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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TNXB-ZNF263 (FusionGDB2 ID:92963)

Fusion Gene Summary for TNXB-ZNF263

check button Fusion gene summary
Fusion gene informationFusion gene name: TNXB-ZNF263
Fusion gene ID: 92963
HgeneTgene
Gene symbol

TNXB

ZNF263

Gene ID

7148

10127

Gene nametenascin XBzinc finger protein 263
SynonymsEDS3|EDSCLL|EDSCLL1|HXBL|TENX|TN-X|TNX|TNXB1|TNXB2|TNXBS|VUR8|XB|XBSFPM315|ZKSCAN12|ZSCAN44
Cytomap

6p21.33-p21.32

16p13.3

Type of geneprotein-codingprotein-coding
Descriptiontenascin-Xgrowth-inhibiting protein 45hexabrachion-like proteintenascin XB1tenascin XB2zinc finger protein 263zinc finger protein FPM315zinc finger protein with KRAB and SCAN domains 12
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000375244, ENST00000375247, 
ENST00000383159, ENST00000424718, 
ENST00000433037, ENST00000440248, 
ENST00000451343, ENST00000464376, 
ENST00000465958, ENST00000469250, 
ENST00000471059, ENST00000475986, 
ENST00000479795, ENST00000489006, 
ENST00000546684, ENST00000548628, 
ENST00000548649, ENST00000549232, 
ENST00000549652, ENST00000550212, 
ENST00000550539, ENST00000551201, 
ENST00000551808, ENST00000552149, 
ENST00000552665, ENST00000553092, 
ENST00000219069, ENST00000573578, 
ENST00000574253, ENST00000538765, 
ENST00000573951, 
Fusion gene scores* DoF score4 X 4 X 4=644 X 5 X 1=20
# samples 45
** MAII scorelog2(4/64*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/20*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: TNXB [Title/Abstract] AND ZNF263 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTNXB(32025861)-ZNF263(3333626), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneZNF263

GO:0000122

negative regulation of transcription by RNA polymerase II

19887448


check buttonFusion gene breakpoints across TNXB (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across ZNF263 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ADN995841TNXBchr6

32025861

-ZNF263chr16

3333626

+


Top

Fusion Gene ORF analysis for TNXB-ZNF263

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-5UTRENST00000375244ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000375244ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000375244ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000375247ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000375247ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000375247ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000383159ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000383159ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000383159ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000424718ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000424718ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000424718ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000433037ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000433037ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000433037ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000440248ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000440248ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000440248ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000451343ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000451343ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000451343ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000464376ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000464376ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000464376ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000465958ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000465958ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000465958ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000469250ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000469250ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000469250ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000471059ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000471059ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000471059ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000475986ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000475986ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000475986ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000479795ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000479795ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000479795ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000489006ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000489006ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000489006ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000546684ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000546684ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000546684ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000548628ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000548628ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000548628ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000548649ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000548649ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000548649ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000549232ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000549232ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000549232ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000549652ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000549652ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000549652ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000550212ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000550212ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000550212ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000550539ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000550539ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000550539ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000551201ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000551201ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000551201ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000551808ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000551808ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000551808ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000552149ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000552149ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000552149ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000552665ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000552665ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000552665ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000553092ENST00000219069TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000553092ENST00000573578TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-5UTRENST00000553092ENST00000574253TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000375244ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000375244ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000375247ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000375247ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000383159ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000383159ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000424718ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000424718ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000433037ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000433037ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000440248ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000440248ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000451343ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000451343ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000464376ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000464376ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000465958ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000465958ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000469250ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000469250ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000471059ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000471059ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000475986ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000475986ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000479795ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000479795ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000489006ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000489006ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000546684ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000546684ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000548628ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000548628ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000548649ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000548649ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000549232ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000549232ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000549652ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000549652ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000550212ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000550212ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000550539ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000550539ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000551201ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000551201ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000551808ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000551808ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000552149ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000552149ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000552665ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000552665ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000553092ENST00000538765TNXBchr6

32025861

-ZNF263chr16

3333626

+
intron-intronENST00000553092ENST00000573951TNXBchr6

32025861

-ZNF263chr16

3333626

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

Top

Fusion Genomic Features for TNXB-ZNF263


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for TNXB-ZNF263


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:32025861/:3333626)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for TNXB-ZNF263


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for TNXB-ZNF263


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TNXB-ZNF263


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TNXB-ZNF263


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource