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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TNRC6B-ADSL (FusionGDB2 ID:92858)

Fusion Gene Summary for TNRC6B-ADSL

check button Fusion gene summary
Fusion gene informationFusion gene name: TNRC6B-ADSL
Fusion gene ID: 92858
HgeneTgene
Gene symbol

TNRC6B

ADSL

Gene ID

23112

158

Gene nametrinucleotide repeat containing adaptor 6Badenylosuccinate lyase
Synonyms-AMPS|ASASE|ASL
Cytomap

22q13.1

22q13.1

Type of geneprotein-codingprotein-coding
Descriptiontrinucleotide repeat-containing gene 6B proteintrinucleotide repeat containing 6Badenylosuccinate lyaseadenylosuccinase
Modification date2020031320200315
UniProtAcc.

P30566

Ensembl transtripts involved in fusion geneENST00000301923, ENST00000335727, 
ENST00000402203, ENST00000454349, 
ENST00000497559, 		ENST00000342312, 
ENST00000454266, ENST00000480775, 
ENST00000216194, 
Fusion gene scores* DoF score36 X 24 X 16=138245 X 8 X 5=200
# samples 437
** MAII scorelog2(43/13824*10)=-5.00669465257401
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/200*10)=-1.51457317282976
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TNRC6B [Title/Abstract] AND ADSL [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTNRC6B(40552186)-ADSL(40754867), # samples:1
TNRC6B(40552186)-ADSL(40749076), # samples:1
TNRC6B(40441002)-ADSL(40760280), # samples:1
TNRC6B(40574144)-ADSL(40754868), # samples:1
TNRC6B(40552186)-ADSL(40754868), # samples:1
Anticipated loss of major functional domain due to fusion event.TNRC6B-ADSL seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
TNRC6B-ADSL seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
TNRC6B-ADSL seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneADSL

GO:0006167

AMP biosynthetic process

11428554


check buttonFusion gene breakpoints across TNRC6B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ADSL (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-DD-AAE2TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
ChimerDB4STADTCGA-VQ-AA69-01ATNRC6Bchr22

40552186

+ADSLchr22

40754868

+
ChimerDB4STADTCGA-VQ-AA69-01ATNRC6Bchr22

40574144

+ADSLchr22

40754868

+
ChimerDB4STADTCGA-VQ-AA69TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
ChimerDB4STADTCGA-VQ-AA69TNRC6Bchr22

40552186

+ADSLchr22

40754867

+


Top

Fusion Gene ORF analysis for TNRC6B-ADSL

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000301923ENST00000342312TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
5CDS-intronENST00000301923ENST00000454266TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
5CDS-intronENST00000301923ENST00000480775TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
5CDS-intronENST00000301923ENST00000480775TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
5CDS-intronENST00000301923ENST00000480775TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
5CDS-intronENST00000335727ENST00000480775TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
5CDS-intronENST00000402203ENST00000342312TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
5CDS-intronENST00000402203ENST00000454266TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
5CDS-intronENST00000402203ENST00000480775TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
5CDS-intronENST00000402203ENST00000480775TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
5CDS-intronENST00000402203ENST00000480775TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
5CDS-intronENST00000454349ENST00000480775TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
5UTR-3CDSENST00000301923ENST00000216194TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
5UTR-3CDSENST00000301923ENST00000342312TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
5UTR-3CDSENST00000301923ENST00000454266TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
5UTR-intronENST00000301923ENST00000480775TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
Frame-shiftENST00000301923ENST00000216194TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
Frame-shiftENST00000402203ENST00000216194TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
In-frameENST00000301923ENST00000216194TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
In-frameENST00000301923ENST00000216194TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
In-frameENST00000301923ENST00000342312TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
In-frameENST00000301923ENST00000342312TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
In-frameENST00000301923ENST00000454266TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
In-frameENST00000301923ENST00000454266TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
In-frameENST00000335727ENST00000216194TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
In-frameENST00000335727ENST00000342312TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
In-frameENST00000335727ENST00000454266TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
In-frameENST00000402203ENST00000216194TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
In-frameENST00000402203ENST00000216194TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
In-frameENST00000402203ENST00000342312TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
In-frameENST00000402203ENST00000342312TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
In-frameENST00000402203ENST00000454266TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
In-frameENST00000402203ENST00000454266TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
In-frameENST00000454349ENST00000216194TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
In-frameENST00000454349ENST00000342312TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
In-frameENST00000454349ENST00000454266TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
intron-3CDSENST00000301923ENST00000216194TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
intron-3CDSENST00000301923ENST00000342312TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
intron-3CDSENST00000301923ENST00000454266TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
intron-3CDSENST00000335727ENST00000216194TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-3CDSENST00000335727ENST00000216194TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
intron-3CDSENST00000335727ENST00000216194TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
intron-3CDSENST00000335727ENST00000216194TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
intron-3CDSENST00000335727ENST00000342312TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-3CDSENST00000335727ENST00000342312TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
intron-3CDSENST00000335727ENST00000342312TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
intron-3CDSENST00000335727ENST00000454266TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-3CDSENST00000335727ENST00000454266TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
intron-3CDSENST00000335727ENST00000454266TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
intron-3CDSENST00000402203ENST00000216194TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-3CDSENST00000402203ENST00000216194TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
intron-3CDSENST00000402203ENST00000342312TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-3CDSENST00000402203ENST00000342312TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
intron-3CDSENST00000402203ENST00000454266TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-3CDSENST00000402203ENST00000454266TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
intron-3CDSENST00000454349ENST00000216194TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-3CDSENST00000454349ENST00000216194TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
intron-3CDSENST00000454349ENST00000216194TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
intron-3CDSENST00000454349ENST00000216194TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
intron-3CDSENST00000454349ENST00000342312TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-3CDSENST00000454349ENST00000342312TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
intron-3CDSENST00000454349ENST00000342312TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
intron-3CDSENST00000454349ENST00000454266TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-3CDSENST00000454349ENST00000454266TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
intron-3CDSENST00000454349ENST00000454266TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
intron-3CDSENST00000497559ENST00000216194TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-3CDSENST00000497559ENST00000216194TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
intron-3CDSENST00000497559ENST00000216194TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
intron-3CDSENST00000497559ENST00000216194TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
intron-3CDSENST00000497559ENST00000216194TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
intron-3CDSENST00000497559ENST00000342312TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-3CDSENST00000497559ENST00000342312TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
intron-3CDSENST00000497559ENST00000342312TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
intron-3CDSENST00000497559ENST00000342312TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
intron-3CDSENST00000497559ENST00000454266TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-3CDSENST00000497559ENST00000454266TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
intron-3CDSENST00000497559ENST00000454266TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
intron-3CDSENST00000497559ENST00000454266TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
intron-intronENST00000301923ENST00000480775TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
intron-intronENST00000335727ENST00000342312TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
intron-intronENST00000335727ENST00000454266TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
intron-intronENST00000335727ENST00000480775TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-intronENST00000335727ENST00000480775TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
intron-intronENST00000335727ENST00000480775TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
intron-intronENST00000335727ENST00000480775TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
intron-intronENST00000402203ENST00000480775TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-intronENST00000402203ENST00000480775TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
intron-intronENST00000454349ENST00000342312TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
intron-intronENST00000454349ENST00000454266TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
intron-intronENST00000454349ENST00000480775TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-intronENST00000454349ENST00000480775TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
intron-intronENST00000454349ENST00000480775TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
intron-intronENST00000454349ENST00000480775TNRC6Bchr22

40552186

+ADSLchr22

40754867

+
intron-intronENST00000497559ENST00000342312TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
intron-intronENST00000497559ENST00000454266TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
intron-intronENST00000497559ENST00000480775TNRC6Bchr22

40441002

+ADSLchr22

40760280

+
intron-intronENST00000497559ENST00000480775TNRC6Bchr22

40552186

+ADSLchr22

40754868

+
intron-intronENST00000497559ENST00000480775TNRC6Bchr22

40574144

+ADSLchr22

40754868

+
intron-intronENST00000497559ENST00000480775TNRC6Bchr22

40552186

+ADSLchr22

40749076

+
intron-intronENST00000497559ENST00000480775TNRC6Bchr22

40552186

+ADSLchr22

40754867

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000301923TNRC6Bchr2240552186+ENST00000216194ADSLchr2240754867+18704152301387385
ENST00000301923TNRC6Bchr2240552186+ENST00000454266ADSLchr2240754867+14804152301387385
ENST00000301923TNRC6Bchr2240552186+ENST00000342312ADSLchr2240754867+16854152301210326
ENST00000402203TNRC6Bchr2240552186+ENST00000216194ADSLchr2240754867+18033481631320385
ENST00000402203TNRC6Bchr2240552186+ENST00000454266ADSLchr2240754867+14133481631320385
ENST00000402203TNRC6Bchr2240552186+ENST00000342312ADSLchr2240754867+16183481631143326
ENST00000454349TNRC6Bchr2240574144+ENST00000216194ADSLchr2240754868+16712161991188329
ENST00000454349TNRC6Bchr2240574144+ENST00000454266ADSLchr2240754868+12812161991188329
ENST00000454349TNRC6Bchr2240574144+ENST00000342312ADSLchr2240754868+14862161991011270
ENST00000335727TNRC6Bchr2240574144+ENST00000216194ADSLchr2240754868+16541991821171329
ENST00000335727TNRC6Bchr2240574144+ENST00000454266ADSLchr2240754868+12641991821171329
ENST00000335727TNRC6Bchr2240574144+ENST00000342312ADSLchr2240754868+1469199182994270
ENST00000301923TNRC6Bchr2240552186+ENST00000216194ADSLchr2240754868+18704152301387385
ENST00000301923TNRC6Bchr2240552186+ENST00000454266ADSLchr2240754868+14804152301387385
ENST00000301923TNRC6Bchr2240552186+ENST00000342312ADSLchr2240754868+16854152301210326
ENST00000402203TNRC6Bchr2240552186+ENST00000216194ADSLchr2240754868+18033481631320385
ENST00000402203TNRC6Bchr2240552186+ENST00000454266ADSLchr2240754868+14133481631320385
ENST00000402203TNRC6Bchr2240552186+ENST00000342312ADSLchr2240754868+16183481631143326

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000301923ENST00000216194TNRC6Bchr2240552186+ADSLchr2240754867+0.0018191660.99818087
ENST00000301923ENST00000454266TNRC6Bchr2240552186+ADSLchr2240754867+0.0034770540.996523
ENST00000301923ENST00000342312TNRC6Bchr2240552186+ADSLchr2240754867+0.0022671750.99773276
ENST00000402203ENST00000216194TNRC6Bchr2240552186+ADSLchr2240754867+0.0022904870.9977095
ENST00000402203ENST00000454266TNRC6Bchr2240552186+ADSLchr2240754867+0.0039720360.99602795
ENST00000402203ENST00000342312TNRC6Bchr2240552186+ADSLchr2240754867+0.002888650.9971113
ENST00000454349ENST00000216194TNRC6Bchr2240574144+ADSLchr2240754868+0.0004243150.9995757
ENST00000454349ENST00000454266TNRC6Bchr2240574144+ADSLchr2240754868+0.0008965590.99910337
ENST00000454349ENST00000342312TNRC6Bchr2240574144+ADSLchr2240754868+0.0009525150.99904746
ENST00000335727ENST00000216194TNRC6Bchr2240574144+ADSLchr2240754868+0.0004015740.99959844
ENST00000335727ENST00000454266TNRC6Bchr2240574144+ADSLchr2240754868+0.0009154560.9990846
ENST00000335727ENST00000342312TNRC6Bchr2240574144+ADSLchr2240754868+0.0008718270.99912816
ENST00000301923ENST00000216194TNRC6Bchr2240552186+ADSLchr2240754868+0.0018191660.99818087
ENST00000301923ENST00000454266TNRC6Bchr2240552186+ADSLchr2240754868+0.0034770540.996523
ENST00000301923ENST00000342312TNRC6Bchr2240552186+ADSLchr2240754868+0.0022671750.99773276
ENST00000402203ENST00000216194TNRC6Bchr2240552186+ADSLchr2240754868+0.0022904870.9977095
ENST00000402203ENST00000454266TNRC6Bchr2240552186+ADSLchr2240754868+0.0039720360.99602795
ENST00000402203ENST00000342312TNRC6Bchr2240552186+ADSLchr2240754868+0.002888650.9971113

Top

Fusion Genomic Features for TNRC6B-ADSL


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TNRC6Bchr2240574144+ADSLchr2240754867+1.06E-070.9999999
TNRC6Bchr2240552186+ADSLchr2240754867+2.50E-121
TNRC6Bchr2240552186+ADSLchr2240749076+3.33E-111
TNRC6Bchr2240441002+ADSLchr2240760279+2.56E-081
TNRC6Bchr2240552186+ADSLchr2240754867+2.50E-121
TNRC6Bchr2240574144+ADSLchr2240754867+1.06E-070.9999999
TNRC6Bchr2240552186+ADSLchr2240754867+2.50E-121
TNRC6Bchr2240552186+ADSLchr2240749076+3.33E-111
TNRC6Bchr2240441002+ADSLchr2240760279+2.56E-081
TNRC6Bchr2240552186+ADSLchr2240754867+2.50E-121

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for TNRC6B-ADSL


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:40552186/chr22:40754867)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ADSL

P30566

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate. {ECO:0000269|PubMed:10888601}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000301923+4241_39371030.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000402203+4241_39371030.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000301923+4241_39371030.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000402203+4241_39371030.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000335727+1211_3901724.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000454349+1231_3901834.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000335727+1211_3901724.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000454349+1231_3901834.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000301923+1241_3901030.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000335727+1211_3911724.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000402203+1241_3901030.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000454349+1231_3911834.0Coiled coilOntology_term=ECO:0000255
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000301923+4241150_1220371030.0Compositional biasNote=Gln-rich
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000301923+424825_880371030.0Compositional biasNote=Pro-rich
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000335727+1211150_122001724.0Compositional biasNote=Gln-rich
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000335727+121825_88001724.0Compositional biasNote=Pro-rich
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000402203+4241150_1220371030.0Compositional biasNote=Gln-rich
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000402203+424825_880371030.0Compositional biasNote=Pro-rich
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000454349+1231150_122001834.0Compositional biasNote=Gln-rich
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000454349+123825_88001834.0Compositional biasNote=Pro-rich
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000301923+4241150_1220371030.0Compositional biasNote=Gln-rich
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000301923+424825_880371030.0Compositional biasNote=Pro-rich
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000335727+1211150_122001724.0Compositional biasNote=Gln-rich
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000335727+121825_88001724.0Compositional biasNote=Pro-rich
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000402203+4241150_1220371030.0Compositional biasNote=Gln-rich
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000402203+424825_880371030.0Compositional biasNote=Pro-rich
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000454349+1231150_122001834.0Compositional biasNote=Gln-rich
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000454349+123825_88001834.0Compositional biasNote=Pro-rich
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000301923+1241150_122001030.0Compositional biasNote=Gln-rich
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000301923+124825_88001030.0Compositional biasNote=Pro-rich
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000335727+1211150_122011724.0Compositional biasNote=Gln-rich
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000335727+121825_88011724.0Compositional biasNote=Pro-rich
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000402203+1241150_122001030.0Compositional biasNote=Gln-rich
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000402203+124825_88001030.0Compositional biasNote=Pro-rich
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000454349+1231150_122011834.0Compositional biasNote=Gln-rich
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000454349+123825_88011834.0Compositional biasNote=Pro-rich
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000301923+4241648_1720371030.0DomainNote=RRM
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000335727+1211648_172001724.0DomainNote=RRM
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000402203+4241648_1720371030.0DomainNote=RRM
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000454349+1231648_172001834.0DomainNote=RRM
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000301923+4241648_1720371030.0DomainNote=RRM
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000335727+1211648_172001724.0DomainNote=RRM
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000402203+4241648_1720371030.0DomainNote=RRM
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000454349+1231648_172001834.0DomainNote=RRM
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000301923+1241648_172001030.0DomainNote=RRM
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000335727+1211648_172011724.0DomainNote=RRM
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000402203+1241648_172001030.0DomainNote=RRM
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000454349+1231648_172011834.0DomainNote=RRM
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000301923+4241472_1490371030.0RegionNote=PABPC1-interacting motif-2 (PAM2)
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000335727+1211472_149001724.0RegionNote=PABPC1-interacting motif-2 (PAM2)
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000402203+4241472_1490371030.0RegionNote=PABPC1-interacting motif-2 (PAM2)
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000454349+1231472_149001834.0RegionNote=PABPC1-interacting motif-2 (PAM2)
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000301923+4241472_1490371030.0RegionNote=PABPC1-interacting motif-2 (PAM2)
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000335727+1211472_149001724.0RegionNote=PABPC1-interacting motif-2 (PAM2)
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000402203+4241472_1490371030.0RegionNote=PABPC1-interacting motif-2 (PAM2)
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000454349+1231472_149001834.0RegionNote=PABPC1-interacting motif-2 (PAM2)
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000301923+1241472_149001030.0RegionNote=PABPC1-interacting motif-2 (PAM2)
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000335727+1211472_149011724.0RegionNote=PABPC1-interacting motif-2 (PAM2)
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000402203+1241472_149001030.0RegionNote=PABPC1-interacting motif-2 (PAM2)
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000454349+1231472_149011834.0RegionNote=PABPC1-interacting motif-2 (PAM2)
TgeneADSLchr22:40552186chr22:40754867ENST00000216194313111_112160485.0RegionNote=Substrate binding
TgeneADSLchr22:40552186chr22:40754867ENST0000021619431320_21160485.0RegionNote=Substrate binding%3B shared with neighboring subunit
TgeneADSLchr22:40552186chr22:40754867ENST0000021619431385_87160485.0RegionNote=Substrate binding
TgeneADSLchr22:40552186chr22:40754867ENST00000342312312111_112160426.0RegionNote=Substrate binding
TgeneADSLchr22:40552186chr22:40754867ENST0000034231231220_21160426.0RegionNote=Substrate binding%3B shared with neighboring subunit
TgeneADSLchr22:40552186chr22:40754867ENST0000034231231285_87160426.0RegionNote=Substrate binding
TgeneADSLchr22:40552186chr22:40754868ENST00000216194313111_112160485.0RegionNote=Substrate binding
TgeneADSLchr22:40552186chr22:40754868ENST0000021619431320_21160485.0RegionNote=Substrate binding%3B shared with neighboring subunit
TgeneADSLchr22:40552186chr22:40754868ENST0000021619431385_87160485.0RegionNote=Substrate binding
TgeneADSLchr22:40552186chr22:40754868ENST00000342312312111_112160426.0RegionNote=Substrate binding
TgeneADSLchr22:40552186chr22:40754868ENST0000034231231220_21160426.0RegionNote=Substrate binding%3B shared with neighboring subunit
TgeneADSLchr22:40552186chr22:40754868ENST0000034231231285_87160426.0RegionNote=Substrate binding
TgeneADSLchr22:40574144chr22:40754868ENST00000216194313111_112160485.0RegionNote=Substrate binding
TgeneADSLchr22:40574144chr22:40754868ENST0000021619431320_21160485.0RegionNote=Substrate binding%3B shared with neighboring subunit
TgeneADSLchr22:40574144chr22:40754868ENST0000021619431385_87160485.0RegionNote=Substrate binding
TgeneADSLchr22:40574144chr22:40754868ENST00000342312312111_112160426.0RegionNote=Substrate binding
TgeneADSLchr22:40574144chr22:40754868ENST0000034231231220_21160426.0RegionNote=Substrate binding%3B shared with neighboring subunit
TgeneADSLchr22:40574144chr22:40754868ENST0000034231231285_87160426.0RegionNote=Substrate binding


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Fusion Gene Sequence for TNRC6B-ADSL


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>92858_92858_1_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000301923_ADSL_chr22_40754867_ENST00000216194_length(transcript)=1870nt_BP=415nt
TTGTTTATTTTGTTTTTAGTTTTTGGGGTCCCCGTGCTGCTGCAAGGCGAAACGGGAGGGAGTGACCCCTGCGCCCCTCAGTCCCCCCTA
CGACGTCGCCTCCATAGTCTGCGGAGAAGCGGAGACTGCGCGCCTCGCCTCACAGCGAAACGCCGCGCACTCGGAGCCGGCACGGCTCGG
CGGGTTGTGGTTTTTTGCACTGAATGTAACCTAGACTCATCTTCACGGGCTTGTGTTGCCCCAGGTACTGTCAAAGGCAGTATTTTTGTG
TTTCTGCAGAGTTTTGCACAAAATCTGTTCCCATGCAAACCAATGAGGGAGAAGTATCGGAAGAAAGCAGTTCCAAGGTGGAACAGGAGG
ATTTTGTAATGGAAGGGCATGGCAAGACTCCACCTCCTGGTGAAGAAAGCAAACAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCT
GTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTG
GCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTA
AGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGC
ACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGC
CATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCAT
CTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGA
ATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAG
AGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTG
TGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATT
TACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATG
AAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAAT
TGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCT
CAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTG
TTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTG
TCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATT

>92858_92858_1_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000301923_ADSL_chr22_40754867_ENST00000216194_length(amino acids)=385AA_BP=1
MCCPRYCQRQYFCVSAEFCTKSVPMQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQPAQLTTVGKRCCLWIQDLCMDLQNLKRV
RDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEME
EPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVI
ERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQR

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>92858_92858_2_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000301923_ADSL_chr22_40754867_ENST00000342312_length(transcript)=1685nt_BP=415nt
TTGTTTATTTTGTTTTTAGTTTTTGGGGTCCCCGTGCTGCTGCAAGGCGAAACGGGAGGGAGTGACCCCTGCGCCCCTCAGTCCCCCCTA
CGACGTCGCCTCCATAGTCTGCGGAGAAGCGGAGACTGCGCGCCTCGCCTCACAGCGAAACGCCGCGCACTCGGAGCCGGCACGGCTCGG
CGGGTTGTGGTTTTTTGCACTGAATGTAACCTAGACTCATCTTCACGGGCTTGTGTTGCCCCAGGTACTGTCAAAGGCAGTATTTTTGTG
TTTCTGCAGAGTTTTGCACAAAATCTGTTCCCATGCAAACCAATGAGGGAGAAGTATCGGAAGAAAGCAGTTCCAAGGTGGAACAGGAGG
ATTTTGTAATGGAAGGGCATGGCAAGACTCCACCTCCTGGTGAAGAAAGCAAACAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCT
GTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTG
GCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTA
AGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGC
ACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGC
CATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCAT
CTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGA
ATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAG
AGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCAT
ATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAA
AATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTT
TCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCT
CTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTC
CTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTT

>92858_92858_2_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000301923_ADSL_chr22_40754867_ENST00000342312_length(amino acids)=326AA_BP=1
MCCPRYCQRQYFCVSAEFCTKSVPMQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQPAQLTTVGKRCCLWIQDLCMDLQNLKRV
RDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEME
EPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVI

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>92858_92858_3_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000301923_ADSL_chr22_40754867_ENST00000454266_length(transcript)=1480nt_BP=415nt
TTGTTTATTTTGTTTTTAGTTTTTGGGGTCCCCGTGCTGCTGCAAGGCGAAACGGGAGGGAGTGACCCCTGCGCCCCTCAGTCCCCCCTA
CGACGTCGCCTCCATAGTCTGCGGAGAAGCGGAGACTGCGCGCCTCGCCTCACAGCGAAACGCCGCGCACTCGGAGCCGGCACGGCTCGG
CGGGTTGTGGTTTTTTGCACTGAATGTAACCTAGACTCATCTTCACGGGCTTGTGTTGCCCCAGGTACTGTCAAAGGCAGTATTTTTGTG
TTTCTGCAGAGTTTTGCACAAAATCTGTTCCCATGCAAACCAATGAGGGAGAAGTATCGGAAGAAAGCAGTTCCAAGGTGGAACAGGAGG
ATTTTGTAATGGAAGGGCATGGCAAGACTCCACCTCCTGGTGAAGAAAGCAAACAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCT
GTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTG
GCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTA
AGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGC
ACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGC
CATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCAT
CTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGA
ATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAG
AGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTG
TGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATT
TACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATG
AAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAAT

>92858_92858_3_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000301923_ADSL_chr22_40754867_ENST00000454266_length(amino acids)=385AA_BP=1
MCCPRYCQRQYFCVSAEFCTKSVPMQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQPAQLTTVGKRCCLWIQDLCMDLQNLKRV
RDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEME
EPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVI
ERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQR

--------------------------------------------------------------
>92858_92858_4_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000301923_ADSL_chr22_40754868_ENST00000216194_length(transcript)=1870nt_BP=415nt
TTGTTTATTTTGTTTTTAGTTTTTGGGGTCCCCGTGCTGCTGCAAGGCGAAACGGGAGGGAGTGACCCCTGCGCCCCTCAGTCCCCCCTA
CGACGTCGCCTCCATAGTCTGCGGAGAAGCGGAGACTGCGCGCCTCGCCTCACAGCGAAACGCCGCGCACTCGGAGCCGGCACGGCTCGG
CGGGTTGTGGTTTTTTGCACTGAATGTAACCTAGACTCATCTTCACGGGCTTGTGTTGCCCCAGGTACTGTCAAAGGCAGTATTTTTGTG
TTTCTGCAGAGTTTTGCACAAAATCTGTTCCCATGCAAACCAATGAGGGAGAAGTATCGGAAGAAAGCAGTTCCAAGGTGGAACAGGAGG
ATTTTGTAATGGAAGGGCATGGCAAGACTCCACCTCCTGGTGAAGAAAGCAAACAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCT
GTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTG
GCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTA
AGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGC
ACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGC
CATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCAT
CTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGA
ATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAG
AGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTG
TGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATT
TACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATG
AAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAAT
TGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCT
CAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTG
TTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTG
TCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATT

>92858_92858_4_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000301923_ADSL_chr22_40754868_ENST00000216194_length(amino acids)=385AA_BP=1
MCCPRYCQRQYFCVSAEFCTKSVPMQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQPAQLTTVGKRCCLWIQDLCMDLQNLKRV
RDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEME
EPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVI
ERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQR

--------------------------------------------------------------
>92858_92858_5_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000301923_ADSL_chr22_40754868_ENST00000342312_length(transcript)=1685nt_BP=415nt
TTGTTTATTTTGTTTTTAGTTTTTGGGGTCCCCGTGCTGCTGCAAGGCGAAACGGGAGGGAGTGACCCCTGCGCCCCTCAGTCCCCCCTA
CGACGTCGCCTCCATAGTCTGCGGAGAAGCGGAGACTGCGCGCCTCGCCTCACAGCGAAACGCCGCGCACTCGGAGCCGGCACGGCTCGG
CGGGTTGTGGTTTTTTGCACTGAATGTAACCTAGACTCATCTTCACGGGCTTGTGTTGCCCCAGGTACTGTCAAAGGCAGTATTTTTGTG
TTTCTGCAGAGTTTTGCACAAAATCTGTTCCCATGCAAACCAATGAGGGAGAAGTATCGGAAGAAAGCAGTTCCAAGGTGGAACAGGAGG
ATTTTGTAATGGAAGGGCATGGCAAGACTCCACCTCCTGGTGAAGAAAGCAAACAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCT
GTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTG
GCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTA
AGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGC
ACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGC
CATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCAT
CTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGA
ATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAG
AGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCAT
ATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAA
AATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTT
TCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCT
CTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTC
CTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTT

>92858_92858_5_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000301923_ADSL_chr22_40754868_ENST00000342312_length(amino acids)=326AA_BP=1
MCCPRYCQRQYFCVSAEFCTKSVPMQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQPAQLTTVGKRCCLWIQDLCMDLQNLKRV
RDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEME
EPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVI

--------------------------------------------------------------
>92858_92858_6_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000301923_ADSL_chr22_40754868_ENST00000454266_length(transcript)=1480nt_BP=415nt
TTGTTTATTTTGTTTTTAGTTTTTGGGGTCCCCGTGCTGCTGCAAGGCGAAACGGGAGGGAGTGACCCCTGCGCCCCTCAGTCCCCCCTA
CGACGTCGCCTCCATAGTCTGCGGAGAAGCGGAGACTGCGCGCCTCGCCTCACAGCGAAACGCCGCGCACTCGGAGCCGGCACGGCTCGG
CGGGTTGTGGTTTTTTGCACTGAATGTAACCTAGACTCATCTTCACGGGCTTGTGTTGCCCCAGGTACTGTCAAAGGCAGTATTTTTGTG
TTTCTGCAGAGTTTTGCACAAAATCTGTTCCCATGCAAACCAATGAGGGAGAAGTATCGGAAGAAAGCAGTTCCAAGGTGGAACAGGAGG
ATTTTGTAATGGAAGGGCATGGCAAGACTCCACCTCCTGGTGAAGAAAGCAAACAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCT
GTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTG
GCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTA
AGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGC
ACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGC
CATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCAT
CTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGA
ATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAG
AGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTG
TGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATT
TACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATG
AAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAAT

>92858_92858_6_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000301923_ADSL_chr22_40754868_ENST00000454266_length(amino acids)=385AA_BP=1
MCCPRYCQRQYFCVSAEFCTKSVPMQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQPAQLTTVGKRCCLWIQDLCMDLQNLKRV
RDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEME
EPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVI
ERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQR

--------------------------------------------------------------
>92858_92858_7_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000402203_ADSL_chr22_40754867_ENST00000216194_length(transcript)=1803nt_BP=348nt
CGGCCCGCGGAGGCGCGTCCGCCCCTGGCTGGCGGTGGCAGAGGGAGGCGTCAGGCCTCGGATCCTCGGGTCCCTGCGCAGCGTCCCGGC
CTGTGTGCAGGACCTGCGTGACAAGGGTTGTGGTTTTTTGCACTGAATGTAACCTAGACTCATCTTCACGGGCTTGTGTTGCCCCAGGTA
CTGTCAAAGGCAGTATTTTTGTGTTTCTGCAGAGTTTTGCACAAAATCTGTTCCCATGCAAACCAATGAGGGAGAAGTATCGGAAGAAAG
CAGTTCCAAGGTGGAACAGGAGGATTTTGTAATGGAAGGGCATGGCAAGACTCCACCTCCTGGTGAAGAAAGCAAACAGCCTGCACAGCT
GACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTT
CCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGAT
GGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCT
GGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACA
GCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGT
CATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATT
TCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCA
AGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGT
GCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCC
CATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGT
GTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATT
GTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCT
TCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAA
ATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAA
GTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTC
AGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGTGATGAAGTTTGGAACTACAGTAAATACTTAAAAAAAAAAAAAAAAAGAACC

>92858_92858_7_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000402203_ADSL_chr22_40754867_ENST00000216194_length(amino acids)=385AA_BP=1
MCCPRYCQRQYFCVSAEFCTKSVPMQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQPAQLTTVGKRCCLWIQDLCMDLQNLKRV
RDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEME
EPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVI
ERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQR

--------------------------------------------------------------
>92858_92858_8_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000402203_ADSL_chr22_40754867_ENST00000342312_length(transcript)=1618nt_BP=348nt
CGGCCCGCGGAGGCGCGTCCGCCCCTGGCTGGCGGTGGCAGAGGGAGGCGTCAGGCCTCGGATCCTCGGGTCCCTGCGCAGCGTCCCGGC
CTGTGTGCAGGACCTGCGTGACAAGGGTTGTGGTTTTTTGCACTGAATGTAACCTAGACTCATCTTCACGGGCTTGTGTTGCCCCAGGTA
CTGTCAAAGGCAGTATTTTTGTGTTTCTGCAGAGTTTTGCACAAAATCTGTTCCCATGCAAACCAATGAGGGAGAAGTATCGGAAGAAAG
CAGTTCCAAGGTGGAACAGGAGGATTTTGTAATGGAAGGGCATGGCAAGACTCCACCTCCTGGTGAAGAAAGCAAACAGCCTGCACAGCT
GACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTT
CCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGAT
GGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCT
GGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACA
GCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGT
CATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATT
TCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCA
AGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGA
GGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATC
ATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCT
TCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAG
TAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGT
AAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATG

>92858_92858_8_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000402203_ADSL_chr22_40754867_ENST00000342312_length(amino acids)=326AA_BP=1
MCCPRYCQRQYFCVSAEFCTKSVPMQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQPAQLTTVGKRCCLWIQDLCMDLQNLKRV
RDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEME
EPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVI

--------------------------------------------------------------
>92858_92858_9_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000402203_ADSL_chr22_40754867_ENST00000454266_length(transcript)=1413nt_BP=348nt
CGGCCCGCGGAGGCGCGTCCGCCCCTGGCTGGCGGTGGCAGAGGGAGGCGTCAGGCCTCGGATCCTCGGGTCCCTGCGCAGCGTCCCGGC
CTGTGTGCAGGACCTGCGTGACAAGGGTTGTGGTTTTTTGCACTGAATGTAACCTAGACTCATCTTCACGGGCTTGTGTTGCCCCAGGTA
CTGTCAAAGGCAGTATTTTTGTGTTTCTGCAGAGTTTTGCACAAAATCTGTTCCCATGCAAACCAATGAGGGAGAAGTATCGGAAGAAAG
CAGTTCCAAGGTGGAACAGGAGGATTTTGTAATGGAAGGGCATGGCAAGACTCCACCTCCTGGTGAAGAAAGCAAACAGCCTGCACAGCT
GACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTT
CCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGAT
GGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCT
GGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACA
GCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGT
CATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATT
TCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCA
AGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGT
GCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCC
CATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGT
GTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATT

>92858_92858_9_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000402203_ADSL_chr22_40754867_ENST00000454266_length(amino acids)=385AA_BP=1
MCCPRYCQRQYFCVSAEFCTKSVPMQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQPAQLTTVGKRCCLWIQDLCMDLQNLKRV
RDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEME
EPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVI
ERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQR

--------------------------------------------------------------
>92858_92858_10_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000402203_ADSL_chr22_40754868_ENST00000216194_length(transcript)=1803nt_BP=348nt
CGGCCCGCGGAGGCGCGTCCGCCCCTGGCTGGCGGTGGCAGAGGGAGGCGTCAGGCCTCGGATCCTCGGGTCCCTGCGCAGCGTCCCGGC
CTGTGTGCAGGACCTGCGTGACAAGGGTTGTGGTTTTTTGCACTGAATGTAACCTAGACTCATCTTCACGGGCTTGTGTTGCCCCAGGTA
CTGTCAAAGGCAGTATTTTTGTGTTTCTGCAGAGTTTTGCACAAAATCTGTTCCCATGCAAACCAATGAGGGAGAAGTATCGGAAGAAAG
CAGTTCCAAGGTGGAACAGGAGGATTTTGTAATGGAAGGGCATGGCAAGACTCCACCTCCTGGTGAAGAAAGCAAACAGCCTGCACAGCT
GACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTT
CCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGAT
GGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCT
GGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACA
GCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGT
CATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATT
TCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCA
AGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGT
GCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCC
CATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGT
GTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATT
GTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCT
TCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAA
ATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAA
GTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTC
AGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGTGATGAAGTTTGGAACTACAGTAAATACTTAAAAAAAAAAAAAAAAAGAACC

>92858_92858_10_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000402203_ADSL_chr22_40754868_ENST00000216194_length(amino acids)=385AA_BP=1
MCCPRYCQRQYFCVSAEFCTKSVPMQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQPAQLTTVGKRCCLWIQDLCMDLQNLKRV
RDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEME
EPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVI
ERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQR

--------------------------------------------------------------
>92858_92858_11_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000402203_ADSL_chr22_40754868_ENST00000342312_length(transcript)=1618nt_BP=348nt
CGGCCCGCGGAGGCGCGTCCGCCCCTGGCTGGCGGTGGCAGAGGGAGGCGTCAGGCCTCGGATCCTCGGGTCCCTGCGCAGCGTCCCGGC
CTGTGTGCAGGACCTGCGTGACAAGGGTTGTGGTTTTTTGCACTGAATGTAACCTAGACTCATCTTCACGGGCTTGTGTTGCCCCAGGTA
CTGTCAAAGGCAGTATTTTTGTGTTTCTGCAGAGTTTTGCACAAAATCTGTTCCCATGCAAACCAATGAGGGAGAAGTATCGGAAGAAAG
CAGTTCCAAGGTGGAACAGGAGGATTTTGTAATGGAAGGGCATGGCAAGACTCCACCTCCTGGTGAAGAAAGCAAACAGCCTGCACAGCT
GACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTT
CCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGAT
GGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCT
GGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACA
GCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGT
CATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATT
TCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCA
AGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGA
GGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATC
ATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCT
TCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAG
TAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGT
AAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATG

>92858_92858_11_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000402203_ADSL_chr22_40754868_ENST00000342312_length(amino acids)=326AA_BP=1
MCCPRYCQRQYFCVSAEFCTKSVPMQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQPAQLTTVGKRCCLWIQDLCMDLQNLKRV
RDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEME
EPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVI

--------------------------------------------------------------
>92858_92858_12_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000402203_ADSL_chr22_40754868_ENST00000454266_length(transcript)=1413nt_BP=348nt
CGGCCCGCGGAGGCGCGTCCGCCCCTGGCTGGCGGTGGCAGAGGGAGGCGTCAGGCCTCGGATCCTCGGGTCCCTGCGCAGCGTCCCGGC
CTGTGTGCAGGACCTGCGTGACAAGGGTTGTGGTTTTTTGCACTGAATGTAACCTAGACTCATCTTCACGGGCTTGTGTTGCCCCAGGTA
CTGTCAAAGGCAGTATTTTTGTGTTTCTGCAGAGTTTTGCACAAAATCTGTTCCCATGCAAACCAATGAGGGAGAAGTATCGGAAGAAAG
CAGTTCCAAGGTGGAACAGGAGGATTTTGTAATGGAAGGGCATGGCAAGACTCCACCTCCTGGTGAAGAAAGCAAACAGCCTGCACAGCT
GACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTT
CCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGAT
GGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCT
GGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACA
GCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGT
CATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATT
TCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCA
AGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGT
GCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCC
CATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGT
GTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATT

>92858_92858_12_TNRC6B-ADSL_TNRC6B_chr22_40552186_ENST00000402203_ADSL_chr22_40754868_ENST00000454266_length(amino acids)=385AA_BP=1
MCCPRYCQRQYFCVSAEFCTKSVPMQTNEGEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQPAQLTTVGKRCCLWIQDLCMDLQNLKRV
RDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEME
EPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVI
ERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQR

--------------------------------------------------------------
>92858_92858_13_TNRC6B-ADSL_TNRC6B_chr22_40574144_ENST00000335727_ADSL_chr22_40754868_ENST00000216194_length(transcript)=1654nt_BP=199nt
GAGAGAGCAAGAGGGAGAGTGTGTGAGAGAGAGTTAGTTCAAGCCAAAATGGCCGACAGAGTCTCTGCTGGTTTCTGAATATTTAAAATA
CAAAAAAACAGATAGACAAAAAGAATTCATTTTTTGGACCTTTTTTCATTTCCATTTCTACCTTGTATGCCTCAATTTGCTGGATTTAAG
CACTGCTGCACTTTATGAGGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGA
ACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAG
ATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACAC
GAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACC
TCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCT
GCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTG
CCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGT
ACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTA
GCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAG
AGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCC
AGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGT
AGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATT
GTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAG
CGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTT
AGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAA
TAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGTGATGAAGTTTGGAACTACAG

>92858_92858_13_TNRC6B-ADSL_TNRC6B_chr22_40574144_ENST00000335727_ADSL_chr22_40754868_ENST00000216194_length(amino acids)=329AA_BP=5
MLHFMRPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTR
KVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSA
NRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIE

--------------------------------------------------------------
>92858_92858_14_TNRC6B-ADSL_TNRC6B_chr22_40574144_ENST00000335727_ADSL_chr22_40754868_ENST00000342312_length(transcript)=1469nt_BP=199nt
GAGAGAGCAAGAGGGAGAGTGTGTGAGAGAGAGTTAGTTCAAGCCAAAATGGCCGACAGAGTCTCTGCTGGTTTCTGAATATTTAAAATA
CAAAAAAACAGATAGACAAAAAGAATTCATTTTTTGGACCTTTTTTCATTTCCATTTCTACCTTGTATGCCTCAATTTGCTGGATTTAAG
CACTGCTGCACTTTATGAGGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGA
ACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAG
ATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACAC
GAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACC
TCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCT
GCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTG
CCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGT
ACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTA
GCCGCCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTC
TGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGA
ATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAA
GAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAG
TTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCA
AAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGTGATGAAGTTTGGAACTA

>92858_92858_14_TNRC6B-ADSL_TNRC6B_chr22_40574144_ENST00000335727_ADSL_chr22_40754868_ENST00000342312_length(amino acids)=270AA_BP=5
MLHFMRPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTR
KVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSA
NRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVKAELCL

--------------------------------------------------------------
>92858_92858_15_TNRC6B-ADSL_TNRC6B_chr22_40574144_ENST00000335727_ADSL_chr22_40754868_ENST00000454266_length(transcript)=1264nt_BP=199nt
GAGAGAGCAAGAGGGAGAGTGTGTGAGAGAGAGTTAGTTCAAGCCAAAATGGCCGACAGAGTCTCTGCTGGTTTCTGAATATTTAAAATA
CAAAAAAACAGATAGACAAAAAGAATTCATTTTTTGGACCTTTTTTCATTTCCATTTCTACCTTGTATGCCTCAATTTGCTGGATTTAAG
CACTGCTGCACTTTATGAGGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGA
ACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAG
ATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACAC
GAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACC
TCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCT
GCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTG
CCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGT
ACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTA
GCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAG
AGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCC
AGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGT
AGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATT

>92858_92858_15_TNRC6B-ADSL_TNRC6B_chr22_40574144_ENST00000335727_ADSL_chr22_40754868_ENST00000454266_length(amino acids)=329AA_BP=5
MLHFMRPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTR
KVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSA
NRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIE

--------------------------------------------------------------
>92858_92858_16_TNRC6B-ADSL_TNRC6B_chr22_40574144_ENST00000454349_ADSL_chr22_40754868_ENST00000216194_length(transcript)=1671nt_BP=216nt
AGAGACAGAGAGGGAGAGAGAGAGCAAGAGGGAGAGTGTGTGAGAGAGAGTTAGTTCAAGCCAAAATGGCCGACAGAGTCTCTGCTGGTT
TCTGAATATTTAAAATACAAAAAAACAGATAGACAAAAAGAATTCATTTTTTGGACCTTTTTTCATTTCCATTTCTACCTTGTATGCCTC
AATTTGCTGGATTTAAGCACTGCTGCACTTTATGAGGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCT
TTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCT
GCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCAC
AGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACAT
ACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCAT
GCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACG
CACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTC
TGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCAT
GGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGG
TGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTT
CACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAA
AGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTT
ATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAAC
AAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTT
CCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTG
ATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGTGAT

>92858_92858_16_TNRC6B-ADSL_TNRC6B_chr22_40574144_ENST00000454349_ADSL_chr22_40754868_ENST00000216194_length(amino acids)=329AA_BP=5
MLHFMRPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTR
KVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSA
NRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIE

--------------------------------------------------------------
>92858_92858_17_TNRC6B-ADSL_TNRC6B_chr22_40574144_ENST00000454349_ADSL_chr22_40754868_ENST00000342312_length(transcript)=1486nt_BP=216nt
AGAGACAGAGAGGGAGAGAGAGAGCAAGAGGGAGAGTGTGTGAGAGAGAGTTAGTTCAAGCCAAAATGGCCGACAGAGTCTCTGCTGGTT
TCTGAATATTTAAAATACAAAAAAACAGATAGACAAAAAGAATTCATTTTTTGGACCTTTTTTCATTTCCATTTCTACCTTGTATGCCTC
AATTTGCTGGATTTAAGCACTGCTGCACTTTATGAGGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCT
TTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCT
GCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCAC
AGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACAT
ACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCAT
GCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACG
CACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTC
TGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCAT
GGTCAAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGT
GAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGC
CTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTC
AACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATAT
TTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAAT
TTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGT

>92858_92858_17_TNRC6B-ADSL_TNRC6B_chr22_40574144_ENST00000454349_ADSL_chr22_40754868_ENST00000342312_length(amino acids)=270AA_BP=5
MLHFMRPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTR
KVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSA
NRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVKAELCL

--------------------------------------------------------------
>92858_92858_18_TNRC6B-ADSL_TNRC6B_chr22_40574144_ENST00000454349_ADSL_chr22_40754868_ENST00000454266_length(transcript)=1281nt_BP=216nt
AGAGACAGAGAGGGAGAGAGAGAGCAAGAGGGAGAGTGTGTGAGAGAGAGTTAGTTCAAGCCAAAATGGCCGACAGAGTCTCTGCTGGTT
TCTGAATATTTAAAATACAAAAAAACAGATAGACAAAAAGAATTCATTTTTTGGACCTTTTTTCATTTCCATTTCTACCTTGTATGCCTC
AATTTGCTGGATTTAAGCACTGCTGCACTTTATGAGGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCT
TTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCT
GCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCAC
AGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACAT
ACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCAT
GCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACG
CACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTC
TGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCAT
GGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGG
TGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTT
CACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAA
AGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTT

>92858_92858_18_TNRC6B-ADSL_TNRC6B_chr22_40574144_ENST00000454349_ADSL_chr22_40754868_ENST00000454266_length(amino acids)=329AA_BP=5
MLHFMRPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTR
KVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSA
NRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TNRC6B-ADSL


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000301923+4241_99437.6666666666666641030.0argonaute proteins
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000335727+1211_99401724.0argonaute proteins
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000402203+4241_99437.6666666666666641030.0argonaute proteins
HgeneTNRC6Bchr22:40552186chr22:40754867ENST00000454349+1231_99401834.0argonaute proteins
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000301923+4241_99437.6666666666666641030.0argonaute proteins
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000335727+1211_99401724.0argonaute proteins
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000402203+4241_99437.6666666666666641030.0argonaute proteins
HgeneTNRC6Bchr22:40552186chr22:40754868ENST00000454349+1231_99401834.0argonaute proteins
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000301923+1241_99401030.0argonaute proteins
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000335727+1211_9941.66666666666666671724.0argonaute proteins
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000402203+1241_99401030.0argonaute proteins
HgeneTNRC6Bchr22:40574144chr22:40754868ENST00000454349+1231_9941.66666666666666671834.0argonaute proteins


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TNRC6B-ADSL


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TNRC6B-ADSL


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource