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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TRAK2-AP1S3 (FusionGDB2 ID:93720)

Fusion Gene Summary for TRAK2-AP1S3

check button Fusion gene summary
Fusion gene informationFusion gene name: TRAK2-AP1S3
Fusion gene ID: 93720
HgeneTgene
Gene symbol

TRAK2

AP1S3

Gene ID

66008

130340

Gene nametrafficking kinesin protein 2adaptor related protein complex 1 subunit sigma 3
SynonymsALS2CR3|CALS-C|GRIF-1|GRIF1|MILT2|OIP98PSORS15
Cytomap

2q33.1

2q36.1

Type of geneprotein-codingprotein-coding
Descriptiontrafficking kinesin-binding protein 2O-linked N-acetylglucosamine transferase interacting protein 98amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 proteingamAP-1 complex subunit sigma-3adapter-related protein complex 1 subunit sigma-1Cadaptor protein complex AP-1 sigma-1C subunitadaptor related protein complex 1 sigma 3 subunitadaptor-related protein complex 1 subunit sigma-1Cclathrin assembly protein co
Modification date2020031320200313
UniProtAcc.

Q96PC3

Ensembl transtripts involved in fusion geneENST00000451703, ENST00000332624, 
ENST00000430254, 		ENST00000396653, 
ENST00000396654, ENST00000409375, 
ENST00000423110, ENST00000443700, 
ENST00000446015, 
Fusion gene scores* DoF score6 X 6 X 3=1084 X 2 X 3=24
# samples 75
** MAII scorelog2(7/108*10)=-0.625604485218502
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/24*10)=1.05889368905357
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: TRAK2 [Title/Abstract] AND AP1S3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTRAK2(202285140)-AP1S3(224642586), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across TRAK2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across AP1S3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A48K-01ATRAK2chr2

202285140

-AP1S3chr2

224642586

-
ChimerDB4SARCTCGA-DX-AATS-01ATRAK2chr2

202285140

-AP1S3chr2

224642586

-


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Fusion Gene ORF analysis for TRAK2-AP1S3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000451703ENST00000396653TRAK2chr2

202285140

-AP1S3chr2

224642586

-
5UTR-3CDSENST00000451703ENST00000396654TRAK2chr2

202285140

-AP1S3chr2

224642586

-
5UTR-3CDSENST00000451703ENST00000409375TRAK2chr2

202285140

-AP1S3chr2

224642586

-
5UTR-3CDSENST00000451703ENST00000423110TRAK2chr2

202285140

-AP1S3chr2

224642586

-
5UTR-3CDSENST00000451703ENST00000443700TRAK2chr2

202285140

-AP1S3chr2

224642586

-
5UTR-3CDSENST00000451703ENST00000446015TRAK2chr2

202285140

-AP1S3chr2

224642586

-
In-frameENST00000332624ENST00000396653TRAK2chr2

202285140

-AP1S3chr2

224642586

-
In-frameENST00000332624ENST00000396654TRAK2chr2

202285140

-AP1S3chr2

224642586

-
In-frameENST00000332624ENST00000409375TRAK2chr2

202285140

-AP1S3chr2

224642586

-
In-frameENST00000332624ENST00000423110TRAK2chr2

202285140

-AP1S3chr2

224642586

-
In-frameENST00000332624ENST00000443700TRAK2chr2

202285140

-AP1S3chr2

224642586

-
In-frameENST00000332624ENST00000446015TRAK2chr2

202285140

-AP1S3chr2

224642586

-
In-frameENST00000430254ENST00000396653TRAK2chr2

202285140

-AP1S3chr2

224642586

-
In-frameENST00000430254ENST00000396654TRAK2chr2

202285140

-AP1S3chr2

224642586

-
In-frameENST00000430254ENST00000409375TRAK2chr2

202285140

-AP1S3chr2

224642586

-
In-frameENST00000430254ENST00000423110TRAK2chr2

202285140

-AP1S3chr2

224642586

-
In-frameENST00000430254ENST00000443700TRAK2chr2

202285140

-AP1S3chr2

224642586

-
In-frameENST00000430254ENST00000446015TRAK2chr2

202285140

-AP1S3chr2

224642586

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000332624TRAK2chr2202285140-ENST00000443700AP1S3chr2224642586-21505205171011164
ENST00000332624TRAK2chr2202285140-ENST00000396654AP1S3chr2224642586-1215520517981154
ENST00000332624TRAK2chr2202285140-ENST00000396653AP1S3chr2224642586-974520244281
ENST00000332624TRAK2chr2202285140-ENST00000446015AP1S3chr2224642586-982520517981155
ENST00000332624TRAK2chr2202285140-ENST00000409375AP1S3chr2224642586-978520517930137
ENST00000332624TRAK2chr2202285140-ENST00000423110AP1S3chr2224642586-832520517831105
ENST00000430254TRAK2chr2202285140-ENST00000443700AP1S3chr2224642586-2071441438932164
ENST00000430254TRAK2chr2202285140-ENST00000396654AP1S3chr2224642586-1136441438902154
ENST00000430254TRAK2chr2202285140-ENST00000396653AP1S3chr2224642586-89544129951170
ENST00000430254TRAK2chr2202285140-ENST00000446015AP1S3chr2224642586-903441438902154
ENST00000430254TRAK2chr2202285140-ENST00000409375AP1S3chr2224642586-899441438851137
ENST00000430254TRAK2chr2202285140-ENST00000423110AP1S3chr2224642586-753441438752104

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000332624ENST00000443700TRAK2chr2202285140-AP1S3chr2224642586-0.84674690.15325306
ENST00000332624ENST00000396654TRAK2chr2202285140-AP1S3chr2224642586-0.464530920.5354691
ENST00000332624ENST00000396653TRAK2chr2202285140-AP1S3chr2224642586-0.65037780.34962225
ENST00000332624ENST00000446015TRAK2chr2202285140-AP1S3chr2224642586-0.47284040.5271596
ENST00000332624ENST00000409375TRAK2chr2202285140-AP1S3chr2224642586-0.454469560.5455304
ENST00000332624ENST00000423110TRAK2chr2202285140-AP1S3chr2224642586-0.358895150.6411048
ENST00000430254ENST00000443700TRAK2chr2202285140-AP1S3chr2224642586-0.776171150.22382884
ENST00000430254ENST00000396654TRAK2chr2202285140-AP1S3chr2224642586-0.328717980.671282
ENST00000430254ENST00000396653TRAK2chr2202285140-AP1S3chr2224642586-0.33191140.6680886
ENST00000430254ENST00000446015TRAK2chr2202285140-AP1S3chr2224642586-0.26015270.7398473
ENST00000430254ENST00000409375TRAK2chr2202285140-AP1S3chr2224642586-0.21703470.7829653
ENST00000430254ENST00000423110TRAK2chr2202285140-AP1S3chr2224642586-0.209213960.7907861

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Fusion Genomic Features for TRAK2-AP1S3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TRAK2-AP1S3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:202285140/chr2:224642586)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AP1S3

Q96PC3

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking (PubMed:24791904). {ECO:0000269|PubMed:24791904}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRAK2chr2:202285140chr2:224642586ENST00000332624-216134_35430915.0Coiled coilOntology_term=ECO:0000255
HgeneTRAK2chr2:202285140chr2:224642586ENST00000430254-28134_35430312.0Coiled coilOntology_term=ECO:0000255
HgeneTRAK2chr2:202285140chr2:224642586ENST00000332624-21648_35330915.0DomainNote=HAP1 N-terminal
HgeneTRAK2chr2:202285140chr2:224642586ENST00000430254-2848_35330312.0DomainNote=HAP1 N-terminal


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Fusion Gene Sequence for TRAK2-AP1S3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>93720_93720_1_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000332624_AP1S3_chr2_224642586_ENST00000396653_length(transcript)=974nt_BP=520nt
CCTTTGGCTTCCCCAATTGTGTGGGGGCTGCCATTGACCCGGTGTCGCCGCAGAACCGAGGTCGCCGAGTGATGATGTTGTGAAGTCGCC
CGCCTGTCCCTGCCACGCCCGGGCGGTTGCTGGCAGTGGGAGCAGCGGCAGCAGCTTCGGCTGCTGCTTTCAGGCTGCCGCTGCATTAGG
GGCTTCCTGAGGAAGCGCGGGCGGACGACAGAGGATGCCGAACCACTCCAGTCATGACTGTCCAAAGTATGATAATCACATGAGAGTGCT
CGTTGCTACGGATGTCATTTGACTCATCAGAGAAAATCTGTCTAAAAGAAAATATCCATGTGACCAAATCCATTTCATTATTGAATGGCT
TGATGGATTTCCTTTACTCTGATTCATACCAAAGCTGTCCTTCTCAACCAAAGCAAGAAAGGATCCTGCATGAGTCAATCCCAGAATGCA
ATTTTTACATCACCAACAGGTGAAGAAAACCTCATGAATAGCAATCACAGAGACTCGGAGAGCATCACTGATACATTTCATATTGCTCTT
CAGTCGACAAGGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGAT
TATTCTCTCCCGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTGTCTGTGAGCTGGATATTA
TCTTTAATTTTGAAAAGGCTTATTTCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAGGAAACATCCAAGAAAATTGCTGTCAAAG
CCATTGAAGACTCTGATATGTTACAGGAGGTCAGTACGGTTTCCCAAACCATGGGAGAAAGATGATGATGATGATGATGATGGTGTTAAT

>93720_93720_1_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000332624_AP1S3_chr2_224642586_ENST00000396653_length(amino acids)=81AA_BP=

--------------------------------------------------------------
>93720_93720_2_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000332624_AP1S3_chr2_224642586_ENST00000396654_length(transcript)=1215nt_BP=520nt
CCTTTGGCTTCCCCAATTGTGTGGGGGCTGCCATTGACCCGGTGTCGCCGCAGAACCGAGGTCGCCGAGTGATGATGTTGTGAAGTCGCC
CGCCTGTCCCTGCCACGCCCGGGCGGTTGCTGGCAGTGGGAGCAGCGGCAGCAGCTTCGGCTGCTGCTTTCAGGCTGCCGCTGCATTAGG
GGCTTCCTGAGGAAGCGCGGGCGGACGACAGAGGATGCCGAACCACTCCAGTCATGACTGTCCAAAGTATGATAATCACATGAGAGTGCT
CGTTGCTACGGATGTCATTTGACTCATCAGAGAAAATCTGTCTAAAAGAAAATATCCATGTGACCAAATCCATTTCATTATTGAATGGCT
TGATGGATTTCCTTTACTCTGATTCATACCAAAGCTGTCCTTCTCAACCAAAGCAAGAAAGGATCCTGCATGAGTCAATCCCAGAATGCA
ATTTTTACATCACCAACAGGTGAAGAAAACCTCATGAATAGCAATCACAGAGACTCGGAGAGCATCACTGATACATTTCATATTGCTCTT
CAGTCGACAAGGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGAT
TATTCTCTCCCGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGTTTATATTTTTG
CTGTGCAATAGAAAATCAGGACAATGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATATTTTGGAAATGT
CTGTGAGCTGGATATTATCTTTAATTTTGAAAAGGCTTATTTCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAGGAAACATCCAA
GAAAATTGCTGTCAAAGCCATTGAAGACTCTGATATGTTACAGGAGACAATGGAAGAATACATGAACAAGCCTACATTTTAACTGGAAAT
CTACTTGAAGACTCCAGCACTACATGTTATGAAGCTGTAAATAAGCAACGCCTCCCATCCGGTTTTTTGATGGAGCCTCAGGCACCATGC
CAAAAATAATTTAAAGGGATTCTTTGTTAACTAACAAAGTTAAAGTTGTTTAACATATTTATAATTACTATGTGTCTGTATTATTAAAAA

>93720_93720_2_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000332624_AP1S3_chr2_224642586_ENST00000396654_length(amino acids)=154AA_BP=1
MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVEL

--------------------------------------------------------------
>93720_93720_3_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000332624_AP1S3_chr2_224642586_ENST00000409375_length(transcript)=978nt_BP=520nt
CCTTTGGCTTCCCCAATTGTGTGGGGGCTGCCATTGACCCGGTGTCGCCGCAGAACCGAGGTCGCCGAGTGATGATGTTGTGAAGTCGCC
CGCCTGTCCCTGCCACGCCCGGGCGGTTGCTGGCAGTGGGAGCAGCGGCAGCAGCTTCGGCTGCTGCTTTCAGGCTGCCGCTGCATTAGG
GGCTTCCTGAGGAAGCGCGGGCGGACGACAGAGGATGCCGAACCACTCCAGTCATGACTGTCCAAAGTATGATAATCACATGAGAGTGCT
CGTTGCTACGGATGTCATTTGACTCATCAGAGAAAATCTGTCTAAAAGAAAATATCCATGTGACCAAATCCATTTCATTATTGAATGGCT
TGATGGATTTCCTTTACTCTGATTCATACCAAAGCTGTCCTTCTCAACCAAAGCAAGAAAGGATCCTGCATGAGTCAATCCCAGAATGCA
ATTTTTACATCACCAACAGGTGAAGAAAACCTCATGAATAGCAATCACAGAGACTCGGAGAGCATCACTGATACATTTCATATTGCTCTT
CAGTCGACAAGGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGAT
TATTCTCTCCCGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGTTTATATTTTTG
CTGTGCAATAGAAAATCAGGACAATGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATATTTTGGAAATGA
GTTTAATTGCTGGTTTCTCCTAATGAGGCTCCTGTCTGTCTTGGATTCCTGGTCTACGCCTGCCTTGAACTCCGAGGTTCCTCAGCTTGC

>93720_93720_3_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000332624_AP1S3_chr2_224642586_ENST00000409375_length(amino acids)=137AA_BP=1
MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVEL

--------------------------------------------------------------
>93720_93720_4_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000332624_AP1S3_chr2_224642586_ENST00000423110_length(transcript)=832nt_BP=520nt
CCTTTGGCTTCCCCAATTGTGTGGGGGCTGCCATTGACCCGGTGTCGCCGCAGAACCGAGGTCGCCGAGTGATGATGTTGTGAAGTCGCC
CGCCTGTCCCTGCCACGCCCGGGCGGTTGCTGGCAGTGGGAGCAGCGGCAGCAGCTTCGGCTGCTGCTTTCAGGCTGCCGCTGCATTAGG
GGCTTCCTGAGGAAGCGCGGGCGGACGACAGAGGATGCCGAACCACTCCAGTCATGACTGTCCAAAGTATGATAATCACATGAGAGTGCT
CGTTGCTACGGATGTCATTTGACTCATCAGAGAAAATCTGTCTAAAAGAAAATATCCATGTGACCAAATCCATTTCATTATTGAATGGCT
TGATGGATTTCCTTTACTCTGATTCATACCAAAGCTGTCCTTCTCAACCAAAGCAAGAAAGGATCCTGCATGAGTCAATCCCAGAATGCA
ATTTTTACATCACCAACAGGTGAAGAAAACCTCATGAATAGCAATCACAGAGACTCGGAGAGCATCACTGATACATTTCATATTGCTCTT
CAGTCGACAAGGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGAT
TATTCTCTCCCGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGTTTATATTTTTG
CTGTGCAATAGAAAATCAGGACAATGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATATTTTGGAAATAC

>93720_93720_4_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000332624_AP1S3_chr2_224642586_ENST00000423110_length(amino acids)=105AA_BP=1
MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVEL

--------------------------------------------------------------
>93720_93720_5_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000332624_AP1S3_chr2_224642586_ENST00000443700_length(transcript)=2150nt_BP=520nt
CCTTTGGCTTCCCCAATTGTGTGGGGGCTGCCATTGACCCGGTGTCGCCGCAGAACCGAGGTCGCCGAGTGATGATGTTGTGAAGTCGCC
CGCCTGTCCCTGCCACGCCCGGGCGGTTGCTGGCAGTGGGAGCAGCGGCAGCAGCTTCGGCTGCTGCTTTCAGGCTGCCGCTGCATTAGG
GGCTTCCTGAGGAAGCGCGGGCGGACGACAGAGGATGCCGAACCACTCCAGTCATGACTGTCCAAAGTATGATAATCACATGAGAGTGCT
CGTTGCTACGGATGTCATTTGACTCATCAGAGAAAATCTGTCTAAAAGAAAATATCCATGTGACCAAATCCATTTCATTATTGAATGGCT
TGATGGATTTCCTTTACTCTGATTCATACCAAAGCTGTCCTTCTCAACCAAAGCAAGAAAGGATCCTGCATGAGTCAATCCCAGAATGCA
ATTTTTACATCACCAACAGGTGAAGAAAACCTCATGAATAGCAATCACAGAGACTCGGAGAGCATCACTGATACATTTCATATTGCTCTT
CAGTCGACAAGGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGAT
TATTCTCTCCCGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGTTTATATTTTTG
CTGTGCAATAGAAAATCAGGACAATGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATATTTTGGAAATGT
CTGTGAGCTGGATATTATCTTTAATTTTGAAAAGGCTTATTTCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAGGAAACATCCAA
GAAAATTGCTGTCAAAGCCATTGAAGACTCTGATATGTTACAGGAGAATCGTTTGAGCCCCAGAGGCAGAGATTGCAGTGAGCCGAGATC
ATGCCATTGCACTCTAGCCTAGGCAACAAGAGCAAAACTCCATCTAAAAAAAAAAAAAAAGAAAAGAAAAAGGAGAATTATGAAGAACTT
GGTTCCACAAGTAAGATAGTCCTCATACTGCATCAGTAGTGACTTAAACTTTTTTAAAACTTTTATTTTTTGTGGGGGGATCTGTTGAAT
TTGGGAAGCCTCCAGTTTTAATAAAATTTTTTTATTATGGTGGAAACATGTCTGTAAAACTTAGGACTATAGAAATGCAAAGAATAAAGA
ACTGAGGGAGTTACACACATTTGTAGTCAGAAATTAAGTTCAAAAAATAATTTAGGTCATTTGCATTTTTTAGTATGCAAAATAAATGGA
AAAATTAAAGTGCAATAAAAATATAATTTGGGAAATGAATGCAGTAAAATTGAAAACATTGAAATATTATAATTTAATAAAATAAACTTC
AAAAAATGTATGAAAATATAAGTATCTTTACTTATATAGGATTAAATATATTTCTGATAATCTGTCCTCTATAATGAATTGGTTTAATTA
TGTTTTTCTGTTTTTAGAAATGGGCATCTTTTTATTTCTGGAAACAACTTTTTAATGAGATTTTATCAAACATTAGACTATGACTAATTA
TAATATTCAAAGCCAATACCAAAACGATGGATAAATAAATGAATAAAACAAGGCACATTAATAGAAAAAAATGAATGAAATCAATTACGG
GTTCTACTTGAAACACCTAATCTCATTATAATAGCAATAATAAAACAATTTGTACATACTTTATTAGTCGAACATTTATTAAAAATATAA
GAGCATAGAGCAAATTAATTTGGAAGAAAATTTAAATCTTTTACATACAAATACCCTCAAGAATAATAAATCATGGAGTATTAATAAAAT
TAAACCAGCTGATAATTTTAGAAAGTGCTTCATGCACAGAGACTTTTATTCAAGTCCTCTTTGCTTTCTGCTAGTGCTTTTTTTTTTTTC
TTGAAATGGGATGGGATCTCACTCTGTCACCCAGGCTGGAGTGCAGTAGCACGATAGCAGCGCACTGCAACCTGGACCTCCTGGGCTCAA

>93720_93720_5_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000332624_AP1S3_chr2_224642586_ENST00000443700_length(amino acids)=164AA_BP=1
MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVEL

--------------------------------------------------------------
>93720_93720_6_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000332624_AP1S3_chr2_224642586_ENST00000446015_length(transcript)=982nt_BP=520nt
CCTTTGGCTTCCCCAATTGTGTGGGGGCTGCCATTGACCCGGTGTCGCCGCAGAACCGAGGTCGCCGAGTGATGATGTTGTGAAGTCGCC
CGCCTGTCCCTGCCACGCCCGGGCGGTTGCTGGCAGTGGGAGCAGCGGCAGCAGCTTCGGCTGCTGCTTTCAGGCTGCCGCTGCATTAGG
GGCTTCCTGAGGAAGCGCGGGCGGACGACAGAGGATGCCGAACCACTCCAGTCATGACTGTCCAAAGTATGATAATCACATGAGAGTGCT
CGTTGCTACGGATGTCATTTGACTCATCAGAGAAAATCTGTCTAAAAGAAAATATCCATGTGACCAAATCCATTTCATTATTGAATGGCT
TGATGGATTTCCTTTACTCTGATTCATACCAAAGCTGTCCTTCTCAACCAAAGCAAGAAAGGATCCTGCATGAGTCAATCCCAGAATGCA
ATTTTTACATCACCAACAGGTGAAGAAAACCTCATGAATAGCAATCACAGAGACTCGGAGAGCATCACTGATACATTTCATATTGCTCTT
CAGTCGACAAGGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAAATTGTTCAGAT
TATTCTCTCCCGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGTTTATATTTTTG
CTGTGCAATAGAAAATCAGGACAATGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATATTTTGGAAATGT
CTGTGAGCTGGATATTATCTTTAATTTTGAAAAGGCTTATTTCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAGGAAACATCCAA

>93720_93720_6_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000332624_AP1S3_chr2_224642586_ENST00000446015_length(amino acids)=155AA_BP=1
MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVEL

--------------------------------------------------------------
>93720_93720_7_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000430254_AP1S3_chr2_224642586_ENST00000396653_length(transcript)=895nt_BP=441nt
GTGAAGTCGCCCGCCTGTCCCTGCCACGCCCGGGCGGTTGCTGGCAGTGGGAGCAGCGGCAGCAGCTTCGGCTGCTGCTTTCAGGCTGCC
GCTGCATTAGGGGCTTCCTGAGGAAGCGCGGGCGGACGACAGAGGATGCCGAACCACTCCAGTCATGACTGTCCAAAGTATGATAATCAC
ATGAGAGTGCTCGTTGCTACGGATGTCATTTGACTCATCAGAGAAAATCTGTCTAAAAGAAAATATCCATGTGACCAAATCCATTTCATT
ATTGAATGGCTTGATGGATTTCCTTTACTCTGATTCATACCAAAGCTGTCCTTCTCAACCAAAGCAAGAAAGGATCCTGCATGAGTCAAT
CCCAGAATGCAATTTTTACATCACCAACAGGTGAAGAAAACCTCATGAATAGCAATCACAGAGACTCGGAGAGCATCACTGATACATTTC
ATATTGCTCTTCAGTCGACAAGGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAA
ATTGTTCAGATTATTCTCTCCCGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTGTCTGTGA
GCTGGATATTATCTTTAATTTTGAAAAGGCTTATTTCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAGGAAACATCCAAGAAAAT
TGCTGTCAAAGCCATTGAAGACTCTGATATGTTACAGGAGGTCAGTACGGTTTCCCAAACCATGGGAGAAAGATGATGATGATGATGATG

>93720_93720_7_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000430254_AP1S3_chr2_224642586_ENST00000396653_length(amino acids)=70AA_BP=47

--------------------------------------------------------------
>93720_93720_8_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000430254_AP1S3_chr2_224642586_ENST00000396654_length(transcript)=1136nt_BP=441nt
GTGAAGTCGCCCGCCTGTCCCTGCCACGCCCGGGCGGTTGCTGGCAGTGGGAGCAGCGGCAGCAGCTTCGGCTGCTGCTTTCAGGCTGCC
GCTGCATTAGGGGCTTCCTGAGGAAGCGCGGGCGGACGACAGAGGATGCCGAACCACTCCAGTCATGACTGTCCAAAGTATGATAATCAC
ATGAGAGTGCTCGTTGCTACGGATGTCATTTGACTCATCAGAGAAAATCTGTCTAAAAGAAAATATCCATGTGACCAAATCCATTTCATT
ATTGAATGGCTTGATGGATTTCCTTTACTCTGATTCATACCAAAGCTGTCCTTCTCAACCAAAGCAAGAAAGGATCCTGCATGAGTCAAT
CCCAGAATGCAATTTTTACATCACCAACAGGTGAAGAAAACCTCATGAATAGCAATCACAGAGACTCGGAGAGCATCACTGATACATTTC
ATATTGCTCTTCAGTCGACAAGGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAA
ATTGTTCAGATTATTCTCTCCCGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGT
TTATATTTTTGCTGTGCAATAGAAAATCAGGACAATGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATAT
TTTGGAAATGTCTGTGAGCTGGATATTATCTTTAATTTTGAAAAGGCTTATTTCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAG
GAAACATCCAAGAAAATTGCTGTCAAAGCCATTGAAGACTCTGATATGTTACAGGAGACAATGGAAGAATACATGAACAAGCCTACATTT
TAACTGGAAATCTACTTGAAGACTCCAGCACTACATGTTATGAAGCTGTAAATAAGCAACGCCTCCCATCCGGTTTTTTGATGGAGCCTC
AGGCACCATGCCAAAAATAATTTAAAGGGATTCTTTGTTAACTAACAAAGTTAAAGTTGTTTAACATATTTATAATTACTATGTGTCTGT

>93720_93720_8_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000430254_AP1S3_chr2_224642586_ENST00000396654_length(amino acids)=154AA_BP=1
MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVEL

--------------------------------------------------------------
>93720_93720_9_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000430254_AP1S3_chr2_224642586_ENST00000409375_length(transcript)=899nt_BP=441nt
GTGAAGTCGCCCGCCTGTCCCTGCCACGCCCGGGCGGTTGCTGGCAGTGGGAGCAGCGGCAGCAGCTTCGGCTGCTGCTTTCAGGCTGCC
GCTGCATTAGGGGCTTCCTGAGGAAGCGCGGGCGGACGACAGAGGATGCCGAACCACTCCAGTCATGACTGTCCAAAGTATGATAATCAC
ATGAGAGTGCTCGTTGCTACGGATGTCATTTGACTCATCAGAGAAAATCTGTCTAAAAGAAAATATCCATGTGACCAAATCCATTTCATT
ATTGAATGGCTTGATGGATTTCCTTTACTCTGATTCATACCAAAGCTGTCCTTCTCAACCAAAGCAAGAAAGGATCCTGCATGAGTCAAT
CCCAGAATGCAATTTTTACATCACCAACAGGTGAAGAAAACCTCATGAATAGCAATCACAGAGACTCGGAGAGCATCACTGATACATTTC
ATATTGCTCTTCAGTCGACAAGGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAA
ATTGTTCAGATTATTCTCTCCCGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGT
TTATATTTTTGCTGTGCAATAGAAAATCAGGACAATGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATAT
TTTGGAAATGAGTTTAATTGCTGGTTTCTCCTAATGAGGCTCCTGTCTGTCTTGGATTCCTGGTCTACGCCTGCCTTGAACTCCGAGGTT

>93720_93720_9_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000430254_AP1S3_chr2_224642586_ENST00000409375_length(amino acids)=137AA_BP=1
MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVEL

--------------------------------------------------------------
>93720_93720_10_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000430254_AP1S3_chr2_224642586_ENST00000423110_length(transcript)=753nt_BP=441nt
GTGAAGTCGCCCGCCTGTCCCTGCCACGCCCGGGCGGTTGCTGGCAGTGGGAGCAGCGGCAGCAGCTTCGGCTGCTGCTTTCAGGCTGCC
GCTGCATTAGGGGCTTCCTGAGGAAGCGCGGGCGGACGACAGAGGATGCCGAACCACTCCAGTCATGACTGTCCAAAGTATGATAATCAC
ATGAGAGTGCTCGTTGCTACGGATGTCATTTGACTCATCAGAGAAAATCTGTCTAAAAGAAAATATCCATGTGACCAAATCCATTTCATT
ATTGAATGGCTTGATGGATTTCCTTTACTCTGATTCATACCAAAGCTGTCCTTCTCAACCAAAGCAAGAAAGGATCCTGCATGAGTCAAT
CCCAGAATGCAATTTTTACATCACCAACAGGTGAAGAAAACCTCATGAATAGCAATCACAGAGACTCGGAGAGCATCACTGATACATTTC
ATATTGCTCTTCAGTCGACAAGGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAA
ATTGTTCAGATTATTCTCTCCCGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGT
TTATATTTTTGCTGTGCAATAGAAAATCAGGACAATGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATAT

>93720_93720_10_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000430254_AP1S3_chr2_224642586_ENST00000423110_length(amino acids)=104AA_BP=1
MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVEL

--------------------------------------------------------------
>93720_93720_11_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000430254_AP1S3_chr2_224642586_ENST00000443700_length(transcript)=2071nt_BP=441nt
GTGAAGTCGCCCGCCTGTCCCTGCCACGCCCGGGCGGTTGCTGGCAGTGGGAGCAGCGGCAGCAGCTTCGGCTGCTGCTTTCAGGCTGCC
GCTGCATTAGGGGCTTCCTGAGGAAGCGCGGGCGGACGACAGAGGATGCCGAACCACTCCAGTCATGACTGTCCAAAGTATGATAATCAC
ATGAGAGTGCTCGTTGCTACGGATGTCATTTGACTCATCAGAGAAAATCTGTCTAAAAGAAAATATCCATGTGACCAAATCCATTTCATT
ATTGAATGGCTTGATGGATTTCCTTTACTCTGATTCATACCAAAGCTGTCCTTCTCAACCAAAGCAAGAAAGGATCCTGCATGAGTCAAT
CCCAGAATGCAATTTTTACATCACCAACAGGTGAAGAAAACCTCATGAATAGCAATCACAGAGACTCGGAGAGCATCACTGATACATTTC
ATATTGCTCTTCAGTCGACAAGGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAA
ATTGTTCAGATTATTCTCTCCCGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGT
TTATATTTTTGCTGTGCAATAGAAAATCAGGACAATGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATAT
TTTGGAAATGTCTGTGAGCTGGATATTATCTTTAATTTTGAAAAGGCTTATTTCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAG
GAAACATCCAAGAAAATTGCTGTCAAAGCCATTGAAGACTCTGATATGTTACAGGAGAATCGTTTGAGCCCCAGAGGCAGAGATTGCAGT
GAGCCGAGATCATGCCATTGCACTCTAGCCTAGGCAACAAGAGCAAAACTCCATCTAAAAAAAAAAAAAAAGAAAAGAAAAAGGAGAATT
ATGAAGAACTTGGTTCCACAAGTAAGATAGTCCTCATACTGCATCAGTAGTGACTTAAACTTTTTTAAAACTTTTATTTTTTGTGGGGGG
ATCTGTTGAATTTGGGAAGCCTCCAGTTTTAATAAAATTTTTTTATTATGGTGGAAACATGTCTGTAAAACTTAGGACTATAGAAATGCA
AAGAATAAAGAACTGAGGGAGTTACACACATTTGTAGTCAGAAATTAAGTTCAAAAAATAATTTAGGTCATTTGCATTTTTTAGTATGCA
AAATAAATGGAAAAATTAAAGTGCAATAAAAATATAATTTGGGAAATGAATGCAGTAAAATTGAAAACATTGAAATATTATAATTTAATA
AAATAAACTTCAAAAAATGTATGAAAATATAAGTATCTTTACTTATATAGGATTAAATATATTTCTGATAATCTGTCCTCTATAATGAAT
TGGTTTAATTATGTTTTTCTGTTTTTAGAAATGGGCATCTTTTTATTTCTGGAAACAACTTTTTAATGAGATTTTATCAAACATTAGACT
ATGACTAATTATAATATTCAAAGCCAATACCAAAACGATGGATAAATAAATGAATAAAACAAGGCACATTAATAGAAAAAAATGAATGAA
ATCAATTACGGGTTCTACTTGAAACACCTAATCTCATTATAATAGCAATAATAAAACAATTTGTACATACTTTATTAGTCGAACATTTAT
TAAAAATATAAGAGCATAGAGCAAATTAATTTGGAAGAAAATTTAAATCTTTTACATACAAATACCCTCAAGAATAATAAATCATGGAGT
ATTAATAAAATTAAACCAGCTGATAATTTTAGAAAGTGCTTCATGCACAGAGACTTTTATTCAAGTCCTCTTTGCTTTCTGCTAGTGCTT
TTTTTTTTTTCTTGAAATGGGATGGGATCTCACTCTGTCACCCAGGCTGGAGTGCAGTAGCACGATAGCAGCGCACTGCAACCTGGACCT
CCTGGGCTCAAGCAATCCTCTCACCGCAGCCTCCTGAGTAGCTGGGGCTACAGGTGTGTGCCACCATACTTGGCTAATTAAAAAAAAAAA

>93720_93720_11_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000430254_AP1S3_chr2_224642586_ENST00000443700_length(amino acids)=164AA_BP=1
MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVEL

--------------------------------------------------------------
>93720_93720_12_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000430254_AP1S3_chr2_224642586_ENST00000446015_length(transcript)=903nt_BP=441nt
GTGAAGTCGCCCGCCTGTCCCTGCCACGCCCGGGCGGTTGCTGGCAGTGGGAGCAGCGGCAGCAGCTTCGGCTGCTGCTTTCAGGCTGCC
GCTGCATTAGGGGCTTCCTGAGGAAGCGCGGGCGGACGACAGAGGATGCCGAACCACTCCAGTCATGACTGTCCAAAGTATGATAATCAC
ATGAGAGTGCTCGTTGCTACGGATGTCATTTGACTCATCAGAGAAAATCTGTCTAAAAGAAAATATCCATGTGACCAAATCCATTTCATT
ATTGAATGGCTTGATGGATTTCCTTTACTCTGATTCATACCAAAGCTGTCCTTCTCAACCAAAGCAAGAAAGGATCCTGCATGAGTCAAT
CCCAGAATGCAATTTTTACATCACCAACAGGTGAAGAAAACCTCATGAATAGCAATCACAGAGACTCGGAGAGCATCACTGATACATTTC
ATATTGCTCTTCAGTCGACAAGGGAAATTACGGCTACAGAAATGGTACATCACTCTCCCTGATAAAGAGAGGAAGAAGATCACCCGGGAA
ATTGTTCAGATTATTCTCTCCCGTGGTCACAGGACAAGCAGTTTTGTTGACTGGAAGGAGCTAAAACTTGTTTATAAAAGGTATGCTAGT
TTATATTTTTGCTGTGCAATAGAAAATCAGGACAATGAGCTCTTGACGCTAGAGATTGTGCATCGTTACGTGGAGCTGCTGGACAAATAT
TTTGGAAATGTCTGTGAGCTGGATATTATCTTTAATTTTGAAAAGGCTTATTTCATCCTGGACGAGTTTATAATAGGTGGGGAAATTCAG
GAAACATCCAAGAAAATTGCTGTCAAAGCCATTGAAGACTCTGATATGTTACAGGAGGTCAGTACGGTTTCCCAAACCATGGGAGAAAGA

>93720_93720_12_TRAK2-AP1S3_TRAK2_chr2_202285140_ENST00000430254_AP1S3_chr2_224642586_ENST00000446015_length(amino acids)=154AA_BP=1
MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVEL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TRAK2-AP1S3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneTRAK2chr2:202285140chr2:224642586ENST00000332624-216359_50930.333333333333332915.0HGS
HgeneTRAK2chr2:202285140chr2:224642586ENST00000430254-28359_50930.333333333333332312.0HGS


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TRAK2-AP1S3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TRAK2-AP1S3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource