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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TRIM24-KIAA1324L (FusionGDB2 ID:94006)

Fusion Gene Summary for TRIM24-KIAA1324L

check button Fusion gene summary
Fusion gene informationFusion gene name: TRIM24-KIAA1324L
Fusion gene ID: 94006
HgeneTgene
Gene symbol

TRIM24

KIAA1324L

Gene ID

8805

222223

Gene nametripartite motif containing 24endosome-lysosome associated apoptosis and autophagy regulator family member 2
SynonymsPTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1EIG121L|KIAA1324L
Cytomap

7q33-q34

7q21.12

Type of geneprotein-codingprotein-coding
Descriptiontranscription intermediary factor 1-alphaE3 ubiquitin-protein ligase TRIM24RING finger protein 82RING-type E3 ubiquitin transferase TIF1-alphaTIF1-alphatranscriptional intermediary factor 1UPF0577 protein KIAA1324-likeEIG121-likeKIAA1324 likeestrogen-induced gene 121-like protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000343526, ENST00000415680, 
ENST00000497516, 		ENST00000297222, 
ENST00000416314, ENST00000444627, 
ENST00000490995, ENST00000450689, 
Fusion gene scores* DoF score10 X 9 X 7=6305 X 5 X 3=75
# samples 105
** MAII scorelog2(10/630*10)=-2.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TRIM24 [Title/Abstract] AND KIAA1324L [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTRIM24(138145657)-KIAA1324L(86577238), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTRIM24

GO:0016567

protein ubiquitination

19556538

HgeneTRIM24

GO:0071391

cellular response to estrogen stimulus

21164480


check buttonFusion gene breakpoints across TRIM24 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across KIAA1324L (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-44-A479-01ATRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-


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Fusion Gene ORF analysis for TRIM24-KIAA1324L

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000343526ENST00000297222TRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-
5CDS-intronENST00000343526ENST00000416314TRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-
5CDS-intronENST00000343526ENST00000444627TRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-
5CDS-intronENST00000343526ENST00000490995TRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-
5CDS-intronENST00000415680ENST00000297222TRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-
5CDS-intronENST00000415680ENST00000416314TRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-
5CDS-intronENST00000415680ENST00000444627TRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-
5CDS-intronENST00000415680ENST00000490995TRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-
In-frameENST00000343526ENST00000450689TRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-
In-frameENST00000415680ENST00000450689TRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-
intron-3CDSENST00000497516ENST00000450689TRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-
intron-intronENST00000497516ENST00000297222TRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-
intron-intronENST00000497516ENST00000416314TRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-
intron-intronENST00000497516ENST00000444627TRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-
intron-intronENST00000497516ENST00000490995TRIM24chr7

138145657

+KIAA1324Lchr7

86577238

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000343526TRIM24chr7138145657+ENST00000450689KIAA1324Lchr786577238-69245799233581088
ENST00000415680TRIM24chr7138145657+ENST00000450689KIAA1324Lchr786577238-682347811432571047

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000343526ENST00000450689TRIM24chr7138145657+KIAA1324Lchr786577238-7.65E-050.99992347
ENST00000415680ENST00000450689TRIM24chr7138145657+KIAA1324Lchr786577238-6.75E-050.9999325

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Fusion Genomic Features for TRIM24-KIAA1324L


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TRIM24-KIAA1324L


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:138145657/chr7:86577238)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRIM24chr7:138145657chr7:86577238ENST00000343526+1199_151211051.0Compositional biasNote=Poly-Ala
HgeneTRIM24chr7:138145657chr7:86577238ENST00000415680+1199_151211017.0Compositional biasNote=Poly-Ala
HgeneTRIM24chr7:138145657chr7:86577238ENST00000343526+11956_821211051.0Zinc fingerRING-type
HgeneTRIM24chr7:138145657chr7:86577238ENST00000415680+11956_821211017.0Zinc fingerRING-type
TgeneKIAA1324Lchr7:138145657chr7:86577238ENST00000297222018672_8770790.0DomainMRH
TgeneKIAA1324Lchr7:138145657chr7:86577238ENST00000416314021672_8770863.0DomainMRH
TgeneKIAA1324Lchr7:138145657chr7:86577238ENST00000450689122672_8771031030.0DomainMRH
TgeneKIAA1324Lchr7:138145657chr7:86577238ENST0000029722201848_9290790.0Topological domainExtracellular
TgeneKIAA1324Lchr7:138145657chr7:86577238ENST00000297222018951_10290790.0Topological domainCytoplasmic
TgeneKIAA1324Lchr7:138145657chr7:86577238ENST0000041631402148_9290863.0Topological domainExtracellular
TgeneKIAA1324Lchr7:138145657chr7:86577238ENST00000416314021951_10290863.0Topological domainCytoplasmic
TgeneKIAA1324Lchr7:138145657chr7:86577238ENST00000450689122951_10291031030.0Topological domainCytoplasmic
TgeneKIAA1324Lchr7:138145657chr7:86577238ENST00000297222018930_9500790.0TransmembraneHelical
TgeneKIAA1324Lchr7:138145657chr7:86577238ENST00000416314021930_9500863.0TransmembraneHelical
TgeneKIAA1324Lchr7:138145657chr7:86577238ENST00000450689122930_9501031030.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRIM24chr7:138145657chr7:86577238ENST00000343526+119289_3591211051.0Coiled coilOntology_term=ECO:0000255
HgeneTRIM24chr7:138145657chr7:86577238ENST00000415680+119289_3591211017.0Coiled coilOntology_term=ECO:0000255
HgeneTRIM24chr7:138145657chr7:86577238ENST00000343526+119344_3471211051.0Compositional biasNote=Poly-Gln
HgeneTRIM24chr7:138145657chr7:86577238ENST00000415680+119344_3471211017.0Compositional biasNote=Poly-Gln
HgeneTRIM24chr7:138145657chr7:86577238ENST00000343526+119932_9871211051.0DomainBromo
HgeneTRIM24chr7:138145657chr7:86577238ENST00000415680+119932_9871211017.0DomainBromo
HgeneTRIM24chr7:138145657chr7:86577238ENST00000343526+119891_9071211051.0MotifNuclear localization signal
HgeneTRIM24chr7:138145657chr7:86577238ENST00000415680+119891_9071211017.0MotifNuclear localization signal
HgeneTRIM24chr7:138145657chr7:86577238ENST00000343526+119754_7791211051.0RegionNote=Nuclear receptor binding site (NRBS)
HgeneTRIM24chr7:138145657chr7:86577238ENST00000415680+119754_7791211017.0RegionNote=Nuclear receptor binding site (NRBS)
HgeneTRIM24chr7:138145657chr7:86577238ENST00000343526+119158_2111211051.0Zinc fingerB box-type 1
HgeneTRIM24chr7:138145657chr7:86577238ENST00000343526+119218_2591211051.0Zinc fingerB box-type 2
HgeneTRIM24chr7:138145657chr7:86577238ENST00000343526+119826_8731211051.0Zinc fingerPHD-type
HgeneTRIM24chr7:138145657chr7:86577238ENST00000415680+119158_2111211017.0Zinc fingerB box-type 1
HgeneTRIM24chr7:138145657chr7:86577238ENST00000415680+119218_2591211017.0Zinc fingerB box-type 2
HgeneTRIM24chr7:138145657chr7:86577238ENST00000415680+119826_8731211017.0Zinc fingerPHD-type
TgeneKIAA1324Lchr7:138145657chr7:86577238ENST0000045068912248_9291031030.0Topological domainExtracellular


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Fusion Gene Sequence for TRIM24-KIAA1324L


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>94006_94006_1_TRIM24-KIAA1324L_TRIM24_chr7_138145657_ENST00000343526_KIAA1324L_chr7_86577238_ENST00000450689_length(transcript)=6924nt_BP=579nt
GACAGATACCCTCCTTCCGGCCGCGCCACTCGGGAGGCGGATCCCGTGGGCCTGAGGAGGCTTCCCCCGCCCGGTTTGCTTTCCCTCCCT
CGCTGGCGCTGCCGCGAGTCCACCGAGCGGCCTCTGAGGAGCAGCCGCAGGAGGAGGAGGAGGTCGTCGGGGGCGGCGGGCGGAGACCGC
GCTCTCGCTTCCCCGGCGGCGGCAAGGGCAGGACAATGGAGGTGGCGGTGGAGAAGGCGGTGGCGGCGGCGGCAGCGGCCTCGGCTGCGG
CCTCCGGGGGGCCCTCGGCGGCGCCGAGCGGGGAGAACGAGGCCGAGAGTCGGCAGGGCCCGGACTCGGAGCGCGGCGGCGAGGCGGCCC
GGCTCAACCTGTTGGACACTTGCGCCGTGTGCCACCAGAACATCCAGAGCCGGGCGCCCAAGCTGCTGCCCTGCCTGCACTCTTTCTGCC
AGCGCTGCCTGCCCGCGCCCCAGCGCTACCTCATGCTGCCCGCGCCCATGCTGGGCTCGGCCGAGACCCCGCCACCCGTCCCTGCCCCCG
GCTCGCCGGTCAGCGGCTCGTCGCCGTTCGCCACCCAAGCTTTCTCCTGTGCTTCTGGAGAGTATCTAGAAATGAAGAACCAGGTATGCA
GTAAGTGTGGTGAAGGCACCTATTCCTTGGGCAGTGGCATCAAATTTGATGAATGGGATGAATTGCCGGCAGGATTTTCTAACATCGCAA
CATTCATGGACACTGTGGTGGGCCCTTCTGACAGCAGGCCAGACGGCTGTAACAACTCTTCTTGGATCCCTCGTGGAAACTACATAGAAT
CTAATCGTGATGACTGCACGGTGTCTTTGATCTATGCTGTGCACCTTAAGAAGTCAGGCTATGTCTTCTTTGAGTACCAGTATGTCGACA
ACAACATCTTCTTTGAGTTCTTTATTCAAAATGATCAGTGCCAGGAGATGGACACCACCACTGACAAGTGGGTAAAACTTACAGACAATG
GAGAATGGGGCTCTCATTCTGTAATGCTGAAATCAGGCACAAACATACTCTACTGGAGAACTACAGGCATCCTTATGGGTTCTAAGGCGG
TCAAGCCTGTGCTGGTAAAAAATATCACAATTGAAGGGGTGGCGTACACATCAGAATGTTTTCCTTGCAAGCCAGGCACATTCAGCAACA
AACCAGGTTCATTCAACTGCCAGGTGTGTCCCAGAAACACCTATTCTGAGAAAGGAGCCAAAGAATGTATAAGGTGTAAAGACGACTCTC
AATTTTCAGAGGAAGGATCCAGTGAGTGTACAGAGCGCCCTCCCTGTACCACAAAAGACTATTTCCAGATCCATACTCCATGTGATGAAG
AAGGAAAGACACAGATAATGTACAAGTGGATAGAGCCCAAAATCTGCCGGGAGGATCTCACAGATGCTATTAGATTGCCCCCTTCTGGAG
AGAAGAAGGATTGTCCGCCTTGCAACCCTGGATTTTATAACAATGGATCATCTTCTTGCCATCCCTGTCCTCCTGGAACATTTTCAGATG
GAACCAAAGAATGTAGACCATGTCCAGCAGGAACGGAGCCTGCACTTGGCTTTGAATATAAATGGTGGAATGTCCTTCCTGGCAACATGA
AAACTTCCTGCTTCAATGTTGGGAATTCAAAGTGCGATGGAATGAATGGTTGGGAGGTGGCTGGAGATCATATCCAGAGTGGGGCTGGAG
GTTCTGACAATGATTACCTGATCTTAAACTTGCATATCCCAGGATTTAAACCACCAACATCTATGACTGGAGCCACGGGTTCTGAACTAG
GAAGAATAACATTTGTCTTTGAGACCCTCTGTTCAGCTGACTGTGTTTTGTACTTCATGGTGGATATTAATAGAAAAAGTACAAATGTGG
TAGAATCGTGGGGTGGAACCAAAGAAAAACAAGCTTACACCCATATCATCTTCAAGAATGCAACTTTTACATTTACATGGGCATTCCAGA
GAACTAATCAGGGTCAAGATAATAGACGGTTCATCAATGACATGGTGAAGATTTATTCTATCACAGCCACTAATGCAGTTGATGGGGTGG
CGTCCTCATGCCGTGCCTGTGCCCTCGGTTCTGAACAGTCGGGTTCATCGTGTGTCCCCTGCCCTCCAGGCCACTACATTGAGAAAGAAA
CCAACCAGTGCAAGGAATGTCCACCTGACACCTACCTGTCCATACATCAGGTCTATGGCAAAGAGGCTTGTATTCCATGCGGGCCTGGGA
GTAAAAACAATCAGGACCATTCGGTTTGCTATAGTGACTGCTTTTTCTACCATGAAAAAGAAAATCAGAGTTTGCACTATGACTTTAGCA
ACCTCAGCAGTGTGGGCTCATTAATGAATGGCCCCAGCTTCACCTCCAAAGGAACAAAATACTTCCATTTCTTCAATATCAGTTTATGTG
GGCATGAGGGGAAGAAGATGGCTCTCTGTACCAACAATATAACAGACTTTACAGTAAAAGAAATAGTGGCAGGGTCAGATGATTACACAA
ATTTGGTAGGGGCATTTGTATGCCAGTCAACAATTATTCCTTCTGAAAGTAAGGGTTTCCGAGCAGCCTTATCATCACAATCCATCATTC
TGGCAGATACATTCATAGGAGTCACAGTTGAAACCACATTGAAAAATATTAATATAAAAGAAGATATGTTCCCAGTTCCAACAAGCCAAA
TACCAGATGTGCATTTCTTTTATAAGTCTTCTACAGCAACAACATCTTGTATTAATGGCCGATCAACTGCTGTGAAAATGAGGTGTAATC
CTACTAAATCTGGAGCAGGAGTGATTTCAGTCCCCAGCAAGTGCCCAGCAGGTACCTGTGATGGGTGTACGTTCTATTTCCTGTGGGAGA
GTGCTGAAGCTTGCCCTCTGTGTACGGAGCATGACTTCCATGAGATTGAGGGAGCCTGCAAGAGAGGATTTCAGGAAACCTTGTATGTGT
GGAATGAACCTAAATGGTGCATTAAAGGAATTTCTTTGCCTGAGAAAAAGTTGGCAACCTGTGAAACGGTTGACTTTTGGCTGAAGGTGG
GAGCCGGTGTGGGAGCTTTTACTGCCGTTTTGCTGGTGGCTCTGACCTGCTACTTCTGGAAAAAGAATCAAAAACTGGAATACAAATATT
CCAAGTTAGTAATGACGACTAACTCAAAAGAGTGTGAACTCCCGGCTGCAGACAGTTGTGCTATCATGGAAGGAGAAGATAATGAAGAGG
AAGTTGTATATTCCAATAAACAGTCACTACTAGGAAAACTCAAATCTTTGGCAACCAAGGAAAAAGAAGACCATTTTGAATCTGTTCAAC
TGAAAACCTCAAGATCCCCAAATATATGAAGAGACAGTGCTGTAGCCTTGAGACTAATGAACAAAGAAACCTGCTCTAGTTTTACAGGAC
CATATTTTAGGGTCTGTCCTCATACCTGTCACATTGGTGATCTCACAGAGGAGGGCCATGCCGCTGAAAAGGGAAGGAGATTGAAACATT
TGATTGCCTTATCACATGGTCAAGTACCTTGCCAAATAAAGGAAAGCAAATGATTTGGGTCTCAACTGAAGATGAAGCTCAACTCAGGAA
GAGATTTATCTGTATATACACATAACTGAAAACCAAGTTTAAGCCCACCAATGCACTGCTGATGCATGCCATATAATTAATGGGTAACTT
TTATTCTTTATGATGTCTACATAACAAGTGTGATTTGGAAGGCACATGTGAGCATATGCATTATGATCCAATTTATGTTTTTTCTTTGTT
TATATTTTGGGGAAAATTAAAATTTTTTTAAGGTATATTTTTCCCATTATTTATTTTCCTGACCTTAAAACAGCTTTTCTACTAAAAAAT
GGTGAGCAATGAAGACAATAAATTTTTCATTTTTCCATAGGTTATCTTCTCTTGATTTAAATTTCAGGAAGAGTTAGCATGTGCTTGGGT
TATCTAGATTTATAATTGCCTTTGAAATTCCATCCTCGTTGGAGCTGGTAAGAAGGGCTTGACTGAAAGTTTGAAGGAATCTAAAAAACA
AAAAAGTAAGAAAGGTAACGAGAAGCCCTAATTCTCCATTAATGCAAACTAGCTGCTAGTATCATAGAAGTCAAATGACTTAAAACAGTT
TATGTAGTGCTAGAAGTATAATTAAAGTAAATAGGAAAGCTTGTCAATCAAATCACTGGCAAAATCATGAAGAAGAGAGTGAGAAGGTTT
GTCTATAAGTACAGATGACTGTATGAAATACTGGGGTAATTTCATGGTCTCCAGAAAATGTCAGTGGGACTTTTGTTCTTTGTCAAGCAC
CAGAGGTTATATGGTTATTTTTCTGCTGCAAGACTTTGAGGATGTTGACTTTCTCAGAAACTTTTTAAAAAAATAATCCAATAAGGCAGG
AATTCAGTTTTGAAAAATTACATATAATTGTATTCATAATAAGAATGTGGTTATTTCATAAGCAGTTATGAAAGAATTATTGTTCTTATT
CAAAAGTGATCCAGATAATTGTGATATTTTCTATGGTGGGCTACTGGTATTAGCACGACTTGGATATTATTTGTTGAAGGAAGTATGAAT
GAAGTTGGATTTGACCAATTTCGTGTAAACCTTAATTGATTTAAAACTGGGAAAGAGGGGGGTTTCCTGGCCATTGCTGATCTAAGGTGC
TCTTATTTGTTTCCAATAAACAGTAATCTTTATAGACCTTAATGCAGATTTAAAAAAATAGTTGTGATTGGCTGAGAGAGGCAGGGCATA
TATGTAGGGAAATGATTTGCCCCAAGCATTCCAATGAAGTATGACTTGTAACTTTTGTGTCTGAAGGTGGTGTCTTTATTTTTGTGGAAA
ATGGGAGAAAAATGAATAATTGTGTTTATTTGGCTGATTGGTAATACACTAGACCATTCTGTTATTATTGAATGAATGTTTTGTGTATAT
CTCTGCTGTTGCACATATGAGTATAGGTGAGGTTGTCATTGTTTGCTCTGGGATTCAGGGAGGGAGTCACTTTGCATAAACCTTTTTTTG
CATTTAATTTCTTGAATGTTCTTATAAAGAAGACATTATGTTGGCATTCTTCATTTTTATCCTGCCAACAGAGTGCTTATGAGCATGTCT
GCATTTTGATCAAAATTTAAACAGAAGAGTGAAAATACATTTGAAATGAACCCTTTCAGAGGAACCCTGGCAAAGCTGTATAGACTGGAC
AGAGTGAGAAAACTTCCACAGCCACCTGTCACCTTTCTCCTCATCTTCCACTGTGTTCAATATGTATGTTCCAAGCCATAGAGATAATTG
GGATTTTCTCCCAGGTAGCTTCTTTCTTCTCCTGTCACTGGACTAAAATCTCTGACATGTCAAAAATGCCTTAAATTTTAATGAACTCTC
CGAAAATGTAGTTGATATTGGAGAATTTATTTTATTTCTAATTTTAGATATTAAATATATTTTGTCAGCACAGTCCCATCTTTGGGAAGG
AGGTGATTTTTTCCCTTGGATTCCAGTGGTTTGTCATTTTATTTCAAGCACTGAAGAAGTATGACAGAAAGAATATTATGGGGAAAATAT
TTAGACCAATCCTGGCTATAAAATTTCCTTTAGTTTTATGCCTGGCCTTTGCAAAGCTCAGTGAAATGTTGAAAGGAATAAATTAATCAT
GTTTCTGTGACTTTTGATTGACACTTGTTCCTTTTCCCCCCTAAGTGGTAGAAGAAGTTATTTGTTATTTTTCTAAAAGGCACAATTTTG
AAGCCTTAACTACTTCATTAAGTCAACTGTTGCCTATAACATCTCTTAGCACTCGTCAAAACGTATTTAAATCAATTTTCCAATGGATGA
GAACATGTCTTCTGTGGATAAATTATATTATGTCATTTAACAACATTGAGCATTTTGATATGTGTTCACTGAATTAAAAAACCTGAATTT
CATTATTGTTGACTTTTCCCCTCTTTAGTTACTAGTAATCACATCCTTTCTAGGATTAAAAATATTTCATAGTATTTTTGTGTAGATGTC
TGTCCTTATTTTCTTCCCAAAGAAAAAAGGTTGTTTAAATTGATTATGTGGAAGAATTACTTGGGTCCAGTCTTTAGCATCTGGGGTCTC
CAGGTCCCCAGGTGGGTCATGATTGACTGCTTCTTCAAGACCCATCTTGCCAACTCTCACTTGATGTCTGTCAATAGAACTACTTCCTGT
GGCACATGGTTATTTCTAATGGGAGGCTAATGTGTACATAATTTCTCTCTTCCTCATAGAAATAAATTTCTCTGGGGGTTGCTGTGAGAG
GATGACTTCATTAGCCATGTTTAAAGTGAGTGTACTGCTCACGTTTATCTTTGTACACTAAGAGTATGTAGAGTTGATCTTCAGAGAAAC
TAAACCTCCCTCATATCTATTTATAGTAATCATGAATATGATTGCAGTTGACAGGCCCAACTCCTAAACTGAGTTTGCCCAAAGAAAATG
TCCTTAGAGGAGTAAACTTTTAGAAATCTCAACACCCGACTCATTCGTTGGAAGCTAAAATGGAATTCATCTTCATACTAACTGGCTACA
GATTATTCTCTTGCTGGATTTTACTTTTATTTTAACATTTTTACATGAGTTCCTTTTAGAATCATAAATGAAAGAAGTAAAACTTTAAGA
TGGGAATGAATAATTGAAAAGAGAATTATATTTACTATTATAATTGATATTATTCGCTATTATGATTACACTTGTCTAGATCAGAGCCCA
GCAAACATTTTTTTTGTAAAGGGTCAGATAGTACATAGTTTTGGCTTTGCAGGGCATGTGGGCTCTATTGCATTTACTCAACTCTGCCAT

>94006_94006_1_TRIM24-KIAA1324L_TRIM24_chr7_138145657_ENST00000343526_KIAA1324L_chr7_86577238_ENST00000450689_length(amino acids)=1088AA_BP=162
MALPRVHRAASEEQPQEEEEVVGGGGRRPRSRFPGGGKGRTMEVAVEKAVAAAAAASAAASGGPSAAPSGENEAESRQGPDSERGGEAAR
LNLLDTCAVCHQNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFATQAFSCASGEYLEMKNQVCS
KCGEGTYSLGSGIKFDEWDELPAGFSNIATFMDTVVGPSDSRPDGCNNSSWIPRGNYIESNRDDCTVSLIYAVHLKKSGYVFFEYQYVDN
NIFFEFFIQNDQCQEMDTTTDKWVKLTDNGEWGSHSVMLKSGTNILYWRTTGILMGSKAVKPVLVKNITIEGVAYTSECFPCKPGTFSNK
PGSFNCQVCPRNTYSEKGAKECIRCKDDSQFSEEGSSECTERPPCTTKDYFQIHTPCDEEGKTQIMYKWIEPKICREDLTDAIRLPPSGE
KKDCPPCNPGFYNNGSSSCHPCPPGTFSDGTKECRPCPAGTEPALGFEYKWWNVLPGNMKTSCFNVGNSKCDGMNGWEVAGDHIQSGAGG
SDNDYLILNLHIPGFKPPTSMTGATGSELGRITFVFETLCSADCVLYFMVDINRKSTNVVESWGGTKEKQAYTHIIFKNATFTFTWAFQR
TNQGQDNRRFINDMVKIYSITATNAVDGVASSCRACALGSEQSGSSCVPCPPGHYIEKETNQCKECPPDTYLSIHQVYGKEACIPCGPGS
KNNQDHSVCYSDCFFYHEKENQSLHYDFSNLSSVGSLMNGPSFTSKGTKYFHFFNISLCGHEGKKMALCTNNITDFTVKEIVAGSDDYTN
LVGAFVCQSTIIPSESKGFRAALSSQSIILADTFIGVTVETTLKNINIKEDMFPVPTSQIPDVHFFYKSSTATTSCINGRSTAVKMRCNP
TKSGAGVISVPSKCPAGTCDGCTFYFLWESAEACPLCTEHDFHEIEGACKRGFQETLYVWNEPKWCIKGISLPEKKLATCETVDFWLKVG
AGVGAFTAVLLVALTCYFWKKNQKLEYKYSKLVMTTNSKECELPAADSCAIMEGEDNEEEVVYSNKQSLLGKLKSLATKEKEDHFESVQL

--------------------------------------------------------------
>94006_94006_2_TRIM24-KIAA1324L_TRIM24_chr7_138145657_ENST00000415680_KIAA1324L_chr7_86577238_ENST00000450689_length(transcript)=6823nt_BP=478nt
CCGCGAGTCCACCGAGCGGCCTCTGAGGAGCAGCCGCAGGAGGAGGAGGAGGTCGTCGGGGGCGGCGGGCGGAGACCGCGCTCTCGCTTC
CCCGGCGGCGGCAAGGGCAGGACAATGGAGGTGGCGGTGGAGAAGGCGGTGGCGGCGGCGGCAGCGGCCTCGGCTGCGGCCTCCGGGGGG
CCCTCGGCGGCGCCGAGCGGGGAGAACGAGGCCGAGAGTCGGCAGGGCCCGGACTCGGAGCGCGGCGGCGAGGCGGCCCGGCTCAACCTG
TTGGACACTTGCGCCGTGTGCCACCAGAACATCCAGAGCCGGGCGCCCAAGCTGCTGCCCTGCCTGCACTCTTTCTGCCAGCGCTGCCTG
CCCGCGCCCCAGCGCTACCTCATGCTGCCCGCGCCCATGCTGGGCTCGGCCGAGACCCCGCCACCCGTCCCTGCCCCCGGCTCGCCGGTC
AGCGGCTCGTCGCCGTTCGCCACCCAAGCTTTCTCCTGTGCTTCTGGAGAGTATCTAGAAATGAAGAACCAGGTATGCAGTAAGTGTGGT
GAAGGCACCTATTCCTTGGGCAGTGGCATCAAATTTGATGAATGGGATGAATTGCCGGCAGGATTTTCTAACATCGCAACATTCATGGAC
ACTGTGGTGGGCCCTTCTGACAGCAGGCCAGACGGCTGTAACAACTCTTCTTGGATCCCTCGTGGAAACTACATAGAATCTAATCGTGAT
GACTGCACGGTGTCTTTGATCTATGCTGTGCACCTTAAGAAGTCAGGCTATGTCTTCTTTGAGTACCAGTATGTCGACAACAACATCTTC
TTTGAGTTCTTTATTCAAAATGATCAGTGCCAGGAGATGGACACCACCACTGACAAGTGGGTAAAACTTACAGACAATGGAGAATGGGGC
TCTCATTCTGTAATGCTGAAATCAGGCACAAACATACTCTACTGGAGAACTACAGGCATCCTTATGGGTTCTAAGGCGGTCAAGCCTGTG
CTGGTAAAAAATATCACAATTGAAGGGGTGGCGTACACATCAGAATGTTTTCCTTGCAAGCCAGGCACATTCAGCAACAAACCAGGTTCA
TTCAACTGCCAGGTGTGTCCCAGAAACACCTATTCTGAGAAAGGAGCCAAAGAATGTATAAGGTGTAAAGACGACTCTCAATTTTCAGAG
GAAGGATCCAGTGAGTGTACAGAGCGCCCTCCCTGTACCACAAAAGACTATTTCCAGATCCATACTCCATGTGATGAAGAAGGAAAGACA
CAGATAATGTACAAGTGGATAGAGCCCAAAATCTGCCGGGAGGATCTCACAGATGCTATTAGATTGCCCCCTTCTGGAGAGAAGAAGGAT
TGTCCGCCTTGCAACCCTGGATTTTATAACAATGGATCATCTTCTTGCCATCCCTGTCCTCCTGGAACATTTTCAGATGGAACCAAAGAA
TGTAGACCATGTCCAGCAGGAACGGAGCCTGCACTTGGCTTTGAATATAAATGGTGGAATGTCCTTCCTGGCAACATGAAAACTTCCTGC
TTCAATGTTGGGAATTCAAAGTGCGATGGAATGAATGGTTGGGAGGTGGCTGGAGATCATATCCAGAGTGGGGCTGGAGGTTCTGACAAT
GATTACCTGATCTTAAACTTGCATATCCCAGGATTTAAACCACCAACATCTATGACTGGAGCCACGGGTTCTGAACTAGGAAGAATAACA
TTTGTCTTTGAGACCCTCTGTTCAGCTGACTGTGTTTTGTACTTCATGGTGGATATTAATAGAAAAAGTACAAATGTGGTAGAATCGTGG
GGTGGAACCAAAGAAAAACAAGCTTACACCCATATCATCTTCAAGAATGCAACTTTTACATTTACATGGGCATTCCAGAGAACTAATCAG
GGTCAAGATAATAGACGGTTCATCAATGACATGGTGAAGATTTATTCTATCACAGCCACTAATGCAGTTGATGGGGTGGCGTCCTCATGC
CGTGCCTGTGCCCTCGGTTCTGAACAGTCGGGTTCATCGTGTGTCCCCTGCCCTCCAGGCCACTACATTGAGAAAGAAACCAACCAGTGC
AAGGAATGTCCACCTGACACCTACCTGTCCATACATCAGGTCTATGGCAAAGAGGCTTGTATTCCATGCGGGCCTGGGAGTAAAAACAAT
CAGGACCATTCGGTTTGCTATAGTGACTGCTTTTTCTACCATGAAAAAGAAAATCAGAGTTTGCACTATGACTTTAGCAACCTCAGCAGT
GTGGGCTCATTAATGAATGGCCCCAGCTTCACCTCCAAAGGAACAAAATACTTCCATTTCTTCAATATCAGTTTATGTGGGCATGAGGGG
AAGAAGATGGCTCTCTGTACCAACAATATAACAGACTTTACAGTAAAAGAAATAGTGGCAGGGTCAGATGATTACACAAATTTGGTAGGG
GCATTTGTATGCCAGTCAACAATTATTCCTTCTGAAAGTAAGGGTTTCCGAGCAGCCTTATCATCACAATCCATCATTCTGGCAGATACA
TTCATAGGAGTCACAGTTGAAACCACATTGAAAAATATTAATATAAAAGAAGATATGTTCCCAGTTCCAACAAGCCAAATACCAGATGTG
CATTTCTTTTATAAGTCTTCTACAGCAACAACATCTTGTATTAATGGCCGATCAACTGCTGTGAAAATGAGGTGTAATCCTACTAAATCT
GGAGCAGGAGTGATTTCAGTCCCCAGCAAGTGCCCAGCAGGTACCTGTGATGGGTGTACGTTCTATTTCCTGTGGGAGAGTGCTGAAGCT
TGCCCTCTGTGTACGGAGCATGACTTCCATGAGATTGAGGGAGCCTGCAAGAGAGGATTTCAGGAAACCTTGTATGTGTGGAATGAACCT
AAATGGTGCATTAAAGGAATTTCTTTGCCTGAGAAAAAGTTGGCAACCTGTGAAACGGTTGACTTTTGGCTGAAGGTGGGAGCCGGTGTG
GGAGCTTTTACTGCCGTTTTGCTGGTGGCTCTGACCTGCTACTTCTGGAAAAAGAATCAAAAACTGGAATACAAATATTCCAAGTTAGTA
ATGACGACTAACTCAAAAGAGTGTGAACTCCCGGCTGCAGACAGTTGTGCTATCATGGAAGGAGAAGATAATGAAGAGGAAGTTGTATAT
TCCAATAAACAGTCACTACTAGGAAAACTCAAATCTTTGGCAACCAAGGAAAAAGAAGACCATTTTGAATCTGTTCAACTGAAAACCTCA
AGATCCCCAAATATATGAAGAGACAGTGCTGTAGCCTTGAGACTAATGAACAAAGAAACCTGCTCTAGTTTTACAGGACCATATTTTAGG
GTCTGTCCTCATACCTGTCACATTGGTGATCTCACAGAGGAGGGCCATGCCGCTGAAAAGGGAAGGAGATTGAAACATTTGATTGCCTTA
TCACATGGTCAAGTACCTTGCCAAATAAAGGAAAGCAAATGATTTGGGTCTCAACTGAAGATGAAGCTCAACTCAGGAAGAGATTTATCT
GTATATACACATAACTGAAAACCAAGTTTAAGCCCACCAATGCACTGCTGATGCATGCCATATAATTAATGGGTAACTTTTATTCTTTAT
GATGTCTACATAACAAGTGTGATTTGGAAGGCACATGTGAGCATATGCATTATGATCCAATTTATGTTTTTTCTTTGTTTATATTTTGGG
GAAAATTAAAATTTTTTTAAGGTATATTTTTCCCATTATTTATTTTCCTGACCTTAAAACAGCTTTTCTACTAAAAAATGGTGAGCAATG
AAGACAATAAATTTTTCATTTTTCCATAGGTTATCTTCTCTTGATTTAAATTTCAGGAAGAGTTAGCATGTGCTTGGGTTATCTAGATTT
ATAATTGCCTTTGAAATTCCATCCTCGTTGGAGCTGGTAAGAAGGGCTTGACTGAAAGTTTGAAGGAATCTAAAAAACAAAAAAGTAAGA
AAGGTAACGAGAAGCCCTAATTCTCCATTAATGCAAACTAGCTGCTAGTATCATAGAAGTCAAATGACTTAAAACAGTTTATGTAGTGCT
AGAAGTATAATTAAAGTAAATAGGAAAGCTTGTCAATCAAATCACTGGCAAAATCATGAAGAAGAGAGTGAGAAGGTTTGTCTATAAGTA
CAGATGACTGTATGAAATACTGGGGTAATTTCATGGTCTCCAGAAAATGTCAGTGGGACTTTTGTTCTTTGTCAAGCACCAGAGGTTATA
TGGTTATTTTTCTGCTGCAAGACTTTGAGGATGTTGACTTTCTCAGAAACTTTTTAAAAAAATAATCCAATAAGGCAGGAATTCAGTTTT
GAAAAATTACATATAATTGTATTCATAATAAGAATGTGGTTATTTCATAAGCAGTTATGAAAGAATTATTGTTCTTATTCAAAAGTGATC
CAGATAATTGTGATATTTTCTATGGTGGGCTACTGGTATTAGCACGACTTGGATATTATTTGTTGAAGGAAGTATGAATGAAGTTGGATT
TGACCAATTTCGTGTAAACCTTAATTGATTTAAAACTGGGAAAGAGGGGGGTTTCCTGGCCATTGCTGATCTAAGGTGCTCTTATTTGTT
TCCAATAAACAGTAATCTTTATAGACCTTAATGCAGATTTAAAAAAATAGTTGTGATTGGCTGAGAGAGGCAGGGCATATATGTAGGGAA
ATGATTTGCCCCAAGCATTCCAATGAAGTATGACTTGTAACTTTTGTGTCTGAAGGTGGTGTCTTTATTTTTGTGGAAAATGGGAGAAAA
ATGAATAATTGTGTTTATTTGGCTGATTGGTAATACACTAGACCATTCTGTTATTATTGAATGAATGTTTTGTGTATATCTCTGCTGTTG
CACATATGAGTATAGGTGAGGTTGTCATTGTTTGCTCTGGGATTCAGGGAGGGAGTCACTTTGCATAAACCTTTTTTTGCATTTAATTTC
TTGAATGTTCTTATAAAGAAGACATTATGTTGGCATTCTTCATTTTTATCCTGCCAACAGAGTGCTTATGAGCATGTCTGCATTTTGATC
AAAATTTAAACAGAAGAGTGAAAATACATTTGAAATGAACCCTTTCAGAGGAACCCTGGCAAAGCTGTATAGACTGGACAGAGTGAGAAA
ACTTCCACAGCCACCTGTCACCTTTCTCCTCATCTTCCACTGTGTTCAATATGTATGTTCCAAGCCATAGAGATAATTGGGATTTTCTCC
CAGGTAGCTTCTTTCTTCTCCTGTCACTGGACTAAAATCTCTGACATGTCAAAAATGCCTTAAATTTTAATGAACTCTCCGAAAATGTAG
TTGATATTGGAGAATTTATTTTATTTCTAATTTTAGATATTAAATATATTTTGTCAGCACAGTCCCATCTTTGGGAAGGAGGTGATTTTT
TCCCTTGGATTCCAGTGGTTTGTCATTTTATTTCAAGCACTGAAGAAGTATGACAGAAAGAATATTATGGGGAAAATATTTAGACCAATC
CTGGCTATAAAATTTCCTTTAGTTTTATGCCTGGCCTTTGCAAAGCTCAGTGAAATGTTGAAAGGAATAAATTAATCATGTTTCTGTGAC
TTTTGATTGACACTTGTTCCTTTTCCCCCCTAAGTGGTAGAAGAAGTTATTTGTTATTTTTCTAAAAGGCACAATTTTGAAGCCTTAACT
ACTTCATTAAGTCAACTGTTGCCTATAACATCTCTTAGCACTCGTCAAAACGTATTTAAATCAATTTTCCAATGGATGAGAACATGTCTT
CTGTGGATAAATTATATTATGTCATTTAACAACATTGAGCATTTTGATATGTGTTCACTGAATTAAAAAACCTGAATTTCATTATTGTTG
ACTTTTCCCCTCTTTAGTTACTAGTAATCACATCCTTTCTAGGATTAAAAATATTTCATAGTATTTTTGTGTAGATGTCTGTCCTTATTT
TCTTCCCAAAGAAAAAAGGTTGTTTAAATTGATTATGTGGAAGAATTACTTGGGTCCAGTCTTTAGCATCTGGGGTCTCCAGGTCCCCAG
GTGGGTCATGATTGACTGCTTCTTCAAGACCCATCTTGCCAACTCTCACTTGATGTCTGTCAATAGAACTACTTCCTGTGGCACATGGTT
ATTTCTAATGGGAGGCTAATGTGTACATAATTTCTCTCTTCCTCATAGAAATAAATTTCTCTGGGGGTTGCTGTGAGAGGATGACTTCAT
TAGCCATGTTTAAAGTGAGTGTACTGCTCACGTTTATCTTTGTACACTAAGAGTATGTAGAGTTGATCTTCAGAGAAACTAAACCTCCCT
CATATCTATTTATAGTAATCATGAATATGATTGCAGTTGACAGGCCCAACTCCTAAACTGAGTTTGCCCAAAGAAAATGTCCTTAGAGGA
GTAAACTTTTAGAAATCTCAACACCCGACTCATTCGTTGGAAGCTAAAATGGAATTCATCTTCATACTAACTGGCTACAGATTATTCTCT
TGCTGGATTTTACTTTTATTTTAACATTTTTACATGAGTTCCTTTTAGAATCATAAATGAAAGAAGTAAAACTTTAAGATGGGAATGAAT
AATTGAAAAGAGAATTATATTTACTATTATAATTGATATTATTCGCTATTATGATTACACTTGTCTAGATCAGAGCCCAGCAAACATTTT
TTTTGTAAAGGGTCAGATAGTACATAGTTTTGGCTTTGCAGGGCATGTGGGCTCTATTGCATTTACTCAACTCTGCCATTGTAGTATGAA

>94006_94006_2_TRIM24-KIAA1324L_TRIM24_chr7_138145657_ENST00000415680_KIAA1324L_chr7_86577238_ENST00000450689_length(amino acids)=1047AA_BP=121
MEVAVEKAVAAAAAASAAASGGPSAAPSGENEAESRQGPDSERGGEAARLNLLDTCAVCHQNIQSRAPKLLPCLHSFCQRCLPAPQRYLM
LPAPMLGSAETPPPVPAPGSPVSGSSPFATQAFSCASGEYLEMKNQVCSKCGEGTYSLGSGIKFDEWDELPAGFSNIATFMDTVVGPSDS
RPDGCNNSSWIPRGNYIESNRDDCTVSLIYAVHLKKSGYVFFEYQYVDNNIFFEFFIQNDQCQEMDTTTDKWVKLTDNGEWGSHSVMLKS
GTNILYWRTTGILMGSKAVKPVLVKNITIEGVAYTSECFPCKPGTFSNKPGSFNCQVCPRNTYSEKGAKECIRCKDDSQFSEEGSSECTE
RPPCTTKDYFQIHTPCDEEGKTQIMYKWIEPKICREDLTDAIRLPPSGEKKDCPPCNPGFYNNGSSSCHPCPPGTFSDGTKECRPCPAGT
EPALGFEYKWWNVLPGNMKTSCFNVGNSKCDGMNGWEVAGDHIQSGAGGSDNDYLILNLHIPGFKPPTSMTGATGSELGRITFVFETLCS
ADCVLYFMVDINRKSTNVVESWGGTKEKQAYTHIIFKNATFTFTWAFQRTNQGQDNRRFINDMVKIYSITATNAVDGVASSCRACALGSE
QSGSSCVPCPPGHYIEKETNQCKECPPDTYLSIHQVYGKEACIPCGPGSKNNQDHSVCYSDCFFYHEKENQSLHYDFSNLSSVGSLMNGP
SFTSKGTKYFHFFNISLCGHEGKKMALCTNNITDFTVKEIVAGSDDYTNLVGAFVCQSTIIPSESKGFRAALSSQSIILADTFIGVTVET
TLKNINIKEDMFPVPTSQIPDVHFFYKSSTATTSCINGRSTAVKMRCNPTKSGAGVISVPSKCPAGTCDGCTFYFLWESAEACPLCTEHD
FHEIEGACKRGFQETLYVWNEPKWCIKGISLPEKKLATCETVDFWLKVGAGVGAFTAVLLVALTCYFWKKNQKLEYKYSKLVMTTNSKEC

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TRIM24-KIAA1324L


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneTRIM24chr7:138145657chr7:86577238ENST00000343526+119834_840121.333333333333331051.0histone H3 that is not methylated at 'Lys-4' (H3K4me0)
HgeneTRIM24chr7:138145657chr7:86577238ENST00000415680+119834_840121.333333333333331017.0histone H3 that is not methylated at 'Lys-4' (H3K4me0)


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TRIM24-KIAA1324L


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TRIM24-KIAA1324L


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource