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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:TRA2A-AGFG2 (FusionGDB2 ID:93571) |
Fusion Gene Summary for TRA2A-AGFG2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TRA2A-AGFG2 | Fusion gene ID: 93571 | Hgene | Tgene | Gene symbol | TRA2A | AGFG2 | Gene ID | 29896 | 3268 |
| Gene name | transformer 2 alpha homolog | ArfGAP with FG repeats 2 | |
| Synonyms | AWMS1|HSU53209 | HRBL|RABR | |
| Cytomap | 7p15.3 | 7q22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | transformer-2 protein homolog alphaTRA-2 alphaTRA2-alphaTra2alphahtra-2 alphaputative MAPK activating protein PM24transformer-2 alphatransformer-2 protein homolog A | arf-GAP domain and FG repeat-containing protein 2HIV-1 Rev-binding protein-like proteinRev/Rex activation domain binding protein-relatedarf-GAP domain and FG repeats-containing protein 2nucleoporinrev/Rex activation domain-binding protein related | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | O95081 | |
| Ensembl transtripts involved in fusion gene | ENST00000297071, ENST00000392502, ENST00000474586, ENST00000538367, | ENST00000474713, ENST00000262935, ENST00000300176, | |
| Fusion gene scores | * DoF score | 20 X 14 X 9=2520 | 3 X 3 X 3=27 |
| # samples | 24 | 3 | |
| ** MAII score | log2(24/2520*10)=-3.39231742277876 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: TRA2A [Title/Abstract] AND AGFG2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | TRA2A(23547038)-AGFG2(100146444), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | TRA2A-AGFG2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. TRA2A-AGFG2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | TRA2A | GO:0000398 | mRNA splicing, via spliceosome | 9546399 |
| Fusion gene breakpoints across TRA2A (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across AGFG2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | ESCA | TCGA-IG-A3YC | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + |
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Fusion Gene ORF analysis for TRA2A-AGFG2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000297071 | ENST00000474713 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + |
| 5CDS-intron | ENST00000392502 | ENST00000474713 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + |
| 5CDS-intron | ENST00000474586 | ENST00000474713 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + |
| 5CDS-intron | ENST00000538367 | ENST00000474713 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + |
| Frame-shift | ENST00000392502 | ENST00000262935 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + |
| Frame-shift | ENST00000392502 | ENST00000300176 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + |
| Frame-shift | ENST00000538367 | ENST00000262935 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + |
| Frame-shift | ENST00000538367 | ENST00000300176 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + |
| In-frame | ENST00000297071 | ENST00000262935 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + |
| In-frame | ENST00000297071 | ENST00000300176 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + |
| In-frame | ENST00000474586 | ENST00000262935 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + |
| In-frame | ENST00000474586 | ENST00000300176 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000297071 | TRA2A | chr7 | 23547038 | - | ENST00000300176 | AGFG2 | chr7 | 100146444 | + | 5311 | 858 | 217 | 2082 | 621 |
| ENST00000297071 | TRA2A | chr7 | 23547038 | - | ENST00000262935 | AGFG2 | chr7 | 100146444 | + | 2418 | 858 | 217 | 1104 | 295 |
| ENST00000474586 | TRA2A | chr7 | 23547038 | - | ENST00000300176 | AGFG2 | chr7 | 100146444 | + | 5321 | 868 | 875 | 2092 | 405 |
| ENST00000474586 | TRA2A | chr7 | 23547038 | - | ENST00000262935 | AGFG2 | chr7 | 100146444 | + | 2428 | 868 | 111 | 878 | 255 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000297071 | ENST00000300176 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + | 0.028693918 | 0.971306 |
| ENST00000297071 | ENST00000262935 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + | 0.1550213 | 0.8449787 |
| ENST00000474586 | ENST00000300176 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + | 0.036253545 | 0.9637464 |
| ENST00000474586 | ENST00000262935 | TRA2A | chr7 | 23547038 | - | AGFG2 | chr7 | 100146444 | + | 0.30635262 | 0.6936474 |
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Fusion Genomic Features for TRA2A-AGFG2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| TRA2A | chr7 | 23547039 | - | AGFG2 | chr7 | 100146444 | + | 0.000656665 | 0.99934334 |
| TRA2A | chr7 | 23547039 | - | AGFG2 | chr7 | 100146444 | + | 0.000656665 | 0.99934334 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for TRA2A-AGFG2 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:23547038/chr7:100146444) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | AGFG2 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TRA2A | chr7:23547038 | chr7:100146444 | ENST00000297071 | - | 5 | 8 | 30_112 | 213 | 283.0 | Compositional bias | Note=Arg/Ser-rich (RS1 domain) |
| Hgene | TRA2A | chr7:23547038 | chr7:100146444 | ENST00000297071 | - | 5 | 8 | 119_197 | 213 | 283.0 | Domain | RRM |
| Tgene | AGFG2 | chr7:23547038 | chr7:100146444 | ENST00000262935 | 0 | 10 | 367_427 | 73 | 279.0 | Compositional bias | Note=Pro-rich | |
| Tgene | AGFG2 | chr7:23547038 | chr7:100146444 | ENST00000300176 | 0 | 12 | 367_427 | 73 | 482.0 | Compositional bias | Note=Pro-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TRA2A | chr7:23547038 | chr7:100146444 | ENST00000297071 | - | 5 | 8 | 226_282 | 213 | 283.0 | Compositional bias | Note=Arg/Ser-rich (RS2 domain) |
| Hgene | TRA2A | chr7:23547038 | chr7:100146444 | ENST00000297071 | - | 5 | 8 | 198_225 | 213 | 283.0 | Region | Note=Linker |
| Tgene | AGFG2 | chr7:23547038 | chr7:100146444 | ENST00000262935 | 0 | 10 | 27_153 | 73 | 279.0 | Domain | Arf-GAP | |
| Tgene | AGFG2 | chr7:23547038 | chr7:100146444 | ENST00000300176 | 0 | 12 | 27_153 | 73 | 482.0 | Domain | Arf-GAP | |
| Tgene | AGFG2 | chr7:23547038 | chr7:100146444 | ENST00000262935 | 0 | 10 | 47_70 | 73 | 279.0 | Zinc finger | C4-type | |
| Tgene | AGFG2 | chr7:23547038 | chr7:100146444 | ENST00000300176 | 0 | 12 | 47_70 | 73 | 482.0 | Zinc finger | C4-type |
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Fusion Gene Sequence for TRA2A-AGFG2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >93571_93571_1_TRA2A-AGFG2_TRA2A_chr7_23547038_ENST00000297071_AGFG2_chr7_100146444_ENST00000262935_length(transcript)=2418nt_BP=858nt GCCCGCCCCCTTTACGTCGTGCTCTGAGGAGGCCAGGAGATTTCTGGCGGCGCCGGCGCCATTTTGCTGGAGCCTGCGACCGAGTGGGAG TGGAGTGGAGCGGCTGTGGTTGCCGACTCTTTCCTCTTCCCCACGGTCCAGTCAGCGGGTTAATTAGGCCATCGGCCCTCGAGCCGAGAC TTGTCTCTTATTTAGTTCTGGGGAGCGCCTCGTCGACATGAGTGATGTGGAGGAAAACAACTTCGAGGGCAGAGAGTCTCGCTCTCAGTC AAAATCTCCAACGGGAACTCCTGCTCGTGTAAAATCGGAGAGCAGGTCAGGATCTCGTAGTCCATCAAGGGTTTCCAAACACTCTGAATC CCATTCTCGATCAAGATCAAAATCCAGGTCGAGGTCAAGGAGACATTCTCATAGACGTTACACTCGATCCAGATCCCACTCTCACTCTCA TAGGAGACGATCTCGAAGTAGATCATATACACCAGAATACCGGCGGCGAAGGAGCCGAAGCCATTCTCCAATGTCTAACCGGAGAAGACA TACTGGCAGCAGGGCAAATCCAGATCCCAACACTTGCCTTGGAGTGTTTGGCCTCAGTTTGTACACAACAGAGAGGGATCTTCGTGAAGT ATTTTCTCGATATGGACCATTGAGTGGTGTCAATGTGGTTTATGATCAGCGAACTGGGCGATCTCGAGGATTTGCTTTTGTGTATTTTGA GAGAATAGATGACTCAAAGGAGGCTATGGAAAGGGCAAATGGAATGGAGCTGGATGGTAGAAGAATTCGGGTGGATTATTCTATAACCAA GAGAGCGCACACACCAACACCAGGCATCTACATGGGCAGACCAACTCAGAGAGGGCTGAACCCCCCTCATCGTGTCAAGTCAATCTCCAT GACAACTTTCACTGAGCCTGAAGTAGTATTCCTGCAATCCCGTGGAAATGAGGTTTGCCGGAAGATTTGGTTGGGTCTGTTTGATGCTCG GACATCTTTAGTACCAGATTCCAGGGATCCTCAGAAAGTGAAGGAGTTTCTCCAGGAAAAATATGAGAAGAAGAGATGGCCAGACACCTT CCCAAGGAGGCTTTGCCAACTTTGATGCCTTTAGCAGTGGCCCCAGCTCTTCTGTGTTTGGAAGCCTCCCTCCAGCTGGTCAAGCCTCGT TCCAGGCCCAGCCAACTCCTGCAGGGAGCAGCCAGGGGACTCCATTTGGTGCCACTCCCCTGGCACCCGCCAGTCAGCCAAACAGCCTCG CAGACGTGGGCAGCTTCCTGGGACCCGGGGTGCCCGCTGCAGGTGTTCCTAGCAGCCTCTTCGGGATGGCTGGCCAGGTCCCCCCGCTCC AGTCTGTCACGATGGGCGGCGGCGGCGGCAGCAGCACAGGGCTGGCCTTTGGAGCCTTCACTAACCCTTTCACAGCTCCCGCCGCCCAGT CCCCGCTGCCTTCCACCAACCCGTTCCAGCCCAATGGCTTGGCGCCAGGGCCCGGCTTTGGGATGAGCAGTGCTGGGCCTGGCTTCCCCC AGGCAGTGCCACCCACTGGGGCCTTTGCCAGCTCCTTCCCAGCACCGCTGTTCCCCCCGCAGACCCCGCTTGTTCAGCAGCAGAATGGCT CTTCCTTCGGGGACTTAGGATCAGCCAAGTTGGGGCAGAGGCCACTGAGCCAGCCAGCTGGGATCTCCACCAACCCCTTCATGACTGGAC CCTCATCAAGCCCATTCGCCTCCAAACCTCCAACCACCAACCCCTTCTTGTAGCACTGTGTTTTTGGGGGGCCTCTTCCCTGCCTTCTGG GGCCCCTCTGCTCCCTAGAGCTCTGGTGACCACTTGCCTGTGGGCATTTCTATGGGCCTTGGGGATGGTGGAGGTGCTAATGCTTTGCTT GGGGCCTACAGGTGAAAGGTGGCTGCCCTCAGATTCCACAAAGCCTCTCTCCCCTCCCTCGTCCCACCCCCACCCAGGCAGGAAGCCCAG GAGGAGTGCGGGCAGGGCCTGACCTGGAGGAGTGATGGTTGAGGGGGAGGGATTTTTTTCAAATGATCAGTCCCCTGTGGAACAGCTCTT CCCTGGGCCTAGCTCGCCAGCGCTGTGCTCCTCATGGACGGGAGCGCAGTGGGGAAGGTAGGGGAAAGATGAGGCACAGTGTTGATGGGG CAGTGACCAGACAGTCCTGAGACCCAGAAGGCCCAGGTGGCCCAAGTGCTCTTGGTGGCCCAGCTTGGCCAGCACACACTTTCCTCCTGC AGCACCCCCTGCTGAAGGGGTCCCCCATTGTTTTGCTTCCCCAGCGCCCAGGATGAGCGGTTTACCATCGAGCTTACCCGGGCCCGGCTC >93571_93571_1_TRA2A-AGFG2_TRA2A_chr7_23547038_ENST00000297071_AGFG2_chr7_100146444_ENST00000262935_length(amino acids)=295AA_BP=214 MSDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHSHRRRSRSRSYTPE YRRRRSRSHSPMSNRRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERA NGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTQRGLNPPHRVKSISMTTFTEPEVVFLQSRGNEVCRKIWLGLFDARTSLVPDSRDPQK -------------------------------------------------------------- >93571_93571_2_TRA2A-AGFG2_TRA2A_chr7_23547038_ENST00000297071_AGFG2_chr7_100146444_ENST00000300176_length(transcript)=5311nt_BP=858nt GCCCGCCCCCTTTACGTCGTGCTCTGAGGAGGCCAGGAGATTTCTGGCGGCGCCGGCGCCATTTTGCTGGAGCCTGCGACCGAGTGGGAG TGGAGTGGAGCGGCTGTGGTTGCCGACTCTTTCCTCTTCCCCACGGTCCAGTCAGCGGGTTAATTAGGCCATCGGCCCTCGAGCCGAGAC TTGTCTCTTATTTAGTTCTGGGGAGCGCCTCGTCGACATGAGTGATGTGGAGGAAAACAACTTCGAGGGCAGAGAGTCTCGCTCTCAGTC AAAATCTCCAACGGGAACTCCTGCTCGTGTAAAATCGGAGAGCAGGTCAGGATCTCGTAGTCCATCAAGGGTTTCCAAACACTCTGAATC CCATTCTCGATCAAGATCAAAATCCAGGTCGAGGTCAAGGAGACATTCTCATAGACGTTACACTCGATCCAGATCCCACTCTCACTCTCA TAGGAGACGATCTCGAAGTAGATCATATACACCAGAATACCGGCGGCGAAGGAGCCGAAGCCATTCTCCAATGTCTAACCGGAGAAGACA TACTGGCAGCAGGGCAAATCCAGATCCCAACACTTGCCTTGGAGTGTTTGGCCTCAGTTTGTACACAACAGAGAGGGATCTTCGTGAAGT ATTTTCTCGATATGGACCATTGAGTGGTGTCAATGTGGTTTATGATCAGCGAACTGGGCGATCTCGAGGATTTGCTTTTGTGTATTTTGA GAGAATAGATGACTCAAAGGAGGCTATGGAAAGGGCAAATGGAATGGAGCTGGATGGTAGAAGAATTCGGGTGGATTATTCTATAACCAA GAGAGCGCACACACCAACACCAGGCATCTACATGGGCAGACCAACTCAGAGAGGGCTGAACCCCCCTCATCGTGTCAAGTCAATCTCCAT GACAACTTTCACTGAGCCTGAAGTAGTATTCCTGCAATCCCGTGGAAATGAGGTTTGCCGGAAGATTTGGTTGGGTCTGTTTGATGCTCG GACATCTTTAGTACCAGATTCCAGGGATCCTCAGAAAGTGAAGGAGTTTCTCCAGGAAAAATATGAGAAGAAGAGATGGTATGTCCCCCC AGACCAAGTCAAGGGGCCCACTTATACCAAAGGCAGTGCCTCCACCCCTGTGCAGGGCTCCATCCCAGAAGGGAAGCCCCTTCGGACACT TCTGGGTGATCCTGCACCGTCTCTCTCAGTTGCTGCCTCCACCTCGAGCCAGCCCGTCAGTCAGTCTCACGCTCGGACATCCCAGGCCCG GAGCACTCAGCCACCTCCCCACTCCTCTGTCAAAAAAGCCAGTACTGACCTGCTGGCTGACATCGGTGGAGACCCCTTTGCTGCACCCCA GATGGCACCAGCTTTTGCTGCATTCCCTGCCTTTGGGGGCCAGACACCTTCCCAAGGAGGCTTTGCCAACTTTGATGCCTTTAGCAGTGG CCCCAGCTCTTCTGTGTTTGGAAGCCTCCCTCCAGCTGGTCAAGCCTCGTTCCAGGCCCAGCCAACTCCTGCAGGGAGCAGCCAGGGGAC TCCATTTGGTGCCACTCCCCTGGCACCCGCCAGTCAGCCAAACAGCCTCGCAGACGTGGGCAGCTTCCTGGGACCCGGGGTGCCCGCTGC AGGTGTTCCTAGCAGCCTCTTCGGGATGGCTGGCCAGGTCCCCCCGCTCCAGTCTGTCACGATGGGCGGCGGCGGCGGCAGCAGCACAGG GCTGGCCTTTGGAGCCTTCACTAACCCTTTCACAGCTCCCGCCGCCCAGTCCCCGCTGCCTTCCACCAACCCGTTCCAGCCCAATGGCTT GGCGCCAGGGCCCGGCTTTGGGATGAGCAGTGCTGGGCCTGGCTTCCCCCAGGCAGTGCCACCCACTGGGGCCTTTGCCAGCTCCTTCCC AGCACCGCTGTTCCCCCCGCAGACCCCGCTTGTTCAGCAGCAGAATGGCTCTTCCTTCGGGGACTTAGGATCAGCCAAGTTGGGGCAGAG GCCACTGAGCCAGCCAGCTGGGATCTCCACCAACCCCTTCATGACTGGACCCTCATCAAGCCCATTCGCCTCCAAACCTCCAACCACCAA CCCCTTCTTGTAGCACTGTGTTTTTGGGGGGCCTCTTCCCTGCCTTCTGGGGCCCCTCTGCTCCCTAGAGCTCTGGTGACCACTTGCCTG TGGGCATTTCTATGGGCCTTGGGGATGGTGGAGGTGCTAATGCTTTGCTTGGGGCCTACAGGTGAAAGGTGGCTGCCCTCAGATTCCACA AAGCCTCTCTCCCCTCCCTCGTCCCACCCCCACCCAGGCAGGAAGCCCAGGAGGAGTGCGGGCAGGGCCTGACCTGGAGGAGTGATGGTT GAGGGGGAGGGATTTTTTTCAAATGATCAGTCCCCTGTGGAACAGCTCTTCCCTGGGCCTAGCTCGCCAGCGCTGTGCTCCTCATGGACG GGAGCGCAGTGGGGAAGGTAGGGGAAAGATGAGGCACAGTGTTGATGGGGCAGTGACCAGACAGTCCTGAGACCCAGAAGGCCCAGGTGG CCCAAGTGCTCTTGGTGGCCCAGCTTGGCCAGCACACACTTTCCTCCTGCAGCACCCCCTGCTGAAGGGGTCCCCCATTGTTTTGCTTCC CCAGCGCCCAGGATGAGCGGTTTACCATCGAGCTTACCCGGGCCCGGCTCCTGTCAAGCACTTTAGTTAGCTGTTGGTGTCATGTTTGGA TACCAGTGTTTTATATTTATACATAGAGAGGATTTTCTAATATAGCCTATTATATATAAATAGATCTATCTATATGCACATACATACATA TATACACACACCCAGCCGATCTCCCGCTCCCAGACTGCTCTCGTATGTGGGGAATGGGATGAATCCCCATCTGTGCCTCGACCATCAAAG CCGGAGCTCCAGGGCTGGAGGGGGGGCAGCCATGTGTCCTGACCCCCACCATCCCCAGAGCCTGGGTTTTCCAGGGAAAGGCTTTGTGCA ATTGCCTGGTCTTTTTTTTTTTTTTTTTTTCTCCATGTGCCTCCCTGTCCCCAAATCTCTGCACCAAAGCTCATTGCAGGCAATGTTGGA AAAGAACTGCATTTGAACGAAAGAGAAAACGGCGCCTGTGGTTTTGCTTCAGGCCACTTTGAGGGGTTGCAGGTCAGTCAACATGACTGA TCCTTGACCTGGCTCTGCTGGGCTGGACTGCCTGGGCCAGTGATAATGCTGCCATTGGCCAGAGACAGGGCAGAGCCCGTCCCTGTCTGA ACAAGAGTCCCGCATTAGCAATGAGAAGAAGCGTGGCGGGAGAGGAGCCACCACTGCCGGGGACTGGAGTTTGTTGGATGTGAGGGGAAT GCCCACTGGGGCCAGGGTGGGCAAAGGAGGTTGGTGCCAATGTGGTGCTGGAAGTAGACCCCTCCTGGGTCTGGAACATTCTCTGCCCCA GGCTCTTTCCACCTGGGGATGTTGTGACAACATCCAGCTGTGGTGTCTGGGCTATTTGTGTGGTGACAAGACAGACCTGGTCAGGGGGTG GGTGGCAAACACCTCACCTGGCTGGGCAGAGGCCACCTTGCTGTTTGGCCCAAGGCCAGGTGAGGCCCCTCCCTTTCCACCATTGCCCTG GCCCCGTGGCCATTCATTCTTGGGGTTTGTCTGAGTCTTCCACAGAGAGCAGCAAAGAGATATGGGAGTTGGGTGATCAGTGTATTTACT TTGCAGATTTTTCTGGAAATAACCTCTAGCTGCTGCTATTTGCAAGGCTGGGATTGGCCTCCCTGTCTTTTCCAACAATCAGGACCCCAT CCTGTCTGTTCCTGTTCTTCTCCCAGCCTCTGCCCTCCTTCTGTCTCCTGGGTGGTCTCCCGCTTCGCTCCTGGCCTTTGCATGTTCCAT CTCTTCTCTTTCTCCCCTCTTCGCCACCCTAGATTATCTCTGTGTCCCTCTACCTAATTCTCTTACCAGTTCTTTCCTTTCTGCTTAGAG CCGGAGGGAGGGAAGCTGGAATCTGTTATGGTGTATTAGGGGGAGGAGCCTTTCTGTTATTTCCCCCCAGCTTCCATCACCCTTCCCTTA ATGCCAGGAGCGCCGAGGTTTGGAACTGAGGCTAAACCGAAGGGCTTTCTCCTGCTTCTGTCACCCTGTGCTGTCTCCCGGCATCTCCTC ACTATCTGGGTCCAGGCCCGGGTCCTCCCTGCAGACTCCCTCCCCTCCAGCCCACAAGGACTCCAGCCTGCTGGCTGGTGAGAGCTGGAT GAGCAGTAAGAAGTTAACGCCAGGTCAGCCTCGGGCCCCAGGGTTCCCTGGGCACAGGCTGACACTAGGAGCTGCTCTCCTTGGCCGGGG ACAGCTCCAGCAGCTCAGGCTCCAGCCCTCCAGTGAGCCGCCTCTCCTGGAGAGTAGCAAAGAATGGAGAAAGGCCTGGCTTGAGAGGAA ATGGAGAAAACATTGCCTGGTAGCTGCAGATTCAAACCCACCACACACACCACGGGGCTAGAGTGACTCACCTGGGCTCACACCAACTTC TGGCCAATGCAGGGACCATGCTCTGCAGACAGCAGTCCTCTAGCATGGCCCCAGCATTCAGCCAGTCGGTCACCTGTGGGCCATCCCCAT GTGTGAGGAAGCAGGAGTCAGCCACCAAGTGTCTCCACATCGGAGCTTGCGGGTCAGACCTGTGGGCCAGGGGATGGGAGCAGGGCTGAG GGTAGGGGCTGAATGTGTGGCTCTGTCCCTGTGTTGCCTTCCACAGAGGAGCAAGGCCTCAGGCTGAGGAAGGAGGGGCACGCTGGAACA GCCTAGTCTCCTCCCCGTGGATTCCCCCAAACCCATAACATTCTTCCATAGGGGCTGAGAACGCAGTGCCCCGTCCCTGACAGGGATGAA AAGTGAACCCCTCAGGTCAGGAGAGGCAGAGTTGAGGTTCTGCCACTTCCTGTCCCTGGGGAGCCACTCAAGTTACCAGGGCTACCGGCT GAAATAAATCTTTTCCGGGTAGGGTCAAGGGCAGTGTGTTGCCAAGGCAACTGATGTAGGCCAGTTGCGTGACTCCAGGTTTGTCCTGGT ACTCAGTGGGTCCAATCACCTGGCATTGATCACCTGGCATTGATCAGCACCCACCCCACCCCTGAGGCTTGCCCAGCCCCCAGGCCCTCA GATCCCTGCTCTTCCTGCCTTTCCTGCCCATGTGTCACCCAGCACCCAAGGTTCAGTGACACAGGGTGGTTTGGAGCTGGTCACTGTCAT AGCAGCTGTGATTTCACAAGGAAGGGTGCTGCAGGGGGACCTGGTTGATGGGGAGTGGGAAGGGGAAGGAATAAAGAGATCTTCCTCAGG >93571_93571_2_TRA2A-AGFG2_TRA2A_chr7_23547038_ENST00000297071_AGFG2_chr7_100146444_ENST00000300176_length(amino acids)=621AA_BP=214 MSDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHSHRRRSRSRSYTPE YRRRRSRSHSPMSNRRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERA NGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTQRGLNPPHRVKSISMTTFTEPEVVFLQSRGNEVCRKIWLGLFDARTSLVPDSRDPQK VKEFLQEKYEKKRWYVPPDQVKGPTYTKGSASTPVQGSIPEGKPLRTLLGDPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKK ASTDLLADIGGDPFAAPQMAPAFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPFGATPLAPASQ PNSLADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSSTGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAG -------------------------------------------------------------- >93571_93571_3_TRA2A-AGFG2_TRA2A_chr7_23547038_ENST00000474586_AGFG2_chr7_100146444_ENST00000262935_length(transcript)=2428nt_BP=868nt CTGGAGCCATCGCGATTGATTCCTCCCATCCCAAGATGGCTTCTGGGTTCCACTCCTTCCCCAAACACCACGGATAACACCCCTCCCCCT TTTTTGGAGGCTGACTGATACCTGGACTTCTGGGTCCTCTTCCCTCCCCGCCCCCGCATTGCTTCCTCCCTTCTCCCCACCCCTGAGGCT TCCTTATGTCTGCTCCGAGGTGTGGGTCCCCGTCGCGGTTGGGCGGGAGGAGGCGGCAGGGAGCTCCCCTCCGTCCGGATAGTGGAGTCT CGCTCTCAGTCAAAATCTCCAACGGGAACTCCTGCTCGTGTAAAATCGGAGAGCAGGTCAGGATCTCGTAGTCCATCAAGGGTTTCCAAA CACTCTGAATCCCATTCTCGATCAAGATCAAAATCCAGGTCGAGGTCAAGGAGACATTCTCATAGACGTTACACTCGATCCAGATCCCAC TCTCACTCTCATAGGAGACGATCTCGAAGTAGATCATATACACCAGAATACCGGCGGCGAAGGAGCCGAAGCCATTCTCCAATGTCTAAC CGGAGAAGACATACTGGCAGCAGGGCAAATCCAGATCCCAACACTTGCCTTGGAGTGTTTGGCCTCAGTTTGTACACAACAGAGAGGGAT CTTCGTGAAGTATTTTCTCGATATGGACCATTGAGTGGTGTCAATGTGGTTTATGATCAGCGAACTGGGCGATCTCGAGGATTTGCTTTT GTGTATTTTGAGAGAATAGATGACTCAAAGGAGGCTATGGAAAGGGCAAATGGAATGGAGCTGGATGGTAGAAGAATTCGGGTGGATTAT TCTATAACCAAGAGAGCGCACACACCAACACCAGGCATCTACATGGGCAGACCAACTCGAGAGGGCTGAACCCCCCTCATCGTGTCAAGT CAATCTCCATGACAACTTTCACTGAGCCTGAAGTAGTATTCCTGCAATCCCGTGGAAATGAGGTTTGCCGGAAGATTTGGTTGGGTCTGT TTGATGCTCGGACATCTTTAGTACCAGATTCCAGGGATCCTCAGAAAGTGAAGGAGTTTCTCCAGGAAAAATATGAGAAGAAGAGATGGC CAGACACCTTCCCAAGGAGGCTTTGCCAACTTTGATGCCTTTAGCAGTGGCCCCAGCTCTTCTGTGTTTGGAAGCCTCCCTCCAGCTGGT CAAGCCTCGTTCCAGGCCCAGCCAACTCCTGCAGGGAGCAGCCAGGGGACTCCATTTGGTGCCACTCCCCTGGCACCCGCCAGTCAGCCA AACAGCCTCGCAGACGTGGGCAGCTTCCTGGGACCCGGGGTGCCCGCTGCAGGTGTTCCTAGCAGCCTCTTCGGGATGGCTGGCCAGGTC CCCCCGCTCCAGTCTGTCACGATGGGCGGCGGCGGCGGCAGCAGCACAGGGCTGGCCTTTGGAGCCTTCACTAACCCTTTCACAGCTCCC GCCGCCCAGTCCCCGCTGCCTTCCACCAACCCGTTCCAGCCCAATGGCTTGGCGCCAGGGCCCGGCTTTGGGATGAGCAGTGCTGGGCCT GGCTTCCCCCAGGCAGTGCCACCCACTGGGGCCTTTGCCAGCTCCTTCCCAGCACCGCTGTTCCCCCCGCAGACCCCGCTTGTTCAGCAG CAGAATGGCTCTTCCTTCGGGGACTTAGGATCAGCCAAGTTGGGGCAGAGGCCACTGAGCCAGCCAGCTGGGATCTCCACCAACCCCTTC ATGACTGGACCCTCATCAAGCCCATTCGCCTCCAAACCTCCAACCACCAACCCCTTCTTGTAGCACTGTGTTTTTGGGGGGCCTCTTCCC TGCCTTCTGGGGCCCCTCTGCTCCCTAGAGCTCTGGTGACCACTTGCCTGTGGGCATTTCTATGGGCCTTGGGGATGGTGGAGGTGCTAA TGCTTTGCTTGGGGCCTACAGGTGAAAGGTGGCTGCCCTCAGATTCCACAAAGCCTCTCTCCCCTCCCTCGTCCCACCCCCACCCAGGCA GGAAGCCCAGGAGGAGTGCGGGCAGGGCCTGACCTGGAGGAGTGATGGTTGAGGGGGAGGGATTTTTTTCAAATGATCAGTCCCCTGTGG AACAGCTCTTCCCTGGGCCTAGCTCGCCAGCGCTGTGCTCCTCATGGACGGGAGCGCAGTGGGGAAGGTAGGGGAAAGATGAGGCACAGT GTTGATGGGGCAGTGACCAGACAGTCCTGAGACCCAGAAGGCCCAGGTGGCCCAAGTGCTCTTGGTGGCCCAGCTTGGCCAGCACACACT TTCCTCCTGCAGCACCCCCTGCTGAAGGGGTCCCCCATTGTTTTGCTTCCCCAGCGCCCAGGATGAGCGGTTTACCATCGAGCTTACCCG >93571_93571_3_TRA2A-AGFG2_TRA2A_chr7_23547038_ENST00000474586_AGFG2_chr7_100146444_ENST00000262935_length(amino acids)=255AA_BP= MDFWVLFPPRPRIASSLLPTPEASLCLLRGVGPRRGWAGGGGRELPSVRIVESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSR SRSKSRSRSRRHSHRRYTRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSR -------------------------------------------------------------- >93571_93571_4_TRA2A-AGFG2_TRA2A_chr7_23547038_ENST00000474586_AGFG2_chr7_100146444_ENST00000300176_length(transcript)=5321nt_BP=868nt CTGGAGCCATCGCGATTGATTCCTCCCATCCCAAGATGGCTTCTGGGTTCCACTCCTTCCCCAAACACCACGGATAACACCCCTCCCCCT TTTTTGGAGGCTGACTGATACCTGGACTTCTGGGTCCTCTTCCCTCCCCGCCCCCGCATTGCTTCCTCCCTTCTCCCCACCCCTGAGGCT TCCTTATGTCTGCTCCGAGGTGTGGGTCCCCGTCGCGGTTGGGCGGGAGGAGGCGGCAGGGAGCTCCCCTCCGTCCGGATAGTGGAGTCT CGCTCTCAGTCAAAATCTCCAACGGGAACTCCTGCTCGTGTAAAATCGGAGAGCAGGTCAGGATCTCGTAGTCCATCAAGGGTTTCCAAA CACTCTGAATCCCATTCTCGATCAAGATCAAAATCCAGGTCGAGGTCAAGGAGACATTCTCATAGACGTTACACTCGATCCAGATCCCAC TCTCACTCTCATAGGAGACGATCTCGAAGTAGATCATATACACCAGAATACCGGCGGCGAAGGAGCCGAAGCCATTCTCCAATGTCTAAC CGGAGAAGACATACTGGCAGCAGGGCAAATCCAGATCCCAACACTTGCCTTGGAGTGTTTGGCCTCAGTTTGTACACAACAGAGAGGGAT CTTCGTGAAGTATTTTCTCGATATGGACCATTGAGTGGTGTCAATGTGGTTTATGATCAGCGAACTGGGCGATCTCGAGGATTTGCTTTT GTGTATTTTGAGAGAATAGATGACTCAAAGGAGGCTATGGAAAGGGCAAATGGAATGGAGCTGGATGGTAGAAGAATTCGGGTGGATTAT TCTATAACCAAGAGAGCGCACACACCAACACCAGGCATCTACATGGGCAGACCAACTCGAGAGGGCTGAACCCCCCTCATCGTGTCAAGT CAATCTCCATGACAACTTTCACTGAGCCTGAAGTAGTATTCCTGCAATCCCGTGGAAATGAGGTTTGCCGGAAGATTTGGTTGGGTCTGT TTGATGCTCGGACATCTTTAGTACCAGATTCCAGGGATCCTCAGAAAGTGAAGGAGTTTCTCCAGGAAAAATATGAGAAGAAGAGATGGT ATGTCCCCCCAGACCAAGTCAAGGGGCCCACTTATACCAAAGGCAGTGCCTCCACCCCTGTGCAGGGCTCCATCCCAGAAGGGAAGCCCC TTCGGACACTTCTGGGTGATCCTGCACCGTCTCTCTCAGTTGCTGCCTCCACCTCGAGCCAGCCCGTCAGTCAGTCTCACGCTCGGACAT CCCAGGCCCGGAGCACTCAGCCACCTCCCCACTCCTCTGTCAAAAAAGCCAGTACTGACCTGCTGGCTGACATCGGTGGAGACCCCTTTG CTGCACCCCAGATGGCACCAGCTTTTGCTGCATTCCCTGCCTTTGGGGGCCAGACACCTTCCCAAGGAGGCTTTGCCAACTTTGATGCCT TTAGCAGTGGCCCCAGCTCTTCTGTGTTTGGAAGCCTCCCTCCAGCTGGTCAAGCCTCGTTCCAGGCCCAGCCAACTCCTGCAGGGAGCA GCCAGGGGACTCCATTTGGTGCCACTCCCCTGGCACCCGCCAGTCAGCCAAACAGCCTCGCAGACGTGGGCAGCTTCCTGGGACCCGGGG TGCCCGCTGCAGGTGTTCCTAGCAGCCTCTTCGGGATGGCTGGCCAGGTCCCCCCGCTCCAGTCTGTCACGATGGGCGGCGGCGGCGGCA GCAGCACAGGGCTGGCCTTTGGAGCCTTCACTAACCCTTTCACAGCTCCCGCCGCCCAGTCCCCGCTGCCTTCCACCAACCCGTTCCAGC CCAATGGCTTGGCGCCAGGGCCCGGCTTTGGGATGAGCAGTGCTGGGCCTGGCTTCCCCCAGGCAGTGCCACCCACTGGGGCCTTTGCCA GCTCCTTCCCAGCACCGCTGTTCCCCCCGCAGACCCCGCTTGTTCAGCAGCAGAATGGCTCTTCCTTCGGGGACTTAGGATCAGCCAAGT TGGGGCAGAGGCCACTGAGCCAGCCAGCTGGGATCTCCACCAACCCCTTCATGACTGGACCCTCATCAAGCCCATTCGCCTCCAAACCTC CAACCACCAACCCCTTCTTGTAGCACTGTGTTTTTGGGGGGCCTCTTCCCTGCCTTCTGGGGCCCCTCTGCTCCCTAGAGCTCTGGTGAC CACTTGCCTGTGGGCATTTCTATGGGCCTTGGGGATGGTGGAGGTGCTAATGCTTTGCTTGGGGCCTACAGGTGAAAGGTGGCTGCCCTC AGATTCCACAAAGCCTCTCTCCCCTCCCTCGTCCCACCCCCACCCAGGCAGGAAGCCCAGGAGGAGTGCGGGCAGGGCCTGACCTGGAGG AGTGATGGTTGAGGGGGAGGGATTTTTTTCAAATGATCAGTCCCCTGTGGAACAGCTCTTCCCTGGGCCTAGCTCGCCAGCGCTGTGCTC CTCATGGACGGGAGCGCAGTGGGGAAGGTAGGGGAAAGATGAGGCACAGTGTTGATGGGGCAGTGACCAGACAGTCCTGAGACCCAGAAG GCCCAGGTGGCCCAAGTGCTCTTGGTGGCCCAGCTTGGCCAGCACACACTTTCCTCCTGCAGCACCCCCTGCTGAAGGGGTCCCCCATTG TTTTGCTTCCCCAGCGCCCAGGATGAGCGGTTTACCATCGAGCTTACCCGGGCCCGGCTCCTGTCAAGCACTTTAGTTAGCTGTTGGTGT CATGTTTGGATACCAGTGTTTTATATTTATACATAGAGAGGATTTTCTAATATAGCCTATTATATATAAATAGATCTATCTATATGCACA TACATACATATATACACACACCCAGCCGATCTCCCGCTCCCAGACTGCTCTCGTATGTGGGGAATGGGATGAATCCCCATCTGTGCCTCG ACCATCAAAGCCGGAGCTCCAGGGCTGGAGGGGGGGCAGCCATGTGTCCTGACCCCCACCATCCCCAGAGCCTGGGTTTTCCAGGGAAAG GCTTTGTGCAATTGCCTGGTCTTTTTTTTTTTTTTTTTTTCTCCATGTGCCTCCCTGTCCCCAAATCTCTGCACCAAAGCTCATTGCAGG CAATGTTGGAAAAGAACTGCATTTGAACGAAAGAGAAAACGGCGCCTGTGGTTTTGCTTCAGGCCACTTTGAGGGGTTGCAGGTCAGTCA ACATGACTGATCCTTGACCTGGCTCTGCTGGGCTGGACTGCCTGGGCCAGTGATAATGCTGCCATTGGCCAGAGACAGGGCAGAGCCCGT CCCTGTCTGAACAAGAGTCCCGCATTAGCAATGAGAAGAAGCGTGGCGGGAGAGGAGCCACCACTGCCGGGGACTGGAGTTTGTTGGATG TGAGGGGAATGCCCACTGGGGCCAGGGTGGGCAAAGGAGGTTGGTGCCAATGTGGTGCTGGAAGTAGACCCCTCCTGGGTCTGGAACATT CTCTGCCCCAGGCTCTTTCCACCTGGGGATGTTGTGACAACATCCAGCTGTGGTGTCTGGGCTATTTGTGTGGTGACAAGACAGACCTGG TCAGGGGGTGGGTGGCAAACACCTCACCTGGCTGGGCAGAGGCCACCTTGCTGTTTGGCCCAAGGCCAGGTGAGGCCCCTCCCTTTCCAC CATTGCCCTGGCCCCGTGGCCATTCATTCTTGGGGTTTGTCTGAGTCTTCCACAGAGAGCAGCAAAGAGATATGGGAGTTGGGTGATCAG TGTATTTACTTTGCAGATTTTTCTGGAAATAACCTCTAGCTGCTGCTATTTGCAAGGCTGGGATTGGCCTCCCTGTCTTTTCCAACAATC AGGACCCCATCCTGTCTGTTCCTGTTCTTCTCCCAGCCTCTGCCCTCCTTCTGTCTCCTGGGTGGTCTCCCGCTTCGCTCCTGGCCTTTG CATGTTCCATCTCTTCTCTTTCTCCCCTCTTCGCCACCCTAGATTATCTCTGTGTCCCTCTACCTAATTCTCTTACCAGTTCTTTCCTTT CTGCTTAGAGCCGGAGGGAGGGAAGCTGGAATCTGTTATGGTGTATTAGGGGGAGGAGCCTTTCTGTTATTTCCCCCCAGCTTCCATCAC CCTTCCCTTAATGCCAGGAGCGCCGAGGTTTGGAACTGAGGCTAAACCGAAGGGCTTTCTCCTGCTTCTGTCACCCTGTGCTGTCTCCCG GCATCTCCTCACTATCTGGGTCCAGGCCCGGGTCCTCCCTGCAGACTCCCTCCCCTCCAGCCCACAAGGACTCCAGCCTGCTGGCTGGTG AGAGCTGGATGAGCAGTAAGAAGTTAACGCCAGGTCAGCCTCGGGCCCCAGGGTTCCCTGGGCACAGGCTGACACTAGGAGCTGCTCTCC TTGGCCGGGGACAGCTCCAGCAGCTCAGGCTCCAGCCCTCCAGTGAGCCGCCTCTCCTGGAGAGTAGCAAAGAATGGAGAAAGGCCTGGC TTGAGAGGAAATGGAGAAAACATTGCCTGGTAGCTGCAGATTCAAACCCACCACACACACCACGGGGCTAGAGTGACTCACCTGGGCTCA CACCAACTTCTGGCCAATGCAGGGACCATGCTCTGCAGACAGCAGTCCTCTAGCATGGCCCCAGCATTCAGCCAGTCGGTCACCTGTGGG CCATCCCCATGTGTGAGGAAGCAGGAGTCAGCCACCAAGTGTCTCCACATCGGAGCTTGCGGGTCAGACCTGTGGGCCAGGGGATGGGAG CAGGGCTGAGGGTAGGGGCTGAATGTGTGGCTCTGTCCCTGTGTTGCCTTCCACAGAGGAGCAAGGCCTCAGGCTGAGGAAGGAGGGGCA CGCTGGAACAGCCTAGTCTCCTCCCCGTGGATTCCCCCAAACCCATAACATTCTTCCATAGGGGCTGAGAACGCAGTGCCCCGTCCCTGA CAGGGATGAAAAGTGAACCCCTCAGGTCAGGAGAGGCAGAGTTGAGGTTCTGCCACTTCCTGTCCCTGGGGAGCCACTCAAGTTACCAGG GCTACCGGCTGAAATAAATCTTTTCCGGGTAGGGTCAAGGGCAGTGTGTTGCCAAGGCAACTGATGTAGGCCAGTTGCGTGACTCCAGGT TTGTCCTGGTACTCAGTGGGTCCAATCACCTGGCATTGATCACCTGGCATTGATCAGCACCCACCCCACCCCTGAGGCTTGCCCAGCCCC CAGGCCCTCAGATCCCTGCTCTTCCTGCCTTTCCTGCCCATGTGTCACCCAGCACCCAAGGTTCAGTGACACAGGGTGGTTTGGAGCTGG TCACTGTCATAGCAGCTGTGATTTCACAAGGAAGGGTGCTGCAGGGGGACCTGGTTGATGGGGAGTGGGAAGGGGAAGGAATAAAGAGAT >93571_93571_4_TRA2A-AGFG2_TRA2A_chr7_23547038_ENST00000474586_AGFG2_chr7_100146444_ENST00000300176_length(amino acids)=405AA_BP= MNPPHRVKSISMTTFTEPEVVFLQSRGNEVCRKIWLGLFDARTSLVPDSRDPQKVKEFLQEKYEKKRWYVPPDQVKGPTYTKGSASTPVQ GSIPEGKPLRTLLGDPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAPAFAAFPAFGGQTPSQ GGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPFGATPLAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQS VTMGGGGGSSTGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFASSFPAPLFPPQTPLVQQQNGSS -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for TRA2A-AGFG2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for TRA2A-AGFG2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for TRA2A-AGFG2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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