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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:TPM3-TPM3 (FusionGDB2 ID:93393)

Fusion Gene Summary for TPM3-TPM3

Fusion gene summary

Fusion gene information	Fusion gene name: TPM3-TPM3
	Fusion gene ID: 93393
		Hgene	Tgene
	Gene symbol	TPM3	TPM3
	Gene ID	7170	7170
	Gene name	tropomyosin 3	tropomyosin 3
	Synonyms	CAPM1\|CFTD\|HEL-189\|HEL-S-82p\|NEM1\|OK/SW-cl.5\|TM-5\|TM3\|TM30\|TM30nm\|TM5\|TPM3nu\|TPMsk3\|TRK\|hscp30	CAPM1\|CFTD\|HEL-189\|HEL-S-82p\|NEM1\|OK/SW-cl.5\|TM-5\|TM3\|TM30\|TM30nm\|TM5\|TPM3nu\|TPMsk3\|TRK\|hscp30
	Cytomap	1q21.3	1q21.3
	Type of gene	protein-coding	protein-coding
	Description	tropomyosin alpha-3 chainalpha-tropomyosin, slow skeletalcytoskeletal tropomyosin TM30epididymis luminal protein 189epididymis secretory sperm binding protein Li 82pheat-stable cytoskeletal protein 30 kDatropomyosin 3 nutropomyosin gammatropomyosi	tropomyosin alpha-3 chainalpha-tropomyosin, slow skeletalcytoskeletal tropomyosin TM30epididymis luminal protein 189epididymis secretory sperm binding protein Li 82pheat-stable cytoskeletal protein 30 kDatropomyosin 3 nutropomyosin gammatropomyosi
	Modification date	20200328	20200328
	UniProtAcc	.	P06753
	Ensembl transtripts involved in fusion gene	ENST00000271850, ENST00000302206, ENST00000323144, ENST00000328159, ENST00000330188, ENST00000341372, ENST00000341485, ENST00000368530, ENST00000368531, ENST00000368533, ENST00000469717,	ENST00000328159, ENST00000330188, ENST00000341372, ENST00000341485, ENST00000368533, ENST00000469717, ENST00000271850, ENST00000302206, ENST00000323144, ENST00000368530, ENST00000368531,
Fusion gene scores	* DoF score	15 X 22 X 8=2640	9 X 10 X 5=450
	# samples	24	12
	** MAII score	log2(24/2640*10)=-3.4594316186373 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(12/450*10)=-1.90689059560852 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: TPM3 [Title/Abstract] AND TPM3 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	TPM3(154128113)-TPM3(154128094), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across TPM3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across TPM3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS5.0	N/A	AA075545	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
ChiTaRS5.0	N/A	AW602539	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
ChiTaRS5.0	N/A	DL051249	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
ChiTaRS5.0	N/A	EC445019	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+

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Fusion Gene ORF analysis for TPM3-TPM3

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-3UTR	ENST00000271850	ENST00000328159	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
5CDS-3UTR	ENST00000271850	ENST00000330188	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
5CDS-3UTR	ENST00000271850	ENST00000341372	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
5CDS-3UTR	ENST00000271850	ENST00000341485	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
5CDS-3UTR	ENST00000271850	ENST00000368533	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
5CDS-5UTR	ENST00000271850	ENST00000469717	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
5CDS-intron	ENST00000271850	ENST00000271850	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
5CDS-intron	ENST00000271850	ENST00000302206	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
5CDS-intron	ENST00000271850	ENST00000323144	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
5CDS-intron	ENST00000271850	ENST00000368530	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
5CDS-intron	ENST00000271850	ENST00000368531	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000271850	ENST00000328159	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000271850	ENST00000330188	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000271850	ENST00000341372	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000271850	ENST00000341485	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000271850	ENST00000368533	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-3UTR	ENST00000271850	ENST00000368533	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000302206	ENST00000328159	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000302206	ENST00000328159	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000302206	ENST00000330188	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000302206	ENST00000330188	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000302206	ENST00000341372	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000302206	ENST00000341372	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000302206	ENST00000341485	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000302206	ENST00000341485	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000302206	ENST00000368533	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-3UTR	ENST00000302206	ENST00000368533	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000302206	ENST00000368533	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000323144	ENST00000328159	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000323144	ENST00000328159	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000323144	ENST00000330188	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000323144	ENST00000330188	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000323144	ENST00000341372	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000323144	ENST00000341372	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000323144	ENST00000341485	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000323144	ENST00000341485	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000323144	ENST00000368533	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-3UTR	ENST00000323144	ENST00000368533	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000323144	ENST00000368533	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000328159	ENST00000328159	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000328159	ENST00000328159	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000328159	ENST00000330188	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000328159	ENST00000330188	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000328159	ENST00000341372	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000328159	ENST00000341372	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000328159	ENST00000341485	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000328159	ENST00000341485	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000328159	ENST00000368533	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-3UTR	ENST00000328159	ENST00000368533	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000328159	ENST00000368533	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000330188	ENST00000328159	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000330188	ENST00000328159	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000330188	ENST00000330188	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000330188	ENST00000330188	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000330188	ENST00000341372	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000330188	ENST00000341372	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000330188	ENST00000341485	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000330188	ENST00000341485	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000330188	ENST00000368533	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-3UTR	ENST00000330188	ENST00000368533	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000330188	ENST00000368533	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000341372	ENST00000328159	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000341372	ENST00000328159	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000341372	ENST00000330188	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000341372	ENST00000330188	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000341372	ENST00000341372	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000341372	ENST00000341372	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000341372	ENST00000341485	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000341372	ENST00000341485	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000341372	ENST00000368533	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-3UTR	ENST00000341372	ENST00000368533	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000341372	ENST00000368533	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000341485	ENST00000328159	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000341485	ENST00000328159	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000341485	ENST00000330188	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000341485	ENST00000330188	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000341485	ENST00000341372	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000341485	ENST00000341372	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000341485	ENST00000341485	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000341485	ENST00000341485	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000341485	ENST00000368533	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-3UTR	ENST00000341485	ENST00000368533	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000341485	ENST00000368533	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000368530	ENST00000328159	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000368530	ENST00000328159	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000368530	ENST00000330188	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000368530	ENST00000330188	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000368530	ENST00000341372	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000368530	ENST00000341372	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000368530	ENST00000341485	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000368530	ENST00000341485	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000368530	ENST00000368533	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-3UTR	ENST00000368530	ENST00000368533	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000368530	ENST00000368533	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000368531	ENST00000328159	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000368531	ENST00000328159	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000368531	ENST00000330188	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000368531	ENST00000330188	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000368531	ENST00000341372	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000368531	ENST00000341372	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000368531	ENST00000341485	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000368531	ENST00000341485	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000368531	ENST00000368533	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-3UTR	ENST00000368531	ENST00000368533	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000368531	ENST00000368533	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000368533	ENST00000328159	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000368533	ENST00000328159	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000368533	ENST00000330188	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000368533	ENST00000330188	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000368533	ENST00000341372	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000368533	ENST00000341372	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000368533	ENST00000341485	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000368533	ENST00000341485	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000368533	ENST00000368533	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-3UTR	ENST00000368533	ENST00000368533	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000368533	ENST00000368533	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000469717	ENST00000328159	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000469717	ENST00000328159	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000469717	ENST00000330188	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000469717	ENST00000330188	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000469717	ENST00000341372	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000469717	ENST00000341372	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000469717	ENST00000341485	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000469717	ENST00000341485	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-3UTR	ENST00000469717	ENST00000368533	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-3UTR	ENST00000469717	ENST00000368533	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-3UTR	ENST00000469717	ENST00000368533	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-5UTR	ENST00000271850	ENST00000469717	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-5UTR	ENST00000302206	ENST00000469717	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-5UTR	ENST00000302206	ENST00000469717	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-5UTR	ENST00000323144	ENST00000469717	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-5UTR	ENST00000323144	ENST00000469717	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-5UTR	ENST00000328159	ENST00000469717	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-5UTR	ENST00000328159	ENST00000469717	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-5UTR	ENST00000330188	ENST00000469717	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-5UTR	ENST00000330188	ENST00000469717	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-5UTR	ENST00000341372	ENST00000469717	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-5UTR	ENST00000341372	ENST00000469717	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-5UTR	ENST00000341485	ENST00000469717	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-5UTR	ENST00000341485	ENST00000469717	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-5UTR	ENST00000368530	ENST00000469717	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-5UTR	ENST00000368530	ENST00000469717	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-5UTR	ENST00000368531	ENST00000469717	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-5UTR	ENST00000368531	ENST00000469717	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-5UTR	ENST00000368533	ENST00000469717	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-5UTR	ENST00000368533	ENST00000469717	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-5UTR	ENST00000469717	ENST00000469717	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-5UTR	ENST00000469717	ENST00000469717	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000271850	ENST00000271850	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000271850	ENST00000271850	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000271850	ENST00000302206	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000271850	ENST00000302206	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000271850	ENST00000323144	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000271850	ENST00000323144	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000271850	ENST00000328159	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000271850	ENST00000330188	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000271850	ENST00000341372	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000271850	ENST00000341485	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000271850	ENST00000368530	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000271850	ENST00000368530	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000271850	ENST00000368531	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000271850	ENST00000368531	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000271850	ENST00000469717	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000302206	ENST00000271850	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000302206	ENST00000271850	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000302206	ENST00000271850	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000302206	ENST00000302206	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000302206	ENST00000302206	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000302206	ENST00000302206	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000302206	ENST00000323144	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000302206	ENST00000323144	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000302206	ENST00000323144	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000302206	ENST00000328159	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000302206	ENST00000330188	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000302206	ENST00000341372	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000302206	ENST00000341485	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000302206	ENST00000368530	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000302206	ENST00000368530	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000302206	ENST00000368530	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000302206	ENST00000368531	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000302206	ENST00000368531	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000302206	ENST00000368531	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000302206	ENST00000469717	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000323144	ENST00000271850	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000323144	ENST00000271850	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000323144	ENST00000271850	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000323144	ENST00000302206	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000323144	ENST00000302206	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000323144	ENST00000302206	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000323144	ENST00000323144	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000323144	ENST00000323144	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000323144	ENST00000323144	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000323144	ENST00000328159	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000323144	ENST00000330188	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000323144	ENST00000341372	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000323144	ENST00000341485	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000323144	ENST00000368530	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000323144	ENST00000368530	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000323144	ENST00000368530	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000323144	ENST00000368531	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000323144	ENST00000368531	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000323144	ENST00000368531	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000323144	ENST00000469717	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000328159	ENST00000271850	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000328159	ENST00000271850	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000328159	ENST00000271850	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000328159	ENST00000302206	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000328159	ENST00000302206	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000328159	ENST00000302206	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000328159	ENST00000323144	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000328159	ENST00000323144	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000328159	ENST00000323144	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000328159	ENST00000328159	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000328159	ENST00000330188	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000328159	ENST00000341372	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000328159	ENST00000341485	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000328159	ENST00000368530	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000328159	ENST00000368530	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000328159	ENST00000368530	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000328159	ENST00000368531	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000328159	ENST00000368531	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000328159	ENST00000368531	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000328159	ENST00000469717	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000330188	ENST00000271850	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000330188	ENST00000271850	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000330188	ENST00000271850	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000330188	ENST00000302206	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000330188	ENST00000302206	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000330188	ENST00000302206	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000330188	ENST00000323144	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000330188	ENST00000323144	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000330188	ENST00000323144	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000330188	ENST00000328159	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000330188	ENST00000330188	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000330188	ENST00000341372	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000330188	ENST00000341485	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000330188	ENST00000368530	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000330188	ENST00000368530	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000330188	ENST00000368530	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000330188	ENST00000368531	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000330188	ENST00000368531	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000330188	ENST00000368531	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000330188	ENST00000469717	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341372	ENST00000271850	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341372	ENST00000271850	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000341372	ENST00000271850	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000341372	ENST00000302206	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341372	ENST00000302206	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000341372	ENST00000302206	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000341372	ENST00000323144	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341372	ENST00000323144	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000341372	ENST00000323144	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000341372	ENST00000328159	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341372	ENST00000330188	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341372	ENST00000341372	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341372	ENST00000341485	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341372	ENST00000368530	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341372	ENST00000368530	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000341372	ENST00000368530	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000341372	ENST00000368531	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341372	ENST00000368531	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000341372	ENST00000368531	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000341372	ENST00000469717	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341485	ENST00000271850	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341485	ENST00000271850	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000341485	ENST00000271850	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000341485	ENST00000302206	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341485	ENST00000302206	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000341485	ENST00000302206	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000341485	ENST00000323144	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341485	ENST00000323144	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000341485	ENST00000323144	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000341485	ENST00000328159	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341485	ENST00000330188	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341485	ENST00000341372	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341485	ENST00000341485	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341485	ENST00000368530	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341485	ENST00000368530	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000341485	ENST00000368530	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000341485	ENST00000368531	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000341485	ENST00000368531	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000341485	ENST00000368531	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000341485	ENST00000469717	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368530	ENST00000271850	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368530	ENST00000271850	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000368530	ENST00000271850	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000368530	ENST00000302206	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368530	ENST00000302206	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000368530	ENST00000302206	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000368530	ENST00000323144	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368530	ENST00000323144	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000368530	ENST00000323144	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000368530	ENST00000328159	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368530	ENST00000330188	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368530	ENST00000341372	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368530	ENST00000341485	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368530	ENST00000368530	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368530	ENST00000368530	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000368530	ENST00000368530	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000368530	ENST00000368531	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368530	ENST00000368531	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000368530	ENST00000368531	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000368530	ENST00000469717	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368531	ENST00000271850	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368531	ENST00000271850	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000368531	ENST00000271850	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000368531	ENST00000302206	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368531	ENST00000302206	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000368531	ENST00000302206	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000368531	ENST00000323144	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368531	ENST00000323144	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000368531	ENST00000323144	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000368531	ENST00000328159	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368531	ENST00000330188	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368531	ENST00000341372	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368531	ENST00000341485	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368531	ENST00000368530	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368531	ENST00000368530	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000368531	ENST00000368530	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000368531	ENST00000368531	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368531	ENST00000368531	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000368531	ENST00000368531	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000368531	ENST00000469717	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368533	ENST00000271850	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368533	ENST00000271850	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000368533	ENST00000271850	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000368533	ENST00000302206	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368533	ENST00000302206	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000368533	ENST00000302206	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000368533	ENST00000323144	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368533	ENST00000323144	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000368533	ENST00000323144	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000368533	ENST00000328159	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368533	ENST00000330188	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368533	ENST00000341372	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368533	ENST00000341485	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368533	ENST00000368530	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368533	ENST00000368530	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000368533	ENST00000368530	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000368533	ENST00000368531	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000368533	ENST00000368531	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000368533	ENST00000368531	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000368533	ENST00000469717	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000469717	ENST00000271850	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000469717	ENST00000271850	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000469717	ENST00000271850	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000469717	ENST00000302206	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000469717	ENST00000302206	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000469717	ENST00000302206	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000469717	ENST00000323144	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000469717	ENST00000323144	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000469717	ENST00000323144	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000469717	ENST00000328159	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000469717	ENST00000330188	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000469717	ENST00000341372	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000469717	ENST00000341485	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000469717	ENST00000368530	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000469717	ENST00000368530	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000469717	ENST00000368530	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000469717	ENST00000368531	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-
intron-intron	ENST00000469717	ENST00000368531	TPM3	chr1	154129797	+	TPM3	chr1	154129782	-
intron-intron	ENST00000469717	ENST00000368531	TPM3	chr1	154129576	-	TPM3	chr1	154129614	+
intron-intron	ENST00000469717	ENST00000469717	TPM3	chr1	154128113	+	TPM3	chr1	154128094	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

No-coding score

Coding score

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Fusion Genomic Features for TPM3-TPM3

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TPM3-TPM3

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:154128113/:154128094)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	TPM3 P06753
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. {ECO:0000250\|UniProtKB:P09493}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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Fusion Gene Sequence for TPM3-TPM3

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for TPM3-TPM3

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for TPM3-TPM3

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for TPM3-TPM3

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source