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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TRA2A-AQP1 (FusionGDB2 ID:93572)

Fusion Gene Summary for TRA2A-AQP1

check button Fusion gene summary
Fusion gene informationFusion gene name: TRA2A-AQP1
Fusion gene ID: 93572
HgeneTgene
Gene symbol

TRA2A

AQP1

Gene ID

29896

84182

Gene nametransformer 2 alpha homologMINDY lysine 48 deubiquitinase 4
SynonymsAWMS1|HSU53209AQP-1|AQP1|C7orf67|CHIP28|FAM188B
Cytomap

7p15.3

7p14.3

Type of geneprotein-codingprotein-coding
Descriptiontransformer-2 protein homolog alphaTRA-2 alphaTRA2-alphaTra2alphahtra-2 alphaputative MAPK activating protein PM24transformer-2 alphatransformer-2 protein homolog Aprobable ubiquitin carboxyl-terminal hydrolase MINDY-4Aquaporin-1Aquaporin-CHIPMINDY deubiquitinase 4Urine water channelWater channel protein for red blood cells and kidney proximal tubulefamily with sequence similarity 188 member Bprobable deubiqu
Modification date2020031320200313
UniProtAcc.

Q8NBQ7

Ensembl transtripts involved in fusion geneENST00000297071, ENST00000392502, 
ENST00000538367, ENST00000474586, 
ENST00000409611, ENST00000409899, 
ENST00000441328, ENST00000482461, 
ENST00000311813, ENST00000434909, 
ENST00000509504, 
Fusion gene scores* DoF score20 X 14 X 9=25205 X 7 X 3=105
# samples 246
** MAII scorelog2(24/2520*10)=-3.39231742277876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(6/105*10)=-0.807354922057604
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TRA2A [Title/Abstract] AND AQP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTRA2A(23571408)-AQP1(30961681), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTRA2A

GO:0000398

mRNA splicing, via spliceosome

9546399


check buttonFusion gene breakpoints across TRA2A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across AQP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CESCTCGA-EK-A2PM-01ATRA2Achr7

23571407

-AQP1chr7

30961680

+
ChimerDB4CESCTCGA-EK-A2PM-01ATRA2Achr7

23571408

-AQP1chr7

30961681

+


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Fusion Gene ORF analysis for TRA2A-AQP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000297071ENST00000409611TRA2Achr7

23571407

-AQP1chr7

30961680

+
5CDS-3UTRENST00000297071ENST00000409611TRA2Achr7

23571408

-AQP1chr7

30961681

+
5CDS-3UTRENST00000297071ENST00000409899TRA2Achr7

23571407

-AQP1chr7

30961680

+
5CDS-3UTRENST00000297071ENST00000409899TRA2Achr7

23571408

-AQP1chr7

30961681

+
5CDS-3UTRENST00000297071ENST00000441328TRA2Achr7

23571407

-AQP1chr7

30961680

+
5CDS-3UTRENST00000297071ENST00000441328TRA2Achr7

23571408

-AQP1chr7

30961681

+
5CDS-3UTRENST00000297071ENST00000482461TRA2Achr7

23571407

-AQP1chr7

30961680

+
5CDS-3UTRENST00000297071ENST00000482461TRA2Achr7

23571408

-AQP1chr7

30961681

+
5UTR-3CDSENST00000392502ENST00000311813TRA2Achr7

23571407

-AQP1chr7

30961680

+
5UTR-3CDSENST00000392502ENST00000311813TRA2Achr7

23571408

-AQP1chr7

30961681

+
5UTR-3CDSENST00000392502ENST00000434909TRA2Achr7

23571407

-AQP1chr7

30961680

+
5UTR-3CDSENST00000392502ENST00000434909TRA2Achr7

23571408

-AQP1chr7

30961681

+
5UTR-3CDSENST00000392502ENST00000509504TRA2Achr7

23571407

-AQP1chr7

30961680

+
5UTR-3CDSENST00000392502ENST00000509504TRA2Achr7

23571408

-AQP1chr7

30961681

+
5UTR-3CDSENST00000538367ENST00000311813TRA2Achr7

23571407

-AQP1chr7

30961680

+
5UTR-3CDSENST00000538367ENST00000311813TRA2Achr7

23571408

-AQP1chr7

30961681

+
5UTR-3CDSENST00000538367ENST00000434909TRA2Achr7

23571407

-AQP1chr7

30961680

+
5UTR-3CDSENST00000538367ENST00000434909TRA2Achr7

23571408

-AQP1chr7

30961681

+
5UTR-3CDSENST00000538367ENST00000509504TRA2Achr7

23571407

-AQP1chr7

30961680

+
5UTR-3CDSENST00000538367ENST00000509504TRA2Achr7

23571408

-AQP1chr7

30961681

+
5UTR-3UTRENST00000392502ENST00000409611TRA2Achr7

23571407

-AQP1chr7

30961680

+
5UTR-3UTRENST00000392502ENST00000409611TRA2Achr7

23571408

-AQP1chr7

30961681

+
5UTR-3UTRENST00000392502ENST00000409899TRA2Achr7

23571407

-AQP1chr7

30961680

+
5UTR-3UTRENST00000392502ENST00000409899TRA2Achr7

23571408

-AQP1chr7

30961681

+
5UTR-3UTRENST00000392502ENST00000441328TRA2Achr7

23571407

-AQP1chr7

30961680

+
5UTR-3UTRENST00000392502ENST00000441328TRA2Achr7

23571408

-AQP1chr7

30961681

+
5UTR-3UTRENST00000392502ENST00000482461TRA2Achr7

23571407

-AQP1chr7

30961680

+
5UTR-3UTRENST00000392502ENST00000482461TRA2Achr7

23571408

-AQP1chr7

30961681

+
5UTR-3UTRENST00000538367ENST00000409611TRA2Achr7

23571407

-AQP1chr7

30961680

+
5UTR-3UTRENST00000538367ENST00000409611TRA2Achr7

23571408

-AQP1chr7

30961681

+
5UTR-3UTRENST00000538367ENST00000409899TRA2Achr7

23571407

-AQP1chr7

30961680

+
5UTR-3UTRENST00000538367ENST00000409899TRA2Achr7

23571408

-AQP1chr7

30961681

+
5UTR-3UTRENST00000538367ENST00000441328TRA2Achr7

23571407

-AQP1chr7

30961680

+
5UTR-3UTRENST00000538367ENST00000441328TRA2Achr7

23571408

-AQP1chr7

30961681

+
5UTR-3UTRENST00000538367ENST00000482461TRA2Achr7

23571407

-AQP1chr7

30961680

+
5UTR-3UTRENST00000538367ENST00000482461TRA2Achr7

23571408

-AQP1chr7

30961681

+
In-frameENST00000297071ENST00000311813TRA2Achr7

23571407

-AQP1chr7

30961680

+
In-frameENST00000297071ENST00000311813TRA2Achr7

23571408

-AQP1chr7

30961681

+
In-frameENST00000297071ENST00000434909TRA2Achr7

23571407

-AQP1chr7

30961680

+
In-frameENST00000297071ENST00000434909TRA2Achr7

23571408

-AQP1chr7

30961681

+
In-frameENST00000297071ENST00000509504TRA2Achr7

23571407

-AQP1chr7

30961680

+
In-frameENST00000297071ENST00000509504TRA2Achr7

23571408

-AQP1chr7

30961681

+
intron-3CDSENST00000474586ENST00000311813TRA2Achr7

23571407

-AQP1chr7

30961680

+
intron-3CDSENST00000474586ENST00000311813TRA2Achr7

23571408

-AQP1chr7

30961681

+
intron-3CDSENST00000474586ENST00000434909TRA2Achr7

23571407

-AQP1chr7

30961680

+
intron-3CDSENST00000474586ENST00000434909TRA2Achr7

23571408

-AQP1chr7

30961681

+
intron-3CDSENST00000474586ENST00000509504TRA2Achr7

23571407

-AQP1chr7

30961680

+
intron-3CDSENST00000474586ENST00000509504TRA2Achr7

23571408

-AQP1chr7

30961681

+
intron-3UTRENST00000474586ENST00000409611TRA2Achr7

23571407

-AQP1chr7

30961680

+
intron-3UTRENST00000474586ENST00000409611TRA2Achr7

23571408

-AQP1chr7

30961681

+
intron-3UTRENST00000474586ENST00000409899TRA2Achr7

23571407

-AQP1chr7

30961680

+
intron-3UTRENST00000474586ENST00000409899TRA2Achr7

23571408

-AQP1chr7

30961681

+
intron-3UTRENST00000474586ENST00000441328TRA2Achr7

23571407

-AQP1chr7

30961680

+
intron-3UTRENST00000474586ENST00000441328TRA2Achr7

23571408

-AQP1chr7

30961681

+
intron-3UTRENST00000474586ENST00000482461TRA2Achr7

23571407

-AQP1chr7

30961680

+
intron-3UTRENST00000474586ENST00000482461TRA2Achr7

23571408

-AQP1chr7

30961681

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000297071TRA2Achr723571408-ENST00000434909AQP1chr730961681+862253217678153
ENST00000297071TRA2Achr723571408-ENST00000509504AQP1chr730961681+862253217678153
ENST00000297071TRA2Achr723571408-ENST00000311813AQP1chr730961681+2566253217678153
ENST00000297071TRA2Achr723571407-ENST00000434909AQP1chr730961680+862253217678153
ENST00000297071TRA2Achr723571407-ENST00000509504AQP1chr730961680+862253217678153
ENST00000297071TRA2Achr723571407-ENST00000311813AQP1chr730961680+2566253217678153

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000297071ENST00000434909TRA2Achr723571408-AQP1chr730961681+0.0073475020.9926524
ENST00000297071ENST00000509504TRA2Achr723571408-AQP1chr730961681+0.0073475020.9926524
ENST00000297071ENST00000311813TRA2Achr723571408-AQP1chr730961681+0.0137676220.9862324
ENST00000297071ENST00000434909TRA2Achr723571407-AQP1chr730961680+0.0073475020.9926524
ENST00000297071ENST00000509504TRA2Achr723571407-AQP1chr730961680+0.0073475020.9926524
ENST00000297071ENST00000311813TRA2Achr723571407-AQP1chr730961680+0.0137676220.9862324

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Fusion Genomic Features for TRA2A-AQP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TRA2Achr723571407-AQP1chr730961680+8.14E-080.9999999
TRA2Achr723571407-AQP1chr730961680+8.14E-080.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for TRA2A-AQP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:23571408/chr7:30961681)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AQP1

Q8NBQ7

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Channel protein that facilitates the transport of water, glycerol and hydrogen peroxide across membrane of cell or organelles guaranteeing intracellular homeostasis in several organes like liver, kidney and brain (PubMed:24845055, PubMed:24918044, PubMed:31546170). In situation of stress, participates in endoplasmic reticulum (ER) homeostasis by regulating redox homeostasis through the transport of hydrogen peroxide across the endoplasmic reticulum membrane thereby regulating the oxidative stress through the NADPH oxidase 2 pathway (PubMed:31546170). Plays a role by maintaining an environment suitable for translation or protein foldings in the ER lumen namely by participating in the PKD1 glycosylation processing resulting in regulation of PKD1 membrane trafficking thereby preventing the accumulation of unfolding protein in ER (By similarity). Plays a role in the proximal tubule function by regulating its endosomal acidification (By similarity). May play a role in postnatal kidney development (By similarity). {ECO:0000250|UniProtKB:Q8BHH1, ECO:0000269|PubMed:24845055, ECO:0000269|PubMed:24918044, ECO:0000269|PubMed:31546170}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneAQP1chr7:23571407chr7:30961680ENST0000031181304159_162128270.0Compositional biasNote=Poly-Arg
TgeneAQP1chr7:23571407chr7:30961680ENST0000040961104159_16277219.0Compositional biasNote=Poly-Arg
TgeneAQP1chr7:23571407chr7:30961680ENST0000040989904159_16213155.0Compositional biasNote=Poly-Arg
TgeneAQP1chr7:23571407chr7:30961680ENST0000044132815159_16245187.0Compositional biasNote=Poly-Arg
TgeneAQP1chr7:23571408chr7:30961681ENST0000031181304159_162128270.0Compositional biasNote=Poly-Arg
TgeneAQP1chr7:23571408chr7:30961681ENST0000040961104159_16277219.0Compositional biasNote=Poly-Arg
TgeneAQP1chr7:23571408chr7:30961681ENST0000040989904159_16213155.0Compositional biasNote=Poly-Arg
TgeneAQP1chr7:23571408chr7:30961681ENST0000044132815159_16245187.0Compositional biasNote=Poly-Arg
TgeneAQP1chr7:23571407chr7:30961680ENST0000031181304187_192128270.0Intramembrane.
TgeneAQP1chr7:23571407chr7:30961680ENST0000031181304193_200128270.0IntramembraneNote=Helical%3B Name%3DHelix E
TgeneAQP1chr7:23571407chr7:30961680ENST0000040961104187_19277219.0Intramembrane.
TgeneAQP1chr7:23571407chr7:30961680ENST0000040961104193_20077219.0IntramembraneNote=Helical%3B Name%3DHelix E
TgeneAQP1chr7:23571407chr7:30961680ENST000004096110477_8477219.0IntramembraneNote=Helical%3B Name%3DHelix B
TgeneAQP1chr7:23571407chr7:30961680ENST0000040989904187_19213155.0Intramembrane.
TgeneAQP1chr7:23571407chr7:30961680ENST0000040989904193_20013155.0IntramembraneNote=Helical%3B Name%3DHelix E
TgeneAQP1chr7:23571407chr7:30961680ENST000004098990471_7613155.0Intramembrane.
TgeneAQP1chr7:23571407chr7:30961680ENST000004098990477_8413155.0IntramembraneNote=Helical%3B Name%3DHelix B
TgeneAQP1chr7:23571407chr7:30961680ENST0000044132815187_19245187.0Intramembrane.
TgeneAQP1chr7:23571407chr7:30961680ENST0000044132815193_20045187.0IntramembraneNote=Helical%3B Name%3DHelix E
TgeneAQP1chr7:23571407chr7:30961680ENST000004413281571_7645187.0Intramembrane.
TgeneAQP1chr7:23571407chr7:30961680ENST000004413281577_8445187.0IntramembraneNote=Helical%3B Name%3DHelix B
TgeneAQP1chr7:23571408chr7:30961681ENST0000031181304187_192128270.0Intramembrane.
TgeneAQP1chr7:23571408chr7:30961681ENST0000031181304193_200128270.0IntramembraneNote=Helical%3B Name%3DHelix E
TgeneAQP1chr7:23571408chr7:30961681ENST0000040961104187_19277219.0Intramembrane.
TgeneAQP1chr7:23571408chr7:30961681ENST0000040961104193_20077219.0IntramembraneNote=Helical%3B Name%3DHelix E
TgeneAQP1chr7:23571408chr7:30961681ENST000004096110477_8477219.0IntramembraneNote=Helical%3B Name%3DHelix B
TgeneAQP1chr7:23571408chr7:30961681ENST0000040989904187_19213155.0Intramembrane.
TgeneAQP1chr7:23571408chr7:30961681ENST0000040989904193_20013155.0IntramembraneNote=Helical%3B Name%3DHelix E
TgeneAQP1chr7:23571408chr7:30961681ENST000004098990471_7613155.0Intramembrane.
TgeneAQP1chr7:23571408chr7:30961681ENST000004098990477_8413155.0IntramembraneNote=Helical%3B Name%3DHelix B
TgeneAQP1chr7:23571408chr7:30961681ENST0000044132815187_19245187.0Intramembrane.
TgeneAQP1chr7:23571408chr7:30961681ENST0000044132815193_20045187.0IntramembraneNote=Helical%3B Name%3DHelix E
TgeneAQP1chr7:23571408chr7:30961681ENST000004413281571_7645187.0Intramembrane.
TgeneAQP1chr7:23571408chr7:30961681ENST000004413281577_8445187.0IntramembraneNote=Helical%3B Name%3DHelix B
TgeneAQP1chr7:23571407chr7:30961680ENST0000031181304192_194128270.0MotifNote=NPA 2
TgeneAQP1chr7:23571407chr7:30961680ENST0000040961104192_19477219.0MotifNote=NPA 2
TgeneAQP1chr7:23571407chr7:30961680ENST000004096110476_7877219.0MotifNote=NPA 1
TgeneAQP1chr7:23571407chr7:30961680ENST0000040989904192_19413155.0MotifNote=NPA 2
TgeneAQP1chr7:23571407chr7:30961680ENST000004098990476_7813155.0MotifNote=NPA 1
TgeneAQP1chr7:23571407chr7:30961680ENST0000044132815192_19445187.0MotifNote=NPA 2
TgeneAQP1chr7:23571407chr7:30961680ENST000004413281576_7845187.0MotifNote=NPA 1
TgeneAQP1chr7:23571408chr7:30961681ENST0000031181304192_194128270.0MotifNote=NPA 2
TgeneAQP1chr7:23571408chr7:30961681ENST0000040961104192_19477219.0MotifNote=NPA 2
TgeneAQP1chr7:23571408chr7:30961681ENST000004096110476_7877219.0MotifNote=NPA 1
TgeneAQP1chr7:23571408chr7:30961681ENST0000040989904192_19413155.0MotifNote=NPA 2
TgeneAQP1chr7:23571408chr7:30961681ENST000004098990476_7813155.0MotifNote=NPA 1
TgeneAQP1chr7:23571408chr7:30961681ENST0000044132815192_19445187.0MotifNote=NPA 2
TgeneAQP1chr7:23571408chr7:30961681ENST000004413281576_7845187.0MotifNote=NPA 1
TgeneAQP1chr7:23571407chr7:30961680ENST0000031181304156_166128270.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST0000031181304184_186128270.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST0000031181304201_207128270.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST0000031181304229_269128270.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST0000040961104116_13677219.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST0000040961104156_16677219.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST0000040961104184_18677219.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST0000040961104201_20777219.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST0000040961104229_26977219.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST000004096110485_9477219.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST0000040989904116_13613155.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST0000040989904156_16613155.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST0000040989904184_18613155.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST0000040989904201_20713155.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST0000040989904229_26913155.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST000004098990437_4813155.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST000004098990467_7013155.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST000004098990485_9413155.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST0000044132815116_13645187.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST0000044132815156_16645187.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST0000044132815184_18645187.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST0000044132815201_20745187.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST0000044132815229_26945187.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST000004413281567_7045187.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST000004413281585_9445187.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST0000031181304156_166128270.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST0000031181304184_186128270.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST0000031181304201_207128270.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST0000031181304229_269128270.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST0000040961104116_13677219.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST0000040961104156_16677219.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST0000040961104184_18677219.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST0000040961104201_20777219.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST0000040961104229_26977219.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST000004096110485_9477219.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST0000040989904116_13613155.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST0000040989904156_16613155.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST0000040989904184_18613155.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST0000040989904201_20713155.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST0000040989904229_26913155.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST000004098990437_4813155.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST000004098990467_7013155.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST000004098990485_9413155.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST0000044132815116_13645187.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST0000044132815156_16645187.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST0000044132815184_18645187.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST0000044132815201_20745187.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST0000044132815229_26945187.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST000004413281567_7045187.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST000004413281585_9445187.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST0000031181304137_155128270.0TransmembraneNote=Helical%3B Name%3DHelix 4
TgeneAQP1chr7:23571407chr7:30961680ENST0000031181304167_183128270.0TransmembraneNote=Helical%3B Name%3DHelix 5
TgeneAQP1chr7:23571407chr7:30961680ENST0000031181304208_228128270.0TransmembraneNote=Helical%3B Name%3DHelix 6
TgeneAQP1chr7:23571407chr7:30961680ENST0000040961104137_15577219.0TransmembraneNote=Helical%3B Name%3DHelix 4
TgeneAQP1chr7:23571407chr7:30961680ENST0000040961104167_18377219.0TransmembraneNote=Helical%3B Name%3DHelix 5
TgeneAQP1chr7:23571407chr7:30961680ENST0000040961104208_22877219.0TransmembraneNote=Helical%3B Name%3DHelix 6
TgeneAQP1chr7:23571407chr7:30961680ENST000004096110495_11577219.0TransmembraneNote=Helical%3B Name%3DHelix 3
TgeneAQP1chr7:23571407chr7:30961680ENST0000040989904137_15513155.0TransmembraneNote=Helical%3B Name%3DHelix 4
TgeneAQP1chr7:23571407chr7:30961680ENST0000040989904167_18313155.0TransmembraneNote=Helical%3B Name%3DHelix 5
TgeneAQP1chr7:23571407chr7:30961680ENST0000040989904208_22813155.0TransmembraneNote=Helical%3B Name%3DHelix 6
TgeneAQP1chr7:23571407chr7:30961680ENST000004098990449_6613155.0TransmembraneNote=Helical%3B Name%3DHelix 2
TgeneAQP1chr7:23571407chr7:30961680ENST000004098990495_11513155.0TransmembraneNote=Helical%3B Name%3DHelix 3
TgeneAQP1chr7:23571407chr7:30961680ENST0000044132815137_15545187.0TransmembraneNote=Helical%3B Name%3DHelix 4
TgeneAQP1chr7:23571407chr7:30961680ENST0000044132815167_18345187.0TransmembraneNote=Helical%3B Name%3DHelix 5
TgeneAQP1chr7:23571407chr7:30961680ENST0000044132815208_22845187.0TransmembraneNote=Helical%3B Name%3DHelix 6
TgeneAQP1chr7:23571407chr7:30961680ENST000004413281549_6645187.0TransmembraneNote=Helical%3B Name%3DHelix 2
TgeneAQP1chr7:23571407chr7:30961680ENST000004413281595_11545187.0TransmembraneNote=Helical%3B Name%3DHelix 3
TgeneAQP1chr7:23571408chr7:30961681ENST0000031181304137_155128270.0TransmembraneNote=Helical%3B Name%3DHelix 4
TgeneAQP1chr7:23571408chr7:30961681ENST0000031181304167_183128270.0TransmembraneNote=Helical%3B Name%3DHelix 5
TgeneAQP1chr7:23571408chr7:30961681ENST0000031181304208_228128270.0TransmembraneNote=Helical%3B Name%3DHelix 6
TgeneAQP1chr7:23571408chr7:30961681ENST0000040961104137_15577219.0TransmembraneNote=Helical%3B Name%3DHelix 4
TgeneAQP1chr7:23571408chr7:30961681ENST0000040961104167_18377219.0TransmembraneNote=Helical%3B Name%3DHelix 5
TgeneAQP1chr7:23571408chr7:30961681ENST0000040961104208_22877219.0TransmembraneNote=Helical%3B Name%3DHelix 6
TgeneAQP1chr7:23571408chr7:30961681ENST000004096110495_11577219.0TransmembraneNote=Helical%3B Name%3DHelix 3
TgeneAQP1chr7:23571408chr7:30961681ENST0000040989904137_15513155.0TransmembraneNote=Helical%3B Name%3DHelix 4
TgeneAQP1chr7:23571408chr7:30961681ENST0000040989904167_18313155.0TransmembraneNote=Helical%3B Name%3DHelix 5
TgeneAQP1chr7:23571408chr7:30961681ENST0000040989904208_22813155.0TransmembraneNote=Helical%3B Name%3DHelix 6
TgeneAQP1chr7:23571408chr7:30961681ENST000004098990449_6613155.0TransmembraneNote=Helical%3B Name%3DHelix 2
TgeneAQP1chr7:23571408chr7:30961681ENST000004098990495_11513155.0TransmembraneNote=Helical%3B Name%3DHelix 3
TgeneAQP1chr7:23571408chr7:30961681ENST0000044132815137_15545187.0TransmembraneNote=Helical%3B Name%3DHelix 4
TgeneAQP1chr7:23571408chr7:30961681ENST0000044132815167_18345187.0TransmembraneNote=Helical%3B Name%3DHelix 5
TgeneAQP1chr7:23571408chr7:30961681ENST0000044132815208_22845187.0TransmembraneNote=Helical%3B Name%3DHelix 6
TgeneAQP1chr7:23571408chr7:30961681ENST000004413281549_6645187.0TransmembraneNote=Helical%3B Name%3DHelix 2
TgeneAQP1chr7:23571408chr7:30961681ENST000004413281595_11545187.0TransmembraneNote=Helical%3B Name%3DHelix 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRA2Achr7:23571407chr7:30961680ENST00000297071-18226_28212283.0Compositional biasNote=Arg/Ser-rich (RS2 domain)
HgeneTRA2Achr7:23571407chr7:30961680ENST00000297071-1830_11212283.0Compositional biasNote=Arg/Ser-rich (RS1 domain)
HgeneTRA2Achr7:23571408chr7:30961681ENST00000297071-18226_28212283.0Compositional biasNote=Arg/Ser-rich (RS2 domain)
HgeneTRA2Achr7:23571408chr7:30961681ENST00000297071-1830_11212283.0Compositional biasNote=Arg/Ser-rich (RS1 domain)
HgeneTRA2Achr7:23571407chr7:30961680ENST00000297071-18119_19712283.0DomainRRM
HgeneTRA2Achr7:23571408chr7:30961681ENST00000297071-18119_19712283.0DomainRRM
HgeneTRA2Achr7:23571407chr7:30961680ENST00000297071-18198_22512283.0RegionNote=Linker
HgeneTRA2Achr7:23571408chr7:30961681ENST00000297071-18198_22512283.0RegionNote=Linker
TgeneAQP1chr7:23571407chr7:30961680ENST000003118130471_76128270.0Intramembrane.
TgeneAQP1chr7:23571407chr7:30961680ENST000003118130477_84128270.0IntramembraneNote=Helical%3B Name%3DHelix B
TgeneAQP1chr7:23571407chr7:30961680ENST000004096110471_7677219.0Intramembrane.
TgeneAQP1chr7:23571408chr7:30961681ENST000003118130471_76128270.0Intramembrane.
TgeneAQP1chr7:23571408chr7:30961681ENST000003118130477_84128270.0IntramembraneNote=Helical%3B Name%3DHelix B
TgeneAQP1chr7:23571408chr7:30961681ENST000004096110471_7677219.0Intramembrane.
TgeneAQP1chr7:23571407chr7:30961680ENST000003118130476_78128270.0MotifNote=NPA 1
TgeneAQP1chr7:23571408chr7:30961681ENST000003118130476_78128270.0MotifNote=NPA 1
TgeneAQP1chr7:23571407chr7:30961680ENST0000031181304116_136128270.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST00000311813042_7128270.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST000003118130437_48128270.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST000003118130467_70128270.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST000003118130485_94128270.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST00000409611042_777219.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST000004096110437_4877219.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST000004096110467_7077219.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST00000409899042_713155.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST00000441328152_745187.0Topological domainCytoplasmic
TgeneAQP1chr7:23571407chr7:30961680ENST000004413281537_4845187.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST0000031181304116_136128270.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST00000311813042_7128270.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST000003118130437_48128270.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST000003118130467_70128270.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST000003118130485_94128270.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST00000409611042_777219.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST000004096110437_4877219.0Topological domainExtracellular
TgeneAQP1chr7:23571408chr7:30961681ENST000004096110467_7077219.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST00000409899042_713155.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST00000441328152_745187.0Topological domainCytoplasmic
TgeneAQP1chr7:23571408chr7:30961681ENST000004413281537_4845187.0Topological domainExtracellular
TgeneAQP1chr7:23571407chr7:30961680ENST000003118130449_66128270.0TransmembraneNote=Helical%3B Name%3DHelix 2
TgeneAQP1chr7:23571407chr7:30961680ENST00000311813048_36128270.0TransmembraneNote=Helical%3B Name%3DHelix 1
TgeneAQP1chr7:23571407chr7:30961680ENST000003118130495_115128270.0TransmembraneNote=Helical%3B Name%3DHelix 3
TgeneAQP1chr7:23571407chr7:30961680ENST000004096110449_6677219.0TransmembraneNote=Helical%3B Name%3DHelix 2
TgeneAQP1chr7:23571407chr7:30961680ENST00000409611048_3677219.0TransmembraneNote=Helical%3B Name%3DHelix 1
TgeneAQP1chr7:23571407chr7:30961680ENST00000409899048_3613155.0TransmembraneNote=Helical%3B Name%3DHelix 1
TgeneAQP1chr7:23571407chr7:30961680ENST00000441328158_3645187.0TransmembraneNote=Helical%3B Name%3DHelix 1
TgeneAQP1chr7:23571408chr7:30961681ENST000003118130449_66128270.0TransmembraneNote=Helical%3B Name%3DHelix 2
TgeneAQP1chr7:23571408chr7:30961681ENST00000311813048_36128270.0TransmembraneNote=Helical%3B Name%3DHelix 1
TgeneAQP1chr7:23571408chr7:30961681ENST000003118130495_115128270.0TransmembraneNote=Helical%3B Name%3DHelix 3
TgeneAQP1chr7:23571408chr7:30961681ENST000004096110449_6677219.0TransmembraneNote=Helical%3B Name%3DHelix 2
TgeneAQP1chr7:23571408chr7:30961681ENST00000409611048_3677219.0TransmembraneNote=Helical%3B Name%3DHelix 1
TgeneAQP1chr7:23571408chr7:30961681ENST00000409899048_3613155.0TransmembraneNote=Helical%3B Name%3DHelix 1
TgeneAQP1chr7:23571408chr7:30961681ENST00000441328158_3645187.0TransmembraneNote=Helical%3B Name%3DHelix 1


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Fusion Gene Sequence for TRA2A-AQP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>93572_93572_1_TRA2A-AQP1_TRA2A_chr7_23571407_ENST00000297071_AQP1_chr7_30961680_ENST00000311813_length(transcript)=2566nt_BP=253nt
GCCCGCCCCCTTTACGTCGTGCTCTGAGGAGGCCAGGAGATTTCTGGCGGCGCCGGCGCCATTTTGCTGGAGCCTGCGACCGAGTGGGAG
TGGAGTGGAGCGGCTGTGGTTGCCGACTCTTTCCTCTTCCCCACGGTCCAGTCAGCGGGTTAATTAGGCCATCGGCCCTCGAGCCGAGAC
TTGTCTCTTATTTAGTTCTGGGGAGCGCCTCGTCGACATGAGTGATGTGGAGGAAAACAACTTCGAGGGCAGACTGGCTGATGGTGTGAA
CTCGGGCCAGGGCCTGGGCATCGAGATCATCGGGACCCTCCAGCTGGTGCTATGCGTGCTGGCTACTACCGACCGGAGGCGCCGTGACCT
TGGTGGCTCAGCCCCCCTTGCCATCGGCCTCTCTGTAGCCCTTGGACACCTCCTGGCTATTGACTACACTGGCTGTGGGATTAACCCTGC
TCGGTCCTTTGGCTCCGCGGTGATCACACACAACTTCAGCAACCACTGGATTTTCTGGGTGGGGCCATTCATCGGGGGAGCCCTGGCTGT
ACTCATCTACGACTTCATCCTGGCCCCACGCAGCAGTGACCTCACAGACCGCGTGAAGGTGTGGACCAGCGGCCAGGTGGAGGAGTATGA
CCTGGATGCCGACGACATCAACTCCAGGGTGGAGATGAAGCCCAAATAGAAGGGGTCTGGCCCGGGCATCCACGTAGGGGGCAGGGGCAG
GGGCGGGCGGAGGGAGGGGAGGGGTGAAATCCATACTGTAGACACTCTGACAAGCTGGCCAAAGTCACTTCCCCAAGATCTGCCAGACCT
GCATGGTCAAGCCTCTTATGGGGGTGTTTCTATCTCTTTCTTTCTCTTTCTGTTTCCTGGCCTCAGAGCTTCCTGGGGACCAAGATTTAC
CAATTCACCCACTCCCTTGAAGTTGTGGAGGAGGTGAAAGAAAGGGACCCACCTGCTAGTCGCCCCTCAGAGCATGATGGGAGGTGTGCC
AGAAAGTCCCCCCTCGCCCCAAAGTTGCTCACCGACTCACCTGCGCAAGTGCCTGGGATTCTACCGTAATTGCTTTGTGCCTTTGGGCAC
GGCCCTCCTTCTTTTCCTAACATGCACCTTGCTCCCAATGGTGCTTGGAGGGGGAAGAGATCCCAGGAGGTGCAGTGGAGGGGGCAAGCT
TTGCTCCTTCAGTTCTGCTTGCTCCCAAGCCCCTGACCCGCTCGGACTTACTGCCTGACCTTGGAATCGTCCCTATATCAGGGCCTGAGT
GACCTCCTTCTGCAAAGTGGCAGGGACCGGCAGAGCTCTACAGGCCTGCAGCCCCTAAGTGCAAACACAGCATGGGTCCAGAAGACGTGG
TCTAGACCAGGGCTGCTCTTTCCACTTGCCCTGTGTTCTTTCCCCAGGGGCATGACTGTCGCCACACGCCTCTGTGTACATGTGTGCAGA
GCAGACAGGCTACAAAGCAGAGATCGACAGACAGCCAGGTAGTTGGAACTTTCTGTTCCCTATGGAGAGGCTTCCCTACACAGGGCCTGC
TATTGCAGAATGAAGCCATTTAGAGGGTGAAGGAGAAATACCCATGTTACTTCTCTGAGTTTTAGTTGGTCTTTCCATCTATCACTGCAT
TATCTTGCTCATTCTTCAGTTCTCTACTCCCTCTTGTCAGTGTAGACACAGGTCACCATTATGCTGGTGTATGTTTATCAAAGAGCACTT
GAGCTGTCTGAAGCCCAAAGCCTGAGGACAGAAAGACCCTGATGCAGGTCAGCCCATGGAGGCAGATGCCCTTGCTGGGCCTGGGGGTTT
TCCAAGCCCTCAGCTGGTCCTGACCAGGATGGAGCAAGCTCTTCCCTTGCTCATGAGCTCCTGATCAGAGGCATTTGAGCAGCTGAATAA
CCTGCACAGGCTTGCTGTATGACCCCTGGCCACAGCCTTCCCTCTGCATTGACCTGGAGGGGAGAGGTCAGCCTTGACCTAATGAGGTAG
CTATAGTTGCAGCCCAAGGACAGTTCAGAGATCAGGATCAGCTTTGAAGGCTGGATTCTATCTACATAAGTCCTTTCAATTCCACCAGGG
CCAGAGCAGCTCCACCACTGTGCACTTAGCCATGATGGCAACAGAAACCAAGAGACACAATTACGCAGGTATTTAGAAGCAGAGGGACAA
CCAGAAGGCCCTTAACTATCACCAGTGCATCACATCTGCACACTCTCTTCTCCATTCCCTAGCAGGAACTTCTAGCTCATTTAACAGATA
AAGAAACTGAGGCCCACGGTTTCAGCTAGACAATGATTTGGCCAGGCCTAGTAACCAAGGCCCTGTCTCTGGCTACTCCCTGGACCACGA
GGCTGATTCCTCTCATTTCCAGCTTCTCAGTTTCTGCCTGGGCAATGGCCAGGGGCCAGGAGTGGGGAGAGTTGTGATGGAGGGGAGAGG
GGTCACACCCACCCCCTGCCTGGTTCTAGGCTGCTGCACACCAAGGCCCTGCATCTGTCTGCTCTGCATATATGTCTCTTTGGAGTTGGA

>93572_93572_1_TRA2A-AQP1_TRA2A_chr7_23571407_ENST00000297071_AQP1_chr7_30961680_ENST00000311813_length(amino acids)=153AA_BP=12
MSDVEENNFEGRLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNF

--------------------------------------------------------------
>93572_93572_2_TRA2A-AQP1_TRA2A_chr7_23571407_ENST00000297071_AQP1_chr7_30961680_ENST00000434909_length(transcript)=862nt_BP=253nt
GCCCGCCCCCTTTACGTCGTGCTCTGAGGAGGCCAGGAGATTTCTGGCGGCGCCGGCGCCATTTTGCTGGAGCCTGCGACCGAGTGGGAG
TGGAGTGGAGCGGCTGTGGTTGCCGACTCTTTCCTCTTCCCCACGGTCCAGTCAGCGGGTTAATTAGGCCATCGGCCCTCGAGCCGAGAC
TTGTCTCTTATTTAGTTCTGGGGAGCGCCTCGTCGACATGAGTGATGTGGAGGAAAACAACTTCGAGGGCAGACTGGCTGATGGTGTGAA
CTCGGGCCAGGGCCTGGGCATCGAGATCATCGGGACCCTCCAGCTGGTGCTATGCGTGCTGGCTACTACCGACCGGAGGCGCCGTGACCT
TGGTGGCTCAGCCCCCCTTGCCATCGGCCTCTCTGTAGCCCTTGGACACCTCCTGGCTATTGACTACACTGGCTGTGGGATTAACCCTGC
TCGGTCCTTTGGCTCCGCGGTGATCACACACAACTTCAGCAACCACTGGATTTTCTGGGTGGGGCCATTCATCGGGGGAGCCCTGGCTGT
ACTCATCTACGACTTCATCCTGGCCCCACGCAGCAGTGACCTCACAGACCGCGTGAAGGTGTGGACCAGCGGCCAGGTGGAGGAGTATGA
CCTGGATGCCGACGACATCAACTCCAGGGTGGAGATGAAGCCCAAATAGAAGGGGTCTGGCCCGGGCATCCACGTAGGGGGCAGGGGCAG
GGGCGGGCGGAGGGAGGGGAGGGGTGAAATCCATACTGTAGACACTCTGACAAGCTGGCCAAAGTCACTTCCCCAAGATCTGCCAGACCT

>93572_93572_2_TRA2A-AQP1_TRA2A_chr7_23571407_ENST00000297071_AQP1_chr7_30961680_ENST00000434909_length(amino acids)=153AA_BP=12
MSDVEENNFEGRLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNF

--------------------------------------------------------------
>93572_93572_3_TRA2A-AQP1_TRA2A_chr7_23571407_ENST00000297071_AQP1_chr7_30961680_ENST00000509504_length(transcript)=862nt_BP=253nt
GCCCGCCCCCTTTACGTCGTGCTCTGAGGAGGCCAGGAGATTTCTGGCGGCGCCGGCGCCATTTTGCTGGAGCCTGCGACCGAGTGGGAG
TGGAGTGGAGCGGCTGTGGTTGCCGACTCTTTCCTCTTCCCCACGGTCCAGTCAGCGGGTTAATTAGGCCATCGGCCCTCGAGCCGAGAC
TTGTCTCTTATTTAGTTCTGGGGAGCGCCTCGTCGACATGAGTGATGTGGAGGAAAACAACTTCGAGGGCAGACTGGCTGATGGTGTGAA
CTCGGGCCAGGGCCTGGGCATCGAGATCATCGGGACCCTCCAGCTGGTGCTATGCGTGCTGGCTACTACCGACCGGAGGCGCCGTGACCT
TGGTGGCTCAGCCCCCCTTGCCATCGGCCTCTCTGTAGCCCTTGGACACCTCCTGGCTATTGACTACACTGGCTGTGGGATTAACCCTGC
TCGGTCCTTTGGCTCCGCGGTGATCACACACAACTTCAGCAACCACTGGATTTTCTGGGTGGGGCCATTCATCGGGGGAGCCCTGGCTGT
ACTCATCTACGACTTCATCCTGGCCCCACGCAGCAGTGACCTCACAGACCGCGTGAAGGTGTGGACCAGCGGCCAGGTGGAGGAGTATGA
CCTGGATGCCGACGACATCAACTCCAGGGTGGAGATGAAGCCCAAATAGAAGGGGTCTGGCCCGGGCATCCACGTAGGGGGCAGGGGCAG
GGGCGGGCGGAGGGAGGGGAGGGGTGAAATCCATACTGTAGACACTCTGACAAGCTGGCCAAAGTCACTTCCCCAAGATCTGCCAGACCT

>93572_93572_3_TRA2A-AQP1_TRA2A_chr7_23571407_ENST00000297071_AQP1_chr7_30961680_ENST00000509504_length(amino acids)=153AA_BP=12
MSDVEENNFEGRLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNF

--------------------------------------------------------------
>93572_93572_4_TRA2A-AQP1_TRA2A_chr7_23571408_ENST00000297071_AQP1_chr7_30961681_ENST00000311813_length(transcript)=2566nt_BP=253nt
GCCCGCCCCCTTTACGTCGTGCTCTGAGGAGGCCAGGAGATTTCTGGCGGCGCCGGCGCCATTTTGCTGGAGCCTGCGACCGAGTGGGAG
TGGAGTGGAGCGGCTGTGGTTGCCGACTCTTTCCTCTTCCCCACGGTCCAGTCAGCGGGTTAATTAGGCCATCGGCCCTCGAGCCGAGAC
TTGTCTCTTATTTAGTTCTGGGGAGCGCCTCGTCGACATGAGTGATGTGGAGGAAAACAACTTCGAGGGCAGACTGGCTGATGGTGTGAA
CTCGGGCCAGGGCCTGGGCATCGAGATCATCGGGACCCTCCAGCTGGTGCTATGCGTGCTGGCTACTACCGACCGGAGGCGCCGTGACCT
TGGTGGCTCAGCCCCCCTTGCCATCGGCCTCTCTGTAGCCCTTGGACACCTCCTGGCTATTGACTACACTGGCTGTGGGATTAACCCTGC
TCGGTCCTTTGGCTCCGCGGTGATCACACACAACTTCAGCAACCACTGGATTTTCTGGGTGGGGCCATTCATCGGGGGAGCCCTGGCTGT
ACTCATCTACGACTTCATCCTGGCCCCACGCAGCAGTGACCTCACAGACCGCGTGAAGGTGTGGACCAGCGGCCAGGTGGAGGAGTATGA
CCTGGATGCCGACGACATCAACTCCAGGGTGGAGATGAAGCCCAAATAGAAGGGGTCTGGCCCGGGCATCCACGTAGGGGGCAGGGGCAG
GGGCGGGCGGAGGGAGGGGAGGGGTGAAATCCATACTGTAGACACTCTGACAAGCTGGCCAAAGTCACTTCCCCAAGATCTGCCAGACCT
GCATGGTCAAGCCTCTTATGGGGGTGTTTCTATCTCTTTCTTTCTCTTTCTGTTTCCTGGCCTCAGAGCTTCCTGGGGACCAAGATTTAC
CAATTCACCCACTCCCTTGAAGTTGTGGAGGAGGTGAAAGAAAGGGACCCACCTGCTAGTCGCCCCTCAGAGCATGATGGGAGGTGTGCC
AGAAAGTCCCCCCTCGCCCCAAAGTTGCTCACCGACTCACCTGCGCAAGTGCCTGGGATTCTACCGTAATTGCTTTGTGCCTTTGGGCAC
GGCCCTCCTTCTTTTCCTAACATGCACCTTGCTCCCAATGGTGCTTGGAGGGGGAAGAGATCCCAGGAGGTGCAGTGGAGGGGGCAAGCT
TTGCTCCTTCAGTTCTGCTTGCTCCCAAGCCCCTGACCCGCTCGGACTTACTGCCTGACCTTGGAATCGTCCCTATATCAGGGCCTGAGT
GACCTCCTTCTGCAAAGTGGCAGGGACCGGCAGAGCTCTACAGGCCTGCAGCCCCTAAGTGCAAACACAGCATGGGTCCAGAAGACGTGG
TCTAGACCAGGGCTGCTCTTTCCACTTGCCCTGTGTTCTTTCCCCAGGGGCATGACTGTCGCCACACGCCTCTGTGTACATGTGTGCAGA
GCAGACAGGCTACAAAGCAGAGATCGACAGACAGCCAGGTAGTTGGAACTTTCTGTTCCCTATGGAGAGGCTTCCCTACACAGGGCCTGC
TATTGCAGAATGAAGCCATTTAGAGGGTGAAGGAGAAATACCCATGTTACTTCTCTGAGTTTTAGTTGGTCTTTCCATCTATCACTGCAT
TATCTTGCTCATTCTTCAGTTCTCTACTCCCTCTTGTCAGTGTAGACACAGGTCACCATTATGCTGGTGTATGTTTATCAAAGAGCACTT
GAGCTGTCTGAAGCCCAAAGCCTGAGGACAGAAAGACCCTGATGCAGGTCAGCCCATGGAGGCAGATGCCCTTGCTGGGCCTGGGGGTTT
TCCAAGCCCTCAGCTGGTCCTGACCAGGATGGAGCAAGCTCTTCCCTTGCTCATGAGCTCCTGATCAGAGGCATTTGAGCAGCTGAATAA
CCTGCACAGGCTTGCTGTATGACCCCTGGCCACAGCCTTCCCTCTGCATTGACCTGGAGGGGAGAGGTCAGCCTTGACCTAATGAGGTAG
CTATAGTTGCAGCCCAAGGACAGTTCAGAGATCAGGATCAGCTTTGAAGGCTGGATTCTATCTACATAAGTCCTTTCAATTCCACCAGGG
CCAGAGCAGCTCCACCACTGTGCACTTAGCCATGATGGCAACAGAAACCAAGAGACACAATTACGCAGGTATTTAGAAGCAGAGGGACAA
CCAGAAGGCCCTTAACTATCACCAGTGCATCACATCTGCACACTCTCTTCTCCATTCCCTAGCAGGAACTTCTAGCTCATTTAACAGATA
AAGAAACTGAGGCCCACGGTTTCAGCTAGACAATGATTTGGCCAGGCCTAGTAACCAAGGCCCTGTCTCTGGCTACTCCCTGGACCACGA
GGCTGATTCCTCTCATTTCCAGCTTCTCAGTTTCTGCCTGGGCAATGGCCAGGGGCCAGGAGTGGGGAGAGTTGTGATGGAGGGGAGAGG
GGTCACACCCACCCCCTGCCTGGTTCTAGGCTGCTGCACACCAAGGCCCTGCATCTGTCTGCTCTGCATATATGTCTCTTTGGAGTTGGA

>93572_93572_4_TRA2A-AQP1_TRA2A_chr7_23571408_ENST00000297071_AQP1_chr7_30961681_ENST00000311813_length(amino acids)=153AA_BP=12
MSDVEENNFEGRLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNF

--------------------------------------------------------------
>93572_93572_5_TRA2A-AQP1_TRA2A_chr7_23571408_ENST00000297071_AQP1_chr7_30961681_ENST00000434909_length(transcript)=862nt_BP=253nt
GCCCGCCCCCTTTACGTCGTGCTCTGAGGAGGCCAGGAGATTTCTGGCGGCGCCGGCGCCATTTTGCTGGAGCCTGCGACCGAGTGGGAG
TGGAGTGGAGCGGCTGTGGTTGCCGACTCTTTCCTCTTCCCCACGGTCCAGTCAGCGGGTTAATTAGGCCATCGGCCCTCGAGCCGAGAC
TTGTCTCTTATTTAGTTCTGGGGAGCGCCTCGTCGACATGAGTGATGTGGAGGAAAACAACTTCGAGGGCAGACTGGCTGATGGTGTGAA
CTCGGGCCAGGGCCTGGGCATCGAGATCATCGGGACCCTCCAGCTGGTGCTATGCGTGCTGGCTACTACCGACCGGAGGCGCCGTGACCT
TGGTGGCTCAGCCCCCCTTGCCATCGGCCTCTCTGTAGCCCTTGGACACCTCCTGGCTATTGACTACACTGGCTGTGGGATTAACCCTGC
TCGGTCCTTTGGCTCCGCGGTGATCACACACAACTTCAGCAACCACTGGATTTTCTGGGTGGGGCCATTCATCGGGGGAGCCCTGGCTGT
ACTCATCTACGACTTCATCCTGGCCCCACGCAGCAGTGACCTCACAGACCGCGTGAAGGTGTGGACCAGCGGCCAGGTGGAGGAGTATGA
CCTGGATGCCGACGACATCAACTCCAGGGTGGAGATGAAGCCCAAATAGAAGGGGTCTGGCCCGGGCATCCACGTAGGGGGCAGGGGCAG
GGGCGGGCGGAGGGAGGGGAGGGGTGAAATCCATACTGTAGACACTCTGACAAGCTGGCCAAAGTCACTTCCCCAAGATCTGCCAGACCT

>93572_93572_5_TRA2A-AQP1_TRA2A_chr7_23571408_ENST00000297071_AQP1_chr7_30961681_ENST00000434909_length(amino acids)=153AA_BP=12
MSDVEENNFEGRLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNF

--------------------------------------------------------------
>93572_93572_6_TRA2A-AQP1_TRA2A_chr7_23571408_ENST00000297071_AQP1_chr7_30961681_ENST00000509504_length(transcript)=862nt_BP=253nt
GCCCGCCCCCTTTACGTCGTGCTCTGAGGAGGCCAGGAGATTTCTGGCGGCGCCGGCGCCATTTTGCTGGAGCCTGCGACCGAGTGGGAG
TGGAGTGGAGCGGCTGTGGTTGCCGACTCTTTCCTCTTCCCCACGGTCCAGTCAGCGGGTTAATTAGGCCATCGGCCCTCGAGCCGAGAC
TTGTCTCTTATTTAGTTCTGGGGAGCGCCTCGTCGACATGAGTGATGTGGAGGAAAACAACTTCGAGGGCAGACTGGCTGATGGTGTGAA
CTCGGGCCAGGGCCTGGGCATCGAGATCATCGGGACCCTCCAGCTGGTGCTATGCGTGCTGGCTACTACCGACCGGAGGCGCCGTGACCT
TGGTGGCTCAGCCCCCCTTGCCATCGGCCTCTCTGTAGCCCTTGGACACCTCCTGGCTATTGACTACACTGGCTGTGGGATTAACCCTGC
TCGGTCCTTTGGCTCCGCGGTGATCACACACAACTTCAGCAACCACTGGATTTTCTGGGTGGGGCCATTCATCGGGGGAGCCCTGGCTGT
ACTCATCTACGACTTCATCCTGGCCCCACGCAGCAGTGACCTCACAGACCGCGTGAAGGTGTGGACCAGCGGCCAGGTGGAGGAGTATGA
CCTGGATGCCGACGACATCAACTCCAGGGTGGAGATGAAGCCCAAATAGAAGGGGTCTGGCCCGGGCATCCACGTAGGGGGCAGGGGCAG
GGGCGGGCGGAGGGAGGGGAGGGGTGAAATCCATACTGTAGACACTCTGACAAGCTGGCCAAAGTCACTTCCCCAAGATCTGCCAGACCT

>93572_93572_6_TRA2A-AQP1_TRA2A_chr7_23571408_ENST00000297071_AQP1_chr7_30961681_ENST00000509504_length(amino acids)=153AA_BP=12
MSDVEENNFEGRLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNF

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TRA2A-AQP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TRA2A-AQP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TRA2A-AQP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource