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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:TRIM35-GSR (FusionGDB2 ID:94090)

Fusion Gene Summary for TRIM35-GSR

Fusion gene summary

Fusion gene information	Fusion gene name: TRIM35-GSR
	Fusion gene ID: 94090
		Hgene	Tgene
	Gene symbol	TRIM35	GSR
	Gene ID	23087	2936
	Gene name	tripartite motif containing 35	glutathione-disulfide reductase
	Synonyms	HLS5\|MAIR	GR\|GSRD\|HEL-75\|HEL-S-122m
	Cytomap	8p21.2	8p12
	Type of gene	protein-coding	protein-coding
	Description	tripartite motif-containing protein 35hemopoietic lineage switch protein 5	glutathione reductase, mitochondrialGRaseepididymis luminal protein 75epididymis secretory sperm binding protein Li 122mglutathione S-reductase
	Modification date	20200313	20200313
	UniProtAcc	.	P00390
	Ensembl transtripts involved in fusion gene	ENST00000305364, ENST00000521253,	ENST00000221130, ENST00000414019, ENST00000537535, ENST00000541648, ENST00000546342,
Fusion gene scores	* DoF score	6 X 5 X 5=150	6 X 5 X 4=120
	# samples	7	6
	** MAII score	log2(7/150*10)=-1.09953567355091 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(6/120*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: TRIM35 [Title/Abstract] AND GSR [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	TRIM35(27151597)-GSR(30569605), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	TRIM35	GO:0043065	positive regulation of apoptotic process	14662771
Hgene	TRIM35	GO:0045087	innate immune response	18248090
Hgene	TRIM35	GO:0045930	negative regulation of mitotic cell cycle	14662771
Hgene	TRIM35	GO:1902187	negative regulation of viral release from host cell	18248090

Fusion gene breakpoints across TRIM35 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across GSR (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-BH-A0DG-01A	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-

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Fusion Gene ORF analysis for TRIM35-GSR

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000305364	ENST00000221130	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-
In-frame	ENST00000305364	ENST00000414019	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-
In-frame	ENST00000305364	ENST00000537535	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-
In-frame	ENST00000305364	ENST00000541648	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-
In-frame	ENST00000305364	ENST00000546342	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-
In-frame	ENST00000521253	ENST00000221130	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-
In-frame	ENST00000521253	ENST00000414019	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-
In-frame	ENST00000521253	ENST00000537535	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-
In-frame	ENST00000521253	ENST00000541648	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-
In-frame	ENST00000521253	ENST00000546342	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000305364	TRIM35	chr8	27151597	-	ENST00000221130	GSR	chr8	30569605	-	3563	846	84	2108	674
ENST00000305364	TRIM35	chr8	27151597	-	ENST00000414019	GSR	chr8	30569605	-	3562	846	84	2108	674
ENST00000305364	TRIM35	chr8	27151597	-	ENST00000546342	GSR	chr8	30569605	-	2022	846	84	2021	645
ENST00000305364	TRIM35	chr8	27151597	-	ENST00000537535	GSR	chr8	30569605	-	1863	846	84	1862	592
ENST00000305364	TRIM35	chr8	27151597	-	ENST00000541648	GSR	chr8	30569605	-	1950	846	84	1949	621
ENST00000521253	TRIM35	chr8	27151597	-	ENST00000221130	GSR	chr8	30569605	-	3386	669	3	1931	642
ENST00000521253	TRIM35	chr8	27151597	-	ENST00000414019	GSR	chr8	30569605	-	3385	669	3	1931	642
ENST00000521253	TRIM35	chr8	27151597	-	ENST00000546342	GSR	chr8	30569605	-	1845	669	3	1844	613
ENST00000521253	TRIM35	chr8	27151597	-	ENST00000537535	GSR	chr8	30569605	-	1686	669	3	1685	560
ENST00000521253	TRIM35	chr8	27151597	-	ENST00000541648	GSR	chr8	30569605	-	1773	669	3	1772	589

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000305364	ENST00000221130	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-	0.001544231	0.99845576
ENST00000305364	ENST00000414019	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-	0.001559791	0.9984402
ENST00000305364	ENST00000546342	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-	0.004453954	0.995546
ENST00000305364	ENST00000537535	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-	0.005300671	0.99469936
ENST00000305364	ENST00000541648	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-	0.005627028	0.99437296
ENST00000521253	ENST00000221130	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-	0.001118967	0.99888104
ENST00000521253	ENST00000414019	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-	0.001131856	0.9988682
ENST00000521253	ENST00000546342	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-	0.003648777	0.99635124
ENST00000521253	ENST00000537535	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-	0.004632345	0.99536765
ENST00000521253	ENST00000541648	TRIM35	chr8	27151597	-	GSR	chr8	30569605	-	0.004501614	0.9954984

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Fusion Genomic Features for TRIM35-GSR

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TRIM35-GSR

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:27151597/chr8:30569605)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	GSR P00390
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Maintains high levels of reduced glutathione in the cytosol.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

TRIM35

chr8:27151597

chr8:30569605

ENST00000305364

210_251

254

494.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

TRIM35

chr8:27151597

chr8:30569605

ENST00000305364

21_61

254

494.0

Zinc finger

RING-type

Hgene

TRIM35

chr8:27151597

chr8:30569605

ENST00000305364

96_137

254

494.0

Zinc finger

B box-type

Tgene

GSR

chr8:27151597

chr8:30569605

ENST00000414019

94_102

480.0

Nucleotide binding

Note=FAD

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

TRIM35

chr8:27151597

chr8:30569605

ENST00000305364

284_487

254

494.0

Domain

B30.2/SPRY

Tgene

GSR

chr8:27151597

chr8:30569605

ENST00000221130

94_102

102

523.0

Nucleotide binding

Note=FAD

Tgene

GSR

chr8:27151597

chr8:30569605

ENST00000537535

94_102

102

441.0

Nucleotide binding

Note=FAD

Tgene

GSR

chr8:27151597

chr8:30569605

ENST00000541648

94_102

102

470.0

Nucleotide binding

Note=FAD

Tgene

GSR

chr8:27151597

chr8:30569605

ENST00000546342

94_102

102

494.0

Nucleotide binding

Note=FAD

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Fusion Gene Sequence for TRIM35-GSR

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>94090_94090_1_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000305364_GSR_chr8_30569605_ENST00000221130_length(transcript)=3563nt_BP=846nt
CACTCGGGTCGCGGGCGTTGGCAGCCGGGCGGGTGGGAGGGGCCGGAGCAAAAGTTCCGGGCGCCCGAGCCGGCTGCTCGTGCCATGGAG
CGGAGTCCCGACGTGTCCCCCGGGCCTTCCCGCTCCTTCAAGGAGGAGTTGCTCTGCGCCGTCTGCTACGACCCCTTCCGCGACGCAGTC
ACTCTGCGCTGCGGCCACAACTTCTGCCGCGGGTGCGTGAGCCGCTGCTGGGAGGTGCAGGTGTCGCCCACCTGCCCAGTGTGCAAAGAC
CGCGCGTCACCCGCCGACCTGCGCACCAACCACACCCTCAACAACCTGGTGGAGAAGCTGCTGCGCGAGGAGGCCGAGGGCGCGCGCTGG
ACCAGCTACCGCTTCTCGCGTGTCTGCCGCCTGCACCGCGGACAGCTCAGCCTCTTCTGCCTCGAGGACAAGGAGCTGCTGTGCTGCTCC
TGCCAGGCCGACCCCCGACACCAGGGGCACCGCGTGCAGCCGGTGAAGGACACTGCCCACGACTTTCGGGCCAAGTGCAGGAACATGGAG
CATGCACTGCGGGAGAAGGCCAAGGCCTTCTGGGCCATGCGGCGCTCCTATGAGGCCATCGCCAAGCACAATCAGGTGGAGGCTGCATGG
CTGGAAGGCCGGATCCGGCAGGAGTTTGATAAGCTTCGCGAGTTCTTGAGAGTGGAGGAGCAGGCCATTCTGGATGCCATGGCCGAGGAG
ACAAGGCAGAAGCAACTTCTGGCCGACGAGAAGATGAAGCAGCTCACAGAGGAGACGGAGGTGCTGGCACATGAGATCGAGCGGCTGCAG
ATGGAGATGAAGGAGGACGACGTTTCTTTTCTCATGGTGAATGTTGGATGTGTACCCAAAAAGGTAATGTGGAACACAGCTGTCCACTCT
GAATTCATGCATGATCATGCTGATTATGGCTTTCCAAGTTGTGAGGGTAAATTCAATTGGCGTGTTATTAAGGAAAAGCGGGATGCCTAT
GTGAGCCGCCTGAATGCCATCTATCAAAACAATCTCACCAAGTCCCATATAGAAATCATCCGTGGCCATGCAGCCTTCACGAGTGATCCC
AAGCCCACAATAGAGGTCAGTGGGAAAAAGTACACCGCCCCACACATCCTGATCGCCACAGGTGGTATGCCCTCCACCCCTCATGAGAGC
CAGATCCCCGGTGCCAGCTTAGGAATAACCAGCGATGGATTTTTTCAGCTGGAAGAATTGCCCGGCCGCAGCGTCATTGTTGGTGCAGGT
TACATTGCTGTGGAGATGGCAGGGATCCTGTCAGCCCTGGGTTCTAAGACATCACTGATGATACGGCATGATAAGGTACTTAGAAGTTTT
GATTCAATGATCAGCACCAACTGCACGGAGGAGCTGGAGAACGCTGGCGTGGAGGTGCTGAAGTTCTCCCAGGTCAAGGAGGTTAAAAAG
ACTTTGTCGGGCTTGGAAGTCAGCATGGTTACTGCAGTTCCCGGTAGGCTACCAGTCATGACCATGATTCCAGATGTTGACTGCCTGCTC
TGGGCCATTGGGCGGGTCCCGAATACCAAGGACCTGAGTTTAAACAAACTGGGGATTCAAACCGATGACAAGGGTCATATCATCGTAGAC
GAATTCCAGAATACCAACGTCAAAGGCATCTATGCAGTTGGGGATGTATGTGGAAAAGCTCTTCTTACTCCAGTTGCAATAGCTGCTGGC
CGAAAACTTGCCCATCGACTTTTTGAATATAAGGAAGATTCCAAATTAGATTATAACAACATCCCAACTGTGGTCTTCAGCCACCCCCCT
ATTGGGACAGTGGGACTCACGGAAGATGAAGCCATTCATAAATATGGAATAGAAAATGTGAAGACCTATTCAACGAGCTTTACCCCGATG
TATCACGCAGTTACCAAAAGGAAAACAAAATGTGTGATGAAAATGGTCTGTGCTAACAAGGAAGAAAAGGTGGTTGGGATCCATATGCAG
GGACTTGGGTGTGATGAAATGCTGCAGGGTTTTGCTGTTGCAGTGAAGATGGGAGCAACGAAGGCAGACTTTGACAACACAGTCGCCATT
CACCCTACCTCTTCAGAAGAGCTGGTCACACTTCGTTGAGAACCAGGAGACACGTGTGGCGGGCAGTGGGACCCATAGATCTTCTGAAAT
GAAACAAATAATCACATTGACTTACTGTTTGAGTTTTATGTATTTCTTTATTTTAATCAGGATCTTCTGATAGTGGAAATTTTTAGTACA
TAATAGAACTTATTTATGGAGTTAGAAATTTGTAGTGTTATCCAGGATTGATTTTCATTTGATCACATCTCACAGTAATTAATATTTTCA
AGTTTTTTTTTTATTAACAGCTCTGTGCTAGTTTTTTTTTTCTGTTTTAGCCTCATCCCAAATATAAAGCTTTGTGAAGTACAATTAACT
TAATGTACTTGAATGAATAGAACTTGCTACTTTTTTTTTTTTTTTTTTTGAGACAGAGTTTTGCTCTCATTGCCCAGGCTGGAGTGCGGT
GGTGCTATTTCAGCTCACCACAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTTAGCCTCCCGAATAGCTGGAATTACAGGCACG
CACCACCATGCCTGACTAATTTTGTATTTTTAGTAGACATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTCAAACTCCCACCTTCAGGTG
ATCCGCCCACCTCGGCCTCCTGAGGTGCTGAGATTACAGGCGTGAGCCACTGTGCCAGCTTGCTAATTTTCACAGAAGTTGATGGCAATT
CTTCACATGTAAACAGTGCCAGTGCACAGAACCTTTATATATTTTTTGAAGCCAGTACTGTGCTCTGCATATAACAAAGCTGCTTCAAGG
ATGAGACCTTTTTCTAAAAGCATGTAATGTGAGAAGCCGGCCTGCCTTATTTTCTTTTTTCTTTTTTAATGATTAAAAATAGTTTGTGGC
AAGGCACGGTGGCTCAGGCCTGTAATTCTAGCACTTTGGGAGGCCGAGGCAGGAGGATTACTTGAGCCTACAAGTTTGAGGCCAGCATGC
ACAGCATAGCAAGACTGCATCTCTACAGAGAGTAAAAAAAATTACCCGAGTGTGGTGATGTGCATCTGTAATCTCAGCTACTTGGGAGGC
TGAGGTGAGAGGATCACTTGAGCTTGGGTGAGGTGAGGCTGCAGTGAGTCCTGATCATGCTGCTGCACTCAATCTTGGACAACAGAGCAA
GACCCTGTCTCAAAAAAAAAAAAAAAAAATATATATATATATATATATTATTTTTATGAGGTGAAGTGCATCAAACTTGGGAAAGATTTG
AGGAGGCTGGGAACCTCCTGGAAAACCACTCCTTGAAGAAAGATATGAGAGACATTTAGAAGTGATTCCTGCTTTCAGAAGGAGGTGGAT
TCAAATACATCAAAAGTCCCTTCCTCTGCTAAGTGTTTATAGTTCAATGAATAATTTCAATATTTGTATGTGTTCTTGTCATTTTATTTT

>94090_94090_1_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000305364_GSR_chr8_30569605_ENST00000221130_length(amino acids)=674AA_BP=254
MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGA
RWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEA
AWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMVNVGCVPKKVMWNTAV
HSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPH
ESQIPGASLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEV
KKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIA
AGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIH

--------------------------------------------------------------
>94090_94090_2_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000305364_GSR_chr8_30569605_ENST00000414019_length(transcript)=3562nt_BP=846nt
CACTCGGGTCGCGGGCGTTGGCAGCCGGGCGGGTGGGAGGGGCCGGAGCAAAAGTTCCGGGCGCCCGAGCCGGCTGCTCGTGCCATGGAG
CGGAGTCCCGACGTGTCCCCCGGGCCTTCCCGCTCCTTCAAGGAGGAGTTGCTCTGCGCCGTCTGCTACGACCCCTTCCGCGACGCAGTC
ACTCTGCGCTGCGGCCACAACTTCTGCCGCGGGTGCGTGAGCCGCTGCTGGGAGGTGCAGGTGTCGCCCACCTGCCCAGTGTGCAAAGAC
CGCGCGTCACCCGCCGACCTGCGCACCAACCACACCCTCAACAACCTGGTGGAGAAGCTGCTGCGCGAGGAGGCCGAGGGCGCGCGCTGG
ACCAGCTACCGCTTCTCGCGTGTCTGCCGCCTGCACCGCGGACAGCTCAGCCTCTTCTGCCTCGAGGACAAGGAGCTGCTGTGCTGCTCC
TGCCAGGCCGACCCCCGACACCAGGGGCACCGCGTGCAGCCGGTGAAGGACACTGCCCACGACTTTCGGGCCAAGTGCAGGAACATGGAG
CATGCACTGCGGGAGAAGGCCAAGGCCTTCTGGGCCATGCGGCGCTCCTATGAGGCCATCGCCAAGCACAATCAGGTGGAGGCTGCATGG
CTGGAAGGCCGGATCCGGCAGGAGTTTGATAAGCTTCGCGAGTTCTTGAGAGTGGAGGAGCAGGCCATTCTGGATGCCATGGCCGAGGAG
ACAAGGCAGAAGCAACTTCTGGCCGACGAGAAGATGAAGCAGCTCACAGAGGAGACGGAGGTGCTGGCACATGAGATCGAGCGGCTGCAG
ATGGAGATGAAGGAGGACGACGTTTCTTTTCTCATGGTGAATGTTGGATGTGTACCCAAAAAGGTAATGTGGAACACAGCTGTCCACTCT
GAATTCATGCATGATCATGCTGATTATGGCTTTCCAAGTTGTGAGGGTAAATTCAATTGGCGTGTTATTAAGGAAAAGCGGGATGCCTAT
GTGAGCCGCCTGAATGCCATCTATCAAAACAATCTCACCAAGTCCCATATAGAAATCATCCGTGGCCATGCAGCCTTCACGAGTGATCCC
AAGCCCACAATAGAGGTCAGTGGGAAAAAGTACACCGCCCCACACATCCTGATCGCCACAGGTGGTATGCCCTCCACCCCTCATGAGAGC
CAGATCCCCGGTGCCAGCTTAGGAATAACCAGCGATGGATTTTTTCAGCTGGAAGAATTGCCCGGCCGCAGCGTCATTGTTGGTGCAGGT
TACATTGCTGTGGAGATGGCAGGGATCCTGTCAGCCCTGGGTTCTAAGACATCACTGATGATACGGCATGATAAGGTACTTAGAAGTTTT
GATTCAATGATCAGCACCAACTGCACGGAGGAGCTGGAGAACGCTGGCGTGGAGGTGCTGAAGTTCTCCCAGGTCAAGGAGGTTAAAAAG
ACTTTGTCGGGCTTGGAAGTCAGCATGGTTACTGCAGTTCCCGGTAGGCTACCAGTCATGACCATGATTCCAGATGTTGACTGCCTGCTC
TGGGCCATTGGGCGGGTCCCGAATACCAAGGACCTGAGTTTAAACAAACTGGGGATTCAAACCGATGACAAGGGTCATATCATCGTAGAC
GAATTCCAGAATACCAACGTCAAAGGCATCTATGCAGTTGGGGATGTATGTGGAAAAGCTCTTCTTACTCCAGTTGCAATAGCTGCTGGC
CGAAAACTTGCCCATCGACTTTTTGAATATAAGGAAGATTCCAAATTAGATTATAACAACATCCCAACTGTGGTCTTCAGCCACCCCCCT
ATTGGGACAGTGGGACTCACGGAAGATGAAGCCATTCATAAATATGGAATAGAAAATGTGAAGACCTATTCAACGAGCTTTACCCCGATG
TATCACGCAGTTACCAAAAGGAAAACAAAATGTGTGATGAAAATGGTCTGTGCTAACAAGGAAGAAAAGGTGGTTGGGATCCATATGCAG
GGACTTGGGTGTGATGAAATGCTGCAGGGTTTTGCTGTTGCAGTGAAGATGGGAGCAACGAAGGCAGACTTTGACAACACAGTCGCCATT
CACCCTACCTCTTCAGAAGAGCTGGTCACACTTCGTTGAGAACCAGGAGACACGTGTGGCGGGCAGTGGGACCCATAGATCTTCTGAAAT
GAAACAAATAATCACATTGACTTACTGTTTGAGTTTTATGTATTTCTTTATTTTAATCAGGATCTTCTGATAGTGGAAATTTTTAGTACA
TAATAGAACTTATTTATGGAGTTAGAAATTTGTAGTGTTATCCAGGATTGATTTTCATTTGATCACATCTCACAGTAATTAATATTTTCA
AGTTTTTTTTTTATTAACAGCTCTGTGCTAGTTTTTTTTTTCTGTTTTAGCCTCATCCCAAATATAAAGCTTTGTGAAGTACAATTAACT
TAATGTACTTGAATGAATAGAACTTGCTACTTTTTTTTTTTTTTTTTTTGAGACAGAGTTTTGCTCTCATTGCCCAGGCTGGAGTGCGGT
GGTGCTATTTCAGCTCACCACAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTTAGCCTCCCGAATAGCTGGAATTACAGGCACG
CACCACCATGCCTGACTAATTTTGTATTTTTAGTAGACATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTCAAACTCCCACCTTCAGGTG
ATCCGCCCACCTCGGCCTCCTGAGGTGCTGAGATTACAGGCGTGAGCCACTGTGCCAGCTTGCTAATTTTCACAGAAGTTGATGGCAATT
CTTCACATGTAAACAGTGCCAGTGCACAGAACCTTTATATATTTTTTGAAGCCAGTACTGTGCTCTGCATATAACAAAGCTGCTTCAAGG
ATGAGACCTTTTTCTAAAAGCATGTAATGTGAGAAGCCGGCCTGCCTTATTTTCTTTTTTCTTTTTTAATGATTAAAAATAGTTTGTGGC
AAGGCACGGTGGCTCAGGCCTGTAATTCTAGCACTTTGGGAGGCCGAGGCAGGAGGATTACTTGAGCCTACAAGTTTGAGGCCAGCATGC
ACAGCATAGCAAGACTGCATCTCTACAGAGAGTAAAAAAAATTACCCGAGTGTGGTGATGTGCATCTGTAATCTCAGCTACTTGGGAGGC
TGAGGTGAGAGGATCACTTGAGCTTGGGTGAGGTGAGGCTGCAGTGAGTCCTGATCATGCTGCTGCACTCAATCTTGGACAACAGAGCAA
GACCCTGTCTCAAAAAAAAAAAAAAAAAATATATATATATATATATATTATTTTTATGAGGTGAAGTGCATCAAACTTGGGAAAGATTTG
AGGAGGCTGGGAACCTCCTGGAAAACCACTCCTTGAAGAAAGATATGAGAGACATTTAGAAGTGATTCCTGCTTTCAGAAGGAGGTGGAT
TCAAATACATCAAAAGTCCCTTCCTCTGCTAAGTGTTTATAGTTCAATGAATAATTTCAATATTTGTATGTGTTCTTGTCATTTTATTTT

>94090_94090_2_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000305364_GSR_chr8_30569605_ENST00000414019_length(amino acids)=674AA_BP=254
MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGA
RWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEA
AWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMVNVGCVPKKVMWNTAV
HSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPH
ESQIPGASLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEV
KKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIA
AGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIH

--------------------------------------------------------------
>94090_94090_3_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000305364_GSR_chr8_30569605_ENST00000537535_length(transcript)=1863nt_BP=846nt
CACTCGGGTCGCGGGCGTTGGCAGCCGGGCGGGTGGGAGGGGCCGGAGCAAAAGTTCCGGGCGCCCGAGCCGGCTGCTCGTGCCATGGAG
CGGAGTCCCGACGTGTCCCCCGGGCCTTCCCGCTCCTTCAAGGAGGAGTTGCTCTGCGCCGTCTGCTACGACCCCTTCCGCGACGCAGTC
ACTCTGCGCTGCGGCCACAACTTCTGCCGCGGGTGCGTGAGCCGCTGCTGGGAGGTGCAGGTGTCGCCCACCTGCCCAGTGTGCAAAGAC
CGCGCGTCACCCGCCGACCTGCGCACCAACCACACCCTCAACAACCTGGTGGAGAAGCTGCTGCGCGAGGAGGCCGAGGGCGCGCGCTGG
ACCAGCTACCGCTTCTCGCGTGTCTGCCGCCTGCACCGCGGACAGCTCAGCCTCTTCTGCCTCGAGGACAAGGAGCTGCTGTGCTGCTCC
TGCCAGGCCGACCCCCGACACCAGGGGCACCGCGTGCAGCCGGTGAAGGACACTGCCCACGACTTTCGGGCCAAGTGCAGGAACATGGAG
CATGCACTGCGGGAGAAGGCCAAGGCCTTCTGGGCCATGCGGCGCTCCTATGAGGCCATCGCCAAGCACAATCAGGTGGAGGCTGCATGG
CTGGAAGGCCGGATCCGGCAGGAGTTTGATAAGCTTCGCGAGTTCTTGAGAGTGGAGGAGCAGGCCATTCTGGATGCCATGGCCGAGGAG
ACAAGGCAGAAGCAACTTCTGGCCGACGAGAAGATGAAGCAGCTCACAGAGGAGACGGAGGTGCTGGCACATGAGATCGAGCGGCTGCAG
ATGGAGATGAAGGAGGACGACGTTTCTTTTCTCATGGTGAATGTTGGATGTGTACCCAAAAAGGTAATGTGGAACACAGCTGTCCACTCT
GAATTCATGCATGATCATGCTGATTATGGCTTTCCAAGTTGTGAGGGTAAATTCAATTGGCGTGTTATTAAGGAAAAGCGGGATGCCTAT
GTGAGCCGCCTGAATGCCATCTATCAAAACAATCTCACCAAGTCCCATATAGAAATCATCCGTGGCCATGCAGCCTTCACGAGTGATCCC
AAGCCCACAATAGAGGTCAGTGGGAAAAAGTACACCGCCCCACACATCCTGATCGCCACAGGTGGTATGCCCTCCACCCCTCATGAGAGC
CAGATCCCCGGTGCCAGCTTAGGAATAACCAGCGATGGATTTTTTCAGCTGGAAGAATTGCCCGGCCGCAGCGTCATTGTTGGTGCAGGT
TACATTGCTGTGGAGATGGCAGGGATCCTGTCAGCCCTGGGTTCTAAGACATCACTGATGATACGGCATGATAAGGGGATTCAAACCGAT
GACAAGGGTCATATCATCGTAGACGAATTCCAGAATACCAACGTCAAAGGCATCTATGCAGTTGGGGATGTATGTGGAAAAGCTCTTCTT
ACTCCAGTTGCAATAGCTGCTGGCCGAAAACTTGCCCATCGACTTTTTGAATATAAGGAAGATTCCAAATTAGATTATAACAACATCCCA
ACTGTGGTCTTCAGCCACCCCCCTATTGGGACAGTGGGACTCACGGAAGATGAAGCCATTCATAAATATGGAATAGAAAATGTGAAGACC
TATTCAACGAGCTTTACCCCGATGTATCACGCAGTTACCAAAAGGAAAACAAAATGTGTGATGAAAATGGTCTGTGCTAACAAGGAAGAA
AAGGTGGTTGGGATCCATATGCAGGGACTTGGGTGTGATGAAATGCTGCAGGGTTTTGCTGTTGCAGTGAAGATGGGAGCAACGAAGGCA

>94090_94090_3_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000305364_GSR_chr8_30569605_ENST00000537535_length(amino acids)=592AA_BP=254
MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGA
RWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEA
AWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMVNVGCVPKKVMWNTAV
HSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPH
ESQIPGASLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKA
LLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANK

--------------------------------------------------------------
>94090_94090_4_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000305364_GSR_chr8_30569605_ENST00000541648_length(transcript)=1950nt_BP=846nt
CACTCGGGTCGCGGGCGTTGGCAGCCGGGCGGGTGGGAGGGGCCGGAGCAAAAGTTCCGGGCGCCCGAGCCGGCTGCTCGTGCCATGGAG
CGGAGTCCCGACGTGTCCCCCGGGCCTTCCCGCTCCTTCAAGGAGGAGTTGCTCTGCGCCGTCTGCTACGACCCCTTCCGCGACGCAGTC
ACTCTGCGCTGCGGCCACAACTTCTGCCGCGGGTGCGTGAGCCGCTGCTGGGAGGTGCAGGTGTCGCCCACCTGCCCAGTGTGCAAAGAC
CGCGCGTCACCCGCCGACCTGCGCACCAACCACACCCTCAACAACCTGGTGGAGAAGCTGCTGCGCGAGGAGGCCGAGGGCGCGCGCTGG
ACCAGCTACCGCTTCTCGCGTGTCTGCCGCCTGCACCGCGGACAGCTCAGCCTCTTCTGCCTCGAGGACAAGGAGCTGCTGTGCTGCTCC
TGCCAGGCCGACCCCCGACACCAGGGGCACCGCGTGCAGCCGGTGAAGGACACTGCCCACGACTTTCGGGCCAAGTGCAGGAACATGGAG
CATGCACTGCGGGAGAAGGCCAAGGCCTTCTGGGCCATGCGGCGCTCCTATGAGGCCATCGCCAAGCACAATCAGGTGGAGGCTGCATGG
CTGGAAGGCCGGATCCGGCAGGAGTTTGATAAGCTTCGCGAGTTCTTGAGAGTGGAGGAGCAGGCCATTCTGGATGCCATGGCCGAGGAG
ACAAGGCAGAAGCAACTTCTGGCCGACGAGAAGATGAAGCAGCTCACAGAGGAGACGGAGGTGCTGGCACATGAGATCGAGCGGCTGCAG
ATGGAGATGAAGGAGGACGACGTTTCTTTTCTCATGGTGAATGTTGGATGTGTACCCAAAAAGGTAATGTGGAACACAGCTGTCCACTCT
GAATTCATGCATGATCATGCTGATTATGGCTTTCCAAGTTGTGAGGGTAAATTCAATTGGCGTGTTATTAAGGAAAAGCGGGATGCCTAT
GTGAGCCGCCTGAATGCCATCTATCAAAACAATCTCACCAAGTCCCATATAGAAATCATCCGTGGCCATGCAGCCTTCACGAGTGATCCC
AAGCCCACAATAGAGGTCAGTGGGAAAAAGTACACCGCCCCACACATCCTGATCGCCACAGGTGGTATGCCCTCCACCCCTCATGAGAGC
CAGATCCCCGGTGCCAGCTTAGGAATAACCAGCGATGGATTTTTTCAGCTGGAAGAATTGCCCGGCCGCAGCGTCATTGTTGGTGCAGGT
TACATTGCTGTGGAGATGGCAGGGATCCTGTCAGCCCTGGGTTCTAAGACATCACTGATGATACGGCATGATAAGGTACTTAGAAGTTTT
GATTCAATGATCAGCACCAACTGCACGGAGGAGCTGGAGAACGCTGGCGTGGAGGTGCTGAAGTTCTCCCAGGGGATTCAAACCGATGAC
AAGGGTCATATCATCGTAGACGAATTCCAGAATACCAACGTCAAAGGCATCTATGCAGTTGGGGATGTATGTGGAAAAGCTCTTCTTACT
CCAGTTGCAATAGCTGCTGGCCGAAAACTTGCCCATCGACTTTTTGAATATAAGGAAGATTCCAAATTAGATTATAACAACATCCCAACT
GTGGTCTTCAGCCACCCCCCTATTGGGACAGTGGGACTCACGGAAGATGAAGCCATTCATAAATATGGAATAGAAAATGTGAAGACCTAT
TCAACGAGCTTTACCCCGATGTATCACGCAGTTACCAAAAGGAAAACAAAATGTGTGATGAAAATGGTCTGTGCTAACAAGGAAGAAAAG
GTGGTTGGGATCCATATGCAGGGACTTGGGTGTGATGAAATGCTGCAGGGTTTTGCTGTTGCAGTGAAGATGGGAGCAACGAAGGCAGAC

>94090_94090_4_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000305364_GSR_chr8_30569605_ENST00000541648_length(amino acids)=621AA_BP=254
MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGA
RWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEA
AWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMVNVGCVPKKVMWNTAV
HSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPH
ESQIPGASLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQGIQT
DDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVK

--------------------------------------------------------------
>94090_94090_5_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000305364_GSR_chr8_30569605_ENST00000546342_length(transcript)=2022nt_BP=846nt
CACTCGGGTCGCGGGCGTTGGCAGCCGGGCGGGTGGGAGGGGCCGGAGCAAAAGTTCCGGGCGCCCGAGCCGGCTGCTCGTGCCATGGAG
CGGAGTCCCGACGTGTCCCCCGGGCCTTCCCGCTCCTTCAAGGAGGAGTTGCTCTGCGCCGTCTGCTACGACCCCTTCCGCGACGCAGTC
ACTCTGCGCTGCGGCCACAACTTCTGCCGCGGGTGCGTGAGCCGCTGCTGGGAGGTGCAGGTGTCGCCCACCTGCCCAGTGTGCAAAGAC
CGCGCGTCACCCGCCGACCTGCGCACCAACCACACCCTCAACAACCTGGTGGAGAAGCTGCTGCGCGAGGAGGCCGAGGGCGCGCGCTGG
ACCAGCTACCGCTTCTCGCGTGTCTGCCGCCTGCACCGCGGACAGCTCAGCCTCTTCTGCCTCGAGGACAAGGAGCTGCTGTGCTGCTCC
TGCCAGGCCGACCCCCGACACCAGGGGCACCGCGTGCAGCCGGTGAAGGACACTGCCCACGACTTTCGGGCCAAGTGCAGGAACATGGAG
CATGCACTGCGGGAGAAGGCCAAGGCCTTCTGGGCCATGCGGCGCTCCTATGAGGCCATCGCCAAGCACAATCAGGTGGAGGCTGCATGG
CTGGAAGGCCGGATCCGGCAGGAGTTTGATAAGCTTCGCGAGTTCTTGAGAGTGGAGGAGCAGGCCATTCTGGATGCCATGGCCGAGGAG
ACAAGGCAGAAGCAACTTCTGGCCGACGAGAAGATGAAGCAGCTCACAGAGGAGACGGAGGTGCTGGCACATGAGATCGAGCGGCTGCAG
ATGGAGATGAAGGAGGACGACGTTTCTTTTCTCATGGTGAATGTTGGATGTGTACCCAAAAAGGTAATGTGGAACACAGCTGTCCACTCT
GAATTCATGCATGATCATGCTGATTATGGCTTTCCAAGTTGTGAGGGTAAATTCAATTGGCGTGTTATTAAGGAAAAGCGGGATGCCTAT
GTGAGCCGCCTGAATGCCATCTATCAAAACAATCTCACCAAGTCCCATATAGAAATCATCCGTGGCCATGCAGCCTTCACGAGTGATCCC
AAGCCCACAATAGAGGTCAGTGGGAAAAAGTACACCGCCCCACACATCCTGATCGCCACAGGTGGTATGCCCTCCACCCCTCATGAGAGC
CAGATCCCCGGTGCCAGCTTAGGAATAACCAGCGATGGATTTTTTCAGCTGGAAGAATTGCCCGGCCGCAGCGTCATTGTTGGTGCAGGT
TACATTGCTGTGGAGATGGCAGGGATCCTGTCAGCCCTGGGTTCTAAGACATCACTGATGATACGGCATGATAAGGTCAAGGAGGTTAAA
AAGACTTTGTCGGGCTTGGAAGTCAGCATGGTTACTGCAGTTCCCGGTAGGCTACCAGTCATGACCATGATTCCAGATGTTGACTGCCTG
CTCTGGGCCATTGGGCGGGTCCCGAATACCAAGGACCTGAGTTTAAACAAACTGGGGATTCAAACCGATGACAAGGGTCATATCATCGTA
GACGAATTCCAGAATACCAACGTCAAAGGCATCTATGCAGTTGGGGATGTATGTGGAAAAGCTCTTCTTACTCCAGTTGCAATAGCTGCT
GGCCGAAAACTTGCCCATCGACTTTTTGAATATAAGGAAGATTCCAAATTAGATTATAACAACATCCCAACTGTGGTCTTCAGCCACCCC
CCTATTGGGACAGTGGGACTCACGGAAGATGAAGCCATTCATAAATATGGAATAGAAAATGTGAAGACCTATTCAACGAGCTTTACCCCG
ATGTATCACGCAGTTACCAAAAGGAAAACAAAATGTGTGATGAAAATGGTCTGTGCTAACAAGGAAGAAAAGGTGGTTGGGATCCATATG
CAGGGACTTGGGTGTGATGAAATGCTGCAGGGTTTTGCTGTTGCAGTGAAGATGGGAGCAACGAAGGCAGACTTTGACAACACAGTCGCC

>94090_94090_5_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000305364_GSR_chr8_30569605_ENST00000546342_length(amino acids)=645AA_BP=254
MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGA
RWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEA
AWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMVNVGCVPKKVMWNTAV
HSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPH
ESQIPGASLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVD
CLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFS
HPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNT

--------------------------------------------------------------
>94090_94090_6_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000521253_GSR_chr8_30569605_ENST00000221130_length(transcript)=3386nt_BP=669nt
GCCATGGAGCGGAGTCCCGACGTGTCCCCCGGGCCTTCCCGCTCCTTCAAGGAGGAGTTGCTCTGCGCCGTCTGCTACGACCCCTTCCGC
GACGCAGTCACTCTGCGCTGCGGCCACAACTTCTGCCGCGGGTGCGTGAGCCGCTGCTGGGAGGTGCAGGTGTCGCCCACCTGCCCAGTG
TGCAAAGACCGCGCGTCACCCGCCGACCTGCGCACCAACCACACCCTCAACAACCTGGTGGAGAAGCTGCTGCGCGAGGAGGCCGAGGGC
GCGCGCTGGACCAGCTACCGCTTCTCGCGTGTCTGCCGCCTGCACCGCGGACAGCTCAGCCTCTTCTGCCTCGAGGACAAGGAGCTGCTG
TGCTGCTCCTGCCAGGCCGACCCCCGACACCAGGGGCACCGCGTGCAGCCGGTGAAGGACACTGCCCACGACTTTCGGGTGGAGGCTGCA
TGGCTGGAAGGCCGGATCCGGCAGGAGTTTGATAAGCTTCGCGAGTTCTTGAGAGTGGAGGAGCAGGCCATTCTGGATGCCATGGCCGAG
GAGACAAGGCAGAAGCAACTTCTGGCCGACGAGAAGATGAAGCAGCTCACAGAGGAGACGGAGGTGCTGGCACATGAGATCGAGCGGCTG
CAGATGGAGATGAAGGAGGACGACGTTTCTTTTCTCATGGTGAATGTTGGATGTGTACCCAAAAAGGTAATGTGGAACACAGCTGTCCAC
TCTGAATTCATGCATGATCATGCTGATTATGGCTTTCCAAGTTGTGAGGGTAAATTCAATTGGCGTGTTATTAAGGAAAAGCGGGATGCC
TATGTGAGCCGCCTGAATGCCATCTATCAAAACAATCTCACCAAGTCCCATATAGAAATCATCCGTGGCCATGCAGCCTTCACGAGTGAT
CCCAAGCCCACAATAGAGGTCAGTGGGAAAAAGTACACCGCCCCACACATCCTGATCGCCACAGGTGGTATGCCCTCCACCCCTCATGAG
AGCCAGATCCCCGGTGCCAGCTTAGGAATAACCAGCGATGGATTTTTTCAGCTGGAAGAATTGCCCGGCCGCAGCGTCATTGTTGGTGCA
GGTTACATTGCTGTGGAGATGGCAGGGATCCTGTCAGCCCTGGGTTCTAAGACATCACTGATGATACGGCATGATAAGGTACTTAGAAGT
TTTGATTCAATGATCAGCACCAACTGCACGGAGGAGCTGGAGAACGCTGGCGTGGAGGTGCTGAAGTTCTCCCAGGTCAAGGAGGTTAAA
AAGACTTTGTCGGGCTTGGAAGTCAGCATGGTTACTGCAGTTCCCGGTAGGCTACCAGTCATGACCATGATTCCAGATGTTGACTGCCTG
CTCTGGGCCATTGGGCGGGTCCCGAATACCAAGGACCTGAGTTTAAACAAACTGGGGATTCAAACCGATGACAAGGGTCATATCATCGTA
GACGAATTCCAGAATACCAACGTCAAAGGCATCTATGCAGTTGGGGATGTATGTGGAAAAGCTCTTCTTACTCCAGTTGCAATAGCTGCT
GGCCGAAAACTTGCCCATCGACTTTTTGAATATAAGGAAGATTCCAAATTAGATTATAACAACATCCCAACTGTGGTCTTCAGCCACCCC
CCTATTGGGACAGTGGGACTCACGGAAGATGAAGCCATTCATAAATATGGAATAGAAAATGTGAAGACCTATTCAACGAGCTTTACCCCG
ATGTATCACGCAGTTACCAAAAGGAAAACAAAATGTGTGATGAAAATGGTCTGTGCTAACAAGGAAGAAAAGGTGGTTGGGATCCATATG
CAGGGACTTGGGTGTGATGAAATGCTGCAGGGTTTTGCTGTTGCAGTGAAGATGGGAGCAACGAAGGCAGACTTTGACAACACAGTCGCC
ATTCACCCTACCTCTTCAGAAGAGCTGGTCACACTTCGTTGAGAACCAGGAGACACGTGTGGCGGGCAGTGGGACCCATAGATCTTCTGA
AATGAAACAAATAATCACATTGACTTACTGTTTGAGTTTTATGTATTTCTTTATTTTAATCAGGATCTTCTGATAGTGGAAATTTTTAGT
ACATAATAGAACTTATTTATGGAGTTAGAAATTTGTAGTGTTATCCAGGATTGATTTTCATTTGATCACATCTCACAGTAATTAATATTT
TCAAGTTTTTTTTTTATTAACAGCTCTGTGCTAGTTTTTTTTTTCTGTTTTAGCCTCATCCCAAATATAAAGCTTTGTGAAGTACAATTA
ACTTAATGTACTTGAATGAATAGAACTTGCTACTTTTTTTTTTTTTTTTTTTGAGACAGAGTTTTGCTCTCATTGCCCAGGCTGGAGTGC
GGTGGTGCTATTTCAGCTCACCACAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTTAGCCTCCCGAATAGCTGGAATTACAGGC
ACGCACCACCATGCCTGACTAATTTTGTATTTTTAGTAGACATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTCAAACTCCCACCTTCAG
GTGATCCGCCCACCTCGGCCTCCTGAGGTGCTGAGATTACAGGCGTGAGCCACTGTGCCAGCTTGCTAATTTTCACAGAAGTTGATGGCA
ATTCTTCACATGTAAACAGTGCCAGTGCACAGAACCTTTATATATTTTTTGAAGCCAGTACTGTGCTCTGCATATAACAAAGCTGCTTCA
AGGATGAGACCTTTTTCTAAAAGCATGTAATGTGAGAAGCCGGCCTGCCTTATTTTCTTTTTTCTTTTTTAATGATTAAAAATAGTTTGT
GGCAAGGCACGGTGGCTCAGGCCTGTAATTCTAGCACTTTGGGAGGCCGAGGCAGGAGGATTACTTGAGCCTACAAGTTTGAGGCCAGCA
TGCACAGCATAGCAAGACTGCATCTCTACAGAGAGTAAAAAAAATTACCCGAGTGTGGTGATGTGCATCTGTAATCTCAGCTACTTGGGA
GGCTGAGGTGAGAGGATCACTTGAGCTTGGGTGAGGTGAGGCTGCAGTGAGTCCTGATCATGCTGCTGCACTCAATCTTGGACAACAGAG
CAAGACCCTGTCTCAAAAAAAAAAAAAAAAAATATATATATATATATATATTATTTTTATGAGGTGAAGTGCATCAAACTTGGGAAAGAT
TTGAGGAGGCTGGGAACCTCCTGGAAAACCACTCCTTGAAGAAAGATATGAGAGACATTTAGAAGTGATTCCTGCTTTCAGAAGGAGGTG
GATTCAAATACATCAAAAGTCCCTTCCTCTGCTAAGTGTTTATAGTTCAATGAATAATTTCAATATTTGTATGTGTTCTTGTCATTTTAT

>94090_94090_6_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000521253_GSR_chr8_30569605_ENST00000221130_length(amino acids)=642AA_BP=222
MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGA
RWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEE
TRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAY
VSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG
YIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLL
WAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPP
IGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAI

--------------------------------------------------------------
>94090_94090_7_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000521253_GSR_chr8_30569605_ENST00000414019_length(transcript)=3385nt_BP=669nt
GCCATGGAGCGGAGTCCCGACGTGTCCCCCGGGCCTTCCCGCTCCTTCAAGGAGGAGTTGCTCTGCGCCGTCTGCTACGACCCCTTCCGC
GACGCAGTCACTCTGCGCTGCGGCCACAACTTCTGCCGCGGGTGCGTGAGCCGCTGCTGGGAGGTGCAGGTGTCGCCCACCTGCCCAGTG
TGCAAAGACCGCGCGTCACCCGCCGACCTGCGCACCAACCACACCCTCAACAACCTGGTGGAGAAGCTGCTGCGCGAGGAGGCCGAGGGC
GCGCGCTGGACCAGCTACCGCTTCTCGCGTGTCTGCCGCCTGCACCGCGGACAGCTCAGCCTCTTCTGCCTCGAGGACAAGGAGCTGCTG
TGCTGCTCCTGCCAGGCCGACCCCCGACACCAGGGGCACCGCGTGCAGCCGGTGAAGGACACTGCCCACGACTTTCGGGTGGAGGCTGCA
TGGCTGGAAGGCCGGATCCGGCAGGAGTTTGATAAGCTTCGCGAGTTCTTGAGAGTGGAGGAGCAGGCCATTCTGGATGCCATGGCCGAG
GAGACAAGGCAGAAGCAACTTCTGGCCGACGAGAAGATGAAGCAGCTCACAGAGGAGACGGAGGTGCTGGCACATGAGATCGAGCGGCTG
CAGATGGAGATGAAGGAGGACGACGTTTCTTTTCTCATGGTGAATGTTGGATGTGTACCCAAAAAGGTAATGTGGAACACAGCTGTCCAC
TCTGAATTCATGCATGATCATGCTGATTATGGCTTTCCAAGTTGTGAGGGTAAATTCAATTGGCGTGTTATTAAGGAAAAGCGGGATGCC
TATGTGAGCCGCCTGAATGCCATCTATCAAAACAATCTCACCAAGTCCCATATAGAAATCATCCGTGGCCATGCAGCCTTCACGAGTGAT
CCCAAGCCCACAATAGAGGTCAGTGGGAAAAAGTACACCGCCCCACACATCCTGATCGCCACAGGTGGTATGCCCTCCACCCCTCATGAG
AGCCAGATCCCCGGTGCCAGCTTAGGAATAACCAGCGATGGATTTTTTCAGCTGGAAGAATTGCCCGGCCGCAGCGTCATTGTTGGTGCA
GGTTACATTGCTGTGGAGATGGCAGGGATCCTGTCAGCCCTGGGTTCTAAGACATCACTGATGATACGGCATGATAAGGTACTTAGAAGT
TTTGATTCAATGATCAGCACCAACTGCACGGAGGAGCTGGAGAACGCTGGCGTGGAGGTGCTGAAGTTCTCCCAGGTCAAGGAGGTTAAA
AAGACTTTGTCGGGCTTGGAAGTCAGCATGGTTACTGCAGTTCCCGGTAGGCTACCAGTCATGACCATGATTCCAGATGTTGACTGCCTG
CTCTGGGCCATTGGGCGGGTCCCGAATACCAAGGACCTGAGTTTAAACAAACTGGGGATTCAAACCGATGACAAGGGTCATATCATCGTA
GACGAATTCCAGAATACCAACGTCAAAGGCATCTATGCAGTTGGGGATGTATGTGGAAAAGCTCTTCTTACTCCAGTTGCAATAGCTGCT
GGCCGAAAACTTGCCCATCGACTTTTTGAATATAAGGAAGATTCCAAATTAGATTATAACAACATCCCAACTGTGGTCTTCAGCCACCCC
CCTATTGGGACAGTGGGACTCACGGAAGATGAAGCCATTCATAAATATGGAATAGAAAATGTGAAGACCTATTCAACGAGCTTTACCCCG
ATGTATCACGCAGTTACCAAAAGGAAAACAAAATGTGTGATGAAAATGGTCTGTGCTAACAAGGAAGAAAAGGTGGTTGGGATCCATATG
CAGGGACTTGGGTGTGATGAAATGCTGCAGGGTTTTGCTGTTGCAGTGAAGATGGGAGCAACGAAGGCAGACTTTGACAACACAGTCGCC
ATTCACCCTACCTCTTCAGAAGAGCTGGTCACACTTCGTTGAGAACCAGGAGACACGTGTGGCGGGCAGTGGGACCCATAGATCTTCTGA
AATGAAACAAATAATCACATTGACTTACTGTTTGAGTTTTATGTATTTCTTTATTTTAATCAGGATCTTCTGATAGTGGAAATTTTTAGT
ACATAATAGAACTTATTTATGGAGTTAGAAATTTGTAGTGTTATCCAGGATTGATTTTCATTTGATCACATCTCACAGTAATTAATATTT
TCAAGTTTTTTTTTTATTAACAGCTCTGTGCTAGTTTTTTTTTTCTGTTTTAGCCTCATCCCAAATATAAAGCTTTGTGAAGTACAATTA
ACTTAATGTACTTGAATGAATAGAACTTGCTACTTTTTTTTTTTTTTTTTTTGAGACAGAGTTTTGCTCTCATTGCCCAGGCTGGAGTGC
GGTGGTGCTATTTCAGCTCACCACAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTTAGCCTCCCGAATAGCTGGAATTACAGGC
ACGCACCACCATGCCTGACTAATTTTGTATTTTTAGTAGACATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTCAAACTCCCACCTTCAG
GTGATCCGCCCACCTCGGCCTCCTGAGGTGCTGAGATTACAGGCGTGAGCCACTGTGCCAGCTTGCTAATTTTCACAGAAGTTGATGGCA
ATTCTTCACATGTAAACAGTGCCAGTGCACAGAACCTTTATATATTTTTTGAAGCCAGTACTGTGCTCTGCATATAACAAAGCTGCTTCA
AGGATGAGACCTTTTTCTAAAAGCATGTAATGTGAGAAGCCGGCCTGCCTTATTTTCTTTTTTCTTTTTTAATGATTAAAAATAGTTTGT
GGCAAGGCACGGTGGCTCAGGCCTGTAATTCTAGCACTTTGGGAGGCCGAGGCAGGAGGATTACTTGAGCCTACAAGTTTGAGGCCAGCA
TGCACAGCATAGCAAGACTGCATCTCTACAGAGAGTAAAAAAAATTACCCGAGTGTGGTGATGTGCATCTGTAATCTCAGCTACTTGGGA
GGCTGAGGTGAGAGGATCACTTGAGCTTGGGTGAGGTGAGGCTGCAGTGAGTCCTGATCATGCTGCTGCACTCAATCTTGGACAACAGAG
CAAGACCCTGTCTCAAAAAAAAAAAAAAAAAATATATATATATATATATATTATTTTTATGAGGTGAAGTGCATCAAACTTGGGAAAGAT
TTGAGGAGGCTGGGAACCTCCTGGAAAACCACTCCTTGAAGAAAGATATGAGAGACATTTAGAAGTGATTCCTGCTTTCAGAAGGAGGTG
GATTCAAATACATCAAAAGTCCCTTCCTCTGCTAAGTGTTTATAGTTCAATGAATAATTTCAATATTTGTATGTGTTCTTGTCATTTTAT

>94090_94090_7_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000521253_GSR_chr8_30569605_ENST00000414019_length(amino acids)=642AA_BP=222
MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGA
RWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEE
TRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAY
VSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG
YIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLL
WAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPP
IGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAI

--------------------------------------------------------------
>94090_94090_8_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000521253_GSR_chr8_30569605_ENST00000537535_length(transcript)=1686nt_BP=669nt
GCCATGGAGCGGAGTCCCGACGTGTCCCCCGGGCCTTCCCGCTCCTTCAAGGAGGAGTTGCTCTGCGCCGTCTGCTACGACCCCTTCCGC
GACGCAGTCACTCTGCGCTGCGGCCACAACTTCTGCCGCGGGTGCGTGAGCCGCTGCTGGGAGGTGCAGGTGTCGCCCACCTGCCCAGTG
TGCAAAGACCGCGCGTCACCCGCCGACCTGCGCACCAACCACACCCTCAACAACCTGGTGGAGAAGCTGCTGCGCGAGGAGGCCGAGGGC
GCGCGCTGGACCAGCTACCGCTTCTCGCGTGTCTGCCGCCTGCACCGCGGACAGCTCAGCCTCTTCTGCCTCGAGGACAAGGAGCTGCTG
TGCTGCTCCTGCCAGGCCGACCCCCGACACCAGGGGCACCGCGTGCAGCCGGTGAAGGACACTGCCCACGACTTTCGGGTGGAGGCTGCA
TGGCTGGAAGGCCGGATCCGGCAGGAGTTTGATAAGCTTCGCGAGTTCTTGAGAGTGGAGGAGCAGGCCATTCTGGATGCCATGGCCGAG
GAGACAAGGCAGAAGCAACTTCTGGCCGACGAGAAGATGAAGCAGCTCACAGAGGAGACGGAGGTGCTGGCACATGAGATCGAGCGGCTG
CAGATGGAGATGAAGGAGGACGACGTTTCTTTTCTCATGGTGAATGTTGGATGTGTACCCAAAAAGGTAATGTGGAACACAGCTGTCCAC
TCTGAATTCATGCATGATCATGCTGATTATGGCTTTCCAAGTTGTGAGGGTAAATTCAATTGGCGTGTTATTAAGGAAAAGCGGGATGCC
TATGTGAGCCGCCTGAATGCCATCTATCAAAACAATCTCACCAAGTCCCATATAGAAATCATCCGTGGCCATGCAGCCTTCACGAGTGAT
CCCAAGCCCACAATAGAGGTCAGTGGGAAAAAGTACACCGCCCCACACATCCTGATCGCCACAGGTGGTATGCCCTCCACCCCTCATGAG
AGCCAGATCCCCGGTGCCAGCTTAGGAATAACCAGCGATGGATTTTTTCAGCTGGAAGAATTGCCCGGCCGCAGCGTCATTGTTGGTGCA
GGTTACATTGCTGTGGAGATGGCAGGGATCCTGTCAGCCCTGGGTTCTAAGACATCACTGATGATACGGCATGATAAGGGGATTCAAACC
GATGACAAGGGTCATATCATCGTAGACGAATTCCAGAATACCAACGTCAAAGGCATCTATGCAGTTGGGGATGTATGTGGAAAAGCTCTT
CTTACTCCAGTTGCAATAGCTGCTGGCCGAAAACTTGCCCATCGACTTTTTGAATATAAGGAAGATTCCAAATTAGATTATAACAACATC
CCAACTGTGGTCTTCAGCCACCCCCCTATTGGGACAGTGGGACTCACGGAAGATGAAGCCATTCATAAATATGGAATAGAAAATGTGAAG
ACCTATTCAACGAGCTTTACCCCGATGTATCACGCAGTTACCAAAAGGAAAACAAAATGTGTGATGAAAATGGTCTGTGCTAACAAGGAA
GAAAAGGTGGTTGGGATCCATATGCAGGGACTTGGGTGTGATGAAATGCTGCAGGGTTTTGCTGTTGCAGTGAAGATGGGAGCAACGAAG

>94090_94090_8_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000521253_GSR_chr8_30569605_ENST00000537535_length(amino acids)=560AA_BP=222
MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGA
RWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEE
TRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAY
VSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG
YIAVEMAGILSALGSKTSLMIRHDKGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIP
TVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKA

--------------------------------------------------------------
>94090_94090_9_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000521253_GSR_chr8_30569605_ENST00000541648_length(transcript)=1773nt_BP=669nt
GCCATGGAGCGGAGTCCCGACGTGTCCCCCGGGCCTTCCCGCTCCTTCAAGGAGGAGTTGCTCTGCGCCGTCTGCTACGACCCCTTCCGC
GACGCAGTCACTCTGCGCTGCGGCCACAACTTCTGCCGCGGGTGCGTGAGCCGCTGCTGGGAGGTGCAGGTGTCGCCCACCTGCCCAGTG
TGCAAAGACCGCGCGTCACCCGCCGACCTGCGCACCAACCACACCCTCAACAACCTGGTGGAGAAGCTGCTGCGCGAGGAGGCCGAGGGC
GCGCGCTGGACCAGCTACCGCTTCTCGCGTGTCTGCCGCCTGCACCGCGGACAGCTCAGCCTCTTCTGCCTCGAGGACAAGGAGCTGCTG
TGCTGCTCCTGCCAGGCCGACCCCCGACACCAGGGGCACCGCGTGCAGCCGGTGAAGGACACTGCCCACGACTTTCGGGTGGAGGCTGCA
TGGCTGGAAGGCCGGATCCGGCAGGAGTTTGATAAGCTTCGCGAGTTCTTGAGAGTGGAGGAGCAGGCCATTCTGGATGCCATGGCCGAG
GAGACAAGGCAGAAGCAACTTCTGGCCGACGAGAAGATGAAGCAGCTCACAGAGGAGACGGAGGTGCTGGCACATGAGATCGAGCGGCTG
CAGATGGAGATGAAGGAGGACGACGTTTCTTTTCTCATGGTGAATGTTGGATGTGTACCCAAAAAGGTAATGTGGAACACAGCTGTCCAC
TCTGAATTCATGCATGATCATGCTGATTATGGCTTTCCAAGTTGTGAGGGTAAATTCAATTGGCGTGTTATTAAGGAAAAGCGGGATGCC
TATGTGAGCCGCCTGAATGCCATCTATCAAAACAATCTCACCAAGTCCCATATAGAAATCATCCGTGGCCATGCAGCCTTCACGAGTGAT
CCCAAGCCCACAATAGAGGTCAGTGGGAAAAAGTACACCGCCCCACACATCCTGATCGCCACAGGTGGTATGCCCTCCACCCCTCATGAG
AGCCAGATCCCCGGTGCCAGCTTAGGAATAACCAGCGATGGATTTTTTCAGCTGGAAGAATTGCCCGGCCGCAGCGTCATTGTTGGTGCA
GGTTACATTGCTGTGGAGATGGCAGGGATCCTGTCAGCCCTGGGTTCTAAGACATCACTGATGATACGGCATGATAAGGTACTTAGAAGT
TTTGATTCAATGATCAGCACCAACTGCACGGAGGAGCTGGAGAACGCTGGCGTGGAGGTGCTGAAGTTCTCCCAGGGGATTCAAACCGAT
GACAAGGGTCATATCATCGTAGACGAATTCCAGAATACCAACGTCAAAGGCATCTATGCAGTTGGGGATGTATGTGGAAAAGCTCTTCTT
ACTCCAGTTGCAATAGCTGCTGGCCGAAAACTTGCCCATCGACTTTTTGAATATAAGGAAGATTCCAAATTAGATTATAACAACATCCCA
ACTGTGGTCTTCAGCCACCCCCCTATTGGGACAGTGGGACTCACGGAAGATGAAGCCATTCATAAATATGGAATAGAAAATGTGAAGACC
TATTCAACGAGCTTTACCCCGATGTATCACGCAGTTACCAAAAGGAAAACAAAATGTGTGATGAAAATGGTCTGTGCTAACAAGGAAGAA
AAGGTGGTTGGGATCCATATGCAGGGACTTGGGTGTGATGAAATGCTGCAGGGTTTTGCTGTTGCAGTGAAGATGGGAGCAACGAAGGCA

>94090_94090_9_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000521253_GSR_chr8_30569605_ENST00000541648_length(amino acids)=589AA_BP=222
MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGA
RWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEE
TRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAY
VSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG
YIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLT
PVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEK

--------------------------------------------------------------
>94090_94090_10_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000521253_GSR_chr8_30569605_ENST00000546342_length(transcript)=1845nt_BP=669nt
GCCATGGAGCGGAGTCCCGACGTGTCCCCCGGGCCTTCCCGCTCCTTCAAGGAGGAGTTGCTCTGCGCCGTCTGCTACGACCCCTTCCGC
GACGCAGTCACTCTGCGCTGCGGCCACAACTTCTGCCGCGGGTGCGTGAGCCGCTGCTGGGAGGTGCAGGTGTCGCCCACCTGCCCAGTG
TGCAAAGACCGCGCGTCACCCGCCGACCTGCGCACCAACCACACCCTCAACAACCTGGTGGAGAAGCTGCTGCGCGAGGAGGCCGAGGGC
GCGCGCTGGACCAGCTACCGCTTCTCGCGTGTCTGCCGCCTGCACCGCGGACAGCTCAGCCTCTTCTGCCTCGAGGACAAGGAGCTGCTG
TGCTGCTCCTGCCAGGCCGACCCCCGACACCAGGGGCACCGCGTGCAGCCGGTGAAGGACACTGCCCACGACTTTCGGGTGGAGGCTGCA
TGGCTGGAAGGCCGGATCCGGCAGGAGTTTGATAAGCTTCGCGAGTTCTTGAGAGTGGAGGAGCAGGCCATTCTGGATGCCATGGCCGAG
GAGACAAGGCAGAAGCAACTTCTGGCCGACGAGAAGATGAAGCAGCTCACAGAGGAGACGGAGGTGCTGGCACATGAGATCGAGCGGCTG
CAGATGGAGATGAAGGAGGACGACGTTTCTTTTCTCATGGTGAATGTTGGATGTGTACCCAAAAAGGTAATGTGGAACACAGCTGTCCAC
TCTGAATTCATGCATGATCATGCTGATTATGGCTTTCCAAGTTGTGAGGGTAAATTCAATTGGCGTGTTATTAAGGAAAAGCGGGATGCC
TATGTGAGCCGCCTGAATGCCATCTATCAAAACAATCTCACCAAGTCCCATATAGAAATCATCCGTGGCCATGCAGCCTTCACGAGTGAT
CCCAAGCCCACAATAGAGGTCAGTGGGAAAAAGTACACCGCCCCACACATCCTGATCGCCACAGGTGGTATGCCCTCCACCCCTCATGAG
AGCCAGATCCCCGGTGCCAGCTTAGGAATAACCAGCGATGGATTTTTTCAGCTGGAAGAATTGCCCGGCCGCAGCGTCATTGTTGGTGCA
GGTTACATTGCTGTGGAGATGGCAGGGATCCTGTCAGCCCTGGGTTCTAAGACATCACTGATGATACGGCATGATAAGGTCAAGGAGGTT
AAAAAGACTTTGTCGGGCTTGGAAGTCAGCATGGTTACTGCAGTTCCCGGTAGGCTACCAGTCATGACCATGATTCCAGATGTTGACTGC
CTGCTCTGGGCCATTGGGCGGGTCCCGAATACCAAGGACCTGAGTTTAAACAAACTGGGGATTCAAACCGATGACAAGGGTCATATCATC
GTAGACGAATTCCAGAATACCAACGTCAAAGGCATCTATGCAGTTGGGGATGTATGTGGAAAAGCTCTTCTTACTCCAGTTGCAATAGCT
GCTGGCCGAAAACTTGCCCATCGACTTTTTGAATATAAGGAAGATTCCAAATTAGATTATAACAACATCCCAACTGTGGTCTTCAGCCAC
CCCCCTATTGGGACAGTGGGACTCACGGAAGATGAAGCCATTCATAAATATGGAATAGAAAATGTGAAGACCTATTCAACGAGCTTTACC
CCGATGTATCACGCAGTTACCAAAAGGAAAACAAAATGTGTGATGAAAATGGTCTGTGCTAACAAGGAAGAAAAGGTGGTTGGGATCCAT
ATGCAGGGACTTGGGTGTGATGAAATGCTGCAGGGTTTTGCTGTTGCAGTGAAGATGGGAGCAACGAAGGCAGACTTTGACAACACAGTC

>94090_94090_10_TRIM35-GSR_TRIM35_chr8_27151597_ENST00000521253_GSR_chr8_30569605_ENST00000546342_length(amino acids)=613AA_BP=222
MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGA
RWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEE
TRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAY
VSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG
YIAVEMAGILSALGSKTSLMIRHDKVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIV
DEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTP

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for TRIM35-GSR

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for TRIM35-GSR

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for TRIM35-GSR

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source