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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TRIO-DNAH5 (FusionGDB2 ID:94199)

Fusion Gene Summary for TRIO-DNAH5

check button Fusion gene summary
Fusion gene informationFusion gene name: TRIO-DNAH5
Fusion gene ID: 94199
HgeneTgene
Gene symbol

TRIO

DNAH5

Gene ID

7204

1767

Gene nametrio Rho guanine nucleotide exchange factordynein axonemal heavy chain 5
SynonymsARHGEF23|MEBAS|MRD44|tgatCILD3|DNAHC5|HL1|KTGNR|PCD
Cytomap

5p15.2

5p15.2

Type of geneprotein-codingprotein-coding
Descriptiontriple functional domain proteinPTPRF-interacting proteintriple functional domain (PTPRF interacting)dynein heavy chain 5, axonemalaxonemal beta dynein heavy chain 5ciliary dynein heavy chain 5dynein, axonemal, heavy polypeptide 5
Modification date2020031320200327
UniProtAcc

TRIOBP

Q8TE73

Ensembl transtripts involved in fusion geneENST00000344204, ENST00000509967, 
ENST00000537187, ENST00000344135, 
ENST00000515710, 		ENST00000504001, 
ENST00000265104, 
Fusion gene scores* DoF score34 X 28 X 12=114249 X 7 X 6=378
# samples 358
** MAII scorelog2(35/11424*10)=-5.02856915219677
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/378*10)=-2.24031432933371
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TRIO [Title/Abstract] AND DNAH5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTRIO(14391099)-DNAH5(13931353), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across TRIO (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DNAH5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-55-7283-01ATRIOchr5

14391099

-DNAH5chr5

13931353

-
ChimerDB4LUADTCGA-55-7283-01ATRIOchr5

14391099

+DNAH5chr5

13931353

-


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Fusion Gene ORF analysis for TRIO-DNAH5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000344204ENST00000504001TRIOchr5

14391099

+DNAH5chr5

13931353

-
5CDS-intronENST00000509967ENST00000504001TRIOchr5

14391099

+DNAH5chr5

13931353

-
5CDS-intronENST00000537187ENST00000504001TRIOchr5

14391099

+DNAH5chr5

13931353

-
In-frameENST00000344204ENST00000265104TRIOchr5

14391099

+DNAH5chr5

13931353

-
In-frameENST00000509967ENST00000265104TRIOchr5

14391099

+DNAH5chr5

13931353

-
In-frameENST00000537187ENST00000265104TRIOchr5

14391099

+DNAH5chr5

13931353

-
intron-3CDSENST00000344135ENST00000265104TRIOchr5

14391099

+DNAH5chr5

13931353

-
intron-3CDSENST00000515710ENST00000265104TRIOchr5

14391099

+DNAH5chr5

13931353

-
intron-intronENST00000344135ENST00000504001TRIOchr5

14391099

+DNAH5chr5

13931353

-
intron-intronENST00000515710ENST00000504001TRIOchr5

14391099

+DNAH5chr5

13931353

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000344204TRIOchr514391099+ENST00000265104DNAH5chr513931353-19713424224180596011
ENST00000537187TRIOchr514391099+ENST00000265104DNAH5chr513931353-1969542246180416011
ENST00000509967TRIOchr514391099+ENST00000265104DNAH5chr513931353-196944223152180405962

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000344204ENST00000265104TRIOchr514391099+DNAH5chr513931353-0.0005435310.99945647
ENST00000537187ENST00000265104TRIOchr514391099+DNAH5chr513931353-0.0005324920.99946755
ENST00000509967ENST00000265104TRIOchr514391099+DNAH5chr513931353-0.000547080.9994529

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Fusion Genomic Features for TRIO-DNAH5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TRIO-DNAH5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:14391099/chr5:13931353)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
TRIO

TRIOBP

DNAH5

Q8TE73

2365FUNCTION: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+2757715_71814063098.0Compositional biasNote=Poly-Gln
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+2758715_71814062922.0Compositional biasNote=Poly-Gln
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+275765_21014063098.0DomainCRAL-TRIO
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+275865_21014062922.0DomainCRAL-TRIO
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+27571109_121614063098.0RepeatNote=Spectrin 4
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+2757311_41814063098.0RepeatNote=Spectrin 1
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+2757538_64414063098.0RepeatNote=Spectrin 2
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+2757878_98414063098.0RepeatNote=Spectrin 3
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+27581109_121614062922.0RepeatNote=Spectrin 4
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+2758311_41814062922.0RepeatNote=Spectrin 1
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+2758538_64414062922.0RepeatNote=Spectrin 2
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+2758878_98414062922.0RepeatNote=Spectrin 3
TgeneDNAH5chr5:14391099chr5:13931353ENST000002651040791435_1465194625.0Coiled coilOntology_term=ECO:0000255
TgeneDNAH5chr5:14391099chr5:13931353ENST00000265104079284_305194625.0Coiled coilOntology_term=ECO:0000255
TgeneDNAH5chr5:14391099chr5:13931353ENST000002651040793195_3302194625.0Coiled coilOntology_term=ECO:0000255
TgeneDNAH5chr5:14391099chr5:13931353ENST000002651040793426_3491194625.0Coiled coilOntology_term=ECO:0000255
TgeneDNAH5chr5:14391099chr5:13931353ENST000002651040793732_3817194625.0Coiled coilOntology_term=ECO:0000255
TgeneDNAH5chr5:14391099chr5:13931353ENST000002651040794392_4420194625.0Coiled coilOntology_term=ECO:0000255
TgeneDNAH5chr5:14391099chr5:13931353ENST00000265104079740_825194625.0Coiled coilOntology_term=ECO:0000255
TgeneDNAH5chr5:14391099chr5:13931353ENST000002651040791980_1987194625.0Nucleotide bindingATP
TgeneDNAH5chr5:14391099chr5:13931353ENST000002651040792262_2269194625.0Nucleotide bindingATP
TgeneDNAH5chr5:14391099chr5:13931353ENST000002651040791942_2164194625.0RegionAAA 1
TgeneDNAH5chr5:14391099chr5:13931353ENST000002651040792224_2443194625.0RegionAAA 2
TgeneDNAH5chr5:14391099chr5:13931353ENST000002651040792550_2803194625.0RegionAAA 3
TgeneDNAH5chr5:14391099chr5:13931353ENST000002651040792916_3170194625.0RegionAAA 4
TgeneDNAH5chr5:14391099chr5:13931353ENST000002651040793185_3482194625.0RegionStalk
TgeneDNAH5chr5:14391099chr5:13931353ENST000002651040793567_3797194625.0RegionAAA 5
TgeneDNAH5chr5:14391099chr5:13931353ENST000002651040794012_4226194625.0RegionAAA 6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+1101845_18500597.0Compositional biasNote=Poly-Ser
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+1102292_23120597.0Compositional biasNote=Poly-Gly
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+1102545_25510597.0Compositional biasNote=Poly-Ser
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+110715_7180597.0Compositional biasNote=Poly-Gln
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+27571845_185014063098.0Compositional biasNote=Poly-Ser
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+27572292_231214063098.0Compositional biasNote=Poly-Gly
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+27572545_255114063098.0Compositional biasNote=Poly-Ser
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+27581845_185014062922.0Compositional biasNote=Poly-Ser
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+27582292_231214062922.0Compositional biasNote=Poly-Gly
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+27582545_255114062922.0Compositional biasNote=Poly-Ser
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+1101292_14670597.0DomainDH 1
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+1101480_15910597.0DomainPH 1
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+1101656_17210597.0DomainSH3 1
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+1101969_21450597.0DomainDH 2
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+1102157_22710597.0DomainPH 2
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+1102551_26160597.0DomainSH3 2
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+1102685_27750597.0DomainNote=Ig-like C2-type
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+1102796_30520597.0DomainProtein kinase
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+11065_2100597.0DomainCRAL-TRIO
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+27571292_146714063098.0DomainDH 1
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+27571480_159114063098.0DomainPH 1
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+27571656_172114063098.0DomainSH3 1
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+27571969_214514063098.0DomainDH 2
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+27572157_227114063098.0DomainPH 2
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+27572551_261614063098.0DomainSH3 2
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+27572685_277514063098.0DomainNote=Ig-like C2-type
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+27572796_305214063098.0DomainProtein kinase
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+27581292_146714062922.0DomainDH 1
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+27581480_159114062922.0DomainPH 1
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+27581656_172114062922.0DomainSH3 1
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+27581969_214514062922.0DomainDH 2
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+27582157_227114062922.0DomainPH 2
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+27582551_261614062922.0DomainSH3 2
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+27582685_277514062922.0DomainNote=Ig-like C2-type
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+27582796_305214062922.0DomainProtein kinase
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+1102802_28100597.0Nucleotide bindingATP
HgeneTRIOchr5:14391099chr5:13931353ENST00000344204+27572802_281014063098.0Nucleotide bindingATP
HgeneTRIOchr5:14391099chr5:13931353ENST00000537187+27582802_281014062922.0Nucleotide bindingATP
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+1101109_12160597.0RepeatNote=Spectrin 4
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+110311_4180597.0RepeatNote=Spectrin 1
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+110538_6440597.0RepeatNote=Spectrin 2
HgeneTRIOchr5:14391099chr5:13931353ENST00000344135+110878_9840597.0RepeatNote=Spectrin 3
TgeneDNAH5chr5:14391099chr5:13931353ENST000002651040791_1941194625.0RegionStem


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Fusion Gene Sequence for TRIO-DNAH5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>94199_94199_1_TRIO-DNAH5_TRIO_chr5_14391099_ENST00000344204_DNAH5_chr5_13931353_ENST00000265104_length(transcript)=19713nt_BP=4242nt
GCGGCCGCGGGCGCCGCCGCAGCCATGAGCGGCAGCAGCGGCGGAGCCGCCGCCCCCGCCGCGTCCTCCGGCCCCGCCGCGGCGGCCAGC
GCGGCTGGCTCGGGCTGCGGGGGCGGTGCCGGCGAGGGGGCAGAGGAGGCGGCCAAGGACCTGGCCGACATCGCGGCCTTCTTCCGATCC
GGGTTTCGAAAAAACGATGAAATGAAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGGAGAGATAAA
CGTGGAGGTCCCATTTTAACGTTTCCGGCCCGCAGCAATCATGACAGAATACGACAGGAGGATCTCAGGAGACTCATTTCCTATCTAGCC
TGTATTCCCAGCGAGGAGGTCTGCAAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAGCCCCTTCTG
AAGATCCTGCAGGAGTCCTTCCCCTGCTGCATCCATGTGGCCCTGATCATCAAGCCAGACAACTTCTGGCAGAAACAGAGGACTAATTTT
GGCAGTTCTAAATTTGAATTTGAGACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACTCCTGAGTTT
GATGGCTGCCTGGAATACAACCACGAAGAATGGATTGAAATCAGAGTTGCTTTTGAAGACTACATTAGCAATGCCACCCACATGCTGTCT
CGGCTGGAGGAACTTCAGGACATCCTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAACATTCTCAG
CTGAAGAAGAAGGTGATTAAGGCCCCCATCGAGGACCTGGATTTGGAGGGACAGAAGCTGCTTCAGAGGATACAGAGCAGTGAAAGCTTT
CCCAAAAAGAACTCAGGCTCAGGCAATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCACTCGACACGG
CAGCATCTGCACCAGATGTGGCATGTGAGGAAGCTGAAGCTGGACCAGTGCTTCCAGCTGAGGCTGTTTGAACAGGATGCTGAGAAGATG
TTTGACTGGATCACACACAACAAAGGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAGCTTCAGACG
CAGCACAATCACTTTGCCATGAACTGTATGAACGTGTATGTAAATATAAACCGCATCATGTCGGTGGCCAATCGTCTGGTGGAGTCTGGC
CACTATGCCTCGCAGCAGATCAGGCAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAGCGGAGCACC
TTGCTGGACATGTCCTCCATTTTCCACCAGAAGGCCGAAAAGTATATGAGCAACGTGGATTCATGGTGTAAAGCTTGCGGTGAGGTAGAC
CTTCCCTCAGAGCTGCAGGACCTAGAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCTGAGGTCAGC
CAAGATGGGAAGTCGCTCCTTGACAAGCTCCAGCGGCCCTTGACTCCCGGCAGCTCCGATTCCCTGACAGCCTCTGCCAACTACTCCAAG
GCCGTGCACCATGTCCTGGATGTCATCCACGAGGTGCTGCACCACCAGCGGCAGCTGGAGAACATCTGGCAACACCGCAAGGTCCGGCTG
CATCAGAGGCTGCAGCTGTGTGTTTTCCAGCAGGACGTTCAGCAGGTGCTAGACTGGATCGAGAACCACGGAGAAGCATTTCTGAGCAAA
CATACAGGTGTGGGGAAATCTCTTCATCGGGCCAGAGCATTGCAGAAACGTCATGAAGATTTTGAAGAAGTGGCACAGAACACATACACC
AATGCGGATAAATTACTGGAAGCAGCAGAACAGCTGGCTCAGACTGGGGAATGTGACCCCGAAGAGATTTATCAGGCTGCCCATCAGCTG
GAAGACCGGATTCAAGATTTCGTTCGGCGTGTTGAGCAGCGAAAGATCCTACTGGACATGTCAGTGTCCTTTCACACCCATGTGAAAGAG
CTGTGGACGTGGCTGGAGGAGCTGCAGAAGGAGCTGCTGGACGACGTGTATGCCGAGTCGGTGGAGGCCGTGCAGGACCTCATCAAGCGC
TTTGGCCAGCAGCAGCAGACCACCCTGCAGGTGACTGTCAACGTGATCAAGGAAGGGGAGGACCTCATCCAGCAGCTCAGGGACTCTGCC
ATCTCCAGTAACAAGACCCCCCACAACAGCTCCATCAACCACATTGAGACGGTGCTGCAGCAGCTGGACGAGGCGCAGTCGCAGATGGAG
GAGCTCTTCCAGGAGCGCAAGATCAAGCTGGAGCTCTTCCTGCAGCTGCGCATCTTCGAGAGGGACGCCATCGACATTATCTCAGACCTC
GAGTCTTGGAATGATGAGCTTTCTCAGCAAATGAATGACTTCGACACAGAAGATCTCACGATTGCAGAGCAGCGCCTCCAGCACCATGCA
GACAAAGCCTTGACCATGAACAACTTGACTTTTGACGTCATCCACCAAGGGCAAGATCTTCTGCAGTATGTCAATGAGGTCCAGGCCTCT
GGTGTGGAGCTGCTGTGTGATAGAGATGTAGACATGGCAACTCGGGTCCAGGACCTGCTGGAGTTTCTTCATGAAAAACAGCAGGAATTG
GATTTAGCCGCAGAGCAGCATCGGAAACACCTGGAGCAGTGCGTGCAGCTGCGCCACCTGCAGGCAGAAGTGAAACAGGTGCTGGGTTGG
ATCCGCAACGGAGAGTCCATGTTAAATGCCGGACTTATCACAGCCAGCTCGTTACAAGAGGCAGAGCAGCTCCAGCGAGAGCACGAGCAG
TTCCAGCATGCCATTGAGAAAACACATCAGAGCGCGCTGCAGGTGCAGCAGAAGGCAGAAGCCATGCTACAGGCCAACCACTACGACATG
GACATGATCCGGGACTGCGCCGAGAAGGTGGCGTCTCACTGGCAACAGCTCATGCTCAAGATGGAAGATCGCCTCAAGCTCGTCAACGCC
TCTGTCGCTTTCTACAAAACCTCAGAGCAGGTCTGCAGCGTCCTCGAGAGCCTGGAACAGGAGTACAAGAGAGAAGAAGACTGGTGTGGC
GGGGCGGATAAGCTGGGCCCAAACTCTGAGACGGACCACGTGACGCCCATGATCAGCAAGCACCTGGAGCAGAAGGAGGCATTCCTGAAG
GCTTGCACCCTTGCTCGGAGGAATGCAGACGTCTTCCTGAAATACCTGCACAGGAACAGCGTGAACATGCCAGGAATGGTGACGCACATC
AAAGCTCCTGAACAGCAAGTGAAAAATATCTTGAATGAACTCTTCCAACGGGAGAACAGGGTATTGCATTACTGGACCATGAGGAAGAGA
CGGCTGGACCAGTGTCAGCAGTACGTGGTCTTTGAGAGGAGTGCCAAGCAGGCTTTGGAATGGATCCATGACAATGGCGAGTTCTACCTT
TCCACACACACCTCCACGGGCTCCAGTATACAGCACACCCAGGAGCTCCTGAAAGAGCACGAGGAGTTCCAGATAACTGCAAAGCAAACC
AAAGAGAGAGTGAAGCTATTGATACAGCTGGCTGATGGCTTTTGTGAAAAAGGGCATGCCCATGCGGCAGAGATAAAAAAATGTGTTACT
GCTGTGGATAAGAGGTACAGAGATTTCTCTCTGCGGATGGAGAAGTACAGGACCTCTTTGGAAAAAGCCCTGGGGATTTCTTCAGATTCC
AACAAATCGAGTAAAAGTCTCCAGCTAGATATCATTCCAGCCAGTATCCCTGGCTCAGAGGTGAAACTTCGAGATGCTGCTCATGAACTT
AATGAAGAGAAGCGGAAATCTGCCCGCAGGAAAGAGTTCATAATGGCTGAGCTCATTCAAACTGAAAAGGCTTATGTAAGAGACCTCCGG
GAATGTATGGATACGTACCTGTGGGAAATGACCAGTGGCGTGGAAGAGATTCCACCTGGCATTGTAAACAAAGAACTCATCATCTTCGGA
AACATGCAAGAAATCTACGAATTTCATAATAACATATTCCTAAAGGAGCTGGAAAAATATGAACAGTTGCCAGAGGATGTTGGACATTGT
TTTGTTACTTGGGCAGACAAGTTTCAGATGTATGTCACATATTGCAAAAATAAGCCTGATTCTACTCAGCTGATATTGGAACATGCAGGG
TCCTATTTTGACCAAAGACTGAAGGGAGAGAAGGAAGCCAAGCGGGCTCTTTTGGATGCGAGGCATAACTACTTATTTGCAATTGTGGCT
TCCTGTTTGGACCTGAACAAAACCGAAGTGGAGGATGCCATTCTTGAAGGGAATCAGATTGAAAGAATTGATCAACTTTTTGCTGTTGGA
GGTCTCCGACACCTCATGTTTTACTATCAAGATGTGGAGGAAGCAGAAACAGGACAACTTGGCTCTCTAGGAGGGGTAAATCTTGTTTCT
GGAAAGATTAAAAAACCTAAGGTGTTCGTGACCGAGGGAAACGATGTGGCTCTTACTGGGGTATGTGTGTTCTTCATCAGGACTGACCCT
TCCAAAGCCATCACCCCTGACAACATCCACCAGGAGGTGAGTTTTAACATGTTAGATGCGGCAGATGGAGGCCTGCTCAACAGTGTGAGA
CGTTTGCTGTCGGACATCTTCATTCCTGCTCTCAGAGCCACGAGCCATGGCTGGGGCGAGCTCGAGGGCCTTCAGGACGCAGCTAACATT
CGCCAGGAGTTCTTGAGCTCCCTGGAAGGCTTTGTGAACGTCCTGTCGGGTGCACAGGAGAGTCTGAAGGAGAAGGTGAACCTTCGAAAG
TGTGACATACTTGAACTGAAAACCCTAAAGGAACCTACGGACTACTTGACTCTAGCAAATAACCCTGAGACTTTGGGAAAAATAGAGGAT
TGCATGAAAGTATGGATCAAACAGACAGAACAGGTTCTTGCTGAAAACAATCAGCTGCTGAAGGAAGCGGATGACGTTGGGCCACGAGCG
GAGCTGGAGCACTGGAAAAAAAGACTCTCCAAGTTTAACTACCTTTTGGAACAATTGAAAAGCCCGGATGTGAAGGCTGTGCTGGCAGTG
CTTGCGGCGGCCAAGTCGAAACTGCTGAAGACTTGGCGGGAGATGGATATTCGAATCACTGATGCAACTAATGAAGCAAAGGACAATGTG
AAATACTTGTATACACTTGAAAAATGTTGTGACCCTTTGTACAGCAGTGATCCCCTATCCATGATGGATGCTATTCCTACACTTATAAAT
GCAATTAAAATGATCTATAGTATCTCTCATTACTATAATACCTCTGAGAAGATCACATCTCTGTTTGTAAAGGTGACAAATCAGATTATA
TCTGCATGTAAAGCCTATATTACCAATAATGGAACCGCTTCCATCTGGAACCAGCCACAGGATGTTGTTGAAGAAAAAATACTATCTGCG
ATTAAACTGAAACAGGAATACCAGCTCTGCTTTCACAAGACAAAACAAAAGCTTAAACAAAATCCAAATGCAAAACAATTTGATTTTAGC
GAGATGTATATTTTTGGAAAATTCGAAACTTTTCACCGACGCCTTGCCAAGATAATAGACATCTTTACAACCCTCAAGACGTATTCAGTC
CTGCAAGATTCCACAATTGAAGGGCTGGAAGACATGGCCACTAAATACCAGGGCATTGTGGCAACCATAAAGAAAAAGGAATACAATTTC
CTAGACCAGCGGAAAATGGATTTTGACCAAGATTACGAAGAGTTTTGCAAGCAGACTAATGACCTTCATAACGAGTTGCGGAAGTTCATG
GATGTTACATTTGCAAAGATTCAAAACACAAATCAAGCTCTAAGAATGTTGAAGAAATTTGAAAGATTGAATATACCTAATCTTGGTATT
GATGACAAATATCAACTTATCCTTGAGAACTATGGGGCTGACATTGATATGATTTCAAAGCTGTATACAAAGCAGAAATACGATCCTCCT
CTGGCTCGAAACCAGCCTCCCATCGCTGGAAAGATTTTGTGGGCCCGCCAGCTCTTCCATAGGATTCAGCAGCCCATGCAGCTTTTCCAG
CAGCACCCAGCTGTGCTAAGCACGGCAGAAGCCAAACCTATAATTCGCAGTTACAACAGGATGGCCAAGGTCCTCCTGGAGTTTGAGGTC
CTCTTCCACAGGGCGTGGCTTCGGCAAATTGAAGAAATTCATGTAGGTCTTGAGGCTTCATTATTGGTGAAGGCTCCAGGCACAGGGGAA
TTGTTTGTAAACTTTGACCCTCAGATATTAATCTTATTTAGAGAAACAGAGTGCATGGCCCAGATGGGTCTGGAAGTCTCTCCACTGGCA
ACTTCCCTCTTCCAGAAACGAGATAGATACAAAAGGAACTTCAGTAACATGAAGATGATGCTAGCTGAATATCAGAGAGTGAAGTCAAAA
ATACCTGCTGCCATTGAGCAATTGATTGTCCCTCACTTGGCCAAAGTGGATGAAGCTCTCCAACCTGGCTTGGCTGCACTGACCTGGACA
TCACTGAATATTGAGGCTTATTTAGAAAACACTTTTGCAAAGATCAAGGACCTGGAGTTGCTGCTTGACAGGGTCAATGATTTGATTGAG
TTCCGCATTGATGCCATTCTAGAAGAAATGAGCAGCACGCCTCTTTGTCAGCTTCCCCAGGAGGAGCCACTAACCTGTGAAGAGTTTCTC
CAAATGACAAAGGATCTTTGTGTAAATGGTGCACAAATACTACATTTTAAAAGCTCATTAGTGGAGGAGGCAGTCAATGAGCTTGTAAAT
ATGTTGCTGGATGTGGAAGTTTTATCTGAAGAAGAAAGTGAAAAAATATCCAATGAGAATAGTGTTAATTACAAAAATGAAAGTTCAGCA
AAAAGAGAAGAAGGAAATTTTGACACCTTGACATCATCTATTAATGCCAGGGCCAATGCCCTGCTTTTGACGACAGTCACGAGGAAAAAG
AAAGAAACTGAGATGTTAGGGGAAGAAGCCCGCGAGTTACTCTCTCATTTCAACCATCAGAACATGGATGCTCTTCTGAAAGTTACAAGG
AATACACTAGAGGCCATTCGCAAACGTATTCATTCCTCTCACACAATTAACTTCCGGGACAGTAACAGTGCCTCTAACATGAAGCAGAAC
AGTTTGCCCATTTTCCGGGCAAGCGTCACTCTGGCCATTCCCAACATCGTCATGGCCCCTGCCCTGGAAGATGTACAGCAGACCCTGAAC
AAAGCCGTGGAGTGCATCATCAGTGTCCCTAAGGGGGTCAGACAGTGGAGCAGTGAACTGTTGTCCAAGAAAAAGATACAAGAAAGAAAA
ATGGCTGCTTTGCAGAGTAATGAAGACAGTGATTCTGATGTTGAAATGGGAGAAAATGAACTTCAAGATACCTTGGAGATAGCATCTGTA
AATTTACCCATTCCCGTGCAAACCAAGAACTATTATAAGAATGTTTCTGAAAACAAAGAGATTGTAAAATTAGTTTCTGTGCTTAGCACA
ATTATCAACTCCACCAAAAAGGAAGTTATTACATCCATGGATTGCTTCAAACGCTACAATCACATTTGGCAAAAGGGAAAAGAAGAAGCC
ATTAAGACATTTATTACACAGAGCCCCTTGCTTTCTGAATTTGAGTCCCAGATTCTCTATTTCCAAAACCTAGAGCAGGAAATTAATGCT
GAGCCTGAATATGTCTGTGTGGGTTCCATTGCTCTGTACACAGCTGACTTGAAGTTCGCCCTGACTGCTGAGACAAAGGCCTGGATGGTT
GTCATTGGACGCCACTGTAACAAAAAATACCGGAGTGAGATGGAAAACATTTTTATGCTTATTGAAGAATTCAATAAGAAACTAAATCGT
CCAATTAAGGACCTAGATGATATTCGGATTGCAATGGCAGCGCTGAAAGAAATAAGGGAGGAGCAAATCTCCATTGACTTTCAAGTAGGA
CCTATTGAGGAATCTTATGCCCTGCTTAACAGATATGGACTTCTGATAGCAAGGGAAGAGATAGACAAAGTTGATACACTGCACTATGCT
TGGGAGAAGCTGCTGGCACGTGCTGGCGAAGTCCAGAATAAATTAGTCTCACTGCAGCCCAGTTTCAAGAAAGAGCTTATTAGTGCTGTG
GAGGTATTCCTCCAAGATTGTCACCAGTTTTATCTGGACTATGATTTGAATGGTCCAATGGCTAGCGGCTTGAAGCCCCAGGAAGCCAGT
GACAGGCTTATCATGTTTCAGAATCAATTTGATAATATCTATCGGAAATACATCACATATACTGGAGGAGAGGAGCTTTTTGGCCTGCCA
GCTACACAGTATCCTCAGCTTCTTGAAATAAAGAAGCAACTAAATCTTCTACAGAAAATATATACTCTGTACAACAGTGTCATAGAAACT
GTAAATAGCTATTATGATATTCTTTGGTCAGAGGTGAATATTGAAAAAATTAACAATGAACTCTTAGAATTCCAGAACAGATGTCGAAAG
CTTCCCCGGGCCTTGAAGGACTGGCAGGCTTTTTTGGACCTGAAGAAGATCATTGATGATTTCAGCGAGTGTTGCCCGCTGCTGGAATAC
ATGGCCAGTAAAGCCATGATGGAGCGGCACTGGGAAAGGATAACCACCCTCACCGGGCACAGTCTGGATGTGGGGAATGAAAGCTTTAAG
TTAAGAAATATCATGGAGGCACCTCTTCTGAAATATAAAGAGGAAATAGAGGACATCTGTATCAGTGCGGTGAAAGAGAGAGACATTGAG
CAAAAGCTGAAGCAAGTGATTAATGAATGGGACAATAAAACATTCACCTTCGGCAGCTTTAAAACCCGTGGAGAGCTCCTCTTGAGAGGA
GACAGTACCTCGGAAATCATCGCCAACATGGAGGACAGCTTGATGTTGCTGGGATCCCTACTGAGCAACAGGTACAATATGCCATTCAAA
GCCCAGATTCAAAAATGGGTGCAGTACCTTTCCAACTCAACAGACATCATCGAGAGCTGGATGACGGTGCAAAACCTGTGGATTTATTTA
GAAGCTGTCTTTGTGGGAGGAGACATTGCCAAGCAGCTGCCCAAGGAAGCCAAGCGGTTTTCTAACATAGATAAATCTTGGGTGAAGATC
ATGACTCGGGCACATGAAGTGCCCAGTGTAGTCCAGTGCTGTGTTGGAGATGAGACCCTGGGGCAGCTGTTACCACACTTGCTGGACCAG
TTGGAAATATGCCAGAAATCCCTTACTGGGTACTTGGAGAAAAAACGACTGTGCTTTCCTCGGTTTTTCTTCGTCTCAGATCCTGCCCTT
CTAGAGATTCTGGGGCAGGCGTCGGACTCCCACACTATACAGGCCCATTTGCTGAATGTGTTTGACAACATTAAATCTGTCAAGTTCCAC
GAAAAGATCTATGATCGAATTCTGTCAATTTCCTCTCAAGAGGGTGAGACGATTGAATTGGATAAACCTGTCATGGCAGAGGGCAATGTG
GAAGTTTGGCTTAATTCTCTTTTGGAAGAATCTCAGTCCTCATTGCATCTTGTGATTCGCCAGGCAGCCGCAAATATTCAAGAAACAGGT
TTCCAACTAACTGAATTTCTTTCATCCTTCCCTGCTCAGGTTGGATTATTAGGAATTCAGATGATATGGACACGGGATTCAGAAGAAGCC
CTTAGAAATGCCAAGTTTGATAAAAAAATCATGCAGAAAACTAATCAGGCTTTCCTGGAGCTACTCAATACATTGATAGACGTCACCACG
AGGGATCTGAGTTCCACGGAACGAGTGAAATACGAGACTCTGATTACTATTCATGTGCACCAAAGGGATATCTTTGATGACCTGTGTCAT
ATGCATATCAAGAGTCCCATGGACTTTGAGTGGCTGAAACAGTGCAGATTTTACTTTAACGAAGATTCTGACAAGATGATGATTCACATC
ACAGATGTGGCGTTCATATACCAGAATGAATTTTTAGGCTGCACTGACAGGCTTGTAATAACTCCACTTACAGACAGATGTTACATCACG
CTGGCTCAAGCTCTGGGAATGAGCATGGGGGGAGCCCCTGCTGGACCTGCAGGCACAGGCAAAACAGAAACCACTAAAGACATGGGACGA
TGCCTCGGGAAATACGTCGTGGTTTTCAATTGTTCAGACCAGATGGATTTCCGAGGACTTGGACGGATTTTTAAGGGACTGGCACAGTCT
GGATCCTGGGGTTGTTTTGATGAATTTAACCGTATTGATCTACCAGTTCTCTCGGTTGCAGCCCAGCAAATTTCCATTATTCTGACATGT
AAAAAGGAGCACAAAAAGTCTTTTATCTTTACTGATGGAGATAATGTGACTATGAACCCTGAATTTGGGCTTTTCTTAACCATGAATCCT
GGCTATGCCGGACGGCAGGAACTCCCTGAAAACTTGAAGATTAATTTCCGCTCAGTGGCCATGATGGTGCCTGACCGTCAGATTATCATA
AGGGTGAAGTTGGCTAGTTGTGGCTTCATTGACAACGTTGTTTTGGCCAGGAAGTTTTTCACGCTCTACAAACTGTGTGAGGAGCAGCTT
TCTAAGCAGGTTCATTATGACTTTGGCCTGCGTAACATTCTGTCAGTTCTTCGGACCTTGGGAGCAGCAAAAAGAGCCAATCCAATGGAT
ACGGAGTCCACGATTGTCATGCGTGTACTACGGGACATGAATCTTTCTAAACTGATTGATGAGGATGAACCCTTGTTTTTGAGTTTGATT
GAAGATCTCTTTCCAAATATTCTTCTGGACAAGGCAGGTTACCCTGAACTGGAAGCAGCAATTAGTAGACAGGTTGAAGAAGCTGGTTTA
ATCAACCATCCTCCTTGGAAACTGAAGGTCATCCAGCTATTCGAAACGCAGAGAGTGCGACATGGGATGATGACTCTGGGGCCCAGTGGG
GCTGGGAAGACCACCTGCATCCACACCTTGATGAGAGCCATGACAGATTGTGGAAAACCACATCGGGAAATGAGGATGAATCCCAAAGCG
ATTACTGCCCCACAGATGTTTGGTCGGCTGGACGTTGCCACAAATGACTGGACTGATGGGATATTTTCTACGCTTTGGAGGAAAACATTA
AGAGCAAAGAAAGGGGAACATATCTGGATAATTCTTGATGGTCCAGTAGATGCCATCTGGATTGAAAATCTGAATTCTGTTTTGGATGAT
AACAAAACTCTAACCCTTGCCAATGGTGATCGGATTCCCATGGCTCCAAACTGCAAGATCATTTTCGAGCCTCATAACATTGACAATGCT
TCTCCTGCCACCGTCTCAAGAAATGGAATGGTTTTCATGAGCTCTTCTATCCTTGATTGGAGTCCTATTCTTGAGGGTTTTCTTAAGAAA
CGCTCACCTCAAGAAGCAGAAATTCTTCGTCAGCTGTACACCGAGTCTTTCCCAGACTTGTATCGCTTCTGTATCCAGAACTTAGAATAC
AAGATGGAGGTGCTGGAGGCCTTTGTCATCACACAGAGCATTAACATGCTTCAAGGCCTGATTCCTCTGAAGGAGCAAGGCGGGGAGGTG
AGCCAGGCTCACCTGGGGCGGCTGTTCGTGTTCGCGCTGCTGTGGAGCGCGGGGGCGGCGCTGGAGCTGGACGGACGGCGCCGCCTGGAG
CTCTGGCTGCGCTCTCGGCCCACAGGGACGCTGGAGCTGCCGCCGCCAGCGGGGCCCGGGGACACCGCCTTCGACTACTATGTGGCGCCC
GATGGTACATGGACGCACTGGAACACGCGTACCCAGGAATACCTGTATCCGTCTGATACCACCCCAGAGTATGGTTCTATTCTGGTGCCA
AATGTTGACAATGTGAGGACTGACTTTCTAATTCAAACCATTGCTAAACAGGGCAAGGCTGTGCTATTAATTGGTGAACAAGGAACAGCC
AAAACAGTAATAATTAAAGGATTTATGTCAAAATATGATCCTGAATGTCACATGATCAAGAGTCTGAATTTTTCTTCTGCAACCACCCCA
CTGATGTTCCAGAGGACGATAGAGAGCTATGTGGATAAACGAATGGGTACAACATATGGCCCTCCTGCGGGAAAGAAGATGACTGTTTTT
ATTGATGATGTGAATATGCCAATAATCAATGAGTGGGGAGATCAGGTTACGAATGAGATAGTGCGACAGCTGATGGAACAAAATGGATTC
TATAATCTAGAGAAGCCTGGGGAGTTCACCAGCATCGTGGACATCCAGTTTTTGGCAGCCATGATCCATCCTGGTGGTGGACGCAATGAC
ATACCCCAAAGACTCAAGAGGCAGTTCTCTATATTTAATTGCACGTTGCCCTCTGAAGCTTCTGTGGACAAGATCTTTGGTGTGATTGGG
GTAGGCCACTACTGTACTCAGAGGGGTTTCTCAGAAGAAGTGAGAGATTCTGTGACAAAATTGGTGCCTCTGACACGCCGACTATGGCAG
ATGACCAAGATTAAAATGCTTCCTACCCCTGCAAAATTCCATTATGTGTTTAACCTACGAGATCTTTCTCGGGTCTGGCAGGGAATGCTG
AACACTACTTCAGAGGTCATCAAGGAACCAAATGATCTGTTAAAGCTGTGGAAGCATGAGTGTAAACGTGTTATAGCTGACCGTTTCACA
GTGTCCAGTGATGTGACCTGGTTTGATAAGGCTTTAGTAAGTTTGGTAGAGGAGGAGTTTGGTGAAGAGAAAAAACTCTTGGTGGATTGT
GGAATTGACACATATTTTGTGGATTTCTTGAGAGATGCACCTGAAGCTGCAGGTGAAACATCTGAAGAGGCTGATGCTGAAACACCTAAA
ATTTATGAGCCAATTGAATCTTTTAGTCACCTAAAAGAGCGTCTGAATATGTTCCTGCAGCTCTATAATGAGAGCATCCGTGGCGCCGGC
ATGGACATGGTGTTCTTTGCAGATGCCATGGTTCACTTAGTCAAGATCTCTCGTGTCATTCGTACTCCTCAGGGAAATGCCCTCCTGGTC
GGGGTGGGCGGATCAGGAAAGCAGAGCCTGACGAGGTTGGCTTCATTCATTGCTGGCTACGTTTCCTTCCAGATCACTCTGACGAGATCC
TACAACACATCAAATCTGATGGAAGATCTGAAGGTTTTGTATCGAACAGCTGGTCAGCAAGGCAAAGGAATCACTTTTATTTTCACAGAC
AATGAGATTAAAGATGAGTCATTTTTGGAATATATGAACAATGTTTTATCATCAGGTGAGGTCTCTAACCTATTTGCTCGAGATGAAATT
GATGAAATTAATAGCGACCTGGCATCAGTCATGAAAAAAGAATTCCCCAGGTGCCTTCCTACCAATGAGAACCTGCACGACTACTTCATG
AGTCGGGTCCGACAGAACCTTCATATTGTGCTCTGCTTCTCGCCAGTGGGGGAGAAATTTCGAAACAGAGCTTTGAAGTTCCCTGCCCTA
ATTTCAGGATGCACAATTGACTGGTTCAGCCGATGGCCCAAAGATGCTTTAGTTGCTGTGTCTGAACACTTCCTCACTTCCTATGATATT
GACTGCAGTTTGGAAATCAAGAAGGAGGTGGTCCAATGCATGGGCTCCTTCCAGGATGGGGTGGCTGAGAAGTGTGTTGATTATTTTCAG
AGATTCCGACGTTCTACCCACGTGACGCCCAAATCATACCTCTCCTTTATTCAGGGCTATAAGTTCATATATGGAGAAAAGCATGTGGAG
GTGCGGACCCTGGCCAACAGAATGAATACTGGATTGGAAAAGCTCAAAGAAGCTTCAGAGTCTGTTGCAGCCTTGAGTAAAGAACTGGAA
GCGAAAGAAAAGGAGCTACAAGTGGCCAACGATAAAGCCGACATGGTCTTAAAAGAAGTGACAATGAAAGCACAGGCTGCTGAAAAGGTC
AAGGCTGAGGTACAGAAGGTGAAGGACAGGGCCCAGGCCATTGTGGACAGCATCTCTAAAGACAAAGCCATTGCTGAAGAAAAACTGGAA
GCAGCAAAACCAGCTTTAGAAGAGGCAGAAGCTGCATTGCAGACCATCAGGCCTTCGGACATCGCCACTGTTCGCACGTTGGGCCGCCCC
CCTCACCTCATCATGCGGATCATGGATTGCGTACTGCTGCTGTTTCAAAGGAAAGTCAGTGCTGTGAAAATTGACCTGGAAAAAAGCTGT
ACCATGCCCTCCTGGCAGGAATCCTTAAAATTGATGACTGCAGGGAACTTTTTACAGAACTTACAGCAATTCCCAAAAGACACAATCAAT
GAAGAGGTGATAGAATTTTTGAGTCCTTACTTTGAAATGCCTGACTATAACATCGAAACTGCTAAACGCGTATGTGGAAATGTAGCTGGT
CTTTGTTCCTGGACGAAAGCTATGGCTTCCTTCTTTTCTATAAACAAAGAAGTACTGCCTCTGAAGGCCAACTTGGTGGTGCAAGAGAAT
CGCCATCTCCTGGCCATGCAGGATCTGCAGAAAGCCCAGGCCGAGTTGGATGACAAGCAGGCGGAACTTGACGTGGTGCAGGCTGAGTAT
GAACAGGCCATGACTGAAAAGCAGACCTTGCTTGAAGATGCAGAGCGATGCAGACACAAGATGCAGACAGCTTCCACGCTCATCAGTGGC
TTGGCAGGTGAAAAAGAAAGATGGACAGAGCAAAGCCAAGAGTTTGCTGCACAAACTAAAAGACTTGTAGGGGATGTACTGTTGGCTACA
GCTTTTCTATCTTATTCTGGTCCATTTAACCAAGAGTTTCGTGATCTTCTGTTAAATGACTGGCGGAAGGAAATGAAAGCCCGGAAAATT
CCATTTGGAAAGAACCTAAATCTCAGTGAGATGTTGATTGATGCTCCTACTATTAGTGAATGGAACCTCCAAGGTCTGCCAAATGATGAC
TTGTCCATTCAAAATGGAATTATTGTCACGAAGGCATCTCGTTACCCTTTGTTAATTGATCCACAGACTCAAGGCAAGATCTGGATTAAA
AATAAAGAAAGCCGAAATGAACTCCAGATCACGTCTTTAAATCACAAGTACTTCAGAAACCACCTGGAAGACAGCCTTTCTCTTGGAAGG
CCTTTGCTTATTGAAGATGTTGGAGAGGAACTAGATCCAGCACTAGATAATGTTTTGGAAAGAAACTTCATTAAAACTGGGTCTACCTTT
AAGGTGAAAGTTGGTGACAAGGAAGTAGATGTGTTGGATGGCTTTAGACTCTACATTACCACCAAATTGCCTAACCCAGCCTACACCCCT
GAGATAAGTGCCCGTACCTCCATCATTGACTTCACTGTCACCATGAAAGGTCTAGAAGATCAGTTACTGGGGAGGGTCATTCTCACAGAG
AAGCAGGAATTGGAGAAAGAAAGAACTCATCTGATGGAAGATGTAACTGCAAACAAAAGAAGGATGAAGGAACTAGAAGATAACTTGCTT
TACCGCCTGACAAGTACCCAGGGGTCCCTGGTAGAAGATGAAAGTCTCATTGTCGTGCTGAGTAACACAAAAAGGACAGCCGAGGAGGTG
ACACAGAAGCTAGAAATTTCTGCTGAGACAGAAGTTCAAATTAACTCAGCCCGGGAGGAATACAGACCTGTGGCTACGCGGGGCAGCATC
CTCTACTTCCTCATTACTGAGATGCGCTTGGTTAATGAGATGTATCAGACTTCGCTTCGCCAGTTTCTGGGCTTATTTGACCTTTCCTTA
GCCAGGTCTGTCAAGAGCCCGATTACAAGCAAGAGGATTGCTAATATCATCGAGCACATGACCTACGAGGTTTATAAGTATGCTGCCCGA
GGGCTGTACGAGGAGCACAAATTCCTGTTCACCTTGTTGCTTACCCTAAAGATTGACATCCAGAGGAACCGAGTCAAGCATGAAGAGTTT
CTCACTCTTATTAAAGGAGGTGCCTCATTAGACCTTAAAGCTTGTCCTCCAAAACCATCAAAATGGATCCTGGACATAACATGGCTGAAT
TTGGTGGAACTTAGCAAACTCAGACAGTTTTCAGATGTCCTTGACCAGATATCGAGAAATGAGAAAATGTGGAAAATTTGGTTTGATAAG
GAAAACCCGGAGGAGGAACCTCTTCCAAATGCCTATGATAAATCTCTTGACTGCTTCAGACGTCTTCTCCTTATTAGATCCTGGTGTCCT
GACAGAACCATCGCCCAGGCCCGCAAGTACATCGTGGACTCCATGGGAGAAAAATATGCCGAAGGTGTTATTTTAGACTTGGAGAAGACG
TGGGAGGAATCTGATCCACGGACGCCACTCATCTGTCTCCTGTCTATGGGCTCAGACCCCACAGATTCCATCATTGCCTTGGGGAAGAGA
TTAAAAATAGAAACCCGTTATGTGTCCATGGGCCAGGGCCAGGAAGTCCATGCTCGGAAGCTCTTGCAGCAGACCATGGCGAACGGAGGA
TGGGCACTTCTGCAGAACTGCCATCTGGGACTTGATTTCATGGATGAGCTGATGGACATAATCATAGAAACTGAGCTTGTACATGATGCG
TTCCGCCTCTGGATGACCACCGAGGCTCATAAGCAGTTTCCCATTACACTCCTTCAGATGTCCATTAAATTTGCCAACGATCCTCCACAA
GGACTCCGGGCAGGACTGAAAAGAACATATAGTGGTGTCAGCCAAGACCTGCTGGACGTGAGCTCTGGGTCCCAGTGGAAGCCCATGCTG
TACGCAGTGGCTTTCCTGCACTCCACTGTCCAGGAGAGGCGCAAGTTCGGTGCCCTGGGGTGGAATATCCCCTACGAATTTAACCAAGCG
GACTTTAATGCCACTGTGCAGTTCATCCAAAACCACTTGGATGACATGGATGTCAAAAAGGGTGTCTCCTGGACCACCATCCGCTACATG
ATAGGAGAGATTCAATATGGAGGCAGAGTCACTGACGACTATGATAAGAGATTGTTGAACACATTTGCTAAGGTTTGGTTCAGTGAAAAT
ATGTTTGGACCAGATTTCAGTTTTTACCAAGGATACAATATTCCAAAATGCAGCACAGTGGATAACTATCTTCAGTATATCCAGAGTTTG
CCTGCCTATGACAGCCCTGAGGTGTTTGGGCTGCACCCCAATGCTGACATCACCTACCAGAGCAAGCTGGCCAAGGACGTGCTGGACACC
ATCCTAGGCATCCAACCCAAGGACACCTCTGGTGGAGGGGATGAGACCCGGGAGGCGGTGGTGGCCCGGCTGGCTGATGATATGCTGGAG
AAGCTGCCCCCAGACTATGTCCCCTTTGAAGTAAAAGAGAGGCTGCAGAAGATGGGGCCATTCCAGCCTATGAACATTTTCCTCAGGCAG
GAAATAGACAGAATGCAAAGGGTACTCAGCCTTGTCCGCAGCACCCTCACTGAGCTGAAACTTGCTATTGATGGCACCATCATCATGAGC
GAAAATCTGCGAGATGCATTGGATTGCATGTTTGATGCTAGAATCCCTGCTTGGTGGAAAAAAGCTTCTTGGATTTCTAGTACACTGGGT
TTCTGGTTTACTGAACTTATAGAAAGAAACAGCCAGTTTACCTCGTGGGTTTTCAATGGCCGACCTCACTGCTTTTGGATGACGGGTTTT
TTTAACCCCCAGGGATTTTTAACTGCAATGCGACAGGAAATAACTCGGGCCAACAAAGGCTGGGCTCTGGACAATATGGTGCTTTGCAAT
GAAGTCACCAAATGGATGAAGGACGACATTTCTGCCCCTCCCACAGAGGGTGTCTATGTCTATGGCTTATATCTTGAAGGTGCTGGCTGG
GACAAGAGGAACATGAAACTCATTGAATCAAAGCCAAAAGTGCTCTTTGAGTTGATGCCTGTCATAAGGATTTATGCAGAAAACAATACT
TTACGAGATCCTCGGTTTTACTCCTGTCCCATCTATAAGAAGCCAGTTCGAACGGACTTGAACTACATTGCCGCTGTGGATCTCAGGACA
GCCCAGACCCCTGAACACTGGGTGCTCCGTGGGGTTGCCCTTCTGTGTGATGTCAAGTAACATGTGGGGAGTGTCCCCACCCAATGCTTT
GGAAAATGCAAGATCTAAATTATTGTAACCTTTATTTCTGTATGACTGCTGGACAGTGTATGTTAGGTCGTTTATGCAATTAATGAGCTG
CATAGGTTTTCCCCACTCCTTAATTGGATGCTTATATTTTACTTGTTTCATCATTAGTGACCAATGTCTGAGTTTGTTGAAAATGTTATT
TAGTGATATAAAAGTAAATTTACAGCATCCTAATGAAGTGTGGCCCTCAAATCCACAGTAGTATATTTTCTTCTTACTTCGCTCCGAAGA
CTGACTAGGGTAAGCAGACAGTATTTCTCTGGGAGGAATTATTCTTCTGTTAACGTGGCCTGGTAACAGCCAAGTTCTTGAAGGTAACAG
GGCAAGTCTGTGCTGATTTTGCTTCTATTGCCTTTCGTATTTAGGTCAAGTTAAGAGACTTATTTTCAGGGTTTCAAGCAGCCAATTAAA
AATACCTTTTAAAAAATAGAAGGAAATAGAAGAATGGATTAAGAATGTAAATAGAAAATTTATGTAAACATAGAGAATAAACGTAGAACA
ATGCTTAAGCCTACTTATAATTAATAATGAAATACTAATTGATAATTCTTATAATAAAAATTAAAGCTAAAAGTAAATGATAGCATGCTC
TCAGTAAAACTGATCCACTCACAAATTGCTGGAGCAATGTAAATCAACCCAACCTTTTTGTAAAATGATTAAATACAGAAAGAGCCATAA
AAATATTCACACCCTTGGATCTTTGTTTTCTCTACATCAAGGAAACAATTTAAAAGACTGAAAACAGTCTATATAAAATTGCATTTAATA
ACAGAAAAAAATGGAAAAATCATAAATATTCAATAGTCAGGCTATGGTTAAGGAAATTAAGAGATATTTGGCAACCATAAAAAACAATTT
TGAAGATTCCATAATATGAAATGGTAGACCCAGACTGTTAAGTGAAAGATTTAGTTTACAAAATATTGAGCACACTGTGATTATAACAGC
AAATATATTTGCATGTGGACAAAGATTAGATGGCAAGATAGAAAAATAAGAACAGATGTGATAGCAAGAATTATAGTTGGCTTGAAAAAA
TGTGATGATCAGGAGAAAAAATAAAAAAAGGGTAGAAATATTAGACGGTGCGTAGGGACTTTCTATGGACTTTTATTAATTAGGAAACAT
TATCAAAGGAACTTTTCACGTATTTTTCTTTAAATTCTGGTTAGATGTTATTAATAATTCTTCATCTAACCTACTGACTAGAAAATATAG
TCAGTACTAAATTAGAATTGTGGTTTATAAACTTTTGGTTAGCTCTGGATCTGTATAACTGCATTTTTTTGGATAAACAGTTTTTGGTAG
GTGGATACCGGGAGACAAGTGTGGGTCCCTCTCACTGGGCTTCATTCTGTGGACCAGGATCATTATTTCATGCTCATGATCATGAGAGTT
AGGACTGAGTGGCTCCTGTGACTCCCACCATCTTAGATGATACTGTTTTCTTGTGAGTTCTTTCTTTTGGTGTGGATTAGTATATCAGTT
GATTTGTGTGAATTGTGGTGAAACAATCATTTCATTTTGAAAAGCAAGTAATGAAAATGTCAACATCATAGGAATTAATAAAATGTTTTT

>94199_94199_1_TRIO-DNAH5_TRIO_chr5_14391099_ENST00000344204_DNAH5_chr5_13931353_ENST00000265104_length(amino acids)=6011AA_BP=1404
MSGSSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEMKAMDVLPILKEKVAYLSGGRDKRGGPILTF
PARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFE
TNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDILAKKELPQDLEGARNMIEEHSQLKKKVIKA
PIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNK
GLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIRQIASQLEQEWKAFAAALDERSTLLDMSSIF
HQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYSEVSQDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDV
IHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYTNADKLLEA
AEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTT
LQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKIKLELFLQLRIFERDAIDIISDLESWNDELS
QQMNDFDTEDLTIAEQRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHR
KHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKTHQSALQVQQKAEAMLQANHYDMDMIRDCAE
KVASHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRN
ADVFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQYVVFERSAKQALEWIHDNGEFYLSTHTSTGS
SIQHTQELLKEHEEFQITAKQTKERVKLLIQLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQ
LDIIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFGNMQEIYEF
HNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAGSYFDQRLKGEKEAKRALLDARHNYLFAIVASCLDLNKT
EVEDAILEGNQIERIDQLFAVGGLRHLMFYYQDVEEAETGQLGSLGGVNLVSGKIKKPKVFVTEGNDVALTGVCVFFIRTDPSKAITPDN
IHQEVSFNMLDAADGGLLNSVRRLLSDIFIPALRATSHGWGELEGLQDAANIRQEFLSSLEGFVNVLSGAQESLKEKVNLRKCDILELKT
LKEPTDYLTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLKEADDVGPRAELEHWKKRLSKFNYLLEQLKSPDVKAVLAVLAAAKSKL
LKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYSSDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYIT
NNGTASIWNQPQDVVEEKILSAIKLKQEYQLCFHKTKQKLKQNPNAKQFDFSEMYIFGKFETFHRRLAKIIDIFTTLKTYSVLQDSTIEG
LEDMATKYQGIVATIKKKEYNFLDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNTNQALRMLKKFERLNIPNLGIDDKYQLIL
ENYGADIDMISKLYTKQKYDPPLARNQPPIAGKILWARQLFHRIQQPMQLFQQHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLR
QIEEIHVGLEASLLVKAPGTGELFVNFDPQILILFRETECMAQMGLEVSPLATSLFQKRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQL
IVPHLAKVDEALQPGLAALTWTSLNIEAYLENTFAKIKDLELLLDRVNDLIEFRIDAILEEMSSTPLCQLPQEEPLTCEEFLQMTKDLCV
NGAQILHFKSSLVEEAVNELVNMLLDVEVLSEEESEKISNENSVNYKNESSAKREEGNFDTLTSSINARANALLLTTVTRKKKETEMLGE
EARELLSHFNHQNMDALLKVTRNTLEAIRKRIHSSHTINFRDSNSASNMKQNSLPIFRASVTLAIPNIVMAPALEDVQQTLNKAVECIIS
VPKGVRQWSSELLSKKKIQERKMAALQSNEDSDSDVEMGENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKE
VITSMDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILYFQNLEQEINAEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNK
KYRSEMENIFMLIEEFNKKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKVDTLHYAWEKLLARA
GEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMASGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLL
EIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSECCPLLEYMASKAMME
RHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIA
NMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVP
SVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRIL
SISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDK
KIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQ
NEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDE
FNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCG
FIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNIL
LDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFG
RLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRN
GMVFMSSSILDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKMEVLEAFVITQSINMLQGLIPLKEQGGEVSQAHLGRL
FVFALLWSAGAALELDGRRRLELWLRSRPTGTLELPPPAGPGDTAFDYYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTD
FLIQTIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPI
INEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQR
GFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVTWF
DKALVSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFAD
AMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESF
LEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDW
FSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRM
NTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEE
AEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLS
PYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQ
TLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRKEMKARKIPFGKNLNL
SEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVG
EELDPALDNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKER
THLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEM
RLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGA
SLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQAR
KYIVDSMGEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETRYVSMGQGQEVHARKLLQQTMANGGWALLQNCH
LGLDFMDELMDIIIETELVHDAFRLWMTTEAHKQFPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPMLYAVAFLHS
TVQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGPDFSF
YQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVP
FEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWISSTLGFWFTELIE
RNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLI

--------------------------------------------------------------
>94199_94199_2_TRIO-DNAH5_TRIO_chr5_14391099_ENST00000509967_DNAH5_chr5_13931353_ENST00000265104_length(transcript)=19694nt_BP=4223nt
ATTTGGGATATCTAGAGGTTGTTTGTTGGTGTTCTGGGATCCTGAGGGACACTGCCAACTGTTAACCTTTGGCAGATAGTGACTGTTTTA
CTTCGATTTTATTTTCGTGGTAACCGTTTTTTAAAAAAGATTAATAAATTACCCAAGAGGACATGGCAGAAGGGTTTCGAAAAAACGATG
AAATGAAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGGAGAGATAAACGTGGAGGTCCCATTTTAA
CGTTTCCGGCCCGCAGCAATCATGACAGAATACGACAGGAGGATCTCAGGAGACTCATTTCCTATCTAGCCTGTATTCCCAGCGAGGAGG
TCTGCAAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAGCCCCTTCTGAAGATCCTGCAGGAGTCCT
TCCCCTGCTGCATCCATGTGGCCCTGATCATCAAGCCAGACAACTTCTGGCAGAAACAGAGGACTAATTTTGGCAGTTCTAAATTTGAAT
TTGAGACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACTCCTGAGTTTGATGGCTGCCTGGAATACA
ACCACGAAGAATGGATTGAAATCAGAGTTGCTTTTGAAGACTACATTAGCAATGCCACCCACATGCTGTCTCGGCTGGAGGAACTTCAGG
ACATCCTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAACATTCTCAGCTGAAGAAGAAGGTGATTA
AGGCCCCCATCGAGGACCTGGATTTGGAGGGACAGAAGCTGCTTCAGAGGATACAGAGCAGTGAAAGCTTTCCCAAAAAGAACTCAGGCT
CAGGCAATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCACTCGACACGGCAGCATCTGCACCAGATGT
GGCATGTGAGGAAGCTGAAGCTGGACCAGTGCTTCCAGCTGAGGCTGTTTGAACAGGATGCTGAGAAGATGTTTGACTGGATCACACACA
ACAAAGGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAGCTTCAGACGCAGCACAATCACTTTGCCA
TGAACTGTATGAACGTGTATGTAAATATAAACCGCATCATGTCGGTGGCCAATCGTCTGGTGGAGTCTGGCCACTATGCCTCGCAGCAGA
TCAGGCAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAGCGGAGCACCTTGCTGGACATGTCCTCCA
TTTTCCACCAGAAGGCCGAAAAGTATATGAGCAACGTGGATTCATGGTGTAAAGCTTGCGGTGAGGTAGACCTTCCCTCAGAGCTGCAGG
ACCTAGAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCTGAGGTCAGCCAAGATGGGAAGTCGCTCC
TTGACAAGCTCCAGCGGCCCTTGACTCCCGGCAGCTCCGATTCCCTGACAGCCTCTGCCAACTACTCCAAGGCCGTGCACCATGTCCTGG
ATGTCATCCACGAGGTGCTGCACCACCAGCGGCAGCTGGAGAACATCTGGCAACACCGCAAGGTCCGGCTGCATCAGAGGCTGCAGCTGT
GTGTTTTCCAGCAGGACGTTCAGCAGGTGCTAGACTGGATCGAGAACCACGGAGAAGCATTTCTGAGCAAACATACAGGTGTGGGGAAAT
CTCTTCATCGGGCCAGAGCATTGCAGAAACGTCATGAAGATTTTGAAGAAGTGGCACAGAACACATACACCAATGCGGATAAATTACTGG
AAGCAGCAGAACAGCTGGCTCAGACTGGGGAATGTGACCCCGAAGAGATTTATCAGGCTGCCCATCAGCTGGAAGACCGGATTCAAGATT
TCGTTCGGCGTGTTGAGCAGCGAAAGATCCTACTGGACATGTCAGTGTCCTTTCACACCCATGTGAAAGAGCTGTGGACGTGGCTGGAGG
AGCTGCAGAAGGAGCTGCTGGACGACGTGTATGCCGAGTCGGTGGAGGCCGTGCAGGACCTCATCAAGCGCTTTGGCCAGCAGCAGCAGA
CCACCCTGCAGGTGACTGTCAACGTGATCAAGGAAGGGGAGGACCTCATCCAGCAGCTCAGGGACTCTGCCATCTCCAGTAACAAGACCC
CCCACAACAGCTCCATCAACCACATTGAGACGGTGCTGCAGCAGCTGGACGAGGCGCAGTCGCAGATGGAGGAGCTCTTCCAGGAGCGCA
AGATCAAGCTGGAGCTCTTCCTGCAGCTGCGCATCTTCGAGAGGGACGCCATCGACATTATCTCAGACCTCGAGTCTTGGAATGATGAGC
TTTCTCAGCAAATGAATGACTTCGACACAGAAGATCTCACGATTGCAGAGCAGCGCCTCCAGCACCATGCAGACAAAGCCTTGACCATGA
ACAACTTGACTTTTGACGTCATCCACCAAGGGCAAGATCTTCTGCAGTATGTCAATGAGGTCCAGGCCTCTGGTGTGGAGCTGCTGTGTG
ATAGAGATGTAGACATGGCAACTCGGGTCCAGGACCTGCTGGAGTTTCTTCATGAAAAACAGCAGGAATTGGATTTAGCCGCAGAGCAGC
ATCGGAAACACCTGGAGCAGTGCGTGCAGCTGCGCCACCTGCAGGCAGAAGTGAAACAGGTGCTGGGTTGGATCCGCAACGGAGAGTCCA
TGTTAAATGCCGGACTTATCACAGCCAGCTCGTTACAAGAGGCAGAGCAGCTCCAGCGAGAGCACGAGCAGTTCCAGCATGCCATTGAGA
AAACACATCAGAGCGCGCTGCAGGTGCAGCAGAAGGCAGAAGCCATGCTACAGGCCAACCACTACGACATGGACATGATCCGGGACTGCG
CCGAGAAGGTGGCGTCTCACTGGCAACAGCTCATGCTCAAGATGGAAGATCGCCTCAAGCTCGTCAACGCCTCTGTCGCTTTCTACAAAA
CCTCAGAGCAGGTCTGCAGCGTCCTCGAGAGCCTGGAACAGGAGTACAAGAGAGAAGAAGACTGGTGTGGCGGGGCGGATAAGCTGGGCC
CAAACTCTGAGACGGACCACGTGACGCCCATGATCAGCAAGCACCTGGAGCAGAAGGAGGCATTCCTGAAGGCTTGCACCCTTGCTCGGA
GGAATGCAGACGTCTTCCTGAAATACCTGCACAGGAACAGCGTGAACATGCCAGGAATGGTGACGCACATCAAAGCTCCTGAACAGCAAG
TGAAAAATATCTTGAATGAACTCTTCCAACGGGAGAACAGGGTATTGCATTACTGGACCATGAGGAAGAGACGGCTGGACCAGTGTCAGC
AGTACGTGGTCTTTGAGAGGAGTGCCAAGCAGGCTTTGGAATGGATCCATGACAATGGCGAGTTCTACCTTTCCACACACACCTCCACGG
GCTCCAGTATACAGCACACCCAGGAGCTCCTGAAAGAGCACGAGGAGTTCCAGATAACTGCAAAGCAAACCAAAGAGAGAGTGAAGCTAT
TGATACAGCTGGCTGATGGCTTTTGTGAAAAAGGGCATGCCCATGCGGCAGAGATAAAAAAATGTGTTACTGCTGTGGATAAGAGGTACA
GAGATTTCTCTCTGCGGATGGAGAAGTACAGGACCTCTTTGGAAAAAGCCCTGGGGATTTCTTCAGATTCCAACAAATCGAGTAAAAGTC
TCCAGCTAGATATCATTCCAGCCAGTATCCCTGGCTCAGAGGTGAAACTTCGAGATGCTGCTCATGAACTTAATGAAGAGAAGCGGAAAT
CTGCCCGCAGGAAAGAGTTCATAATGGCTGAGCTCATTCAAACTGAAAAGGCTTATGTAAGAGACCTCCGGGAATGTATGGATACGTACC
TGTGGGAAATGACCAGTGGCGTGGAAGAGATTCCACCTGGCATTGTAAACAAAGAACTCATCATCTTCGGAAACATGCAAGAAATCTACG
AATTTCATAATAACATATTCCTAAAGGAGCTGGAAAAATATGAACAGTTGCCAGAGGATGTTGGACATTGTTTTGTTACTTGGGCAGACA
AGTTTCAGATGTATGTCACATATTGCAAAAATAAGCCTGATTCTACTCAGCTGATATTGGAACATGCAGGGTCCTATTTTGACCAAAGAC
TGAAGGGAGAGAAGGAAGCCAAGCGGGCTCTTTTGGATGCGAGGCATAACTACTTATTTGCAATTGTGGCTTCCTGTTTGGACCTGAACA
AAACCGAAGTGGAGGATGCCATTCTTGAAGGGAATCAGATTGAAAGAATTGATCAACTTTTTGCTGTTGGAGGTCTCCGACACCTCATGT
TTTACTATCAAGATGTGGAGGAAGCAGAAACAGGACAACTTGGCTCTCTAGGAGGGGTAAATCTTGTTTCTGGAAAGATTAAAAAACCTA
AGGTGTTCGTGACCGAGGGAAACGATGTGGCTCTTACTGGGGTATGTGTGTTCTTCATCAGGACTGACCCTTCCAAAGCCATCACCCCTG
ACAACATCCACCAGGAGGTGAGTTTTAACATGTTAGATGCGGCAGATGGAGGCCTGCTCAACAGTGTGAGACGTTTGCTGTCGGACATCT
TCATTCCTGCTCTCAGAGCCACGAGCCATGGCTGGGGCGAGCTCGAGGGCCTTCAGGACGCAGCTAACATTCGCCAGGAGTTCTTGAGCT
CCCTGGAAGGCTTTGTGAACGTCCTGTCGGGTGCACAGGAGAGTCTGAAGGAGAAGGTGAACCTTCGAAAGTGTGACATACTTGAACTGA
AAACCCTAAAGGAACCTACGGACTACTTGACTCTAGCAAATAACCCTGAGACTTTGGGAAAAATAGAGGATTGCATGAAAGTATGGATCA
AACAGACAGAACAGGTTCTTGCTGAAAACAATCAGCTGCTGAAGGAAGCGGATGACGTTGGGCCACGAGCGGAGCTGGAGCACTGGAAAA
AAAGACTCTCCAAGTTTAACTACCTTTTGGAACAATTGAAAAGCCCGGATGTGAAGGCTGTGCTGGCAGTGCTTGCGGCGGCCAAGTCGA
AACTGCTGAAGACTTGGCGGGAGATGGATATTCGAATCACTGATGCAACTAATGAAGCAAAGGACAATGTGAAATACTTGTATACACTTG
AAAAATGTTGTGACCCTTTGTACAGCAGTGATCCCCTATCCATGATGGATGCTATTCCTACACTTATAAATGCAATTAAAATGATCTATA
GTATCTCTCATTACTATAATACCTCTGAGAAGATCACATCTCTGTTTGTAAAGGTGACAAATCAGATTATATCTGCATGTAAAGCCTATA
TTACCAATAATGGAACCGCTTCCATCTGGAACCAGCCACAGGATGTTGTTGAAGAAAAAATACTATCTGCGATTAAACTGAAACAGGAAT
ACCAGCTCTGCTTTCACAAGACAAAACAAAAGCTTAAACAAAATCCAAATGCAAAACAATTTGATTTTAGCGAGATGTATATTTTTGGAA
AATTCGAAACTTTTCACCGACGCCTTGCCAAGATAATAGACATCTTTACAACCCTCAAGACGTATTCAGTCCTGCAAGATTCCACAATTG
AAGGGCTGGAAGACATGGCCACTAAATACCAGGGCATTGTGGCAACCATAAAGAAAAAGGAATACAATTTCCTAGACCAGCGGAAAATGG
ATTTTGACCAAGATTACGAAGAGTTTTGCAAGCAGACTAATGACCTTCATAACGAGTTGCGGAAGTTCATGGATGTTACATTTGCAAAGA
TTCAAAACACAAATCAAGCTCTAAGAATGTTGAAGAAATTTGAAAGATTGAATATACCTAATCTTGGTATTGATGACAAATATCAACTTA
TCCTTGAGAACTATGGGGCTGACATTGATATGATTTCAAAGCTGTATACAAAGCAGAAATACGATCCTCCTCTGGCTCGAAACCAGCCTC
CCATCGCTGGAAAGATTTTGTGGGCCCGCCAGCTCTTCCATAGGATTCAGCAGCCCATGCAGCTTTTCCAGCAGCACCCAGCTGTGCTAA
GCACGGCAGAAGCCAAACCTATAATTCGCAGTTACAACAGGATGGCCAAGGTCCTCCTGGAGTTTGAGGTCCTCTTCCACAGGGCGTGGC
TTCGGCAAATTGAAGAAATTCATGTAGGTCTTGAGGCTTCATTATTGGTGAAGGCTCCAGGCACAGGGGAATTGTTTGTAAACTTTGACC
CTCAGATATTAATCTTATTTAGAGAAACAGAGTGCATGGCCCAGATGGGTCTGGAAGTCTCTCCACTGGCAACTTCCCTCTTCCAGAAAC
GAGATAGATACAAAAGGAACTTCAGTAACATGAAGATGATGCTAGCTGAATATCAGAGAGTGAAGTCAAAAATACCTGCTGCCATTGAGC
AATTGATTGTCCCTCACTTGGCCAAAGTGGATGAAGCTCTCCAACCTGGCTTGGCTGCACTGACCTGGACATCACTGAATATTGAGGCTT
ATTTAGAAAACACTTTTGCAAAGATCAAGGACCTGGAGTTGCTGCTTGACAGGGTCAATGATTTGATTGAGTTCCGCATTGATGCCATTC
TAGAAGAAATGAGCAGCACGCCTCTTTGTCAGCTTCCCCAGGAGGAGCCACTAACCTGTGAAGAGTTTCTCCAAATGACAAAGGATCTTT
GTGTAAATGGTGCACAAATACTACATTTTAAAAGCTCATTAGTGGAGGAGGCAGTCAATGAGCTTGTAAATATGTTGCTGGATGTGGAAG
TTTTATCTGAAGAAGAAAGTGAAAAAATATCCAATGAGAATAGTGTTAATTACAAAAATGAAAGTTCAGCAAAAAGAGAAGAAGGAAATT
TTGACACCTTGACATCATCTATTAATGCCAGGGCCAATGCCCTGCTTTTGACGACAGTCACGAGGAAAAAGAAAGAAACTGAGATGTTAG
GGGAAGAAGCCCGCGAGTTACTCTCTCATTTCAACCATCAGAACATGGATGCTCTTCTGAAAGTTACAAGGAATACACTAGAGGCCATTC
GCAAACGTATTCATTCCTCTCACACAATTAACTTCCGGGACAGTAACAGTGCCTCTAACATGAAGCAGAACAGTTTGCCCATTTTCCGGG
CAAGCGTCACTCTGGCCATTCCCAACATCGTCATGGCCCCTGCCCTGGAAGATGTACAGCAGACCCTGAACAAAGCCGTGGAGTGCATCA
TCAGTGTCCCTAAGGGGGTCAGACAGTGGAGCAGTGAACTGTTGTCCAAGAAAAAGATACAAGAAAGAAAAATGGCTGCTTTGCAGAGTA
ATGAAGACAGTGATTCTGATGTTGAAATGGGAGAAAATGAACTTCAAGATACCTTGGAGATAGCATCTGTAAATTTACCCATTCCCGTGC
AAACCAAGAACTATTATAAGAATGTTTCTGAAAACAAAGAGATTGTAAAATTAGTTTCTGTGCTTAGCACAATTATCAACTCCACCAAAA
AGGAAGTTATTACATCCATGGATTGCTTCAAACGCTACAATCACATTTGGCAAAAGGGAAAAGAAGAAGCCATTAAGACATTTATTACAC
AGAGCCCCTTGCTTTCTGAATTTGAGTCCCAGATTCTCTATTTCCAAAACCTAGAGCAGGAAATTAATGCTGAGCCTGAATATGTCTGTG
TGGGTTCCATTGCTCTGTACACAGCTGACTTGAAGTTCGCCCTGACTGCTGAGACAAAGGCCTGGATGGTTGTCATTGGACGCCACTGTA
ACAAAAAATACCGGAGTGAGATGGAAAACATTTTTATGCTTATTGAAGAATTCAATAAGAAACTAAATCGTCCAATTAAGGACCTAGATG
ATATTCGGATTGCAATGGCAGCGCTGAAAGAAATAAGGGAGGAGCAAATCTCCATTGACTTTCAAGTAGGACCTATTGAGGAATCTTATG
CCCTGCTTAACAGATATGGACTTCTGATAGCAAGGGAAGAGATAGACAAAGTTGATACACTGCACTATGCTTGGGAGAAGCTGCTGGCAC
GTGCTGGCGAAGTCCAGAATAAATTAGTCTCACTGCAGCCCAGTTTCAAGAAAGAGCTTATTAGTGCTGTGGAGGTATTCCTCCAAGATT
GTCACCAGTTTTATCTGGACTATGATTTGAATGGTCCAATGGCTAGCGGCTTGAAGCCCCAGGAAGCCAGTGACAGGCTTATCATGTTTC
AGAATCAATTTGATAATATCTATCGGAAATACATCACATATACTGGAGGAGAGGAGCTTTTTGGCCTGCCAGCTACACAGTATCCTCAGC
TTCTTGAAATAAAGAAGCAACTAAATCTTCTACAGAAAATATATACTCTGTACAACAGTGTCATAGAAACTGTAAATAGCTATTATGATA
TTCTTTGGTCAGAGGTGAATATTGAAAAAATTAACAATGAACTCTTAGAATTCCAGAACAGATGTCGAAAGCTTCCCCGGGCCTTGAAGG
ACTGGCAGGCTTTTTTGGACCTGAAGAAGATCATTGATGATTTCAGCGAGTGTTGCCCGCTGCTGGAATACATGGCCAGTAAAGCCATGA
TGGAGCGGCACTGGGAAAGGATAACCACCCTCACCGGGCACAGTCTGGATGTGGGGAATGAAAGCTTTAAGTTAAGAAATATCATGGAGG
CACCTCTTCTGAAATATAAAGAGGAAATAGAGGACATCTGTATCAGTGCGGTGAAAGAGAGAGACATTGAGCAAAAGCTGAAGCAAGTGA
TTAATGAATGGGACAATAAAACATTCACCTTCGGCAGCTTTAAAACCCGTGGAGAGCTCCTCTTGAGAGGAGACAGTACCTCGGAAATCA
TCGCCAACATGGAGGACAGCTTGATGTTGCTGGGATCCCTACTGAGCAACAGGTACAATATGCCATTCAAAGCCCAGATTCAAAAATGGG
TGCAGTACCTTTCCAACTCAACAGACATCATCGAGAGCTGGATGACGGTGCAAAACCTGTGGATTTATTTAGAAGCTGTCTTTGTGGGAG
GAGACATTGCCAAGCAGCTGCCCAAGGAAGCCAAGCGGTTTTCTAACATAGATAAATCTTGGGTGAAGATCATGACTCGGGCACATGAAG
TGCCCAGTGTAGTCCAGTGCTGTGTTGGAGATGAGACCCTGGGGCAGCTGTTACCACACTTGCTGGACCAGTTGGAAATATGCCAGAAAT
CCCTTACTGGGTACTTGGAGAAAAAACGACTGTGCTTTCCTCGGTTTTTCTTCGTCTCAGATCCTGCCCTTCTAGAGATTCTGGGGCAGG
CGTCGGACTCCCACACTATACAGGCCCATTTGCTGAATGTGTTTGACAACATTAAATCTGTCAAGTTCCACGAAAAGATCTATGATCGAA
TTCTGTCAATTTCCTCTCAAGAGGGTGAGACGATTGAATTGGATAAACCTGTCATGGCAGAGGGCAATGTGGAAGTTTGGCTTAATTCTC
TTTTGGAAGAATCTCAGTCCTCATTGCATCTTGTGATTCGCCAGGCAGCCGCAAATATTCAAGAAACAGGTTTCCAACTAACTGAATTTC
TTTCATCCTTCCCTGCTCAGGTTGGATTATTAGGAATTCAGATGATATGGACACGGGATTCAGAAGAAGCCCTTAGAAATGCCAAGTTTG
ATAAAAAAATCATGCAGAAAACTAATCAGGCTTTCCTGGAGCTACTCAATACATTGATAGACGTCACCACGAGGGATCTGAGTTCCACGG
AACGAGTGAAATACGAGACTCTGATTACTATTCATGTGCACCAAAGGGATATCTTTGATGACCTGTGTCATATGCATATCAAGAGTCCCA
TGGACTTTGAGTGGCTGAAACAGTGCAGATTTTACTTTAACGAAGATTCTGACAAGATGATGATTCACATCACAGATGTGGCGTTCATAT
ACCAGAATGAATTTTTAGGCTGCACTGACAGGCTTGTAATAACTCCACTTACAGACAGATGTTACATCACGCTGGCTCAAGCTCTGGGAA
TGAGCATGGGGGGAGCCCCTGCTGGACCTGCAGGCACAGGCAAAACAGAAACCACTAAAGACATGGGACGATGCCTCGGGAAATACGTCG
TGGTTTTCAATTGTTCAGACCAGATGGATTTCCGAGGACTTGGACGGATTTTTAAGGGACTGGCACAGTCTGGATCCTGGGGTTGTTTTG
ATGAATTTAACCGTATTGATCTACCAGTTCTCTCGGTTGCAGCCCAGCAAATTTCCATTATTCTGACATGTAAAAAGGAGCACAAAAAGT
CTTTTATCTTTACTGATGGAGATAATGTGACTATGAACCCTGAATTTGGGCTTTTCTTAACCATGAATCCTGGCTATGCCGGACGGCAGG
AACTCCCTGAAAACTTGAAGATTAATTTCCGCTCAGTGGCCATGATGGTGCCTGACCGTCAGATTATCATAAGGGTGAAGTTGGCTAGTT
GTGGCTTCATTGACAACGTTGTTTTGGCCAGGAAGTTTTTCACGCTCTACAAACTGTGTGAGGAGCAGCTTTCTAAGCAGGTTCATTATG
ACTTTGGCCTGCGTAACATTCTGTCAGTTCTTCGGACCTTGGGAGCAGCAAAAAGAGCCAATCCAATGGATACGGAGTCCACGATTGTCA
TGCGTGTACTACGGGACATGAATCTTTCTAAACTGATTGATGAGGATGAACCCTTGTTTTTGAGTTTGATTGAAGATCTCTTTCCAAATA
TTCTTCTGGACAAGGCAGGTTACCCTGAACTGGAAGCAGCAATTAGTAGACAGGTTGAAGAAGCTGGTTTAATCAACCATCCTCCTTGGA
AACTGAAGGTCATCCAGCTATTCGAAACGCAGAGAGTGCGACATGGGATGATGACTCTGGGGCCCAGTGGGGCTGGGAAGACCACCTGCA
TCCACACCTTGATGAGAGCCATGACAGATTGTGGAAAACCACATCGGGAAATGAGGATGAATCCCAAAGCGATTACTGCCCCACAGATGT
TTGGTCGGCTGGACGTTGCCACAAATGACTGGACTGATGGGATATTTTCTACGCTTTGGAGGAAAACATTAAGAGCAAAGAAAGGGGAAC
ATATCTGGATAATTCTTGATGGTCCAGTAGATGCCATCTGGATTGAAAATCTGAATTCTGTTTTGGATGATAACAAAACTCTAACCCTTG
CCAATGGTGATCGGATTCCCATGGCTCCAAACTGCAAGATCATTTTCGAGCCTCATAACATTGACAATGCTTCTCCTGCCACCGTCTCAA
GAAATGGAATGGTTTTCATGAGCTCTTCTATCCTTGATTGGAGTCCTATTCTTGAGGGTTTTCTTAAGAAACGCTCACCTCAAGAAGCAG
AAATTCTTCGTCAGCTGTACACCGAGTCTTTCCCAGACTTGTATCGCTTCTGTATCCAGAACTTAGAATACAAGATGGAGGTGCTGGAGG
CCTTTGTCATCACACAGAGCATTAACATGCTTCAAGGCCTGATTCCTCTGAAGGAGCAAGGCGGGGAGGTGAGCCAGGCTCACCTGGGGC
GGCTGTTCGTGTTCGCGCTGCTGTGGAGCGCGGGGGCGGCGCTGGAGCTGGACGGACGGCGCCGCCTGGAGCTCTGGCTGCGCTCTCGGC
CCACAGGGACGCTGGAGCTGCCGCCGCCAGCGGGGCCCGGGGACACCGCCTTCGACTACTATGTGGCGCCCGATGGTACATGGACGCACT
GGAACACGCGTACCCAGGAATACCTGTATCCGTCTGATACCACCCCAGAGTATGGTTCTATTCTGGTGCCAAATGTTGACAATGTGAGGA
CTGACTTTCTAATTCAAACCATTGCTAAACAGGGCAAGGCTGTGCTATTAATTGGTGAACAAGGAACAGCCAAAACAGTAATAATTAAAG
GATTTATGTCAAAATATGATCCTGAATGTCACATGATCAAGAGTCTGAATTTTTCTTCTGCAACCACCCCACTGATGTTCCAGAGGACGA
TAGAGAGCTATGTGGATAAACGAATGGGTACAACATATGGCCCTCCTGCGGGAAAGAAGATGACTGTTTTTATTGATGATGTGAATATGC
CAATAATCAATGAGTGGGGAGATCAGGTTACGAATGAGATAGTGCGACAGCTGATGGAACAAAATGGATTCTATAATCTAGAGAAGCCTG
GGGAGTTCACCAGCATCGTGGACATCCAGTTTTTGGCAGCCATGATCCATCCTGGTGGTGGACGCAATGACATACCCCAAAGACTCAAGA
GGCAGTTCTCTATATTTAATTGCACGTTGCCCTCTGAAGCTTCTGTGGACAAGATCTTTGGTGTGATTGGGGTAGGCCACTACTGTACTC
AGAGGGGTTTCTCAGAAGAAGTGAGAGATTCTGTGACAAAATTGGTGCCTCTGACACGCCGACTATGGCAGATGACCAAGATTAAAATGC
TTCCTACCCCTGCAAAATTCCATTATGTGTTTAACCTACGAGATCTTTCTCGGGTCTGGCAGGGAATGCTGAACACTACTTCAGAGGTCA
TCAAGGAACCAAATGATCTGTTAAAGCTGTGGAAGCATGAGTGTAAACGTGTTATAGCTGACCGTTTCACAGTGTCCAGTGATGTGACCT
GGTTTGATAAGGCTTTAGTAAGTTTGGTAGAGGAGGAGTTTGGTGAAGAGAAAAAACTCTTGGTGGATTGTGGAATTGACACATATTTTG
TGGATTTCTTGAGAGATGCACCTGAAGCTGCAGGTGAAACATCTGAAGAGGCTGATGCTGAAACACCTAAAATTTATGAGCCAATTGAAT
CTTTTAGTCACCTAAAAGAGCGTCTGAATATGTTCCTGCAGCTCTATAATGAGAGCATCCGTGGCGCCGGCATGGACATGGTGTTCTTTG
CAGATGCCATGGTTCACTTAGTCAAGATCTCTCGTGTCATTCGTACTCCTCAGGGAAATGCCCTCCTGGTCGGGGTGGGCGGATCAGGAA
AGCAGAGCCTGACGAGGTTGGCTTCATTCATTGCTGGCTACGTTTCCTTCCAGATCACTCTGACGAGATCCTACAACACATCAAATCTGA
TGGAAGATCTGAAGGTTTTGTATCGAACAGCTGGTCAGCAAGGCAAAGGAATCACTTTTATTTTCACAGACAATGAGATTAAAGATGAGT
CATTTTTGGAATATATGAACAATGTTTTATCATCAGGTGAGGTCTCTAACCTATTTGCTCGAGATGAAATTGATGAAATTAATAGCGACC
TGGCATCAGTCATGAAAAAAGAATTCCCCAGGTGCCTTCCTACCAATGAGAACCTGCACGACTACTTCATGAGTCGGGTCCGACAGAACC
TTCATATTGTGCTCTGCTTCTCGCCAGTGGGGGAGAAATTTCGAAACAGAGCTTTGAAGTTCCCTGCCCTAATTTCAGGATGCACAATTG
ACTGGTTCAGCCGATGGCCCAAAGATGCTTTAGTTGCTGTGTCTGAACACTTCCTCACTTCCTATGATATTGACTGCAGTTTGGAAATCA
AGAAGGAGGTGGTCCAATGCATGGGCTCCTTCCAGGATGGGGTGGCTGAGAAGTGTGTTGATTATTTTCAGAGATTCCGACGTTCTACCC
ACGTGACGCCCAAATCATACCTCTCCTTTATTCAGGGCTATAAGTTCATATATGGAGAAAAGCATGTGGAGGTGCGGACCCTGGCCAACA
GAATGAATACTGGATTGGAAAAGCTCAAAGAAGCTTCAGAGTCTGTTGCAGCCTTGAGTAAAGAACTGGAAGCGAAAGAAAAGGAGCTAC
AAGTGGCCAACGATAAAGCCGACATGGTCTTAAAAGAAGTGACAATGAAAGCACAGGCTGCTGAAAAGGTCAAGGCTGAGGTACAGAAGG
TGAAGGACAGGGCCCAGGCCATTGTGGACAGCATCTCTAAAGACAAAGCCATTGCTGAAGAAAAACTGGAAGCAGCAAAACCAGCTTTAG
AAGAGGCAGAAGCTGCATTGCAGACCATCAGGCCTTCGGACATCGCCACTGTTCGCACGTTGGGCCGCCCCCCTCACCTCATCATGCGGA
TCATGGATTGCGTACTGCTGCTGTTTCAAAGGAAAGTCAGTGCTGTGAAAATTGACCTGGAAAAAAGCTGTACCATGCCCTCCTGGCAGG
AATCCTTAAAATTGATGACTGCAGGGAACTTTTTACAGAACTTACAGCAATTCCCAAAAGACACAATCAATGAAGAGGTGATAGAATTTT
TGAGTCCTTACTTTGAAATGCCTGACTATAACATCGAAACTGCTAAACGCGTATGTGGAAATGTAGCTGGTCTTTGTTCCTGGACGAAAG
CTATGGCTTCCTTCTTTTCTATAAACAAAGAAGTACTGCCTCTGAAGGCCAACTTGGTGGTGCAAGAGAATCGCCATCTCCTGGCCATGC
AGGATCTGCAGAAAGCCCAGGCCGAGTTGGATGACAAGCAGGCGGAACTTGACGTGGTGCAGGCTGAGTATGAACAGGCCATGACTGAAA
AGCAGACCTTGCTTGAAGATGCAGAGCGATGCAGACACAAGATGCAGACAGCTTCCACGCTCATCAGTGGCTTGGCAGGTGAAAAAGAAA
GATGGACAGAGCAAAGCCAAGAGTTTGCTGCACAAACTAAAAGACTTGTAGGGGATGTACTGTTGGCTACAGCTTTTCTATCTTATTCTG
GTCCATTTAACCAAGAGTTTCGTGATCTTCTGTTAAATGACTGGCGGAAGGAAATGAAAGCCCGGAAAATTCCATTTGGAAAGAACCTAA
ATCTCAGTGAGATGTTGATTGATGCTCCTACTATTAGTGAATGGAACCTCCAAGGTCTGCCAAATGATGACTTGTCCATTCAAAATGGAA
TTATTGTCACGAAGGCATCTCGTTACCCTTTGTTAATTGATCCACAGACTCAAGGCAAGATCTGGATTAAAAATAAAGAAAGCCGAAATG
AACTCCAGATCACGTCTTTAAATCACAAGTACTTCAGAAACCACCTGGAAGACAGCCTTTCTCTTGGAAGGCCTTTGCTTATTGAAGATG
TTGGAGAGGAACTAGATCCAGCACTAGATAATGTTTTGGAAAGAAACTTCATTAAAACTGGGTCTACCTTTAAGGTGAAAGTTGGTGACA
AGGAAGTAGATGTGTTGGATGGCTTTAGACTCTACATTACCACCAAATTGCCTAACCCAGCCTACACCCCTGAGATAAGTGCCCGTACCT
CCATCATTGACTTCACTGTCACCATGAAAGGTCTAGAAGATCAGTTACTGGGGAGGGTCATTCTCACAGAGAAGCAGGAATTGGAGAAAG
AAAGAACTCATCTGATGGAAGATGTAACTGCAAACAAAAGAAGGATGAAGGAACTAGAAGATAACTTGCTTTACCGCCTGACAAGTACCC
AGGGGTCCCTGGTAGAAGATGAAAGTCTCATTGTCGTGCTGAGTAACACAAAAAGGACAGCCGAGGAGGTGACACAGAAGCTAGAAATTT
CTGCTGAGACAGAAGTTCAAATTAACTCAGCCCGGGAGGAATACAGACCTGTGGCTACGCGGGGCAGCATCCTCTACTTCCTCATTACTG
AGATGCGCTTGGTTAATGAGATGTATCAGACTTCGCTTCGCCAGTTTCTGGGCTTATTTGACCTTTCCTTAGCCAGGTCTGTCAAGAGCC
CGATTACAAGCAAGAGGATTGCTAATATCATCGAGCACATGACCTACGAGGTTTATAAGTATGCTGCCCGAGGGCTGTACGAGGAGCACA
AATTCCTGTTCACCTTGTTGCTTACCCTAAAGATTGACATCCAGAGGAACCGAGTCAAGCATGAAGAGTTTCTCACTCTTATTAAAGGAG
GTGCCTCATTAGACCTTAAAGCTTGTCCTCCAAAACCATCAAAATGGATCCTGGACATAACATGGCTGAATTTGGTGGAACTTAGCAAAC
TCAGACAGTTTTCAGATGTCCTTGACCAGATATCGAGAAATGAGAAAATGTGGAAAATTTGGTTTGATAAGGAAAACCCGGAGGAGGAAC
CTCTTCCAAATGCCTATGATAAATCTCTTGACTGCTTCAGACGTCTTCTCCTTATTAGATCCTGGTGTCCTGACAGAACCATCGCCCAGG
CCCGCAAGTACATCGTGGACTCCATGGGAGAAAAATATGCCGAAGGTGTTATTTTAGACTTGGAGAAGACGTGGGAGGAATCTGATCCAC
GGACGCCACTCATCTGTCTCCTGTCTATGGGCTCAGACCCCACAGATTCCATCATTGCCTTGGGGAAGAGATTAAAAATAGAAACCCGTT
ATGTGTCCATGGGCCAGGGCCAGGAAGTCCATGCTCGGAAGCTCTTGCAGCAGACCATGGCGAACGGAGGATGGGCACTTCTGCAGAACT
GCCATCTGGGACTTGATTTCATGGATGAGCTGATGGACATAATCATAGAAACTGAGCTTGTACATGATGCGTTCCGCCTCTGGATGACCA
CCGAGGCTCATAAGCAGTTTCCCATTACACTCCTTCAGATGTCCATTAAATTTGCCAACGATCCTCCACAAGGACTCCGGGCAGGACTGA
AAAGAACATATAGTGGTGTCAGCCAAGACCTGCTGGACGTGAGCTCTGGGTCCCAGTGGAAGCCCATGCTGTACGCAGTGGCTTTCCTGC
ACTCCACTGTCCAGGAGAGGCGCAAGTTCGGTGCCCTGGGGTGGAATATCCCCTACGAATTTAACCAAGCGGACTTTAATGCCACTGTGC
AGTTCATCCAAAACCACTTGGATGACATGGATGTCAAAAAGGGTGTCTCCTGGACCACCATCCGCTACATGATAGGAGAGATTCAATATG
GAGGCAGAGTCACTGACGACTATGATAAGAGATTGTTGAACACATTTGCTAAGGTTTGGTTCAGTGAAAATATGTTTGGACCAGATTTCA
GTTTTTACCAAGGATACAATATTCCAAAATGCAGCACAGTGGATAACTATCTTCAGTATATCCAGAGTTTGCCTGCCTATGACAGCCCTG
AGGTGTTTGGGCTGCACCCCAATGCTGACATCACCTACCAGAGCAAGCTGGCCAAGGACGTGCTGGACACCATCCTAGGCATCCAACCCA
AGGACACCTCTGGTGGAGGGGATGAGACCCGGGAGGCGGTGGTGGCCCGGCTGGCTGATGATATGCTGGAGAAGCTGCCCCCAGACTATG
TCCCCTTTGAAGTAAAAGAGAGGCTGCAGAAGATGGGGCCATTCCAGCCTATGAACATTTTCCTCAGGCAGGAAATAGACAGAATGCAAA
GGGTACTCAGCCTTGTCCGCAGCACCCTCACTGAGCTGAAACTTGCTATTGATGGCACCATCATCATGAGCGAAAATCTGCGAGATGCAT
TGGATTGCATGTTTGATGCTAGAATCCCTGCTTGGTGGAAAAAAGCTTCTTGGATTTCTAGTACACTGGGTTTCTGGTTTACTGAACTTA
TAGAAAGAAACAGCCAGTTTACCTCGTGGGTTTTCAATGGCCGACCTCACTGCTTTTGGATGACGGGTTTTTTTAACCCCCAGGGATTTT
TAACTGCAATGCGACAGGAAATAACTCGGGCCAACAAAGGCTGGGCTCTGGACAATATGGTGCTTTGCAATGAAGTCACCAAATGGATGA
AGGACGACATTTCTGCCCCTCCCACAGAGGGTGTCTATGTCTATGGCTTATATCTTGAAGGTGCTGGCTGGGACAAGAGGAACATGAAAC
TCATTGAATCAAAGCCAAAAGTGCTCTTTGAGTTGATGCCTGTCATAAGGATTTATGCAGAAAACAATACTTTACGAGATCCTCGGTTTT
ACTCCTGTCCCATCTATAAGAAGCCAGTTCGAACGGACTTGAACTACATTGCCGCTGTGGATCTCAGGACAGCCCAGACCCCTGAACACT
GGGTGCTCCGTGGGGTTGCCCTTCTGTGTGATGTCAAGTAACATGTGGGGAGTGTCCCCACCCAATGCTTTGGAAAATGCAAGATCTAAA
TTATTGTAACCTTTATTTCTGTATGACTGCTGGACAGTGTATGTTAGGTCGTTTATGCAATTAATGAGCTGCATAGGTTTTCCCCACTCC
TTAATTGGATGCTTATATTTTACTTGTTTCATCATTAGTGACCAATGTCTGAGTTTGTTGAAAATGTTATTTAGTGATATAAAAGTAAAT
TTACAGCATCCTAATGAAGTGTGGCCCTCAAATCCACAGTAGTATATTTTCTTCTTACTTCGCTCCGAAGACTGACTAGGGTAAGCAGAC
AGTATTTCTCTGGGAGGAATTATTCTTCTGTTAACGTGGCCTGGTAACAGCCAAGTTCTTGAAGGTAACAGGGCAAGTCTGTGCTGATTT
TGCTTCTATTGCCTTTCGTATTTAGGTCAAGTTAAGAGACTTATTTTCAGGGTTTCAAGCAGCCAATTAAAAATACCTTTTAAAAAATAG
AAGGAAATAGAAGAATGGATTAAGAATGTAAATAGAAAATTTATGTAAACATAGAGAATAAACGTAGAACAATGCTTAAGCCTACTTATA
ATTAATAATGAAATACTAATTGATAATTCTTATAATAAAAATTAAAGCTAAAAGTAAATGATAGCATGCTCTCAGTAAAACTGATCCACT
CACAAATTGCTGGAGCAATGTAAATCAACCCAACCTTTTTGTAAAATGATTAAATACAGAAAGAGCCATAAAAATATTCACACCCTTGGA
TCTTTGTTTTCTCTACATCAAGGAAACAATTTAAAAGACTGAAAACAGTCTATATAAAATTGCATTTAATAACAGAAAAAAATGGAAAAA
TCATAAATATTCAATAGTCAGGCTATGGTTAAGGAAATTAAGAGATATTTGGCAACCATAAAAAACAATTTTGAAGATTCCATAATATGA
AATGGTAGACCCAGACTGTTAAGTGAAAGATTTAGTTTACAAAATATTGAGCACACTGTGATTATAACAGCAAATATATTTGCATGTGGA
CAAAGATTAGATGGCAAGATAGAAAAATAAGAACAGATGTGATAGCAAGAATTATAGTTGGCTTGAAAAAATGTGATGATCAGGAGAAAA
AATAAAAAAAGGGTAGAAATATTAGACGGTGCGTAGGGACTTTCTATGGACTTTTATTAATTAGGAAACATTATCAAAGGAACTTTTCAC
GTATTTTTCTTTAAATTCTGGTTAGATGTTATTAATAATTCTTCATCTAACCTACTGACTAGAAAATATAGTCAGTACTAAATTAGAATT
GTGGTTTATAAACTTTTGGTTAGCTCTGGATCTGTATAACTGCATTTTTTTGGATAAACAGTTTTTGGTAGGTGGATACCGGGAGACAAG
TGTGGGTCCCTCTCACTGGGCTTCATTCTGTGGACCAGGATCATTATTTCATGCTCATGATCATGAGAGTTAGGACTGAGTGGCTCCTGT
GACTCCCACCATCTTAGATGATACTGTTTTCTTGTGAGTTCTTTCTTTTGGTGTGGATTAGTATATCAGTTGATTTGTGTGAATTGTGGT

>94199_94199_2_TRIO-DNAH5_TRIO_chr5_14391099_ENST00000509967_DNAH5_chr5_13931353_ENST00000265104_length(amino acids)=5962AA_BP=1355
MAEGFRKNDEMKAMDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIK
PLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFETNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATH
MLSRLEELQDILAKKELPQDLEGARNMIEEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLH
STRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLV
ESGHYASQQIRQIASQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYS
EVSQDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDVIHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAF
LSKHTGVGKSLHRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTH
VKELWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTTLQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQS
QMEELFQERKIKLELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEV
QASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQRE
HEQFQHAIEKTHQSALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYKREED
WCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRNADVFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTM
RKRRLDQCQQYVVFERSAKQALEWIHDNGEFYLSTHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLIQLADGFCEKGHAHAAEIKK
CVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQLDIIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEKAYVR
DLRECMDTYLWEMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILE
HAGSYFDQRLKGEKEAKRALLDARHNYLFAIVASCLDLNKTEVEDAILEGNQIERIDQLFAVGGLRHLMFYYQDVEEAETGQLGSLGGVN
LVSGKIKKPKVFVTEGNDVALTGVCVFFIRTDPSKAITPDNIHQEVSFNMLDAADGGLLNSVRRLLSDIFIPALRATSHGWGELEGLQDA
ANIRQEFLSSLEGFVNVLSGAQESLKEKVNLRKCDILELKTLKEPTDYLTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLKEADDVG
PRAELEHWKKRLSKFNYLLEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYSSDPLSMMDAIPT
LINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYITNNGTASIWNQPQDVVEEKILSAIKLKQEYQLCFHKTKQKLKQNPNAKQF
DFSEMYIFGKFETFHRRLAKIIDIFTTLKTYSVLQDSTIEGLEDMATKYQGIVATIKKKEYNFLDQRKMDFDQDYEEFCKQTNDLHNELR
KFMDVTFAKIQNTNQALRMLKKFERLNIPNLGIDDKYQLILENYGADIDMISKLYTKQKYDPPLARNQPPIAGKILWARQLFHRIQQPMQ
LFQQHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLRQIEEIHVGLEASLLVKAPGTGELFVNFDPQILILFRETECMAQMGLEVS
PLATSLFQKRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLNIEAYLENTFAKIKDLELLLDRVND
LIEFRIDAILEEMSSTPLCQLPQEEPLTCEEFLQMTKDLCVNGAQILHFKSSLVEEAVNELVNMLLDVEVLSEEESEKISNENSVNYKNE
SSAKREEGNFDTLTSSINARANALLLTTVTRKKKETEMLGEEARELLSHFNHQNMDALLKVTRNTLEAIRKRIHSSHTINFRDSNSASNM
KQNSLPIFRASVTLAIPNIVMAPALEDVQQTLNKAVECIISVPKGVRQWSSELLSKKKIQERKMAALQSNEDSDSDVEMGENELQDTLEI
ASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVITSMDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILYFQNLEQE
INAEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEFNKKLNRPIKDLDDIRIAMAALKEIREEQISIDF
QVGPIEESYALLNRYGLLIAREEIDKVDTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMASGLKPQ
EASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNR
CRKLPRALKDWQAFLDLKKIIDDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISAVKER
DIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLW
IYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSD
PALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQ
ETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLITIHVHQRDIFDD
LCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKD
MGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLT
MNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRAN
PMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLG
PSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSV
LDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQN
LEYKMEVLEAFVITQSINMLQGLIPLKEQGGEVSQAHLGRLFVFALLWSAGAALELDGRRRLELWLRSRPTGTLELPPPAGPGDTAFDYY
VAPDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSA
TTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGG
RNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQ
GMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAE
TPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITL
TRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHD
YFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVD
YFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAA
EKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLE
KSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVV
QENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVL
LATAFLSYSGPFNQEFRDLLLNDWRKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKI
WIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPA
YTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTA
EEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKY
AARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIW
FDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIAL
GKRLKIETRYVSMGQGQEVHARKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELVHDAFRLWMTTEAHKQFPITLLQMSIKFAND
PPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPMLYAVAFLHSTVQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTI
RYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDV
LDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTI
IMSENLRDALDCMFDARIPAWWKKASWISSTLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMV
LCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIYAENNTLRDPRFYSCPIYKKPVRTDLNYIAAVD

--------------------------------------------------------------
>94199_94199_3_TRIO-DNAH5_TRIO_chr5_14391099_ENST00000537187_DNAH5_chr5_13931353_ENST00000265104_length(transcript)=19695nt_BP=4224nt
GCAGCCATGAGCGGCAGCAGCGGCGGAGCCGCCGCCCCCGCCGCGTCCTCCGGCCCCGCCGCGGCGGCCAGCGCGGCTGGCTCGGGCTGC
GGGGGCGGTGCCGGCGAGGGGGCAGAGGAGGCGGCCAAGGACCTGGCCGACATCGCGGCCTTCTTCCGATCCGGGTTTCGAAAAAACGAT
GAAATGAAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGGAGAGATAAACGTGGAGGTCCCATTTTA
ACGTTTCCGGCCCGCAGCAATCATGACAGAATACGACAGGAGGATCTCAGGAGACTCATTTCCTATCTAGCCTGTATTCCCAGCGAGGAG
GTCTGCAAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAGCCCCTTCTGAAGATCCTGCAGGAGTCC
TTCCCCTGCTGCATCCATGTGGCCCTGATCATCAAGCCAGACAACTTCTGGCAGAAACAGAGGACTAATTTTGGCAGTTCTAAATTTGAA
TTTGAGACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACTCCTGAGTTTGATGGCTGCCTGGAATAC
AACCACGAAGAATGGATTGAAATCAGAGTTGCTTTTGAAGACTACATTAGCAATGCCACCCACATGCTGTCTCGGCTGGAGGAACTTCAG
GACATCCTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAACATTCTCAGCTGAAGAAGAAGGTGATT
AAGGCCCCCATCGAGGACCTGGATTTGGAGGGACAGAAGCTGCTTCAGAGGATACAGAGCAGTGAAAGCTTTCCCAAAAAGAACTCAGGC
TCAGGCAATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCACTCGACACGGCAGCATCTGCACCAGATG
TGGCATGTGAGGAAGCTGAAGCTGGACCAGTGCTTCCAGCTGAGGCTGTTTGAACAGGATGCTGAGAAGATGTTTGACTGGATCACACAC
AACAAAGGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAGCTTCAGACGCAGCACAATCACTTTGCC
ATGAACTGTATGAACGTGTATGTAAATATAAACCGCATCATGTCGGTGGCCAATCGTCTGGTGGAGTCTGGCCACTATGCCTCGCAGCAG
ATCAGGCAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAGCGGAGCACCTTGCTGGACATGTCCTCC
ATTTTCCACCAGAAGGCCGAAAAGTATATGAGCAACGTGGATTCATGGTGTAAAGCTTGCGGTGAGGTAGACCTTCCCTCAGAGCTGCAG
GACCTAGAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCTGAGGTCAGCCAAGATGGGAAGTCGCTC
CTTGACAAGCTCCAGCGGCCCTTGACTCCCGGCAGCTCCGATTCCCTGACAGCCTCTGCCAACTACTCCAAGGCCGTGCACCATGTCCTG
GATGTCATCCACGAGGTGCTGCACCACCAGCGGCAGCTGGAGAACATCTGGCAACACCGCAAGGTCCGGCTGCATCAGAGGCTGCAGCTG
TGTGTTTTCCAGCAGGACGTTCAGCAGGTGCTAGACTGGATCGAGAACCACGGAGAAGCATTTCTGAGCAAACATACAGGTGTGGGGAAA
TCTCTTCATCGGGCCAGAGCATTGCAGAAACGTCATGAAGATTTTGAAGAAGTGGCACAGAACACATACACCAATGCGGATAAATTACTG
GAAGCAGCAGAACAGCTGGCTCAGACTGGGGAATGTGACCCCGAAGAGATTTATCAGGCTGCCCATCAGCTGGAAGACCGGATTCAAGAT
TTCGTTCGGCGTGTTGAGCAGCGAAAGATCCTACTGGACATGTCAGTGTCCTTTCACACCCATGTGAAAGAGCTGTGGACGTGGCTGGAG
GAGCTGCAGAAGGAGCTGCTGGACGACGTGTATGCCGAGTCGGTGGAGGCCGTGCAGGACCTCATCAAGCGCTTTGGCCAGCAGCAGCAG
ACCACCCTGCAGGTGACTGTCAACGTGATCAAGGAAGGGGAGGACCTCATCCAGCAGCTCAGGGACTCTGCCATCTCCAGTAACAAGACC
CCCCACAACAGCTCCATCAACCACATTGAGACGGTGCTGCAGCAGCTGGACGAGGCGCAGTCGCAGATGGAGGAGCTCTTCCAGGAGCGC
AAGATCAAGCTGGAGCTCTTCCTGCAGCTGCGCATCTTCGAGAGGGACGCCATCGACATTATCTCAGACCTCGAGTCTTGGAATGATGAG
CTTTCTCAGCAAATGAATGACTTCGACACAGAAGATCTCACGATTGCAGAGCAGCGCCTCCAGCACCATGCAGACAAAGCCTTGACCATG
AACAACTTGACTTTTGACGTCATCCACCAAGGGCAAGATCTTCTGCAGTATGTCAATGAGGTCCAGGCCTCTGGTGTGGAGCTGCTGTGT
GATAGAGATGTAGACATGGCAACTCGGGTCCAGGACCTGCTGGAGTTTCTTCATGAAAAACAGCAGGAATTGGATTTAGCCGCAGAGCAG
CATCGGAAACACCTGGAGCAGTGCGTGCAGCTGCGCCACCTGCAGGCAGAAGTGAAACAGGTGCTGGGTTGGATCCGCAACGGAGAGTCC
ATGTTAAATGCCGGACTTATCACAGCCAGCTCGTTACAAGAGGCAGAGCAGCTCCAGCGAGAGCACGAGCAGTTCCAGCATGCCATTGAG
AAAACACATCAGAGCGCGCTGCAGGTGCAGCAGAAGGCAGAAGCCATGCTACAGGCCAACCACTACGACATGGACATGATCCGGGACTGC
GCCGAGAAGGTGGCGTCTCACTGGCAACAGCTCATGCTCAAGATGGAAGATCGCCTCAAGCTCGTCAACGCCTCTGTCGCTTTCTACAAA
ACCTCAGAGCAGGTCTGCAGCGTCCTCGAGAGCCTGGAACAGGAGTACAAGAGAGAAGAAGACTGGTGTGGCGGGGCGGATAAGCTGGGC
CCAAACTCTGAGACGGACCACGTGACGCCCATGATCAGCAAGCACCTGGAGCAGAAGGAGGCATTCCTGAAGGCTTGCACCCTTGCTCGG
AGGAATGCAGACGTCTTCCTGAAATACCTGCACAGGAACAGCGTGAACATGCCAGGAATGGTGACGCACATCAAAGCTCCTGAACAGCAA
GTGAAAAATATCTTGAATGAACTCTTCCAACGGGAGAACAGGGTATTGCATTACTGGACCATGAGGAAGAGACGGCTGGACCAGTGTCAG
CAGTACGTGGTCTTTGAGAGGAGTGCCAAGCAGGCTTTGGAATGGATCCATGACAATGGCGAGTTCTACCTTTCCACACACACCTCCACG
GGCTCCAGTATACAGCACACCCAGGAGCTCCTGAAAGAGCACGAGGAGTTCCAGATAACTGCAAAGCAAACCAAAGAGAGAGTGAAGCTA
TTGATACAGCTGGCTGATGGCTTTTGTGAAAAAGGGCATGCCCATGCGGCAGAGATAAAAAAATGTGTTACTGCTGTGGATAAGAGGTAC
AGAGATTTCTCTCTGCGGATGGAGAAGTACAGGACCTCTTTGGAAAAAGCCCTGGGGATTTCTTCAGATTCCAACAAATCGAGTAAAAGT
CTCCAGCTAGATATCATTCCAGCCAGTATCCCTGGCTCAGAGGTGAAACTTCGAGATGCTGCTCATGAACTTAATGAAGAGAAGCGGAAA
TCTGCCCGCAGGAAAGAGTTCATAATGGCTGAGCTCATTCAAACTGAAAAGGCTTATGTAAGAGACCTCCGGGAATGTATGGATACGTAC
CTGTGGGAAATGACCAGTGGCGTGGAAGAGATTCCACCTGGCATTGTAAACAAAGAACTCATCATCTTCGGAAACATGCAAGAAATCTAC
GAATTTCATAATAACATATTCCTAAAGGAGCTGGAAAAATATGAACAGTTGCCAGAGGATGTTGGACATTGTTTTGTTACTTGGGCAGAC
AAGTTTCAGATGTATGTCACATATTGCAAAAATAAGCCTGATTCTACTCAGCTGATATTGGAACATGCAGGGTCCTATTTTGACCAAAGA
CTGAAGGGAGAGAAGGAAGCCAAGCGGGCTCTTTTGGATGCGAGGCATAACTACTTATTTGCAATTGTGGCTTCCTGTTTGGACCTGAAC
AAAACCGAAGTGGAGGATGCCATTCTTGAAGGGAATCAGATTGAAAGAATTGATCAACTTTTTGCTGTTGGAGGTCTCCGACACCTCATG
TTTTACTATCAAGATGTGGAGGAAGCAGAAACAGGACAACTTGGCTCTCTAGGAGGGGTAAATCTTGTTTCTGGAAAGATTAAAAAACCT
AAGGTGTTCGTGACCGAGGGAAACGATGTGGCTCTTACTGGGGTATGTGTGTTCTTCATCAGGACTGACCCTTCCAAAGCCATCACCCCT
GACAACATCCACCAGGAGGTGAGTTTTAACATGTTAGATGCGGCAGATGGAGGCCTGCTCAACAGTGTGAGACGTTTGCTGTCGGACATC
TTCATTCCTGCTCTCAGAGCCACGAGCCATGGCTGGGGCGAGCTCGAGGGCCTTCAGGACGCAGCTAACATTCGCCAGGAGTTCTTGAGC
TCCCTGGAAGGCTTTGTGAACGTCCTGTCGGGTGCACAGGAGAGTCTGAAGGAGAAGGTGAACCTTCGAAAGTGTGACATACTTGAACTG
AAAACCCTAAAGGAACCTACGGACTACTTGACTCTAGCAAATAACCCTGAGACTTTGGGAAAAATAGAGGATTGCATGAAAGTATGGATC
AAACAGACAGAACAGGTTCTTGCTGAAAACAATCAGCTGCTGAAGGAAGCGGATGACGTTGGGCCACGAGCGGAGCTGGAGCACTGGAAA
AAAAGACTCTCCAAGTTTAACTACCTTTTGGAACAATTGAAAAGCCCGGATGTGAAGGCTGTGCTGGCAGTGCTTGCGGCGGCCAAGTCG
AAACTGCTGAAGACTTGGCGGGAGATGGATATTCGAATCACTGATGCAACTAATGAAGCAAAGGACAATGTGAAATACTTGTATACACTT
GAAAAATGTTGTGACCCTTTGTACAGCAGTGATCCCCTATCCATGATGGATGCTATTCCTACACTTATAAATGCAATTAAAATGATCTAT
AGTATCTCTCATTACTATAATACCTCTGAGAAGATCACATCTCTGTTTGTAAAGGTGACAAATCAGATTATATCTGCATGTAAAGCCTAT
ATTACCAATAATGGAACCGCTTCCATCTGGAACCAGCCACAGGATGTTGTTGAAGAAAAAATACTATCTGCGATTAAACTGAAACAGGAA
TACCAGCTCTGCTTTCACAAGACAAAACAAAAGCTTAAACAAAATCCAAATGCAAAACAATTTGATTTTAGCGAGATGTATATTTTTGGA
AAATTCGAAACTTTTCACCGACGCCTTGCCAAGATAATAGACATCTTTACAACCCTCAAGACGTATTCAGTCCTGCAAGATTCCACAATT
GAAGGGCTGGAAGACATGGCCACTAAATACCAGGGCATTGTGGCAACCATAAAGAAAAAGGAATACAATTTCCTAGACCAGCGGAAAATG
GATTTTGACCAAGATTACGAAGAGTTTTGCAAGCAGACTAATGACCTTCATAACGAGTTGCGGAAGTTCATGGATGTTACATTTGCAAAG
ATTCAAAACACAAATCAAGCTCTAAGAATGTTGAAGAAATTTGAAAGATTGAATATACCTAATCTTGGTATTGATGACAAATATCAACTT
ATCCTTGAGAACTATGGGGCTGACATTGATATGATTTCAAAGCTGTATACAAAGCAGAAATACGATCCTCCTCTGGCTCGAAACCAGCCT
CCCATCGCTGGAAAGATTTTGTGGGCCCGCCAGCTCTTCCATAGGATTCAGCAGCCCATGCAGCTTTTCCAGCAGCACCCAGCTGTGCTA
AGCACGGCAGAAGCCAAACCTATAATTCGCAGTTACAACAGGATGGCCAAGGTCCTCCTGGAGTTTGAGGTCCTCTTCCACAGGGCGTGG
CTTCGGCAAATTGAAGAAATTCATGTAGGTCTTGAGGCTTCATTATTGGTGAAGGCTCCAGGCACAGGGGAATTGTTTGTAAACTTTGAC
CCTCAGATATTAATCTTATTTAGAGAAACAGAGTGCATGGCCCAGATGGGTCTGGAAGTCTCTCCACTGGCAACTTCCCTCTTCCAGAAA
CGAGATAGATACAAAAGGAACTTCAGTAACATGAAGATGATGCTAGCTGAATATCAGAGAGTGAAGTCAAAAATACCTGCTGCCATTGAG
CAATTGATTGTCCCTCACTTGGCCAAAGTGGATGAAGCTCTCCAACCTGGCTTGGCTGCACTGACCTGGACATCACTGAATATTGAGGCT
TATTTAGAAAACACTTTTGCAAAGATCAAGGACCTGGAGTTGCTGCTTGACAGGGTCAATGATTTGATTGAGTTCCGCATTGATGCCATT
CTAGAAGAAATGAGCAGCACGCCTCTTTGTCAGCTTCCCCAGGAGGAGCCACTAACCTGTGAAGAGTTTCTCCAAATGACAAAGGATCTT
TGTGTAAATGGTGCACAAATACTACATTTTAAAAGCTCATTAGTGGAGGAGGCAGTCAATGAGCTTGTAAATATGTTGCTGGATGTGGAA
GTTTTATCTGAAGAAGAAAGTGAAAAAATATCCAATGAGAATAGTGTTAATTACAAAAATGAAAGTTCAGCAAAAAGAGAAGAAGGAAAT
TTTGACACCTTGACATCATCTATTAATGCCAGGGCCAATGCCCTGCTTTTGACGACAGTCACGAGGAAAAAGAAAGAAACTGAGATGTTA
GGGGAAGAAGCCCGCGAGTTACTCTCTCATTTCAACCATCAGAACATGGATGCTCTTCTGAAAGTTACAAGGAATACACTAGAGGCCATT
CGCAAACGTATTCATTCCTCTCACACAATTAACTTCCGGGACAGTAACAGTGCCTCTAACATGAAGCAGAACAGTTTGCCCATTTTCCGG
GCAAGCGTCACTCTGGCCATTCCCAACATCGTCATGGCCCCTGCCCTGGAAGATGTACAGCAGACCCTGAACAAAGCCGTGGAGTGCATC
ATCAGTGTCCCTAAGGGGGTCAGACAGTGGAGCAGTGAACTGTTGTCCAAGAAAAAGATACAAGAAAGAAAAATGGCTGCTTTGCAGAGT
AATGAAGACAGTGATTCTGATGTTGAAATGGGAGAAAATGAACTTCAAGATACCTTGGAGATAGCATCTGTAAATTTACCCATTCCCGTG
CAAACCAAGAACTATTATAAGAATGTTTCTGAAAACAAAGAGATTGTAAAATTAGTTTCTGTGCTTAGCACAATTATCAACTCCACCAAA
AAGGAAGTTATTACATCCATGGATTGCTTCAAACGCTACAATCACATTTGGCAAAAGGGAAAAGAAGAAGCCATTAAGACATTTATTACA
CAGAGCCCCTTGCTTTCTGAATTTGAGTCCCAGATTCTCTATTTCCAAAACCTAGAGCAGGAAATTAATGCTGAGCCTGAATATGTCTGT
GTGGGTTCCATTGCTCTGTACACAGCTGACTTGAAGTTCGCCCTGACTGCTGAGACAAAGGCCTGGATGGTTGTCATTGGACGCCACTGT
AACAAAAAATACCGGAGTGAGATGGAAAACATTTTTATGCTTATTGAAGAATTCAATAAGAAACTAAATCGTCCAATTAAGGACCTAGAT
GATATTCGGATTGCAATGGCAGCGCTGAAAGAAATAAGGGAGGAGCAAATCTCCATTGACTTTCAAGTAGGACCTATTGAGGAATCTTAT
GCCCTGCTTAACAGATATGGACTTCTGATAGCAAGGGAAGAGATAGACAAAGTTGATACACTGCACTATGCTTGGGAGAAGCTGCTGGCA
CGTGCTGGCGAAGTCCAGAATAAATTAGTCTCACTGCAGCCCAGTTTCAAGAAAGAGCTTATTAGTGCTGTGGAGGTATTCCTCCAAGAT
TGTCACCAGTTTTATCTGGACTATGATTTGAATGGTCCAATGGCTAGCGGCTTGAAGCCCCAGGAAGCCAGTGACAGGCTTATCATGTTT
CAGAATCAATTTGATAATATCTATCGGAAATACATCACATATACTGGAGGAGAGGAGCTTTTTGGCCTGCCAGCTACACAGTATCCTCAG
CTTCTTGAAATAAAGAAGCAACTAAATCTTCTACAGAAAATATATACTCTGTACAACAGTGTCATAGAAACTGTAAATAGCTATTATGAT
ATTCTTTGGTCAGAGGTGAATATTGAAAAAATTAACAATGAACTCTTAGAATTCCAGAACAGATGTCGAAAGCTTCCCCGGGCCTTGAAG
GACTGGCAGGCTTTTTTGGACCTGAAGAAGATCATTGATGATTTCAGCGAGTGTTGCCCGCTGCTGGAATACATGGCCAGTAAAGCCATG
ATGGAGCGGCACTGGGAAAGGATAACCACCCTCACCGGGCACAGTCTGGATGTGGGGAATGAAAGCTTTAAGTTAAGAAATATCATGGAG
GCACCTCTTCTGAAATATAAAGAGGAAATAGAGGACATCTGTATCAGTGCGGTGAAAGAGAGAGACATTGAGCAAAAGCTGAAGCAAGTG
ATTAATGAATGGGACAATAAAACATTCACCTTCGGCAGCTTTAAAACCCGTGGAGAGCTCCTCTTGAGAGGAGACAGTACCTCGGAAATC
ATCGCCAACATGGAGGACAGCTTGATGTTGCTGGGATCCCTACTGAGCAACAGGTACAATATGCCATTCAAAGCCCAGATTCAAAAATGG
GTGCAGTACCTTTCCAACTCAACAGACATCATCGAGAGCTGGATGACGGTGCAAAACCTGTGGATTTATTTAGAAGCTGTCTTTGTGGGA
GGAGACATTGCCAAGCAGCTGCCCAAGGAAGCCAAGCGGTTTTCTAACATAGATAAATCTTGGGTGAAGATCATGACTCGGGCACATGAA
GTGCCCAGTGTAGTCCAGTGCTGTGTTGGAGATGAGACCCTGGGGCAGCTGTTACCACACTTGCTGGACCAGTTGGAAATATGCCAGAAA
TCCCTTACTGGGTACTTGGAGAAAAAACGACTGTGCTTTCCTCGGTTTTTCTTCGTCTCAGATCCTGCCCTTCTAGAGATTCTGGGGCAG
GCGTCGGACTCCCACACTATACAGGCCCATTTGCTGAATGTGTTTGACAACATTAAATCTGTCAAGTTCCACGAAAAGATCTATGATCGA
ATTCTGTCAATTTCCTCTCAAGAGGGTGAGACGATTGAATTGGATAAACCTGTCATGGCAGAGGGCAATGTGGAAGTTTGGCTTAATTCT
CTTTTGGAAGAATCTCAGTCCTCATTGCATCTTGTGATTCGCCAGGCAGCCGCAAATATTCAAGAAACAGGTTTCCAACTAACTGAATTT
CTTTCATCCTTCCCTGCTCAGGTTGGATTATTAGGAATTCAGATGATATGGACACGGGATTCAGAAGAAGCCCTTAGAAATGCCAAGTTT
GATAAAAAAATCATGCAGAAAACTAATCAGGCTTTCCTGGAGCTACTCAATACATTGATAGACGTCACCACGAGGGATCTGAGTTCCACG
GAACGAGTGAAATACGAGACTCTGATTACTATTCATGTGCACCAAAGGGATATCTTTGATGACCTGTGTCATATGCATATCAAGAGTCCC
ATGGACTTTGAGTGGCTGAAACAGTGCAGATTTTACTTTAACGAAGATTCTGACAAGATGATGATTCACATCACAGATGTGGCGTTCATA
TACCAGAATGAATTTTTAGGCTGCACTGACAGGCTTGTAATAACTCCACTTACAGACAGATGTTACATCACGCTGGCTCAAGCTCTGGGA
ATGAGCATGGGGGGAGCCCCTGCTGGACCTGCAGGCACAGGCAAAACAGAAACCACTAAAGACATGGGACGATGCCTCGGGAAATACGTC
GTGGTTTTCAATTGTTCAGACCAGATGGATTTCCGAGGACTTGGACGGATTTTTAAGGGACTGGCACAGTCTGGATCCTGGGGTTGTTTT
GATGAATTTAACCGTATTGATCTACCAGTTCTCTCGGTTGCAGCCCAGCAAATTTCCATTATTCTGACATGTAAAAAGGAGCACAAAAAG
TCTTTTATCTTTACTGATGGAGATAATGTGACTATGAACCCTGAATTTGGGCTTTTCTTAACCATGAATCCTGGCTATGCCGGACGGCAG
GAACTCCCTGAAAACTTGAAGATTAATTTCCGCTCAGTGGCCATGATGGTGCCTGACCGTCAGATTATCATAAGGGTGAAGTTGGCTAGT
TGTGGCTTCATTGACAACGTTGTTTTGGCCAGGAAGTTTTTCACGCTCTACAAACTGTGTGAGGAGCAGCTTTCTAAGCAGGTTCATTAT
GACTTTGGCCTGCGTAACATTCTGTCAGTTCTTCGGACCTTGGGAGCAGCAAAAAGAGCCAATCCAATGGATACGGAGTCCACGATTGTC
ATGCGTGTACTACGGGACATGAATCTTTCTAAACTGATTGATGAGGATGAACCCTTGTTTTTGAGTTTGATTGAAGATCTCTTTCCAAAT
ATTCTTCTGGACAAGGCAGGTTACCCTGAACTGGAAGCAGCAATTAGTAGACAGGTTGAAGAAGCTGGTTTAATCAACCATCCTCCTTGG
AAACTGAAGGTCATCCAGCTATTCGAAACGCAGAGAGTGCGACATGGGATGATGACTCTGGGGCCCAGTGGGGCTGGGAAGACCACCTGC
ATCCACACCTTGATGAGAGCCATGACAGATTGTGGAAAACCACATCGGGAAATGAGGATGAATCCCAAAGCGATTACTGCCCCACAGATG
TTTGGTCGGCTGGACGTTGCCACAAATGACTGGACTGATGGGATATTTTCTACGCTTTGGAGGAAAACATTAAGAGCAAAGAAAGGGGAA
CATATCTGGATAATTCTTGATGGTCCAGTAGATGCCATCTGGATTGAAAATCTGAATTCTGTTTTGGATGATAACAAAACTCTAACCCTT
GCCAATGGTGATCGGATTCCCATGGCTCCAAACTGCAAGATCATTTTCGAGCCTCATAACATTGACAATGCTTCTCCTGCCACCGTCTCA
AGAAATGGAATGGTTTTCATGAGCTCTTCTATCCTTGATTGGAGTCCTATTCTTGAGGGTTTTCTTAAGAAACGCTCACCTCAAGAAGCA
GAAATTCTTCGTCAGCTGTACACCGAGTCTTTCCCAGACTTGTATCGCTTCTGTATCCAGAACTTAGAATACAAGATGGAGGTGCTGGAG
GCCTTTGTCATCACACAGAGCATTAACATGCTTCAAGGCCTGATTCCTCTGAAGGAGCAAGGCGGGGAGGTGAGCCAGGCTCACCTGGGG
CGGCTGTTCGTGTTCGCGCTGCTGTGGAGCGCGGGGGCGGCGCTGGAGCTGGACGGACGGCGCCGCCTGGAGCTCTGGCTGCGCTCTCGG
CCCACAGGGACGCTGGAGCTGCCGCCGCCAGCGGGGCCCGGGGACACCGCCTTCGACTACTATGTGGCGCCCGATGGTACATGGACGCAC
TGGAACACGCGTACCCAGGAATACCTGTATCCGTCTGATACCACCCCAGAGTATGGTTCTATTCTGGTGCCAAATGTTGACAATGTGAGG
ACTGACTTTCTAATTCAAACCATTGCTAAACAGGGCAAGGCTGTGCTATTAATTGGTGAACAAGGAACAGCCAAAACAGTAATAATTAAA
GGATTTATGTCAAAATATGATCCTGAATGTCACATGATCAAGAGTCTGAATTTTTCTTCTGCAACCACCCCACTGATGTTCCAGAGGACG
ATAGAGAGCTATGTGGATAAACGAATGGGTACAACATATGGCCCTCCTGCGGGAAAGAAGATGACTGTTTTTATTGATGATGTGAATATG
CCAATAATCAATGAGTGGGGAGATCAGGTTACGAATGAGATAGTGCGACAGCTGATGGAACAAAATGGATTCTATAATCTAGAGAAGCCT
GGGGAGTTCACCAGCATCGTGGACATCCAGTTTTTGGCAGCCATGATCCATCCTGGTGGTGGACGCAATGACATACCCCAAAGACTCAAG
AGGCAGTTCTCTATATTTAATTGCACGTTGCCCTCTGAAGCTTCTGTGGACAAGATCTTTGGTGTGATTGGGGTAGGCCACTACTGTACT
CAGAGGGGTTTCTCAGAAGAAGTGAGAGATTCTGTGACAAAATTGGTGCCTCTGACACGCCGACTATGGCAGATGACCAAGATTAAAATG
CTTCCTACCCCTGCAAAATTCCATTATGTGTTTAACCTACGAGATCTTTCTCGGGTCTGGCAGGGAATGCTGAACACTACTTCAGAGGTC
ATCAAGGAACCAAATGATCTGTTAAAGCTGTGGAAGCATGAGTGTAAACGTGTTATAGCTGACCGTTTCACAGTGTCCAGTGATGTGACC
TGGTTTGATAAGGCTTTAGTAAGTTTGGTAGAGGAGGAGTTTGGTGAAGAGAAAAAACTCTTGGTGGATTGTGGAATTGACACATATTTT
GTGGATTTCTTGAGAGATGCACCTGAAGCTGCAGGTGAAACATCTGAAGAGGCTGATGCTGAAACACCTAAAATTTATGAGCCAATTGAA
TCTTTTAGTCACCTAAAAGAGCGTCTGAATATGTTCCTGCAGCTCTATAATGAGAGCATCCGTGGCGCCGGCATGGACATGGTGTTCTTT
GCAGATGCCATGGTTCACTTAGTCAAGATCTCTCGTGTCATTCGTACTCCTCAGGGAAATGCCCTCCTGGTCGGGGTGGGCGGATCAGGA
AAGCAGAGCCTGACGAGGTTGGCTTCATTCATTGCTGGCTACGTTTCCTTCCAGATCACTCTGACGAGATCCTACAACACATCAAATCTG
ATGGAAGATCTGAAGGTTTTGTATCGAACAGCTGGTCAGCAAGGCAAAGGAATCACTTTTATTTTCACAGACAATGAGATTAAAGATGAG
TCATTTTTGGAATATATGAACAATGTTTTATCATCAGGTGAGGTCTCTAACCTATTTGCTCGAGATGAAATTGATGAAATTAATAGCGAC
CTGGCATCAGTCATGAAAAAAGAATTCCCCAGGTGCCTTCCTACCAATGAGAACCTGCACGACTACTTCATGAGTCGGGTCCGACAGAAC
CTTCATATTGTGCTCTGCTTCTCGCCAGTGGGGGAGAAATTTCGAAACAGAGCTTTGAAGTTCCCTGCCCTAATTTCAGGATGCACAATT
GACTGGTTCAGCCGATGGCCCAAAGATGCTTTAGTTGCTGTGTCTGAACACTTCCTCACTTCCTATGATATTGACTGCAGTTTGGAAATC
AAGAAGGAGGTGGTCCAATGCATGGGCTCCTTCCAGGATGGGGTGGCTGAGAAGTGTGTTGATTATTTTCAGAGATTCCGACGTTCTACC
CACGTGACGCCCAAATCATACCTCTCCTTTATTCAGGGCTATAAGTTCATATATGGAGAAAAGCATGTGGAGGTGCGGACCCTGGCCAAC
AGAATGAATACTGGATTGGAAAAGCTCAAAGAAGCTTCAGAGTCTGTTGCAGCCTTGAGTAAAGAACTGGAAGCGAAAGAAAAGGAGCTA
CAAGTGGCCAACGATAAAGCCGACATGGTCTTAAAAGAAGTGACAATGAAAGCACAGGCTGCTGAAAAGGTCAAGGCTGAGGTACAGAAG
GTGAAGGACAGGGCCCAGGCCATTGTGGACAGCATCTCTAAAGACAAAGCCATTGCTGAAGAAAAACTGGAAGCAGCAAAACCAGCTTTA
GAAGAGGCAGAAGCTGCATTGCAGACCATCAGGCCTTCGGACATCGCCACTGTTCGCACGTTGGGCCGCCCCCCTCACCTCATCATGCGG
ATCATGGATTGCGTACTGCTGCTGTTTCAAAGGAAAGTCAGTGCTGTGAAAATTGACCTGGAAAAAAGCTGTACCATGCCCTCCTGGCAG
GAATCCTTAAAATTGATGACTGCAGGGAACTTTTTACAGAACTTACAGCAATTCCCAAAAGACACAATCAATGAAGAGGTGATAGAATTT
TTGAGTCCTTACTTTGAAATGCCTGACTATAACATCGAAACTGCTAAACGCGTATGTGGAAATGTAGCTGGTCTTTGTTCCTGGACGAAA
GCTATGGCTTCCTTCTTTTCTATAAACAAAGAAGTACTGCCTCTGAAGGCCAACTTGGTGGTGCAAGAGAATCGCCATCTCCTGGCCATG
CAGGATCTGCAGAAAGCCCAGGCCGAGTTGGATGACAAGCAGGCGGAACTTGACGTGGTGCAGGCTGAGTATGAACAGGCCATGACTGAA
AAGCAGACCTTGCTTGAAGATGCAGAGCGATGCAGACACAAGATGCAGACAGCTTCCACGCTCATCAGTGGCTTGGCAGGTGAAAAAGAA
AGATGGACAGAGCAAAGCCAAGAGTTTGCTGCACAAACTAAAAGACTTGTAGGGGATGTACTGTTGGCTACAGCTTTTCTATCTTATTCT
GGTCCATTTAACCAAGAGTTTCGTGATCTTCTGTTAAATGACTGGCGGAAGGAAATGAAAGCCCGGAAAATTCCATTTGGAAAGAACCTA
AATCTCAGTGAGATGTTGATTGATGCTCCTACTATTAGTGAATGGAACCTCCAAGGTCTGCCAAATGATGACTTGTCCATTCAAAATGGA
ATTATTGTCACGAAGGCATCTCGTTACCCTTTGTTAATTGATCCACAGACTCAAGGCAAGATCTGGATTAAAAATAAAGAAAGCCGAAAT
GAACTCCAGATCACGTCTTTAAATCACAAGTACTTCAGAAACCACCTGGAAGACAGCCTTTCTCTTGGAAGGCCTTTGCTTATTGAAGAT
GTTGGAGAGGAACTAGATCCAGCACTAGATAATGTTTTGGAAAGAAACTTCATTAAAACTGGGTCTACCTTTAAGGTGAAAGTTGGTGAC
AAGGAAGTAGATGTGTTGGATGGCTTTAGACTCTACATTACCACCAAATTGCCTAACCCAGCCTACACCCCTGAGATAAGTGCCCGTACC
TCCATCATTGACTTCACTGTCACCATGAAAGGTCTAGAAGATCAGTTACTGGGGAGGGTCATTCTCACAGAGAAGCAGGAATTGGAGAAA
GAAAGAACTCATCTGATGGAAGATGTAACTGCAAACAAAAGAAGGATGAAGGAACTAGAAGATAACTTGCTTTACCGCCTGACAAGTACC
CAGGGGTCCCTGGTAGAAGATGAAAGTCTCATTGTCGTGCTGAGTAACACAAAAAGGACAGCCGAGGAGGTGACACAGAAGCTAGAAATT
TCTGCTGAGACAGAAGTTCAAATTAACTCAGCCCGGGAGGAATACAGACCTGTGGCTACGCGGGGCAGCATCCTCTACTTCCTCATTACT
GAGATGCGCTTGGTTAATGAGATGTATCAGACTTCGCTTCGCCAGTTTCTGGGCTTATTTGACCTTTCCTTAGCCAGGTCTGTCAAGAGC
CCGATTACAAGCAAGAGGATTGCTAATATCATCGAGCACATGACCTACGAGGTTTATAAGTATGCTGCCCGAGGGCTGTACGAGGAGCAC
AAATTCCTGTTCACCTTGTTGCTTACCCTAAAGATTGACATCCAGAGGAACCGAGTCAAGCATGAAGAGTTTCTCACTCTTATTAAAGGA
GGTGCCTCATTAGACCTTAAAGCTTGTCCTCCAAAACCATCAAAATGGATCCTGGACATAACATGGCTGAATTTGGTGGAACTTAGCAAA
CTCAGACAGTTTTCAGATGTCCTTGACCAGATATCGAGAAATGAGAAAATGTGGAAAATTTGGTTTGATAAGGAAAACCCGGAGGAGGAA
CCTCTTCCAAATGCCTATGATAAATCTCTTGACTGCTTCAGACGTCTTCTCCTTATTAGATCCTGGTGTCCTGACAGAACCATCGCCCAG
GCCCGCAAGTACATCGTGGACTCCATGGGAGAAAAATATGCCGAAGGTGTTATTTTAGACTTGGAGAAGACGTGGGAGGAATCTGATCCA
CGGACGCCACTCATCTGTCTCCTGTCTATGGGCTCAGACCCCACAGATTCCATCATTGCCTTGGGGAAGAGATTAAAAATAGAAACCCGT
TATGTGTCCATGGGCCAGGGCCAGGAAGTCCATGCTCGGAAGCTCTTGCAGCAGACCATGGCGAACGGAGGATGGGCACTTCTGCAGAAC
TGCCATCTGGGACTTGATTTCATGGATGAGCTGATGGACATAATCATAGAAACTGAGCTTGTACATGATGCGTTCCGCCTCTGGATGACC
ACCGAGGCTCATAAGCAGTTTCCCATTACACTCCTTCAGATGTCCATTAAATTTGCCAACGATCCTCCACAAGGACTCCGGGCAGGACTG
AAAAGAACATATAGTGGTGTCAGCCAAGACCTGCTGGACGTGAGCTCTGGGTCCCAGTGGAAGCCCATGCTGTACGCAGTGGCTTTCCTG
CACTCCACTGTCCAGGAGAGGCGCAAGTTCGGTGCCCTGGGGTGGAATATCCCCTACGAATTTAACCAAGCGGACTTTAATGCCACTGTG
CAGTTCATCCAAAACCACTTGGATGACATGGATGTCAAAAAGGGTGTCTCCTGGACCACCATCCGCTACATGATAGGAGAGATTCAATAT
GGAGGCAGAGTCACTGACGACTATGATAAGAGATTGTTGAACACATTTGCTAAGGTTTGGTTCAGTGAAAATATGTTTGGACCAGATTTC
AGTTTTTACCAAGGATACAATATTCCAAAATGCAGCACAGTGGATAACTATCTTCAGTATATCCAGAGTTTGCCTGCCTATGACAGCCCT
GAGGTGTTTGGGCTGCACCCCAATGCTGACATCACCTACCAGAGCAAGCTGGCCAAGGACGTGCTGGACACCATCCTAGGCATCCAACCC
AAGGACACCTCTGGTGGAGGGGATGAGACCCGGGAGGCGGTGGTGGCCCGGCTGGCTGATGATATGCTGGAGAAGCTGCCCCCAGACTAT
GTCCCCTTTGAAGTAAAAGAGAGGCTGCAGAAGATGGGGCCATTCCAGCCTATGAACATTTTCCTCAGGCAGGAAATAGACAGAATGCAA
AGGGTACTCAGCCTTGTCCGCAGCACCCTCACTGAGCTGAAACTTGCTATTGATGGCACCATCATCATGAGCGAAAATCTGCGAGATGCA
TTGGATTGCATGTTTGATGCTAGAATCCCTGCTTGGTGGAAAAAAGCTTCTTGGATTTCTAGTACACTGGGTTTCTGGTTTACTGAACTT
ATAGAAAGAAACAGCCAGTTTACCTCGTGGGTTTTCAATGGCCGACCTCACTGCTTTTGGATGACGGGTTTTTTTAACCCCCAGGGATTT
TTAACTGCAATGCGACAGGAAATAACTCGGGCCAACAAAGGCTGGGCTCTGGACAATATGGTGCTTTGCAATGAAGTCACCAAATGGATG
AAGGACGACATTTCTGCCCCTCCCACAGAGGGTGTCTATGTCTATGGCTTATATCTTGAAGGTGCTGGCTGGGACAAGAGGAACATGAAA
CTCATTGAATCAAAGCCAAAAGTGCTCTTTGAGTTGATGCCTGTCATAAGGATTTATGCAGAAAACAATACTTTACGAGATCCTCGGTTT
TACTCCTGTCCCATCTATAAGAAGCCAGTTCGAACGGACTTGAACTACATTGCCGCTGTGGATCTCAGGACAGCCCAGACCCCTGAACAC
TGGGTGCTCCGTGGGGTTGCCCTTCTGTGTGATGTCAAGTAACATGTGGGGAGTGTCCCCACCCAATGCTTTGGAAAATGCAAGATCTAA
ATTATTGTAACCTTTATTTCTGTATGACTGCTGGACAGTGTATGTTAGGTCGTTTATGCAATTAATGAGCTGCATAGGTTTTCCCCACTC
CTTAATTGGATGCTTATATTTTACTTGTTTCATCATTAGTGACCAATGTCTGAGTTTGTTGAAAATGTTATTTAGTGATATAAAAGTAAA
TTTACAGCATCCTAATGAAGTGTGGCCCTCAAATCCACAGTAGTATATTTTCTTCTTACTTCGCTCCGAAGACTGACTAGGGTAAGCAGA
CAGTATTTCTCTGGGAGGAATTATTCTTCTGTTAACGTGGCCTGGTAACAGCCAAGTTCTTGAAGGTAACAGGGCAAGTCTGTGCTGATT
TTGCTTCTATTGCCTTTCGTATTTAGGTCAAGTTAAGAGACTTATTTTCAGGGTTTCAAGCAGCCAATTAAAAATACCTTTTAAAAAATA
GAAGGAAATAGAAGAATGGATTAAGAATGTAAATAGAAAATTTATGTAAACATAGAGAATAAACGTAGAACAATGCTTAAGCCTACTTAT
AATTAATAATGAAATACTAATTGATAATTCTTATAATAAAAATTAAAGCTAAAAGTAAATGATAGCATGCTCTCAGTAAAACTGATCCAC
TCACAAATTGCTGGAGCAATGTAAATCAACCCAACCTTTTTGTAAAATGATTAAATACAGAAAGAGCCATAAAAATATTCACACCCTTGG
ATCTTTGTTTTCTCTACATCAAGGAAACAATTTAAAAGACTGAAAACAGTCTATATAAAATTGCATTTAATAACAGAAAAAAATGGAAAA
ATCATAAATATTCAATAGTCAGGCTATGGTTAAGGAAATTAAGAGATATTTGGCAACCATAAAAAACAATTTTGAAGATTCCATAATATG
AAATGGTAGACCCAGACTGTTAAGTGAAAGATTTAGTTTACAAAATATTGAGCACACTGTGATTATAACAGCAAATATATTTGCATGTGG
ACAAAGATTAGATGGCAAGATAGAAAAATAAGAACAGATGTGATAGCAAGAATTATAGTTGGCTTGAAAAAATGTGATGATCAGGAGAAA
AAATAAAAAAAGGGTAGAAATATTAGACGGTGCGTAGGGACTTTCTATGGACTTTTATTAATTAGGAAACATTATCAAAGGAACTTTTCA
CGTATTTTTCTTTAAATTCTGGTTAGATGTTATTAATAATTCTTCATCTAACCTACTGACTAGAAAATATAGTCAGTACTAAATTAGAAT
TGTGGTTTATAAACTTTTGGTTAGCTCTGGATCTGTATAACTGCATTTTTTTGGATAAACAGTTTTTGGTAGGTGGATACCGGGAGACAA
GTGTGGGTCCCTCTCACTGGGCTTCATTCTGTGGACCAGGATCATTATTTCATGCTCATGATCATGAGAGTTAGGACTGAGTGGCTCCTG
TGACTCCCACCATCTTAGATGATACTGTTTTCTTGTGAGTTCTTTCTTTTGGTGTGGATTAGTATATCAGTTGATTTGTGTGAATTGTGG

>94199_94199_3_TRIO-DNAH5_TRIO_chr5_14391099_ENST00000537187_DNAH5_chr5_13931353_ENST00000265104_length(amino acids)=6011AA_BP=1404
MSGSSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEMKAMDVLPILKEKVAYLSGGRDKRGGPILTF
PARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFE
TNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDILAKKELPQDLEGARNMIEEHSQLKKKVIKA
PIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNK
GLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIRQIASQLEQEWKAFAAALDERSTLLDMSSIF
HQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYSEVSQDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDV
IHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYTNADKLLEA
AEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTT
LQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKIKLELFLQLRIFERDAIDIISDLESWNDELS
QQMNDFDTEDLTIAEQRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHR
KHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKTHQSALQVQQKAEAMLQANHYDMDMIRDCAE
KVASHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRN
ADVFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQYVVFERSAKQALEWIHDNGEFYLSTHTSTGS
SIQHTQELLKEHEEFQITAKQTKERVKLLIQLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQ
LDIIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFGNMQEIYEF
HNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAGSYFDQRLKGEKEAKRALLDARHNYLFAIVASCLDLNKT
EVEDAILEGNQIERIDQLFAVGGLRHLMFYYQDVEEAETGQLGSLGGVNLVSGKIKKPKVFVTEGNDVALTGVCVFFIRTDPSKAITPDN
IHQEVSFNMLDAADGGLLNSVRRLLSDIFIPALRATSHGWGELEGLQDAANIRQEFLSSLEGFVNVLSGAQESLKEKVNLRKCDILELKT
LKEPTDYLTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLKEADDVGPRAELEHWKKRLSKFNYLLEQLKSPDVKAVLAVLAAAKSKL
LKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYSSDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYIT
NNGTASIWNQPQDVVEEKILSAIKLKQEYQLCFHKTKQKLKQNPNAKQFDFSEMYIFGKFETFHRRLAKIIDIFTTLKTYSVLQDSTIEG
LEDMATKYQGIVATIKKKEYNFLDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNTNQALRMLKKFERLNIPNLGIDDKYQLIL
ENYGADIDMISKLYTKQKYDPPLARNQPPIAGKILWARQLFHRIQQPMQLFQQHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLR
QIEEIHVGLEASLLVKAPGTGELFVNFDPQILILFRETECMAQMGLEVSPLATSLFQKRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQL
IVPHLAKVDEALQPGLAALTWTSLNIEAYLENTFAKIKDLELLLDRVNDLIEFRIDAILEEMSSTPLCQLPQEEPLTCEEFLQMTKDLCV
NGAQILHFKSSLVEEAVNELVNMLLDVEVLSEEESEKISNENSVNYKNESSAKREEGNFDTLTSSINARANALLLTTVTRKKKETEMLGE
EARELLSHFNHQNMDALLKVTRNTLEAIRKRIHSSHTINFRDSNSASNMKQNSLPIFRASVTLAIPNIVMAPALEDVQQTLNKAVECIIS
VPKGVRQWSSELLSKKKIQERKMAALQSNEDSDSDVEMGENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKE
VITSMDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILYFQNLEQEINAEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNK
KYRSEMENIFMLIEEFNKKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKVDTLHYAWEKLLARA
GEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMASGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLL
EIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSECCPLLEYMASKAMME
RHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIA
NMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVP
SVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRIL
SISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDK
KIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQ
NEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDE
FNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCG
FIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNIL
LDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFG
RLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRN
GMVFMSSSILDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKMEVLEAFVITQSINMLQGLIPLKEQGGEVSQAHLGRL
FVFALLWSAGAALELDGRRRLELWLRSRPTGTLELPPPAGPGDTAFDYYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTD
FLIQTIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPI
INEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQR
GFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVTWF
DKALVSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFAD
AMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESF
LEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDW
FSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRM
NTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEE
AEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLS
PYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQ
TLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRKEMKARKIPFGKNLNL
SEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVG
EELDPALDNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKER
THLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEM
RLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGA
SLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQAR
KYIVDSMGEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETRYVSMGQGQEVHARKLLQQTMANGGWALLQNCH
LGLDFMDELMDIIIETELVHDAFRLWMTTEAHKQFPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPMLYAVAFLHS
TVQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGPDFSF
YQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVP
FEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWISSTLGFWFTELIE
RNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TRIO-DNAH5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TRIO-DNAH5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TRIO-DNAH5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource