FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:TRAF2-CAPN2 (FusionGDB2 ID:93644)

Fusion Gene Summary for TRAF2-CAPN2

check button Fusion gene summary
Fusion gene informationFusion gene name: TRAF2-CAPN2
Fusion gene ID: 93644
HgeneTgene
Gene symbol

TRAF2

CAPN2

Gene ID

10010

824

Gene nameTRAF family member associated NFKB activatorcalpain 2
SynonymsI-TRAF|ITRAF|TRAF2CANP2|CANPL2|CANPml|mCANP
Cytomap

2q24.2

1q41

Type of geneprotein-codingprotein-coding
DescriptionTRAF family member-associated NF-kappa-B activatorTRAF-interacting proteincalpain-2 catalytic subunitCANP 2M-calpaincalcium-activated neutral proteinase 2calpain 2, (m/II) large subunitcalpain 2, large [catalytic] subunitcalpain 2, large subunitcalpain M-typecalpain, large polypeptide L2millimolar-calpain
Modification date2020031320200313
UniProtAcc

TNIK

P17655

Ensembl transtripts involved in fusion geneENST00000247668, ENST00000359662, 
ENST00000536468, ENST00000482854, 
ENST00000474026, ENST00000295006, 
ENST00000433674, 
Fusion gene scores* DoF score7 X 6 X 6=25211 X 7 X 7=539
# samples 711
** MAII scorelog2(7/252*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/539*10)=-2.29278174922785
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TRAF2 [Title/Abstract] AND CAPN2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTRAF2(139794124)-CAPN2(223946971), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCAPN2

GO:0051603

proteolysis involved in cellular protein catabolic process

12150984


check buttonFusion gene breakpoints across TRAF2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CAPN2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-A4IZTRAF2chr9

139794124

+CAPN2chr1

223946971

+


Top

Fusion Gene ORF analysis for TRAF2-CAPN2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000247668ENST00000474026TRAF2chr9

139794124

+CAPN2chr1

223946971

+
5CDS-3UTRENST00000359662ENST00000474026TRAF2chr9

139794124

+CAPN2chr1

223946971

+
5CDS-3UTRENST00000536468ENST00000474026TRAF2chr9

139794124

+CAPN2chr1

223946971

+
In-frameENST00000247668ENST00000295006TRAF2chr9

139794124

+CAPN2chr1

223946971

+
In-frameENST00000247668ENST00000433674TRAF2chr9

139794124

+CAPN2chr1

223946971

+
In-frameENST00000359662ENST00000295006TRAF2chr9

139794124

+CAPN2chr1

223946971

+
In-frameENST00000359662ENST00000433674TRAF2chr9

139794124

+CAPN2chr1

223946971

+
In-frameENST00000536468ENST00000295006TRAF2chr9

139794124

+CAPN2chr1

223946971

+
In-frameENST00000536468ENST00000433674TRAF2chr9

139794124

+CAPN2chr1

223946971

+
intron-3CDSENST00000482854ENST00000295006TRAF2chr9

139794124

+CAPN2chr1

223946971

+
intron-3CDSENST00000482854ENST00000433674TRAF2chr9

139794124

+CAPN2chr1

223946971

+
intron-3UTRENST00000482854ENST00000474026TRAF2chr9

139794124

+CAPN2chr1

223946971

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000536468TRAF2chr9139794124+ENST00000433674CAPN2chr1223946971+23854401491225358
ENST00000536468TRAF2chr9139794124+ENST00000295006CAPN2chr1223946971+23874401491225358
ENST00000247668TRAF2chr9139794124+ENST00000433674CAPN2chr1223946971+2264319281104358
ENST00000247668TRAF2chr9139794124+ENST00000295006CAPN2chr1223946971+2266319281104358
ENST00000359662TRAF2chr9139794124+ENST00000433674CAPN2chr1223946971+2257312211097358
ENST00000359662TRAF2chr9139794124+ENST00000295006CAPN2chr1223946971+2259312211097358

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000536468ENST00000433674TRAF2chr9139794124+CAPN2chr1223946971+0.0006257560.9993742
ENST00000536468ENST00000295006TRAF2chr9139794124+CAPN2chr1223946971+0.0006308140.9993692
ENST00000247668ENST00000433674TRAF2chr9139794124+CAPN2chr1223946971+0.000436310.99956363
ENST00000247668ENST00000295006TRAF2chr9139794124+CAPN2chr1223946971+0.0004392470.9995608
ENST00000359662ENST00000433674TRAF2chr9139794124+CAPN2chr1223946971+0.0004459570.999554
ENST00000359662ENST00000295006TRAF2chr9139794124+CAPN2chr1223946971+0.0004506090.9995493

Top

Fusion Genomic Features for TRAF2-CAPN2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TRAF2chr9139794124+CAPN2chr1223946971+9.44E-111
TRAF2chr9139794124+CAPN2chr1223946971+9.44E-111

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for TRAF2-CAPN2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:139794124/chr1:223946971)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
TRAF2

TNIK

CAPN2

P17655

1360FUNCTION: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity). {ECO:0000250|UniProtKB:O08529, ECO:0000269|PubMed:17650508}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRAF2chr9:139794124chr1:223946971ENST00000247668+31134_7389502.0Zinc fingerRING-type
HgeneTRAF2chr9:139794124chr1:223946971ENST00000359662+31134_7389554.0Zinc fingerRING-type
HgeneTRAF2chr9:139794124chr1:223946971ENST00000536468+41234_7389502.0Zinc fingerRING-type
TgeneCAPN2chr9:139794124chr1:223946971ENST000002950061021585_596439701.0Calcium bindingNote=1
TgeneCAPN2chr9:139794124chr1:223946971ENST000002950061021615_626439701.0Calcium bindingNote=2
TgeneCAPN2chr9:139794124chr1:223946971ENST000004336741021585_596361623.0Calcium bindingNote=1
TgeneCAPN2chr9:139794124chr1:223946971ENST000004336741021615_626361623.0Calcium bindingNote=2
TgeneCAPN2chr9:139794124chr1:223946971ENST000002950061021572_605439701.0DomainEF-hand 1
TgeneCAPN2chr9:139794124chr1:223946971ENST000002950061021602_637439701.0DomainEF-hand 2
TgeneCAPN2chr9:139794124chr1:223946971ENST000002950061021667_700439701.0DomainEF-hand 3
TgeneCAPN2chr9:139794124chr1:223946971ENST000004336741021572_605361623.0DomainEF-hand 1
TgeneCAPN2chr9:139794124chr1:223946971ENST000004336741021602_637361623.0DomainEF-hand 2
TgeneCAPN2chr9:139794124chr1:223946971ENST000004336741021667_700361623.0DomainEF-hand 3
TgeneCAPN2chr9:139794124chr1:223946971ENST000002950061021515_529439701.0RegionNote=Linker
TgeneCAPN2chr9:139794124chr1:223946971ENST000002950061021530_700439701.0RegionNote=Domain IV
TgeneCAPN2chr9:139794124chr1:223946971ENST000004336741021515_529361623.0RegionNote=Linker
TgeneCAPN2chr9:139794124chr1:223946971ENST000004336741021530_700361623.0RegionNote=Domain IV

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRAF2chr9:139794124chr1:223946971ENST00000247668+311299_34889502.0Coiled coilOntology_term=ECO:0000269
HgeneTRAF2chr9:139794124chr1:223946971ENST00000359662+311299_34889554.0Coiled coilOntology_term=ECO:0000269
HgeneTRAF2chr9:139794124chr1:223946971ENST00000536468+412299_34889502.0Coiled coilOntology_term=ECO:0000269
HgeneTRAF2chr9:139794124chr1:223946971ENST00000247668+311351_49689502.0DomainMATH
HgeneTRAF2chr9:139794124chr1:223946971ENST00000359662+311351_49689554.0DomainMATH
HgeneTRAF2chr9:139794124chr1:223946971ENST00000536468+412351_49689502.0DomainMATH
HgeneTRAF2chr9:139794124chr1:223946971ENST00000247668+311124_18089502.0Zinc fingerTRAF-type 1
HgeneTRAF2chr9:139794124chr1:223946971ENST00000247668+311177_23389502.0Zinc fingerTRAF-type 2
HgeneTRAF2chr9:139794124chr1:223946971ENST00000359662+311124_18089554.0Zinc fingerTRAF-type 1
HgeneTRAF2chr9:139794124chr1:223946971ENST00000359662+311177_23389554.0Zinc fingerTRAF-type 2
HgeneTRAF2chr9:139794124chr1:223946971ENST00000536468+412124_18089502.0Zinc fingerTRAF-type 1
HgeneTRAF2chr9:139794124chr1:223946971ENST00000536468+412177_23389502.0Zinc fingerTRAF-type 2
TgeneCAPN2chr9:139794124chr1:223946971ENST00000295006102145_344439701.0DomainCalpain catalytic
TgeneCAPN2chr9:139794124chr1:223946971ENST00000433674102145_344361623.0DomainCalpain catalytic
TgeneCAPN2chr9:139794124chr1:223946971ENST000002950061021345_514439701.0RegionNote=Domain III
TgeneCAPN2chr9:139794124chr1:223946971ENST000004336741021345_514361623.0RegionNote=Domain III


Top

Fusion Gene Sequence for TRAF2-CAPN2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>93644_93644_1_TRAF2-CAPN2_TRAF2_chr9_139794124_ENST00000247668_CAPN2_chr1_223946971_ENST00000295006_length(transcript)=2266nt_BP=319nt
TTCCGGGCGCGCTGCGACCGTTGGGGCTTTGTTCGCGGGGGTCACAGCTCTCATGGCTGCAGCTAGCGTGACCCCCCCTGGCTCCCTGGA
GTTGCTACAGCCCGGCTTCTCCAAGACCCTCCTGGGGACCAAGCTGGAAGCCAAGTACCTGTGCTCCGCCTGCAGAAACGTCCTCCGCAG
GCCCTTCCAGGCGCAGTGTGGCCACCGGTACTGCTCCTTCTGCCTGGCCAGCATCCTCAGCTCTGGGCCTCAGAACTGTGCTGCCTGTGT
TCACGAGGGCATATATGAAGAAGGCATTTCTATTTTAGAAAGCAGTTCGTTAAGTGGGCAGACCAACATCCACCTCAGCAAAAACTTCTT
CCTGACGAATCGCGCCAGGGAGCGCTCAGACACCTTCATCAACCTCCGGGAGGTGCTCAACCGCTTCAAGCTGCCGCCAGGAGAGTACAT
TCTCGTGCCTTCCACCTTCGAACCCAACAAGGATGGGGATTTCTGCATCCGGGTCTTTTCTGAAAAGAAAGCTGACTACCAAGCTGTCGA
TGATGAAATCGAGGCCAATCTTGAAGAGTTCGACATCAGCGAGGATGACATTGATGATGGATTCAGGAGACTGTTTGCCCAGTTGGCAGG
AGAGGATGCGGAGATCTCTGCCTTTGAGCTGCAGACCATCCTGAGAAGGGTTCTAGCAAAGCGCCAAGATATCAAGTCAGATGGCTTCAG
CATCGAGACATGCAAAATTATGGTTGACATGCTAGATTCGGACGGGAGTGGCAAGCTGGGGCTGAAGGAGTTCTACATTCTCTGGACGAA
GATTCAAAAATACCAAAAAATTTACCGAGAAATCGACGTTGACAGGTCTGGTACCATGAATTCCTATGAAATGCGGAAGGCATTAGAAGA
AGCAGGTTTCAAGATGCCCTGTCAACTCCACCAAGTCATCGTTGCTCGGTTTGCAGATGACCAGCTCATCATCGATTTTGATAATTTTGT
TCGGTGTTTGGTTCGGCTGGAAACGCTATTCAAGATATTTAAGCAGCTGGATCCCGAGAATACTGGAACAATAGAGCTCGACCTTATCTC
TTGGCTCTGTTTCTCAGTACTTTGAAGTTATAACTAATCTGCCTGAAGACTTCTCATGATGGAAAATCAGCCAAGGACTAAGCTTCCATA
GAAATACACTTTGTATCTGGACCTCAAAATTATGGGAACATTTACTTAAACGGATGATCATAGCTGAAAATAATGATACTGTCAATTTGA
GATAGCAGAAGTTTCACACATCAAAGTAAAAGATTTGCATATCATTATACTAAATGCAAATGAGTCGCTTAACCCTTGACAAGGTCAAAG
AAAGCTTTAAATCTGTAAATAGTATACACTTTTTACTTTTACACACTTTCCTGTTCATAGCAATATTAAATCAGGAAAAAAAAATGCAGG
GAGGTATTTAACAGCTGAGCAAAAACATTGAGTCGCTCTCAAAGGACACGAGGCCCTTGGCAGGGAATATTTAAAGCAACTTCAAGTTTA
AAATGCAGCTGTTGATTCTACCAAACAACAGTCCAAGATTACCATTTCCCATGAGCCAACTGGGAAACATGGTATATCATGAAGTAATCT
TGTCAAGGCATCTGGAGAGTCCAGGAGAGAAGACTCACCTCTGTCGCTTGGGTTAAACAAGAGACAGGTTTTGTAGAATATTGATTGGTA
ATAGTAAATCGTTCTCCTTACAATCAAGTTCTTGACCCTATTCGGCCTTATACATCTGGTCTTACAAAGACCAAAGGGATCCTGCGCTTG
ATCAACTGAACCAGTATGCCAAAACCAGGCATCCAATTTGTAAACCAATTATGATAAAGGACAAAATAAGCTGTTTGCCACCTCAAAACT
TTATGAACTTCACCACCACTAGTGTCTGTCCATGGAGTTAGAGGGGACATCACTTAGAAGTTCTTATAGAAAGGACACAAGTTTGTTTCC
TGGCTTTACCTTGGGAAAATGCTAGCAACATTATAGAAATTTTGCCTTGTTGCCTTATCTTCTTCCAAATGTACTGTTAAATAAAAATAA
AGGGTTACCCCATGCAATCACACCATGCCATGTTTTCCTTCCTGGAGGGCAGCCCCACAGGACGGTTTATGAGCACACAATTATAGCTTG
TTTCTACTTTAACAAGGTATGCTGCCTCTGTAAATTCATGTATTCAAAGGAAAAGACACCTTGCCTATAATTAAAATGTGGAACTATAAA

>93644_93644_1_TRAF2-CAPN2_TRAF2_chr9_139794124_ENST00000247668_CAPN2_chr1_223946971_ENST00000295006_length(amino acids)=358AA_BP=97
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSLSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEE
FDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYR

--------------------------------------------------------------
>93644_93644_2_TRAF2-CAPN2_TRAF2_chr9_139794124_ENST00000247668_CAPN2_chr1_223946971_ENST00000433674_length(transcript)=2264nt_BP=319nt
TTCCGGGCGCGCTGCGACCGTTGGGGCTTTGTTCGCGGGGGTCACAGCTCTCATGGCTGCAGCTAGCGTGACCCCCCCTGGCTCCCTGGA
GTTGCTACAGCCCGGCTTCTCCAAGACCCTCCTGGGGACCAAGCTGGAAGCCAAGTACCTGTGCTCCGCCTGCAGAAACGTCCTCCGCAG
GCCCTTCCAGGCGCAGTGTGGCCACCGGTACTGCTCCTTCTGCCTGGCCAGCATCCTCAGCTCTGGGCCTCAGAACTGTGCTGCCTGTGT
TCACGAGGGCATATATGAAGAAGGCATTTCTATTTTAGAAAGCAGTTCGTTAAGTGGGCAGACCAACATCCACCTCAGCAAAAACTTCTT
CCTGACGAATCGCGCCAGGGAGCGCTCAGACACCTTCATCAACCTCCGGGAGGTGCTCAACCGCTTCAAGCTGCCGCCAGGAGAGTACAT
TCTCGTGCCTTCCACCTTCGAACCCAACAAGGATGGGGATTTCTGCATCCGGGTCTTTTCTGAAAAGAAAGCTGACTACCAAGCTGTCGA
TGATGAAATCGAGGCCAATCTTGAAGAGTTCGACATCAGCGAGGATGACATTGATGATGGATTCAGGAGACTGTTTGCCCAGTTGGCAGG
AGAGGATGCGGAGATCTCTGCCTTTGAGCTGCAGACCATCCTGAGAAGGGTTCTAGCAAAGCGCCAAGATATCAAGTCAGATGGCTTCAG
CATCGAGACATGCAAAATTATGGTTGACATGCTAGATTCGGACGGGAGTGGCAAGCTGGGGCTGAAGGAGTTCTACATTCTCTGGACGAA
GATTCAAAAATACCAAAAAATTTACCGAGAAATCGACGTTGACAGGTCTGGTACCATGAATTCCTATGAAATGCGGAAGGCATTAGAAGA
AGCAGGTTTCAAGATGCCCTGTCAACTCCACCAAGTCATCGTTGCTCGGTTTGCAGATGACCAGCTCATCATCGATTTTGATAATTTTGT
TCGGTGTTTGGTTCGGCTGGAAACGCTATTCAAGATATTTAAGCAGCTGGATCCCGAGAATACTGGAACAATAGAGCTCGACCTTATCTC
TTGGCTCTGTTTCTCAGTACTTTGAAGTTATAACTAATCTGCCTGAAGACTTCTCATGATGGAAAATCAGCCAAGGACTAAGCTTCCATA
GAAATACACTTTGTATCTGGACCTCAAAATTATGGGAACATTTACTTAAACGGATGATCATAGCTGAAAATAATGATACTGTCAATTTGA
GATAGCAGAAGTTTCACACATCAAAGTAAAAGATTTGCATATCATTATACTAAATGCAAATGAGTCGCTTAACCCTTGACAAGGTCAAAG
AAAGCTTTAAATCTGTAAATAGTATACACTTTTTACTTTTACACACTTTCCTGTTCATAGCAATATTAAATCAGGAAAAAAAAATGCAGG
GAGGTATTTAACAGCTGAGCAAAAACATTGAGTCGCTCTCAAAGGACACGAGGCCCTTGGCAGGGAATATTTAAAGCAACTTCAAGTTTA
AAATGCAGCTGTTGATTCTACCAAACAACAGTCCAAGATTACCATTTCCCATGAGCCAACTGGGAAACATGGTATATCATGAAGTAATCT
TGTCAAGGCATCTGGAGAGTCCAGGAGAGAAGACTCACCTCTGTCGCTTGGGTTAAACAAGAGACAGGTTTTGTAGAATATTGATTGGTA
ATAGTAAATCGTTCTCCTTACAATCAAGTTCTTGACCCTATTCGGCCTTATACATCTGGTCTTACAAAGACCAAAGGGATCCTGCGCTTG
ATCAACTGAACCAGTATGCCAAAACCAGGCATCCAATTTGTAAACCAATTATGATAAAGGACAAAATAAGCTGTTTGCCACCTCAAAACT
TTATGAACTTCACCACCACTAGTGTCTGTCCATGGAGTTAGAGGGGACATCACTTAGAAGTTCTTATAGAAAGGACACAAGTTTGTTTCC
TGGCTTTACCTTGGGAAAATGCTAGCAACATTATAGAAATTTTGCCTTGTTGCCTTATCTTCTTCCAAATGTACTGTTAAATAAAAATAA
AGGGTTACCCCATGCAATCACACCATGCCATGTTTTCCTTCCTGGAGGGCAGCCCCACAGGACGGTTTATGAGCACACAATTATAGCTTG
TTTCTACTTTAACAAGGTATGCTGCCTCTGTAAATTCATGTATTCAAAGGAAAAGACACCTTGCCTATAATTAAAATGTGGAACTATAAA

>93644_93644_2_TRAF2-CAPN2_TRAF2_chr9_139794124_ENST00000247668_CAPN2_chr1_223946971_ENST00000433674_length(amino acids)=358AA_BP=97
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSLSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEE
FDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYR

--------------------------------------------------------------
>93644_93644_3_TRAF2-CAPN2_TRAF2_chr9_139794124_ENST00000359662_CAPN2_chr1_223946971_ENST00000295006_length(transcript)=2259nt_BP=312nt
CGCGCTGCGACCGTTGGGGCTTTGTTCGCGGGGGTCACAGCTCTCATGGCTGCAGCTAGCGTGACCCCCCCTGGCTCCCTGGAGTTGCTA
CAGCCCGGCTTCTCCAAGACCCTCCTGGGGACCAAGCTGGAAGCCAAGTACCTGTGCTCCGCCTGCAGAAACGTCCTCCGCAGGCCCTTC
CAGGCGCAGTGTGGCCACCGGTACTGCTCCTTCTGCCTGGCCAGCATCCTCAGCTCTGGGCCTCAGAACTGTGCTGCCTGTGTTCACGAG
GGCATATATGAAGAAGGCATTTCTATTTTAGAAAGCAGTTCGTTAAGTGGGCAGACCAACATCCACCTCAGCAAAAACTTCTTCCTGACG
AATCGCGCCAGGGAGCGCTCAGACACCTTCATCAACCTCCGGGAGGTGCTCAACCGCTTCAAGCTGCCGCCAGGAGAGTACATTCTCGTG
CCTTCCACCTTCGAACCCAACAAGGATGGGGATTTCTGCATCCGGGTCTTTTCTGAAAAGAAAGCTGACTACCAAGCTGTCGATGATGAA
ATCGAGGCCAATCTTGAAGAGTTCGACATCAGCGAGGATGACATTGATGATGGATTCAGGAGACTGTTTGCCCAGTTGGCAGGAGAGGAT
GCGGAGATCTCTGCCTTTGAGCTGCAGACCATCCTGAGAAGGGTTCTAGCAAAGCGCCAAGATATCAAGTCAGATGGCTTCAGCATCGAG
ACATGCAAAATTATGGTTGACATGCTAGATTCGGACGGGAGTGGCAAGCTGGGGCTGAAGGAGTTCTACATTCTCTGGACGAAGATTCAA
AAATACCAAAAAATTTACCGAGAAATCGACGTTGACAGGTCTGGTACCATGAATTCCTATGAAATGCGGAAGGCATTAGAAGAAGCAGGT
TTCAAGATGCCCTGTCAACTCCACCAAGTCATCGTTGCTCGGTTTGCAGATGACCAGCTCATCATCGATTTTGATAATTTTGTTCGGTGT
TTGGTTCGGCTGGAAACGCTATTCAAGATATTTAAGCAGCTGGATCCCGAGAATACTGGAACAATAGAGCTCGACCTTATCTCTTGGCTC
TGTTTCTCAGTACTTTGAAGTTATAACTAATCTGCCTGAAGACTTCTCATGATGGAAAATCAGCCAAGGACTAAGCTTCCATAGAAATAC
ACTTTGTATCTGGACCTCAAAATTATGGGAACATTTACTTAAACGGATGATCATAGCTGAAAATAATGATACTGTCAATTTGAGATAGCA
GAAGTTTCACACATCAAAGTAAAAGATTTGCATATCATTATACTAAATGCAAATGAGTCGCTTAACCCTTGACAAGGTCAAAGAAAGCTT
TAAATCTGTAAATAGTATACACTTTTTACTTTTACACACTTTCCTGTTCATAGCAATATTAAATCAGGAAAAAAAAATGCAGGGAGGTAT
TTAACAGCTGAGCAAAAACATTGAGTCGCTCTCAAAGGACACGAGGCCCTTGGCAGGGAATATTTAAAGCAACTTCAAGTTTAAAATGCA
GCTGTTGATTCTACCAAACAACAGTCCAAGATTACCATTTCCCATGAGCCAACTGGGAAACATGGTATATCATGAAGTAATCTTGTCAAG
GCATCTGGAGAGTCCAGGAGAGAAGACTCACCTCTGTCGCTTGGGTTAAACAAGAGACAGGTTTTGTAGAATATTGATTGGTAATAGTAA
ATCGTTCTCCTTACAATCAAGTTCTTGACCCTATTCGGCCTTATACATCTGGTCTTACAAAGACCAAAGGGATCCTGCGCTTGATCAACT
GAACCAGTATGCCAAAACCAGGCATCCAATTTGTAAACCAATTATGATAAAGGACAAAATAAGCTGTTTGCCACCTCAAAACTTTATGAA
CTTCACCACCACTAGTGTCTGTCCATGGAGTTAGAGGGGACATCACTTAGAAGTTCTTATAGAAAGGACACAAGTTTGTTTCCTGGCTTT
ACCTTGGGAAAATGCTAGCAACATTATAGAAATTTTGCCTTGTTGCCTTATCTTCTTCCAAATGTACTGTTAAATAAAAATAAAGGGTTA
CCCCATGCAATCACACCATGCCATGTTTTCCTTCCTGGAGGGCAGCCCCACAGGACGGTTTATGAGCACACAATTATAGCTTGTTTCTAC
TTTAACAAGGTATGCTGCCTCTGTAAATTCATGTATTCAAAGGAAAAGACACCTTGCCTATAATTAAAATGTGGAACTATAAAATTTTTT

>93644_93644_3_TRAF2-CAPN2_TRAF2_chr9_139794124_ENST00000359662_CAPN2_chr1_223946971_ENST00000295006_length(amino acids)=358AA_BP=97
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSLSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEE
FDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYR

--------------------------------------------------------------
>93644_93644_4_TRAF2-CAPN2_TRAF2_chr9_139794124_ENST00000359662_CAPN2_chr1_223946971_ENST00000433674_length(transcript)=2257nt_BP=312nt
CGCGCTGCGACCGTTGGGGCTTTGTTCGCGGGGGTCACAGCTCTCATGGCTGCAGCTAGCGTGACCCCCCCTGGCTCCCTGGAGTTGCTA
CAGCCCGGCTTCTCCAAGACCCTCCTGGGGACCAAGCTGGAAGCCAAGTACCTGTGCTCCGCCTGCAGAAACGTCCTCCGCAGGCCCTTC
CAGGCGCAGTGTGGCCACCGGTACTGCTCCTTCTGCCTGGCCAGCATCCTCAGCTCTGGGCCTCAGAACTGTGCTGCCTGTGTTCACGAG
GGCATATATGAAGAAGGCATTTCTATTTTAGAAAGCAGTTCGTTAAGTGGGCAGACCAACATCCACCTCAGCAAAAACTTCTTCCTGACG
AATCGCGCCAGGGAGCGCTCAGACACCTTCATCAACCTCCGGGAGGTGCTCAACCGCTTCAAGCTGCCGCCAGGAGAGTACATTCTCGTG
CCTTCCACCTTCGAACCCAACAAGGATGGGGATTTCTGCATCCGGGTCTTTTCTGAAAAGAAAGCTGACTACCAAGCTGTCGATGATGAA
ATCGAGGCCAATCTTGAAGAGTTCGACATCAGCGAGGATGACATTGATGATGGATTCAGGAGACTGTTTGCCCAGTTGGCAGGAGAGGAT
GCGGAGATCTCTGCCTTTGAGCTGCAGACCATCCTGAGAAGGGTTCTAGCAAAGCGCCAAGATATCAAGTCAGATGGCTTCAGCATCGAG
ACATGCAAAATTATGGTTGACATGCTAGATTCGGACGGGAGTGGCAAGCTGGGGCTGAAGGAGTTCTACATTCTCTGGACGAAGATTCAA
AAATACCAAAAAATTTACCGAGAAATCGACGTTGACAGGTCTGGTACCATGAATTCCTATGAAATGCGGAAGGCATTAGAAGAAGCAGGT
TTCAAGATGCCCTGTCAACTCCACCAAGTCATCGTTGCTCGGTTTGCAGATGACCAGCTCATCATCGATTTTGATAATTTTGTTCGGTGT
TTGGTTCGGCTGGAAACGCTATTCAAGATATTTAAGCAGCTGGATCCCGAGAATACTGGAACAATAGAGCTCGACCTTATCTCTTGGCTC
TGTTTCTCAGTACTTTGAAGTTATAACTAATCTGCCTGAAGACTTCTCATGATGGAAAATCAGCCAAGGACTAAGCTTCCATAGAAATAC
ACTTTGTATCTGGACCTCAAAATTATGGGAACATTTACTTAAACGGATGATCATAGCTGAAAATAATGATACTGTCAATTTGAGATAGCA
GAAGTTTCACACATCAAAGTAAAAGATTTGCATATCATTATACTAAATGCAAATGAGTCGCTTAACCCTTGACAAGGTCAAAGAAAGCTT
TAAATCTGTAAATAGTATACACTTTTTACTTTTACACACTTTCCTGTTCATAGCAATATTAAATCAGGAAAAAAAAATGCAGGGAGGTAT
TTAACAGCTGAGCAAAAACATTGAGTCGCTCTCAAAGGACACGAGGCCCTTGGCAGGGAATATTTAAAGCAACTTCAAGTTTAAAATGCA
GCTGTTGATTCTACCAAACAACAGTCCAAGATTACCATTTCCCATGAGCCAACTGGGAAACATGGTATATCATGAAGTAATCTTGTCAAG
GCATCTGGAGAGTCCAGGAGAGAAGACTCACCTCTGTCGCTTGGGTTAAACAAGAGACAGGTTTTGTAGAATATTGATTGGTAATAGTAA
ATCGTTCTCCTTACAATCAAGTTCTTGACCCTATTCGGCCTTATACATCTGGTCTTACAAAGACCAAAGGGATCCTGCGCTTGATCAACT
GAACCAGTATGCCAAAACCAGGCATCCAATTTGTAAACCAATTATGATAAAGGACAAAATAAGCTGTTTGCCACCTCAAAACTTTATGAA
CTTCACCACCACTAGTGTCTGTCCATGGAGTTAGAGGGGACATCACTTAGAAGTTCTTATAGAAAGGACACAAGTTTGTTTCCTGGCTTT
ACCTTGGGAAAATGCTAGCAACATTATAGAAATTTTGCCTTGTTGCCTTATCTTCTTCCAAATGTACTGTTAAATAAAAATAAAGGGTTA
CCCCATGCAATCACACCATGCCATGTTTTCCTTCCTGGAGGGCAGCCCCACAGGACGGTTTATGAGCACACAATTATAGCTTGTTTCTAC
TTTAACAAGGTATGCTGCCTCTGTAAATTCATGTATTCAAAGGAAAAGACACCTTGCCTATAATTAAAATGTGGAACTATAAAATTTTTT

>93644_93644_4_TRAF2-CAPN2_TRAF2_chr9_139794124_ENST00000359662_CAPN2_chr1_223946971_ENST00000433674_length(amino acids)=358AA_BP=97
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSLSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEE
FDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYR

--------------------------------------------------------------
>93644_93644_5_TRAF2-CAPN2_TRAF2_chr9_139794124_ENST00000536468_CAPN2_chr1_223946971_ENST00000295006_length(transcript)=2387nt_BP=440nt
GAAACCAGCTTCCCTCGGAGGCTGCAGCACAGGGCTGACATGCAAACGTCTGAAAAAGAGGCAAGCTCTCGGTGTGAGCAAGTGGACTGC
GGCTATTTGAGGAAGGAGCCCACGTGGGAATCCCCTGAGCTGCGCCATGGCCAGAGGCTTTGTTCGCGGGGGTCACAGCTCTCATGGCTG
CAGCTAGCGTGACCCCCCCTGGCTCCCTGGAGTTGCTACAGCCCGGCTTCTCCAAGACCCTCCTGGGGACCAAGCTGGAAGCCAAGTACC
TGTGCTCCGCCTGCAGAAACGTCCTCCGCAGGCCCTTCCAGGCGCAGTGTGGCCACCGGTACTGCTCCTTCTGCCTGGCCAGCATCCTCA
GCTCTGGGCCTCAGAACTGTGCTGCCTGTGTTCACGAGGGCATATATGAAGAAGGCATTTCTATTTTAGAAAGCAGTTCGTTAAGTGGGC
AGACCAACATCCACCTCAGCAAAAACTTCTTCCTGACGAATCGCGCCAGGGAGCGCTCAGACACCTTCATCAACCTCCGGGAGGTGCTCA
ACCGCTTCAAGCTGCCGCCAGGAGAGTACATTCTCGTGCCTTCCACCTTCGAACCCAACAAGGATGGGGATTTCTGCATCCGGGTCTTTT
CTGAAAAGAAAGCTGACTACCAAGCTGTCGATGATGAAATCGAGGCCAATCTTGAAGAGTTCGACATCAGCGAGGATGACATTGATGATG
GATTCAGGAGACTGTTTGCCCAGTTGGCAGGAGAGGATGCGGAGATCTCTGCCTTTGAGCTGCAGACCATCCTGAGAAGGGTTCTAGCAA
AGCGCCAAGATATCAAGTCAGATGGCTTCAGCATCGAGACATGCAAAATTATGGTTGACATGCTAGATTCGGACGGGAGTGGCAAGCTGG
GGCTGAAGGAGTTCTACATTCTCTGGACGAAGATTCAAAAATACCAAAAAATTTACCGAGAAATCGACGTTGACAGGTCTGGTACCATGA
ATTCCTATGAAATGCGGAAGGCATTAGAAGAAGCAGGTTTCAAGATGCCCTGTCAACTCCACCAAGTCATCGTTGCTCGGTTTGCAGATG
ACCAGCTCATCATCGATTTTGATAATTTTGTTCGGTGTTTGGTTCGGCTGGAAACGCTATTCAAGATATTTAAGCAGCTGGATCCCGAGA
ATACTGGAACAATAGAGCTCGACCTTATCTCTTGGCTCTGTTTCTCAGTACTTTGAAGTTATAACTAATCTGCCTGAAGACTTCTCATGA
TGGAAAATCAGCCAAGGACTAAGCTTCCATAGAAATACACTTTGTATCTGGACCTCAAAATTATGGGAACATTTACTTAAACGGATGATC
ATAGCTGAAAATAATGATACTGTCAATTTGAGATAGCAGAAGTTTCACACATCAAAGTAAAAGATTTGCATATCATTATACTAAATGCAA
ATGAGTCGCTTAACCCTTGACAAGGTCAAAGAAAGCTTTAAATCTGTAAATAGTATACACTTTTTACTTTTACACACTTTCCTGTTCATA
GCAATATTAAATCAGGAAAAAAAAATGCAGGGAGGTATTTAACAGCTGAGCAAAAACATTGAGTCGCTCTCAAAGGACACGAGGCCCTTG
GCAGGGAATATTTAAAGCAACTTCAAGTTTAAAATGCAGCTGTTGATTCTACCAAACAACAGTCCAAGATTACCATTTCCCATGAGCCAA
CTGGGAAACATGGTATATCATGAAGTAATCTTGTCAAGGCATCTGGAGAGTCCAGGAGAGAAGACTCACCTCTGTCGCTTGGGTTAAACA
AGAGACAGGTTTTGTAGAATATTGATTGGTAATAGTAAATCGTTCTCCTTACAATCAAGTTCTTGACCCTATTCGGCCTTATACATCTGG
TCTTACAAAGACCAAAGGGATCCTGCGCTTGATCAACTGAACCAGTATGCCAAAACCAGGCATCCAATTTGTAAACCAATTATGATAAAG
GACAAAATAAGCTGTTTGCCACCTCAAAACTTTATGAACTTCACCACCACTAGTGTCTGTCCATGGAGTTAGAGGGGACATCACTTAGAA
GTTCTTATAGAAAGGACACAAGTTTGTTTCCTGGCTTTACCTTGGGAAAATGCTAGCAACATTATAGAAATTTTGCCTTGTTGCCTTATC
TTCTTCCAAATGTACTGTTAAATAAAAATAAAGGGTTACCCCATGCAATCACACCATGCCATGTTTTCCTTCCTGGAGGGCAGCCCCACA
GGACGGTTTATGAGCACACAATTATAGCTTGTTTCTACTTTAACAAGGTATGCTGCCTCTGTAAATTCATGTATTCAAAGGAAAAGACAC

>93644_93644_5_TRAF2-CAPN2_TRAF2_chr9_139794124_ENST00000536468_CAPN2_chr1_223946971_ENST00000295006_length(amino acids)=358AA_BP=97
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSLSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEE
FDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYR

--------------------------------------------------------------
>93644_93644_6_TRAF2-CAPN2_TRAF2_chr9_139794124_ENST00000536468_CAPN2_chr1_223946971_ENST00000433674_length(transcript)=2385nt_BP=440nt
GAAACCAGCTTCCCTCGGAGGCTGCAGCACAGGGCTGACATGCAAACGTCTGAAAAAGAGGCAAGCTCTCGGTGTGAGCAAGTGGACTGC
GGCTATTTGAGGAAGGAGCCCACGTGGGAATCCCCTGAGCTGCGCCATGGCCAGAGGCTTTGTTCGCGGGGGTCACAGCTCTCATGGCTG
CAGCTAGCGTGACCCCCCCTGGCTCCCTGGAGTTGCTACAGCCCGGCTTCTCCAAGACCCTCCTGGGGACCAAGCTGGAAGCCAAGTACC
TGTGCTCCGCCTGCAGAAACGTCCTCCGCAGGCCCTTCCAGGCGCAGTGTGGCCACCGGTACTGCTCCTTCTGCCTGGCCAGCATCCTCA
GCTCTGGGCCTCAGAACTGTGCTGCCTGTGTTCACGAGGGCATATATGAAGAAGGCATTTCTATTTTAGAAAGCAGTTCGTTAAGTGGGC
AGACCAACATCCACCTCAGCAAAAACTTCTTCCTGACGAATCGCGCCAGGGAGCGCTCAGACACCTTCATCAACCTCCGGGAGGTGCTCA
ACCGCTTCAAGCTGCCGCCAGGAGAGTACATTCTCGTGCCTTCCACCTTCGAACCCAACAAGGATGGGGATTTCTGCATCCGGGTCTTTT
CTGAAAAGAAAGCTGACTACCAAGCTGTCGATGATGAAATCGAGGCCAATCTTGAAGAGTTCGACATCAGCGAGGATGACATTGATGATG
GATTCAGGAGACTGTTTGCCCAGTTGGCAGGAGAGGATGCGGAGATCTCTGCCTTTGAGCTGCAGACCATCCTGAGAAGGGTTCTAGCAA
AGCGCCAAGATATCAAGTCAGATGGCTTCAGCATCGAGACATGCAAAATTATGGTTGACATGCTAGATTCGGACGGGAGTGGCAAGCTGG
GGCTGAAGGAGTTCTACATTCTCTGGACGAAGATTCAAAAATACCAAAAAATTTACCGAGAAATCGACGTTGACAGGTCTGGTACCATGA
ATTCCTATGAAATGCGGAAGGCATTAGAAGAAGCAGGTTTCAAGATGCCCTGTCAACTCCACCAAGTCATCGTTGCTCGGTTTGCAGATG
ACCAGCTCATCATCGATTTTGATAATTTTGTTCGGTGTTTGGTTCGGCTGGAAACGCTATTCAAGATATTTAAGCAGCTGGATCCCGAGA
ATACTGGAACAATAGAGCTCGACCTTATCTCTTGGCTCTGTTTCTCAGTACTTTGAAGTTATAACTAATCTGCCTGAAGACTTCTCATGA
TGGAAAATCAGCCAAGGACTAAGCTTCCATAGAAATACACTTTGTATCTGGACCTCAAAATTATGGGAACATTTACTTAAACGGATGATC
ATAGCTGAAAATAATGATACTGTCAATTTGAGATAGCAGAAGTTTCACACATCAAAGTAAAAGATTTGCATATCATTATACTAAATGCAA
ATGAGTCGCTTAACCCTTGACAAGGTCAAAGAAAGCTTTAAATCTGTAAATAGTATACACTTTTTACTTTTACACACTTTCCTGTTCATA
GCAATATTAAATCAGGAAAAAAAAATGCAGGGAGGTATTTAACAGCTGAGCAAAAACATTGAGTCGCTCTCAAAGGACACGAGGCCCTTG
GCAGGGAATATTTAAAGCAACTTCAAGTTTAAAATGCAGCTGTTGATTCTACCAAACAACAGTCCAAGATTACCATTTCCCATGAGCCAA
CTGGGAAACATGGTATATCATGAAGTAATCTTGTCAAGGCATCTGGAGAGTCCAGGAGAGAAGACTCACCTCTGTCGCTTGGGTTAAACA
AGAGACAGGTTTTGTAGAATATTGATTGGTAATAGTAAATCGTTCTCCTTACAATCAAGTTCTTGACCCTATTCGGCCTTATACATCTGG
TCTTACAAAGACCAAAGGGATCCTGCGCTTGATCAACTGAACCAGTATGCCAAAACCAGGCATCCAATTTGTAAACCAATTATGATAAAG
GACAAAATAAGCTGTTTGCCACCTCAAAACTTTATGAACTTCACCACCACTAGTGTCTGTCCATGGAGTTAGAGGGGACATCACTTAGAA
GTTCTTATAGAAAGGACACAAGTTTGTTTCCTGGCTTTACCTTGGGAAAATGCTAGCAACATTATAGAAATTTTGCCTTGTTGCCTTATC
TTCTTCCAAATGTACTGTTAAATAAAAATAAAGGGTTACCCCATGCAATCACACCATGCCATGTTTTCCTTCCTGGAGGGCAGCCCCACA
GGACGGTTTATGAGCACACAATTATAGCTTGTTTCTACTTTAACAAGGTATGCTGCCTCTGTAAATTCATGTATTCAAAGGAAAAGACAC

>93644_93644_6_TRAF2-CAPN2_TRAF2_chr9_139794124_ENST00000536468_CAPN2_chr1_223946971_ENST00000433674_length(amino acids)=358AA_BP=97
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSLSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEE
FDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYR

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for TRAF2-CAPN2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for TRAF2-CAPN2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for TRAF2-CAPN2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource