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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BCL2L13-DGCR14 (FusionGDB2 ID:9353)

Fusion Gene Summary for BCL2L13-DGCR14

check button Fusion gene summary
Fusion gene informationFusion gene name: BCL2L13-DGCR14
Fusion gene ID: 9353
HgeneTgene
Gene symbol

BCL2L13

DGCR14

Gene ID

23786

8220

Gene nameBCL2 like 13ess-2 splicing factor homolog
SynonymsBCL-RAMBO|Bcl2-L-13|MIL1DGCR13|DGCR14|DGS-H|DGS-I|DGSH|DGSI|ES2|ESS-2|Es2el|bis1
Cytomap

22q11.21

22q11.21|22q11.2

Type of geneprotein-codingprotein-coding
Descriptionbcl-2-like protein 13BCL2-like 13 (apoptosis facilitator)splicing factor ESS-2 homologDiGeorge syndrome critical region gene 13DiGeorge syndrome critical region gene 14DiGeorge syndrome critical region gene DGSIDiGeorge syndrome gene HDiGeorge syndrome gene IProtein DGCR13diGeorge syndrome protein Hprot
Modification date2020031320200320
UniProtAcc

Q9BXK5

.
Ensembl transtripts involved in fusion geneENST00000337612, ENST00000543133, 
ENST00000317582, ENST00000355028, 
ENST00000399782, ENST00000418951, 
ENST00000493680, ENST00000485631, 
ENST00000538149, 		ENST00000252137, 
Fusion gene scores* DoF score17 X 18 X 10=30603 X 3 X 3=27
# samples 233
** MAII scorelog2(23/3060*10)=-3.73382588663564
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: BCL2L13 [Title/Abstract] AND DGCR14 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBCL2L13(18166087)-DGCR14(19124945), # samples:4
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across BCL2L13 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DGCR14 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCSTCGA-N6-A4VE-01ABCL2L13chr22

18166087

-DGCR14chr22

19124945

-
ChimerDB4UCSTCGA-N6-A4VE-01ABCL2L13chr22

18166087

+DGCR14chr22

19124945

-
ChimerDB4UCSTCGA-N6-A4VEBCL2L13chr22

18166087

+DGCR14chr22

19124945

-


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Fusion Gene ORF analysis for BCL2L13-DGCR14

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000337612ENST00000252137BCL2L13chr22

18166087

+DGCR14chr22

19124945

-
5UTR-3CDSENST00000543133ENST00000252137BCL2L13chr22

18166087

+DGCR14chr22

19124945

-
In-frameENST00000317582ENST00000252137BCL2L13chr22

18166087

+DGCR14chr22

19124945

-
In-frameENST00000355028ENST00000252137BCL2L13chr22

18166087

+DGCR14chr22

19124945

-
In-frameENST00000399782ENST00000252137BCL2L13chr22

18166087

+DGCR14chr22

19124945

-
In-frameENST00000418951ENST00000252137BCL2L13chr22

18166087

+DGCR14chr22

19124945

-
In-frameENST00000493680ENST00000252137BCL2L13chr22

18166087

+DGCR14chr22

19124945

-
intron-3CDSENST00000485631ENST00000252137BCL2L13chr22

18166087

+DGCR14chr22

19124945

-
intron-3CDSENST00000538149ENST00000252137BCL2L13chr22

18166087

+DGCR14chr22

19124945

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000399782BCL2L13chr2218166087+ENST00000252137DGCR14chr2219124945-539196842693193358
ENST00000317582BCL2L13chr2218166087+ENST00000252137DGCR14chr2219124945-499957638772801358
ENST00000493680BCL2L13chr2218166087+ENST00000252137DGCR14chr2219124945-481739436952619358
ENST00000355028BCL2L13chr2218166087+ENST00000252137DGCR14chr2219124945-477835536562580358
ENST00000418951BCL2L13chr2218166087+ENST00000252137DGCR14chr2219124945-465222935302454358

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000399782ENST00000252137BCL2L13chr2218166087+DGCR14chr2219124945-0.0045311880.99546885
ENST00000317582ENST00000252137BCL2L13chr2218166087+DGCR14chr2219124945-0.0052412110.9947588
ENST00000493680ENST00000252137BCL2L13chr2218166087+DGCR14chr2219124945-0.0059313930.9940686
ENST00000355028ENST00000252137BCL2L13chr2218166087+DGCR14chr2219124945-0.0059949030.99400514
ENST00000418951ENST00000252137BCL2L13chr2218166087+DGCR14chr2219124945-0.0058369790.994163

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Fusion Genomic Features for BCL2L13-DGCR14


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for BCL2L13-DGCR14


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:18166087/chr22:19124945)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BCL2L13

Q9BXK5

.
FUNCTION: May promote the activation of caspase-3 and apoptosis.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000317582+3714_3076486.0MotifNote=BH4
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000399782+4714_3076202.0MotifNote=BH4
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000493680+3614_3076202.0MotifNote=BH4

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000317582+37207_21276486.0Compositional biasNote=Poly-Glu
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000317582+37311_42476486.0Compositional biasNote=Glu-rich
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000337612+35207_2120324.0Compositional biasNote=Poly-Glu
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000337612+35311_4240324.0Compositional biasNote=Glu-rich
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000399782+47207_21276202.0Compositional biasNote=Poly-Glu
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000399782+47311_42476202.0Compositional biasNote=Glu-rich
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000493680+36207_21276202.0Compositional biasNote=Poly-Glu
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000493680+36311_42476202.0Compositional biasNote=Glu-rich
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000543133+36207_2120324.0Compositional biasNote=Poly-Glu
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000543133+36311_4240324.0Compositional biasNote=Glu-rich
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000317582+37100_11676486.0MotifNote=BH3
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000317582+37147_15776486.0MotifNote=BH1
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000317582+37193_20676486.0MotifNote=BH2
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000337612+35100_1160324.0MotifNote=BH3
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000337612+35147_1570324.0MotifNote=BH1
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000337612+3514_300324.0MotifNote=BH4
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000337612+35193_2060324.0MotifNote=BH2
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000399782+47100_11676202.0MotifNote=BH3
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000399782+47147_15776202.0MotifNote=BH1
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000399782+47193_20676202.0MotifNote=BH2
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000493680+36100_11676202.0MotifNote=BH3
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000493680+36147_15776202.0MotifNote=BH1
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000493680+36193_20676202.0MotifNote=BH2
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000543133+36100_1160324.0MotifNote=BH3
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000543133+36147_1570324.0MotifNote=BH1
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000543133+3614_300324.0MotifNote=BH4
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000543133+36193_2060324.0MotifNote=BH2
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000317582+37246_25676486.0RepeatNote=A
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000317582+37261_27176486.0RepeatNote=A%3B approximate
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000317582+37425_44176486.0RepeatNote=B
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000317582+37443_45976486.0RepeatNote=B%3B approximate
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000337612+35246_2560324.0RepeatNote=A
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000337612+35261_2710324.0RepeatNote=A%3B approximate
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000337612+35425_4410324.0RepeatNote=B
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000337612+35443_4590324.0RepeatNote=B%3B approximate
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000399782+47246_25676202.0RepeatNote=A
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000399782+47261_27176202.0RepeatNote=A%3B approximate
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000399782+47425_44176202.0RepeatNote=B
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000399782+47443_45976202.0RepeatNote=B%3B approximate
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000493680+36246_25676202.0RepeatNote=A
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000493680+36261_27176202.0RepeatNote=A%3B approximate
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000493680+36425_44176202.0RepeatNote=B
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000493680+36443_45976202.0RepeatNote=B%3B approximate
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000543133+36246_2560324.0RepeatNote=A
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000543133+36261_2710324.0RepeatNote=A%3B approximate
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000543133+36425_4410324.0RepeatNote=B
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000543133+36443_4590324.0RepeatNote=B%3B approximate
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000317582+37460_48076486.0TransmembraneHelical
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000337612+35460_4800324.0TransmembraneHelical
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000399782+47460_48076202.0TransmembraneHelical
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000493680+36460_48076202.0TransmembraneHelical
HgeneBCL2L13chr22:18166087chr22:19124945ENST00000543133+36460_4800324.0TransmembraneHelical


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Fusion Gene Sequence for BCL2L13-DGCR14


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>9353_9353_1_BCL2L13-DGCR14_BCL2L13_chr22_18166087_ENST00000317582_DGCR14_chr22_19124945_ENST00000252137_length(transcript)=4999nt_BP=576nt
AGATTTGGGCGGGCTAGGAGGGTTTGGGTCTTCAGGTCACATCTGGACGGAGAGACCTCCGGGGCCTCCGTTGGTCGGTCCTTCCGCTCC
GGATACCGTTCCGGATGTCAGGTAGTTCAGGTCCCGCCCCGACGCCGGCCGTGACGAAGGCACGCCGGGGTGACCTCACCCTCCAACATG
GCGGCGGCGGTAGATTAGGGCCGCGGGTCGGAGCACTCACCGCCGCTGGGGGACCCTGTCGGAAGCAACTGCCGCCGCCGCCTCTTTCAT
CTCTTCTGGGGCAGGGGCCAGGGCCAGGTTTTACACATCCATAAGTAGACCTTTTTGGAGCCTCACCAGCCAATTCAATGGCGTCCTCTT
CTACTGTGCCTCTGGGATTTCACTATGAAACAAAGTATGTTGTTCTCAGCTACTTGGGACTCCTCTCTCAAGAGAAGCTGCAAGAGCAAC
ATCTTTCCTCACCCCAAGGGGTTCAACTAGATATAGCTTCACAATCTCTGGATCAAGAAATTTTATTAAAAGTTAAAACTGAAATTGAAG
AAGAGCTAAAATCTCTGGACAAAGAAATTTCTGAAGGTGTGAACGAGTCCCCGATGATGACCTGGGGGGAGGTTGAGAACACACCCTTGA
GAGTTGAAGGGTCGGAAACGCCCTACGTGGACAGGACACCCGGCCCAGCTTTTAAGATCCTGGAGCCAGGCCGCAGGGAGCGGCTGGGTC
TGAAGATGGCCAACGAGGCCGCTGCCAAGAACCGGGCCAAGAAGCAGGAAGCCTTGCGGAGAGTGACGGAGAATCTGGCCAGCCTCACCC
CCAAAGGCCTGAGCCCAGCCATGTCGCCAGCCCTACAGCGCCTTGTGAGCAGGACGGCCAGCAAGTACACAGACCGGGCCCTGCGGGCCA
GCTACACACCATCCCCAGCACGCTCCACCCACCTCAAGACCCCGGCCAGTGGGCTGCAGACCCCCACAAGCACACCGGCGCCTGGCTCTG
CCACACGCACCCCTCTCACACAGGACCCGGCCTCCATCACGGACAACCTGCTGCAGCTCCCTGCCCGGCGCAAAGCTTCGGACTTCTTTT
AGAGCCAGGCCTGGGCTGGGCTCATAGACGCTTCACAGAGCCTGCAGGGCAGCTGTACACCCAGCAGAGGACTCCAGCCTTCTCGGGGCC
CAGGCCTGGGCCAGAAGCTGTTGACCATACCAGGAGTCACTGGAGAAAGGGGCTGTGCTGGGGCCAGACTGGCACAAGGCACTCGTGCCC
ACACCACACCCCAGGGCCTTGCCAAGCTGTTTGCTGTTTAATTGGCCCCTTGAACTGTCATTAAAGAACACCTAGGTACAGTCTGGGGGG
TTGCCTCTCCATCTTGCTCCCCACACGAGCCCTAGCCTTGCCCTGGGGCCTGCATCACGTCTCAGGACTGCGGGGCTTGAAGCGAGGGGC
CCCCCAGGTGAGGAAGCTGCAGGTGGGGCGGCTGTGGGAGCACCGGGTGACTGGCGTTGCTTTCTGCGGCACTCGGAACCTGTGTTCTGA
GTTGAGCTCACATCCTGCAGTGCTTTCTGCTTCTCTGGGGGGATATGAAGGAGAAACGGAGCCCTTGGAAGTTGTACCCTTAGGTTCCCC
TGCGGTTCTGGGCCCAGGTCTGCAGCCTCCACTCTGGGCTTGCCGGCTGTGAGGTGCGCTGGTTATAGGACTGTGTGGGGGCTGCATATC
AGGTGATCTCAGCTATCACCTTCTCCCAGCACCTGGCTTCCAGCTCATGGGGTGGGACTATCCCACTCACCCCTCTGCTATAGGCACTGC
CCATCTTATGCTGCTGGCCCTGGCCTCACCTGGTCACTTCCACCAACAGGAGCTCCCAGATAACAGTGGGTTGCTGGACAGATCAGGCTG
GGACTCTTAAGGGGTGGGGGACGTGGGGCCTTCAGTGCTTTATCCCCTAGGAAAGGGTGCACGTTATCCCAAGGGAGCCCCCAGGAAGTG
GGGAGGGAGGGGGGAGGAGCATGTCTAGGTGCTGACCACCTGGAGCACTTGGCCAGCAAGTGGGCCGCATGCTTTGGGAGCAATGGGTGA
CCCAGCAGGAAGCACAAAAGACCGGCCAGTGTGCCATCATCAAGGGCTGCTGAGCAGCTTGAAGAGCCACTGGGTGGGGAGGGCACACGG
GGAGGTCTCAGCTGGGGCTGCCCCTGGAGGACAGGGCAGGGAACTTGAGGGCTGAGGACAGAAATCTCACATGACTCCAGGAAATAGAGG
AAGAGGAGGATGCTGAGCGAGGGATTGTGAGGGAGTGGGGGTAGGTCAGAGGGGGCTGAACTGCAGGAAGCCAGGGGGAGTCGTGGACCA
CTGGAGCTGGCCAGCCCCAGGGCATTGGGGACAAGGCCAGGTCAGAGGGAGACAGTGTGGGCCTGGTGGGTGGACCCTGGCAGAGGCCCT
CTTGTCCCCCACAAGGCCAGGCCACACTGTGATTCTGCCTGTACCTGAGCATCTGTCCTGTGCTCCTAGGCCGGAGACCACTGTGTGTCA
GGTGGGGCGGTTGGCTGAGTCCCAGAGAAAAACACTCCTCACTGGGCACTCTTGATGCTTGCACACACCCTGTGGTTTATTTGGTGGTCA
GTAAGGAACGTCTTTGCTGCTAAGTGGAAGAAAGCTAATGGAACGTAATCAAAATAGTGGTTTAATTGACGAATTTTACTTGCACCTGTG
CCTTCTTCAGATCCTACCTGCCTACTTAGTTTACGTGAAGGCCGACTGCACCATGCCCCCCAACCCCGACCCCCACCACACACAACGGGG
CCATTGTCATGCTAGGTGCTTGCTTTCCCCACCTCAGCTCCGGAGATGTGATGGTCTTTGGCCCTGGAGGTCTCGGCCAGCCTGTCCTCC
ATCCTGTTCTCGTTCTCGGGCACCACCAGCAGCCGGTGCTGGGTTTTGGCTCCAAGCTTGTGGTCGGGCCGGTGGTCGGGCCTCAAGCCT
GTCTTGGTGTCCAGTTTGCACTCAGCGCGGTACTTGCCCTCCCCCTCCCTCTTGAAGGAGGCAGAAGACGTGGCTTTGGGCTTGGGGGGC
TGCAGCCACGAGTGGCTGAGGATCTCATCGATGTGGAGCCGCTGGCTGACGTCGGGCTGCAGCATGCGGTAGATGAGGTCCTTGCACTCG
CAGGTCAGGTTCTTGGAGCGCGGGAAGTCCACACGGTGCTCCTTCTGGATACGCAGCATCTTCCTGATGTCGGAGTCGTCATAGGGCATG
GAGCCGCAGACCATGATGTACAGGATCACGCCCAGGCTCCAGATGTCATACACCTTGGGCTGGTAGGGGATGCTCTGCAGCACCTCGGGG
GCTGCATATGCTGCCGACCCGCAGAAGGTCTTGCTGAGGATGATGCGCCCATTGCTGTCCCGCAGGCAGCGCTTGGAGAAGCCAAAGTCA
GACAGCTTGATGTTGAAGTCCTTGTCGAGGAGAAGGTTCTCGCACTTGAGGTCCCGGTGGACGATGTCCAGGTCGTGGCAGTACTTGACG
GCGGAGGAGAGCTGTCGGAACATCTTGCGTGCCACGTCCTCATGCAGGGCTCCCTGGCACTTGATGAACTCGAGGAGGTCGCCCTGGACG
CCAAGCTCCATGATGATGTAGATCCGTCCGTCAGAGGTCTCAAAGATCTCGTAAGTCTTGATGATGGAGCCGTGGTTGACAGTTGCCAGG
ATGTCCATCTCCCGAGGAAGGAATCTCTCCACAAAGTCAGTAGGTGTTTTCTTGCGGTCGATGATCTTGACAGCCACATTGAACTTGAGG
CGCTCAGAGTAGGCAGATTTGACTTTTGCGTAGGAACCCTTGCCAAGATTGATGCCTACGATGTAACCCTTCTTCCTTAGGACTGTGGCA
TCGTCCATGGTGCCAGGAGCGACTGGCGCCGCTGCCGTCTACATCCCCCCGTCATGTGGGCCAGCAGGCATTGTCCTCATTTACACTACC
GGAGGCGTCTGGCTGGGCTGCCCTGGGCTGGGCTTCGACTCAGGGGTGGAACACTCAGCATTGTCTCCGGGTGACTTCAGCCAATGAACT
CATAAAGCCAAGGAGTGGGGGCGGGGACTGGGCTGAGGGAGAACAGGGTCTCTGGAACCGTGGAAGCCAGGCTGGTCTGGCAGGAGCACC
CACTCCCCGCCCGCTGGAAGGAAGCCTGTCCCCAGGACAGGACTCTGGTGGCCCTGCTGCTGCTGCATTGGTTTCCCTGTCACAAGTCAA
GCTGGAGGGGAGGCGGCCCACGTCCAGCCTGTTTGCATCACCTGGCTGTGGGGACTGACCCTGCATTGGTCTTTGTCCCACTAGGGTGGG
TTTCCTGCAGCTTCTTTGGCTATGAAGAAAAGCACCCCCAGGGCTGTGTCCTTGGTGTGGTAGGACAGTTGTCCCTGACAGTCACCCAGA
CAGGCCTGCATAGCACCCCAGTTACACAGACAGATTTCCACAGCACTGCCTTACCATTGAGCACATAGTTAAATCTAGGGAAATCAGTGC
CCAGACATCAAAGCTAGAAATGAAACATGGTCAGCAGGAGCCTTGCATGGGCTTCTCTTTTGCTGGAGCAAGCCAAAATAATAGGAACGG
TTTTACATTCCTAGTGCCAGGACCCATCTCGGGTCGACAAAATCTGAAGACAAGTTAAGGGAACAGGCAGCTGTTTGAATAGATCAATTG
GATAGTCTAAGGCAGCTCTCTGGACCAAGCTGTAAAGGAGATACAATCGAAATAATCACTCCGGTACCACAGTAGACAGGCCTTGAAGGC
ACTGGGCCCCTTTTAATCGGACTTAGCAAGCATTTTTTTTGCCTCTGACCTTCTCCTTGGAACAAAATTAGTTACCAGTAGACTTAGGTG
ATTGCTGTACTGCATGTAGGCACATAACCCCAACCTATATAAACAGTAAGAAAATTGTAGCACTTTGAGTTGGTCTGCTGGAATTATCTC

>9353_9353_1_BCL2L13-DGCR14_BCL2L13_chr22_18166087_ENST00000317582_DGCR14_chr22_19124945_ENST00000252137_length(amino acids)=358AA_BP=
MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIM
ELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHS

--------------------------------------------------------------
>9353_9353_2_BCL2L13-DGCR14_BCL2L13_chr22_18166087_ENST00000355028_DGCR14_chr22_19124945_ENST00000252137_length(transcript)=4778nt_BP=355nt
GCCGCTGGGGGACCCTGTCGGAAGCAACTGCCGCCGCCGCCTCTTTCATCTCTTCTGGGGCAGGGGCCAGGGCCAGGTTTTACACATCCA
TAAGTAGACCTTTTTGGAGCCTCACCAGCCAATTCAATGGCGTCCTCTTCTACTGTGCCTCTGGGATTTCACTATGAAACAAAGTATGTT
GTTCTCAGCTACTTGGGACTCCTCTCTCAAGAGAAGCTGCAAGAGCAACATCTTTCCTCACCCCAAGGGGTTCAACTAGATATAGCTTCA
CAATCTCTGGATCAAGAAATTTTATTAAAAGTTAAAACTGAAATTGAAGAAGAGCTAAAATCTCTGGACAAAGAAATTTCTGAAGGTGTG
AACGAGTCCCCGATGATGACCTGGGGGGAGGTTGAGAACACACCCTTGAGAGTTGAAGGGTCGGAAACGCCCTACGTGGACAGGACACCC
GGCCCAGCTTTTAAGATCCTGGAGCCAGGCCGCAGGGAGCGGCTGGGTCTGAAGATGGCCAACGAGGCCGCTGCCAAGAACCGGGCCAAG
AAGCAGGAAGCCTTGCGGAGAGTGACGGAGAATCTGGCCAGCCTCACCCCCAAAGGCCTGAGCCCAGCCATGTCGCCAGCCCTACAGCGC
CTTGTGAGCAGGACGGCCAGCAAGTACACAGACCGGGCCCTGCGGGCCAGCTACACACCATCCCCAGCACGCTCCACCCACCTCAAGACC
CCGGCCAGTGGGCTGCAGACCCCCACAAGCACACCGGCGCCTGGCTCTGCCACACGCACCCCTCTCACACAGGACCCGGCCTCCATCACG
GACAACCTGCTGCAGCTCCCTGCCCGGCGCAAAGCTTCGGACTTCTTTTAGAGCCAGGCCTGGGCTGGGCTCATAGACGCTTCACAGAGC
CTGCAGGGCAGCTGTACACCCAGCAGAGGACTCCAGCCTTCTCGGGGCCCAGGCCTGGGCCAGAAGCTGTTGACCATACCAGGAGTCACT
GGAGAAAGGGGCTGTGCTGGGGCCAGACTGGCACAAGGCACTCGTGCCCACACCACACCCCAGGGCCTTGCCAAGCTGTTTGCTGTTTAA
TTGGCCCCTTGAACTGTCATTAAAGAACACCTAGGTACAGTCTGGGGGGTTGCCTCTCCATCTTGCTCCCCACACGAGCCCTAGCCTTGC
CCTGGGGCCTGCATCACGTCTCAGGACTGCGGGGCTTGAAGCGAGGGGCCCCCCAGGTGAGGAAGCTGCAGGTGGGGCGGCTGTGGGAGC
ACCGGGTGACTGGCGTTGCTTTCTGCGGCACTCGGAACCTGTGTTCTGAGTTGAGCTCACATCCTGCAGTGCTTTCTGCTTCTCTGGGGG
GATATGAAGGAGAAACGGAGCCCTTGGAAGTTGTACCCTTAGGTTCCCCTGCGGTTCTGGGCCCAGGTCTGCAGCCTCCACTCTGGGCTT
GCCGGCTGTGAGGTGCGCTGGTTATAGGACTGTGTGGGGGCTGCATATCAGGTGATCTCAGCTATCACCTTCTCCCAGCACCTGGCTTCC
AGCTCATGGGGTGGGACTATCCCACTCACCCCTCTGCTATAGGCACTGCCCATCTTATGCTGCTGGCCCTGGCCTCACCTGGTCACTTCC
ACCAACAGGAGCTCCCAGATAACAGTGGGTTGCTGGACAGATCAGGCTGGGACTCTTAAGGGGTGGGGGACGTGGGGCCTTCAGTGCTTT
ATCCCCTAGGAAAGGGTGCACGTTATCCCAAGGGAGCCCCCAGGAAGTGGGGAGGGAGGGGGGAGGAGCATGTCTAGGTGCTGACCACCT
GGAGCACTTGGCCAGCAAGTGGGCCGCATGCTTTGGGAGCAATGGGTGACCCAGCAGGAAGCACAAAAGACCGGCCAGTGTGCCATCATC
AAGGGCTGCTGAGCAGCTTGAAGAGCCACTGGGTGGGGAGGGCACACGGGGAGGTCTCAGCTGGGGCTGCCCCTGGAGGACAGGGCAGGG
AACTTGAGGGCTGAGGACAGAAATCTCACATGACTCCAGGAAATAGAGGAAGAGGAGGATGCTGAGCGAGGGATTGTGAGGGAGTGGGGG
TAGGTCAGAGGGGGCTGAACTGCAGGAAGCCAGGGGGAGTCGTGGACCACTGGAGCTGGCCAGCCCCAGGGCATTGGGGACAAGGCCAGG
TCAGAGGGAGACAGTGTGGGCCTGGTGGGTGGACCCTGGCAGAGGCCCTCTTGTCCCCCACAAGGCCAGGCCACACTGTGATTCTGCCTG
TACCTGAGCATCTGTCCTGTGCTCCTAGGCCGGAGACCACTGTGTGTCAGGTGGGGCGGTTGGCTGAGTCCCAGAGAAAAACACTCCTCA
CTGGGCACTCTTGATGCTTGCACACACCCTGTGGTTTATTTGGTGGTCAGTAAGGAACGTCTTTGCTGCTAAGTGGAAGAAAGCTAATGG
AACGTAATCAAAATAGTGGTTTAATTGACGAATTTTACTTGCACCTGTGCCTTCTTCAGATCCTACCTGCCTACTTAGTTTACGTGAAGG
CCGACTGCACCATGCCCCCCAACCCCGACCCCCACCACACACAACGGGGCCATTGTCATGCTAGGTGCTTGCTTTCCCCACCTCAGCTCC
GGAGATGTGATGGTCTTTGGCCCTGGAGGTCTCGGCCAGCCTGTCCTCCATCCTGTTCTCGTTCTCGGGCACCACCAGCAGCCGGTGCTG
GGTTTTGGCTCCAAGCTTGTGGTCGGGCCGGTGGTCGGGCCTCAAGCCTGTCTTGGTGTCCAGTTTGCACTCAGCGCGGTACTTGCCCTC
CCCCTCCCTCTTGAAGGAGGCAGAAGACGTGGCTTTGGGCTTGGGGGGCTGCAGCCACGAGTGGCTGAGGATCTCATCGATGTGGAGCCG
CTGGCTGACGTCGGGCTGCAGCATGCGGTAGATGAGGTCCTTGCACTCGCAGGTCAGGTTCTTGGAGCGCGGGAAGTCCACACGGTGCTC
CTTCTGGATACGCAGCATCTTCCTGATGTCGGAGTCGTCATAGGGCATGGAGCCGCAGACCATGATGTACAGGATCACGCCCAGGCTCCA
GATGTCATACACCTTGGGCTGGTAGGGGATGCTCTGCAGCACCTCGGGGGCTGCATATGCTGCCGACCCGCAGAAGGTCTTGCTGAGGAT
GATGCGCCCATTGCTGTCCCGCAGGCAGCGCTTGGAGAAGCCAAAGTCAGACAGCTTGATGTTGAAGTCCTTGTCGAGGAGAAGGTTCTC
GCACTTGAGGTCCCGGTGGACGATGTCCAGGTCGTGGCAGTACTTGACGGCGGAGGAGAGCTGTCGGAACATCTTGCGTGCCACGTCCTC
ATGCAGGGCTCCCTGGCACTTGATGAACTCGAGGAGGTCGCCCTGGACGCCAAGCTCCATGATGATGTAGATCCGTCCGTCAGAGGTCTC
AAAGATCTCGTAAGTCTTGATGATGGAGCCGTGGTTGACAGTTGCCAGGATGTCCATCTCCCGAGGAAGGAATCTCTCCACAAAGTCAGT
AGGTGTTTTCTTGCGGTCGATGATCTTGACAGCCACATTGAACTTGAGGCGCTCAGAGTAGGCAGATTTGACTTTTGCGTAGGAACCCTT
GCCAAGATTGATGCCTACGATGTAACCCTTCTTCCTTAGGACTGTGGCATCGTCCATGGTGCCAGGAGCGACTGGCGCCGCTGCCGTCTA
CATCCCCCCGTCATGTGGGCCAGCAGGCATTGTCCTCATTTACACTACCGGAGGCGTCTGGCTGGGCTGCCCTGGGCTGGGCTTCGACTC
AGGGGTGGAACACTCAGCATTGTCTCCGGGTGACTTCAGCCAATGAACTCATAAAGCCAAGGAGTGGGGGCGGGGACTGGGCTGAGGGAG
AACAGGGTCTCTGGAACCGTGGAAGCCAGGCTGGTCTGGCAGGAGCACCCACTCCCCGCCCGCTGGAAGGAAGCCTGTCCCCAGGACAGG
ACTCTGGTGGCCCTGCTGCTGCTGCATTGGTTTCCCTGTCACAAGTCAAGCTGGAGGGGAGGCGGCCCACGTCCAGCCTGTTTGCATCAC
CTGGCTGTGGGGACTGACCCTGCATTGGTCTTTGTCCCACTAGGGTGGGTTTCCTGCAGCTTCTTTGGCTATGAAGAAAAGCACCCCCAG
GGCTGTGTCCTTGGTGTGGTAGGACAGTTGTCCCTGACAGTCACCCAGACAGGCCTGCATAGCACCCCAGTTACACAGACAGATTTCCAC
AGCACTGCCTTACCATTGAGCACATAGTTAAATCTAGGGAAATCAGTGCCCAGACATCAAAGCTAGAAATGAAACATGGTCAGCAGGAGC
CTTGCATGGGCTTCTCTTTTGCTGGAGCAAGCCAAAATAATAGGAACGGTTTTACATTCCTAGTGCCAGGACCCATCTCGGGTCGACAAA
ATCTGAAGACAAGTTAAGGGAACAGGCAGCTGTTTGAATAGATCAATTGGATAGTCTAAGGCAGCTCTCTGGACCAAGCTGTAAAGGAGA
TACAATCGAAATAATCACTCCGGTACCACAGTAGACAGGCCTTGAAGGCACTGGGCCCCTTTTAATCGGACTTAGCAAGCATTTTTTTTG
CCTCTGACCTTCTCCTTGGAACAAAATTAGTTACCAGTAGACTTAGGTGATTGCTGTACTGCATGTAGGCACATAACCCCAACCTATATA
AACAGTAAGAAAATTGTAGCACTTTGAGTTGGTCTGCTGGAATTATCTCCAGCCTTCTCCCTGTATCCAGTTACAGTGATAAACTCCCTT

>9353_9353_2_BCL2L13-DGCR14_BCL2L13_chr22_18166087_ENST00000355028_DGCR14_chr22_19124945_ENST00000252137_length(amino acids)=358AA_BP=
MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIM
ELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHS

--------------------------------------------------------------
>9353_9353_3_BCL2L13-DGCR14_BCL2L13_chr22_18166087_ENST00000399782_DGCR14_chr22_19124945_ENST00000252137_length(transcript)=5391nt_BP=968nt
TCCTAAACTGGGATCTTGGGTAGGAGGAAGAAAAGATAAGGAGTTCCTCTATCTGAAATTAGTCGGGCTGTTTTGAGGAGTACTGGTTAG
ATACCTTCCGATACTCCTCCAAAGAACTCTCGGATTCAAGTAAACAAACATCCATTAATACAAGTTAAGTATGTTCCAGGCGCTGTGTGT
TCCAGGTACTGTTAACAAAAGCGGGTTACTAGTTAAGACTTCCTTCATGCCCTGGCGCCTCTGCTCAGCCAGTTCCCTTCGCCTAGGAGG
ACCTCTCTACACCACCCCGCTATATTCCCTCCCCGGAATTCCTTCCCAACCTTCAAGGACCATCTGCCCCAACTAGTGGCGAACATCGAG
GCTGTCGTGACTGTGTAGATACTTATTTGACCTGCTCCCTTGGCAAACACTTGAAACGCAATACATGTTTGTGGAACTGAACATAGCCTG
TGCATGCAGCAAGGCTTCTTTCCCTGGAATCGCCTGCCCTTCCTCCAACACAGCGACCAGCCGGTCAGAATCCCAACCCCTCGACTCCGG
AAATGATCTGAGAGACGGAACTTCCGAACGTCGCAATCAGATTTGGGCGGGCTAGGAGGGTTTGGGTCTTCAGGTCACATCTGGACGGAG
AGACCTCCGGGGCCTCCGTTGGTCGGTCCTTCCGCTCCGGATACCGTTCCGGATGTCAGGTTTTACACATCCATAAGTAGACCTTTTTGG
AGCCTCACCAGCCAATTCAATGGCGTCCTCTTCTACTGTGCCTCTGGGATTTCACTATGAAACAAAGTATGTTGTTCTCAGCTACTTGGG
ACTCCTCTCTCAAGAGAAGCTGCAAGAGCAACATCTTTCCTCACCCCAAGGGGTTCAACTAGATATAGCTTCACAATCTCTGGATCAAGA
AATTTTATTAAAAGTTAAAACTGAAATTGAAGAAGAGCTAAAATCTCTGGACAAAGAAATTTCTGAAGGTGTGAACGAGTCCCCGATGAT
GACCTGGGGGGAGGTTGAGAACACACCCTTGAGAGTTGAAGGGTCGGAAACGCCCTACGTGGACAGGACACCCGGCCCAGCTTTTAAGAT
CCTGGAGCCAGGCCGCAGGGAGCGGCTGGGTCTGAAGATGGCCAACGAGGCCGCTGCCAAGAACCGGGCCAAGAAGCAGGAAGCCTTGCG
GAGAGTGACGGAGAATCTGGCCAGCCTCACCCCCAAAGGCCTGAGCCCAGCCATGTCGCCAGCCCTACAGCGCCTTGTGAGCAGGACGGC
CAGCAAGTACACAGACCGGGCCCTGCGGGCCAGCTACACACCATCCCCAGCACGCTCCACCCACCTCAAGACCCCGGCCAGTGGGCTGCA
GACCCCCACAAGCACACCGGCGCCTGGCTCTGCCACACGCACCCCTCTCACACAGGACCCGGCCTCCATCACGGACAACCTGCTGCAGCT
CCCTGCCCGGCGCAAAGCTTCGGACTTCTTTTAGAGCCAGGCCTGGGCTGGGCTCATAGACGCTTCACAGAGCCTGCAGGGCAGCTGTAC
ACCCAGCAGAGGACTCCAGCCTTCTCGGGGCCCAGGCCTGGGCCAGAAGCTGTTGACCATACCAGGAGTCACTGGAGAAAGGGGCTGTGC
TGGGGCCAGACTGGCACAAGGCACTCGTGCCCACACCACACCCCAGGGCCTTGCCAAGCTGTTTGCTGTTTAATTGGCCCCTTGAACTGT
CATTAAAGAACACCTAGGTACAGTCTGGGGGGTTGCCTCTCCATCTTGCTCCCCACACGAGCCCTAGCCTTGCCCTGGGGCCTGCATCAC
GTCTCAGGACTGCGGGGCTTGAAGCGAGGGGCCCCCCAGGTGAGGAAGCTGCAGGTGGGGCGGCTGTGGGAGCACCGGGTGACTGGCGTT
GCTTTCTGCGGCACTCGGAACCTGTGTTCTGAGTTGAGCTCACATCCTGCAGTGCTTTCTGCTTCTCTGGGGGGATATGAAGGAGAAACG
GAGCCCTTGGAAGTTGTACCCTTAGGTTCCCCTGCGGTTCTGGGCCCAGGTCTGCAGCCTCCACTCTGGGCTTGCCGGCTGTGAGGTGCG
CTGGTTATAGGACTGTGTGGGGGCTGCATATCAGGTGATCTCAGCTATCACCTTCTCCCAGCACCTGGCTTCCAGCTCATGGGGTGGGAC
TATCCCACTCACCCCTCTGCTATAGGCACTGCCCATCTTATGCTGCTGGCCCTGGCCTCACCTGGTCACTTCCACCAACAGGAGCTCCCA
GATAACAGTGGGTTGCTGGACAGATCAGGCTGGGACTCTTAAGGGGTGGGGGACGTGGGGCCTTCAGTGCTTTATCCCCTAGGAAAGGGT
GCACGTTATCCCAAGGGAGCCCCCAGGAAGTGGGGAGGGAGGGGGGAGGAGCATGTCTAGGTGCTGACCACCTGGAGCACTTGGCCAGCA
AGTGGGCCGCATGCTTTGGGAGCAATGGGTGACCCAGCAGGAAGCACAAAAGACCGGCCAGTGTGCCATCATCAAGGGCTGCTGAGCAGC
TTGAAGAGCCACTGGGTGGGGAGGGCACACGGGGAGGTCTCAGCTGGGGCTGCCCCTGGAGGACAGGGCAGGGAACTTGAGGGCTGAGGA
CAGAAATCTCACATGACTCCAGGAAATAGAGGAAGAGGAGGATGCTGAGCGAGGGATTGTGAGGGAGTGGGGGTAGGTCAGAGGGGGCTG
AACTGCAGGAAGCCAGGGGGAGTCGTGGACCACTGGAGCTGGCCAGCCCCAGGGCATTGGGGACAAGGCCAGGTCAGAGGGAGACAGTGT
GGGCCTGGTGGGTGGACCCTGGCAGAGGCCCTCTTGTCCCCCACAAGGCCAGGCCACACTGTGATTCTGCCTGTACCTGAGCATCTGTCC
TGTGCTCCTAGGCCGGAGACCACTGTGTGTCAGGTGGGGCGGTTGGCTGAGTCCCAGAGAAAAACACTCCTCACTGGGCACTCTTGATGC
TTGCACACACCCTGTGGTTTATTTGGTGGTCAGTAAGGAACGTCTTTGCTGCTAAGTGGAAGAAAGCTAATGGAACGTAATCAAAATAGT
GGTTTAATTGACGAATTTTACTTGCACCTGTGCCTTCTTCAGATCCTACCTGCCTACTTAGTTTACGTGAAGGCCGACTGCACCATGCCC
CCCAACCCCGACCCCCACCACACACAACGGGGCCATTGTCATGCTAGGTGCTTGCTTTCCCCACCTCAGCTCCGGAGATGTGATGGTCTT
TGGCCCTGGAGGTCTCGGCCAGCCTGTCCTCCATCCTGTTCTCGTTCTCGGGCACCACCAGCAGCCGGTGCTGGGTTTTGGCTCCAAGCT
TGTGGTCGGGCCGGTGGTCGGGCCTCAAGCCTGTCTTGGTGTCCAGTTTGCACTCAGCGCGGTACTTGCCCTCCCCCTCCCTCTTGAAGG
AGGCAGAAGACGTGGCTTTGGGCTTGGGGGGCTGCAGCCACGAGTGGCTGAGGATCTCATCGATGTGGAGCCGCTGGCTGACGTCGGGCT
GCAGCATGCGGTAGATGAGGTCCTTGCACTCGCAGGTCAGGTTCTTGGAGCGCGGGAAGTCCACACGGTGCTCCTTCTGGATACGCAGCA
TCTTCCTGATGTCGGAGTCGTCATAGGGCATGGAGCCGCAGACCATGATGTACAGGATCACGCCCAGGCTCCAGATGTCATACACCTTGG
GCTGGTAGGGGATGCTCTGCAGCACCTCGGGGGCTGCATATGCTGCCGACCCGCAGAAGGTCTTGCTGAGGATGATGCGCCCATTGCTGT
CCCGCAGGCAGCGCTTGGAGAAGCCAAAGTCAGACAGCTTGATGTTGAAGTCCTTGTCGAGGAGAAGGTTCTCGCACTTGAGGTCCCGGT
GGACGATGTCCAGGTCGTGGCAGTACTTGACGGCGGAGGAGAGCTGTCGGAACATCTTGCGTGCCACGTCCTCATGCAGGGCTCCCTGGC
ACTTGATGAACTCGAGGAGGTCGCCCTGGACGCCAAGCTCCATGATGATGTAGATCCGTCCGTCAGAGGTCTCAAAGATCTCGTAAGTCT
TGATGATGGAGCCGTGGTTGACAGTTGCCAGGATGTCCATCTCCCGAGGAAGGAATCTCTCCACAAAGTCAGTAGGTGTTTTCTTGCGGT
CGATGATCTTGACAGCCACATTGAACTTGAGGCGCTCAGAGTAGGCAGATTTGACTTTTGCGTAGGAACCCTTGCCAAGATTGATGCCTA
CGATGTAACCCTTCTTCCTTAGGACTGTGGCATCGTCCATGGTGCCAGGAGCGACTGGCGCCGCTGCCGTCTACATCCCCCCGTCATGTG
GGCCAGCAGGCATTGTCCTCATTTACACTACCGGAGGCGTCTGGCTGGGCTGCCCTGGGCTGGGCTTCGACTCAGGGGTGGAACACTCAG
CATTGTCTCCGGGTGACTTCAGCCAATGAACTCATAAAGCCAAGGAGTGGGGGCGGGGACTGGGCTGAGGGAGAACAGGGTCTCTGGAAC
CGTGGAAGCCAGGCTGGTCTGGCAGGAGCACCCACTCCCCGCCCGCTGGAAGGAAGCCTGTCCCCAGGACAGGACTCTGGTGGCCCTGCT
GCTGCTGCATTGGTTTCCCTGTCACAAGTCAAGCTGGAGGGGAGGCGGCCCACGTCCAGCCTGTTTGCATCACCTGGCTGTGGGGACTGA
CCCTGCATTGGTCTTTGTCCCACTAGGGTGGGTTTCCTGCAGCTTCTTTGGCTATGAAGAAAAGCACCCCCAGGGCTGTGTCCTTGGTGT
GGTAGGACAGTTGTCCCTGACAGTCACCCAGACAGGCCTGCATAGCACCCCAGTTACACAGACAGATTTCCACAGCACTGCCTTACCATT
GAGCACATAGTTAAATCTAGGGAAATCAGTGCCCAGACATCAAAGCTAGAAATGAAACATGGTCAGCAGGAGCCTTGCATGGGCTTCTCT
TTTGCTGGAGCAAGCCAAAATAATAGGAACGGTTTTACATTCCTAGTGCCAGGACCCATCTCGGGTCGACAAAATCTGAAGACAAGTTAA
GGGAACAGGCAGCTGTTTGAATAGATCAATTGGATAGTCTAAGGCAGCTCTCTGGACCAAGCTGTAAAGGAGATACAATCGAAATAATCA
CTCCGGTACCACAGTAGACAGGCCTTGAAGGCACTGGGCCCCTTTTAATCGGACTTAGCAAGCATTTTTTTTGCCTCTGACCTTCTCCTT
GGAACAAAATTAGTTACCAGTAGACTTAGGTGATTGCTGTACTGCATGTAGGCACATAACCCCAACCTATATAAACAGTAAGAAAATTGT

>9353_9353_3_BCL2L13-DGCR14_BCL2L13_chr22_18166087_ENST00000399782_DGCR14_chr22_19124945_ENST00000252137_length(amino acids)=358AA_BP=
MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIM
ELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHS

--------------------------------------------------------------
>9353_9353_4_BCL2L13-DGCR14_BCL2L13_chr22_18166087_ENST00000418951_DGCR14_chr22_19124945_ENST00000252137_length(transcript)=4652nt_BP=229nt
ATGGCGTCCTCTTCTACTGTGCCTCTGGGATTTCACTATGAAACAAAGTATGTTGTTCTCAGCTACTTGGGACTCCTCTCTCAAGAGAAG
CTGCAAGAGCAACATCTTTCCTCACCCCAAGGGGTTCAACTAGATATAGCTTCACAATCTCTGGATCAAGAAATTTTATTAAAAGTTAAA
ACTGAAATTGAAGAAGAGCTAAAATCTCTGGACAAAGAAATTTCTGAAGGTGTGAACGAGTCCCCGATGATGACCTGGGGGGAGGTTGAG
AACACACCCTTGAGAGTTGAAGGGTCGGAAACGCCCTACGTGGACAGGACACCCGGCCCAGCTTTTAAGATCCTGGAGCCAGGCCGCAGG
GAGCGGCTGGGTCTGAAGATGGCCAACGAGGCCGCTGCCAAGAACCGGGCCAAGAAGCAGGAAGCCTTGCGGAGAGTGACGGAGAATCTG
GCCAGCCTCACCCCCAAAGGCCTGAGCCCAGCCATGTCGCCAGCCCTACAGCGCCTTGTGAGCAGGACGGCCAGCAAGTACACAGACCGG
GCCCTGCGGGCCAGCTACACACCATCCCCAGCACGCTCCACCCACCTCAAGACCCCGGCCAGTGGGCTGCAGACCCCCACAAGCACACCG
GCGCCTGGCTCTGCCACACGCACCCCTCTCACACAGGACCCGGCCTCCATCACGGACAACCTGCTGCAGCTCCCTGCCCGGCGCAAAGCT
TCGGACTTCTTTTAGAGCCAGGCCTGGGCTGGGCTCATAGACGCTTCACAGAGCCTGCAGGGCAGCTGTACACCCAGCAGAGGACTCCAG
CCTTCTCGGGGCCCAGGCCTGGGCCAGAAGCTGTTGACCATACCAGGAGTCACTGGAGAAAGGGGCTGTGCTGGGGCCAGACTGGCACAA
GGCACTCGTGCCCACACCACACCCCAGGGCCTTGCCAAGCTGTTTGCTGTTTAATTGGCCCCTTGAACTGTCATTAAAGAACACCTAGGT
ACAGTCTGGGGGGTTGCCTCTCCATCTTGCTCCCCACACGAGCCCTAGCCTTGCCCTGGGGCCTGCATCACGTCTCAGGACTGCGGGGCT
TGAAGCGAGGGGCCCCCCAGGTGAGGAAGCTGCAGGTGGGGCGGCTGTGGGAGCACCGGGTGACTGGCGTTGCTTTCTGCGGCACTCGGA
ACCTGTGTTCTGAGTTGAGCTCACATCCTGCAGTGCTTTCTGCTTCTCTGGGGGGATATGAAGGAGAAACGGAGCCCTTGGAAGTTGTAC
CCTTAGGTTCCCCTGCGGTTCTGGGCCCAGGTCTGCAGCCTCCACTCTGGGCTTGCCGGCTGTGAGGTGCGCTGGTTATAGGACTGTGTG
GGGGCTGCATATCAGGTGATCTCAGCTATCACCTTCTCCCAGCACCTGGCTTCCAGCTCATGGGGTGGGACTATCCCACTCACCCCTCTG
CTATAGGCACTGCCCATCTTATGCTGCTGGCCCTGGCCTCACCTGGTCACTTCCACCAACAGGAGCTCCCAGATAACAGTGGGTTGCTGG
ACAGATCAGGCTGGGACTCTTAAGGGGTGGGGGACGTGGGGCCTTCAGTGCTTTATCCCCTAGGAAAGGGTGCACGTTATCCCAAGGGAG
CCCCCAGGAAGTGGGGAGGGAGGGGGGAGGAGCATGTCTAGGTGCTGACCACCTGGAGCACTTGGCCAGCAAGTGGGCCGCATGCTTTGG
GAGCAATGGGTGACCCAGCAGGAAGCACAAAAGACCGGCCAGTGTGCCATCATCAAGGGCTGCTGAGCAGCTTGAAGAGCCACTGGGTGG
GGAGGGCACACGGGGAGGTCTCAGCTGGGGCTGCCCCTGGAGGACAGGGCAGGGAACTTGAGGGCTGAGGACAGAAATCTCACATGACTC
CAGGAAATAGAGGAAGAGGAGGATGCTGAGCGAGGGATTGTGAGGGAGTGGGGGTAGGTCAGAGGGGGCTGAACTGCAGGAAGCCAGGGG
GAGTCGTGGACCACTGGAGCTGGCCAGCCCCAGGGCATTGGGGACAAGGCCAGGTCAGAGGGAGACAGTGTGGGCCTGGTGGGTGGACCC
TGGCAGAGGCCCTCTTGTCCCCCACAAGGCCAGGCCACACTGTGATTCTGCCTGTACCTGAGCATCTGTCCTGTGCTCCTAGGCCGGAGA
CCACTGTGTGTCAGGTGGGGCGGTTGGCTGAGTCCCAGAGAAAAACACTCCTCACTGGGCACTCTTGATGCTTGCACACACCCTGTGGTT
TATTTGGTGGTCAGTAAGGAACGTCTTTGCTGCTAAGTGGAAGAAAGCTAATGGAACGTAATCAAAATAGTGGTTTAATTGACGAATTTT
ACTTGCACCTGTGCCTTCTTCAGATCCTACCTGCCTACTTAGTTTACGTGAAGGCCGACTGCACCATGCCCCCCAACCCCGACCCCCACC
ACACACAACGGGGCCATTGTCATGCTAGGTGCTTGCTTTCCCCACCTCAGCTCCGGAGATGTGATGGTCTTTGGCCCTGGAGGTCTCGGC
CAGCCTGTCCTCCATCCTGTTCTCGTTCTCGGGCACCACCAGCAGCCGGTGCTGGGTTTTGGCTCCAAGCTTGTGGTCGGGCCGGTGGTC
GGGCCTCAAGCCTGTCTTGGTGTCCAGTTTGCACTCAGCGCGGTACTTGCCCTCCCCCTCCCTCTTGAAGGAGGCAGAAGACGTGGCTTT
GGGCTTGGGGGGCTGCAGCCACGAGTGGCTGAGGATCTCATCGATGTGGAGCCGCTGGCTGACGTCGGGCTGCAGCATGCGGTAGATGAG
GTCCTTGCACTCGCAGGTCAGGTTCTTGGAGCGCGGGAAGTCCACACGGTGCTCCTTCTGGATACGCAGCATCTTCCTGATGTCGGAGTC
GTCATAGGGCATGGAGCCGCAGACCATGATGTACAGGATCACGCCCAGGCTCCAGATGTCATACACCTTGGGCTGGTAGGGGATGCTCTG
CAGCACCTCGGGGGCTGCATATGCTGCCGACCCGCAGAAGGTCTTGCTGAGGATGATGCGCCCATTGCTGTCCCGCAGGCAGCGCTTGGA
GAAGCCAAAGTCAGACAGCTTGATGTTGAAGTCCTTGTCGAGGAGAAGGTTCTCGCACTTGAGGTCCCGGTGGACGATGTCCAGGTCGTG
GCAGTACTTGACGGCGGAGGAGAGCTGTCGGAACATCTTGCGTGCCACGTCCTCATGCAGGGCTCCCTGGCACTTGATGAACTCGAGGAG
GTCGCCCTGGACGCCAAGCTCCATGATGATGTAGATCCGTCCGTCAGAGGTCTCAAAGATCTCGTAAGTCTTGATGATGGAGCCGTGGTT
GACAGTTGCCAGGATGTCCATCTCCCGAGGAAGGAATCTCTCCACAAAGTCAGTAGGTGTTTTCTTGCGGTCGATGATCTTGACAGCCAC
ATTGAACTTGAGGCGCTCAGAGTAGGCAGATTTGACTTTTGCGTAGGAACCCTTGCCAAGATTGATGCCTACGATGTAACCCTTCTTCCT
TAGGACTGTGGCATCGTCCATGGTGCCAGGAGCGACTGGCGCCGCTGCCGTCTACATCCCCCCGTCATGTGGGCCAGCAGGCATTGTCCT
CATTTACACTACCGGAGGCGTCTGGCTGGGCTGCCCTGGGCTGGGCTTCGACTCAGGGGTGGAACACTCAGCATTGTCTCCGGGTGACTT
CAGCCAATGAACTCATAAAGCCAAGGAGTGGGGGCGGGGACTGGGCTGAGGGAGAACAGGGTCTCTGGAACCGTGGAAGCCAGGCTGGTC
TGGCAGGAGCACCCACTCCCCGCCCGCTGGAAGGAAGCCTGTCCCCAGGACAGGACTCTGGTGGCCCTGCTGCTGCTGCATTGGTTTCCC
TGTCACAAGTCAAGCTGGAGGGGAGGCGGCCCACGTCCAGCCTGTTTGCATCACCTGGCTGTGGGGACTGACCCTGCATTGGTCTTTGTC
CCACTAGGGTGGGTTTCCTGCAGCTTCTTTGGCTATGAAGAAAAGCACCCCCAGGGCTGTGTCCTTGGTGTGGTAGGACAGTTGTCCCTG
ACAGTCACCCAGACAGGCCTGCATAGCACCCCAGTTACACAGACAGATTTCCACAGCACTGCCTTACCATTGAGCACATAGTTAAATCTA
GGGAAATCAGTGCCCAGACATCAAAGCTAGAAATGAAACATGGTCAGCAGGAGCCTTGCATGGGCTTCTCTTTTGCTGGAGCAAGCCAAA
ATAATAGGAACGGTTTTACATTCCTAGTGCCAGGACCCATCTCGGGTCGACAAAATCTGAAGACAAGTTAAGGGAACAGGCAGCTGTTTG
AATAGATCAATTGGATAGTCTAAGGCAGCTCTCTGGACCAAGCTGTAAAGGAGATACAATCGAAATAATCACTCCGGTACCACAGTAGAC
AGGCCTTGAAGGCACTGGGCCCCTTTTAATCGGACTTAGCAAGCATTTTTTTTGCCTCTGACCTTCTCCTTGGAACAAAATTAGTTACCA
GTAGACTTAGGTGATTGCTGTACTGCATGTAGGCACATAACCCCAACCTATATAAACAGTAAGAAAATTGTAGCACTTTGAGTTGGTCTG

>9353_9353_4_BCL2L13-DGCR14_BCL2L13_chr22_18166087_ENST00000418951_DGCR14_chr22_19124945_ENST00000252137_length(amino acids)=358AA_BP=
MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIM
ELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHS

--------------------------------------------------------------
>9353_9353_5_BCL2L13-DGCR14_BCL2L13_chr22_18166087_ENST00000493680_DGCR14_chr22_19124945_ENST00000252137_length(transcript)=4817nt_BP=394nt
GGCGGCGGTAGATTAGGGCCGCGGGTCGGAGCACTCACCGCCGCTGGGGGACCCTGTCGGAAGCAACTGCCGCCGCCGCCTCTTTCATCT
CTTCTGGGGCAGGGGCCAGGGCCAGGTTTTACACATCCATAAGTAGACCTTTTTGGAGCCTCACCAGCCAATTCAATGGCGTCCTCTTCT
ACTGTGCCTCTGGGATTTCACTATGAAACAAAGTATGTTGTTCTCAGCTACTTGGGACTCCTCTCTCAAGAGAAGCTGCAAGAGCAACAT
CTTTCCTCACCCCAAGGGGTTCAACTAGATATAGCTTCACAATCTCTGGATCAAGAAATTTTATTAAAAGTTAAAACTGAAATTGAAGAA
GAGCTAAAATCTCTGGACAAAGAAATTTCTGAAGGTGTGAACGAGTCCCCGATGATGACCTGGGGGGAGGTTGAGAACACACCCTTGAGA
GTTGAAGGGTCGGAAACGCCCTACGTGGACAGGACACCCGGCCCAGCTTTTAAGATCCTGGAGCCAGGCCGCAGGGAGCGGCTGGGTCTG
AAGATGGCCAACGAGGCCGCTGCCAAGAACCGGGCCAAGAAGCAGGAAGCCTTGCGGAGAGTGACGGAGAATCTGGCCAGCCTCACCCCC
AAAGGCCTGAGCCCAGCCATGTCGCCAGCCCTACAGCGCCTTGTGAGCAGGACGGCCAGCAAGTACACAGACCGGGCCCTGCGGGCCAGC
TACACACCATCCCCAGCACGCTCCACCCACCTCAAGACCCCGGCCAGTGGGCTGCAGACCCCCACAAGCACACCGGCGCCTGGCTCTGCC
ACACGCACCCCTCTCACACAGGACCCGGCCTCCATCACGGACAACCTGCTGCAGCTCCCTGCCCGGCGCAAAGCTTCGGACTTCTTTTAG
AGCCAGGCCTGGGCTGGGCTCATAGACGCTTCACAGAGCCTGCAGGGCAGCTGTACACCCAGCAGAGGACTCCAGCCTTCTCGGGGCCCA
GGCCTGGGCCAGAAGCTGTTGACCATACCAGGAGTCACTGGAGAAAGGGGCTGTGCTGGGGCCAGACTGGCACAAGGCACTCGTGCCCAC
ACCACACCCCAGGGCCTTGCCAAGCTGTTTGCTGTTTAATTGGCCCCTTGAACTGTCATTAAAGAACACCTAGGTACAGTCTGGGGGGTT
GCCTCTCCATCTTGCTCCCCACACGAGCCCTAGCCTTGCCCTGGGGCCTGCATCACGTCTCAGGACTGCGGGGCTTGAAGCGAGGGGCCC
CCCAGGTGAGGAAGCTGCAGGTGGGGCGGCTGTGGGAGCACCGGGTGACTGGCGTTGCTTTCTGCGGCACTCGGAACCTGTGTTCTGAGT
TGAGCTCACATCCTGCAGTGCTTTCTGCTTCTCTGGGGGGATATGAAGGAGAAACGGAGCCCTTGGAAGTTGTACCCTTAGGTTCCCCTG
CGGTTCTGGGCCCAGGTCTGCAGCCTCCACTCTGGGCTTGCCGGCTGTGAGGTGCGCTGGTTATAGGACTGTGTGGGGGCTGCATATCAG
GTGATCTCAGCTATCACCTTCTCCCAGCACCTGGCTTCCAGCTCATGGGGTGGGACTATCCCACTCACCCCTCTGCTATAGGCACTGCCC
ATCTTATGCTGCTGGCCCTGGCCTCACCTGGTCACTTCCACCAACAGGAGCTCCCAGATAACAGTGGGTTGCTGGACAGATCAGGCTGGG
ACTCTTAAGGGGTGGGGGACGTGGGGCCTTCAGTGCTTTATCCCCTAGGAAAGGGTGCACGTTATCCCAAGGGAGCCCCCAGGAAGTGGG
GAGGGAGGGGGGAGGAGCATGTCTAGGTGCTGACCACCTGGAGCACTTGGCCAGCAAGTGGGCCGCATGCTTTGGGAGCAATGGGTGACC
CAGCAGGAAGCACAAAAGACCGGCCAGTGTGCCATCATCAAGGGCTGCTGAGCAGCTTGAAGAGCCACTGGGTGGGGAGGGCACACGGGG
AGGTCTCAGCTGGGGCTGCCCCTGGAGGACAGGGCAGGGAACTTGAGGGCTGAGGACAGAAATCTCACATGACTCCAGGAAATAGAGGAA
GAGGAGGATGCTGAGCGAGGGATTGTGAGGGAGTGGGGGTAGGTCAGAGGGGGCTGAACTGCAGGAAGCCAGGGGGAGTCGTGGACCACT
GGAGCTGGCCAGCCCCAGGGCATTGGGGACAAGGCCAGGTCAGAGGGAGACAGTGTGGGCCTGGTGGGTGGACCCTGGCAGAGGCCCTCT
TGTCCCCCACAAGGCCAGGCCACACTGTGATTCTGCCTGTACCTGAGCATCTGTCCTGTGCTCCTAGGCCGGAGACCACTGTGTGTCAGG
TGGGGCGGTTGGCTGAGTCCCAGAGAAAAACACTCCTCACTGGGCACTCTTGATGCTTGCACACACCCTGTGGTTTATTTGGTGGTCAGT
AAGGAACGTCTTTGCTGCTAAGTGGAAGAAAGCTAATGGAACGTAATCAAAATAGTGGTTTAATTGACGAATTTTACTTGCACCTGTGCC
TTCTTCAGATCCTACCTGCCTACTTAGTTTACGTGAAGGCCGACTGCACCATGCCCCCCAACCCCGACCCCCACCACACACAACGGGGCC
ATTGTCATGCTAGGTGCTTGCTTTCCCCACCTCAGCTCCGGAGATGTGATGGTCTTTGGCCCTGGAGGTCTCGGCCAGCCTGTCCTCCAT
CCTGTTCTCGTTCTCGGGCACCACCAGCAGCCGGTGCTGGGTTTTGGCTCCAAGCTTGTGGTCGGGCCGGTGGTCGGGCCTCAAGCCTGT
CTTGGTGTCCAGTTTGCACTCAGCGCGGTACTTGCCCTCCCCCTCCCTCTTGAAGGAGGCAGAAGACGTGGCTTTGGGCTTGGGGGGCTG
CAGCCACGAGTGGCTGAGGATCTCATCGATGTGGAGCCGCTGGCTGACGTCGGGCTGCAGCATGCGGTAGATGAGGTCCTTGCACTCGCA
GGTCAGGTTCTTGGAGCGCGGGAAGTCCACACGGTGCTCCTTCTGGATACGCAGCATCTTCCTGATGTCGGAGTCGTCATAGGGCATGGA
GCCGCAGACCATGATGTACAGGATCACGCCCAGGCTCCAGATGTCATACACCTTGGGCTGGTAGGGGATGCTCTGCAGCACCTCGGGGGC
TGCATATGCTGCCGACCCGCAGAAGGTCTTGCTGAGGATGATGCGCCCATTGCTGTCCCGCAGGCAGCGCTTGGAGAAGCCAAAGTCAGA
CAGCTTGATGTTGAAGTCCTTGTCGAGGAGAAGGTTCTCGCACTTGAGGTCCCGGTGGACGATGTCCAGGTCGTGGCAGTACTTGACGGC
GGAGGAGAGCTGTCGGAACATCTTGCGTGCCACGTCCTCATGCAGGGCTCCCTGGCACTTGATGAACTCGAGGAGGTCGCCCTGGACGCC
AAGCTCCATGATGATGTAGATCCGTCCGTCAGAGGTCTCAAAGATCTCGTAAGTCTTGATGATGGAGCCGTGGTTGACAGTTGCCAGGAT
GTCCATCTCCCGAGGAAGGAATCTCTCCACAAAGTCAGTAGGTGTTTTCTTGCGGTCGATGATCTTGACAGCCACATTGAACTTGAGGCG
CTCAGAGTAGGCAGATTTGACTTTTGCGTAGGAACCCTTGCCAAGATTGATGCCTACGATGTAACCCTTCTTCCTTAGGACTGTGGCATC
GTCCATGGTGCCAGGAGCGACTGGCGCCGCTGCCGTCTACATCCCCCCGTCATGTGGGCCAGCAGGCATTGTCCTCATTTACACTACCGG
AGGCGTCTGGCTGGGCTGCCCTGGGCTGGGCTTCGACTCAGGGGTGGAACACTCAGCATTGTCTCCGGGTGACTTCAGCCAATGAACTCA
TAAAGCCAAGGAGTGGGGGCGGGGACTGGGCTGAGGGAGAACAGGGTCTCTGGAACCGTGGAAGCCAGGCTGGTCTGGCAGGAGCACCCA
CTCCCCGCCCGCTGGAAGGAAGCCTGTCCCCAGGACAGGACTCTGGTGGCCCTGCTGCTGCTGCATTGGTTTCCCTGTCACAAGTCAAGC
TGGAGGGGAGGCGGCCCACGTCCAGCCTGTTTGCATCACCTGGCTGTGGGGACTGACCCTGCATTGGTCTTTGTCCCACTAGGGTGGGTT
TCCTGCAGCTTCTTTGGCTATGAAGAAAAGCACCCCCAGGGCTGTGTCCTTGGTGTGGTAGGACAGTTGTCCCTGACAGTCACCCAGACA
GGCCTGCATAGCACCCCAGTTACACAGACAGATTTCCACAGCACTGCCTTACCATTGAGCACATAGTTAAATCTAGGGAAATCAGTGCCC
AGACATCAAAGCTAGAAATGAAACATGGTCAGCAGGAGCCTTGCATGGGCTTCTCTTTTGCTGGAGCAAGCCAAAATAATAGGAACGGTT
TTACATTCCTAGTGCCAGGACCCATCTCGGGTCGACAAAATCTGAAGACAAGTTAAGGGAACAGGCAGCTGTTTGAATAGATCAATTGGA
TAGTCTAAGGCAGCTCTCTGGACCAAGCTGTAAAGGAGATACAATCGAAATAATCACTCCGGTACCACAGTAGACAGGCCTTGAAGGCAC
TGGGCCCCTTTTAATCGGACTTAGCAAGCATTTTTTTTGCCTCTGACCTTCTCCTTGGAACAAAATTAGTTACCAGTAGACTTAGGTGAT
TGCTGTACTGCATGTAGGCACATAACCCCAACCTATATAAACAGTAAGAAAATTGTAGCACTTTGAGTTGGTCTGCTGGAATTATCTCCA

>9353_9353_5_BCL2L13-DGCR14_BCL2L13_chr22_18166087_ENST00000493680_DGCR14_chr22_19124945_ENST00000252137_length(amino acids)=358AA_BP=
MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIM
ELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHS

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Fusion Gene PPI Analysis for BCL2L13-DGCR14


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BCL2L13-DGCR14


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BCL2L13-DGCR14


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource