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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TRIM37-DNAH17 (FusionGDB2 ID:94097)

Fusion Gene Summary for TRIM37-DNAH17

check button Fusion gene summary
Fusion gene informationFusion gene name: TRIM37-DNAH17
Fusion gene ID: 94097
HgeneTgene
Gene symbol

TRIM37

DNAH17

Gene ID

4591

8632

Gene nametripartite motif containing 37dynein axonemal heavy chain 17
SynonymsMUL|POB1|TEF3DNAHL1|DNEL2|SPGF39
Cytomap

17q22

17q25.3

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase TRIM37RING-B-box-coiled-coil proteinRING-type E3 ubiquitin transferase TRIM37mulibrey nanism proteindynein heavy chain 17, axonemalaxonemal beta dynein heavy chain 17axonemal dynein heavy chain-like protein 1ciliary dynein heavy chain 17ciliary dynein heavy chain-like protein 1dynein light chain 2, axonemaldynein, axonemal, heavy polypeptide 17
Modification date2020031320200320
UniProtAcc.

Q9UFH2

Ensembl transtripts involved in fusion geneENST00000262294, ENST00000376149, 
ENST00000393065, ENST00000393066, 
ENST00000584889, 		ENST00000586052, 
ENST00000389840, ENST00000585328, 
Fusion gene scores* DoF score9 X 9 X 6=48615 X 16 X 11=2640
# samples 1119
** MAII scorelog2(11/486*10)=-2.14345279008112
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/2640*10)=-3.79646660591487
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TRIM37 [Title/Abstract] AND DNAH17 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTRIM37(57161363)-DNAH17(76441762), # samples:3
Anticipated loss of major functional domain due to fusion event.TRIM37-DNAH17 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTRIM37

GO:0000122

negative regulation of transcription by RNA polymerase II

25470042

HgeneTRIM37

GO:0032088

negative regulation of NF-kappaB transcription factor activity

11279055

HgeneTRIM37

GO:0035518

histone H2A monoubiquitination

25470042

HgeneTRIM37

GO:0036353

histone H2A-K119 monoubiquitination

25470042

HgeneTRIM37

GO:0051091

positive regulation of DNA-binding transcription factor activity

23077300

HgeneTRIM37

GO:0051092

positive regulation of NF-kappaB transcription factor activity

23077300

HgeneTRIM37

GO:0051865

protein autoubiquitination

15885686

HgeneTRIM37

GO:0070842

aggresome assembly

15885686


check buttonFusion gene breakpoints across TRIM37 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DNAH17 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-8590-01ATRIM37chr17

57161363

-DNAH17chr17

76441762

-


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Fusion Gene ORF analysis for TRIM37-DNAH17

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000262294ENST00000586052TRIM37chr17

57161363

-DNAH17chr17

76441762

-
5CDS-5UTRENST00000376149ENST00000586052TRIM37chr17

57161363

-DNAH17chr17

76441762

-
5CDS-5UTRENST00000393065ENST00000586052TRIM37chr17

57161363

-DNAH17chr17

76441762

-
5CDS-5UTRENST00000393066ENST00000586052TRIM37chr17

57161363

-DNAH17chr17

76441762

-
Frame-shiftENST00000376149ENST00000389840TRIM37chr17

57161363

-DNAH17chr17

76441762

-
Frame-shiftENST00000376149ENST00000585328TRIM37chr17

57161363

-DNAH17chr17

76441762

-
In-frameENST00000262294ENST00000389840TRIM37chr17

57161363

-DNAH17chr17

76441762

-
In-frameENST00000262294ENST00000585328TRIM37chr17

57161363

-DNAH17chr17

76441762

-
In-frameENST00000393065ENST00000389840TRIM37chr17

57161363

-DNAH17chr17

76441762

-
In-frameENST00000393065ENST00000585328TRIM37chr17

57161363

-DNAH17chr17

76441762

-
In-frameENST00000393066ENST00000389840TRIM37chr17

57161363

-DNAH17chr17

76441762

-
In-frameENST00000393066ENST00000585328TRIM37chr17

57161363

-DNAH17chr17

76441762

-
intron-3CDSENST00000584889ENST00000389840TRIM37chr17

57161363

-DNAH17chr17

76441762

-
intron-3CDSENST00000584889ENST00000585328TRIM37chr17

57161363

-DNAH17chr17

76441762

-
intron-5UTRENST00000584889ENST00000586052TRIM37chr17

57161363

-DNAH17chr17

76441762

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000393066TRIM37chr1757161363-ENST00000389840DNAH17chr1776441762-33278293433117924
ENST00000393066TRIM37chr1757161363-ENST00000585328DNAH17chr1776441762-32168293433006887
ENST00000262294TRIM37chr1757161363-ENST00000389840DNAH17chr1776441762-31276291432917924
ENST00000262294TRIM37chr1757161363-ENST00000585328DNAH17chr1776441762-30166291432806887
ENST00000393065TRIM37chr1757161363-ENST00000389840DNAH17chr1776441762-31306322482920890
ENST00000393065TRIM37chr1757161363-ENST00000585328DNAH17chr1776441762-30196322482809853

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000393066ENST00000389840TRIM37chr1757161363-DNAH17chr1776441762-0.0023206310.9976794
ENST00000393066ENST00000585328TRIM37chr1757161363-DNAH17chr1776441762-0.0022910130.9977089
ENST00000262294ENST00000389840TRIM37chr1757161363-DNAH17chr1776441762-0.0025578330.9974421
ENST00000262294ENST00000585328TRIM37chr1757161363-DNAH17chr1776441762-0.0024478190.9975522
ENST00000393065ENST00000389840TRIM37chr1757161363-DNAH17chr1776441762-0.0047765870.99522346
ENST00000393065ENST00000585328TRIM37chr1757161363-DNAH17chr1776441762-0.0057490390.994251

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Fusion Genomic Features for TRIM37-DNAH17


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TRIM37-DNAH17


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:57161363/chr17:76441762)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.DNAH17

Q9UFH2

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (Probable). Plays a major role in sperm motility, implicated in sperm flagellar assembly and beating (PubMed:31178125). {ECO:0000269|PubMed:31178125, ECO:0000305|PubMed:31178125}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRIM37chr17:57161363chr17:76441762ENST00000262294-52415_55123965.0Zinc fingerRING-type%3B degenerate
HgeneTRIM37chr17:57161363chr17:76441762ENST00000393066-52515_55123965.0Zinc fingerRING-type%3B degenerate
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068813842_406837234486.0RegionAAA 6
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068814147_418237234486.0RepeatNote=TPR 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRIM37chr17:57161363chr17:76441762ENST00000262294-524132_234123965.0Coiled coilOntology_term=ECO:0000255
HgeneTRIM37chr17:57161363chr17:76441762ENST00000262294-524419_450123965.0Coiled coilOntology_term=ECO:0000255
HgeneTRIM37chr17:57161363chr17:76441762ENST00000262294-524673_700123965.0Coiled coilOntology_term=ECO:0000255
HgeneTRIM37chr17:57161363chr17:76441762ENST00000376149-523132_2341804.0Coiled coilOntology_term=ECO:0000255
HgeneTRIM37chr17:57161363chr17:76441762ENST00000376149-523419_4501804.0Coiled coilOntology_term=ECO:0000255
HgeneTRIM37chr17:57161363chr17:76441762ENST00000376149-523673_7001804.0Coiled coilOntology_term=ECO:0000255
HgeneTRIM37chr17:57161363chr17:76441762ENST00000393066-525132_234123965.0Coiled coilOntology_term=ECO:0000255
HgeneTRIM37chr17:57161363chr17:76441762ENST00000393066-525419_450123965.0Coiled coilOntology_term=ECO:0000255
HgeneTRIM37chr17:57161363chr17:76441762ENST00000393066-525673_700123965.0Coiled coilOntology_term=ECO:0000255
HgeneTRIM37chr17:57161363chr17:76441762ENST00000262294-524534_540123965.0Compositional biasNote=Poly-Ser
HgeneTRIM37chr17:57161363chr17:76441762ENST00000262294-524578_581123965.0Compositional biasNote=Poly-Ala
HgeneTRIM37chr17:57161363chr17:76441762ENST00000376149-523534_5401804.0Compositional biasNote=Poly-Ser
HgeneTRIM37chr17:57161363chr17:76441762ENST00000376149-523578_5811804.0Compositional biasNote=Poly-Ala
HgeneTRIM37chr17:57161363chr17:76441762ENST00000393066-525534_540123965.0Compositional biasNote=Poly-Ser
HgeneTRIM37chr17:57161363chr17:76441762ENST00000393066-525578_581123965.0Compositional biasNote=Poly-Ala
HgeneTRIM37chr17:57161363chr17:76441762ENST00000262294-524276_403123965.0DomainMATH
HgeneTRIM37chr17:57161363chr17:76441762ENST00000376149-523276_4031804.0DomainMATH
HgeneTRIM37chr17:57161363chr17:76441762ENST00000393066-525276_403123965.0DomainMATH
HgeneTRIM37chr17:57161363chr17:76441762ENST00000262294-52490_132123965.0Zinc fingerB box-type
HgeneTRIM37chr17:57161363chr17:76441762ENST00000376149-52315_551804.0Zinc fingerRING-type%3B degenerate
HgeneTRIM37chr17:57161363chr17:76441762ENST00000376149-52390_1321804.0Zinc fingerB box-type
HgeneTRIM37chr17:57161363chr17:76441762ENST00000393066-52590_132123965.0Zinc fingerB box-type
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068813027_308637234486.0Coiled coilOntology_term=ECO:0000255
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068813257_330937234486.0Coiled coilOntology_term=ECO:0000255
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068811847_185437234486.0Nucleotide bindingATP
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068812128_213537234486.0Nucleotide bindingATP
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068812455_246237234486.0Nucleotide bindingATP
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068812801_280837234486.0Nucleotide bindingATP
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068811809_203037234486.0RegionAAA 1
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068811_180837234486.0RegionStem
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068812090_231137234486.0RegionAAA 2
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068812417_266537234486.0RegionAAA 3
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068812763_301237234486.0RegionAAA 4
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068813027_331337234486.0RegionStalk
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068813405_363237234486.0RegionAAA 5
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068811019_105237234486.0RepeatNote=TPR 1
TgeneDNAH17chr17:57161363chr17:76441762ENST0000038984068811702_173637234486.0RepeatNote=TPR 2


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Fusion Gene Sequence for TRIM37-DNAH17


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>94097_94097_1_TRIM37-DNAH17_TRIM37_chr17_57161363_ENST00000262294_DNAH17_chr17_76441762_ENST00000389840_length(transcript)=3127nt_BP=629nt
AGCCGGGAGAAAGGAGCTGCGGCCACCGTTCGCCCTACTTCTGCGCCTCGGGGCGGGCGCGCCGGTAAAAATGGCGAAATGGGGGTAGGC
GGCGCTGGACCTGAAGAGATGGGGCGCGCAGGTGGGGCGGTTGTCAGAGCCCCCTGACGTGGGCGCCGGGCTTTTATCGGCGATTTGATC
TGGCGACCTCGGGCCGGCGCCTAAGAGGTCAGACTGCGGAGCCTGCGGGTCGCCAGCGGCCCCGCCGAGAGCCGGAGGCAATGGATGAAC
AGAGCGTGGAGAGCATTGCTGAGGTTTTCCGATGTTTCATTTGTATGGAGAAATTGCGGGATGCACGCCTGTGTCCTCATTGCTCCAAAC
TGTGTTGTTTCAGCTGTATTAGGCGCTGGCTGACAGAGCAGAGAGCTCAATGTCCTCATTGCCGTGCTCCACTCCAGCTACGAGAACTAG
TAAATTGTCGTTGGGCAGAAGAAGTAACACAACAGCTTGATACTCTTCAACTCTGCAGTCTCACCAAACATGAAGAAAATGAAAAGGACA
AATGTGAAAATCACCATGAAAAACTTAGTGTATTTTGCTGGACTTGTAAGAAGTGTATCTGCCATCAGTGTGCACTTTGGGGAGGAATGG
TCCTGTCCATGAAGAAGGAGCTGAACCCAGTGGAGCTGGATTTCCTCCTGCGGTTCCCTTTTAAGGCCGGAGTGGTCTCACCAGTGGACT
TCCTCCAGCATCAAGGCTGGGGCGGGATCAAGGCCCTCTCGGAGATGGATGAGTTCAAAAATCTGGACAGTGACATCGAAGGATCTGCCA
AGCGCTGGAAAAAGCTGGTGGAGTCGGAAGCCCCCGAGAAGGAGATCTTCCCCAAGGAGTGGAAGAACAAGACGGCCCTGCAGAAGCTGT
GCATGGTGCGCTGCCTGCGGCCAGATCGCATGACCTACGCTATCAAGAACTTCGTGGAGGAAAAGATGGGCAGCAAGTTCGTGGAAGGCC
GGAGTGTTGAGTTTTCTAAGTCCTACGAGGAGAGCAGCCCCTCCACGTCAATCTTCTTCATCCTCTCCCCGGGGGTTGACCCCTTGAAAG
ACGTGGAAGCCCTGGGAAAAAAACTAGGGTTTACCATAGACAATGGAAAACTCCATAATGTGTCCCTGGGGCAGGGACAAGAGGTGGTGG
CTGAGAACGCCCTGGACGTGGCTGCAGAGAAAGGACACTGGGTCATTCTGCAGGTACGAGGGGGCCAGCACTGCAGGAATATCCACCTGG
TGGCCCGGTGGCTGGGAACACTGGACAAGAAGCTGGAGCACTACAGCACGGGCAGCCATGAGGACTACCGGGTGTTCATCAGCGCGGAGC
CTGCCCCCAGCCCCGAGACCCACATCATCCCCCAGGGCATTCTGGAGAACGCCATCAAGATCACCAACGAGCCCCCCACGGGCATGCACG
CCAACTTGCACAAGGCCCTGGACCTGTTCACCCAGGACACCCTGGAGATGTGCACCAAGGAGATGGAGTTCAAGTGCATGCTCTTCGCCC
TGTGCTACTTCCACGCTGTGGTGGCAGAGAGGCGCAAGTTCGGCGCCCAGGGCTGGAACCGGTCGTACCCCTTCAACAACGGGGACCTCA
CCATCTCCATCAACGTGCTCTACAACTACCTGGAGGCCAACCCCAAGGTGCCCTGGGACGATCTCCGCTACCTTTTTGGTGAAATCATGT
ATGGCGGCCACATCACAGATGACTGGGACCGTCGGCTGTGCAGGACCTACCTGGCTGAATACATCCGGACGGAGATGCTGGAGGGAGACG
TCCTGCTGGCCCCCGGCTTTCAGATCCCCCCCAACCTGGACTACAAGGGTTACCACGAATACATCGATGAGAACCTGCCCCCTGAGAGTC
CCTATCTGTATGGCCTGCACCCCAACGCAGAGATTGGCTTTCTGACGGTCACCTCAGAGAAGCTGTTCCGCACTGTCCTGGAAATGCAGC
CAAAAGAGACGGACTCGGGGGCAGGCACGGGAGTGTCCCGCGAGGAGAAGGCAGGATCTTTGAAACTGCTCCCAAGCGAGAGGAAGGGGG
AGGATCTAGAACTGAGGAGGGGGGGCTGTCCGGGGACTGGCTTCCAGGTGAAGGCCGTGCTGGACGACATCCTGGAGAAGATTCCGGAGA
CTTTCAACATGGCTGAGATCATGGCAAAGGCAGCGGAAAAGACCCCCTACGTGGTAGTCGCCTTTCAAGAATGTGAAAGAATGAACATCC
TGACCAACGAAATGCGCCGTTCGCTCAAGGAGCTGAACCTGGGGCTGAAGGGAGAACTGACCATCACGACCGACGTGGAAGATCTGTCCA
CGGCTCTCTTCTATGACACCGTGCCTGATACGTGGGTGGCCCGGGCCTACCCCTCCATGATGGGCCTGGCGGCCTGGTACGCAGACCTGC
TGCTCCGCATCAGGGAACTCGAGGCCTGGACGACAGACTTTGCCCTGCCCACCACCGTGTGGCTGGCCGGCTTCTTCAACCCCCAGTCGT
TCCTCACGGCCATCATGCAGTCCATGGCCAGGAAGAACGAGTGGCCCCTGGACAAGATGTGTCTGTCTGTCGAGGTGACCAAGAAAAACC
GAGAGGACATGACCGCTCCTCCGCGAGAGGGCTCCTACGTGTACGGACTCTTCATGGAAGGGGCTCGCTGGGACACCCAGACTGGAGTCA
TCGCTGAAGCGCGGCTGAAAGAGCTGACCCCGGCCATGCCTGTCATCTTCATCAAGGCCATTCCTGTGGACCGCATGGAGACCAAGAACA
TCTATGAGTGTCCCGTGTACAAAACACGCATCCGCGGCCCCACCTATGTCTGGACCTTTAACTTGAAGACCAAAGAGAAGGCAGCGAAGT
GGATCCTGGCAGCCGTGGCGCTGCTCCTACAGGTTTAGCTCGCTCCTGCCTCACAGCCCACACTCCCTGGGGCTGGACCACAACTCAGCC
CTTCACCTGTGCACCTGTGACTTATTCTTTACAGGAACTGGTGGTGGTTTTTCGTTCTCTTAAATAATCAGGTGCTTTGTAACCAAGCAC

>94097_94097_1_TRIM37-DNAH17_TRIM37_chr17_57161363_ENST00000262294_DNAH17_chr17_76441762_ENST00000389840_length(amino acids)=924AA_BP=162
MTWAPGFYRRFDLATSGRRLRGQTAEPAGRQRPRREPEAMDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQC
PHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMVLSMKKELNPVELDFLLR
FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNF
VEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ
VRGGQHCRNIHLVARWLGTLDKKLEHYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMC
TKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYL
AEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKA
GSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKG
ELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLD
KMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVW

--------------------------------------------------------------
>94097_94097_2_TRIM37-DNAH17_TRIM37_chr17_57161363_ENST00000262294_DNAH17_chr17_76441762_ENST00000585328_length(transcript)=3016nt_BP=629nt
AGCCGGGAGAAAGGAGCTGCGGCCACCGTTCGCCCTACTTCTGCGCCTCGGGGCGGGCGCGCCGGTAAAAATGGCGAAATGGGGGTAGGC
GGCGCTGGACCTGAAGAGATGGGGCGCGCAGGTGGGGCGGTTGTCAGAGCCCCCTGACGTGGGCGCCGGGCTTTTATCGGCGATTTGATC
TGGCGACCTCGGGCCGGCGCCTAAGAGGTCAGACTGCGGAGCCTGCGGGTCGCCAGCGGCCCCGCCGAGAGCCGGAGGCAATGGATGAAC
AGAGCGTGGAGAGCATTGCTGAGGTTTTCCGATGTTTCATTTGTATGGAGAAATTGCGGGATGCACGCCTGTGTCCTCATTGCTCCAAAC
TGTGTTGTTTCAGCTGTATTAGGCGCTGGCTGACAGAGCAGAGAGCTCAATGTCCTCATTGCCGTGCTCCACTCCAGCTACGAGAACTAG
TAAATTGTCGTTGGGCAGAAGAAGTAACACAACAGCTTGATACTCTTCAACTCTGCAGTCTCACCAAACATGAAGAAAATGAAAAGGACA
AATGTGAAAATCACCATGAAAAACTTAGTGTATTTTGCTGGACTTGTAAGAAGTGTATCTGCCATCAGTGTGCACTTTGGGGAGGAATGG
TCCTGTCCATGAAGAAGGAGCTGAACCCAGTGGAGCTGGATTTCCTCCTGCGGTTCCCTTTTAAGGCCGGAGTGGTCTCACCAGTGGACT
TCCTCCAGCATCAAGGCTGGGGCGGGATCAAGGCCCTCTCGGAGATGGATGAGTTCAAAAATCTGGACAGTGACATCGAAGGATCTGCCA
AGCGCTGGAAAAAGCTGGTGGAGTCGGAAGCCCCCGAGAAGGAGATCTTCCCCAAGGAGTGGAAGAACAAGACGGCCCTGCAGAAGCTGT
GCATGGTGCGCTGCCTGCGGCCAGATCGCATGACCTACGCTATCAAGAACTTCGTGGAGGAAAAGATGGGCAGCAAGTTCGTGGAAGGCC
GGAGTGTTGAGTTTTCTAAGTCCTACGAGGAGAGCAGCCCCTCCACGTCAATCTTCTTCATCCTCTCCCCGGGGGTTGACCCCTTGAAAG
ACGTGGAAGCCCTGGGAAAAAAACTAGGGTTTACCATAGACAATGGAAAACTCCATAATGTGTCCCTGGGGCAGGGACAAGAGGTGGTGG
CTGAGAACGCCCTGGACGTGGCTGCAGAGAAAGGACACTGGGTCATTCTGCAGAATATCCACCTGGTGGCCCGGTGGCTGGGAACACTGG
ACAAGAAGCTGGAGCACTACAGCACGGGCAGCCATGAGGACTACCGGGTGTTCATCAGCGCGGAGCCTGCCCCCAGCCCCGAGACCCACA
TCATCCCCCAGGGCATTCTGGAGAACGCCATCAAGATCACCAACGAGCCCCCCACGGGCATGCACGCCAACTTGCACAAGGCCCTGGACC
TGTTCACCCAGGACACCCTGGAGATGTGCACCAAGGAGATGGAGTTCAAGTGCATGCTCTTCGCCCTGTGCTACTTCCACGCTGTGGTGG
CAGAGAGGCGCAAGTTCGGCGCCCAGGGCTGGAACCGGTCGTACCCCTTCAACAACGGGGACCTCACCATCTCCATCAACGTGCTCTACA
ACTACCTGGAGGCCAACCCCAAGGTGCCCTGGGACGATCTCCGCTACCTTTTTGGTGAAATCATGTATGGCGGCCACATCACAGATGACT
GGGACCGTCGGCTGTGCAGGACCTACCTGGCTGAATACATCCGGACGGAGATGCTGGAGGGAGACGTCCTGCTGGCCCCCGGCTTTCAGA
TCCCCCCCAACCTGGACTACAAGGGTTACCACGAATACATCGATGAGAACCTGCCCCCTGAGAGTCCCTATCTGTATGGCCTGCACCCCA
ACGCAGAGATTGGCTTTCTGACGGTCACCTCAGAGAAGCTGTTCCGCACTGTCCTGGAAATGCAGCCAAAAGAGACGGACTCGGGGGCAG
GCACGGGAGTGTCCCGCGAGGAGAAGGTGAAGGCCGTGCTGGACGACATCCTGGAGAAGATTCCGGAGACTTTCAACATGGCTGAGATCA
TGGCAAAGGCAGCGGAAAAGACCCCCTACGTGGTAGTCGCCTTTCAAGAATGTGAAAGAATGAACATCCTGACCAACGAAATGCGCCGTT
CGCTCAAGGAGCTGAACCTGGGGCTGAAGGGAGAACTGACCATCACGACCGACGTGGAAGATCTGTCCACGGCTCTCTTCTATGACACCG
TGCCTGATACGTGGGTGGCCCGGGCCTACCCCTCCATGATGGGCCTGGCGGCCTGGTACGCAGACCTGCTGCTCCGCATCAGGGAACTCG
AGGCCTGGACGACAGACTTTGCCCTGCCCACCACCGTGTGGCTGGCCGGCTTCTTCAACCCCCAGTCGTTCCTCACGGCCATCATGCAGT
CCATGGCCAGGAAGAACGAGTGGCCCCTGGACAAGATGTGTCTGTCTGTCGAGGTGACCAAGAAAAACCGAGAGGACATGACCGCTCCTC
CGCGAGAGGGCTCCTACGTGTACGGACTCTTCATGGAAGGGGCTCGCTGGGACACCCAGACTGGAGTCATCGCTGAAGCGCGGCTGAAAG
AGCTGACCCCGGCCATGCCTGTCATCTTCATCAAGGCCATTCCTGTGGACCGCATGGAGACCAAGAACATCTATGAGTGTCCCGTGTACA
AAACACGCATCCGCGGCCCCACCTATGTCTGGACCTTTAACTTGAAGACCAAAGAGAAGGCAGCGAAGTGGATCCTGGCAGCCGTGGCGC
TGCTCCTACAGGTTTAGCTCGCTCCTGCCTCACAGCCCACACTCCCTGGGGCTGGACCACAACTCAGCCCTTCACCTGTGCACCTGTGAC
TTATTCTTTACAGGAACTGGTGGTGGTTTTTCGTTCTCTTAAATAATCAGGTGCTTTGTAACCAAGCACATCGGAACCAGAGGGTGGAGG

>94097_94097_2_TRIM37-DNAH17_TRIM37_chr17_57161363_ENST00000262294_DNAH17_chr17_76441762_ENST00000585328_length(amino acids)=887AA_BP=162
MTWAPGFYRRFDLATSGRRLRGQTAEPAGRQRPRREPEAMDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQC
PHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMVLSMKKELNPVELDFLLR
FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNF
VEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ
NIHLVARWLGTLDKKLEHYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKC
MLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEM
LEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDIL
EKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAA
WYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWD

--------------------------------------------------------------
>94097_94097_3_TRIM37-DNAH17_TRIM37_chr17_57161363_ENST00000393065_DNAH17_chr17_76441762_ENST00000389840_length(transcript)=3130nt_BP=632nt
GAATTCTCTGCGGCACCTTCTTCGCTGAACTCCACCGTCAGTTCCATAGGCGCGCGCCCGCGTCACGTGGGCCGAGGTTCCGGCGCGGCT
GCTGGCCGGCGGCTGAGCCGGGAGAAAGGAGCTGCGGCCACCGTTCGCCCTACTTCTGCGCCTCGGGGCGGGCGCGCCGGTAAAAATGGC
GAAATGGGGGTAGGCGGCGCTGGACCTGAAGAGATGGGGCGCGCAGGTGGGGCGGTTGTCAGAGCCCCCTGACGTGGGCGCCGGGCTTTT
ATCGGCGATTTGATCTGGCGACCTCGGGCCGGCGCCTAAGAGGTCAGACTGCGGAGCCTGCGGGTCGCCAGCGGCCCCGCCGAGAGCCGG
AGGCAATGGATGAACAGAGCGTGGAGCGCTGGCTGACAGAGCAGAGAGCTCAATGTCCTCATTGCCGTGCTCCACTCCAGCTACGAGAAC
TAGTAAATTGTCGTTGGGCAGAAGAAGTAACACAACAGCTTGATACTCTTCAACTCTGCAGTCTCACCAAACATGAAGAAAATGAAAAGG
ACAAATGTGAAAATCACCATGAAAAACTTAGTGTATTTTGCTGGACTTGTAAGAAGTGTATCTGCCATCAGTGTGCACTTTGGGGAGGAA
TGGTCCTGTCCATGAAGAAGGAGCTGAACCCAGTGGAGCTGGATTTCCTCCTGCGGTTCCCTTTTAAGGCCGGAGTGGTCTCACCAGTGG
ACTTCCTCCAGCATCAAGGCTGGGGCGGGATCAAGGCCCTCTCGGAGATGGATGAGTTCAAAAATCTGGACAGTGACATCGAAGGATCTG
CCAAGCGCTGGAAAAAGCTGGTGGAGTCGGAAGCCCCCGAGAAGGAGATCTTCCCCAAGGAGTGGAAGAACAAGACGGCCCTGCAGAAGC
TGTGCATGGTGCGCTGCCTGCGGCCAGATCGCATGACCTACGCTATCAAGAACTTCGTGGAGGAAAAGATGGGCAGCAAGTTCGTGGAAG
GCCGGAGTGTTGAGTTTTCTAAGTCCTACGAGGAGAGCAGCCCCTCCACGTCAATCTTCTTCATCCTCTCCCCGGGGGTTGACCCCTTGA
AAGACGTGGAAGCCCTGGGAAAAAAACTAGGGTTTACCATAGACAATGGAAAACTCCATAATGTGTCCCTGGGGCAGGGACAAGAGGTGG
TGGCTGAGAACGCCCTGGACGTGGCTGCAGAGAAAGGACACTGGGTCATTCTGCAGGTACGAGGGGGCCAGCACTGCAGGAATATCCACC
TGGTGGCCCGGTGGCTGGGAACACTGGACAAGAAGCTGGAGCACTACAGCACGGGCAGCCATGAGGACTACCGGGTGTTCATCAGCGCGG
AGCCTGCCCCCAGCCCCGAGACCCACATCATCCCCCAGGGCATTCTGGAGAACGCCATCAAGATCACCAACGAGCCCCCCACGGGCATGC
ACGCCAACTTGCACAAGGCCCTGGACCTGTTCACCCAGGACACCCTGGAGATGTGCACCAAGGAGATGGAGTTCAAGTGCATGCTCTTCG
CCCTGTGCTACTTCCACGCTGTGGTGGCAGAGAGGCGCAAGTTCGGCGCCCAGGGCTGGAACCGGTCGTACCCCTTCAACAACGGGGACC
TCACCATCTCCATCAACGTGCTCTACAACTACCTGGAGGCCAACCCCAAGGTGCCCTGGGACGATCTCCGCTACCTTTTTGGTGAAATCA
TGTATGGCGGCCACATCACAGATGACTGGGACCGTCGGCTGTGCAGGACCTACCTGGCTGAATACATCCGGACGGAGATGCTGGAGGGAG
ACGTCCTGCTGGCCCCCGGCTTTCAGATCCCCCCCAACCTGGACTACAAGGGTTACCACGAATACATCGATGAGAACCTGCCCCCTGAGA
GTCCCTATCTGTATGGCCTGCACCCCAACGCAGAGATTGGCTTTCTGACGGTCACCTCAGAGAAGCTGTTCCGCACTGTCCTGGAAATGC
AGCCAAAAGAGACGGACTCGGGGGCAGGCACGGGAGTGTCCCGCGAGGAGAAGGCAGGATCTTTGAAACTGCTCCCAAGCGAGAGGAAGG
GGGAGGATCTAGAACTGAGGAGGGGGGGCTGTCCGGGGACTGGCTTCCAGGTGAAGGCCGTGCTGGACGACATCCTGGAGAAGATTCCGG
AGACTTTCAACATGGCTGAGATCATGGCAAAGGCAGCGGAAAAGACCCCCTACGTGGTAGTCGCCTTTCAAGAATGTGAAAGAATGAACA
TCCTGACCAACGAAATGCGCCGTTCGCTCAAGGAGCTGAACCTGGGGCTGAAGGGAGAACTGACCATCACGACCGACGTGGAAGATCTGT
CCACGGCTCTCTTCTATGACACCGTGCCTGATACGTGGGTGGCCCGGGCCTACCCCTCCATGATGGGCCTGGCGGCCTGGTACGCAGACC
TGCTGCTCCGCATCAGGGAACTCGAGGCCTGGACGACAGACTTTGCCCTGCCCACCACCGTGTGGCTGGCCGGCTTCTTCAACCCCCAGT
CGTTCCTCACGGCCATCATGCAGTCCATGGCCAGGAAGAACGAGTGGCCCCTGGACAAGATGTGTCTGTCTGTCGAGGTGACCAAGAAAA
ACCGAGAGGACATGACCGCTCCTCCGCGAGAGGGCTCCTACGTGTACGGACTCTTCATGGAAGGGGCTCGCTGGGACACCCAGACTGGAG
TCATCGCTGAAGCGCGGCTGAAAGAGCTGACCCCGGCCATGCCTGTCATCTTCATCAAGGCCATTCCTGTGGACCGCATGGAGACCAAGA
ACATCTATGAGTGTCCCGTGTACAAAACACGCATCCGCGGCCCCACCTATGTCTGGACCTTTAACTTGAAGACCAAAGAGAAGGCAGCGA
AGTGGATCCTGGCAGCCGTGGCGCTGCTCCTACAGGTTTAGCTCGCTCCTGCCTCACAGCCCACACTCCCTGGGGCTGGACCACAACTCA
GCCCTTCACCTGTGCACCTGTGACTTATTCTTTACAGGAACTGGTGGTGGTTTTTCGTTCTCTTAAATAATCAGGTGCTTTGTAACCAAG

>94097_94097_3_TRIM37-DNAH17_TRIM37_chr17_57161363_ENST00000393065_DNAH17_chr17_76441762_ENST00000389840_length(amino acids)=890AA_BP=128
MTWAPGFYRRFDLATSGRRLRGQTAEPAGRQRPRREPEAMDEQSVERWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLT
KHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNL
DSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFIL
SPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLEHYSTGSHED
YRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRS
YPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYI
DENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLD
DILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMG
LAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGA

--------------------------------------------------------------
>94097_94097_4_TRIM37-DNAH17_TRIM37_chr17_57161363_ENST00000393065_DNAH17_chr17_76441762_ENST00000585328_length(transcript)=3019nt_BP=632nt
GAATTCTCTGCGGCACCTTCTTCGCTGAACTCCACCGTCAGTTCCATAGGCGCGCGCCCGCGTCACGTGGGCCGAGGTTCCGGCGCGGCT
GCTGGCCGGCGGCTGAGCCGGGAGAAAGGAGCTGCGGCCACCGTTCGCCCTACTTCTGCGCCTCGGGGCGGGCGCGCCGGTAAAAATGGC
GAAATGGGGGTAGGCGGCGCTGGACCTGAAGAGATGGGGCGCGCAGGTGGGGCGGTTGTCAGAGCCCCCTGACGTGGGCGCCGGGCTTTT
ATCGGCGATTTGATCTGGCGACCTCGGGCCGGCGCCTAAGAGGTCAGACTGCGGAGCCTGCGGGTCGCCAGCGGCCCCGCCGAGAGCCGG
AGGCAATGGATGAACAGAGCGTGGAGCGCTGGCTGACAGAGCAGAGAGCTCAATGTCCTCATTGCCGTGCTCCACTCCAGCTACGAGAAC
TAGTAAATTGTCGTTGGGCAGAAGAAGTAACACAACAGCTTGATACTCTTCAACTCTGCAGTCTCACCAAACATGAAGAAAATGAAAAGG
ACAAATGTGAAAATCACCATGAAAAACTTAGTGTATTTTGCTGGACTTGTAAGAAGTGTATCTGCCATCAGTGTGCACTTTGGGGAGGAA
TGGTCCTGTCCATGAAGAAGGAGCTGAACCCAGTGGAGCTGGATTTCCTCCTGCGGTTCCCTTTTAAGGCCGGAGTGGTCTCACCAGTGG
ACTTCCTCCAGCATCAAGGCTGGGGCGGGATCAAGGCCCTCTCGGAGATGGATGAGTTCAAAAATCTGGACAGTGACATCGAAGGATCTG
CCAAGCGCTGGAAAAAGCTGGTGGAGTCGGAAGCCCCCGAGAAGGAGATCTTCCCCAAGGAGTGGAAGAACAAGACGGCCCTGCAGAAGC
TGTGCATGGTGCGCTGCCTGCGGCCAGATCGCATGACCTACGCTATCAAGAACTTCGTGGAGGAAAAGATGGGCAGCAAGTTCGTGGAAG
GCCGGAGTGTTGAGTTTTCTAAGTCCTACGAGGAGAGCAGCCCCTCCACGTCAATCTTCTTCATCCTCTCCCCGGGGGTTGACCCCTTGA
AAGACGTGGAAGCCCTGGGAAAAAAACTAGGGTTTACCATAGACAATGGAAAACTCCATAATGTGTCCCTGGGGCAGGGACAAGAGGTGG
TGGCTGAGAACGCCCTGGACGTGGCTGCAGAGAAAGGACACTGGGTCATTCTGCAGAATATCCACCTGGTGGCCCGGTGGCTGGGAACAC
TGGACAAGAAGCTGGAGCACTACAGCACGGGCAGCCATGAGGACTACCGGGTGTTCATCAGCGCGGAGCCTGCCCCCAGCCCCGAGACCC
ACATCATCCCCCAGGGCATTCTGGAGAACGCCATCAAGATCACCAACGAGCCCCCCACGGGCATGCACGCCAACTTGCACAAGGCCCTGG
ACCTGTTCACCCAGGACACCCTGGAGATGTGCACCAAGGAGATGGAGTTCAAGTGCATGCTCTTCGCCCTGTGCTACTTCCACGCTGTGG
TGGCAGAGAGGCGCAAGTTCGGCGCCCAGGGCTGGAACCGGTCGTACCCCTTCAACAACGGGGACCTCACCATCTCCATCAACGTGCTCT
ACAACTACCTGGAGGCCAACCCCAAGGTGCCCTGGGACGATCTCCGCTACCTTTTTGGTGAAATCATGTATGGCGGCCACATCACAGATG
ACTGGGACCGTCGGCTGTGCAGGACCTACCTGGCTGAATACATCCGGACGGAGATGCTGGAGGGAGACGTCCTGCTGGCCCCCGGCTTTC
AGATCCCCCCCAACCTGGACTACAAGGGTTACCACGAATACATCGATGAGAACCTGCCCCCTGAGAGTCCCTATCTGTATGGCCTGCACC
CCAACGCAGAGATTGGCTTTCTGACGGTCACCTCAGAGAAGCTGTTCCGCACTGTCCTGGAAATGCAGCCAAAAGAGACGGACTCGGGGG
CAGGCACGGGAGTGTCCCGCGAGGAGAAGGTGAAGGCCGTGCTGGACGACATCCTGGAGAAGATTCCGGAGACTTTCAACATGGCTGAGA
TCATGGCAAAGGCAGCGGAAAAGACCCCCTACGTGGTAGTCGCCTTTCAAGAATGTGAAAGAATGAACATCCTGACCAACGAAATGCGCC
GTTCGCTCAAGGAGCTGAACCTGGGGCTGAAGGGAGAACTGACCATCACGACCGACGTGGAAGATCTGTCCACGGCTCTCTTCTATGACA
CCGTGCCTGATACGTGGGTGGCCCGGGCCTACCCCTCCATGATGGGCCTGGCGGCCTGGTACGCAGACCTGCTGCTCCGCATCAGGGAAC
TCGAGGCCTGGACGACAGACTTTGCCCTGCCCACCACCGTGTGGCTGGCCGGCTTCTTCAACCCCCAGTCGTTCCTCACGGCCATCATGC
AGTCCATGGCCAGGAAGAACGAGTGGCCCCTGGACAAGATGTGTCTGTCTGTCGAGGTGACCAAGAAAAACCGAGAGGACATGACCGCTC
CTCCGCGAGAGGGCTCCTACGTGTACGGACTCTTCATGGAAGGGGCTCGCTGGGACACCCAGACTGGAGTCATCGCTGAAGCGCGGCTGA
AAGAGCTGACCCCGGCCATGCCTGTCATCTTCATCAAGGCCATTCCTGTGGACCGCATGGAGACCAAGAACATCTATGAGTGTCCCGTGT
ACAAAACACGCATCCGCGGCCCCACCTATGTCTGGACCTTTAACTTGAAGACCAAAGAGAAGGCAGCGAAGTGGATCCTGGCAGCCGTGG
CGCTGCTCCTACAGGTTTAGCTCGCTCCTGCCTCACAGCCCACACTCCCTGGGGCTGGACCACAACTCAGCCCTTCACCTGTGCACCTGT
GACTTATTCTTTACAGGAACTGGTGGTGGTTTTTCGTTCTCTTAAATAATCAGGTGCTTTGTAACCAAGCACATCGGAACCAGAGGGTGG

>94097_94097_4_TRIM37-DNAH17_TRIM37_chr17_57161363_ENST00000393065_DNAH17_chr17_76441762_ENST00000585328_length(amino acids)=853AA_BP=128
MTWAPGFYRRFDLATSGRRLRGQTAEPAGRQRPRREPEAMDEQSVERWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLT
KHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNL
DSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFIL
SPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLGTLDKKLEHYSTGSHEDYRVFISAE
PAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDL
TISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPES
PYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMN
ILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQ
SFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETK

--------------------------------------------------------------
>94097_94097_5_TRIM37-DNAH17_TRIM37_chr17_57161363_ENST00000393066_DNAH17_chr17_76441762_ENST00000389840_length(transcript)=3327nt_BP=829nt
CCTCCTTTCCCCTCCCACAGCGTCCTGCGCGCATGCGCTTCGCAGCTTCTCTCGCCGCCGCGCCCCCAGCTGCTCTGGTTACGGTTGGTG
TTTGCGAATTCTCTGCGGCACCTTCTTCGCTGAACTCCACCGTCAGTTCCATAGGCGCGCGCCCGCGTCACGTGGGCCGAGGTTCCGGCG
CGGCTGCTGGCCGGCGGCTGAGCCGGGAGAAAGGAGCTGCGGCCACCGTTCGCCCTACTTCTGCGCCTCGGGGCGGGCGCGCCGGTAAAA
ATGGCGAAATGGGGGTAGGCGGCGCTGGACCTGAAGAGATGGGGCGCGCAGGTGGGGCGGTTGTCAGAGCCCCCTGACGTGGGCGCCGGG
CTTTTATCGGCGATTTGATCTGGCGACCTCGGGCCGGCGCCTAAGAGGTCAGACTGCGGAGCCTGCGGGTCGCCAGCGGCCCCGCCGAGA
GCCGGAGGCAATGGATGAACAGAGCGTGGAGAGCATTGCTGAGGTTTTCCGATGTTTCATTTGTATGGAGAAATTGCGGGATGCACGCCT
GTGTCCTCATTGCTCCAAACTGTGTTGTTTCAGCTGTATTAGGCGCTGGCTGACAGAGCAGAGAGCTCAATGTCCTCATTGCCGTGCTCC
ACTCCAGCTACGAGAACTAGTAAATTGTCGTTGGGCAGAAGAAGTAACACAACAGCTTGATACTCTTCAACTCTGCAGTCTCACCAAACA
TGAAGAAAATGAAAAGGACAAATGTGAAAATCACCATGAAAAACTTAGTGTATTTTGCTGGACTTGTAAGAAGTGTATCTGCCATCAGTG
TGCACTTTGGGGAGGAATGGTCCTGTCCATGAAGAAGGAGCTGAACCCAGTGGAGCTGGATTTCCTCCTGCGGTTCCCTTTTAAGGCCGG
AGTGGTCTCACCAGTGGACTTCCTCCAGCATCAAGGCTGGGGCGGGATCAAGGCCCTCTCGGAGATGGATGAGTTCAAAAATCTGGACAG
TGACATCGAAGGATCTGCCAAGCGCTGGAAAAAGCTGGTGGAGTCGGAAGCCCCCGAGAAGGAGATCTTCCCCAAGGAGTGGAAGAACAA
GACGGCCCTGCAGAAGCTGTGCATGGTGCGCTGCCTGCGGCCAGATCGCATGACCTACGCTATCAAGAACTTCGTGGAGGAAAAGATGGG
CAGCAAGTTCGTGGAAGGCCGGAGTGTTGAGTTTTCTAAGTCCTACGAGGAGAGCAGCCCCTCCACGTCAATCTTCTTCATCCTCTCCCC
GGGGGTTGACCCCTTGAAAGACGTGGAAGCCCTGGGAAAAAAACTAGGGTTTACCATAGACAATGGAAAACTCCATAATGTGTCCCTGGG
GCAGGGACAAGAGGTGGTGGCTGAGAACGCCCTGGACGTGGCTGCAGAGAAAGGACACTGGGTCATTCTGCAGGTACGAGGGGGCCAGCA
CTGCAGGAATATCCACCTGGTGGCCCGGTGGCTGGGAACACTGGACAAGAAGCTGGAGCACTACAGCACGGGCAGCCATGAGGACTACCG
GGTGTTCATCAGCGCGGAGCCTGCCCCCAGCCCCGAGACCCACATCATCCCCCAGGGCATTCTGGAGAACGCCATCAAGATCACCAACGA
GCCCCCCACGGGCATGCACGCCAACTTGCACAAGGCCCTGGACCTGTTCACCCAGGACACCCTGGAGATGTGCACCAAGGAGATGGAGTT
CAAGTGCATGCTCTTCGCCCTGTGCTACTTCCACGCTGTGGTGGCAGAGAGGCGCAAGTTCGGCGCCCAGGGCTGGAACCGGTCGTACCC
CTTCAACAACGGGGACCTCACCATCTCCATCAACGTGCTCTACAACTACCTGGAGGCCAACCCCAAGGTGCCCTGGGACGATCTCCGCTA
CCTTTTTGGTGAAATCATGTATGGCGGCCACATCACAGATGACTGGGACCGTCGGCTGTGCAGGACCTACCTGGCTGAATACATCCGGAC
GGAGATGCTGGAGGGAGACGTCCTGCTGGCCCCCGGCTTTCAGATCCCCCCCAACCTGGACTACAAGGGTTACCACGAATACATCGATGA
GAACCTGCCCCCTGAGAGTCCCTATCTGTATGGCCTGCACCCCAACGCAGAGATTGGCTTTCTGACGGTCACCTCAGAGAAGCTGTTCCG
CACTGTCCTGGAAATGCAGCCAAAAGAGACGGACTCGGGGGCAGGCACGGGAGTGTCCCGCGAGGAGAAGGCAGGATCTTTGAAACTGCT
CCCAAGCGAGAGGAAGGGGGAGGATCTAGAACTGAGGAGGGGGGGCTGTCCGGGGACTGGCTTCCAGGTGAAGGCCGTGCTGGACGACAT
CCTGGAGAAGATTCCGGAGACTTTCAACATGGCTGAGATCATGGCAAAGGCAGCGGAAAAGACCCCCTACGTGGTAGTCGCCTTTCAAGA
ATGTGAAAGAATGAACATCCTGACCAACGAAATGCGCCGTTCGCTCAAGGAGCTGAACCTGGGGCTGAAGGGAGAACTGACCATCACGAC
CGACGTGGAAGATCTGTCCACGGCTCTCTTCTATGACACCGTGCCTGATACGTGGGTGGCCCGGGCCTACCCCTCCATGATGGGCCTGGC
GGCCTGGTACGCAGACCTGCTGCTCCGCATCAGGGAACTCGAGGCCTGGACGACAGACTTTGCCCTGCCCACCACCGTGTGGCTGGCCGG
CTTCTTCAACCCCCAGTCGTTCCTCACGGCCATCATGCAGTCCATGGCCAGGAAGAACGAGTGGCCCCTGGACAAGATGTGTCTGTCTGT
CGAGGTGACCAAGAAAAACCGAGAGGACATGACCGCTCCTCCGCGAGAGGGCTCCTACGTGTACGGACTCTTCATGGAAGGGGCTCGCTG
GGACACCCAGACTGGAGTCATCGCTGAAGCGCGGCTGAAAGAGCTGACCCCGGCCATGCCTGTCATCTTCATCAAGGCCATTCCTGTGGA
CCGCATGGAGACCAAGAACATCTATGAGTGTCCCGTGTACAAAACACGCATCCGCGGCCCCACCTATGTCTGGACCTTTAACTTGAAGAC
CAAAGAGAAGGCAGCGAAGTGGATCCTGGCAGCCGTGGCGCTGCTCCTACAGGTTTAGCTCGCTCCTGCCTCACAGCCCACACTCCCTGG
GGCTGGACCACAACTCAGCCCTTCACCTGTGCACCTGTGACTTATTCTTTACAGGAACTGGTGGTGGTTTTTCGTTCTCTTAAATAATCA

>94097_94097_5_TRIM37-DNAH17_TRIM37_chr17_57161363_ENST00000393066_DNAH17_chr17_76441762_ENST00000389840_length(amino acids)=924AA_BP=162
MTWAPGFYRRFDLATSGRRLRGQTAEPAGRQRPRREPEAMDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQC
PHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMVLSMKKELNPVELDFLLR
FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNF
VEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ
VRGGQHCRNIHLVARWLGTLDKKLEHYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMC
TKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYL
AEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKA
GSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKG
ELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLD
KMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVW

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>94097_94097_6_TRIM37-DNAH17_TRIM37_chr17_57161363_ENST00000393066_DNAH17_chr17_76441762_ENST00000585328_length(transcript)=3216nt_BP=829nt
CCTCCTTTCCCCTCCCACAGCGTCCTGCGCGCATGCGCTTCGCAGCTTCTCTCGCCGCCGCGCCCCCAGCTGCTCTGGTTACGGTTGGTG
TTTGCGAATTCTCTGCGGCACCTTCTTCGCTGAACTCCACCGTCAGTTCCATAGGCGCGCGCCCGCGTCACGTGGGCCGAGGTTCCGGCG
CGGCTGCTGGCCGGCGGCTGAGCCGGGAGAAAGGAGCTGCGGCCACCGTTCGCCCTACTTCTGCGCCTCGGGGCGGGCGCGCCGGTAAAA
ATGGCGAAATGGGGGTAGGCGGCGCTGGACCTGAAGAGATGGGGCGCGCAGGTGGGGCGGTTGTCAGAGCCCCCTGACGTGGGCGCCGGG
CTTTTATCGGCGATTTGATCTGGCGACCTCGGGCCGGCGCCTAAGAGGTCAGACTGCGGAGCCTGCGGGTCGCCAGCGGCCCCGCCGAGA
GCCGGAGGCAATGGATGAACAGAGCGTGGAGAGCATTGCTGAGGTTTTCCGATGTTTCATTTGTATGGAGAAATTGCGGGATGCACGCCT
GTGTCCTCATTGCTCCAAACTGTGTTGTTTCAGCTGTATTAGGCGCTGGCTGACAGAGCAGAGAGCTCAATGTCCTCATTGCCGTGCTCC
ACTCCAGCTACGAGAACTAGTAAATTGTCGTTGGGCAGAAGAAGTAACACAACAGCTTGATACTCTTCAACTCTGCAGTCTCACCAAACA
TGAAGAAAATGAAAAGGACAAATGTGAAAATCACCATGAAAAACTTAGTGTATTTTGCTGGACTTGTAAGAAGTGTATCTGCCATCAGTG
TGCACTTTGGGGAGGAATGGTCCTGTCCATGAAGAAGGAGCTGAACCCAGTGGAGCTGGATTTCCTCCTGCGGTTCCCTTTTAAGGCCGG
AGTGGTCTCACCAGTGGACTTCCTCCAGCATCAAGGCTGGGGCGGGATCAAGGCCCTCTCGGAGATGGATGAGTTCAAAAATCTGGACAG
TGACATCGAAGGATCTGCCAAGCGCTGGAAAAAGCTGGTGGAGTCGGAAGCCCCCGAGAAGGAGATCTTCCCCAAGGAGTGGAAGAACAA
GACGGCCCTGCAGAAGCTGTGCATGGTGCGCTGCCTGCGGCCAGATCGCATGACCTACGCTATCAAGAACTTCGTGGAGGAAAAGATGGG
CAGCAAGTTCGTGGAAGGCCGGAGTGTTGAGTTTTCTAAGTCCTACGAGGAGAGCAGCCCCTCCACGTCAATCTTCTTCATCCTCTCCCC
GGGGGTTGACCCCTTGAAAGACGTGGAAGCCCTGGGAAAAAAACTAGGGTTTACCATAGACAATGGAAAACTCCATAATGTGTCCCTGGG
GCAGGGACAAGAGGTGGTGGCTGAGAACGCCCTGGACGTGGCTGCAGAGAAAGGACACTGGGTCATTCTGCAGAATATCCACCTGGTGGC
CCGGTGGCTGGGAACACTGGACAAGAAGCTGGAGCACTACAGCACGGGCAGCCATGAGGACTACCGGGTGTTCATCAGCGCGGAGCCTGC
CCCCAGCCCCGAGACCCACATCATCCCCCAGGGCATTCTGGAGAACGCCATCAAGATCACCAACGAGCCCCCCACGGGCATGCACGCCAA
CTTGCACAAGGCCCTGGACCTGTTCACCCAGGACACCCTGGAGATGTGCACCAAGGAGATGGAGTTCAAGTGCATGCTCTTCGCCCTGTG
CTACTTCCACGCTGTGGTGGCAGAGAGGCGCAAGTTCGGCGCCCAGGGCTGGAACCGGTCGTACCCCTTCAACAACGGGGACCTCACCAT
CTCCATCAACGTGCTCTACAACTACCTGGAGGCCAACCCCAAGGTGCCCTGGGACGATCTCCGCTACCTTTTTGGTGAAATCATGTATGG
CGGCCACATCACAGATGACTGGGACCGTCGGCTGTGCAGGACCTACCTGGCTGAATACATCCGGACGGAGATGCTGGAGGGAGACGTCCT
GCTGGCCCCCGGCTTTCAGATCCCCCCCAACCTGGACTACAAGGGTTACCACGAATACATCGATGAGAACCTGCCCCCTGAGAGTCCCTA
TCTGTATGGCCTGCACCCCAACGCAGAGATTGGCTTTCTGACGGTCACCTCAGAGAAGCTGTTCCGCACTGTCCTGGAAATGCAGCCAAA
AGAGACGGACTCGGGGGCAGGCACGGGAGTGTCCCGCGAGGAGAAGGTGAAGGCCGTGCTGGACGACATCCTGGAGAAGATTCCGGAGAC
TTTCAACATGGCTGAGATCATGGCAAAGGCAGCGGAAAAGACCCCCTACGTGGTAGTCGCCTTTCAAGAATGTGAAAGAATGAACATCCT
GACCAACGAAATGCGCCGTTCGCTCAAGGAGCTGAACCTGGGGCTGAAGGGAGAACTGACCATCACGACCGACGTGGAAGATCTGTCCAC
GGCTCTCTTCTATGACACCGTGCCTGATACGTGGGTGGCCCGGGCCTACCCCTCCATGATGGGCCTGGCGGCCTGGTACGCAGACCTGCT
GCTCCGCATCAGGGAACTCGAGGCCTGGACGACAGACTTTGCCCTGCCCACCACCGTGTGGCTGGCCGGCTTCTTCAACCCCCAGTCGTT
CCTCACGGCCATCATGCAGTCCATGGCCAGGAAGAACGAGTGGCCCCTGGACAAGATGTGTCTGTCTGTCGAGGTGACCAAGAAAAACCG
AGAGGACATGACCGCTCCTCCGCGAGAGGGCTCCTACGTGTACGGACTCTTCATGGAAGGGGCTCGCTGGGACACCCAGACTGGAGTCAT
CGCTGAAGCGCGGCTGAAAGAGCTGACCCCGGCCATGCCTGTCATCTTCATCAAGGCCATTCCTGTGGACCGCATGGAGACCAAGAACAT
CTATGAGTGTCCCGTGTACAAAACACGCATCCGCGGCCCCACCTATGTCTGGACCTTTAACTTGAAGACCAAAGAGAAGGCAGCGAAGTG
GATCCTGGCAGCCGTGGCGCTGCTCCTACAGGTTTAGCTCGCTCCTGCCTCACAGCCCACACTCCCTGGGGCTGGACCACAACTCAGCCC
TTCACCTGTGCACCTGTGACTTATTCTTTACAGGAACTGGTGGTGGTTTTTCGTTCTCTTAAATAATCAGGTGCTTTGTAACCAAGCACA

>94097_94097_6_TRIM37-DNAH17_TRIM37_chr17_57161363_ENST00000393066_DNAH17_chr17_76441762_ENST00000585328_length(amino acids)=887AA_BP=162
MTWAPGFYRRFDLATSGRRLRGQTAEPAGRQRPRREPEAMDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQC
PHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMVLSMKKELNPVELDFLLR
FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNF
VEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ
NIHLVARWLGTLDKKLEHYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKC
MLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEM
LEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDIL
EKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAA
WYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWD

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Fusion Gene PPI Analysis for TRIM37-DNAH17


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TRIM37-DNAH17


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TRIM37-DNAH17


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource