAA
TGTGGTCGAGAAGAAAGACTTGGAGTTGGAGAAGGAAGCCCCCAGCCCCTTCCAGGCCCTGTTCTCAGATATCCCGCCCAGGTACCCGTT
CCAAGCCCTGCCACCGCACTACGGGAGGCCCTACCCTTTCCTGCTGCAGCCCACGGCCGCCGCCGACGCGGACGGCTTGGCCCCTGATGT
GCCGCTCCCGGCTGATGGGCCCGAGCGCCTGGCACTCTCACCCGAAGACAAGCCCATCCGCTTGTCCCCCTCCAAGATCACAGAGCCGCT
GCGGGAGGGCCCGGAGGAAGAACCGCTGGCTGAGCGGGAGGTGAAGGCAGAGGTGGAGGACATGGACGAGGGCCCCACAGAGCTGCCGCC
TCTGGAGTCGCCGCTGCCACTGCCCGCCGCGGAAGCCATGGCTACCCCCAGCCCTGCAGGGGGTTGTGGAGGTGGCCTGTTGGAGGCCCA
GGCGCTGAGTGCCACCGGGCAGAGCTGCGCAGAGCCCTCTGAGTGTCCAGACTTTGTGGAGGGGCCTGAACCACGGGTGGATTCCCCGGG
CCGGACAGAACCCTGCACCGCCGCCCTGGACCTGGGGGTGCAGCTGACACCCGAGACACTGGTGGAGGCCAAGGAGGAGCCGGTGGAGGT
GCCTGTGGCGGTGCCCGTGGTGGAGGCAGTGCCCGAGGAAGGCCTGGCGCAGGTGGCACCGAGCGAGTCCCAGCCCACCCTAGAAATGTC
AGACTGTGACGTGCCCGCCGGGGAGGGACAGTGCCCGAGCCTGGAGCCCCAAGAGGCCGTGCCTGTACTCGGCAGCACCTGCTTCCTGGA
AGAGGCAAGCTCTGACCAGTTCCTGCCCAGTCTGGAGGACCCACTGGCTGGCATGAACGCCCTGGCGGCAGCTGCGGAGCTGCCCCAGGC
CAGGCCTCTGCCCTCCCCGGGTGCTGCTGGAGCCCAGGCCTTGGAGAAGCTGGAAGCAGCCGAGAGCCTTGTCTTGGAGCAGAGCTTCCT
GCATGGCATCACCCTGCTAAGTGAGATCGCAGAGCTGGAGCTGGAGAGGAGGAGCCAAGAGATGGGAGGAAACCTGTAGGAAGTGTCAGG
GACTCTGGAAAGAACATAATGGCCTCACCTGTGAAGAGCTGGCTGAAAAAGACGACATCAAGTACCGTACCTCTATTGAAGAAAAAATGA
CTGCTGCCCGCATTAGAAAATGCCACAAGTGTGGGACTGGCCTCATCAAATCTGAAGGCTGCAACCGCATGTCTTGCCGCTGTGGTGCCC
AGATGTGCTACCTCTGTCGAGTTTCTATTAATGGATATGACCATTTCTGCCAACATCCCCGCTCACCAGGAGCCCCTTGCCAGGAGTGTT
CAAGATGCTCTCTCTGGACCGATCCCACTGAAGATGATGAGAAGCTTATTGAGGAAATCCAGAAGGAGGCTGAAGAGGAACAGAAAAGAA
AGAATGGAGAGAACACCTTCAAACGCATTGGACCCCCGCTGGAGAAGCCTGTGGAGAAGGTGCAGAGGGTGGAGGCCCTCCCGAGGCCCG
TTCCGCAGAACCTGCCACAGCCACAGATGCCACCCTATGCCTTCGCGCACCCACCCTTCCCCCTGCCTCCCGTGCGGCCTGTGTTCAACA
ACTTCCCACTCAACATGGGGCCTATCCCAGCCCCGTACGTGCCCCCTCTGCCCAACGTGCGGGTCAACTATGACTTCGGTCCCATCCACA
TGCCCCTGGAGCACAACCTGCCCATGCACTTTGGCCCCCAGCCGCGGCATCGCTTCTGATGGCCCCGAATCCCCATTGAGCAGCACAAAG
CCCGTTTGGGGTAGGAGTGTGGATGGAGAACCCTCCCCCAAGGCTGGTGTCTGTACCATTGCATCCTAAGTCAGCTTGAAGGGTAGGCTG
GTTTTCTTCCCACCCCTTTCCTAGAAGGGCTACTGCTCCTGGAAGAGTGGACGGATCCATAATAAAGACGTCCCAAATGGTGGAGTTCGG

>92838_92838_1_TNRC18-RNF216_TNRC18_chr7_5410005_ENST00000399537_RNF216_chr7_5692141_ENST00000389902_length(amino acids)=1417AA_BP=
MIAALPRRMDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGEAFLGSFVASGMGPSASSH
GSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGA
PGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERL
SPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAAT
PAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPA
DAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHH
SRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPE
PAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLVDQERSLS
LSNVKGHGRADEDCVDDRARHREERLLGARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAHLATH
PWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPPLWPALYPPGRSP
LHHAQQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGP
AGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQ
ALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEV
EDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPE
TLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGM

--------------------------------------------------------------
>92838_92838_2_TNRC18-RNF216_TNRC18_chr7_5410005_ENST00000399537_RNF216_chr7_5692141_ENST00000425013_length(transcript)=8092nt_BP=4568nt
GGCCGCGGGATGGCGGGCAGCAGGGGCGCCTAGCTGCGCCGGGAGCCGGGGCCGCCGCCGGAGTCGTTGTCGCCGGAGCCTGGAGCCGTG
AACCCAGCCGCGCCAGACGCCGTGTGCGCCGCCTCGCGCAGCTCCGCCTGGCCGCCCGGAGGGGCCCCACCGCCGGCCGCCTGTGCGCCC
CGGGCCGCGGGCCCGCCGCCGAGCGCAAGCCCCGCTGGCCGCCGCCATGCACGCCGCGGAGCCCCCGCCGCCCGAGGACTCTGGGACTAC
GCCGAGGCCGAACTTTTAGGTCCCACTGAGCTAGGCCTGCGGGCCGGGTGGGGGGCTGATCGCGGCACTCCCGCGGAGGATGGATGGCCG
AGACTTCGGGCCCCAGCGGTCCGTGCACGGTCCCCCGCCGCCGCTGCTGTCCGGCCTGGCCATGGACAGCCACCGCGTGGGCGCGGCCAC
TGCCGGACGCTTGCCCGCCTCGGGCTTGCCCGGCCCGCTGCCGCCCGGGAAGTACATGGCCGGCCTGAATCTCCATCCGCACCCGGGCGA
GGCCTTCTTGGGCAGCTTTGTGGCCAGCGGGATGGGGCCCTCGGCCTCGTCCCATGGGAGCCCAGTGCCACTGCCCTCTGACCTGTCTTT
CCGCTCCCCAACCCCTAGCAACCTGCCCATGGTGCAGCTGTGGGCCGCCCACGCCCATGAAGGCTTCTCCCACCTGCCCAGTGGGCTGTA
CCCATCCTACCTCCACCTGAACCACCTGGAGCCCCCCAGCAGTGGGAGCCCCCTCCTCAGCCAGCTGGGTCAGCCCAGCATTTTCGATAC
CCAGAAAGGTCAGGGGCCAGGAGGAGACGGTTTCTACCTGCCCACCGCGGGGGCTCCGGGCTCCCTGCACTCTCACGCGCCCTCGGCCCG
GACCCCTGGCGGCGGCCACTCCTCGGGCGCCCCGGCCAAAGGCTCGTCGTCGCGGGACGGTCCAGCCAAGGAGCGGGCGGGCCGCGGCGG
GGAGCCGCCTCCGCTTTTCGGCAAGAAGGACCCGCGCGCCCGGGGCGAGGAGGCCTCGGGGCCACGGGGCGTGGTGGACCTGACCCAGGA
GGCGCGCGCCGAGGGCCGCCAGGACCGGGGGCCCCCGCGCCTGGCTGAGCGCCTGTCGCCCTTCCTGGCTGAGTCCAAGACCAAGAATGC
GGCGCTGCAGCCGTCGGTACTGACCATGTGCAACGGCGGCGCCGGGGACGTGGGGCTGCCCGCGCTGGTGGCCGAAGCGGGGCGCGGGGG
TGCCAAGGAGGCTGCCCGGCAGGACGAGGGCGCGCGGCTGCTGCGGCGCACGGAGACCCTGCTCCCTGGGCCGCGCCCCTGCCCCTCACC
GCTGCCCCCGCCGCCCGCGCCCCCCAAGGGGCCTCCTGCACCCCCCGCGGCCACCCCCGCCGGCGTCTACACCGTCTTCCGCGAGCAGGG
CCGTGAGCACCGCGTGGTGGCGCCCACCTTCGTGCCTTCCGTGGAGGCCTTCGACGAGCGCCCGGGGCCCATCCAGATCGCATCCCAGGC
GCGCGATGCCCGGGCCCGCGAGCGCGAGGCTGGCAGGCCAGGGGTCCTGCAGGCGCCCCCCGGCTCCCCGCGGCCTCTGGACCGGCCCGA
GGGCCTGCGCGAGAAGAACTCGGTCATCCGCTCGCTCAAGCGGCCGCCCCCCGCGGATGCCCCCACGGTGCGGGCCACACGCGCCTCCCC
GGACCCCCGCGCCTACGTGCCTGCCAAGGAGCTGCTCAAGCCCGAGGCGGACCCGAGGCCCTGCGAGCGTGCGCCCCGCGGCCCAGCCGG
TCCTGCAGCCCAACAGGCCGCCAAGCTCTTCGGCCTGGAGCCCGGGCGCCCCCCGCCCACCGGCCCTGAGCATAAATGGAAACCCTTCGA
GCTGGGCAACTTCGCCGCCACGCAGATGGCCGTGCTGGCCGCGCAGCACCACCACAGCCGCGCCGAAGAGGAGGCCGCCGTGGTCGCTGC
CTCCTCCTCCAAGAAGGCCTACCTGGACCCTGGGGCTGTGCTGCCCCGCTCGGCGGCCACCTGCGGCCGGCCGGTCGCTGACATGCACTC
TGCGGCCCACGGGTCTGGAGAGGCCTCGGCCATGCAGAGCCTTATAAAGTACAGTGGCAGCTTTGCCCGGGACGCCGTGGCCGTGCGCCC
TGGTGGCTGTGGCAAGAAGAGCCCCTTTGGAGGTTTGGGCACCATGAAACCCGAGCCTGCGCCCACCTCTGCGGGTGCCTCCCGAGCCCA
GGCCCGTCTCCCACACTCCGGAGGCCCTGCAGCGGGCGGCGGCCGGCAGCTGAAGCGGGACCCCGAGAGGCCCGAGAGCGCCAAAGCTTT
CGGGCGCGAGGGCTCTGGTGCCCAGGGTGAGGCAGAAGTGCGACACCCGCCTGTGGGCATTGCAGTGGCTGTGGCCCGGCAGAAGGACAG
TGGCGGCAGTGGCCGGCTGGGGCCTGGGCTGGTAGACCAGGAGCGCTCTCTGTCGCTGAGTAACGTCAAAGGGCACGGCCGAGCAGATGA
GGACTGTGTGGACGACCGGGCCAGACACCGGGAGGAACGGCTGCTCGGGGCACGGCTGGACCGGGATCAGGAGAAGCTGCTCAGAGAGAG
TAAGGAGCTGGCTGACCTGGCCCGCCTGCACCCTACCAGCTGTGCTCCTAACGGCCTGAACCCCAACCTCATGGTGACGGGGGGCCCGGC
GCTGGCGGGCTCAGGTCGCTGGTCTGCCGACCCCGCAGCCCATCTGGCCACGCACCCCTGGTTGCCCCGCTCGGGCAACGCATCCATGTG
GCTCGCTGGACACCCCTACGGCTTGGGTCCCCCATCTCTGCACCAGGGCATGGCCCCTGCGTTCCCACCTGGCCTGGGGGGCTCCCTCCC
GTCAGCCTACCAGTTTGTCAGGGACCCCCAATCGGGCCAGCTGGTGGTCATTCCCAGTGATCACCTTCCTCACTTTGCGGAGCTGATGGA
GCGGGCCACCGTACCGCCCCTCTGGCCCGCCCTGTACCCGCCGGGCCGCAGCCCCCTGCACCACGCCCAGCAGCTGCAGCTCTTCTCACA
GCAGCACTTCCTGCGGCAGCAGGAGTTCCTGTACCTGCAGCAGCAGGCGGCCCAGGCCTTGGAACTGCAGAGGAGCGCCCAGCTCGTGCA
GGAGCGGTTGAAGGCGCAGGAGCACCGGGCGGAGATGGAAGAGAAGGGGAGCAAGCGGGGCCTGGAGGCTGCGGGCAAGGCTGGCCTGGC
CACCGCCGGCCCCGGGCTGCTGCCGCGGAAGCCCCCTGGCCTGGCCGCCGGCCCCGCGGGCACCTACGGCAAGGCCGTGAGCCCGCCACC
ATCACCCCGCGCATCCCCTGTGGCTGCCCTGAAGGCCAAGGTCATCCAGAAGCTGGAGGACGTGTCCAAGCCACCCGCCTACGCCTACCC
CGCCACCCCCAGCTCCCACCCCACCAGCCCGCCGCCCGCCTCCCCACCGCCCACCCCGGGTATCACCCGCAAGGAGGAGGCTCCCGAGAA
TGTGGTCGAGAAGAAAGACTTGGAGTTGGAGAAGGAAGCCCCCAGCCCCTTCCAGGCCCTGTTCTCAGATATCCCGCCCAGGTACCCGTT
CCAAGCCCTGCCACCGCACTACGGGAGGCCCTACCCTTTCCTGCTGCAGCCCACGGCCGCCGCCGACGCGGACGGCTTGGCCCCTGATGT
GCCGCTCCCGGCTGATGGGCCCGAGCGCCTGGCACTCTCACCCGAAGACAAGCCCATCCGCTTGTCCCCCTCCAAGATCACAGAGCCGCT
GCGGGAGGGCCCGGAGGAAGAACCGCTGGCTGAGCGGGAGGTGAAGGCAGAGGTGGAGGACATGGACGAGGGCCCCACAGAGCTGCCGCC
TCTGGAGTCGCCGCTGCCACTGCCCGCCGCGGAAGCCATGGCTACCCCCAGCCCTGCAGGGGGTTGTGGAGGTGGCCTGTTGGAGGCCCA
GGCGCTGAGTGCCACCGGGCAGAGCTGCGCAGAGCCCTCTGAGTGTCCAGACTTTGTGGAGGGGCCTGAACCACGGGTGGATTCCCCGGG
CCGGACAGAACCCTGCACCGCCGCCCTGGACCTGGGGGTGCAGCTGACACCCGAGACACTGGTGGAGGCCAAGGAGGAGCCGGTGGAGGT
GCCTGTGGCGGTGCCCGTGGTGGAGGCAGTGCCCGAGGAAGGCCTGGCGCAGGTGGCACCGAGCGAGTCCCAGCCCACCCTAGAAATGTC
AGACTGTGACGTGCCCGCCGGGGAGGGACAGTGCCCGAGCCTGGAGCCCCAAGAGGCCGTGCCTGTACTCGGCAGCACCTGCTTCCTGGA
AGAGGCAAGCTCTGACCAGTTCCTGCCCAGTCTGGAGGACCCACTGGCTGGCATGAACGCCCTGGCGGCAGCTGCGGAGCTGCCCCAGGC
CAGGCCTCTGCCCTCCCCGGGTGCTGCTGGAGCCCAGGCCTTGGAGAAGCTGGAAGCAGCCGAGAGCCTTGTCTTGGAGCAGAGCTTCCT
GCATGGCATCACCCTGCTAAGTGAGATCGCAGAGCTGGAGCTGGAGAGGAGGAGCCAAGAGATGGGAGGAAACCTGTAGGAAGTGTCAGG
GACTCTGGAAAGAACATAATGGCCTCACCTGTGAAGAGCTGGCTGAAAAAGACGACATCAAGTACCGTACCTCTATTGAAGAAAAAATGA
CTGCTGCCCGCATTAGAAAATGCCACAAGTGTGGGACTGGCCTCATCAAATCTGAAGGCTGCAACCGCATGTCTTGCCGCTGTGGTGCCC
AGATGTGCTACCTCTGTCGAGTTTCTATTAATGGATATGACCATTTCTGCCAACATCCCCGCTCACCAGGAGCCCCTTGCCAGGAGTGTT
CAAGATGCTCTCTCTGGACCGATCCCACTGAAGATGATGAGAAGCTTATTGAGGAAATCCAGAAGGAGGCTGAAGAGGAACAGAAAAGAA
AGAATGGAGAGAACACCTTCAAACGCATTGGACCCCCGCTGGAGAAGCCTGTGGAGAAGGTGCAGAGGGTGGAGGCCCTCCCGAGGCCCG
TTCCGCAGAACCTGCCACAGCCACAGATGCCACCCTATGCCTTCGCGCACCCACCCTTCCCCCTGCCTCCCGTGCGGCCTGTGTTCAACA
ACTTCCCACTCAACATGGGGCCTATCCCAGCCCCGTACGTGCCCCCTCTGCCCAACGTGCGGGTCAACTATGACTTCGGTCCCATCCACA
TGCCCCTGGAGCACAACCTGCCCATGCACTTTGGCCCCCAGCCGCGGCATCGCTTCTGATGGCCCCGAATCCCCATTGAGCAGCACAAAG
CCCGTTTGGGGTAGGAGTGTGGATGGAGAACCCTCCCCCAAGGCTGGTGTCTGTACCATTGCATCCTAAGTCAGCTTGAAGGGTAGGCTG
GTTTTCTTCCCACCCCTTTCCTAGAAGGGCTACTGCTCCTGGAAGAGTGGACGGATCCATAATAAAGACGTCCCAAATGGTGGAGTTCGG
AGAGAGCTGCGATGTGAACTGCCCCTCCCCTCGCATCCCCCAGGCCACCAACGGCAGTCCTTCTGCCTTGTCCATGGCATAGGCCATAGA
CCAGGTCCCTGCTGCTCACACCTGGGCCTCTCCTCGGAGCCGACCCCTGGGTAGCAAGGCAGCCGAGAGCATCTCCCTGGAGGGGCCCAC
GGTTGGGCCAAGGGCAGAGGGGGCTGCACCTGCGGGCCTGGGAAGCATTGCTCAGGGTGGGGGGCTGGGACCATGGCCCGCAGAGGCACT
GCCACAGCTGTGAGGGCCAAGATGCTGTCCCCCCATCCAAAACCCGTGCGCCACTGCAGTGAGTGTTGAGGGCACCTCTCCTCCCCTCTT
ACACCTACTCAGATGAGGCAGCAGCAGACCCATCTCGCGGCGGGGGTTTTGTTCTGTTGCCGCCTAACTTTCTCATCCTCGGTCTCTGGA
AAGTCAGGCTGAGAAATCCTTTCCCAGGCCAGGCCGCTGCGGTACACTGGATGGTTCTGAAGCTGGCCCATTGAAAGAGCCTCTTAAGGC
AGCTGGGACAGAGGCCTGGTGGCCCTGCTGGGCAGCCCAACTGCTGGGGGAGACGTTTCTGCCACCCTGGGTGATGAGCAGCTTTTCCCC
CCTGGCTTTCTGGGGGAGGAGTGGGCCTCCTTAGGGAGACAGGTGACCCTGGGTGCCACCCCTGCCCCGTGTGTGCCCCGGGTGTTCTCA
GTGGTTGCTGAAGGCAGGTAGAGGGTGCTGTCCAGTATCCCCCATGTGAAGGTCACTTCCCTTCTCATGGAGTCAGCTGAGCATCAGCTC
AGCCCTGCCATGTCCCCACTCACCCTCCTCGCCTCCTGTCCGGCCCTGGGTTTCTAGCGGTGCCTGAGGCATCACTCTGGCCCATTGACA
GATGAGAGGTCTGAAGCCTTCCTGGCCACAGGCATCACTTTCTCCTCCTCCTCATGCCCTGCCTTGTCCTTGTCGTGTTGCCATGGGGTT
CTGAGAGGCTGGGAGTTCACAGACCTCAGACACAGCTGAGTCCGACAACCATTGGGGTGGGGCTGCATCAGTCTCCGGAGTGGCCCGCCA
CCTCCTGAAGCAGGGCCTGGCCCACCCAAGGTGCCTGGGGCAGGCGGGCACCGTCATTCGCTGCCATTGGCTTCTCAGATGTATTTCAAG
GACTAAAGTGGGCTCTAAGATCTAAGATGGCCCGGCGCGGTGGCTCCCGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATG
AGTTGAGGTCGGGAGTTTGAGTCCCCGTCTCTACTAAAAATACAAAATTAGCCGGACAAGGTGGCGCATGCCTATAATCCCAGGTACTCA
GGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGAGCAACAA
AAGCAAAACTCTATCTTTAAAAAAAAAAAAAAAAAAACTAAGATACCCATTCTTTCTGCCTTTGCCCAGGATGGAGGCTTTGAAGACAGG
TGGTCACCTGGACCTGGGGTAAGGGTGCGCAGGGAGGCCGGGCTTGGGGGCAGCCTGCTGCTATGTCCTTGCTGGCGCCCATACCTGTTG
GACTGCCTGAACTTTGCTACTAGCCTGAACGACAGTGCCTTGGAAAGGCAGGCTCCATGCGGCAGCAACAGGATTGTCTTCGGTACCTTA
AATATGCTCCCTGTGCTTCCCCAGGGAGGATCTCTGGGAGCAGAGGGCGGCTGTAGACATCACAGCTGAAGAGGTGACCTCAGGCCCTGG
GAGCCTCAGCTCCCTCTGCCCTGTACCCTAGGCACGTGGCTCCAGCAAGAGCCCCAGGCAGGACAAAGGGAGCAGGCAGCAGCTGCAGAA
ACAGCCCTAGACAGGTGCTGGCCTCAACCCTGGCAGGGGAGGGGGAGCCCAGAGTGATGTTTCTCCTAAGGCCAAACCCCAGGGGTGGGT
CATTTGAGAGGAGTTCCAGCTGTTCTGGCCACACTGGGCTGGTGGGGAAGGAGCGGCGGCCTCTTTCCTTGGAGGGTCCCTGATTCCTGA
GGATCCTCCCCGAGCCAGGCACGGGGGACCACAGGGCTGCCGTGAGCACCCACCCTGGTTCTCCAGGCCCCTCTGTCCAGAGGCAGGGCC
TGAACCTCGGGCTCCTGCCTGGACCAGTGACAGCATTGGGGAGAGAAGCACTGGGGGTCTTCAGACCAGCCAGCAAGGGGCCGTGCCAGT
GCCCAGAGAGCAGGTCAGACAACAGGCAACCCTGAGGCAGCTGGCTCCCTCTCTCTGCCCTGCAGGGCTTGCCGCAGGGCGTGAGGCTCC
CCAGCCACAGCCCCCTCTTACTTGCCTTAAAACTGGAGAGAGGAATCTAGTATTTGCACTTAGCAAAATATTTAAAAACTGAAAAAAATG
TGCATGATCTGTCACTTTGTATAAAAACAAGAAACGATTAGTTCATTAAACTTTTTCTTTACCTTCTGGTAGTAAAAATAGATAAAATAA

>92838_92838_2_TNRC18-RNF216_TNRC18_chr7_5410005_ENST00000399537_RNF216_chr7_5692141_ENST00000425013_length(amino acids)=1417AA_BP=
MIAALPRRMDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGEAFLGSFVASGMGPSASSH
GSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGA
PGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERL
SPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAAT
PAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPA
DAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHH
SRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPE
PAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLVDQERSLS
LSNVKGHGRADEDCVDDRARHREERLLGARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAHLATH
PWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPPLWPALYPPGRSP
LHHAQQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGP
AGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQ
ALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEV
EDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPE
TLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGM

--------------------------------------------------------------
>92838_92838_3_TNRC18-RNF216_TNRC18_chr7_5410005_ENST00000430969_RNF216_chr7_5692141_ENST00000389902_length(transcript)=5532nt_BP=4568nt
GGCCGCGGGATGGCGGGCAGCAGGGGCGCCTAGCTGCGCCGGGAGCCGGGGCCGCCGCCGGAGTCGTTGTCGCCGGAGCCTGGAGCCGTG
AACCCAGCCGCGCCAGACGCCGTGTGCGCCGCCTCGCGCAGCTCCGCCTGGCCGCCCGGAGGGGCCCCACCGCCGGCCGCCTGTGCGCCC
CGGGCCGCGGGCCCGCCGCCGAGCGCAAGCCCCGCTGGCCGCCGCCATGCACGCCGCGGAGCCCCCGCCGCCCGAGGACTCTGGGACTAC
GCCGAGGCCGAACTTTTAGGTCCCACTGAGCTAGGCCTGCGGGCCGGGTGGGGGGCTGATCGCGGCACTCCCGCGGAGGATGGATGGCCG
AGACTTCGGGCCCCAGCGGTCCGTGCACGGTCCCCCGCCGCCGCTGCTGTCCGGCCTGGCCATGGACAGCCACCGCGTGGGCGCGGCCAC
TGCCGGACGCTTGCCCGCCTCGGGCTTGCCCGGCCCGCTGCCGCCCGGGAAGTACATGGCCGGCCTGAATCTCCATCCGCACCCGGGCGA
GGCCTTCTTGGGCAGCTTTGTGGCCAGCGGGATGGGGCCCTCGGCCTCGTCCCATGGGAGCCCAGTGCCACTGCCCTCTGACCTGTCTTT
CCGCTCCCCAACCCCTAGCAACCTGCCCATGGTGCAGCTGTGGGCCGCCCACGCCCATGAAGGCTTCTCCCACCTGCCCAGTGGGCTGTA
CCCATCCTACCTCCACCTGAACCACCTGGAGCCCCCCAGCAGTGGGAGCCCCCTCCTCAGCCAGCTGGGTCAGCCCAGCATTTTCGATAC
CCAGAAAGGTCAGGGGCCAGGAGGAGACGGTTTCTACCTGCCCACCGCGGGGGCTCCGGGCTCCCTGCACTCTCACGCGCCCTCGGCCCG
GACCCCTGGCGGCGGCCACTCCTCGGGCGCCCCGGCCAAAGGCTCGTCGTCGCGGGACGGTCCAGCCAAGGAGCGGGCGGGCCGCGGCGG
GGAGCCGCCTCCGCTTTTCGGCAAGAAGGACCCGCGCGCCCGGGGCGAGGAGGCCTCGGGGCCACGGGGCGTGGTGGACCTGACCCAGGA
GGCGCGCGCCGAGGGCCGCCAGGACCGGGGGCCCCCGCGCCTGGCTGAGCGCCTGTCGCCCTTCCTGGCTGAGTCCAAGACCAAGAATGC
GGCGCTGCAGCCGTCGGTACTGACCATGTGCAACGGCGGCGCCGGGGACGTGGGGCTGCCCGCGCTGGTGGCCGAAGCGGGGCGCGGGGG
TGCCAAGGAGGCTGCCCGGCAGGACGAGGGCGCGCGGCTGCTGCGGCGCACGGAGACCCTGCTCCCTGGGCCGCGCCCCTGCCCCTCACC
GCTGCCCCCGCCGCCCGCGCCCCCCAAGGGGCCTCCTGCACCCCCCGCGGCCACCCCCGCCGGCGTCTACACCGTCTTCCGCGAGCAGGG
CCGTGAGCACCGCGTGGTGGCGCCCACCTTCGTGCCTTCCGTGGAGGCCTTCGACGAGCGCCCGGGGCCCATCCAGATCGCATCCCAGGC
GCGCGATGCCCGGGCCCGCGAGCGCGAGGCTGGCAGGCCAGGGGTCCTGCAGGCGCCCCCCGGCTCCCCGCGGCCTCTGGACCGGCCCGA
GGGCCTGCGCGAGAAGAACTCGGTCATCCGCTCGCTCAAGCGGCCGCCCCCCGCGGATGCCCCCACGGTGCGGGCCACACGCGCCTCCCC
GGACCCCCGCGCCTACGTGCCTGCCAAGGAGCTGCTCAAGCCCGAGGCGGACCCGAGGCCCTGCGAGCGTGCGCCCCGCGGCCCAGCCGG
TCCTGCAGCCCAACAGGCCGCCAAGCTCTTCGGCCTGGAGCCCGGGCGCCCCCCGCCCACCGGCCCTGAGCATAAATGGAAACCCTTCGA
GCTGGGCAACTTCGCCGCCACGCAGATGGCCGTGCTGGCCGCGCAGCACCACCACAGCCGCGCCGAAGAGGAGGCCGCCGTGGTCGCTGC
CTCCTCCTCCAAGAAGGCCTACCTGGACCCTGGGGCTGTGCTGCCCCGCTCGGCGGCCACCTGCGGCCGGCCGGTCGCTGACATGCACTC
TGCGGCCCACGGGTCTGGAGAGGCCTCGGCCATGCAGAGCCTTATAAAGTACAGTGGCAGCTTTGCCCGGGACGCCGTGGCCGTGCGCCC
TGGTGGCTGTGGCAAGAAGAGCCCCTTTGGAGGTTTGGGCACCATGAAACCCGAGCCTGCGCCCACCTCTGCGGGTGCCTCCCGAGCCCA
GGCCCGTCTCCCACACTCCGGAGGCCCTGCAGCGGGCGGCGGCCGGCAGCTGAAGCGGGACCCCGAGAGGCCCGAGAGCGCCAAAGCTTT
CGGGCGCGAGGGCTCTGGTGCCCAGGGTGAGGCAGAAGTGCGACACCCGCCTGTGGGCATTGCAGTGGCTGTGGCCCGGCAGAAGGACAG
TGGCGGCAGTGGCCGGCTGGGGCCTGGGCTGGTAGACCAGGAGCGCTCTCTGTCGCTGAGTAACGTCAAAGGGCACGGCCGAGCAGATGA
GGACTGTGTGGACGACCGGGCCAGACACCGGGAGGAACGGCTGCTCGGGGCACGGCTGGACCGGGATCAGGAGAAGCTGCTCAGAGAGAG
TAAGGAGCTGGCTGACCTGGCCCGCCTGCACCCTACCAGCTGTGCTCCTAACGGCCTGAACCCCAACCTCATGGTGACGGGGGGCCCGGC
GCTGGCGGGCTCAGGTCGCTGGTCTGCCGACCCCGCAGCCCATCTGGCCACGCACCCCTGGTTGCCCCGCTCGGGCAACGCATCCATGTG
GCTCGCTGGACACCCCTACGGCTTGGGTCCCCCATCTCTGCACCAGGGCATGGCCCCTGCGTTCCCACCTGGCCTGGGGGGCTCCCTCCC
GTCAGCCTACCAGTTTGTCAGGGACCCCCAATCGGGCCAGCTGGTGGTCATTCCCAGTGATCACCTTCCTCACTTTGCGGAGCTGATGGA
GCGGGCCACCGTACCGCCCCTCTGGCCCGCCCTGTACCCGCCGGGCCGCAGCCCCCTGCACCACGCCCAGCAGCTGCAGCTCTTCTCACA
GCAGCACTTCCTGCGGCAGCAGGAGTTCCTGTACCTGCAGCAGCAGGCGGCCCAGGCCTTGGAACTGCAGAGGAGCGCCCAGCTCGTGCA
GGAGCGGTTGAAGGCGCAGGAGCACCGGGCGGAGATGGAAGAGAAGGGGAGCAAGCGGGGCCTGGAGGCTGCGGGCAAGGCTGGCCTGGC
CACCGCCGGCCCCGGGCTGCTGCCGCGGAAGCCCCCTGGCCTGGCCGCCGGCCCCGCGGGCACCTACGGCAAGGCCGTGAGCCCGCCACC
ATCACCCCGCGCATCCCCTGTGGCTGCCCTGAAGGCCAAGGTCATCCAGAAGCTGGAGGACGTGTCCAAGCCACCCGCCTACGCCTACCC
CGCCACCCCCAGCTCCCACCCCACCAGCCCGCCGCCCGCCTCCCCACCGCCCACCCCGGGTATCACCCGCAAGGAGGAGGCTCCCGAGAA
TGTGGTCGAGAAGAAAGACTTGGAGTTGGAGAAGGAAGCCCCCAGCCCCTTCCAGGCCCTGTTCTCAGATATCCCGCCCAGGTACCCGTT
CCAAGCCCTGCCACCGCACTACGGGAGGCCCTACCCTTTCCTGCTGCAGCCCACGGCCGCCGCCGACGCGGACGGCTTGGCCCCTGATGT
GCCGCTCCCGGCTGATGGGCCCGAGCGCCTGGCACTCTCACCCGAAGACAAGCCCATCCGCTTGTCCCCCTCCAAGATCACAGAGCCGCT
GCGGGAGGGCCCGGAGGAAGAACCGCTGGCTGAGCGGGAGGTGAAGGCAGAGGTGGAGGACATGGACGAGGGCCCCACAGAGCTGCCGCC
TCTGGAGTCGCCGCTGCCACTGCCCGCCGCGGAAGCCATGGCTACCCCCAGCCCTGCAGGGGGTTGTGGAGGTGGCCTGTTGGAGGCCCA
GGCGCTGAGTGCCACCGGGCAGAGCTGCGCAGAGCCCTCTGAGTGTCCAGACTTTGTGGAGGGGCCTGAACCACGGGTGGATTCCCCGGG
CCGGACAGAACCCTGCACCGCCGCCCTGGACCTGGGGGTGCAGCTGACACCCGAGACACTGGTGGAGGCCAAGGAGGAGCCGGTGGAGGT
GCCTGTGGCGGTGCCCGTGGTGGAGGCAGTGCCCGAGGAAGGCCTGGCGCAGGTGGCACCGAGCGAGTCCCAGCCCACCCTAGAAATGTC
AGACTGTGACGTGCCCGCCGGGGAGGGACAGTGCCCGAGCCTGGAGCCCCAAGAGGCCGTGCCTGTACTCGGCAGCACCTGCTTCCTGGA
AGAGGCAAGCTCTGACCAGTTCCTGCCCAGTCTGGAGGACCCACTGGCTGGCATGAACGCCCTGGCGGCAGCTGCGGAGCTGCCCCAGGC
CAGGCCTCTGCCCTCCCCGGGTGCTGCTGGAGCCCAGGCCTTGGAGAAGCTGGAAGCAGCCGAGAGCCTTGTCTTGGAGCAGAGCTTCCT
GCATGGCATCACCCTGCTAAGTGAGATCGCAGAGCTGGAGCTGGAGAGGAGGAGCCAAGAGATGGGAGGAAACCTGTAGGAAGTGTCAGG
GACTCTGGAAAGAACATAATGGCCTCACCTGTGAAGAGCTGGCTGAAAAAGACGACATCAAGTACCGTACCTCTATTGAAGAAAAAATGA
CTGCTGCCCGCATTAGAAAATGCCACAAGTGTGGGACTGGCCTCATCAAATCTGAAGGCTGCAACCGCATGTCTTGCCGCTGTGGTGCCC
AGATGTGCTACCTCTGTCGAGTTTCTATTAATGGATATGACCATTTCTGCCAACATCCCCGCTCACCAGGAGCCCCTTGCCAGGAGTGTT
CAAGATGCTCTCTCTGGACCGATCCCACTGAAGATGATGAGAAGCTTATTGAGGAAATCCAGAAGGAGGCTGAAGAGGAACAGAAAAGAA
AGAATGGAGAGAACACCTTCAAACGCATTGGACCCCCGCTGGAGAAGCCTGTGGAGAAGGTGCAGAGGGTGGAGGCCCTCCCGAGGCCCG
TTCCGCAGAACCTGCCACAGCCACAGATGCCACCCTATGCCTTCGCGCACCCACCCTTCCCCCTGCCTCCCGTGCGGCCTGTGTTCAACA
ACTTCCCACTCAACATGGGGCCTATCCCAGCCCCGTACGTGCCCCCTCTGCCCAACGTGCGGGTCAACTATGACTTCGGTCCCATCCACA
TGCCCCTGGAGCACAACCTGCCCATGCACTTTGGCCCCCAGCCGCGGCATCGCTTCTGATGGCCCCGAATCCCCATTGAGCAGCACAAAG
CCCGTTTGGGGTAGGAGTGTGGATGGAGAACCCTCCCCCAAGGCTGGTGTCTGTACCATTGCATCCTAAGTCAGCTTGAAGGGTAGGCTG
GTTTTCTTCCCACCCCTTTCCTAGAAGGGCTACTGCTCCTGGAAGAGTGGACGGATCCATAATAAAGACGTCCCAAATGGTGGAGTTCGG

>92838_92838_3_TNRC18-RNF216_TNRC18_chr7_5410005_ENST00000430969_RNF216_chr7_5692141_ENST00000389902_length(amino acids)=1417AA_BP=
MIAALPRRMDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGEAFLGSFVASGMGPSASSH
GSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGA
PGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERL
SPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAAT
PAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPA
DAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHH
SRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPE
PAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLVDQERSLS
LSNVKGHGRADEDCVDDRARHREERLLGARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAHLATH
PWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPPLWPALYPPGRSP
LHHAQQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGP
AGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQ
ALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEV
EDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPE
TLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGM

--------------------------------------------------------------
>92838_92838_4_TNRC18-RNF216_TNRC18_chr7_5410005_ENST00000430969_RNF216_chr7_5692141_ENST00000425013_length(transcript)=8092nt_BP=4568nt
GGCCGCGGGATGGCGGGCAGCAGGGGCGCCTAGCTGCGCCGGGAGCCGGGGCCGCCGCCGGAGTCGTTGTCGCCGGAGCCTGGAGCCGTG
AACCCAGCCGCGCCAGACGCCGTGTGCGCCGCCTCGCGCAGCTCCGCCTGGCCGCCCGGAGGGGCCCCACCGCCGGCCGCCTGTGCGCCC
CGGGCCGCGGGCCCGCCGCCGAGCGCAAGCCCCGCTGGCCGCCGCCATGCACGCCGCGGAGCCCCCGCCGCCCGAGGACTCTGGGACTAC
GCCGAGGCCGAACTTTTAGGTCCCACTGAGCTAGGCCTGCGGGCCGGGTGGGGGGCTGATCGCGGCACTCCCGCGGAGGATGGATGGCCG
AGACTTCGGGCCCCAGCGGTCCGTGCACGGTCCCCCGCCGCCGCTGCTGTCCGGCCTGGCCATGGACAGCCACCGCGTGGGCGCGGCCAC
TGCCGGACGCTTGCCCGCCTCGGGCTTGCCCGGCCCGCTGCCGCCCGGGAAGTACATGGCCGGCCTGAATCTCCATCCGCACCCGGGCGA
GGCCTTCTTGGGCAGCTTTGTGGCCAGCGGGATGGGGCCCTCGGCCTCGTCCCATGGGAGCCCAGTGCCACTGCCCTCTGACCTGTCTTT
CCGCTCCCCAACCCCTAGCAACCTGCCCATGGTGCAGCTGTGGGCCGCCCACGCCCATGAAGGCTTCTCCCACCTGCCCAGTGGGCTGTA
CCCATCCTACCTCCACCTGAACCACCTGGAGCCCCCCAGCAGTGGGAGCCCCCTCCTCAGCCAGCTGGGTCAGCCCAGCATTTTCGATAC
CCAGAAAGGTCAGGGGCCAGGAGGAGACGGTTTCTACCTGCCCACCGCGGGGGCTCCGGGCTCCCTGCACTCTCACGCGCCCTCGGCCCG
GACCCCTGGCGGCGGCCACTCCTCGGGCGCCCCGGCCAAAGGCTCGTCGTCGCGGGACGGTCCAGCCAAGGAGCGGGCGGGCCGCGGCGG
GGAGCCGCCTCCGCTTTTCGGCAAGAAGGACCCGCGCGCCCGGGGCGAGGAGGCCTCGGGGCCACGGGGCGTGGTGGACCTGACCCAGGA
GGCGCGCGCCGAGGGCCGCCAGGACCGGGGGCCCCCGCGCCTGGCTGAGCGCCTGTCGCCCTTCCTGGCTGAGTCCAAGACCAAGAATGC
GGCGCTGCAGCCGTCGGTACTGACCATGTGCAACGGCGGCGCCGGGGACGTGGGGCTGCCCGCGCTGGTGGCCGAAGCGGGGCGCGGGGG
TGCCAAGGAGGCTGCCCGGCAGGACGAGGGCGCGCGGCTGCTGCGGCGCACGGAGACCCTGCTCCCTGGGCCGCGCCCCTGCCCCTCACC
GCTGCCCCCGCCGCCCGCGCCCCCCAAGGGGCCTCCTGCACCCCCCGCGGCCACCCCCGCCGGCGTCTACACCGTCTTCCGCGAGCAGGG
CCGTGAGCACCGCGTGGTGGCGCCCACCTTCGTGCCTTCCGTGGAGGCCTTCGACGAGCGCCCGGGGCCCATCCAGATCGCATCCCAGGC
GCGCGATGCCCGGGCCCGCGAGCGCGAGGCTGGCAGGCCAGGGGTCCTGCAGGCGCCCCCCGGCTCCCCGCGGCCTCTGGACCGGCCCGA
GGGCCTGCGCGAGAAGAACTCGGTCATCCGCTCGCTCAAGCGGCCGCCCCCCGCGGATGCCCCCACGGTGCGGGCCACACGCGCCTCCCC
GGACCCCCGCGCCTACGTGCCTGCCAAGGAGCTGCTCAAGCCCGAGGCGGACCCGAGGCCCTGCGAGCGTGCGCCCCGCGGCCCAGCCGG
TCCTGCAGCCCAACAGGCCGCCAAGCTCTTCGGCCTGGAGCCCGGGCGCCCCCCGCCCACCGGCCCTGAGCATAAATGGAAACCCTTCGA
GCTGGGCAACTTCGCCGCCACGCAGATGGCCGTGCTGGCCGCGCAGCACCACCACAGCCGCGCCGAAGAGGAGGCCGCCGTGGTCGCTGC
CTCCTCCTCCAAGAAGGCCTACCTGGACCCTGGGGCTGTGCTGCCCCGCTCGGCGGCCACCTGCGGCCGGCCGGTCGCTGACATGCACTC
TGCGGCCCACGGGTCTGGAGAGGCCTCGGCCATGCAGAGCCTTATAAAGTACAGTGGCAGCTTTGCCCGGGACGCCGTGGCCGTGCGCCC
TGGTGGCTGTGGCAAGAAGAGCCCCTTTGGAGGTTTGGGCACCATGAAACCCGAGCCTGCGCCCACCTCTGCGGGTGCCTCCCGAGCCCA
GGCCCGTCTCCCACACTCCGGAGGCCCTGCAGCGGGCGGCGGCCGGCAGCTGAAGCGGGACCCCGAGAGGCCCGAGAGCGCCAAAGCTTT
CGGGCGCGAGGGCTCTGGTGCCCAGGGTGAGGCAGAAGTGCGACACCCGCCTGTGGGCATTGCAGTGGCTGTGGCCCGGCAGAAGGACAG
TGGCGGCAGTGGCCGGCTGGGGCCTGGGCTGGTAGACCAGGAGCGCTCTCTGTCGCTGAGTAACGTCAAAGGGCACGGCCGAGCAGATGA
GGACTGTGTGGACGACCGGGCCAGACACCGGGAGGAACGGCTGCTCGGGGCACGGCTGGACCGGGATCAGGAGAAGCTGCTCAGAGAGAG
TAAGGAGCTGGCTGACCTGGCCCGCCTGCACCCTACCAGCTGTGCTCCTAACGGCCTGAACCCCAACCTCATGGTGACGGGGGGCCCGGC
GCTGGCGGGCTCAGGTCGCTGGTCTGCCGACCCCGCAGCCCATCTGGCCACGCACCCCTGGTTGCCCCGCTCGGGCAACGCATCCATGTG
GCTCGCTGGACACCCCTACGGCTTGGGTCCCCCATCTCTGCACCAGGGCATGGCCCCTGCGTTCCCACCTGGCCTGGGGGGCTCCCTCCC
GTCAGCCTACCAGTTTGTCAGGGACCCCCAATCGGGCCAGCTGGTGGTCATTCCCAGTGATCACCTTCCTCACTTTGCGGAGCTGATGGA
GCGGGCCACCGTACCGCCCCTCTGGCCCGCCCTGTACCCGCCGGGCCGCAGCCCCCTGCACCACGCCCAGCAGCTGCAGCTCTTCTCACA
GCAGCACTTCCTGCGGCAGCAGGAGTTCCTGTACCTGCAGCAGCAGGCGGCCCAGGCCTTGGAACTGCAGAGGAGCGCCCAGCTCGTGCA
GGAGCGGTTGAAGGCGCAGGAGCACCGGGCGGAGATGGAAGAGAAGGGGAGCAAGCGGGGCCTGGAGGCTGCGGGCAAGGCTGGCCTGGC
CACCGCCGGCCCCGGGCTGCTGCCGCGGAAGCCCCCTGGCCTGGCCGCCGGCCCCGCGGGCACCTACGGCAAGGCCGTGAGCCCGCCACC
ATCACCCCGCGCATCCCCTGTGGCTGCCCTGAAGGCCAAGGTCATCCAGAAGCTGGAGGACGTGTCCAAGCCACCCGCCTACGCCTACCC
CGCCACCCCCAGCTCCCACCCCACCAGCCCGCCGCCCGCCTCCCCACCGCCCACCCCGGGTATCACCCGCAAGGAGGAGGCTCCCGAGAA
TGTGGTCGAGAAGAAAGACTTGGAGTTGGAGAAGGAAGCCCCCAGCCCCTTCCAGGCCCTGTTCTCAGATATCCCGCCCAGGTACCCGTT
CCAAGCCCTGCCACCGCACTACGGGAGGCCCTACCCTTTCCTGCTGCAGCCCACGGCCGCCGCCGACGCGGACGGCTTGGCCCCTGATGT
GCCGCTCCCGGCTGATGGGCCCGAGCGCCTGGCACTCTCACCCGAAGACAAGCCCATCCGCTTGTCCCCCTCCAAGATCACAGAGCCGCT
GCGGGAGGGCCCGGAGGAAGAACCGCTGGCTGAGCGGGAGGTGAAGGCAGAGGTGGAGGACATGGACGAGGGCCCCACAGAGCTGCCGCC
TCTGGAGTCGCCGCTGCCACTGCCCGCCGCGGAAGCCATGGCTACCCCCAGCCCTGCAGGGGGTTGTGGAGGTGGCCTGTTGGAGGCCCA
GGCGCTGAGTGCCACCGGGCAGAGCTGCGCAGAGCCCTCTGAGTGTCCAGACTTTGTGGAGGGGCCTGAACCACGGGTGGATTCCCCGGG
CCGGACAGAACCCTGCACCGCCGCCCTGGACCTGGGGGTGCAGCTGACACCCGAGACACTGGTGGAGGCCAAGGAGGAGCCGGTGGAGGT
GCCTGTGGCGGTGCCCGTGGTGGAGGCAGTGCCCGAGGAAGGCCTGGCGCAGGTGGCACCGAGCGAGTCCCAGCCCACCCTAGAAATGTC
AGACTGTGACGTGCCCGCCGGGGAGGGACAGTGCCCGAGCCTGGAGCCCCAAGAGGCCGTGCCTGTACTCGGCAGCACCTGCTTCCTGGA
AGAGGCAAGCTCTGACCAGTTCCTGCCCAGTCTGGAGGACCCACTGGCTGGCATGAACGCCCTGGCGGCAGCTGCGGAGCTGCCCCAGGC
CAGGCCTCTGCCCTCCCCGGGTGCTGCTGGAGCCCAGGCCTTGGAGAAGCTGGAAGCAGCCGAGAGCCTTGTCTTGGAGCAGAGCTTCCT
GCATGGCATCACCCTGCTAAGTGAGATCGCAGAGCTGGAGCTGGAGAGGAGGAGCCAAGAGATGGGAGGAAACCTGTAGGAAGTGTCAGG
GACTCTGGAAAGAACATAATGGCCTCACCTGTGAAGAGCTGGCTGAAAAAGACGACATCAAGTACCGTACCTCTATTGAAGAAAAAATGA
CTGCTGCCCGCATTAGAAAATGCCACAAGTGTGGGACTGGCCTCATCAAATCTGAAGGCTGCAACCGCATGTCTTGCCGCTGTGGTGCCC
AGATGTGCTACCTCTGTCGAGTTTCTATTAATGGATATGACCATTTCTGCCAACATCCCCGCTCACCAGGAGCCCCTTGCCAGGAGTGTT
CAAGATGCTCTCTCTGGACCGATCCCACTGAAGATGATGAGAAGCTTATTGAGGAAATCCAGAAGGAGGCTGAAGAGGAACAGAAAAGAA
AGAATGGAGAGAACACCTTCAAACGCATTGGACCCCCGCTGGAGAAGCCTGTGGAGAAGGTGCAGAGGGTGGAGGCCCTCCCGAGGCCCG
TTCCGCAGAACCTGCCACAGCCACAGATGCCACCCTATGCCTTCGCGCACCCACCCTTCCCCCTGCCTCCCGTGCGGCCTGTGTTCAACA
ACTTCCCACTCAACATGGGGCCTATCCCAGCCCCGTACGTGCCCCCTCTGCCCAACGTGCGGGTCAACTATGACTTCGGTCCCATCCACA
TGCCCCTGGAGCACAACCTGCCCATGCACTTTGGCCCCCAGCCGCGGCATCGCTTCTGATGGCCCCGAATCCCCATTGAGCAGCACAAAG
CCCGTTTGGGGTAGGAGTGTGGATGGAGAACCCTCCCCCAAGGCTGGTGTCTGTACCATTGCATCCTAAGTCAGCTTGAAGGGTAGGCTG
GTTTTCTTCCCACCCCTTTCCTAGAAGGGCTACTGCTCCTGGAAGAGTGGACGGATCCATAATAAAGACGTCCCAAATGGTGGAGTTCGG
AGAGAGCTGCGATGTGAACTGCCCCTCCCCTCGCATCCCCCAGGCCACCAACGGCAGTCCTTCTGCCTTGTCCATGGCATAGGCCATAGA
CCAGGTCCCTGCTGCTCACACCTGGGCCTCTCCTCGGAGCCGACCCCTGGGTAGCAAGGCAGCCGAGAGCATCTCCCTGGAGGGGCCCAC
GGTTGGGCCAAGGGCAGAGGGGGCTGCACCTGCGGGCCTGGGAAGCATTGCTCAGGGTGGGGGGCTGGGACCATGGCCCGCAGAGGCACT
GCCACAGCTGTGAGGGCCAAGATGCTGTCCCCCCATCCAAAACCCGTGCGCCACTGCAGTGAGTGTTGAGGGCACCTCTCCTCCCCTCTT
ACACCTACTCAGATGAGGCAGCAGCAGACCCATCTCGCGGCGGGGGTTTTGTTCTGTTGCCGCCTAACTTTCTCATCCTCGGTCTCTGGA
AAGTCAGGCTGAGAAATCCTTTCCCAGGCCAGGCCGCTGCGGTACACTGGATGGTTCTGAAGCTGGCCCATTGAAAGAGCCTCTTAAGGC
AGCTGGGACAGAGGCCTGGTGGCCCTGCTGGGCAGCCCAACTGCTGGGGGAGACGTTTCTGCCACCCTGGGTGATGAGCAGCTTTTCCCC
CCTGGCTTTCTGGGGGAGGAGTGGGCCTCCTTAGGGAGACAGGTGACCCTGGGTGCCACCCCTGCCCCGTGTGTGCCCCGGGTGTTCTCA
GTGGTTGCTGAAGGCAGGTAGAGGGTGCTGTCCAGTATCCCCCATGTGAAGGTCACTTCCCTTCTCATGGAGTCAGCTGAGCATCAGCTC
AGCCCTGCCATGTCCCCACTCACCCTCCTCGCCTCCTGTCCGGCCCTGGGTTTCTAGCGGTGCCTGAGGCATCACTCTGGCCCATTGACA
GATGAGAGGTCTGAAGCCTTCCTGGCCACAGGCATCACTTTCTCCTCCTCCTCATGCCCTGCCTTGTCCTTGTCGTGTTGCCATGGGGTT
CTGAGAGGCTGGGAGTTCACAGACCTCAGACACAGCTGAGTCCGACAACCATTGGGGTGGGGCTGCATCAGTCTCCGGAGTGGCCCGCCA
CCTCCTGAAGCAGGGCCTGGCCCACCCAAGGTGCCTGGGGCAGGCGGGCACCGTCATTCGCTGCCATTGGCTTCTCAGATGTATTTCAAG
GACTAAAGTGGGCTCTAAGATCTAAGATGGCCCGGCGCGGTGGCTCCCGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATG
AGTTGAGGTCGGGAGTTTGAGTCCCCGTCTCTACTAAAAATACAAAATTAGCCGGACAAGGTGGCGCATGCCTATAATCCCAGGTACTCA
GGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGAGCAACAA
AAGCAAAACTCTATCTTTAAAAAAAAAAAAAAAAAAACTAAGATACCCATTCTTTCTGCCTTTGCCCAGGATGGAGGCTTTGAAGACAGG
TGGTCACCTGGACCTGGGGTAAGGGTGCGCAGGGAGGCCGGGCTTGGGGGCAGCCTGCTGCTATGTCCTTGCTGGCGCCCATACCTGTTG
GACTGCCTGAACTTTGCTACTAGCCTGAACGACAGTGCCTTGGAAAGGCAGGCTCCATGCGGCAGCAACAGGATTGTCTTCGGTACCTTA
AATATGCTCCCTGTGCTTCCCCAGGGAGGATCTCTGGGAGCAGAGGGCGGCTGTAGACATCACAGCTGAAGAGGTGACCTCAGGCCCTGG
GAGCCTCAGCTCCCTCTGCCCTGTACCCTAGGCACGTGGCTCCAGCAAGAGCCCCAGGCAGGACAAAGGGAGCAGGCAGCAGCTGCAGAA
ACAGCCCTAGACAGGTGCTGGCCTCAACCCTGGCAGGGGAGGGGGAGCCCAGAGTGATGTTTCTCCTAAGGCCAAACCCCAGGGGTGGGT
CATTTGAGAGGAGTTCCAGCTGTTCTGGCCACACTGGGCTGGTGGGGAAGGAGCGGCGGCCTCTTTCCTTGGAGGGTCCCTGATTCCTGA
GGATCCTCCCCGAGCCAGGCACGGGGGACCACAGGGCTGCCGTGAGCACCCACCCTGGTTCTCCAGGCCCCTCTGTCCAGAGGCAGGGCC
TGAACCTCGGGCTCCTGCCTGGACCAGTGACAGCATTGGGGAGAGAAGCACTGGGGGTCTTCAGACCAGCCAGCAAGGGGCCGTGCCAGT
GCCCAGAGAGCAGGTCAGACAACAGGCAACCCTGAGGCAGCTGGCTCCCTCTCTCTGCCCTGCAGGGCTTGCCGCAGGGCGTGAGGCTCC
CCAGCCACAGCCCCCTCTTACTTGCCTTAAAACTGGAGAGAGGAATCTAGTATTTGCACTTAGCAAAATATTTAAAAACTGAAAAAAATG
TGCATGATCTGTCACTTTGTATAAAAACAAGAAACGATTAGTTCATTAAACTTTTTCTTTACCTTCTGGTAGTAAAAATAGATAAAATAA

>92838_92838_4_TNRC18-RNF216_TNRC18_chr7_5410005_ENST00000430969_RNF216_chr7_5692141_ENST00000425013_length(amino acids)=1417AA_BP=
MIAALPRRMDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGEAFLGSFVASGMGPSASSH
GSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGA
PGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERL
SPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAAT
PAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPA
DAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHH
SRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPE
PAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLVDQERSLS
LSNVKGHGRADEDCVDDRARHREERLLGARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAHLATH
PWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPPLWPALYPPGRSP
LHHAQQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGP
AGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQ
ALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEV
EDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPE
TLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGM

--------------------------------------------------------------
>92838_92838_5_TNRC18-RNF216_TNRC18_chr7_5410006_ENST00000399537_RNF216_chr7_5692141_ENST00000389902_length(transcript)=5532nt_BP=4568nt
GGCCGCGGGATGGCGGGCAGCAGGGGCGCCTAGCTGCGCCGGGAGCCGGGGCCGCCGCCGGAGTCGTTGTCGCCGGAGCCTGGAGCCGTG
AACCCAGCCGCGCCAGACGCCGTGTGCGCCGCCTCGCGCAGCTCCGCCTGGCCGCCCGGAGGGGCCCCACCGCCGGCCGCCTGTGCGCCC
CGGGCCGCGGGCCCGCCGCCGAGCGCAAGCCCCGCTGGCCGCCGCCATGCACGCCGCGGAGCCCCCGCCGCCCGAGGACTCTGGGACTAC
GCCGAGGCCGAACTTTTAGGTCCCACTGAGCTAGGCCTGCGGGCCGGGTGGGGGGCTGATCGCGGCACTCCCGCGGAGGATGGATGGCCG
AGACTTCGGGCCCCAGCGGTCCGTGCACGGTCCCCCGCCGCCGCTGCTGTCCGGCCTGGCCATGGACAGCCACCGCGTGGGCGCGGCCAC
TGCCGGACGCTTGCCCGCCTCGGGCTTGCCCGGCCCGCTGCCGCCCGGGAAGTACATGGCCGGCCTGAATCTCCATCCGCACCCGGGCGA
GGCCTTCTTGGGCAGCTTTGTGGCCAGCGGGATGGGGCCCTCGGCCTCGTCCCATGGGAGCCCAGTGCCACTGCCCTCTGACCTGTCTTT
CCGCTCCCCAACCCCTAGCAACCTGCCCATGGTGCAGCTGTGGGCCGCCCACGCCCATGAAGGCTTCTCCCACCTGCCCAGTGGGCTGTA
CCCATCCTACCTCCACCTGAACCACCTGGAGCCCCCCAGCAGTGGGAGCCCCCTCCTCAGCCAGCTGGGTCAGCCCAGCATTTTCGATAC
CCAGAAAGGTCAGGGGCCAGGAGGAGACGGTTTCTACCTGCCCACCGCGGGGGCTCCGGGCTCCCTGCACTCTCACGCGCCCTCGGCCCG
GACCCCTGGCGGCGGCCACTCCTCGGGCGCCCCGGCCAAAGGCTCGTCGTCGCGGGACGGTCCAGCCAAGGAGCGGGCGGGCCGCGGCGG
GGAGCCGCCTCCGCTTTTCGGCAAGAAGGACCCGCGCGCCCGGGGCGAGGAGGCCTCGGGGCCACGGGGCGTGGTGGACCTGACCCAGGA
GGCGCGCGCCGAGGGCCGCCAGGACCGGGGGCCCCCGCGCCTGGCTGAGCGCCTGTCGCCCTTCCTGGCTGAGTCCAAGACCAAGAATGC
GGCGCTGCAGCCGTCGGTACTGACCATGTGCAACGGCGGCGCCGGGGACGTGGGGCTGCCCGCGCTGGTGGCCGAAGCGGGGCGCGGGGG
TGCCAAGGAGGCTGCCCGGCAGGACGAGGGCGCGCGGCTGCTGCGGCGCACGGAGACCCTGCTCCCTGGGCCGCGCCCCTGCCCCTCACC
GCTGCCCCCGCCGCCCGCGCCCCCCAAGGGGCCTCCTGCACCCCCCGCGGCCACCCCCGCCGGCGTCTACACCGTCTTCCGCGAGCAGGG
CCGTGAGCACCGCGTGGTGGCGCCCACCTTCGTGCCTTCCGTGGAGGCCTTCGACGAGCGCCCGGGGCCCATCCAGATCGCATCCCAGGC
GCGCGATGCCCGGGCCCGCGAGCGCGAGGCTGGCAGGCCAGGGGTCCTGCAGGCGCCCCCCGGCTCCCCGCGGCCTCTGGACCGGCCCGA
GGGCCTGCGCGAGAAGAACTCGGTCATCCGCTCGCTCAAGCGGCCGCCCCCCGCGGATGCCCCCACGGTGCGGGCCACACGCGCCTCCCC
GGACCCCCGCGCCTACGTGCCTGCCAAGGAGCTGCTCAAGCCCGAGGCGGACCCGAGGCCCTGCGAGCGTGCGCCCCGCGGCCCAGCCGG
TCCTGCAGCCCAACAGGCCGCCAAGCTCTTCGGCCTGGAGCCCGGGCGCCCCCCGCCCACCGGCCCTGAGCATAAATGGAAACCCTTCGA
GCTGGGCAACTTCGCCGCCACGCAGATGGCCGTGCTGGCCGCGCAGCACCACCACAGCCGCGCCGAAGAGGAGGCCGCCGTGGTCGCTGC
CTCCTCCTCCAAGAAGGCCTACCTGGACCCTGGGGCTGTGCTGCCCCGCTCGGCGGCCACCTGCGGCCGGCCGGTCGCTGACATGCACTC
TGCGGCCCACGGGTCTGGAGAGGCCTCGGCCATGCAGAGCCTTATAAAGTACAGTGGCAGCTTTGCCCGGGACGCCGTGGCCGTGCGCCC
TGGTGGCTGTGGCAAGAAGAGCCCCTTTGGAGGTTTGGGCACCATGAAACCCGAGCCTGCGCCCACCTCTGCGGGTGCCTCCCGAGCCCA
GGCCCGTCTCCCACACTCCGGAGGCCCTGCAGCGGGCGGCGGCCGGCAGCTGAAGCGGGACCCCGAGAGGCCCGAGAGCGCCAAAGCTTT
CGGGCGCGAGGGCTCTGGTGCCCAGGGTGAGGCAGAAGTGCGACACCCGCCTGTGGGCATTGCAGTGGCTGTGGCCCGGCAGAAGGACAG
TGGCGGCAGTGGCCGGCTGGGGCCTGGGCTGGTAGACCAGGAGCGCTCTCTGTCGCTGAGTAACGTCAAAGGGCACGGCCGAGCAGATGA
GGACTGTGTGGACGACCGGGCCAGACACCGGGAGGAACGGCTGCTCGGGGCACGGCTGGACCGGGATCAGGAGAAGCTGCTCAGAGAGAG
TAAGGAGCTGGCTGACCTGGCCCGCCTGCACCCTACCAGCTGTGCTCCTAACGGCCTGAACCCCAACCTCATGGTGACGGGGGGCCCGGC
GCTGGCGGGCTCAGGTCGCTGGTCTGCCGACCCCGCAGCCCATCTGGCCACGCACCCCTGGTTGCCCCGCTCGGGCAACGCATCCATGTG
GCTCGCTGGACACCCCTACGGCTTGGGTCCCCCATCTCTGCACCAGGGCATGGCCCCTGCGTTCCCACCTGGCCTGGGGGGCTCCCTCCC
GTCAGCCTACCAGTTTGTCAGGGACCCCCAATCGGGCCAGCTGGTGGTCATTCCCAGTGATCACCTTCCTCACTTTGCGGAGCTGATGGA
GCGGGCCACCGTACCGCCCCTCTGGCCCGCCCTGTACCCGCCGGGCCGCAGCCCCCTGCACCACGCCCAGCAGCTGCAGCTCTTCTCACA
GCAGCACTTCCTGCGGCAGCAGGAGTTCCTGTACCTGCAGCAGCAGGCGGCCCAGGCCTTGGAACTGCAGAGGAGCGCCCAGCTCGTGCA
GGAGCGGTTGAAGGCGCAGGAGCACCGGGCGGAGATGGAAGAGAAGGGGAGCAAGCGGGGCCTGGAGGCTGCGGGCAAGGCTGGCCTGGC
CACCGCCGGCCCCGGGCTGCTGCCGCGGAAGCCCCCTGGCCTGGCCGCCGGCCCCGCGGGCACCTACGGCAAGGCCGTGAGCCCGCCACC
ATCACCCCGCGCATCCCCTGTGGCTGCCCTGAAGGCCAAGGTCATCCAGAAGCTGGAGGACGTGTCCAAGCCACCCGCCTACGCCTACCC
CGCCACCCCCAGCTCCCACCCCACCAGCCCGCCGCCCGCCTCCCCACCGCCCACCCCGGGTATCACCCGCAAGGAGGAGGCTCCCGAGAA
TGTGGTCGAGAAGAAAGACTTGGAGTTGGAGAAGGAAGCCCCCAGCCCCTTCCAGGCCCTGTTCTCAGATATCCCGCCCAGGTACCCGTT
CCAAGCCCTGCCACCGCACTACGGGAGGCCCTACCCTTTCCTGCTGCAGCCCACGGCCGCCGCCGACGCGGACGGCTTGGCCCCTGATGT
GCCGCTCCCGGCTGATGGGCCCGAGCGCCTGGCACTCTCACCCGAAGACAAGCCCATCCGCTTGTCCCCCTCCAAGATCACAGAGCCGCT
GCGGGAGGGCCCGGAGGAAGAACCGCTGGCTGAGCGGGAGGTGAAGGCAGAGGTGGAGGACATGGACGAGGGCCCCACAGAGCTGCCGCC
TCTGGAGTCGCCGCTGCCACTGCCCGCCGCGGAAGCCATGGCTACCCCCAGCCCTGCAGGGGGTTGTGGAGGTGGCCTGTTGGAGGCCCA
GGCGCTGAGTGCCACCGGGCAGAGCTGCGCAGAGCCCTCTGAGTGTCCAGACTTTGTGGAGGGGCCTGAACCACGGGTGGATTCCCCGGG
CCGGACAGAACCCTGCACCGCCGCCCTGGACCTGGGGGTGCAGCTGACACCCGAGACACTGGTGGAGGCCAAGGAGGAGCCGGTGGAGGT
GCCTGTGGCGGTGCCCGTGGTGGAGGCAGTGCCCGAGGAAGGCCTGGCGCAGGTGGCACCGAGCGAGTCCCAGCCCACCCTAGAAATGTC
AGACTGTGACGTGCCCGCCGGGGAGGGACAGTGCCCGAGCCTGGAGCCCCAAGAGGCCGTGCCTGTACTCGGCAGCACCTGCTTCCTGGA
AGAGGCAAGCTCTGACCAGTTCCTGCCCAGTCTGGAGGACCCACTGGCTGGCATGAACGCCCTGGCGGCAGCTGCGGAGCTGCCCCAGGC
CAGGCCTCTGCCCTCCCCGGGTGCTGCTGGAGCCCAGGCCTTGGAGAAGCTGGAAGCAGCCGAGAGCCTTGTCTTGGAGCAGAGCTTCCT
GCATGGCATCACCCTGCTAAGTGAGATCGCAGAGCTGGAGCTGGAGAGGAGGAGCCAAGAGATGGGAGGAAACCTGTAGGAAGTGTCAGG
GACTCTGGAAAGAACATAATGGCCTCACCTGTGAAGAGCTGGCTGAAAAAGACGACATCAAGTACCGTACCTCTATTGAAGAAAAAATGA
CTGCTGCCCGCATTAGAAAATGCCACAAGTGTGGGACTGGCCTCATCAAATCTGAAGGCTGCAACCGCATGTCTTGCCGCTGTGGTGCCC
AGATGTGCTACCTCTGTCGAGTTTCTATTAATGGATATGACCATTTCTGCCAACATCCCCGCTCACCAGGAGCCCCTTGCCAGGAGTGTT
CAAGATGCTCTCTCTGGACCGATCCCACTGAAGATGATGAGAAGCTTATTGAGGAAATCCAGAAGGAGGCTGAAGAGGAACAGAAAAGAA
AGAATGGAGAGAACACCTTCAAACGCATTGGACCCCCGCTGGAGAAGCCTGTGGAGAAGGTGCAGAGGGTGGAGGCCCTCCCGAGGCCCG
TTCCGCAGAACCTGCCACAGCCACAGATGCCACCCTATGCCTTCGCGCACCCACCCTTCCCCCTGCCTCCCGTGCGGCCTGTGTTCAACA
ACTTCCCACTCAACATGGGGCCTATCCCAGCCCCGTACGTGCCCCCTCTGCCCAACGTGCGGGTCAACTATGACTTCGGTCCCATCCACA
TGCCCCTGGAGCACAACCTGCCCATGCACTTTGGCCCCCAGCCGCGGCATCGCTTCTGATGGCCCCGAATCCCCATTGAGCAGCACAAAG
CCCGTTTGGGGTAGGAGTGTGGATGGAGAACCCTCCCCCAAGGCTGGTGTCTGTACCATTGCATCCTAAGTCAGCTTGAAGGGTAGGCTG
GTTTTCTTCCCACCCCTTTCCTAGAAGGGCTACTGCTCCTGGAAGAGTGGACGGATCCATAATAAAGACGTCCCAAATGGTGGAGTTCGG

>92838_92838_5_TNRC18-RNF216_TNRC18_chr7_5410006_ENST00000399537_RNF216_chr7_5692141_ENST00000389902_length(amino acids)=1417AA_BP=
MIAALPRRMDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGEAFLGSFVASGMGPSASSH
GSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGA
PGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERL
SPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAAT
PAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPA
DAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHH
SRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPE
PAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLVDQERSLS
LSNVKGHGRADEDCVDDRARHREERLLGARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAHLATH
PWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPPLWPALYPPGRSP
LHHAQQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGP
AGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQ
ALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEV
EDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPE
TLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGM

--------------------------------------------------------------
>92838_92838_6_TNRC18-RNF216_TNRC18_chr7_5410006_ENST00000399537_RNF216_chr7_5692141_ENST00000425013_length(transcript)=8092nt_BP=4568nt
GGCCGCGGGATGGCGGGCAGCAGGGGCGCCTAGCTGCGCCGGGAGCCGGGGCCGCCGCCGGAGTCGTTGTCGCCGGAGCCTGGAGCCGTG
AACCCAGCCGCGCCAGACGCCGTGTGCGCCGCCTCGCGCAGCTCCGCCTGGCCGCCCGGAGGGGCCCCACCGCCGGCCGCCTGTGCGCCC
CGGGCCGCGGGCCCGCCGCCGAGCGCAAGCCCCGCTGGCCGCCGCCATGCACGCCGCGGAGCCCCCGCCGCCCGAGGACTCTGGGACTAC
GCCGAGGCCGAACTTTTAGGTCCCACTGAGCTAGGCCTGCGGGCCGGGTGGGGGGCTGATCGCGGCACTCCCGCGGAGGATGGATGGCCG
AGACTTCGGGCCCCAGCGGTCCGTGCACGGTCCCCCGCCGCCGCTGCTGTCCGGCCTGGCCATGGACAGCCACCGCGTGGGCGCGGCCAC
TGCCGGACGCTTGCCCGCCTCGGGCTTGCCCGGCCCGCTGCCGCCCGGGAAGTACATGGCCGGCCTGAATCTCCATCCGCACCCGGGCGA
GGCCTTCTTGGGCAGCTTTGTGGCCAGCGGGATGGGGCCCTCGGCCTCGTCCCATGGGAGCCCAGTGCCACTGCCCTCTGACCTGTCTTT
CCGCTCCCCAACCCCTAGCAACCTGCCCATGGTGCAGCTGTGGGCCGCCCACGCCCATGAAGGCTTCTCCCACCTGCCCAGTGGGCTGTA
CCCATCCTACCTCCACCTGAACCACCTGGAGCCCCCCAGCAGTGGGAGCCCCCTCCTCAGCCAGCTGGGTCAGCCCAGCATTTTCGATAC
CCAGAAAGGTCAGGGGCCAGGAGGAGACGGTTTCTACCTGCCCACCGCGGGGGCTCCGGGCTCCCTGCACTCTCACGCGCCCTCGGCCCG
GACCCCTGGCGGCGGCCACTCCTCGGGCGCCCCGGCCAAAGGCTCGTCGTCGCGGGACGGTCCAGCCAAGGAGCGGGCGGGCCGCGGCGG
GGAGCCGCCTCCGCTTTTCGGCAAGAAGGACCCGCGCGCCCGGGGCGAGGAGGCCTCGGGGCCACGGGGCGTGGTGGACCTGACCCAGGA
GGCGCGCGCCGAGGGCCGCCAGGACCGGGGGCCCCCGCGCCTGGCTGAGCGCCTGTCGCCCTTCCTGGCTGAGTCCAAGACCAAGAATGC
GGCGCTGCAGCCGTCGGTACTGACCATGTGCAACGGCGGCGCCGGGGACGTGGGGCTGCCCGCGCTGGTGGCCGAAGCGGGGCGCGGGGG
TGCCAAGGAGGCTGCCCGGCAGGACGAGGGCGCGCGGCTGCTGCGGCGCACGGAGACCCTGCTCCCTGGGCCGCGCCCCTGCCCCTCACC
GCTGCCCCCGCCGCCCGCGCCCCCCAAGGGGCCTCCTGCACCCCCCGCGGCCACCCCCGCCGGCGTCTACACCGTCTTCCGCGAGCAGGG
CCGTGAGCACCGCGTGGTGGCGCCCACCTTCGTGCCTTCCGTGGAGGCCTTCGACGAGCGCCCGGGGCCCATCCAGATCGCATCCCAGGC
GCGCGATGCCCGGGCCCGCGAGCGCGAGGCTGGCAGGCCAGGGGTCCTGCAGGCGCCCCCCGGCTCCCCGCGGCCTCTGGACCGGCCCGA
GGGCCTGCGCGAGAAGAACTCGGTCATCCGCTCGCTCAAGCGGCCGCCCCCCGCGGATGCCCCCACGGTGCGGGCCACACGCGCCTCCCC
GGACCCCCGCGCCTACGTGCCTGCCAAGGAGCTGCTCAAGCCCGAGGCGGACCCGAGGCCCTGCGAGCGTGCGCCCCGCGGCCCAGCCGG
TCCTGCAGCCCAACAGGCCGCCAAGCTCTTCGGCCTGGAGCCCGGGCGCCCCCCGCCCACCGGCCCTGAGCATAAATGGAAACCCTTCGA
GCTGGGCAACTTCGCCGCCACGCAGATGGCCGTGCTGGCCGCGCAGCACCACCACAGCCGCGCCGAAGAGGAGGCCGCCGTGGTCGCTGC
CTCCTCCTCCAAGAAGGCCTACCTGGACCCTGGGGCTGTGCTGCCCCGCTCGGCGGCCACCTGCGGCCGGCCGGTCGCTGACATGCACTC
TGCGGCCCACGGGTCTGGAGAGGCCTCGGCCATGCAGAGCCTTATAAAGTACAGTGGCAGCTTTGCCCGGGACGCCGTGGCCGTGCGCCC
TGGTGGCTGTGGCAAGAAGAGCCCCTTTGGAGGTTTGGGCACCATGAAACCCGAGCCTGCGCCCACCTCTGCGGGTGCCTCCCGAGCCCA
GGCCCGTCTCCCACACTCCGGAGGCCCTGCAGCGGGCGGCGGCCGGCAGCTGAAGCGGGACCCCGAGAGGCCCGAGAGCGCCAAAGCTTT
CGGGCGCGAGGGCTCTGGTGCCCAGGGTGAGGCAGAAGTGCGACACCCGCCTGTGGGCATTGCAGTGGCTGTGGCCCGGCAGAAGGACAG
TGGCGGCAGTGGCCGGCTGGGGCCTGGGCTGGTAGACCAGGAGCGCTCTCTGTCGCTGAGTAACGTCAAAGGGCACGGCCGAGCAGATGA
GGACTGTGTGGACGACCGGGCCAGACACCGGGAGGAACGGCTGCTCGGGGCACGGCTGGACCGGGATCAGGAGAAGCTGCTCAGAGAGAG
TAAGGAGCTGGCTGACCTGGCCCGCCTGCACCCTACCAGCTGTGCTCCTAACGGCCTGAACCCCAACCTCATGGTGACGGGGGGCCCGGC
GCTGGCGGGCTCAGGTCGCTGGTCTGCCGACCCCGCAGCCCATCTGGCCACGCACCCCTGGTTGCCCCGCTCGGGCAACGCATCCATGTG
GCTCGCTGGACACCCCTACGGCTTGGGTCCCCCATCTCTGCACCAGGGCATGGCCCCTGCGTTCCCACCTGGCCTGGGGGGCTCCCTCCC
GTCAGCCTACCAGTTTGTCAGGGACCCCCAATCGGGCCAGCTGGTGGTCATTCCCAGTGATCACCTTCCTCACTTTGCGGAGCTGATGGA
GCGGGCCACCGTACCGCCCCTCTGGCCCGCCCTGTACCCGCCGGGCCGCAGCCCCCTGCACCACGCCCAGCAGCTGCAGCTCTTCTCACA
GCAGCACTTCCTGCGGCAGCAGGAGTTCCTGTACCTGCAGCAGCAGGCGGCCCAGGCCTTGGAACTGCAGAGGAGCGCCCAGCTCGTGCA
GGAGCGGTTGAAGGCGCAGGAGCACCGGGCGGAGATGGAAGAGAAGGGGAGCAAGCGGGGCCTGGAGGCTGCGGGCAAGGCTGGCCTGGC
CACCGCCGGCCCCGGGCTGCTGCCGCGGAAGCCCCCTGGCCTGGCCGCCGGCCCCGCGGGCACCTACGGCAAGGCCGTGAGCCCGCCACC
ATCACCCCGCGCATCCCCTGTGGCTGCCCTGAAGGCCAAGGTCATCCAGAAGCTGGAGGACGTGTCCAAGCCACCCGCCTACGCCTACCC
CGCCACCCCCAGCTCCCACCCCACCAGCCCGCCGCCCGCCTCCCCACCGCCCACCCCGGGTATCACCCGCAAGGAGGAGGCTCCCGAGAA
TGTGGTCGAGAAGAAAGACTTGGAGTTGGAGAAGGAAGCCCCCAGCCCCTTCCAGGCCCTGTTCTCAGATATCCCGCCCAGGTACCCGTT
CCAAGCCCTGCCACCGCACTACGGGAGGCCCTACCCTTTCCTGCTGCAGCCCACGGCCGCCGCCGACGCGGACGGCTTGGCCCCTGATGT
GCCGCTCCCGGCTGATGGGCCCGAGCGCCTGGCACTCTCACCCGAAGACAAGCCCATCCGCTTGTCCCCCTCCAAGATCACAGAGCCGCT
GCGGGAGGGCCCGGAGGAAGAACCGCTGGCTGAGCGGGAGGTGAAGGCAGAGGTGGAGGACATGGACGAGGGCCCCACAGAGCTGCCGCC
TCTGGAGTCGCCGCTGCCACTGCCCGCCGCGGAAGCCATGGCTACCCCCAGCCCTGCAGGGGGTTGTGGAGGTGGCCTGTTGGAGGCCCA
GGCGCTGAGTGCCACCGGGCAGAGCTGCGCAGAGCCCTCTGAGTGTCCAGACTTTGTGGAGGGGCCTGAACCACGGGTGGATTCCCCGGG
CCGGACAGAACCCTGCACCGCCGCCCTGGACCTGGGGGTGCAGCTGACACCCGAGACACTGGTGGAGGCCAAGGAGGAGCCGGTGGAGGT
GCCTGTGGCGGTGCCCGTGGTGGAGGCAGTGCCCGAGGAAGGCCTGGCGCAGGTGGCACCGAGCGAGTCCCAGCCCACCCTAGAAATGTC
AGACTGTGACGTGCCCGCCGGGGAGGGACAGTGCCCGAGCCTGGAGCCCCAAGAGGCCGTGCCTGTACTCGGCAGCACCTGCTTCCTGGA
AGAGGCAAGCTCTGACCAGTTCCTGCCCAGTCTGGAGGACCCACTGGCTGGCATGAACGCCCTGGCGGCAGCTGCGGAGCTGCCCCAGGC
CAGGCCTCTGCCCTCCCCGGGTGCTGCTGGAGCCCAGGCCTTGGAGAAGCTGGAAGCAGCCGAGAGCCTTGTCTTGGAGCAGAGCTTCCT
GCATGGCATCACCCTGCTAAGTGAGATCGCAGAGCTGGAGCTGGAGAGGAGGAGCCAAGAGATGGGAGGAAACCTGTAGGAAGTGTCAGG
GACTCTGGAAAGAACATAATGGCCTCACCTGTGAAGAGCTGGCTGAAAAAGACGACATCAAGTACCGTACCTCTATTGAAGAAAAAATGA
CTGCTGCCCGCATTAGAAAATGCCACAAGTGTGGGACTGGCCTCATCAAATCTGAAGGCTGCAACCGCATGTCTTGCCGCTGTGGTGCCC
AGATGTGCTACCTCTGTCGAGTTTCTATTAATGGATATGACCATTTCTGCCAACATCCCCGCTCACCAGGAGCCCCTTGCCAGGAGTGTT
CAAGATGCTCTCTCTGGACCGATCCCACTGAAGATGATGAGAAGCTTATTGAGGAAATCCAGAAGGAGGCTGAAGAGGAACAGAAAAGAA
AGAATGGAGAGAACACCTTCAAACGCATTGGACCCCCGCTGGAGAAGCCTGTGGAGAAGGTGCAGAGGGTGGAGGCCCTCCCGAGGCCCG
TTCCGCAGAACCTGCCACAGCCACAGATGCCACCCTATGCCTTCGCGCACCCACCCTTCCCCCTGCCTCCCGTGCGGCCTGTGTTCAACA
ACTTCCCACTCAACATGGGGCCTATCCCAGCCCCGTACGTGCCCCCTCTGCCCAACGTGCGGGTCAACTATGACTTCGGTCCCATCCACA
TGCCCCTGGAGCACAACCTGCCCATGCACTTTGGCCCCCAGCCGCGGCATCGCTTCTGATGGCCCCGAATCCCCATTGAGCAGCACAAAG
CCCGTTTGGGGTAGGAGTGTGGATGGAGAACCCTCCCCCAAGGCTGGTGTCTGTACCATTGCATCCTAAGTCAGCTTGAAGGGTAGGCTG
GTTTTCTTCCCACCCCTTTCCTAGAAGGGCTACTGCTCCTGGAAGAGTGGACGGATCCATAATAAAGACGTCCCAAATGGTGGAGTTCGG
AGAGAGCTGCGATGTGAACTGCCCCTCCCCTCGCATCCCCCAGGCCACCAACGGCAGTCCTTCTGCCTTGTCCATGGCATAGGCCATAGA
CCAGGTCCCTGCTGCTCACACCTGGGCCTCTCCTCGGAGCCGACCCCTGGGTAGCAAGGCAGCCGAGAGCATCTCCCTGGAGGGGCCCAC
GGTTGGGCCAAGGGCAGAGGGGGCTGCACCTGCGGGCCTGGGAAGCATTGCTCAGGGTGGGGGGCTGGGACCATGGCCCGCAGAGGCACT
GCCACAGCTGTGAGGGCCAAGATGCTGTCCCCCCATCCAAAACCCGTGCGCCACTGCAGTGAGTGTTGAGGGCACCTCTCCTCCCCTCTT
ACACCTACTCAGATGAGGCAGCAGCAGACCCATCTCGCGGCGGGGGTTTTGTTCTGTTGCCGCCTAACTTTCTCATCCTCGGTCTCTGGA
AAGTCAGGCTGAGAAATCCTTTCCCAGGCCAGGCCGCTGCGGTACACTGGATGGTTCTGAAGCTGGCCCATTGAAAGAGCCTCTTAAGGC
AGCTGGGACAGAGGCCTGGTGGCCCTGCTGGGCAGCCCAACTGCTGGGGGAGACGTTTCTGCCACCCTGGGTGATGAGCAGCTTTTCCCC
CCTGGCTTTCTGGGGGAGGAGTGGGCCTCCTTAGGGAGACAGGTGACCCTGGGTGCCACCCCTGCCCCGTGTGTGCCCCGGGTGTTCTCA
GTGGTTGCTGAAGGCAGGTAGAGGGTGCTGTCCAGTATCCCCCATGTGAAGGTCACTTCCCTTCTCATGGAGTCAGCTGAGCATCAGCTC
AGCCCTGCCATGTCCCCACTCACCCTCCTCGCCTCCTGTCCGGCCCTGGGTTTCTAGCGGTGCCTGAGGCATCACTCTGGCCCATTGACA
GATGAGAGGTCTGAAGCCTTCCTGGCCACAGGCATCACTTTCTCCTCCTCCTCATGCCCTGCCTTGTCCTTGTCGTGTTGCCATGGGGTT
CTGAGAGGCTGGGAGTTCACAGACCTCAGACACAGCTGAGTCCGACAACCATTGGGGTGGGGCTGCATCAGTCTCCGGAGTGGCCCGCCA
CCTCCTGAAGCAGGGCCTGGCCCACCCAAGGTGCCTGGGGCAGGCGGGCACCGTCATTCGCTGCCATTGGCTTCTCAGATGTATTTCAAG
GACTAAAGTGGGCTCTAAGATCTAAGATGGCCCGGCGCGGTGGCTCCCGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATG
AGTTGAGGTCGGGAGTTTGAGTCCCCGTCTCTACTAAAAATACAAAATTAGCCGGACAAGGTGGCGCATGCCTATAATCCCAGGTACTCA
GGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGAGCAACAA
AAGCAAAACTCTATCTTTAAAAAAAAAAAAAAAAAAACTAAGATACCCATTCTTTCTGCCTTTGCCCAGGATGGAGGCTTTGAAGACAGG
TGGTCACCTGGACCTGGGGTAAGGGTGCGCAGGGAGGCCGGGCTTGGGGGCAGCCTGCTGCTATGTCCTTGCTGGCGCCCATACCTGTTG
GACTGCCTGAACTTTGCTACTAGCCTGAACGACAGTGCCTTGGAAAGGCAGGCTCCATGCGGCAGCAACAGGATTGTCTTCGGTACCTTA
AATATGCTCCCTGTGCTTCCCCAGGGAGGATCTCTGGGAGCAGAGGGCGGCTGTAGACATCACAGCTGAAGAGGTGACCTCAGGCCCTGG
GAGCCTCAGCTCCCTCTGCCCTGTACCCTAGGCACGTGGCTCCAGCAAGAGCCCCAGGCAGGACAAAGGGAGCAGGCAGCAGCTGCAGAA
ACAGCCCTAGACAGGTGCTGGCCTCAACCCTGGCAGGGGAGGGGGAGCCCAGAGTGATGTTTCTCCTAAGGCCAAACCCCAGGGGTGGGT
CATTTGAGAGGAGTTCCAGCTGTTCTGGCCACACTGGGCTGGTGGGGAAGGAGCGGCGGCCTCTTTCCTTGGAGGGTCCCTGATTCCTGA
GGATCCTCCCCGAGCCAGGCACGGGGGACCACAGGGCTGCCGTGAGCACCCACCCTGGTTCTCCAGGCCCCTCTGTCCAGAGGCAGGGCC
TGAACCTCGGGCTCCTGCCTGGACCAGTGACAGCATTGGGGAGAGAAGCACTGGGGGTCTTCAGACCAGCCAGCAAGGGGCCGTGCCAGT
GCCCAGAGAGCAGGTCAGACAACAGGCAACCCTGAGGCAGCTGGCTCCCTCTCTCTGCCCTGCAGGGCTTGCCGCAGGGCGTGAGGCTCC
CCAGCCACAGCCCCCTCTTACTTGCCTTAAAACTGGAGAGAGGAATCTAGTATTTGCACTTAGCAAAATATTTAAAAACTGAAAAAAATG
TGCATGATCTGTCACTTTGTATAAAAACAAGAAACGATTAGTTCATTAAACTTTTTCTTTACCTTCTGGTAGTAAAAATAGATAAAATAA

>92838_92838_6_TNRC18-RNF216_TNRC18_chr7_5410006_ENST00000399537_RNF216_chr7_5692141_ENST00000425013_length(amino acids)=1417AA_BP=
MIAALPRRMDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGEAFLGSFVASGMGPSASSH
GSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGA
PGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERL
SPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAAT
PAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPA
DAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHH
SRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPE
PAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLVDQERSLS
LSNVKGHGRADEDCVDDRARHREERLLGARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAHLATH
PWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPPLWPALYPPGRSP
LHHAQQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGP
AGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQ
ALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEV
EDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPE
TLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGM

--------------------------------------------------------------
>92838_92838_7_TNRC18-RNF216_TNRC18_chr7_5410006_ENST00000430969_RNF216_chr7_5692141_ENST00000389902_length(transcript)=5532nt_BP=4568nt
GGCCGCGGGATGGCGGGCAGCAGGGGCGCCTAGCTGCGCCGGGAGCCGGGGCCGCCGCCGGAGTCGTTGTCGCCGGAGCCTGGAGCCGTG
AACCCAGCCGCGCCAGACGCCGTGTGCGCCGCCTCGCGCAGCTCCGCCTGGCCGCCCGGAGGGGCCCCACCGCCGGCCGCCTGTGCGCCC
CGGGCCGCGGGCCCGCCGCCGAGCGCAAGCCCCGCTGGCCGCCGCCATGCACGCCGCGGAGCCCCCGCCGCCCGAGGACTCTGGGACTAC
GCCGAGGCCGAACTTTTAGGTCCCACTGAGCTAGGCCTGCGGGCCGGGTGGGGGGCTGATCGCGGCACTCCCGCGGAGGATGGATGGCCG
AGACTTCGGGCCCCAGCGGTCCGTGCACGGTCCCCCGCCGCCGCTGCTGTCCGGCCTGGCCATGGACAGCCACCGCGTGGGCGCGGCCAC
TGCCGGACGCTTGCCCGCCTCGGGCTTGCCCGGCCCGCTGCCGCCCGGGAAGTACATGGCCGGCCTGAATCTCCATCCGCACCCGGGCGA
GGCCTTCTTGGGCAGCTTTGTGGCCAGCGGGATGGGGCCCTCGGCCTCGTCCCATGGGAGCCCAGTGCCACTGCCCTCTGACCTGTCTTT
CCGCTCCCCAACCCCTAGCAACCTGCCCATGGTGCAGCTGTGGGCCGCCCACGCCCATGAAGGCTTCTCCCACCTGCCCAGTGGGCTGTA
CCCATCCTACCTCCACCTGAACCACCTGGAGCCCCCCAGCAGTGGGAGCCCCCTCCTCAGCCAGCTGGGTCAGCCCAGCATTTTCGATAC
CCAGAAAGGTCAGGGGCCAGGAGGAGACGGTTTCTACCTGCCCACCGCGGGGGCTCCGGGCTCCCTGCACTCTCACGCGCCCTCGGCCCG
GACCCCTGGCGGCGGCCACTCCTCGGGCGCCCCGGCCAAAGGCTCGTCGTCGCGGGACGGTCCAGCCAAGGAGCGGGCGGGCCGCGGCGG
GGAGCCGCCTCCGCTTTTCGGCAAGAAGGACCCGCGCGCCCGGGGCGAGGAGGCCTCGGGGCCACGGGGCGTGGTGGACCTGACCCAGGA
GGCGCGCGCCGAGGGCCGCCAGGACCGGGGGCCCCCGCGCCTGGCTGAGCGCCTGTCGCCCTTCCTGGCTGAGTCCAAGACCAAGAATGC
GGCGCTGCAGCCGTCGGTACTGACCATGTGCAACGGCGGCGCCGGGGACGTGGGGCTGCCCGCGCTGGTGGCCGAAGCGGGGCGCGGGGG
TGCCAAGGAGGCTGCCCGGCAGGACGAGGGCGCGCGGCTGCTGCGGCGCACGGAGACCCTGCTCCCTGGGCCGCGCCCCTGCCCCTCACC
GCTGCCCCCGCCGCCCGCGCCCCCCAAGGGGCCTCCTGCACCCCCCGCGGCCACCCCCGCCGGCGTCTACACCGTCTTCCGCGAGCAGGG
CCGTGAGCACCGCGTGGTGGCGCCCACCTTCGTGCCTTCCGTGGAGGCCTTCGACGAGCGCCCGGGGCCCATCCAGATCGCATCCCAGGC
GCGCGATGCCCGGGCCCGCGAGCGCGAGGCTGGCAGGCCAGGGGTCCTGCAGGCGCCCCCCGGCTCCCCGCGGCCTCTGGACCGGCCCGA
GGGCCTGCGCGAGAAGAACTCGGTCATCCGCTCGCTCAAGCGGCCGCCCCCCGCGGATGCCCCCACGGTGCGGGCCACACGCGCCTCCCC
GGACCCCCGCGCCTACGTGCCTGCCAAGGAGCTGCTCAAGCCCGAGGCGGACCCGAGGCCCTGCGAGCGTGCGCCCCGCGGCCCAGCCGG
TCCTGCAGCCCAACAGGCCGCCAAGCTCTTCGGCCTGGAGCCCGGGCGCCCCCCGCCCACCGGCCCTGAGCATAAATGGAAACCCTTCGA
GCTGGGCAACTTCGCCGCCACGCAGATGGCCGTGCTGGCCGCGCAGCACCACCACAGCCGCGCCGAAGAGGAGGCCGCCGTGGTCGCTGC
CTCCTCCTCCAAGAAGGCCTACCTGGACCCTGGGGCTGTGCTGCCCCGCTCGGCGGCCACCTGCGGCCGGCCGGTCGCTGACATGCACTC
TGCGGCCCACGGGTCTGGAGAGGCCTCGGCCATGCAGAGCCTTATAAAGTACAGTGGCAGCTTTGCCCGGGACGCCGTGGCCGTGCGCCC
TGGTGGCTGTGGCAAGAAGAGCCCCTTTGGAGGTTTGGGCACCATGAAACCCGAGCCTGCGCCCACCTCTGCGGGTGCCTCCCGAGCCCA
GGCCCGTCTCCCACACTCCGGAGGCCCTGCAGCGGGCGGCGGCCGGCAGCTGAAGCGGGACCCCGAGAGGCCCGAGAGCGCCAAAGCTTT
CGGGCGCGAGGGCTCTGGTGCCCAGGGTGAGGCAGAAGTGCGACACCCGCCTGTGGGCATTGCAGTGGCTGTGGCCCGGCAGAAGGACAG
TGGCGGCAGTGGCCGGCTGGGGCCTGGGCTGGTAGACCAGGAGCGCTCTCTGTCGCTGAGTAACGTCAAAGGGCACGGCCGAGCAGATGA
GGACTGTGTGGACGACCGGGCCAGACACCGGGAGGAACGGCTGCTCGGGGCACGGCTGGACCGGGATCAGGAGAAGCTGCTCAGAGAGAG
TAAGGAGCTGGCTGACCTGGCCCGCCTGCACCCTACCAGCTGTGCTCCTAACGGCCTGAACCCCAACCTCATGGTGACGGGGGGCCCGGC
GCTGGCGGGCTCAGGTCGCTGGTCTGCCGACCCCGCAGCCCATCTGGCCACGCACCCCTGGTTGCCCCGCTCGGGCAACGCATCCATGTG
GCTCGCTGGACACCCCTACGGCTTGGGTCCCCCATCTCTGCACCAGGGCATGGCCCCTGCGTTCCCACCTGGCCTGGGGGGCTCCCTCCC
GTCAGCCTACCAGTTTGTCAGGGACCCCCAATCGGGCCAGCTGGTGGTCATTCCCAGTGATCACCTTCCTCACTTTGCGGAGCTGATGGA
GCGGGCCACCGTACCGCCCCTCTGGCCCGCCCTGTACCCGCCGGGCCGCAGCCCCCTGCACCACGCCCAGCAGCTGCAGCTCTTCTCACA
GCAGCACTTCCTGCGGCAGCAGGAGTTCCTGTACCTGCAGCAGCAGGCGGCCCAGGCCTTGGAACTGCAGAGGAGCGCCCAGCTCGTGCA
GGAGCGGTTGAAGGCGCAGGAGCACCGGGCGGAGATGGAAGAGAAGGGGAGCAAGCGGGGCCTGGAGGCTGCGGGCAAGGCTGGCCTGGC
CACCGCCGGCCCCGGGCTGCTGCCGCGGAAGCCCCCTGGCCTGGCCGCCGGCCCCGCGGGCACCTACGGCAAGGCCGTGAGCCCGCCACC
ATCACCCCGCGCATCCCCTGTGGCTGCCCTGAAGGCCAAGGTCATCCAGAAGCTGGAGGACGTGTCCAAGCCACCCGCCTACGCCTACCC
CGCCACCCCCAGCTCCCACCCCACCAGCCCGCCGCCCGCCTCCCCACCGCCCACCCCGGGTATCACCCGCAAGGAGGAGGCTCCCGAGAA
TGTGGTCGAGAAGAAAGACTTGGAGTTGGAGAAGGAAGCCCCCAGCCCCTTCCAGGCCCTGTTCTCAGATATCCCGCCCAGGTACCCGTT
CCAAGCCCTGCCACCGCACTACGGGAGGCCCTACCCTTTCCTGCTGCAGCCCACGGCCGCCGCCGACGCGGACGGCTTGGCCCCTGATGT
GCCGCTCCCGGCTGATGGGCCCGAGCGCCTGGCACTCTCACCCGAAGACAAGCCCATCCGCTTGTCCCCCTCCAAGATCACAGAGCCGCT
GCGGGAGGGCCCGGAGGAAGAACCGCTGGCTGAGCGGGAGGTGAAGGCAGAGGTGGAGGACATGGACGAGGGCCCCACAGAGCTGCCGCC
TCTGGAGTCGCCGCTGCCACTGCCCGCCGCGGAAGCCATGGCTACCCCCAGCCCTGCAGGGGGTTGTGGAGGTGGCCTGTTGGAGGCCCA
GGCGCTGAGTGCCACCGGGCAGAGCTGCGCAGAGCCCTCTGAGTGTCCAGACTTTGTGGAGGGGCCTGAACCACGGGTGGATTCCCCGGG
CCGGACAGAACCCTGCACCGCCGCCCTGGACCTGGGGGTGCAGCTGACACCCGAGACACTGGTGGAGGCCAAGGAGGAGCCGGTGGAGGT
GCCTGTGGCGGTGCCCGTGGTGGAGGCAGTGCCCGAGGAAGGCCTGGCGCAGGTGGCACCGAGCGAGTCCCAGCCCACCCTAGAAATGTC
AGACTGTGACGTGCCCGCCGGGGAGGGACAGTGCCCGAGCCTGGAGCCCCAAGAGGCCGTGCCTGTACTCGGCAGCACCTGCTTCCTGGA
AGAGGCAAGCTCTGACCAGTTCCTGCCCAGTCTGGAGGACCCACTGGCTGGCATGAACGCCCTGGCGGCAGCTGCGGAGCTGCCCCAGGC
CAGGCCTCTGCCCTCCCCGGGTGCTGCTGGAGCCCAGGCCTTGGAGAAGCTGGAAGCAGCCGAGAGCCTTGTCTTGGAGCAGAGCTTCCT
GCATGGCATCACCCTGCTAAGTGAGATCGCAGAGCTGGAGCTGGAGAGGAGGAGCCAAGAGATGGGAGGAAACCTGTAGGAAGTGTCAGG
GACTCTGGAAAGAACATAATGGCCTCACCTGTGAAGAGCTGGCTGAAAAAGACGACATCAAGTACCGTACCTCTATTGAAGAAAAAATGA
CTGCTGCCCGCATTAGAAAATGCCACAAGTGTGGGACTGGCCTCATCAAATCTGAAGGCTGCAACCGCATGTCTTGCCGCTGTGGTGCCC
AGATGTGCTACCTCTGTCGAGTTTCTATTAATGGATATGACCATTTCTGCCAACATCCCCGCTCACCAGGAGCCCCTTGCCAGGAGTGTT
CAAGATGCTCTCTCTGGACCGATCCCACTGAAGATGATGAGAAGCTTATTGAGGAAATCCAGAAGGAGGCTGAAGAGGAACAGAAAAGAA
AGAATGGAGAGAACACCTTCAAACGCATTGGACCCCCGCTGGAGAAGCCTGTGGAGAAGGTGCAGAGGGTGGAGGCCCTCCCGAGGCCCG
TTCCGCAGAACCTGCCACAGCCACAGATGCCACCCTATGCCTTCGCGCACCCACCCTTCCCCCTGCCTCCCGTGCGGCCTGTGTTCAACA
ACTTCCCACTCAACATGGGGCCTATCCCAGCCCCGTACGTGCCCCCTCTGCCCAACGTGCGGGTCAACTATGACTTCGGTCCCATCCACA
TGCCCCTGGAGCACAACCTGCCCATGCACTTTGGCCCCCAGCCGCGGCATCGCTTCTGATGGCCCCGAATCCCCATTGAGCAGCACAAAG
CCCGTTTGGGGTAGGAGTGTGGATGGAGAACCCTCCCCCAAGGCTGGTGTCTGTACCATTGCATCCTAAGTCAGCTTGAAGGGTAGGCTG
GTTTTCTTCCCACCCCTTTCCTAGAAGGGCTACTGCTCCTGGAAGAGTGGACGGATCCATAATAAAGACGTCCCAAATGGTGGAGTTCGG

>92838_92838_7_TNRC18-RNF216_TNRC18_chr7_5410006_ENST00000430969_RNF216_chr7_5692141_ENST00000389902_length(amino acids)=1417AA_BP=
MIAALPRRMDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGEAFLGSFVASGMGPSASSH
GSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGA
PGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERL
SPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAAT
PAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPA
DAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHH
SRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPE
PAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLVDQERSLS
LSNVKGHGRADEDCVDDRARHREERLLGARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAHLATH
PWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPPLWPALYPPGRSP
LHHAQQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGP
AGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQ
ALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEV
EDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPE
TLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGM

--------------------------------------------------------------
>92838_92838_8_TNRC18-RNF216_TNRC18_chr7_5410006_ENST00000430969_RNF216_chr7_5692141_ENST00000425013_length(transcript)=8092nt_BP=4568nt
GGCCGCGGGATGGCGGGCAGCAGGGGCGCCTAGCTGCGCCGGGAGCCGGGGCCGCCGCCGGAGTCGTTGTCGCCGGAGCCTGGAGCCGTG
AACCCAGCCGCGCCAGACGCCGTGTGCGCCGCCTCGCGCAGCTCCGCCTGGCCGCCCGGAGGGGCCCCACCGCCGGCCGCCTGTGCGCCC
CGGGCCGCGGGCCCGCCGCCGAGCGCAAGCCCCGCTGGCCGCCGCCATGCACGCCGCGGAGCCCCCGCCGCCCGAGGACTCTGGGACTAC
GCCGAGGCCGAACTTTTAGGTCCCACTGAGCTAGGCCTGCGGGCCGGGTGGGGGGCTGATCGCGGCACTCCCGCGGAGGATGGATGGCCG
AGACTTCGGGCCCCAGCGGTCCGTGCACGGTCCCCCGCCGCCGCTGCTGTCCGGCCTGGCCATGGACAGCCACCGCGTGGGCGCGGCCAC
TGCCGGACGCTTGCCCGCCTCGGGCTTGCCCGGCCCGCTGCCGCCCGGGAAGTACATGGCCGGCCTGAATCTCCATCCGCACCCGGGCGA
GGCCTTCTTGGGCAGCTTTGTGGCCAGCGGGATGGGGCCCTCGGCCTCGTCCCATGGGAGCCCAGTGCCACTGCCCTCTGACCTGTCTTT
CCGCTCCCCAACCCCTAGCAACCTGCCCATGGTGCAGCTGTGGGCCGCCCACGCCCATGAAGGCTTCTCCCACCTGCCCAGTGGGCTGTA
CCCATCCTACCTCCACCTGAACCACCTGGAGCCCCCCAGCAGTGGGAGCCCCCTCCTCAGCCAGCTGGGTCAGCCCAGCATTTTCGATAC
CCAGAAAGGTCAGGGGCCAGGAGGAGACGGTTTCTACCTGCCCACCGCGGGGGCTCCGGGCTCCCTGCACTCTCACGCGCCCTCGGCCCG
GACCCCTGGCGGCGGCCACTCCTCGGGCGCCCCGGCCAAAGGCTCGTCGTCGCGGGACGGTCCAGCCAAGGAGCGGGCGGGCCGCGGCGG
GGAGCCGCCTCCGCTTTTCGGCAAGAAGGACCCGCGCGCCCGGGGCGAGGAGGCCTCGGGGCCACGGGGCGTGGTGGACCTGACCCAGGA
GGCGCGCGCCGAGGGCCGCCAGGACCGGGGGCCCCCGCGCCTGGCTGAGCGCCTGTCGCCCTTCCTGGCTGAGTCCAAGACCAAGAATGC
GGCGCTGCAGCCGTCGGTACTGACCATGTGCAACGGCGGCGCCGGGGACGTGGGGCTGCCCGCGCTGGTGGCCGAAGCGGGGCGCGGGGG
TGCCAAGGAGGCTGCCCGGCAGGACGAGGGCGCGCGGCTGCTGCGGCGCACGGAGACCCTGCTCCCTGGGCCGCGCCCCTGCCCCTCACC
GCTGCCCCCGCCGCCCGCGCCCCCCAAGGGGCCTCCTGCACCCCCCGCGGCCACCCCCGCCGGCGTCTACACCGTCTTCCGCGAGCAGGG
CCGTGAGCACCGCGTGGTGGCGCCCACCTTCGTGCCTTCCGTGGAGGCCTTCGACGAGCGCCCGGGGCCCATCCAGATCGCATCCCAGGC
GCGCGATGCCCGGGCCCGCGAGCGCGAGGCTGGCAGGCCAGGGGTCCTGCAGGCGCCCCCCGGCTCCCCGCGGCCTCTGGACCGGCCCGA
GGGCCTGCGCGAGAAGAACTCGGTCATCCGCTCGCTCAAGCGGCCGCCCCCCGCGGATGCCCCCACGGTGCGGGCCACACGCGCCTCCCC
GGACCCCCGCGCCTACGTGCCTGCCAAGGAGCTGCTCAAGCCCGAGGCGGACCCGAGGCCCTGCGAGCGTGCGCCCCGCGGCCCAGCCGG
TCCTGCAGCCCAACAGGCCGCCAAGCTCTTCGGCCTGGAGCCCGGGCGCCCCCCGCCCACCGGCCCTGAGCATAAATGGAAACCCTTCGA
GCTGGGCAACTTCGCCGCCACGCAGATGGCCGTGCTGGCCGCGCAGCACCACCACAGCCGCGCCGAAGAGGAGGCCGCCGTGGTCGCTGC
CTCCTCCTCCAAGAAGGCCTACCTGGACCCTGGGGCTGTGCTGCCCCGCTCGGCGGCCACCTGCGGCCGGCCGGTCGCTGACATGCACTC
TGCGGCCCACGGGTCTGGAGAGGCCTCGGCCATGCAGAGCCTTATAAAGTACAGTGGCAGCTTTGCCCGGGACGCCGTGGCCGTGCGCCC
TGGTGGCTGTGGCAAGAAGAGCCCCTTTGGAGGTTTGGGCACCATGAAACCCGAGCCTGCGCCCACCTCTGCGGGTGCCTCCCGAGCCCA
GGCCCGTCTCCCACACTCCGGAGGCCCTGCAGCGGGCGGCGGCCGGCAGCTGAAGCGGGACCCCGAGAGGCCCGAGAGCGCCAAAGCTTT
CGGGCGCGAGGGCTCTGGTGCCCAGGGTGAGGCAGAAGTGCGACACCCGCCTGTGGGCATTGCAGTGGCTGTGGCCCGGCAGAAGGACAG
TGGCGGCAGTGGCCGGCTGGGGCCTGGGCTGGTAGACCAGGAGCGCTCTCTGTCGCTGAGTAACGTCAAAGGGCACGGCCGAGCAGATGA
GGACTGTGTGGACGACCGGGCCAGACACCGGGAGGAACGGCTGCTCGGGGCACGGCTGGACCGGGATCAGGAGAAGCTGCTCAGAGAGAG
TAAGGAGCTGGCTGACCTGGCCCGCCTGCACCCTACCAGCTGTGCTCCTAACGGCCTGAACCCCAACCTCATGGTGACGGGGGGCCCGGC
GCTGGCGGGCTCAGGTCGCTGGTCTGCCGACCCCGCAGCCCATCTGGCCACGCACCCCTGGTTGCCCCGCTCGGGCAACGCATCCATGTG
GCTCGCTGGACACCCCTACGGCTTGGGTCCCCCATCTCTGCACCAGGGCATGGCCCCTGCGTTCCCACCTGGCCTGGGGGGCTCCCTCCC
GTCAGCCTACCAGTTTGTCAGGGACCCCCAATCGGGCCAGCTGGTGGTCATTCCCAGTGATCACCTTCCTCACTTTGCGGAGCTGATGGA
GCGGGCCACCGTACCGCCCCTCTGGCCCGCCCTGTACCCGCCGGGCCGCAGCCCCCTGCACCACGCCCAGCAGCTGCAGCTCTTCTCACA
GCAGCACTTCCTGCGGCAGCAGGAGTTCCTGTACCTGCAGCAGCAGGCGGCCCAGGCCTTGGAACTGCAGAGGAGCGCCCAGCTCGTGCA
GGAGCGGTTGAAGGCGCAGGAGCACCGGGCGGAGATGGAAGAGAAGGGGAGCAAGCGGGGCCTGGAGGCTGCGGGCAAGGCTGGCCTGGC
CACCGCCGGCCCCGGGCTGCTGCCGCGGAAGCCCCCTGGCCTGGCCGCCGGCCCCGCGGGCACCTACGGCAAGGCCGTGAGCCCGCCACC
ATCACCCCGCGCATCCCCTGTGGCTGCCCTGAAGGCCAAGGTCATCCAGAAGCTGGAGGACGTGTCCAAGCCACCCGCCTACGCCTACCC
CGCCACCCCCAGCTCCCACCCCACCAGCCCGCCGCCCGCCTCCCCACCGCCCACCCCGGGTATCACCCGCAAGGAGGAGGCTCCCGAGAA
TGTGGTCGAGAAGAAAGACTTGGAGTTGGAGAAGGAAGCCCCCAGCCCCTTCCAGGCCCTGTTCTCAGATATCCCGCCCAGGTACCCGTT
CCAAGCCCTGCCACCGCACTACGGGAGGCCCTACCCTTTCCTGCTGCAGCCCACGGCCGCCGCCGACGCGGACGGCTTGGCCCCTGATGT
GCCGCTCCCGGCTGATGGGCCCGAGCGCCTGGCACTCTCACCCGAAGACAAGCCCATCCGCTTGTCCCCCTCCAAGATCACAGAGCCGCT
GCGGGAGGGCCCGGAGGAAGAACCGCTGGCTGAGCGGGAGGTGAAGGCAGAGGTGGAGGACATGGACGAGGGCCCCACAGAGCTGCCGCC
TCTGGAGTCGCCGCTGCCACTGCCCGCCGCGGAAGCCATGGCTACCCCCAGCCCTGCAGGGGGTTGTGGAGGTGGCCTGTTGGAGGCCCA
GGCGCTGAGTGCCACCGGGCAGAGCTGCGCAGAGCCCTCTGAGTGTCCAGACTTTGTGGAGGGGCCTGAACCACGGGTGGATTCCCCGGG
CCGGACAGAACCCTGCACCGCCGCCCTGGACCTGGGGGTGCAGCTGACACCCGAGACACTGGTGGAGGCCAAGGAGGAGCCGGTGGAGGT
GCCTGTGGCGGTGCCCGTGGTGGAGGCAGTGCCCGAGGAAGGCCTGGCGCAGGTGGCACCGAGCGAGTCCCAGCCCACCCTAGAAATGTC
AGACTGTGACGTGCCCGCCGGGGAGGGACAGTGCCCGAGCCTGGAGCCCCAAGAGGCCGTGCCTGTACTCGGCAGCACCTGCTTCCTGGA
AGAGGCAAGCTCTGACCAGTTCCTGCCCAGTCTGGAGGACCCACTGGCTGGCATGAACGCCCTGGCGGCAGCTGCGGAGCTGCCCCAGGC
CAGGCCTCTGCCCTCCCCGGGTGCTGCTGGAGCCCAGGCCTTGGAGAAGCTGGAAGCAGCCGAGAGCCTTGTCTTGGAGCAGAGCTTCCT
GCATGGCATCACCCTGCTAAGTGAGATCGCAGAGCTGGAGCTGGAGAGGAGGAGCCAAGAGATGGGAGGAAACCTGTAGGAAGTGTCAGG
GACTCTGGAAAGAACATAATGGCCTCACCTGTGAAGAGCTGGCTGAAAAAGACGACATCAAGTACCGTACCTCTATTGAAGAAAAAATGA
CTGCTGCCCGCATTAGAAAATGCCACAAGTGTGGGACTGGCCTCATCAAATCTGAAGGCTGCAACCGCATGTCTTGCCGCTGTGGTGCCC
AGATGTGCTACCTCTGTCGAGTTTCTATTAATGGATATGACCATTTCTGCCAACATCCCCGCTCACCAGGAGCCCCTTGCCAGGAGTGTT
CAAGATGCTCTCTCTGGACCGATCCCACTGAAGATGATGAGAAGCTTATTGAGGAAATCCAGAAGGAGGCTGAAGAGGAACAGAAAAGAA
AGAATGGAGAGAACACCTTCAAACGCATTGGACCCCCGCTGGAGAAGCCTGTGGAGAAGGTGCAGAGGGTGGAGGCCCTCCCGAGGCCCG
TTCCGCAGAACCTGCCACAGCCACAGATGCCACCCTATGCCTTCGCGCACCCACCCTTCCCCCTGCCTCCCGTGCGGCCTGTGTTCAACA
ACTTCCCACTCAACATGGGGCCTATCCCAGCCCCGTACGTGCCCCCTCTGCCCAACGTGCGGGTCAACTATGACTTCGGTCCCATCCACA
TGCCCCTGGAGCACAACCTGCCCATGCACTTTGGCCCCCAGCCGCGGCATCGCTTCTGATGGCCCCGAATCCCCATTGAGCAGCACAAAG
CCCGTTTGGGGTAGGAGTGTGGATGGAGAACCCTCCCCCAAGGCTGGTGTCTGTACCATTGCATCCTAAGTCAGCTTGAAGGGTAGGCTG
GTTTTCTTCCCACCCCTTTCCTAGAAGGGCTACTGCTCCTGGAAGAGTGGACGGATCCATAATAAAGACGTCCCAAATGGTGGAGTTCGG
AGAGAGCTGCGATGTGAACTGCCCCTCCCCTCGCATCCCCCAGGCCACCAACGGCAGTCCTTCTGCCTTGTCCATGGCATAGGCCATAGA
CCAGGTCCCTGCTGCTCACACCTGGGCCTCTCCTCGGAGCCGACCCCTGGGTAGCAAGGCAGCCGAGAGCATCTCCCTGGAGGGGCCCAC
GGTTGGGCCAAGGGCAGAGGGGGCTGCACCTGCGGGCCTGGGAAGCATTGCTCAGGGTGGGGGGCTGGGACCATGGCCCGCAGAGGCACT
GCCACAGCTGTGAGGGCCAAGATGCTGTCCCCCCATCCAAAACCCGTGCGCCACTGCAGTGAGTGTTGAGGGCACCTCTCCTCCCCTCTT
ACACCTACTCAGATGAGGCAGCAGCAGACCCATCTCGCGGCGGGGGTTTTGTTCTGTTGCCGCCTAACTTTCTCATCCTCGGTCTCTGGA
AAGTCAGGCTGAGAAATCCTTTCCCAGGCCAGGCCGCTGCGGTACACTGGATGGTTCTGAAGCTGGCCCATTGAAAGAGCCTCTTAAGGC
AGCTGGGACAGAGGCCTGGTGGCCCTGCTGGGCAGCCCAACTGCTGGGGGAGACGTTTCTGCCACCCTGGGTGATGAGCAGCTTTTCCCC
CCTGGCTTTCTGGGGGAGGAGTGGGCCTCCTTAGGGAGACAGGTGACCCTGGGTGCCACCCCTGCCCCGTGTGTGCCCCGGGTGTTCTCA
GTGGTTGCTGAAGGCAGGTAGAGGGTGCTGTCCAGTATCCCCCATGTGAAGGTCACTTCCCTTCTCATGGAGTCAGCTGAGCATCAGCTC
AGCCCTGCCATGTCCCCACTCACCCTCCTCGCCTCCTGTCCGGCCCTGGGTTTCTAGCGGTGCCTGAGGCATCACTCTGGCCCATTGACA
GATGAGAGGTCTGAAGCCTTCCTGGCCACAGGCATCACTTTCTCCTCCTCCTCATGCCCTGCCTTGTCCTTGTCGTGTTGCCATGGGGTT
CTGAGAGGCTGGGAGTTCACAGACCTCAGACACAGCTGAGTCCGACAACCATTGGGGTGGGGCTGCATCAGTCTCCGGAGTGGCCCGCCA
CCTCCTGAAGCAGGGCCTGGCCCACCCAAGGTGCCTGGGGCAGGCGGGCACCGTCATTCGCTGCCATTGGCTTCTCAGATGTATTTCAAG
GACTAAAGTGGGCTCTAAGATCTAAGATGGCCCGGCGCGGTGGCTCCCGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATG
AGTTGAGGTCGGGAGTTTGAGTCCCCGTCTCTACTAAAAATACAAAATTAGCCGGACAAGGTGGCGCATGCCTATAATCCCAGGTACTCA
GGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGAGCAACAA
AAGCAAAACTCTATCTTTAAAAAAAAAAAAAAAAAAACTAAGATACCCATTCTTTCTGCCTTTGCCCAGGATGGAGGCTTTGAAGACAGG
TGGTCACCTGGACCTGGGGTAAGGGTGCGCAGGGAGGCCGGGCTTGGGGGCAGCCTGCTGCTATGTCCTTGCTGGCGCCCATACCTGTTG
GACTGCCTGAACTTTGCTACTAGCCTGAACGACAGTGCCTTGGAAAGGCAGGCTCCATGCGGCAGCAACAGGATTGTCTTCGGTACCTTA
AATATGCTCCCTGTGCTTCCCCAGGGAGGATCTCTGGGAGCAGAGGGCGGCTGTAGACATCACAGCTGAAGAGGTGACCTCAGGCCCTGG
GAGCCTCAGCTCCCTCTGCCCTGTACCCTAGGCACGTGGCTCCAGCAAGAGCCCCAGGCAGGACAAAGGGAGCAGGCAGCAGCTGCAGAA
ACAGCCCTAGACAGGTGCTGGCCTCAACCCTGGCAGGGGAGGGGGAGCCCAGAGTGATGTTTCTCCTAAGGCCAAACCCCAGGGGTGGGT
CATTTGAGAGGAGTTCCAGCTGTTCTGGCCACACTGGGCTGGTGGGGAAGGAGCGGCGGCCTCTTTCCTTGGAGGGTCCCTGATTCCTGA
GGATCCTCCCCGAGCCAGGCACGGGGGACCACAGGGCTGCCGTGAGCACCCACCCTGGTTCTCCAGGCCCCTCTGTCCAGAGGCAGGGCC
TGAACCTCGGGCTCCTGCCTGGACCAGTGACAGCATTGGGGAGAGAAGCACTGGGGGTCTTCAGACCAGCCAGCAAGGGGCCGTGCCAGT
GCCCAGAGAGCAGGTCAGACAACAGGCAACCCTGAGGCAGCTGGCTCCCTCTCTCTGCCCTGCAGGGCTTGCCGCAGGGCGTGAGGCTCC
CCAGCCACAGCCCCCTCTTACTTGCCTTAAAACTGGAGAGAGGAATCTAGTATTTGCACTTAGCAAAATATTTAAAAACTGAAAAAAATG
TGCATGATCTGTCACTTTGTATAAAAACAAGAAACGATTAGTTCATTAAACTTTTTCTTTACCTTCTGGTAGTAAAAATAGATAAAATAA

>92838_92838_8_TNRC18-RNF216_TNRC18_chr7_5410006_ENST00000430969_RNF216_chr7_5692141_ENST00000425013_length(amino acids)=1417AA_BP=
MIAALPRRMDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGEAFLGSFVASGMGPSASSH
GSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGA
PGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERL
SPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAAT
PAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPA
DAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHH
SRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPE
PAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLVDQERSLS
LSNVKGHGRADEDCVDDRARHREERLLGARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAHLATH
PWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPPLWPALYPPGRSP
LHHAQQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGP
AGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQ
ALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEV
EDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPE
TLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGM

--------------------------------------------------------------
>92838_92838_9_TNRC18-RNF216_TNRC18_chr7_5434071_ENST00000399537_RNF216_chr7_5663756_ENST00000389902_length(transcript)=1335nt_BP=692nt
GGCCGCGGGATGGCGGGCAGCAGGGGCGCCTAGCTGCGCCGGGAGCCGGGGCCGCCGCCGGAGTCGTTGTCGCCGGAGCCTGGAGCCGTG
AACCCAGCCGCGCCAGACGCCGTGTGCGCCGCCTCGCGCAGCTCCGCCTGGCCGCCCGGAGGGGCCCCACCGCCGGCCGCCTGTGCGCCC
CGGGCCGCGGGCCCGCCGCCGAGCGCAAGCCCCGCTGGCCGCCGCCATGCACGCCGCGGAGCCCCCGCCGCCCGAGGACTCTGGGACTAC
GCCGAGGCCGAACTTTTAGGTCCCACTGAGCTAGGCCTGCGGGCCGGGTGGGGGGCTGATCGCGGCACTCCCGCGGAGGATGGATGGCCG
AGACTTCGGGCCCCAGCGGTCCGTGCACGGTCCCCCGCCGCCGCTGCTGTCCGGCCTGGCCATGGACAGCCACCGCGTGGGCGCGGCCAC
TGCCGGACGCTTGCCCGCCTCGGGCTTGCCCGGCCCGCTGCCGCCCGGGAAGTACATGGCCGGCCTGAATCTCCATCCGCACCCGGGCGA
GGCCTTCTTGGGCAGCTTTGTGGCCAGCGGGATGGGGCCCTCGGCCTCGTCCCATGGGAGCCCAGTGCCACTGCCCTCTGACCTGTCTTT
CCGCTCCCCAACCCCTAGCAACCTGCCCATGGTGCAGCTGTGGGCCGCCCACGCCCATGAAGGAAGATGATGAGAAGCTTATTGAGGAAA
TCCAGAAGGAGGCTGAAGAGGAACAGAAAAGAAAGAATGGAGAGAACACCTTCAAACGCATTGGACCCCCGCTGGAGAAGCCTGTGGAGA
AGGTGCAGAGGGTGGAGGCCCTCCCGAGGCCCGTTCCGCAGAACCTGCCACAGCCACAGATGCCACCCTATGCCTTCGCGCACCCACCCT
TCCCCCTGCCTCCCGTGCGGCCTGTGTTCAACAACTTCCCACTCAACATGGGGCCTATCCCAGCCCCGTACGTGCCCCCTCTGCCCAACG
TGCGGGTCAACTATGACTTCGGTCCCATCCACATGCCCCTGGAGCACAACCTGCCCATGCACTTTGGCCCCCAGCCGCGGCATCGCTTCT
GATGGCCCCGAATCCCCATTGAGCAGCACAAAGCCCGTTTGGGGTAGGAGTGTGGATGGAGAACCCTCCCCCAAGGCTGGTGTCTGTACC
ATTGCATCCTAAGTCAGCTTGAAGGGTAGGCTGGTTTTCTTCCCACCCCTTTCCTAGAAGGGCTACTGCTCCTGGAAGAGTGGACGGATC

>92838_92838_9_TNRC18-RNF216_TNRC18_chr7_5434071_ENST00000399537_RNF216_chr7_5663756_ENST00000389902_length(amino acids)=195AA_BP=
MRREPGPPPESLSPEPGAVNPAAPDAVCAASRSSAWPPGGAPPPAACAPRAAGPPPSASPAGRRHARRGAPAARGLWDYAEAELLGPTEL
GLRAGWGADRGTPAEDGWPRLRAPAVRARSPAAAAVRPGHGQPPRGRGHCRTLARLGLARPAAAREVHGRPESPSAPGRGLLGQLCGQRD

--------------------------------------------------------------
>92838_92838_10_TNRC18-RNF216_TNRC18_chr7_5434071_ENST00000399537_RNF216_chr7_5663756_ENST00000425013_length(transcript)=3895nt_BP=692nt
GGCCGCGGGATGGCGGGCAGCAGGGGCGCCTAGCTGCGCCGGGAGCCGGGGCCGCCGCCGGAGTCGTTGTCGCCGGAGCCTGGAGCCGTG
AACCCAGCCGCGCCAGACGCCGTGTGCGCCGCCTCGCGCAGCTCCGCCTGGCCGCCCGGAGGGGCCCCACCGCCGGCCGCCTGTGCGCCC
CGGGCCGCGGGCCCGCCGCCGAGCGCAAGCCCCGCTGGCCGCCGCCATGCACGCCGCGGAGCCCCCGCCGCCCGAGGACTCTGGGACTAC
GCCGAGGCCGAACTTTTAGGTCCCACTGAGCTAGGCCTGCGGGCCGGGTGGGGGGCTGATCGCGGCACTCCCGCGGAGGATGGATGGCCG
AGACTTCGGGCCCCAGCGGTCCGTGCACGGTCCCCCGCCGCCGCTGCTGTCCGGCCTGGCCATGGACAGCCACCGCGTGGGCGCGGCCAC
TGCCGGACGCTTGCCCGCCTCGGGCTTGCCCGGCCCGCTGCCGCCCGGGAAGTACATGGCCGGCCTGAATCTCCATCCGCACCCGGGCGA
GGCCTTCTTGGGCAGCTTTGTGGCCAGCGGGATGGGGCCCTCGGCCTCGTCCCATGGGAGCCCAGTGCCACTGCCCTCTGACCTGTCTTT
CCGCTCCCCAACCCCTAGCAACCTGCCCATGGTGCAGCTGTGGGCCGCCCACGCCCATGAAGGAAGATGATGAGAAGCTTATTGAGGAAA
TCCAGAAGGAGGCTGAAGAGGAACAGAAAAGAAAGAATGGAGAGAACACCTTCAAACGCATTGGACCCCCGCTGGAGAAGCCTGTGGAGA
AGGTGCAGAGGGTGGAGGCCCTCCCGAGGCCCGTTCCGCAGAACCTGCCACAGCCACAGATGCCACCCTATGCCTTCGCGCACCCACCCT
TCCCCCTGCCTCCCGTGCGGCCTGTGTTCAACAACTTCCCACTCAACATGGGGCCTATCCCAGCCCCGTACGTGCCCCCTCTGCCCAACG
TGCGGGTCAACTATGACTTCGGTCCCATCCACATGCCCCTGGAGCACAACCTGCCCATGCACTTTGGCCCCCAGCCGCGGCATCGCTTCT
GATGGCCCCGAATCCCCATTGAGCAGCACAAAGCCCGTTTGGGGTAGGAGTGTGGATGGAGAACCCTCCCCCAAGGCTGGTGTCTGTACC
ATTGCATCCTAAGTCAGCTTGAAGGGTAGGCTGGTTTTCTTCCCACCCCTTTCCTAGAAGGGCTACTGCTCCTGGAAGAGTGGACGGATC
CATAATAAAGACGTCCCAAATGGTGGAGTTCGGAGAGAGCTGCGATGTGAACTGCCCCTCCCCTCGCATCCCCCAGGCCACCAACGGCAG
TCCTTCTGCCTTGTCCATGGCATAGGCCATAGACCAGGTCCCTGCTGCTCACACCTGGGCCTCTCCTCGGAGCCGACCCCTGGGTAGCAA
GGCAGCCGAGAGCATCTCCCTGGAGGGGCCCACGGTTGGGCCAAGGGCAGAGGGGGCTGCACCTGCGGGCCTGGGAAGCATTGCTCAGGG
TGGGGGGCTGGGACCATGGCCCGCAGAGGCACTGCCACAGCTGTGAGGGCCAAGATGCTGTCCCCCCATCCAAAACCCGTGCGCCACTGC
AGTGAGTGTTGAGGGCACCTCTCCTCCCCTCTTACACCTACTCAGATGAGGCAGCAGCAGACCCATCTCGCGGCGGGGGTTTTGTTCTGT
TGCCGCCTAACTTTCTCATCCTCGGTCTCTGGAAAGTCAGGCTGAGAAATCCTTTCCCAGGCCAGGCCGCTGCGGTACACTGGATGGTTC
TGAAGCTGGCCCATTGAAAGAGCCTCTTAAGGCAGCTGGGACAGAGGCCTGGTGGCCCTGCTGGGCAGCCCAACTGCTGGGGGAGACGTT
TCTGCCACCCTGGGTGATGAGCAGCTTTTCCCCCCTGGCTTTCTGGGGGAGGAGTGGGCCTCCTTAGGGAGACAGGTGACCCTGGGTGCC
ACCCCTGCCCCGTGTGTGCCCCGGGTGTTCTCAGTGGTTGCTGAAGGCAGGTAGAGGGTGCTGTCCAGTATCCCCCATGTGAAGGTCACT
TCCCTTCTCATGGAGTCAGCTGAGCATCAGCTCAGCCCTGCCATGTCCCCACTCACCCTCCTCGCCTCCTGTCCGGCCCTGGGTTTCTAG
CGGTGCCTGAGGCATCACTCTGGCCCATTGACAGATGAGAGGTCTGAAGCCTTCCTGGCCACAGGCATCACTTTCTCCTCCTCCTCATGC
CCTGCCTTGTCCTTGTCGTGTTGCCATGGGGTTCTGAGAGGCTGGGAGTTCACAGACCTCAGACACAGCTGAGTCCGACAACCATTGGGG
TGGGGCTGCATCAGTCTCCGGAGTGGCCCGCCACCTCCTGAAGCAGGGCCTGGCCCACCCAAGGTGCCTGGGGCAGGCGGGCACCGTCAT
TCGCTGCCATTGGCTTCTCAGATGTATTTCAAGGACTAAAGTGGGCTCTAAGATCTAAGATGGCCCGGCGCGGTGGCTCCCGCCTGTAAT
CCCAGCACTTTGGGAGGCCGAGGCGGGCGGATGAGTTGAGGTCGGGAGTTTGAGTCCCCGTCTCTACTAAAAATACAAAATTAGCCGGAC
AAGGTGGCGCATGCCTATAATCCCAGGTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCAA
GATTGTGCCACTGCACTCCAGCCTGAGCAACAAAAGCAAAACTCTATCTTTAAAAAAAAAAAAAAAAAAACTAAGATACCCATTCTTTCT
GCCTTTGCCCAGGATGGAGGCTTTGAAGACAGGTGGTCACCTGGACCTGGGGTAAGGGTGCGCAGGGAGGCCGGGCTTGGGGGCAGCCTG
CTGCTATGTCCTTGCTGGCGCCCATACCTGTTGGACTGCCTGAACTTTGCTACTAGCCTGAACGACAGTGCCTTGGAAAGGCAGGCTCCA
TGCGGCAGCAACAGGATTGTCTTCGGTACCTTAAATATGCTCCCTGTGCTTCCCCAGGGAGGATCTCTGGGAGCAGAGGGCGGCTGTAGA
CATCACAGCTGAAGAGGTGACCTCAGGCCCTGGGAGCCTCAGCTCCCTCTGCCCTGTACCCTAGGCACGTGGCTCCAGCAAGAGCCCCAG
GCAGGACAAAGGGAGCAGGCAGCAGCTGCAGAAACAGCCCTAGACAGGTGCTGGCCTCAACCCTGGCAGGGGAGGGGGAGCCCAGAGTGA
TGTTTCTCCTAAGGCCAAACCCCAGGGGTGGGTCATTTGAGAGGAGTTCCAGCTGTTCTGGCCACACTGGGCTGGTGGGGAAGGAGCGGC
GGCCTCTTTCCTTGGAGGGTCCCTGATTCCTGAGGATCCTCCCCGAGCCAGGCACGGGGGACCACAGGGCTGCCGTGAGCACCCACCCTG
GTTCTCCAGGCCCCTCTGTCCAGAGGCAGGGCCTGAACCTCGGGCTCCTGCCTGGACCAGTGACAGCATTGGGGAGAGAAGCACTGGGGG
TCTTCAGACCAGCCAGCAAGGGGCCGTGCCAGTGCCCAGAGAGCAGGTCAGACAACAGGCAACCCTGAGGCAGCTGGCTCCCTCTCTCTG
CCCTGCAGGGCTTGCCGCAGGGCGTGAGGCTCCCCAGCCACAGCCCCCTCTTACTTGCCTTAAAACTGGAGAGAGGAATCTAGTATTTGC
ACTTAGCAAAATATTTAAAAACTGAAAAAAATGTGCATGATCTGTCACTTTGTATAAAAACAAGAAACGATTAGTTCATTAAACTTTTTC
TTTACCTTCTGGTAGTAAAAATAGATAAAATAATTCCGTTTCAACTACTGTGTGTAAAAAGCCTGTATCATATGTAACTGGGACTTTTGT

>92838_92838_10_TNRC18-RNF216_TNRC18_chr7_5434071_ENST00000399537_RNF216_chr7_5663756_ENST00000425013_length(amino acids)=260AA_BP=7
MRLKVFSPFFLFCSSSASFWISSISFSSSSFMGVGGPQLHHGQVARGWGAERQVRGQWHWAPMGRGRGPHPAGHKAAQEGLARVRMEIQA
GHVLPGRQRAGQARGGQASGSGRAHAVAVHGQAGQQRRRGTVHGPLGPEVSAIHPPRECRDQPPTRPAGLAQWDLKVRPRRSPRVLGRRG

--------------------------------------------------------------
>92838_92838_11_TNRC18-RNF216_TNRC18_chr7_5434071_ENST00000430969_RNF216_chr7_5663756_ENST00000389902_length(transcript)=1335nt_BP=692nt
GGCCGCGGGATGGCGGGCAGCAGGGGCGCCTAGCTGCGCCGGGAGCCGGGGCCGCCGCCGGAGTCGTTGTCGCCGGAGCCTGGAGCCGTG
AACCCAGCCGCGCCAGACGCCGTGTGCGCCGCCTCGCGCAGCTCCGCCTGGCCGCCCGGAGGGGCCCCACCGCCGGCCGCCTGTGCGCCC
CGGGCCGCGGGCCCGCCGCCGAGCGCAAGCCCCGCTGGCCGCCGCCATGCACGCCGCGGAGCCCCCGCCGCCCGAGGACTCTGGGACTAC
GCCGAGGCCGAACTTTTAGGTCCCACTGAGCTAGGCCTGCGGGCCGGGTGGGGGGCTGATCGCGGCACTCCCGCGGAGGATGGATGGCCG
AGACTTCGGGCCCCAGCGGTCCGTGCACGGTCCCCCGCCGCCGCTGCTGTCCGGCCTGGCCATGGACAGCCACCGCGTGGGCGCGGCCAC
TGCCGGACGCTTGCCCGCCTCGGGCTTGCCCGGCCCGCTGCCGCCCGGGAAGTACATGGCCGGCCTGAATCTCCATCCGCACCCGGGCGA
GGCCTTCTTGGGCAGCTTTGTGGCCAGCGGGATGGGGCCCTCGGCCTCGTCCCATGGGAGCCCAGTGCCACTGCCCTCTGACCTGTCTTT
CCGCTCCCCAACCCCTAGCAACCTGCCCATGGTGCAGCTGTGGGCCGCCCACGCCCATGAAGGAAGATGATGAGAAGCTTATTGAGGAAA
TCCAGAAGGAGGCTGAAGAGGAACAGAAAAGAAAGAATGGAGAGAACACCTTCAAACGCATTGGACCCCCGCTGGAGAAGCCTGTGGAGA
AGGTGCAGAGGGTGGAGGCCCTCCCGAGGCCCGTTCCGCAGAACCTGCCACAGCCACAGATGCCACCCTATGCCTTCGCGCACCCACCCT
TCCCCCTGCCTCCCGTGCGGCCTGTGTTCAACAACTTCCCACTCAACATGGGGCCTATCCCAGCCCCGTACGTGCCCCCTCTGCCCAACG
TGCGGGTCAACTATGACTTCGGTCCCATCCACATGCCCCTGGAGCACAACCTGCCCATGCACTTTGGCCCCCAGCCGCGGCATCGCTTCT
GATGGCCCCGAATCCCCATTGAGCAGCACAAAGCCCGTTTGGGGTAGGAGTGTGGATGGAGAACCCTCCCCCAAGGCTGGTGTCTGTACC
ATTGCATCCTAAGTCAGCTTGAAGGGTAGGCTGGTTTTCTTCCCACCCCTTTCCTAGAAGGGCTACTGCTCCTGGAAGAGTGGACGGATC

>92838_92838_11_TNRC18-RNF216_TNRC18_chr7_5434071_ENST00000430969_RNF216_chr7_5663756_ENST00000389902_length(amino acids)=195AA_BP=
MRREPGPPPESLSPEPGAVNPAAPDAVCAASRSSAWPPGGAPPPAACAPRAAGPPPSASPAGRRHARRGAPAARGLWDYAEAELLGPTEL
GLRAGWGADRGTPAEDGWPRLRAPAVRARSPAAAAVRPGHGQPPRGRGHCRTLARLGLARPAAAREVHGRPESPSAPGRGLLGQLCGQRD

--------------------------------------------------------------
>92838_92838_12_TNRC18-RNF216_TNRC18_chr7_5434071_ENST00000430969_RNF216_chr7_5663756_ENST00000425013_length(transcript)=3895nt_BP=692nt
GGCCGCGGGATGGCGGGCAGCAGGGGCGCCTAGCTGCGCCGGGAGCCGGGGCCGCCGCCGGAGTCGTTGTCGCCGGAGCCTGGAGCCGTG
AACCCAGCCGCGCCAGACGCCGTGTGCGCCGCCTCGCGCAGCTCCGCCTGGCCGCCCGGAGGGGCCCCACCGCCGGCCGCCTGTGCGCCC
CGGGCCGCGGGCCCGCCGCCGAGCGCAAGCCCCGCTGGCCGCCGCCATGCACGCCGCGGAGCCCCCGCCGCCCGAGGACTCTGGGACTAC
GCCGAGGCCGAACTTTTAGGTCCCACTGAGCTAGGCCTGCGGGCCGGGTGGGGGGCTGATCGCGGCACTCCCGCGGAGGATGGATGGCCG
AGACTTCGGGCCCCAGCGGTCCGTGCACGGTCCCCCGCCGCCGCTGCTGTCCGGCCTGGCCATGGACAGCCACCGCGTGGGCGCGGCCAC
TGCCGGACGCTTGCCCGCCTCGGGCTTGCCCGGCCCGCTGCCGCCCGGGAAGTACATGGCCGGCCTGAATCTCCATCCGCACCCGGGCGA
GGCCTTCTTGGGCAGCTTTGTGGCCAGCGGGATGGGGCCCTCGGCCTCGTCCCATGGGAGCCCAGTGCCACTGCCCTCTGACCTGTCTTT
CCGCTCCCCAACCCCTAGCAACCTGCCCATGGTGCAGCTGTGGGCCGCCCACGCCCATGAAGGAAGATGATGAGAAGCTTATTGAGGAAA
TCCAGAAGGAGGCTGAAGAGGAACAGAAAAGAAAGAATGGAGAGAACACCTTCAAACGCATTGGACCCCCGCTGGAGAAGCCTGTGGAGA
AGGTGCAGAGGGTGGAGGCCCTCCCGAGGCCCGTTCCGCAGAACCTGCCACAGCCACAGATGCCACCCTATGCCTTCGCGCACCCACCCT
TCCCCCTGCCTCCCGTGCGGCCTGTGTTCAACAACTTCCCACTCAACATGGGGCCTATCCCAGCCCCGTACGTGCCCCCTCTGCCCAACG
TGCGGGTCAACTATGACTTCGGTCCCATCCACATGCCCCTGGAGCACAACCTGCCCATGCACTTTGGCCCCCAGCCGCGGCATCGCTTCT
GATGGCCCCGAATCCCCATTGAGCAGCACAAAGCCCGTTTGGGGTAGGAGTGTGGATGGAGAACCCTCCCCCAAGGCTGGTGTCTGTACC
ATTGCATCCTAAGTCAGCTTGAAGGGTAGGCTGGTTTTCTTCCCACCCCTTTCCTAGAAGGGCTACTGCTCCTGGAAGAGTGGACGGATC
CATAATAAAGACGTCCCAAATGGTGGAGTTCGGAGAGAGCTGCGATGTGAACTGCCCCTCCCCTCGCATCCCCCAGGCCACCAACGGCAG
TCCTTCTGCCTTGTCCATGGCATAGGCCATAGACCAGGTCCCTGCTGCTCACACCTGGGCCTCTCCTCGGAGCCGACCCCTGGGTAGCAA
GGCAGCCGAGAGCATCTCCCTGGAGGGGCCCACGGTTGGGCCAAGGGCAGAGGGGGCTGCACCTGCGGGCCTGGGAAGCATTGCTCAGGG
TGGGGGGCTGGGACCATGGCCCGCAGAGGCACTGCCACAGCTGTGAGGGCCAAGATGCTGTCCCCCCATCCAAAACCCGTGCGCCACTGC
AGTGAGTGTTGAGGGCACCTCTCCTCCCCTCTTACACCTACTCAGATGAGGCAGCAGCAGACCCATCTCGCGGCGGGGGTTTTGTTCTGT
TGCCGCCTAACTTTCTCATCCTCGGTCTCTGGAAAGTCAGGCTGAGAAATCCTTTCCCAGGCCAGGCCGCTGCGGTACACTGGATGGTTC
TGAAGCTGGCCCATTGAAAGAGCCTCTTAAGGCAGCTGGGACAGAGGCCTGGTGGCCCTGCTGGGCAGCCCAACTGCTGGGGGAGACGTT
TCTGCCACCCTGGGTGATGAGCAGCTTTTCCCCCCTGGCTTTCTGGGGGAGGAGTGGGCCTCCTTAGGGAGACAGGTGACCCTGGGTGCC
ACCCCTGCCCCGTGTGTGCCCCGGGTGTTCTCAGTGGTTGCTGAAGGCAGGTAGAGGGTGCTGTCCAGTATCCCCCATGTGAAGGTCACT
TCCCTTCTCATGGAGTCAGCTGAGCATCAGCTCAGCCCTGCCATGTCCCCACTCACCCTCCTCGCCTCCTGTCCGGCCCTGGGTTTCTAG
CGGTGCCTGAGGCATCACTCTGGCCCATTGACAGATGAGAGGTCTGAAGCCTTCCTGGCCACAGGCATCACTTTCTCCTCCTCCTCATGC
CCTGCCTTGTCCTTGTCGTGTTGCCATGGGGTTCTGAGAGGCTGGGAGTTCACAGACCTCAGACACAGCTGAGTCCGACAACCATTGGGG
TGGGGCTGCATCAGTCTCCGGAGTGGCCCGCCACCTCCTGAAGCAGGGCCTGGCCCACCCAAGGTGCCTGGGGCAGGCGGGCACCGTCAT
TCGCTGCCATTGGCTTCTCAGATGTATTTCAAGGACTAAAGTGGGCTCTAAGATCTAAGATGGCCCGGCGCGGTGGCTCCCGCCTGTAAT
CCCAGCACTTTGGGAGGCCGAGGCGGGCGGATGAGTTGAGGTCGGGAGTTTGAGTCCCCGTCTCTACTAAAAATACAAAATTAGCCGGAC
AAGGTGGCGCATGCCTATAATCCCAGGTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCAA
GATTGTGCCACTGCACTCCAGCCTGAGCAACAAAAGCAAAACTCTATCTTTAAAAAAAAAAAAAAAAAAACTAAGATACCCATTCTTTCT
GCCTTTGCCCAGGATGGAGGCTTTGAAGACAGGTGGTCACCTGGACCTGGGGTAAGGGTGCGCAGGGAGGCCGGGCTTGGGGGCAGCCTG
CTGCTATGTCCTTGCTGGCGCCCATACCTGTTGGACTGCCTGAACTTTGCTACTAGCCTGAACGACAGTGCCTTGGAAAGGCAGGCTCCA
TGCGGCAGCAACAGGATTGTCTTCGGTACCTTAAATATGCTCCCTGTGCTTCCCCAGGGAGGATCTCTGGGAGCAGAGGGCGGCTGTAGA
CATCACAGCTGAAGAGGTGACCTCAGGCCCTGGGAGCCTCAGCTCCCTCTGCCCTGTACCCTAGGCACGTGGCTCCAGCAAGAGCCCCAG
GCAGGACAAAGGGAGCAGGCAGCAGCTGCAGAAACAGCCCTAGACAGGTGCTGGCCTCAACCCTGGCAGGGGAGGGGGAGCCCAGAGTGA
TGTTTCTCCTAAGGCCAAACCCCAGGGGTGGGTCATTTGAGAGGAGTTCCAGCTGTTCTGGCCACACTGGGCTGGTGGGGAAGGAGCGGC
GGCCTCTTTCCTTGGAGGGTCCCTGATTCCTGAGGATCCTCCCCGAGCCAGGCACGGGGGACCACAGGGCTGCCGTGAGCACCCACCCTG
GTTCTCCAGGCCCCTCTGTCCAGAGGCAGGGCCTGAACCTCGGGCTCCTGCCTGGACCAGTGACAGCATTGGGGAGAGAAGCACTGGGGG
TCTTCAGACCAGCCAGCAAGGGGCCGTGCCAGTGCCCAGAGAGCAGGTCAGACAACAGGCAACCCTGAGGCAGCTGGCTCCCTCTCTCTG
CCCTGCAGGGCTTGCCGCAGGGCGTGAGGCTCCCCAGCCACAGCCCCCTCTTACTTGCCTTAAAACTGGAGAGAGGAATCTAGTATTTGC
ACTTAGCAAAATATTTAAAAACTGAAAAAAATGTGCATGATCTGTCACTTTGTATAAAAACAAGAAACGATTAGTTCATTAAACTTTTTC
TTTACCTTCTGGTAGTAAAAATAGATAAAATAATTCCGTTTCAACTACTGTGTGTAAAAAGCCTGTATCATATGTAACTGGGACTTTTGT

>92838_92838_12_TNRC18-RNF216_TNRC18_chr7_5434071_ENST00000430969_RNF216_chr7_5663756_ENST00000425013_length(amino acids)=260AA_BP=7
MRLKVFSPFFLFCSSSASFWISSISFSSSSFMGVGGPQLHHGQVARGWGAERQVRGQWHWAPMGRGRGPHPAGHKAAQEGLARVRMEIQA
GHVLPGRQRAGQARGGQASGSGRAHAVAVHGQAGQQRRRGTVHGPLGPEVSAIHPPRECRDQPPTRPAGLAQWDLKVRPRRSPRVLGRRG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TNRC18-RNF216


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TNRC18-RNF216


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TNRC18-RNF216


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource