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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TRAM1-ZFPM2 (FusionGDB2 ID:93740)

Fusion Gene Summary for TRAM1-ZFPM2

check button Fusion gene summary
Fusion gene informationFusion gene name: TRAM1-ZFPM2
Fusion gene ID: 93740
HgeneTgene
Gene symbol

TRAM1

ZFPM2

Gene ID

23471

23414

Gene nametranslocation associated membrane protein 1zinc finger protein, FOG family member 2
SynonymsPNAS8|TRAM|TRAMPDIH3|FOG2|SRXY9|ZC2HC11B|ZNF89B|hFOG-2
Cytomap

8q13.3

8q23.1

Type of geneprotein-codingprotein-coding
Descriptiontranslocating chain-associated membrane protein 1translocating chain-associating membrane proteintranslocation-associating membrane protein 1zinc finger protein ZFPM2FOG-2Friend of GATA2friend of GATA 2friend of GATA protein 2transcription factor GATA4, modulator ofzinc finger protein 89Bzinc finger protein, multitype 2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000262213, ENST00000521425, 
ENST00000536748, ENST00000521049, 
ENST00000378472, ENST00000522296, 
ENST00000407775, ENST00000517361, 
ENST00000520492, 
Fusion gene scores* DoF score13 X 14 X 3=54621 X 21 X 8=3528
# samples 1425
** MAII scorelog2(14/546*10)=-1.96347412397489
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(25/3528*10)=-3.81885056089543
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TRAM1 [Title/Abstract] AND ZFPM2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTRAM1(71506741)-ZFPM2(106646474), # samples:3
Anticipated loss of major functional domain due to fusion event.TRAM1-ZFPM2 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
TRAM1-ZFPM2 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneZFPM2

GO:0045892

negative regulation of transcription, DNA-templated

20206639

TgeneZFPM2

GO:0045944

positive regulation of transcription by RNA polymerase II

10438528


check buttonFusion gene breakpoints across TRAM1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZFPM2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A097-01ATRAM1chr8

71506741

-ZFPM2chr8

106646474

+
ChimerDB4BRCATCGA-A8-A097TRAM1chr8

71506740

-ZFPM2chr8

106646473

+


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Fusion Gene ORF analysis for TRAM1-ZFPM2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000262213ENST00000378472TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
5CDS-intronENST00000262213ENST00000378472TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
5CDS-intronENST00000262213ENST00000522296TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
5CDS-intronENST00000262213ENST00000522296TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
5CDS-intronENST00000521425ENST00000378472TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
5CDS-intronENST00000521425ENST00000378472TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
5CDS-intronENST00000521425ENST00000522296TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
5CDS-intronENST00000521425ENST00000522296TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
5CDS-intronENST00000536748ENST00000378472TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
5CDS-intronENST00000536748ENST00000378472TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
5CDS-intronENST00000536748ENST00000522296TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
5CDS-intronENST00000536748ENST00000522296TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
Frame-shiftENST00000521425ENST00000407775TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
Frame-shiftENST00000521425ENST00000407775TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
Frame-shiftENST00000521425ENST00000517361TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
Frame-shiftENST00000521425ENST00000517361TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
Frame-shiftENST00000521425ENST00000520492TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
Frame-shiftENST00000521425ENST00000520492TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
Frame-shiftENST00000536748ENST00000407775TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
Frame-shiftENST00000536748ENST00000407775TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
Frame-shiftENST00000536748ENST00000517361TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
Frame-shiftENST00000536748ENST00000517361TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
Frame-shiftENST00000536748ENST00000520492TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
Frame-shiftENST00000536748ENST00000520492TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
In-frameENST00000262213ENST00000407775TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
In-frameENST00000262213ENST00000407775TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
In-frameENST00000262213ENST00000517361TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
In-frameENST00000262213ENST00000517361TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
In-frameENST00000262213ENST00000520492TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
In-frameENST00000262213ENST00000520492TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
intron-3CDSENST00000521049ENST00000407775TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
intron-3CDSENST00000521049ENST00000407775TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
intron-3CDSENST00000521049ENST00000517361TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
intron-3CDSENST00000521049ENST00000517361TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
intron-3CDSENST00000521049ENST00000520492TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
intron-3CDSENST00000521049ENST00000520492TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
intron-intronENST00000521049ENST00000378472TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
intron-intronENST00000521049ENST00000378472TRAM1chr8

71506740

-ZFPM2chr8

106646473

+
intron-intronENST00000521049ENST00000522296TRAM1chr8

71506741

-ZFPM2chr8

106646474

+
intron-intronENST00000521049ENST00000522296TRAM1chr8

71506740

-ZFPM2chr8

106646473

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000262213TRAM1chr871506741-ENST00000407775ZFPM2chr8106646474+47707405937751238
ENST00000262213TRAM1chr871506741-ENST00000520492ZFPM2chr8106646474+41087405937751238
ENST00000262213TRAM1chr871506741-ENST00000517361ZFPM2chr8106646474+38357405937751238
ENST00000262213TRAM1chr871506740-ENST00000407775ZFPM2chr8106646473+47707405937751238
ENST00000262213TRAM1chr871506740-ENST00000520492ZFPM2chr8106646473+41087405937751238
ENST00000262213TRAM1chr871506740-ENST00000517361ZFPM2chr8106646473+38357405937751238

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000262213ENST00000407775TRAM1chr871506741-ZFPM2chr8106646474+0.0006204240.9993795
ENST00000262213ENST00000520492TRAM1chr871506741-ZFPM2chr8106646474+0.0009694190.9990306
ENST00000262213ENST00000517361TRAM1chr871506741-ZFPM2chr8106646474+0.0014237010.9985763
ENST00000262213ENST00000407775TRAM1chr871506740-ZFPM2chr8106646473+0.0006204240.9993795
ENST00000262213ENST00000520492TRAM1chr871506740-ZFPM2chr8106646473+0.0009694190.9990306
ENST00000262213ENST00000517361TRAM1chr871506740-ZFPM2chr8106646473+0.0014237010.9985763

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Fusion Genomic Features for TRAM1-ZFPM2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TRAM1chr871506740-ZFPM2chr8106646473+5.22E-081
TRAM1chr871506740-ZFPM2chr8106646473+5.22E-081
TRAM1chr871506740-ZFPM2chr8106646473+5.22E-081
TRAM1chr871506740-ZFPM2chr8106646473+5.22E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for TRAM1-ZFPM2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:71506741/chr8:106646474)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-611143_159190375.0Topological domainLumenal
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-611181_192190375.0Topological domainCytoplasmic
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-6111_29190375.0Topological domainCytoplasmic
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-61151_76190375.0Topological domainLumenal
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-61198_121190375.0Topological domainCytoplasmic
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-611143_159190375.0Topological domainLumenal
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-611181_192190375.0Topological domainCytoplasmic
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-6111_29190375.0Topological domainCytoplasmic
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-61151_76190375.0Topological domainLumenal
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-61198_121190375.0Topological domainCytoplasmic
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-611122_142190375.0TransmembraneHelical
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-611160_180190375.0TransmembraneHelical
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-61130_50190375.0TransmembraneHelical
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-61177_97190375.0TransmembraneHelical
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-611122_142190375.0TransmembraneHelical
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-611160_180190375.0TransmembraneHelical
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-61130_50190375.0TransmembraneHelical
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-61177_97190375.0TransmembraneHelical
TgeneZFPM2chr8:71506740chr8:106646473ENST0000040777538736_7401401152.0MotifNuclear localization signal
TgeneZFPM2chr8:71506741chr8:106646474ENST0000040777538736_7401401152.0MotifNuclear localization signal
TgeneZFPM2chr8:71506740chr8:106646473ENST00000407775381113_11461401152.0Zinc fingerCCHC FOG-type 5
TgeneZFPM2chr8:71506740chr8:106646473ENST0000040777538244_2771401152.0Zinc fingerCCHC FOG-type 1
TgeneZFPM2chr8:71506740chr8:106646473ENST0000040777538296_3201401152.0Zinc fingerC2H2-type 1
TgeneZFPM2chr8:71506740chr8:106646473ENST0000040777538335_3571401152.0Zinc fingerC2H2-type 2
TgeneZFPM2chr8:71506740chr8:106646473ENST0000040777538363_3851401152.0Zinc fingerC2H2-type 3
TgeneZFPM2chr8:71506740chr8:106646473ENST0000040777538542_5751401152.0Zinc fingerCCHC FOG-type 2
TgeneZFPM2chr8:71506740chr8:106646473ENST0000040777538681_7141401152.0Zinc fingerCCHC FOG-type 3
TgeneZFPM2chr8:71506740chr8:106646473ENST0000040777538848_8811401152.0Zinc fingerCCHC FOG-type 4
TgeneZFPM2chr8:71506741chr8:106646474ENST00000407775381113_11461401152.0Zinc fingerCCHC FOG-type 5
TgeneZFPM2chr8:71506741chr8:106646474ENST0000040777538244_2771401152.0Zinc fingerCCHC FOG-type 1
TgeneZFPM2chr8:71506741chr8:106646474ENST0000040777538296_3201401152.0Zinc fingerC2H2-type 1
TgeneZFPM2chr8:71506741chr8:106646474ENST0000040777538335_3571401152.0Zinc fingerC2H2-type 2
TgeneZFPM2chr8:71506741chr8:106646474ENST0000040777538363_3851401152.0Zinc fingerC2H2-type 3
TgeneZFPM2chr8:71506741chr8:106646474ENST0000040777538542_5751401152.0Zinc fingerCCHC FOG-type 2
TgeneZFPM2chr8:71506741chr8:106646474ENST0000040777538681_7141401152.0Zinc fingerCCHC FOG-type 3
TgeneZFPM2chr8:71506741chr8:106646474ENST0000040777538848_8811401152.0Zinc fingerCCHC FOG-type 4

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-611117_326190375.0DomainTLC
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-611117_326190375.0DomainTLC
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-611214_217190375.0Topological domainLumenal
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-611239_251190375.0Topological domainCytoplasmic
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-611273_297190375.0Topological domainLumenal
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-611319_374190375.0Topological domainCytoplasmic
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-611214_217190375.0Topological domainLumenal
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-611239_251190375.0Topological domainCytoplasmic
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-611273_297190375.0Topological domainLumenal
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-611319_374190375.0Topological domainCytoplasmic
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-611193_213190375.0TransmembraneHelical
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-611218_238190375.0TransmembraneHelical
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-611252_272190375.0TransmembraneHelical
HgeneTRAM1chr8:71506740chr8:106646473ENST00000262213-611298_318190375.0TransmembraneHelical
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-611193_213190375.0TransmembraneHelical
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-611218_238190375.0TransmembraneHelical
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-611252_272190375.0TransmembraneHelical
HgeneTRAM1chr8:71506741chr8:106646474ENST00000262213-611298_318190375.0TransmembraneHelical


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Fusion Gene Sequence for TRAM1-ZFPM2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>93740_93740_1_TRAM1-ZFPM2_TRAM1_chr8_71506740_ENST00000262213_ZFPM2_chr8_106646473_ENST00000407775_length(transcript)=4770nt_BP=740nt
CGGGCGGCCCGGCGGCTGCGTACTGGCTGTGGGATGGGAAGTGAAGCCCCAGCGAGCGGCTGCAGCGGGGCCGTGAGGAGCAGCCAGCGG
GAGGCGGCGGCGAGTCGGTGAGCAGCTGGGAAGAGCAGAACCGGGGCGGAGCACCTGCAGGCGCGGGCGGCGGCCCCACCATGGCGATTC
GCAAGAAAAGCACCAAGAGCCCCCCAGTGCTGAGCCACGAATTCGTCCTGCAGAATCACGCGGACATCGTCTCCTGTGTGGCGATGGTCT
TCCTGCTGGGGCTCATGTTTGAGATAACGGCAAAAGCTTCTATCATTTTTGTTACTCTTCAGTACAATGTCACCCTCCCAGCAACAGAAG
AACAAGCTACTGAATCAGTGTCCCTTTATTACTATGGCATCAAAGATTTGGCTACTGTTTTCTTCTACATGCTAGTGGCGATAATTATTC
ATGCCGTAATTCAAGAGTATATGTTGGATAAAATTAACAGGCGAATGCACTTCTCCAAAACAAAACACAGCAAGTTTAATGAATCTGGTC
AGCTTAGTGCGTTCTACCTTTTTGCCTGTGTTTGGGGCACATTCATTCTCATCTCTGAAAACTACATCTCAGACCCAACTATCTTATGGA
GGGCTTATCCCCATAACCTGATGACATTTCAAATGAAGTTTTTCTACATATCACAGCTGGCTTACTGGCTTCATGCTTTTCCTGAACTCT
ACTTCCAGAAAACCAAAAAAAAGACAAAGGCTCAGGTCCCAATGGTGCTGACTGCTGGTCCCAAGTGGTTGCTGGATGTGACTTGGCAAG
GAGTGGAAGACAACAAAAACAACTGCATTGTGTACAGCAAAGGGGGTCAGCTTTGGTGTACAACTACGAAGGCCATCTCTGAGGGTGAAG
AGCTAATTGCCTTTGTGGTGGATTTTGACTCAAGGCTACAAGCTGCCAGTCAGATGACTCTCACAGAAGGGATGTACCCTGCACGCCTGC
TGGACTCAATTCAGCTGCTTCCTCAGCAAGCTGCCATGGCTTCTATTTTGCCCACAGCTATTGTCAATAAGGATATATTCCCTTGCAAGT
CCTGTGGCATCTGGTATCGGAGTGAGCGGAATCTGCAGGCCCATTTGATGTACTACTGCAGTGGGAGGCAAAGAGAAGCTGCTCCGGTGT
CAGAGGAAAATGAAGACAGTGCCCATCAGATTTCCAGCCTGTGCCCCTTCCCACAGTGCACCAAGAGCTTTTCAAATGCTCGAGCTCTAG
AAATGCACCTGAATTCACACAGTGGAGTGAAAATGGAAGAATTCCTGCCCCCTGGTGCTAGTCTAAAATGCACCGTCTGTAGCTACACTG
CTGATTCCGTGATCAACTTTCACCAACACCTGTTCTCCCATCTCACTCAAGCTGCCTTCCGATGTAATCACTGCCATTTCGGCTTCCAGA
CTCAGAGGGAGTTATTGCAGCACCAGGAGCTCCATGTCCCTAGCGGCAAACTTCCCAGAGAAAGTGACATGGAACACTCTCCAAGTGCAA
CTGAAGACAGCTTACAGCCAGCCACAGACTTATTGACCAGAAGCGAACTTCCCCAGAGCCAAAAGGCCATGCAGACTAAAGATGCGAGCT
CTGACACAGAGCTGGACAAGTGTGAGAAAAAGACTCAGCTCTTTCTCACGAACCAGAGACCAGAGATACAGCCTACAACAAATAAACAAA
GCTTTTCTTACACAAAAATAAAGTCTGAGCCCTCTAGCCCAAGACTTGCCTCATCTCCAGTTCAGCCTAATATTGGGCCTTCTTTCCCTG
TGGGCCCTTTCCTATCTCAGTTTTCTTTCCCCCAAGATATCACCATGGTCCCTCAAGCTTCAGAGATCTTAGCTAAGATGTCTGAACTGG
TGCATCGGCGACTGAGGCATGGCAGTAGTAGCTACCCTCCCGTCATTTACAGCCCTTTGATGCCCAAGGGGGCTACTTGTTTTGAGTGTA
ACATAACATTCAATAATTTGGATAATTATCTAGTGCACAAAAAGCATTATTGCAGCAGCCGATGGCAGCAGATGGCTAAGTCCCCAGAGT
TCCCTAGTGTGTCAGAAAAGATGCCTGAAGCTTTGAGTCCCAACACTGGCCAAACCTCCATAAACCTTCTCAACCCAGCTGCTCATTCTG
CTGATCCTGAGAATCCACTTCTTCAAACATCTTGCATCAATTCTTCCACTGTCTTAGATTTAATTGGGCCAAATGGGAAGGGCCATGACA
AGGACTTTTCCACTCAAACTAAGAAGCTCTCCACCTCCAGTAACAATGATGACAAAATTAATGGAAAACCTGTTGATGTGAAAAATCCCA
GTGTCCCCTTAGTGGATGGGGAAAGTGACCCAAATAAGACTACCTGTGAAGCTTGCAACATTACCTTCAGCCGGCACGAAACATACATGG
TCCACAAACAGTATTACTGTGCTACACGCCACGACCCTCCACTGAAGAGGTCTGCTTCCAACAAAGTGCCTGCCATGCAGAGAACCATGC
GCACACGCAAGCGCAGAAAGATGTATGAGATGTGCCTACCTGAGCAGGAACAAAGGCCTCCACTGGTTCAGCAGAGATTTCTTGACGTAG
CCAACCTCAATAATCCTTGTACCTCCACTCAAGAACCCACAGAAGGGCTAGGAGAGTGCTACCACCCAAGATGTGATATCTTTCCAGGAA
TTGTCTCTAAACACTTGGAAACTTCTCTGACGATCAACAAGTGTGTTCCAGTTTCCAAATGTGATACTACTCATTCCAGTGTTTCCTGCC
TAGAGATGGACGTGCCCATAGATCTCAGCAAAAAGTGTTTATCTCAGTCTGAGCGGACGACCACGTCTCCCAAAAGGCTGCTGGACTATC
ACGAGTGCACTGTGTGCAAGATCAGTTTCAATAAGGTAGAAAACTATCTGGCCCACAAGCAGAATTTCTGCCCGGTTACTGCACATCAGC
GTAATGACCTGGGTCAACTGGACGGCAAAGTGTTTCCGAATCCAGAAAGCGAACGAAACAGCCCTGATGTCAGCTACGAAAGAAGCATAA
TAAAATGTGAGAAAAATGGGAATTTGAAGCAGCCTTCCCCCAATGGAAACTTATTTTCATCCCACCTAGCAACCCTGCAAGGCTTGAAGG
TCTTTAGTGAAGCTGCTCAGCTCATTGCTACAAAAGAAGAAAACAGACATTTGTTTCTTCCACAATGCCTTTACCCTGGAGCAATAAAGA
AAGCAAAAGGAGCCGACCAGCTTTCTCCATATTATGGAATCAAGCCAAGTGATTATATTTCTGGTTCTCTTGTCATCCATAACACTGACA
TCGAGCAAAGCAGAAATGCAGAAAATGAATCTCCTAAAGGCCAGGCTTCCTCAAATGGGTGTGCTGCGCTGAAGAAAGATTCTCTGCCAT
TGTTGCCCAAAAATCGAGGAATGGTAATAGTGAATGGTGGACTGAAACAAGATGAGAGACCTGCTGCCAACCCACAGCAAGAGAACATTT
CCCAGAATCCTCAGCACGAAGACGACCACAAATCTCCCTCGTGGATCTCTGAGAACCCATTAGCTGCCAATGAGAATGTCTCACCAGGAA
TTCCCTCAGCAGAGGAACAGTTGTCTAGTATAGCAAAAGGTGTGAATGGTTCCAGCCAGGCTCCAACCAGTGGGAAATATTGCCGGCTAT
GTGATATCCAGTTCAACAACCTTTCAAACTTTATAACTCACAAGAAGTTTTATTGCTCATCACATGCAGCAGAACATGTCAAATGAACTA
ACTAAACATCAGTCACCTTTGGTATCAGTGTTTAGTATGTTGTTCTAACCAGTCCAGAAAAAAAAATAAGCTGTTTGAATTACATCTGGG
CAATCAGGAGATAATTCATTATGGCTGAGTTGAAGACTTAAGGTGTAATTTCATTACAGTCCATTAGTAAAGTGTATTATTGGTGCCATT
TTCAAAAAAATTAATTTATTTTACCAGCAGTATTCATAGCTGTGGTTATGTTATTTTTTATTTAAAAACTTTATATTAAAGTCATTTGTA
ATGTTATTGTATAGTTATTGTGTAGCACATATGGTTTGCACTGTATAGTAGCTTTTAAAGAAAATAGTCACAATACAGAAAAGCATTTTA
GAAATAGCTTCAAAAGCACTTGTGTATCTTGATTTTTTCTTATATGCTGTTGCAGATATATGTATATGCTAAAATATAACTTGCAAAGAT
GTTCTAAATACACATGCTATAAGTTCGCCTTAAGATTTCAATTCTTGGATAATCAGGCTCTGTTTGCACTTTATATTTTAGCAGATACAG
TCTCTTAGTCACTAGGCTTTGCATTTGTATGTAGCTGTATGTTTCCGTCCATTTTCTTAATCCTGAACCTGTATGTTAAATGAAGATGGC
AATTTTTTTCTTGTATAGTACTTGTATTTTCTTTCGCTGATGCAGCTCTGTCTCAATTTTTAAACCTTTGCTGTTAAATGCAATACTTTA
TAAAGAATGAACAAAATTACTGGAAGCAGTATTGTAAGTAATGAGGTAGTATTAATCAGTTTTATCTTTTGAAAGGCACAGTCTAAATCG
AAACCCTAAACTCAATGCTGCAAGTATGAATTTAATTCATATATAAGATCTATTTAAATATAAGAGTAGCAATACTGCACCTGGTGATCA
CAAAGATAATGTTCTACTTCTGATAGAAATAATTTCTCAACAAATGTTGTTACTATGCATGTATATGGATGGAATAAAATTCCAGATTGT

>93740_93740_1_TRAM1-ZFPM2_TRAM1_chr8_71506740_ENST00000262213_ZFPM2_chr8_106646473_ENST00000407775_length(amino acids)=1238AA_BP=227
MQRGREEQPAGGGGESVSSWEEQNRGGAPAGAGGGPTMAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTL
QYNVTLPATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISE
NYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKKKTKAQVPMVLTAGPKWLLDVTWQGVEDNKNNCIVYSKGGQLWC
TTTKAISEGEELIAFVVDFDSRLQAASQMTLTEGMYPARLLDSIQLLPQQAAMASILPTAIVNKDIFPCKSCGIWYRSERNLQAHLMYYC
SGRQREAAPVSEENEDSAHQISSLCPFPQCTKSFSNARALEMHLNSHSGVKMEEFLPPGASLKCTVCSYTADSVINFHQHLFSHLTQAAF
RCNHCHFGFQTQRELLQHQELHVPSGKLPRESDMEHSPSATEDSLQPATDLLTRSELPQSQKAMQTKDASSDTELDKCEKKTQLFLTNQR
PEIQPTTNKQSFSYTKIKSEPSSPRLASSPVQPNIGPSFPVGPFLSQFSFPQDITMVPQASEILAKMSELVHRRLRHGSSSYPPVIYSPL
MPKGATCFECNITFNNLDNYLVHKKHYCSSRWQQMAKSPEFPSVSEKMPEALSPNTGQTSINLLNPAAHSADPENPLLQTSCINSSTVLD
LIGPNGKGHDKDFSTQTKKLSTSSNNDDKINGKPVDVKNPSVPLVDGESDPNKTTCEACNITFSRHETYMVHKQYYCATRHDPPLKRSAS
NKVPAMQRTMRTRKRRKMYEMCLPEQEQRPPLVQQRFLDVANLNNPCTSTQEPTEGLGECYHPRCDIFPGIVSKHLETSLTINKCVPVSK
CDTTHSSVSCLEMDVPIDLSKKCLSQSERTTTSPKRLLDYHECTVCKISFNKVENYLAHKQNFCPVTAHQRNDLGQLDGKVFPNPESERN
SPDVSYERSIIKCEKNGNLKQPSPNGNLFSSHLATLQGLKVFSEAAQLIATKEENRHLFLPQCLYPGAIKKAKGADQLSPYYGIKPSDYI
SGSLVIHNTDIEQSRNAENESPKGQASSNGCAALKKDSLPLLPKNRGMVIVNGGLKQDERPAANPQQENISQNPQHEDDHKSPSWISENP

--------------------------------------------------------------
>93740_93740_2_TRAM1-ZFPM2_TRAM1_chr8_71506740_ENST00000262213_ZFPM2_chr8_106646473_ENST00000517361_length(transcript)=3835nt_BP=740nt
CGGGCGGCCCGGCGGCTGCGTACTGGCTGTGGGATGGGAAGTGAAGCCCCAGCGAGCGGCTGCAGCGGGGCCGTGAGGAGCAGCCAGCGG
GAGGCGGCGGCGAGTCGGTGAGCAGCTGGGAAGAGCAGAACCGGGGCGGAGCACCTGCAGGCGCGGGCGGCGGCCCCACCATGGCGATTC
GCAAGAAAAGCACCAAGAGCCCCCCAGTGCTGAGCCACGAATTCGTCCTGCAGAATCACGCGGACATCGTCTCCTGTGTGGCGATGGTCT
TCCTGCTGGGGCTCATGTTTGAGATAACGGCAAAAGCTTCTATCATTTTTGTTACTCTTCAGTACAATGTCACCCTCCCAGCAACAGAAG
AACAAGCTACTGAATCAGTGTCCCTTTATTACTATGGCATCAAAGATTTGGCTACTGTTTTCTTCTACATGCTAGTGGCGATAATTATTC
ATGCCGTAATTCAAGAGTATATGTTGGATAAAATTAACAGGCGAATGCACTTCTCCAAAACAAAACACAGCAAGTTTAATGAATCTGGTC
AGCTTAGTGCGTTCTACCTTTTTGCCTGTGTTTGGGGCACATTCATTCTCATCTCTGAAAACTACATCTCAGACCCAACTATCTTATGGA
GGGCTTATCCCCATAACCTGATGACATTTCAAATGAAGTTTTTCTACATATCACAGCTGGCTTACTGGCTTCATGCTTTTCCTGAACTCT
ACTTCCAGAAAACCAAAAAAAAGACAAAGGCTCAGGTCCCAATGGTGCTGACTGCTGGTCCCAAGTGGTTGCTGGATGTGACTTGGCAAG
GAGTGGAAGACAACAAAAACAACTGCATTGTGTACAGCAAAGGGGGTCAGCTTTGGTGTACAACTACGAAGGCCATCTCTGAGGGTGAAG
AGCTAATTGCCTTTGTGGTGGATTTTGACTCAAGGCTACAAGCTGCCAGTCAGATGACTCTCACAGAAGGGATGTACCCTGCACGCCTGC
TGGACTCAATTCAGCTGCTTCCTCAGCAAGCTGCCATGGCTTCTATTTTGCCCACAGCTATTGTCAATAAGGATATATTCCCTTGCAAGT
CCTGTGGCATCTGGTATCGGAGTGAGCGGAATCTGCAGGCCCATTTGATGTACTACTGCAGTGGGAGGCAAAGAGAAGCTGCTCCGGTGT
CAGAGGAAAATGAAGACAGTGCCCATCAGATTTCCAGCCTGTGCCCCTTCCCACAGTGCACCAAGAGCTTTTCAAATGCTCGAGCTCTAG
AAATGCACCTGAATTCACACAGTGGAGTGAAAATGGAAGAATTCCTGCCCCCTGGTGCTAGTCTAAAATGCACCGTCTGTAGCTACACTG
CTGATTCCGTGATCAACTTTCACCAACACCTGTTCTCCCATCTCACTCAAGCTGCCTTCCGATGTAATCACTGCCATTTCGGCTTCCAGA
CTCAGAGGGAGTTATTGCAGCACCAGGAGCTCCATGTCCCTAGCGGCAAACTTCCCAGAGAAAGTGACATGGAACACTCTCCAAGTGCAA
CTGAAGACAGCTTACAGCCAGCCACAGACTTATTGACCAGAAGCGAACTTCCCCAGAGCCAAAAGGCCATGCAGACTAAAGATGCGAGCT
CTGACACAGAGCTGGACAAGTGTGAGAAAAAGACTCAGCTCTTTCTCACGAACCAGAGACCAGAGATACAGCCTACAACAAATAAACAAA
GCTTTTCTTACACAAAAATAAAGTCTGAGCCCTCTAGCCCAAGACTTGCCTCATCTCCAGTTCAGCCTAATATTGGGCCTTCTTTCCCTG
TGGGCCCTTTCCTATCTCAGTTTTCTTTCCCCCAAGATATCACCATGGTCCCTCAAGCTTCAGAGATCTTAGCTAAGATGTCTGAACTGG
TGCATCGGCGACTGAGGCATGGCAGTAGTAGCTACCCTCCCGTCATTTACAGCCCTTTGATGCCCAAGGGGGCTACTTGTTTTGAGTGTA
ACATAACATTCAATAATTTGGATAATTATCTAGTGCACAAAAAGCATTATTGCAGCAGCCGATGGCAGCAGATGGCTAAGTCCCCAGAGT
TCCCTAGTGTGTCAGAAAAGATGCCTGAAGCTTTGAGTCCCAACACTGGCCAAACCTCCATAAACCTTCTCAACCCAGCTGCTCATTCTG
CTGATCCTGAGAATCCACTTCTTCAAACATCTTGCATCAATTCTTCCACTGTCTTAGATTTAATTGGGCCAAATGGGAAGGGCCATGACA
AGGACTTTTCCACTCAAACTAAGAAGCTCTCCACCTCCAGTAACAATGATGACAAAATTAATGGAAAACCTGTTGATGTGAAAAATCCCA
GTGTCCCCTTAGTGGATGGGGAAAGTGACCCAAATAAGACTACCTGTGAAGCTTGCAACATTACCTTCAGCCGGCACGAAACATACATGG
TCCACAAACAGTATTACTGTGCTACACGCCACGACCCTCCACTGAAGAGGTCTGCTTCCAACAAAGTGCCTGCCATGCAGAGAACCATGC
GCACACGCAAGCGCAGAAAGATGTATGAGATGTGCCTACCTGAGCAGGAACAAAGGCCTCCACTGGTTCAGCAGAGATTTCTTGACGTAG
CCAACCTCAATAATCCTTGTACCTCCACTCAAGAACCCACAGAAGGGCTAGGAGAGTGCTACCACCCAAGATGTGATATCTTTCCAGGAA
TTGTCTCTAAACACTTGGAAACTTCTCTGACGATCAACAAGTGTGTTCCAGTTTCCAAATGTGATACTACTCATTCCAGTGTTTCCTGCC
TAGAGATGGACGTGCCCATAGATCTCAGCAAAAAGTGTTTATCTCAGTCTGAGCGGACGACCACGTCTCCCAAAAGGCTGCTGGACTATC
ACGAGTGCACTGTGTGCAAGATCAGTTTCAATAAGGTAGAAAACTATCTGGCCCACAAGCAGAATTTCTGCCCGGTTACTGCACATCAGC
GTAATGACCTGGGTCAACTGGACGGCAAAGTGTTTCCGAATCCAGAAAGCGAACGAAACAGCCCTGATGTCAGCTACGAAAGAAGCATAA
TAAAATGTGAGAAAAATGGGAATTTGAAGCAGCCTTCCCCCAATGGAAACTTATTTTCATCCCACCTAGCAACCCTGCAAGGCTTGAAGG
TCTTTAGTGAAGCTGCTCAGCTCATTGCTACAAAAGAAGAAAACAGACATTTGTTTCTTCCACAATGCCTTTACCCTGGAGCAATAAAGA
AAGCAAAAGGAGCCGACCAGCTTTCTCCATATTATGGAATCAAGCCAAGTGATTATATTTCTGGTTCTCTTGTCATCCATAACACTGACA
TCGAGCAAAGCAGAAATGCAGAAAATGAATCTCCTAAAGGCCAGGCTTCCTCAAATGGGTGTGCTGCGCTGAAGAAAGATTCTCTGCCAT
TGTTGCCCAAAAATCGAGGAATGGTAATAGTGAATGGTGGACTGAAACAAGATGAGAGACCTGCTGCCAACCCACAGCAAGAGAACATTT
CCCAGAATCCTCAGCACGAAGACGACCACAAATCTCCCTCGTGGATCTCTGAGAACCCATTAGCTGCCAATGAGAATGTCTCACCAGGAA
TTCCCTCAGCAGAGGAACAGTTGTCTAGTATAGCAAAAGGTGTGAATGGTTCCAGCCAGGCTCCAACCAGTGGGAAATATTGCCGGCTAT
GTGATATCCAGTTCAACAACCTTTCAAACTTTATAACTCACAAGAAGTTTTATTGCTCATCACATGCAGCAGAACATGTCAAATGAACTA

>93740_93740_2_TRAM1-ZFPM2_TRAM1_chr8_71506740_ENST00000262213_ZFPM2_chr8_106646473_ENST00000517361_length(amino acids)=1238AA_BP=227
MQRGREEQPAGGGGESVSSWEEQNRGGAPAGAGGGPTMAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTL
QYNVTLPATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISE
NYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKKKTKAQVPMVLTAGPKWLLDVTWQGVEDNKNNCIVYSKGGQLWC
TTTKAISEGEELIAFVVDFDSRLQAASQMTLTEGMYPARLLDSIQLLPQQAAMASILPTAIVNKDIFPCKSCGIWYRSERNLQAHLMYYC
SGRQREAAPVSEENEDSAHQISSLCPFPQCTKSFSNARALEMHLNSHSGVKMEEFLPPGASLKCTVCSYTADSVINFHQHLFSHLTQAAF
RCNHCHFGFQTQRELLQHQELHVPSGKLPRESDMEHSPSATEDSLQPATDLLTRSELPQSQKAMQTKDASSDTELDKCEKKTQLFLTNQR
PEIQPTTNKQSFSYTKIKSEPSSPRLASSPVQPNIGPSFPVGPFLSQFSFPQDITMVPQASEILAKMSELVHRRLRHGSSSYPPVIYSPL
MPKGATCFECNITFNNLDNYLVHKKHYCSSRWQQMAKSPEFPSVSEKMPEALSPNTGQTSINLLNPAAHSADPENPLLQTSCINSSTVLD
LIGPNGKGHDKDFSTQTKKLSTSSNNDDKINGKPVDVKNPSVPLVDGESDPNKTTCEACNITFSRHETYMVHKQYYCATRHDPPLKRSAS
NKVPAMQRTMRTRKRRKMYEMCLPEQEQRPPLVQQRFLDVANLNNPCTSTQEPTEGLGECYHPRCDIFPGIVSKHLETSLTINKCVPVSK
CDTTHSSVSCLEMDVPIDLSKKCLSQSERTTTSPKRLLDYHECTVCKISFNKVENYLAHKQNFCPVTAHQRNDLGQLDGKVFPNPESERN
SPDVSYERSIIKCEKNGNLKQPSPNGNLFSSHLATLQGLKVFSEAAQLIATKEENRHLFLPQCLYPGAIKKAKGADQLSPYYGIKPSDYI
SGSLVIHNTDIEQSRNAENESPKGQASSNGCAALKKDSLPLLPKNRGMVIVNGGLKQDERPAANPQQENISQNPQHEDDHKSPSWISENP

--------------------------------------------------------------
>93740_93740_3_TRAM1-ZFPM2_TRAM1_chr8_71506740_ENST00000262213_ZFPM2_chr8_106646473_ENST00000520492_length(transcript)=4108nt_BP=740nt
CGGGCGGCCCGGCGGCTGCGTACTGGCTGTGGGATGGGAAGTGAAGCCCCAGCGAGCGGCTGCAGCGGGGCCGTGAGGAGCAGCCAGCGG
GAGGCGGCGGCGAGTCGGTGAGCAGCTGGGAAGAGCAGAACCGGGGCGGAGCACCTGCAGGCGCGGGCGGCGGCCCCACCATGGCGATTC
GCAAGAAAAGCACCAAGAGCCCCCCAGTGCTGAGCCACGAATTCGTCCTGCAGAATCACGCGGACATCGTCTCCTGTGTGGCGATGGTCT
TCCTGCTGGGGCTCATGTTTGAGATAACGGCAAAAGCTTCTATCATTTTTGTTACTCTTCAGTACAATGTCACCCTCCCAGCAACAGAAG
AACAAGCTACTGAATCAGTGTCCCTTTATTACTATGGCATCAAAGATTTGGCTACTGTTTTCTTCTACATGCTAGTGGCGATAATTATTC
ATGCCGTAATTCAAGAGTATATGTTGGATAAAATTAACAGGCGAATGCACTTCTCCAAAACAAAACACAGCAAGTTTAATGAATCTGGTC
AGCTTAGTGCGTTCTACCTTTTTGCCTGTGTTTGGGGCACATTCATTCTCATCTCTGAAAACTACATCTCAGACCCAACTATCTTATGGA
GGGCTTATCCCCATAACCTGATGACATTTCAAATGAAGTTTTTCTACATATCACAGCTGGCTTACTGGCTTCATGCTTTTCCTGAACTCT
ACTTCCAGAAAACCAAAAAAAAGACAAAGGCTCAGGTCCCAATGGTGCTGACTGCTGGTCCCAAGTGGTTGCTGGATGTGACTTGGCAAG
GAGTGGAAGACAACAAAAACAACTGCATTGTGTACAGCAAAGGGGGTCAGCTTTGGTGTACAACTACGAAGGCCATCTCTGAGGGTGAAG
AGCTAATTGCCTTTGTGGTGGATTTTGACTCAAGGCTACAAGCTGCCAGTCAGATGACTCTCACAGAAGGGATGTACCCTGCACGCCTGC
TGGACTCAATTCAGCTGCTTCCTCAGCAAGCTGCCATGGCTTCTATTTTGCCCACAGCTATTGTCAATAAGGATATATTCCCTTGCAAGT
CCTGTGGCATCTGGTATCGGAGTGAGCGGAATCTGCAGGCCCATTTGATGTACTACTGCAGTGGGAGGCAAAGAGAAGCTGCTCCGGTGT
CAGAGGAAAATGAAGACAGTGCCCATCAGATTTCCAGCCTGTGCCCCTTCCCACAGTGCACCAAGAGCTTTTCAAATGCTCGAGCTCTAG
AAATGCACCTGAATTCACACAGTGGAGTGAAAATGGAAGAATTCCTGCCCCCTGGTGCTAGTCTAAAATGCACCGTCTGTAGCTACACTG
CTGATTCCGTGATCAACTTTCACCAACACCTGTTCTCCCATCTCACTCAAGCTGCCTTCCGATGTAATCACTGCCATTTCGGCTTCCAGA
CTCAGAGGGAGTTATTGCAGCACCAGGAGCTCCATGTCCCTAGCGGCAAACTTCCCAGAGAAAGTGACATGGAACACTCTCCAAGTGCAA
CTGAAGACAGCTTACAGCCAGCCACAGACTTATTGACCAGAAGCGAACTTCCCCAGAGCCAAAAGGCCATGCAGACTAAAGATGCGAGCT
CTGACACAGAGCTGGACAAGTGTGAGAAAAAGACTCAGCTCTTTCTCACGAACCAGAGACCAGAGATACAGCCTACAACAAATAAACAAA
GCTTTTCTTACACAAAAATAAAGTCTGAGCCCTCTAGCCCAAGACTTGCCTCATCTCCAGTTCAGCCTAATATTGGGCCTTCTTTCCCTG
TGGGCCCTTTCCTATCTCAGTTTTCTTTCCCCCAAGATATCACCATGGTCCCTCAAGCTTCAGAGATCTTAGCTAAGATGTCTGAACTGG
TGCATCGGCGACTGAGGCATGGCAGTAGTAGCTACCCTCCCGTCATTTACAGCCCTTTGATGCCCAAGGGGGCTACTTGTTTTGAGTGTA
ACATAACATTCAATAATTTGGATAATTATCTAGTGCACAAAAAGCATTATTGCAGCAGCCGATGGCAGCAGATGGCTAAGTCCCCAGAGT
TCCCTAGTGTGTCAGAAAAGATGCCTGAAGCTTTGAGTCCCAACACTGGCCAAACCTCCATAAACCTTCTCAACCCAGCTGCTCATTCTG
CTGATCCTGAGAATCCACTTCTTCAAACATCTTGCATCAATTCTTCCACTGTCTTAGATTTAATTGGGCCAAATGGGAAGGGCCATGACA
AGGACTTTTCCACTCAAACTAAGAAGCTCTCCACCTCCAGTAACAATGATGACAAAATTAATGGAAAACCTGTTGATGTGAAAAATCCCA
GTGTCCCCTTAGTGGATGGGGAAAGTGACCCAAATAAGACTACCTGTGAAGCTTGCAACATTACCTTCAGCCGGCACGAAACATACATGG
TCCACAAACAGTATTACTGTGCTACACGCCACGACCCTCCACTGAAGAGGTCTGCTTCCAACAAAGTGCCTGCCATGCAGAGAACCATGC
GCACACGCAAGCGCAGAAAGATGTATGAGATGTGCCTACCTGAGCAGGAACAAAGGCCTCCACTGGTTCAGCAGAGATTTCTTGACGTAG
CCAACCTCAATAATCCTTGTACCTCCACTCAAGAACCCACAGAAGGGCTAGGAGAGTGCTACCACCCAAGATGTGATATCTTTCCAGGAA
TTGTCTCTAAACACTTGGAAACTTCTCTGACGATCAACAAGTGTGTTCCAGTTTCCAAATGTGATACTACTCATTCCAGTGTTTCCTGCC
TAGAGATGGACGTGCCCATAGATCTCAGCAAAAAGTGTTTATCTCAGTCTGAGCGGACGACCACGTCTCCCAAAAGGCTGCTGGACTATC
ACGAGTGCACTGTGTGCAAGATCAGTTTCAATAAGGTAGAAAACTATCTGGCCCACAAGCAGAATTTCTGCCCGGTTACTGCACATCAGC
GTAATGACCTGGGTCAACTGGACGGCAAAGTGTTTCCGAATCCAGAAAGCGAACGAAACAGCCCTGATGTCAGCTACGAAAGAAGCATAA
TAAAATGTGAGAAAAATGGGAATTTGAAGCAGCCTTCCCCCAATGGAAACTTATTTTCATCCCACCTAGCAACCCTGCAAGGCTTGAAGG
TCTTTAGTGAAGCTGCTCAGCTCATTGCTACAAAAGAAGAAAACAGACATTTGTTTCTTCCACAATGCCTTTACCCTGGAGCAATAAAGA
AAGCAAAAGGAGCCGACCAGCTTTCTCCATATTATGGAATCAAGCCAAGTGATTATATTTCTGGTTCTCTTGTCATCCATAACACTGACA
TCGAGCAAAGCAGAAATGCAGAAAATGAATCTCCTAAAGGCCAGGCTTCCTCAAATGGGTGTGCTGCGCTGAAGAAAGATTCTCTGCCAT
TGTTGCCCAAAAATCGAGGAATGGTAATAGTGAATGGTGGACTGAAACAAGATGAGAGACCTGCTGCCAACCCACAGCAAGAGAACATTT
CCCAGAATCCTCAGCACGAAGACGACCACAAATCTCCCTCGTGGATCTCTGAGAACCCATTAGCTGCCAATGAGAATGTCTCACCAGGAA
TTCCCTCAGCAGAGGAACAGTTGTCTAGTATAGCAAAAGGTGTGAATGGTTCCAGCCAGGCTCCAACCAGTGGGAAATATTGCCGGCTAT
GTGATATCCAGTTCAACAACCTTTCAAACTTTATAACTCACAAGAAGTTTTATTGCTCATCACATGCAGCAGAACATGTCAAATGAACTA
ACTAAACATCAGTCACCTTTGGTATCAGTGTTTAGTATGTTGTTCTAACCAGTCCAGAAAAAAAAATAAGCTGTTTGAATTACATCTGGG
CAATCAGGAGATAATTCATTATGGCTGAGTTGAAGACTTAAGGTGTAATTTCATTACAGTCCATTAGTAAAGTGTATTATTGGTGCCATT
TTCAAAAAAATTAATTTATTTTACCAGCAGTATTCATAGCTGTGGTTATGTTATTTTTTATTTAAAAACTTTATATTAAAGTCATTTGTA

>93740_93740_3_TRAM1-ZFPM2_TRAM1_chr8_71506740_ENST00000262213_ZFPM2_chr8_106646473_ENST00000520492_length(amino acids)=1238AA_BP=227
MQRGREEQPAGGGGESVSSWEEQNRGGAPAGAGGGPTMAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTL
QYNVTLPATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISE
NYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKKKTKAQVPMVLTAGPKWLLDVTWQGVEDNKNNCIVYSKGGQLWC
TTTKAISEGEELIAFVVDFDSRLQAASQMTLTEGMYPARLLDSIQLLPQQAAMASILPTAIVNKDIFPCKSCGIWYRSERNLQAHLMYYC
SGRQREAAPVSEENEDSAHQISSLCPFPQCTKSFSNARALEMHLNSHSGVKMEEFLPPGASLKCTVCSYTADSVINFHQHLFSHLTQAAF
RCNHCHFGFQTQRELLQHQELHVPSGKLPRESDMEHSPSATEDSLQPATDLLTRSELPQSQKAMQTKDASSDTELDKCEKKTQLFLTNQR
PEIQPTTNKQSFSYTKIKSEPSSPRLASSPVQPNIGPSFPVGPFLSQFSFPQDITMVPQASEILAKMSELVHRRLRHGSSSYPPVIYSPL
MPKGATCFECNITFNNLDNYLVHKKHYCSSRWQQMAKSPEFPSVSEKMPEALSPNTGQTSINLLNPAAHSADPENPLLQTSCINSSTVLD
LIGPNGKGHDKDFSTQTKKLSTSSNNDDKINGKPVDVKNPSVPLVDGESDPNKTTCEACNITFSRHETYMVHKQYYCATRHDPPLKRSAS
NKVPAMQRTMRTRKRRKMYEMCLPEQEQRPPLVQQRFLDVANLNNPCTSTQEPTEGLGECYHPRCDIFPGIVSKHLETSLTINKCVPVSK
CDTTHSSVSCLEMDVPIDLSKKCLSQSERTTTSPKRLLDYHECTVCKISFNKVENYLAHKQNFCPVTAHQRNDLGQLDGKVFPNPESERN
SPDVSYERSIIKCEKNGNLKQPSPNGNLFSSHLATLQGLKVFSEAAQLIATKEENRHLFLPQCLYPGAIKKAKGADQLSPYYGIKPSDYI
SGSLVIHNTDIEQSRNAENESPKGQASSNGCAALKKDSLPLLPKNRGMVIVNGGLKQDERPAANPQQENISQNPQHEDDHKSPSWISENP

--------------------------------------------------------------
>93740_93740_4_TRAM1-ZFPM2_TRAM1_chr8_71506741_ENST00000262213_ZFPM2_chr8_106646474_ENST00000407775_length(transcript)=4770nt_BP=740nt
CGGGCGGCCCGGCGGCTGCGTACTGGCTGTGGGATGGGAAGTGAAGCCCCAGCGAGCGGCTGCAGCGGGGCCGTGAGGAGCAGCCAGCGG
GAGGCGGCGGCGAGTCGGTGAGCAGCTGGGAAGAGCAGAACCGGGGCGGAGCACCTGCAGGCGCGGGCGGCGGCCCCACCATGGCGATTC
GCAAGAAAAGCACCAAGAGCCCCCCAGTGCTGAGCCACGAATTCGTCCTGCAGAATCACGCGGACATCGTCTCCTGTGTGGCGATGGTCT
TCCTGCTGGGGCTCATGTTTGAGATAACGGCAAAAGCTTCTATCATTTTTGTTACTCTTCAGTACAATGTCACCCTCCCAGCAACAGAAG
AACAAGCTACTGAATCAGTGTCCCTTTATTACTATGGCATCAAAGATTTGGCTACTGTTTTCTTCTACATGCTAGTGGCGATAATTATTC
ATGCCGTAATTCAAGAGTATATGTTGGATAAAATTAACAGGCGAATGCACTTCTCCAAAACAAAACACAGCAAGTTTAATGAATCTGGTC
AGCTTAGTGCGTTCTACCTTTTTGCCTGTGTTTGGGGCACATTCATTCTCATCTCTGAAAACTACATCTCAGACCCAACTATCTTATGGA
GGGCTTATCCCCATAACCTGATGACATTTCAAATGAAGTTTTTCTACATATCACAGCTGGCTTACTGGCTTCATGCTTTTCCTGAACTCT
ACTTCCAGAAAACCAAAAAAAAGACAAAGGCTCAGGTCCCAATGGTGCTGACTGCTGGTCCCAAGTGGTTGCTGGATGTGACTTGGCAAG
GAGTGGAAGACAACAAAAACAACTGCATTGTGTACAGCAAAGGGGGTCAGCTTTGGTGTACAACTACGAAGGCCATCTCTGAGGGTGAAG
AGCTAATTGCCTTTGTGGTGGATTTTGACTCAAGGCTACAAGCTGCCAGTCAGATGACTCTCACAGAAGGGATGTACCCTGCACGCCTGC
TGGACTCAATTCAGCTGCTTCCTCAGCAAGCTGCCATGGCTTCTATTTTGCCCACAGCTATTGTCAATAAGGATATATTCCCTTGCAAGT
CCTGTGGCATCTGGTATCGGAGTGAGCGGAATCTGCAGGCCCATTTGATGTACTACTGCAGTGGGAGGCAAAGAGAAGCTGCTCCGGTGT
CAGAGGAAAATGAAGACAGTGCCCATCAGATTTCCAGCCTGTGCCCCTTCCCACAGTGCACCAAGAGCTTTTCAAATGCTCGAGCTCTAG
AAATGCACCTGAATTCACACAGTGGAGTGAAAATGGAAGAATTCCTGCCCCCTGGTGCTAGTCTAAAATGCACCGTCTGTAGCTACACTG
CTGATTCCGTGATCAACTTTCACCAACACCTGTTCTCCCATCTCACTCAAGCTGCCTTCCGATGTAATCACTGCCATTTCGGCTTCCAGA
CTCAGAGGGAGTTATTGCAGCACCAGGAGCTCCATGTCCCTAGCGGCAAACTTCCCAGAGAAAGTGACATGGAACACTCTCCAAGTGCAA
CTGAAGACAGCTTACAGCCAGCCACAGACTTATTGACCAGAAGCGAACTTCCCCAGAGCCAAAAGGCCATGCAGACTAAAGATGCGAGCT
CTGACACAGAGCTGGACAAGTGTGAGAAAAAGACTCAGCTCTTTCTCACGAACCAGAGACCAGAGATACAGCCTACAACAAATAAACAAA
GCTTTTCTTACACAAAAATAAAGTCTGAGCCCTCTAGCCCAAGACTTGCCTCATCTCCAGTTCAGCCTAATATTGGGCCTTCTTTCCCTG
TGGGCCCTTTCCTATCTCAGTTTTCTTTCCCCCAAGATATCACCATGGTCCCTCAAGCTTCAGAGATCTTAGCTAAGATGTCTGAACTGG
TGCATCGGCGACTGAGGCATGGCAGTAGTAGCTACCCTCCCGTCATTTACAGCCCTTTGATGCCCAAGGGGGCTACTTGTTTTGAGTGTA
ACATAACATTCAATAATTTGGATAATTATCTAGTGCACAAAAAGCATTATTGCAGCAGCCGATGGCAGCAGATGGCTAAGTCCCCAGAGT
TCCCTAGTGTGTCAGAAAAGATGCCTGAAGCTTTGAGTCCCAACACTGGCCAAACCTCCATAAACCTTCTCAACCCAGCTGCTCATTCTG
CTGATCCTGAGAATCCACTTCTTCAAACATCTTGCATCAATTCTTCCACTGTCTTAGATTTAATTGGGCCAAATGGGAAGGGCCATGACA
AGGACTTTTCCACTCAAACTAAGAAGCTCTCCACCTCCAGTAACAATGATGACAAAATTAATGGAAAACCTGTTGATGTGAAAAATCCCA
GTGTCCCCTTAGTGGATGGGGAAAGTGACCCAAATAAGACTACCTGTGAAGCTTGCAACATTACCTTCAGCCGGCACGAAACATACATGG
TCCACAAACAGTATTACTGTGCTACACGCCACGACCCTCCACTGAAGAGGTCTGCTTCCAACAAAGTGCCTGCCATGCAGAGAACCATGC
GCACACGCAAGCGCAGAAAGATGTATGAGATGTGCCTACCTGAGCAGGAACAAAGGCCTCCACTGGTTCAGCAGAGATTTCTTGACGTAG
CCAACCTCAATAATCCTTGTACCTCCACTCAAGAACCCACAGAAGGGCTAGGAGAGTGCTACCACCCAAGATGTGATATCTTTCCAGGAA
TTGTCTCTAAACACTTGGAAACTTCTCTGACGATCAACAAGTGTGTTCCAGTTTCCAAATGTGATACTACTCATTCCAGTGTTTCCTGCC
TAGAGATGGACGTGCCCATAGATCTCAGCAAAAAGTGTTTATCTCAGTCTGAGCGGACGACCACGTCTCCCAAAAGGCTGCTGGACTATC
ACGAGTGCACTGTGTGCAAGATCAGTTTCAATAAGGTAGAAAACTATCTGGCCCACAAGCAGAATTTCTGCCCGGTTACTGCACATCAGC
GTAATGACCTGGGTCAACTGGACGGCAAAGTGTTTCCGAATCCAGAAAGCGAACGAAACAGCCCTGATGTCAGCTACGAAAGAAGCATAA
TAAAATGTGAGAAAAATGGGAATTTGAAGCAGCCTTCCCCCAATGGAAACTTATTTTCATCCCACCTAGCAACCCTGCAAGGCTTGAAGG
TCTTTAGTGAAGCTGCTCAGCTCATTGCTACAAAAGAAGAAAACAGACATTTGTTTCTTCCACAATGCCTTTACCCTGGAGCAATAAAGA
AAGCAAAAGGAGCCGACCAGCTTTCTCCATATTATGGAATCAAGCCAAGTGATTATATTTCTGGTTCTCTTGTCATCCATAACACTGACA
TCGAGCAAAGCAGAAATGCAGAAAATGAATCTCCTAAAGGCCAGGCTTCCTCAAATGGGTGTGCTGCGCTGAAGAAAGATTCTCTGCCAT
TGTTGCCCAAAAATCGAGGAATGGTAATAGTGAATGGTGGACTGAAACAAGATGAGAGACCTGCTGCCAACCCACAGCAAGAGAACATTT
CCCAGAATCCTCAGCACGAAGACGACCACAAATCTCCCTCGTGGATCTCTGAGAACCCATTAGCTGCCAATGAGAATGTCTCACCAGGAA
TTCCCTCAGCAGAGGAACAGTTGTCTAGTATAGCAAAAGGTGTGAATGGTTCCAGCCAGGCTCCAACCAGTGGGAAATATTGCCGGCTAT
GTGATATCCAGTTCAACAACCTTTCAAACTTTATAACTCACAAGAAGTTTTATTGCTCATCACATGCAGCAGAACATGTCAAATGAACTA
ACTAAACATCAGTCACCTTTGGTATCAGTGTTTAGTATGTTGTTCTAACCAGTCCAGAAAAAAAAATAAGCTGTTTGAATTACATCTGGG
CAATCAGGAGATAATTCATTATGGCTGAGTTGAAGACTTAAGGTGTAATTTCATTACAGTCCATTAGTAAAGTGTATTATTGGTGCCATT
TTCAAAAAAATTAATTTATTTTACCAGCAGTATTCATAGCTGTGGTTATGTTATTTTTTATTTAAAAACTTTATATTAAAGTCATTTGTA
ATGTTATTGTATAGTTATTGTGTAGCACATATGGTTTGCACTGTATAGTAGCTTTTAAAGAAAATAGTCACAATACAGAAAAGCATTTTA
GAAATAGCTTCAAAAGCACTTGTGTATCTTGATTTTTTCTTATATGCTGTTGCAGATATATGTATATGCTAAAATATAACTTGCAAAGAT
GTTCTAAATACACATGCTATAAGTTCGCCTTAAGATTTCAATTCTTGGATAATCAGGCTCTGTTTGCACTTTATATTTTAGCAGATACAG
TCTCTTAGTCACTAGGCTTTGCATTTGTATGTAGCTGTATGTTTCCGTCCATTTTCTTAATCCTGAACCTGTATGTTAAATGAAGATGGC
AATTTTTTTCTTGTATAGTACTTGTATTTTCTTTCGCTGATGCAGCTCTGTCTCAATTTTTAAACCTTTGCTGTTAAATGCAATACTTTA
TAAAGAATGAACAAAATTACTGGAAGCAGTATTGTAAGTAATGAGGTAGTATTAATCAGTTTTATCTTTTGAAAGGCACAGTCTAAATCG
AAACCCTAAACTCAATGCTGCAAGTATGAATTTAATTCATATATAAGATCTATTTAAATATAAGAGTAGCAATACTGCACCTGGTGATCA
CAAAGATAATGTTCTACTTCTGATAGAAATAATTTCTCAACAAATGTTGTTACTATGCATGTATATGGATGGAATAAAATTCCAGATTGT

>93740_93740_4_TRAM1-ZFPM2_TRAM1_chr8_71506741_ENST00000262213_ZFPM2_chr8_106646474_ENST00000407775_length(amino acids)=1238AA_BP=227
MQRGREEQPAGGGGESVSSWEEQNRGGAPAGAGGGPTMAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTL
QYNVTLPATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISE
NYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKKKTKAQVPMVLTAGPKWLLDVTWQGVEDNKNNCIVYSKGGQLWC
TTTKAISEGEELIAFVVDFDSRLQAASQMTLTEGMYPARLLDSIQLLPQQAAMASILPTAIVNKDIFPCKSCGIWYRSERNLQAHLMYYC
SGRQREAAPVSEENEDSAHQISSLCPFPQCTKSFSNARALEMHLNSHSGVKMEEFLPPGASLKCTVCSYTADSVINFHQHLFSHLTQAAF
RCNHCHFGFQTQRELLQHQELHVPSGKLPRESDMEHSPSATEDSLQPATDLLTRSELPQSQKAMQTKDASSDTELDKCEKKTQLFLTNQR
PEIQPTTNKQSFSYTKIKSEPSSPRLASSPVQPNIGPSFPVGPFLSQFSFPQDITMVPQASEILAKMSELVHRRLRHGSSSYPPVIYSPL
MPKGATCFECNITFNNLDNYLVHKKHYCSSRWQQMAKSPEFPSVSEKMPEALSPNTGQTSINLLNPAAHSADPENPLLQTSCINSSTVLD
LIGPNGKGHDKDFSTQTKKLSTSSNNDDKINGKPVDVKNPSVPLVDGESDPNKTTCEACNITFSRHETYMVHKQYYCATRHDPPLKRSAS
NKVPAMQRTMRTRKRRKMYEMCLPEQEQRPPLVQQRFLDVANLNNPCTSTQEPTEGLGECYHPRCDIFPGIVSKHLETSLTINKCVPVSK
CDTTHSSVSCLEMDVPIDLSKKCLSQSERTTTSPKRLLDYHECTVCKISFNKVENYLAHKQNFCPVTAHQRNDLGQLDGKVFPNPESERN
SPDVSYERSIIKCEKNGNLKQPSPNGNLFSSHLATLQGLKVFSEAAQLIATKEENRHLFLPQCLYPGAIKKAKGADQLSPYYGIKPSDYI
SGSLVIHNTDIEQSRNAENESPKGQASSNGCAALKKDSLPLLPKNRGMVIVNGGLKQDERPAANPQQENISQNPQHEDDHKSPSWISENP

--------------------------------------------------------------
>93740_93740_5_TRAM1-ZFPM2_TRAM1_chr8_71506741_ENST00000262213_ZFPM2_chr8_106646474_ENST00000517361_length(transcript)=3835nt_BP=740nt
CGGGCGGCCCGGCGGCTGCGTACTGGCTGTGGGATGGGAAGTGAAGCCCCAGCGAGCGGCTGCAGCGGGGCCGTGAGGAGCAGCCAGCGG
GAGGCGGCGGCGAGTCGGTGAGCAGCTGGGAAGAGCAGAACCGGGGCGGAGCACCTGCAGGCGCGGGCGGCGGCCCCACCATGGCGATTC
GCAAGAAAAGCACCAAGAGCCCCCCAGTGCTGAGCCACGAATTCGTCCTGCAGAATCACGCGGACATCGTCTCCTGTGTGGCGATGGTCT
TCCTGCTGGGGCTCATGTTTGAGATAACGGCAAAAGCTTCTATCATTTTTGTTACTCTTCAGTACAATGTCACCCTCCCAGCAACAGAAG
AACAAGCTACTGAATCAGTGTCCCTTTATTACTATGGCATCAAAGATTTGGCTACTGTTTTCTTCTACATGCTAGTGGCGATAATTATTC
ATGCCGTAATTCAAGAGTATATGTTGGATAAAATTAACAGGCGAATGCACTTCTCCAAAACAAAACACAGCAAGTTTAATGAATCTGGTC
AGCTTAGTGCGTTCTACCTTTTTGCCTGTGTTTGGGGCACATTCATTCTCATCTCTGAAAACTACATCTCAGACCCAACTATCTTATGGA
GGGCTTATCCCCATAACCTGATGACATTTCAAATGAAGTTTTTCTACATATCACAGCTGGCTTACTGGCTTCATGCTTTTCCTGAACTCT
ACTTCCAGAAAACCAAAAAAAAGACAAAGGCTCAGGTCCCAATGGTGCTGACTGCTGGTCCCAAGTGGTTGCTGGATGTGACTTGGCAAG
GAGTGGAAGACAACAAAAACAACTGCATTGTGTACAGCAAAGGGGGTCAGCTTTGGTGTACAACTACGAAGGCCATCTCTGAGGGTGAAG
AGCTAATTGCCTTTGTGGTGGATTTTGACTCAAGGCTACAAGCTGCCAGTCAGATGACTCTCACAGAAGGGATGTACCCTGCACGCCTGC
TGGACTCAATTCAGCTGCTTCCTCAGCAAGCTGCCATGGCTTCTATTTTGCCCACAGCTATTGTCAATAAGGATATATTCCCTTGCAAGT
CCTGTGGCATCTGGTATCGGAGTGAGCGGAATCTGCAGGCCCATTTGATGTACTACTGCAGTGGGAGGCAAAGAGAAGCTGCTCCGGTGT
CAGAGGAAAATGAAGACAGTGCCCATCAGATTTCCAGCCTGTGCCCCTTCCCACAGTGCACCAAGAGCTTTTCAAATGCTCGAGCTCTAG
AAATGCACCTGAATTCACACAGTGGAGTGAAAATGGAAGAATTCCTGCCCCCTGGTGCTAGTCTAAAATGCACCGTCTGTAGCTACACTG
CTGATTCCGTGATCAACTTTCACCAACACCTGTTCTCCCATCTCACTCAAGCTGCCTTCCGATGTAATCACTGCCATTTCGGCTTCCAGA
CTCAGAGGGAGTTATTGCAGCACCAGGAGCTCCATGTCCCTAGCGGCAAACTTCCCAGAGAAAGTGACATGGAACACTCTCCAAGTGCAA
CTGAAGACAGCTTACAGCCAGCCACAGACTTATTGACCAGAAGCGAACTTCCCCAGAGCCAAAAGGCCATGCAGACTAAAGATGCGAGCT
CTGACACAGAGCTGGACAAGTGTGAGAAAAAGACTCAGCTCTTTCTCACGAACCAGAGACCAGAGATACAGCCTACAACAAATAAACAAA
GCTTTTCTTACACAAAAATAAAGTCTGAGCCCTCTAGCCCAAGACTTGCCTCATCTCCAGTTCAGCCTAATATTGGGCCTTCTTTCCCTG
TGGGCCCTTTCCTATCTCAGTTTTCTTTCCCCCAAGATATCACCATGGTCCCTCAAGCTTCAGAGATCTTAGCTAAGATGTCTGAACTGG
TGCATCGGCGACTGAGGCATGGCAGTAGTAGCTACCCTCCCGTCATTTACAGCCCTTTGATGCCCAAGGGGGCTACTTGTTTTGAGTGTA
ACATAACATTCAATAATTTGGATAATTATCTAGTGCACAAAAAGCATTATTGCAGCAGCCGATGGCAGCAGATGGCTAAGTCCCCAGAGT
TCCCTAGTGTGTCAGAAAAGATGCCTGAAGCTTTGAGTCCCAACACTGGCCAAACCTCCATAAACCTTCTCAACCCAGCTGCTCATTCTG
CTGATCCTGAGAATCCACTTCTTCAAACATCTTGCATCAATTCTTCCACTGTCTTAGATTTAATTGGGCCAAATGGGAAGGGCCATGACA
AGGACTTTTCCACTCAAACTAAGAAGCTCTCCACCTCCAGTAACAATGATGACAAAATTAATGGAAAACCTGTTGATGTGAAAAATCCCA
GTGTCCCCTTAGTGGATGGGGAAAGTGACCCAAATAAGACTACCTGTGAAGCTTGCAACATTACCTTCAGCCGGCACGAAACATACATGG
TCCACAAACAGTATTACTGTGCTACACGCCACGACCCTCCACTGAAGAGGTCTGCTTCCAACAAAGTGCCTGCCATGCAGAGAACCATGC
GCACACGCAAGCGCAGAAAGATGTATGAGATGTGCCTACCTGAGCAGGAACAAAGGCCTCCACTGGTTCAGCAGAGATTTCTTGACGTAG
CCAACCTCAATAATCCTTGTACCTCCACTCAAGAACCCACAGAAGGGCTAGGAGAGTGCTACCACCCAAGATGTGATATCTTTCCAGGAA
TTGTCTCTAAACACTTGGAAACTTCTCTGACGATCAACAAGTGTGTTCCAGTTTCCAAATGTGATACTACTCATTCCAGTGTTTCCTGCC
TAGAGATGGACGTGCCCATAGATCTCAGCAAAAAGTGTTTATCTCAGTCTGAGCGGACGACCACGTCTCCCAAAAGGCTGCTGGACTATC
ACGAGTGCACTGTGTGCAAGATCAGTTTCAATAAGGTAGAAAACTATCTGGCCCACAAGCAGAATTTCTGCCCGGTTACTGCACATCAGC
GTAATGACCTGGGTCAACTGGACGGCAAAGTGTTTCCGAATCCAGAAAGCGAACGAAACAGCCCTGATGTCAGCTACGAAAGAAGCATAA
TAAAATGTGAGAAAAATGGGAATTTGAAGCAGCCTTCCCCCAATGGAAACTTATTTTCATCCCACCTAGCAACCCTGCAAGGCTTGAAGG
TCTTTAGTGAAGCTGCTCAGCTCATTGCTACAAAAGAAGAAAACAGACATTTGTTTCTTCCACAATGCCTTTACCCTGGAGCAATAAAGA
AAGCAAAAGGAGCCGACCAGCTTTCTCCATATTATGGAATCAAGCCAAGTGATTATATTTCTGGTTCTCTTGTCATCCATAACACTGACA
TCGAGCAAAGCAGAAATGCAGAAAATGAATCTCCTAAAGGCCAGGCTTCCTCAAATGGGTGTGCTGCGCTGAAGAAAGATTCTCTGCCAT
TGTTGCCCAAAAATCGAGGAATGGTAATAGTGAATGGTGGACTGAAACAAGATGAGAGACCTGCTGCCAACCCACAGCAAGAGAACATTT
CCCAGAATCCTCAGCACGAAGACGACCACAAATCTCCCTCGTGGATCTCTGAGAACCCATTAGCTGCCAATGAGAATGTCTCACCAGGAA
TTCCCTCAGCAGAGGAACAGTTGTCTAGTATAGCAAAAGGTGTGAATGGTTCCAGCCAGGCTCCAACCAGTGGGAAATATTGCCGGCTAT
GTGATATCCAGTTCAACAACCTTTCAAACTTTATAACTCACAAGAAGTTTTATTGCTCATCACATGCAGCAGAACATGTCAAATGAACTA

>93740_93740_5_TRAM1-ZFPM2_TRAM1_chr8_71506741_ENST00000262213_ZFPM2_chr8_106646474_ENST00000517361_length(amino acids)=1238AA_BP=227
MQRGREEQPAGGGGESVSSWEEQNRGGAPAGAGGGPTMAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTL
QYNVTLPATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISE
NYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKKKTKAQVPMVLTAGPKWLLDVTWQGVEDNKNNCIVYSKGGQLWC
TTTKAISEGEELIAFVVDFDSRLQAASQMTLTEGMYPARLLDSIQLLPQQAAMASILPTAIVNKDIFPCKSCGIWYRSERNLQAHLMYYC
SGRQREAAPVSEENEDSAHQISSLCPFPQCTKSFSNARALEMHLNSHSGVKMEEFLPPGASLKCTVCSYTADSVINFHQHLFSHLTQAAF
RCNHCHFGFQTQRELLQHQELHVPSGKLPRESDMEHSPSATEDSLQPATDLLTRSELPQSQKAMQTKDASSDTELDKCEKKTQLFLTNQR
PEIQPTTNKQSFSYTKIKSEPSSPRLASSPVQPNIGPSFPVGPFLSQFSFPQDITMVPQASEILAKMSELVHRRLRHGSSSYPPVIYSPL
MPKGATCFECNITFNNLDNYLVHKKHYCSSRWQQMAKSPEFPSVSEKMPEALSPNTGQTSINLLNPAAHSADPENPLLQTSCINSSTVLD
LIGPNGKGHDKDFSTQTKKLSTSSNNDDKINGKPVDVKNPSVPLVDGESDPNKTTCEACNITFSRHETYMVHKQYYCATRHDPPLKRSAS
NKVPAMQRTMRTRKRRKMYEMCLPEQEQRPPLVQQRFLDVANLNNPCTSTQEPTEGLGECYHPRCDIFPGIVSKHLETSLTINKCVPVSK
CDTTHSSVSCLEMDVPIDLSKKCLSQSERTTTSPKRLLDYHECTVCKISFNKVENYLAHKQNFCPVTAHQRNDLGQLDGKVFPNPESERN
SPDVSYERSIIKCEKNGNLKQPSPNGNLFSSHLATLQGLKVFSEAAQLIATKEENRHLFLPQCLYPGAIKKAKGADQLSPYYGIKPSDYI
SGSLVIHNTDIEQSRNAENESPKGQASSNGCAALKKDSLPLLPKNRGMVIVNGGLKQDERPAANPQQENISQNPQHEDDHKSPSWISENP

--------------------------------------------------------------
>93740_93740_6_TRAM1-ZFPM2_TRAM1_chr8_71506741_ENST00000262213_ZFPM2_chr8_106646474_ENST00000520492_length(transcript)=4108nt_BP=740nt
CGGGCGGCCCGGCGGCTGCGTACTGGCTGTGGGATGGGAAGTGAAGCCCCAGCGAGCGGCTGCAGCGGGGCCGTGAGGAGCAGCCAGCGG
GAGGCGGCGGCGAGTCGGTGAGCAGCTGGGAAGAGCAGAACCGGGGCGGAGCACCTGCAGGCGCGGGCGGCGGCCCCACCATGGCGATTC
GCAAGAAAAGCACCAAGAGCCCCCCAGTGCTGAGCCACGAATTCGTCCTGCAGAATCACGCGGACATCGTCTCCTGTGTGGCGATGGTCT
TCCTGCTGGGGCTCATGTTTGAGATAACGGCAAAAGCTTCTATCATTTTTGTTACTCTTCAGTACAATGTCACCCTCCCAGCAACAGAAG
AACAAGCTACTGAATCAGTGTCCCTTTATTACTATGGCATCAAAGATTTGGCTACTGTTTTCTTCTACATGCTAGTGGCGATAATTATTC
ATGCCGTAATTCAAGAGTATATGTTGGATAAAATTAACAGGCGAATGCACTTCTCCAAAACAAAACACAGCAAGTTTAATGAATCTGGTC
AGCTTAGTGCGTTCTACCTTTTTGCCTGTGTTTGGGGCACATTCATTCTCATCTCTGAAAACTACATCTCAGACCCAACTATCTTATGGA
GGGCTTATCCCCATAACCTGATGACATTTCAAATGAAGTTTTTCTACATATCACAGCTGGCTTACTGGCTTCATGCTTTTCCTGAACTCT
ACTTCCAGAAAACCAAAAAAAAGACAAAGGCTCAGGTCCCAATGGTGCTGACTGCTGGTCCCAAGTGGTTGCTGGATGTGACTTGGCAAG
GAGTGGAAGACAACAAAAACAACTGCATTGTGTACAGCAAAGGGGGTCAGCTTTGGTGTACAACTACGAAGGCCATCTCTGAGGGTGAAG
AGCTAATTGCCTTTGTGGTGGATTTTGACTCAAGGCTACAAGCTGCCAGTCAGATGACTCTCACAGAAGGGATGTACCCTGCACGCCTGC
TGGACTCAATTCAGCTGCTTCCTCAGCAAGCTGCCATGGCTTCTATTTTGCCCACAGCTATTGTCAATAAGGATATATTCCCTTGCAAGT
CCTGTGGCATCTGGTATCGGAGTGAGCGGAATCTGCAGGCCCATTTGATGTACTACTGCAGTGGGAGGCAAAGAGAAGCTGCTCCGGTGT
CAGAGGAAAATGAAGACAGTGCCCATCAGATTTCCAGCCTGTGCCCCTTCCCACAGTGCACCAAGAGCTTTTCAAATGCTCGAGCTCTAG
AAATGCACCTGAATTCACACAGTGGAGTGAAAATGGAAGAATTCCTGCCCCCTGGTGCTAGTCTAAAATGCACCGTCTGTAGCTACACTG
CTGATTCCGTGATCAACTTTCACCAACACCTGTTCTCCCATCTCACTCAAGCTGCCTTCCGATGTAATCACTGCCATTTCGGCTTCCAGA
CTCAGAGGGAGTTATTGCAGCACCAGGAGCTCCATGTCCCTAGCGGCAAACTTCCCAGAGAAAGTGACATGGAACACTCTCCAAGTGCAA
CTGAAGACAGCTTACAGCCAGCCACAGACTTATTGACCAGAAGCGAACTTCCCCAGAGCCAAAAGGCCATGCAGACTAAAGATGCGAGCT
CTGACACAGAGCTGGACAAGTGTGAGAAAAAGACTCAGCTCTTTCTCACGAACCAGAGACCAGAGATACAGCCTACAACAAATAAACAAA
GCTTTTCTTACACAAAAATAAAGTCTGAGCCCTCTAGCCCAAGACTTGCCTCATCTCCAGTTCAGCCTAATATTGGGCCTTCTTTCCCTG
TGGGCCCTTTCCTATCTCAGTTTTCTTTCCCCCAAGATATCACCATGGTCCCTCAAGCTTCAGAGATCTTAGCTAAGATGTCTGAACTGG
TGCATCGGCGACTGAGGCATGGCAGTAGTAGCTACCCTCCCGTCATTTACAGCCCTTTGATGCCCAAGGGGGCTACTTGTTTTGAGTGTA
ACATAACATTCAATAATTTGGATAATTATCTAGTGCACAAAAAGCATTATTGCAGCAGCCGATGGCAGCAGATGGCTAAGTCCCCAGAGT
TCCCTAGTGTGTCAGAAAAGATGCCTGAAGCTTTGAGTCCCAACACTGGCCAAACCTCCATAAACCTTCTCAACCCAGCTGCTCATTCTG
CTGATCCTGAGAATCCACTTCTTCAAACATCTTGCATCAATTCTTCCACTGTCTTAGATTTAATTGGGCCAAATGGGAAGGGCCATGACA
AGGACTTTTCCACTCAAACTAAGAAGCTCTCCACCTCCAGTAACAATGATGACAAAATTAATGGAAAACCTGTTGATGTGAAAAATCCCA
GTGTCCCCTTAGTGGATGGGGAAAGTGACCCAAATAAGACTACCTGTGAAGCTTGCAACATTACCTTCAGCCGGCACGAAACATACATGG
TCCACAAACAGTATTACTGTGCTACACGCCACGACCCTCCACTGAAGAGGTCTGCTTCCAACAAAGTGCCTGCCATGCAGAGAACCATGC
GCACACGCAAGCGCAGAAAGATGTATGAGATGTGCCTACCTGAGCAGGAACAAAGGCCTCCACTGGTTCAGCAGAGATTTCTTGACGTAG
CCAACCTCAATAATCCTTGTACCTCCACTCAAGAACCCACAGAAGGGCTAGGAGAGTGCTACCACCCAAGATGTGATATCTTTCCAGGAA
TTGTCTCTAAACACTTGGAAACTTCTCTGACGATCAACAAGTGTGTTCCAGTTTCCAAATGTGATACTACTCATTCCAGTGTTTCCTGCC
TAGAGATGGACGTGCCCATAGATCTCAGCAAAAAGTGTTTATCTCAGTCTGAGCGGACGACCACGTCTCCCAAAAGGCTGCTGGACTATC
ACGAGTGCACTGTGTGCAAGATCAGTTTCAATAAGGTAGAAAACTATCTGGCCCACAAGCAGAATTTCTGCCCGGTTACTGCACATCAGC
GTAATGACCTGGGTCAACTGGACGGCAAAGTGTTTCCGAATCCAGAAAGCGAACGAAACAGCCCTGATGTCAGCTACGAAAGAAGCATAA
TAAAATGTGAGAAAAATGGGAATTTGAAGCAGCCTTCCCCCAATGGAAACTTATTTTCATCCCACCTAGCAACCCTGCAAGGCTTGAAGG
TCTTTAGTGAAGCTGCTCAGCTCATTGCTACAAAAGAAGAAAACAGACATTTGTTTCTTCCACAATGCCTTTACCCTGGAGCAATAAAGA
AAGCAAAAGGAGCCGACCAGCTTTCTCCATATTATGGAATCAAGCCAAGTGATTATATTTCTGGTTCTCTTGTCATCCATAACACTGACA
TCGAGCAAAGCAGAAATGCAGAAAATGAATCTCCTAAAGGCCAGGCTTCCTCAAATGGGTGTGCTGCGCTGAAGAAAGATTCTCTGCCAT
TGTTGCCCAAAAATCGAGGAATGGTAATAGTGAATGGTGGACTGAAACAAGATGAGAGACCTGCTGCCAACCCACAGCAAGAGAACATTT
CCCAGAATCCTCAGCACGAAGACGACCACAAATCTCCCTCGTGGATCTCTGAGAACCCATTAGCTGCCAATGAGAATGTCTCACCAGGAA
TTCCCTCAGCAGAGGAACAGTTGTCTAGTATAGCAAAAGGTGTGAATGGTTCCAGCCAGGCTCCAACCAGTGGGAAATATTGCCGGCTAT
GTGATATCCAGTTCAACAACCTTTCAAACTTTATAACTCACAAGAAGTTTTATTGCTCATCACATGCAGCAGAACATGTCAAATGAACTA
ACTAAACATCAGTCACCTTTGGTATCAGTGTTTAGTATGTTGTTCTAACCAGTCCAGAAAAAAAAATAAGCTGTTTGAATTACATCTGGG
CAATCAGGAGATAATTCATTATGGCTGAGTTGAAGACTTAAGGTGTAATTTCATTACAGTCCATTAGTAAAGTGTATTATTGGTGCCATT
TTCAAAAAAATTAATTTATTTTACCAGCAGTATTCATAGCTGTGGTTATGTTATTTTTTATTTAAAAACTTTATATTAAAGTCATTTGTA

>93740_93740_6_TRAM1-ZFPM2_TRAM1_chr8_71506741_ENST00000262213_ZFPM2_chr8_106646474_ENST00000520492_length(amino acids)=1238AA_BP=227
MQRGREEQPAGGGGESVSSWEEQNRGGAPAGAGGGPTMAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTL
QYNVTLPATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISE
NYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKKKTKAQVPMVLTAGPKWLLDVTWQGVEDNKNNCIVYSKGGQLWC
TTTKAISEGEELIAFVVDFDSRLQAASQMTLTEGMYPARLLDSIQLLPQQAAMASILPTAIVNKDIFPCKSCGIWYRSERNLQAHLMYYC
SGRQREAAPVSEENEDSAHQISSLCPFPQCTKSFSNARALEMHLNSHSGVKMEEFLPPGASLKCTVCSYTADSVINFHQHLFSHLTQAAF
RCNHCHFGFQTQRELLQHQELHVPSGKLPRESDMEHSPSATEDSLQPATDLLTRSELPQSQKAMQTKDASSDTELDKCEKKTQLFLTNQR
PEIQPTTNKQSFSYTKIKSEPSSPRLASSPVQPNIGPSFPVGPFLSQFSFPQDITMVPQASEILAKMSELVHRRLRHGSSSYPPVIYSPL
MPKGATCFECNITFNNLDNYLVHKKHYCSSRWQQMAKSPEFPSVSEKMPEALSPNTGQTSINLLNPAAHSADPENPLLQTSCINSSTVLD
LIGPNGKGHDKDFSTQTKKLSTSSNNDDKINGKPVDVKNPSVPLVDGESDPNKTTCEACNITFSRHETYMVHKQYYCATRHDPPLKRSAS
NKVPAMQRTMRTRKRRKMYEMCLPEQEQRPPLVQQRFLDVANLNNPCTSTQEPTEGLGECYHPRCDIFPGIVSKHLETSLTINKCVPVSK
CDTTHSSVSCLEMDVPIDLSKKCLSQSERTTTSPKRLLDYHECTVCKISFNKVENYLAHKQNFCPVTAHQRNDLGQLDGKVFPNPESERN
SPDVSYERSIIKCEKNGNLKQPSPNGNLFSSHLATLQGLKVFSEAAQLIATKEENRHLFLPQCLYPGAIKKAKGADQLSPYYGIKPSDYI
SGSLVIHNTDIEQSRNAENESPKGQASSNGCAALKKDSLPLLPKNRGMVIVNGGLKQDERPAANPQQENISQNPQHEDDHKSPSWISENP

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Fusion Gene PPI Analysis for TRAM1-ZFPM2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneZFPM2chr8:71506740chr8:106646473ENST0000040777538829_835140.01152.0CTBP2
TgeneZFPM2chr8:71506741chr8:106646474ENST0000040777538829_835140.01152.0CTBP2


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TRAM1-ZFPM2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TRAM1-ZFPM2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource