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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TRIP12-DNER (FusionGDB2 ID:94239)

Fusion Gene Summary for TRIP12-DNER

check button Fusion gene summary
Fusion gene informationFusion gene name: TRIP12-DNER
Fusion gene ID: 94239
HgeneTgene
Gene symbol

TRIP12

DNER

Gene ID

9320

92737

Gene namethyroid hormone receptor interactor 12delta/notch like EGF repeat containing
SynonymsMRD49|TRIP-12|TRIPC|ULFUNQ26|bet
Cytomap

2q36.3

2q36.3

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase TRIP12E3 ubiquitin-protein ligase for ArfHECT-type E3 ubiquitin transferase TRIP12TR-interacting protein 12probable E3 ubiquitin-protein ligase TRIP12thyroid receptor interacting protein 12delta and Notch-like epidermal growth factor-related receptorH_NH0150O02.1WUGSC:H_NH0150O02.1delta-notch-like EGF repeat-containing transmembrane
Modification date2020031320200313
UniProtAcc.

Q8NFT8

Ensembl transtripts involved in fusion geneENST00000283943, ENST00000389044, 
ENST00000389045, ENST00000409677, 
ENST00000543084, 		ENST00000482831, 
ENST00000341772, 
Fusion gene scores* DoF score20 X 18 X 15=54005 X 3 X 4=60
# samples 297
** MAII scorelog2(29/5400*10)=-4.21883460192326
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/60*10)=0.222392421336448
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: TRIP12 [Title/Abstract] AND DNER [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDNER(230411663)-TRIP12(230650571), # samples:2
TRIP12(230642030)-DNER(230456604), # samples:1
TRIP12(230786596)-DNER(230456604), # samples:1
TRIP12(230786280)-DNER(230456604), # samples:1
TRIP12(230642031)-DNER(230456604), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTRIP12

GO:0000209

protein polyubiquitination

30982744

HgeneTRIP12

GO:0006511

ubiquitin-dependent protein catabolic process

18627766|20208519|30982744


check buttonFusion gene breakpoints across TRIP12 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DNER (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-CR-6467TRIP12chr2

230786280

-DNERchr2

230456604

-
ChimerDB4HNSCTCGA-CR-6467TRIP12chr2

230786596

-DNERchr2

230456604

-
ChimerDB4LUADTCGA-50-5930-01ATRIP12chr2

230642031

-DNERchr2

230456604

-
ChimerDB4LUADTCGA-50-5930TRIP12chr2

230642030

-DNERchr2

230456604

-


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Fusion Gene ORF analysis for TRIP12-DNER

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000283943ENST00000482831TRIP12chr2

230642031

-DNERchr2

230456604

-
5CDS-intronENST00000283943ENST00000482831TRIP12chr2

230642030

-DNERchr2

230456604

-
5CDS-intronENST00000389044ENST00000482831TRIP12chr2

230642031

-DNERchr2

230456604

-
5CDS-intronENST00000389044ENST00000482831TRIP12chr2

230642030

-DNERchr2

230456604

-
5CDS-intronENST00000389045ENST00000482831TRIP12chr2

230642031

-DNERchr2

230456604

-
5CDS-intronENST00000389045ENST00000482831TRIP12chr2

230642030

-DNERchr2

230456604

-
5UTR-3CDSENST00000283943ENST00000341772TRIP12chr2

230786596

-DNERchr2

230456604

-
5UTR-3CDSENST00000389044ENST00000341772TRIP12chr2

230786596

-DNERchr2

230456604

-
5UTR-3CDSENST00000389045ENST00000341772TRIP12chr2

230786596

-DNERchr2

230456604

-
5UTR-3CDSENST00000409677ENST00000341772TRIP12chr2

230786596

-DNERchr2

230456604

-
5UTR-3CDSENST00000543084ENST00000341772TRIP12chr2

230786596

-DNERchr2

230456604

-
5UTR-intronENST00000283943ENST00000482831TRIP12chr2

230786596

-DNERchr2

230456604

-
5UTR-intronENST00000389044ENST00000482831TRIP12chr2

230786596

-DNERchr2

230456604

-
5UTR-intronENST00000389045ENST00000482831TRIP12chr2

230786596

-DNERchr2

230456604

-
5UTR-intronENST00000409677ENST00000482831TRIP12chr2

230786596

-DNERchr2

230456604

-
5UTR-intronENST00000543084ENST00000482831TRIP12chr2

230786596

-DNERchr2

230456604

-
In-frameENST00000283943ENST00000341772TRIP12chr2

230642031

-DNERchr2

230456604

-
In-frameENST00000283943ENST00000341772TRIP12chr2

230642030

-DNERchr2

230456604

-
In-frameENST00000389044ENST00000341772TRIP12chr2

230642031

-DNERchr2

230456604

-
In-frameENST00000389044ENST00000341772TRIP12chr2

230642030

-DNERchr2

230456604

-
In-frameENST00000389045ENST00000341772TRIP12chr2

230642031

-DNERchr2

230456604

-
In-frameENST00000389045ENST00000341772TRIP12chr2

230642030

-DNERchr2

230456604

-
intron-3CDSENST00000283943ENST00000341772TRIP12chr2

230786280

-DNERchr2

230456604

-
intron-3CDSENST00000389044ENST00000341772TRIP12chr2

230786280

-DNERchr2

230456604

-
intron-3CDSENST00000389045ENST00000341772TRIP12chr2

230786280

-DNERchr2

230456604

-
intron-3CDSENST00000409677ENST00000341772TRIP12chr2

230786280

-DNERchr2

230456604

-
intron-3CDSENST00000409677ENST00000341772TRIP12chr2

230642031

-DNERchr2

230456604

-
intron-3CDSENST00000409677ENST00000341772TRIP12chr2

230642030

-DNERchr2

230456604

-
intron-3CDSENST00000543084ENST00000341772TRIP12chr2

230786280

-DNERchr2

230456604

-
intron-3CDSENST00000543084ENST00000341772TRIP12chr2

230642031

-DNERchr2

230456604

-
intron-3CDSENST00000543084ENST00000341772TRIP12chr2

230642030

-DNERchr2

230456604

-
intron-intronENST00000283943ENST00000482831TRIP12chr2

230786280

-DNERchr2

230456604

-
intron-intronENST00000389044ENST00000482831TRIP12chr2

230786280

-DNERchr2

230456604

-
intron-intronENST00000389045ENST00000482831TRIP12chr2

230786280

-DNERchr2

230456604

-
intron-intronENST00000409677ENST00000482831TRIP12chr2

230786280

-DNERchr2

230456604

-
intron-intronENST00000409677ENST00000482831TRIP12chr2

230642031

-DNERchr2

230456604

-
intron-intronENST00000409677ENST00000482831TRIP12chr2

230642030

-DNERchr2

230456604

-
intron-intronENST00000543084ENST00000482831TRIP12chr2

230786280

-DNERchr2

230456604

-
intron-intronENST00000543084ENST00000482831TRIP12chr2

230642031

-DNERchr2

230456604

-
intron-intronENST00000543084ENST00000482831TRIP12chr2

230642030

-DNERchr2

230456604

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000283943TRIP12chr2230642030-ENST00000341772DNERchr2230456604-8332548317974202413
ENST00000389045TRIP12chr2230642030-ENST00000341772DNERchr2230456604-741645677365042143
ENST00000389044TRIP12chr2230642030-ENST00000341772DNERchr2230456604-8466561716975542461
ENST00000283943TRIP12chr2230642031-ENST00000341772DNERchr2230456604-8332548317974202413
ENST00000389045TRIP12chr2230642031-ENST00000341772DNERchr2230456604-741645677365042143
ENST00000389044TRIP12chr2230642031-ENST00000341772DNERchr2230456604-8466561716975542461

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000283943ENST00000341772TRIP12chr2230642030-DNERchr2230456604-0.0007259140.9992741
ENST00000389045ENST00000341772TRIP12chr2230642030-DNERchr2230456604-0.0005160590.99948394
ENST00000389044ENST00000341772TRIP12chr2230642030-DNERchr2230456604-0.0006827020.9993173
ENST00000283943ENST00000341772TRIP12chr2230642031-DNERchr2230456604-0.0007259140.9992741
ENST00000389045ENST00000341772TRIP12chr2230642031-DNERchr2230456604-0.0005160590.99948394
ENST00000389044ENST00000341772TRIP12chr2230642031-DNERchr2230456604-0.0006827020.9993173

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Fusion Genomic Features for TRIP12-DNER


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TRIP12-DNER


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:230411663/chr2:230650571)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.DNER

Q8NFT8

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRIP12chr2:230642030chr2:230456604ENST00000283943-3641749_83617681993.0DomainWWE
HgeneTRIP12chr2:230642030chr2:230456604ENST00000389044-3742749_83618162041.0DomainWWE
HgeneTRIP12chr2:230642030chr2:230456604ENST00000389045-3439749_83614981723.0DomainWWE
HgeneTRIP12chr2:230642031chr2:230456604ENST00000283943-3641749_83617681993.0DomainWWE
HgeneTRIP12chr2:230642031chr2:230456604ENST00000389044-3742749_83618162041.0DomainWWE
HgeneTRIP12chr2:230642031chr2:230456604ENST00000389045-3439749_83614981723.0DomainWWE
HgeneTRIP12chr2:230642030chr2:230456604ENST00000283943-36411496_157017681993.0RegionNote=K-box
HgeneTRIP12chr2:230642030chr2:230456604ENST00000389044-37421496_157018162041.0RegionNote=K-box
HgeneTRIP12chr2:230642031chr2:230456604ENST00000283943-36411496_157017681993.0RegionNote=K-box
HgeneTRIP12chr2:230642031chr2:230456604ENST00000389044-37421496_157018162041.0RegionNote=K-box
TgeneDNERchr2:230642030chr2:230456604ENST00000341772013309_34892738.0DomainEGF-like 3
TgeneDNERchr2:230642030chr2:230456604ENST00000341772013349_39092738.0DomainEGF-like 4
TgeneDNERchr2:230642030chr2:230456604ENST00000341772013392_42892738.0DomainEGF-like 5
TgeneDNERchr2:230642030chr2:230456604ENST00000341772013430_46692738.0DomainEGF-like 6
TgeneDNERchr2:230642030chr2:230456604ENST00000341772013468_50392738.0DomainEGF-like 7
TgeneDNERchr2:230642030chr2:230456604ENST00000341772013505_54192738.0DomainEGF-like 8%3B calcium-binding
TgeneDNERchr2:230642030chr2:230456604ENST00000341772013543_57992738.0DomainEGF-like 9
TgeneDNERchr2:230642030chr2:230456604ENST00000341772013546_56892738.0DomainNote=Follistatin-like
TgeneDNERchr2:230642030chr2:230456604ENST00000341772013581_61792738.0DomainEGF-like 10%3B calcium-binding
TgeneDNERchr2:230642030chr2:230456604ENST0000034177201394_13392738.0DomainEGF-like 2
TgeneDNERchr2:230642031chr2:230456604ENST00000341772013309_34892738.0DomainEGF-like 3
TgeneDNERchr2:230642031chr2:230456604ENST00000341772013349_39092738.0DomainEGF-like 4
TgeneDNERchr2:230642031chr2:230456604ENST00000341772013392_42892738.0DomainEGF-like 5
TgeneDNERchr2:230642031chr2:230456604ENST00000341772013430_46692738.0DomainEGF-like 6
TgeneDNERchr2:230642031chr2:230456604ENST00000341772013468_50392738.0DomainEGF-like 7
TgeneDNERchr2:230642031chr2:230456604ENST00000341772013505_54192738.0DomainEGF-like 8%3B calcium-binding
TgeneDNERchr2:230642031chr2:230456604ENST00000341772013543_57992738.0DomainEGF-like 9
TgeneDNERchr2:230642031chr2:230456604ENST00000341772013546_56892738.0DomainNote=Follistatin-like
TgeneDNERchr2:230642031chr2:230456604ENST00000341772013581_61792738.0DomainEGF-like 10%3B calcium-binding
TgeneDNERchr2:230642031chr2:230456604ENST0000034177201394_13392738.0DomainEGF-like 2
TgeneDNERchr2:230642030chr2:230456604ENST00000341772013662_73792738.0Topological domainCytoplasmic
TgeneDNERchr2:230642031chr2:230456604ENST00000341772013662_73792738.0Topological domainCytoplasmic
TgeneDNERchr2:230642030chr2:230456604ENST00000341772013641_66192738.0TransmembraneHelical
TgeneDNERchr2:230642031chr2:230456604ENST00000341772013641_66192738.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRIP12chr2:230642030chr2:230456604ENST00000283943-36411885_199217681993.0DomainHECT
HgeneTRIP12chr2:230642030chr2:230456604ENST00000389044-37421885_199218162041.0DomainHECT
HgeneTRIP12chr2:230642030chr2:230456604ENST00000389045-34391885_199214981723.0DomainHECT
HgeneTRIP12chr2:230642031chr2:230456604ENST00000283943-36411885_199217681993.0DomainHECT
HgeneTRIP12chr2:230642031chr2:230456604ENST00000389044-37421885_199218162041.0DomainHECT
HgeneTRIP12chr2:230642031chr2:230456604ENST00000389045-34391885_199214981723.0DomainHECT
HgeneTRIP12chr2:230642030chr2:230456604ENST00000389045-34391496_157014981723.0RegionNote=K-box
HgeneTRIP12chr2:230642031chr2:230456604ENST00000389045-34391496_157014981723.0RegionNote=K-box
TgeneDNERchr2:230642030chr2:230456604ENST0000034177201344_9292738.0DomainEGF-like 1
TgeneDNERchr2:230642031chr2:230456604ENST0000034177201344_9292738.0DomainEGF-like 1
TgeneDNERchr2:230642030chr2:230456604ENST0000034177201335_64092738.0Topological domainExtracellular
TgeneDNERchr2:230642031chr2:230456604ENST0000034177201335_64092738.0Topological domainExtracellular


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Fusion Gene Sequence for TRIP12-DNER


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>94239_94239_1_TRIP12-DNER_TRIP12_chr2_230642030_ENST00000283943_DNER_chr2_230456604_ENST00000341772_length(transcript)=8332nt_BP=5483nt
GCTGCGGCTCAGCTGATAATTGAAGGAACCCGGAGCCGCCGCCGCCGCGCCGCTGGGGGGGGTGGGGGGAGCTAGTGGAAGTTACTGCCG
CGCCACCGAGTCCGGACCGGAGACTTTGGGGCCTAACTAGTGAATGGTAGTGTCTAGAAAGGGTATGTCCCTTCAAGAGAGAGGTGCCAA
TGTCCAACCGGCCTAATAACAATCCAGGGGGGTCACTGCGACGTTCACAGAGGAACACTGCCGGGGCCCAACCACAAGACGACTCAATAG
GAGGAAGAAGCTGCAGTTCATCATCTGCTGTGATAGTTCCACAACCAGAGGATCCAGACAGAGCCAATACTTCAGAAAGACAAAAAACGG
GGCAGGTGCCTAAGAAAGACAATTCTCGAGGAGTGAAGCGCAGTGCTAGTCCAGACTACAACAGGACCAATTCTCCTAGCTCTGCAAAAA
AACCAAAAGCACTTCAGCATACTGAATCTCCCTCAGAAACAAATAAGCCACATAGTAAGTCAAAGAAGAGACATTTAGACCAGGAGCAAC
AACTGAAATCTGCACAATCACCATCAACAAGCAAGGCTCATACCAGGAAGAGTGGGGCCACTGGCGGTTCACGGAGTCAGAAAAGAAAAA
GGACAGAGAGTTCTTGTGTAAAGAGTGGCTCCGGGTCTGAATCAACTGGTGCAGAAGAGAGATCTGCGAAACCTACCAAGCTGGCTTCAA
AATCAGCCACCTCAGCCAAAGCTGGGTGTAGCACCATCACTGATTCTTCTTCTGCTGCCTCTACTTCCTCCTCGTCTTCTGCTGTAGCCT
CGGCCTCCTCCACTGTACCACCAGGTGCCAGAGTGAAACAAGGAAAAGATCAGAACAAGGCCAGGCGTTCCCGTTCAGCGTCCAGTCCCA
GCCCCAGAAGAAGTAGCAGGGAAAAGGAACAGAGTAAAACTGGTGGCTCTTCAAAATTTGATTGGGCTGCTCGTTTCAGCCCTAAAGTTA
GCCTTCCTAAAACAAAACTGTCTCTTCCAGGGTCTTCTAAGTCAGAGACATCAAAACCTGGACCTTCTGGATTACAGGCCAAATTAGCAA
GTTTAAGAAAATCTACGAAGAAACGCAGTGAGTCTCCACCTGCTGAGCTCCCCAGTTTGAGGCGGAGCACACGCCAAAAGACCACGGGCT
CCTGTGCTAGTACCAGTCGGCGAGGCTCTGGCCTGGGCAAAAGAGGAGCAGCTGAAGCTCGTCGACAGGAGAAAATGGCAGACCCTGAAA
GCAACCAGGAGGCAGTAAATTCTTCAGCTGCTCGGACAGATGAAGCTCCCCAAGGAGCTGCAGGGGCTGTTGGCATGACCACCTCTGGGG
AGAGTGAATCAGATGATTCCGAGATGGGACGTTTGCAAGCTTTGTTAGAGGCAAGGGGTCTTCCCCCTCACCTATTTGGTCCTCTTGGTC
CTCGGATGTCACAGCTTTTCCATAGAACAATTGGAAGTGGAGCTAGTTCTAAGGCCCAGCAGCTACTACAAGGATTGCAAGCCAGTGATG
AAAGTCAACAGCTTCAGGCAGTTATTGAGATGTGTCAGTTACTGGTCATGGGAAATGAGGAGACACTGGGAGGGTTTCCTGTCAAGAGTG
TTGTTCCAGCTTTGATTACGTTACTTCAGATGGAGCACAATTTTGATATTATGAACCATGCTTGTCGAGCCTTAACATACATGATGGAAG
CACTTCCTCGATCTTCTGCTGTTGTAGTAGATGCTATTCCTGTCTTTTTAGAAAAGCTGCAAGTTATTCAGTGTATTGATGTGGCAGAGC
AGGCCTTGACTGCCTTGGAGATGTTGTCACGGAGACATAGTAAAGCCATTCTACAGGCGGGTGGTTTGGCAGACTGCTTGCTGTACCTAG
AATTCTTCAGCATAAATGCCCAAAGAAATGCATTAGCAATTGCAGCTAATTGCTGCCAGAGTATCACGCCAGATGAATTTCATTTTGTGG
CAGATTCACTCCCATTGCTAACCCAAAGGCTAACACATCAGGATAAAAAGTCAGTAGAAAGCACTTGCCTTTGTTTTGCACGCCTAGTGG
ACAACTTCCAGCATGAGGAGAATTTACTCCAGCAGGTTGCTTCCAAAGATCTGCTTACAAATGTTCAACAGCTGTTGGTAGTGACTCCAC
CCATTTTAAGTTCTGGGATGTTTATAATGGTGGTTCGCATGTTTTCTCTGATGTGTTCCAACTGTCCAACTTTAGCTGTTCAACTTATGA
AACAAAACATTGCAGAAACGCTTCACTTTCTCCTGTGTGGTGCCTCCAATGGAAGTTGTCAGGAACAGATTGATCTTGTTCCACGAAGCC
CTCAAGAGTTGTATGAACTGACATCTCTGATTTGTGAACTTATGCCATGTTTACCAAAAGAAGGCATTTTTGCAGTTGATACCATGTTGA
AGAAGGGAAATGCACAGAACACAGATGGTGCGATATGGCAGTGGCGTGATGATCGGGGCCTCTGGCATCCATATAACAGGATTGACAGCC
GGATCATTGAGCAAATCAATGAGGACACGGGAACAGCACGTGCCATTCAGAGAAAACCTAACCCGTTAGCCAATAGTAACACTAGTGGAT
ATTCAGAGTCAAAGAAGGATGATGCTCGAGCACAGCTTATGAAAGAGGATCCGGAACTGGCTAAGTCTTTTATTAAGACATTATTTGGTG
TTCTTTATGAAGTGTATAGTTCCTCAGCAGGACCTGCGGTCAGACATAAGTGCCTTAGAGCAATTCTTAGGATAATTTATTTTGCGGATG
CTGAACTTCTGAAGGATGTTCTGAAAAATCATGCTGTTTCAAGTCACATTGCTTCCATGCTGTCAAGCCAAGACCTGAAGATAGTAGTGG
GAGCACTTCAGATGGCAGAAATTTTAATGCAGAAGTTACCTGATATTTTTAGTGTTTACTTCAGAAGAGAAGGTGTAATGCATCAAGTAA
AACACTTAGCAGAATCAGAGTCTTTGTTGACAAGTCCACCAAAGGCATGTACGAATGGATCGGGATCCATGGGATCCACAACTTCAGTCA
GCAGTGGGACAGCCACAGCTGCCACTCATGCTGCAGCTGACTTGGGATCACCCAGCTTGCAGCACAGCAGGGATGATTCTTTAGATCTCA
GCCCTCAAGGTCGATTAAGTGATGTTCTAAAGAGAAAACGACTGCCAAAACGAGGGCCAAGAAGGCCAAAGTACTCACCTCCAAGAGATG
ATGACAAAGTAGACAATCAAGCTAAAAGCCCCACCACTACTCAGTCACCTAAATCTTCTTTCCTGGCAAGCTTGAATCCAAAAACATGGG
GAAGGTTAAGTACACAGTCCAACAGCAACAACATTGAGCCAGCACGGACTGCGGGAGGTAGTGGCCTTGCCAGGGCTGCCTCAAAGGATA
CCATCTCCAATAATAGAGAAAAAATTAAAGGTTGGATTAAGGAGCAGGCACATAAATTTGTAGAACGTTATTTCAGTTCTGAGAATATGG
ATGGAAGCAACCCTGCATTGAATGTCCTTCAGAGACTTTGTGCTGCAACCGAACAACTCAACCTCCAGGTGGATGGTGGAGCTGAGTGCC
TTGTAGAAATCCGTAGCATAGTCTCAGAGTCAGATGTTTCATCATTTGAAATCCAACATAGTGGATTTGTGAAGCAGCTGTTGCTTTATT
TGACATCTAAAAGTGAAAAGGATGCTGTGAGCAGAGAGATCAGATTAAAGCGATTTCTTCATGTATTTTTTTCTTCTCCACTTCCTGGAG
AAGAGCCCATTGGAAGAGTGGAACCAGTGGGTAATGCACCTTTGTTGGCATTAGTTCACAAGATGAACAACTGCCTCAGCCAGATGGAAC
AATTTCCAGTCAAAGTACATGATTTCCCTAGTGGAAATGGGACAGGAGGCAGCTTTTCTCTCAACAGAGGATCACAGGCTTTAAAATTTT
TCAACACACATCAATTAAAATGCCAGTTACAAAGGCATCCAGACTGTGCAAATGTGAAGCAGTGGAAGGGTGGACCTGTCAAGATTGACC
CTCTGGCTTTGGTACAAGCCATCGAGAGATACCTTGTAGTTAGAGGGTATGGAAGAGTAAGAGAAGATGATGAAGACAGCGATGACGATG
GATCAGATGAGGAAATAGATGAGTCTCTGGCTGCTCAGTTCCTAAATTCAGGAAATGTAAGACACAGGCTGCAGTTTTATATTGGAGAAC
ATTTGCTGCCGTATAACATGACTGTGTATCAGGCAGTACGGCAGTTTAGTATACAGGCTGAAGATGAAAGAGAATCCACAGATGATGAGA
GCAATCCTCTAGGCAGAGCTGGTATTTGGACAAAGACTCATACAATATGGTATAAACCTGTGAGAGAGGATGAAGAAAGTAATAAAGATT
GTGTTGGTGGTAAAAGAGGAAGAGCCCAAACAGCTCCAACGAAAACTTCCCCTAGAAATGCAAAAAAGCATGATGAGTTATGGCACGATG
GAGTGTGCCCATCAGTATCAAATCCTTTAGAAGTTTACCTCATTCCCACACCACCTGAAAATATAACATTTGAAGACCCGTCATTAGATG
TGATCCTTCTTTTAAGAGTTTTACATGCTATCAGTCGATACTGGTATTACTTGTATGATAATGCAATGTGCAAGGAAATTATTCCAACTA
GTGAATTTATTAACAGTAAGTTAACAGCAAAAGCAAATAGGCAACTTCAAGATCCTTTAGTAATCATGACAGGAAACATCCCAACATGGC
TTACTGAGCTAGGAAAAACCTGCCCATTTTTCTTTCCTTTTGATACCCGGCAAATGCTTTTTTATGTAACTGCATTTGATCGGGACCGAG
CAATGCAAAGATTACTTGATACCAACCCAGAAATCAACCAGTCTGATTCTCAAGATAGCAGAGTTGCACCTAGATTGGATAGAAAAAAAC
GTACTGTGAACCGAGAGGAGCTGCTGAAACAGGCGGAGTCTGTGATGCAGGACCTCGGCAGCTCACGGGCCATGTTAGAAATCCAGTATG
AAAATGAGGTTGGTACAGGTCTTGGGCCTACACTGGAGTTTTATGCGCTTGTATCTCAGGAACTACAGAGAGCTGACTTGGGTCTTTGGA
GAGGTGAAGAAGTAACTCTTAGCAATCCAAAAGGGAGCCAAGAAGGGACCAAGTATATTCAAAACCTCCAGGGCCTGTTTGCGCTTCCCT
TTGGTAGGACAGCAAAGCCAGCTCATATCGCAAAGGTTAAGATGAAGTTTCGCTTCTTAGGAAAATTAATGGCCAAGGCTATCATGGATT
TCAGATTGGTGGACCTTCCCCTTGGCTTACCCTTTTATAAATGGATGCTACGGCAAGAAACTTCACTGACATCACACGATTTGTTTGACA
TCGACCCAGTTGTAGCCAGATCAGTTTATCACCTAGAAGACATTGTCAGACAGAAGAAAAGACTTGAACAAGATAAATCCCAGCTTGTTG
CAGATCCTTGTGCCAGCAACCCTTGTCACCATGGCAACTGCAGCAGCAGCAGCAGCAGCAGCAGCGATGGCTACCTCTGCATTTGCAATG
AAGGCTATGAAGGTCCCAACTGTGAACAGGCACTTCCCAGTCTCCCAGCCACTGGCTGGACCGAATCCATGGCACCCCGACAGCTTCAGC
CTGTTCCTGCTACTCAGGAGCCTGACAAAATCCTGCCTCGCTCTCAGGCAACGGTGACACTGCCTACCTGGCAGCCGAAAACAGGGCAGA
AAGTTGTAGAAATGAAATGGGATCAAGTGGAGGTGATCCCAGATATTGCCTGTGGGAATGCCAGTTCTAACAGCTCTGCGGGTGGCCGCC
TGGTATCCTTTGAAGTGCCACAGAACACCTCAGTCAAGATTCGGCAAGATGCCACTGCCTCACTGATTTTGCTCTGGAAGGTCACGGCCA
CAGGATTCCAACAGTGCTCCCTCATAGATGGACGAAGTGTGACCCCCCTTCAGGCTTCAGGGGGACTGGTCCTCCTGGAGGAGATGCTCG
CCTTGGGGAATAATCACTTTATTGGTTTTGTGAATGATTCTGTGACTAAGTCTATTGTGGCTTTGCGCTTAACTCTGGTGGTGAAGGTCA
GCACCTGTGTGCCGGGGGAGAGTCACGCAAATGACTTGGAGTGTTCAGGAAAAGGAAAATGCACCACGAAGCCGTCAGAGGCAACTTTTT
CCTGTACCTGTGAGGAGCAGTACGTGGGTACTTTCTGTGAAGAATACGATGCTTGCCAGAGGAAACCTTGCCAAAACAACGCGAGCTGTA
TTGATGCAAATGAAAAGCAAGATGGGAGCAATTTCACCTGTGTTTGCCTTCCTGGTTATACTGGAGAGCTTTGCCAGTCCAAGATTGATT
ACTGCATCCTAGACCCATGCAGAAATGGAGCAACATGCATTTCCAGTCTCAGTGGATTCACCTGCCAGTGTCCAGAAGGATACTTCGGAT
CTGCTTGTGAAGAAAAGGTGGACCCCTGCGCCTCGTCTCCGTGCCAGAACAACGGCACCTGCTATGTGGACGGGGTACACTTTACCTGCA
ACTGCAGCCCGGGCTTCACAGGGCCGACCTGTGCCCAGCTTATTGACTTCTGTGCCCTCAGCCCCTGTGCTCATGGCACGTGCCGCAGCG
TGGGCACCAGCTACAAATGCCTCTGTGATCCAGGTTACCATGGCCTCTACTGTGAGGAGGAATATAATGAGTGCCTCTCCGCTCCATGCC
TGAATGCAGCCACCTGCAGGGACCTCGTTAATGGCTATGAGTGTGTGTGCCTGGCAGAATACAAAGGAACACACTGTGAATTGTACAAGG
ATCCCTGCGCTAACGTCAGCTGTCTGAACGGAGCCACCTGTGACAGCGACGGCCTGAATGGCACGTGCATCTGTGCACCCGGGTTTACAG
GTGAAGAGTGCGACATTGACATAAATGAATGTGACAGTAACCCCTGCCACCATGGTGGGAGCTGCCTGGACCAGCCCAATGGTTATAACT
GCCACTGCCCGCATGGTTGGGTGGGAGCAAACTGTGAGATCCACCTCCAATGGAAGTCCGGGCACATGGCGGAGAGCCTCACCAACATGC
CACGGCACTCCCTCTACATCATCATTGGAGCCCTCTGCGTGGCCTTCATCCTTATGCTGATCATCCTGATCGTGGGGATTTGCCGCATCA
GCCGCATTGAATACCAGGGTTCTTCCAGGCCAGCCTATGAGGAGTTCTACAACTGCCGCAGCATCGACAGCGAGTTCAGCAATGCCATTG
CATCCATCCGGCATGCCAGGTTTGGAAAGAAATCCCGGCCTGCAATGTATGATGTGAGCCCCATCGCCTATGAAGATTACAGTCCTGATG
ACAAACCCTTGGTCACACTGATTAAAACTAAAGATTTGTAATCTTTTTTTGGATTATTTTTCAAAAAGATGAGATACTACACTCATTTAA
ATATTTTTAAGAAAATAAAAAGCTTAAGAAATTTAAAATGCTAGCTGCTCAAGAGTTTTCAGTAGAATATTTAAGAACTAATTTTCTGCA
GCTTTTAGTTTGGAAAAAATATTTTAAAAACAAAATTTGTGAAACCTATAGACGATGTTTTAATGTACCTTCAGCTCTCTAAACTGTGTG
CTTCTACTAGTGTGTGCTCTTTTCACTGTAGACACTATCACGAGACCCAGATTAATTTCTGTGGTTGTTACAGAATAAGTCTAATCAAGG
AGAAGTTTCTGTTTGACGTTTGAGTGCCGGCTTTCTGAGTAGAGTTAGGAAAACCACGTAACGTAGCATATGATGTATAATAGAGTATAC
CCGTTACTTAAAAAGAAGTCTGAAATGTTCGTTTTGTGGAAAAGAAACTAGTTAAATTTACTATTCCTAACCCGAATGAAATTAGCCTTT
GCCTTATTCTGTGCATGGGTAAGTAACTTATTTCTGCACTGTTTTGTTGAACTTTGTGGAAACATTCTTTCGAGTTTGTTTTTGTCATTT
TCGTAACAGTCGTCGAACTAGGCCTCAAAAACATACGTAACGAAAAGGCCTAGCGAGGCAAATTCTGATTGATTTGAATCTATATTTTTC
TTTAAAAAGTCAAGGGTTCTATATTGTGAGTAAATTAAATTTACATTTGAGTTGTTTGTTGCTAAGAGGTAGTAAATGTAAGAGAGTACT
GGTTCCTTCAGTAGTGAGTATTTCTCATAGTGCAGCTTTATTTATCTCCAGGATGTTTTTGTGGCTGTATTTGATTGATATGTGCTTCTT

>94239_94239_1_TRIP12-DNER_TRIP12_chr2_230642030_ENST00000283943_DNER_chr2_230456604_ENST00000341772_length(amino acids)=2413AA_BP=0
MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGRSCSSSSAVIVPQPEDPDRANTSERQKTGQVPKKDNSRGVKRSASPDYNRTNSPSSAK
KPKALQHTESPSETNKPHSKSKKRHLDQEQQLKSAQSPSTSKAHTRKSGATGGSRSQKRKRTESSCVKSGSGSESTGAEERSAKPTKLAS
KSATSAKAGCSTITDSSSAASTSSSSSAVASASSTVPPGARVKQGKDQNKARRSRSASSPSPRRSSREKEQSKTGGSSKFDWAARFSPKV
SLPKTKLSLPGSSKSETSKPGPSGLQAKLASLRKSTKKRSESPPAELPSLRRSTRQKTTGSCASTSRRGSGLGKRGAAEARRQEKMADPE
SNQEAVNSSAARTDEAPQGAAGAVGMTTSGESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQASD
ESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVDAIPVFLEKLQVIQCIDVAE
QALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLV
DNFQHEENLLQQVASKDLLTNVQQLLVVTPPILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCGASNGSCQEQIDLVPRS
PQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIEQINEDTGTARAIQRKPNPLANSNTSG
YSESKKDDARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIASMLSSQDLKIVV
GALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAESESLLTSPPKACTNGSGSMGSTTSVSSGTATAATHAAADLGSPSLQHSRDDSLDL
SPQGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKSPTTTQSPKSSFLASLNPKTWGRLSTQSNSNNIEPARTAGGSGLARAASKD
TISNNREKIKGWIKEQAHKFVERYFSSENMDGSNPALNVLQRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLY
LTSKSEKDAVSREIRLKRFLHVFFSSPLPGEEPIGRVEPVGNAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGTGGSFSLNRGSQALKF
FNTHQLKCQLQRHPDCANVKQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGE
HLLPYNMTVYQAVRQFSIQAEDERESTDDESNPLGRAGIWTKTHTIWYKPVREDEESNKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHD
GVCPSVSNPLEVYLIPTPPENITFEDPSLDVILLLRVLHAISRYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTW
LTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNPEINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQY
ENEVGTGLGPTLEFYALVSQELQRADLGLWRGEEVTLSNPKGSQEGTKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMD
FRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQLVADPCASNPCHHGNCSSSSSSSSDGYLCICN
EGYEGPNCEQALPSLPATGWTESMAPRQLQPVPATQEPDKILPRSQATVTLPTWQPKTGQKVVEMKWDQVEVIPDIACGNASSNSSAGGR
LVSFEVPQNTSVKIRQDATASLILLWKVTATGFQQCSLIDGRSVTPLQASGGLVLLEEMLALGNNHFIGFVNDSVTKSIVALRLTLVVKV
STCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID
YCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRS
VGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFT
GEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSGHMAESLTNMPRHSLYIIIGALCVAFILMLIILIVGICRI

--------------------------------------------------------------
>94239_94239_2_TRIP12-DNER_TRIP12_chr2_230642030_ENST00000389044_DNER_chr2_230456604_ENST00000341772_length(transcript)=8466nt_BP=5617nt
AGCTGATAATTGAAGGAACCCGGAGCCGCCGCCGCCGCGCCGCTGGGGGGGGTGGGGGGAGCTAGTGGAAGTTACTGCCGCGCCACCGAG
TCCGGACCGGAGACTTTGGGGCCTAACTAGTGAATGGTAGTGTCTAGAAAGGGTATGTCCCTTCAAGAGAGAGGTGCCAATGTCCAACCG
GCCTAATAACAATCCAGGGGGGTCACTGCGACGTTCACAGAGGAACACTGCCGGGGCCCAACCACAAGACGACTCAATAGGAGGAAGGTC
ACATTTAGGGCAGGCAAAACATAAGGGATATAGCCCTCCTGAGAGTAGAAAATCTAATTCTAAGGCACCCAAAGTGCAGTCTAATACTAC
TTCTGAACTGTCAAGGGGACACCTTTCTAAAAGAAGCTGCAGTTCATCATCTGCTGTGATAGTTCCACAACCAGAGGATCCAGACAGAGC
CAATACTTCAGAAAGACAAAAAACGGGGCAGGTGCCTAAGAAAGACAATTCTCGAGGAGTGAAGCGCAGTGCTAGTCCAGACTACAACAG
GACCAATTCTCCTAGCTCTGCAAAAAAACCAAAAGCACTTCAGCATACTGAATCTCCCTCAGAAACAAATAAGCCACATAGTAAGTCAAA
GAAGAGACATTTAGACCAGGAGCAACAACTGAAATCTGCACAATCACCATCAACAAGCAAGGCTCATACCAGGAAGAGTGGGGCCACTGG
CGGTTCACGGAGTCAGAAAAGAAAAAGGACAGAGAGTTCTTGTGTAAAGAGTGGCTCCGGGTCTGAATCAACTGGTGCAGAAGAGAGATC
TGCGAAACCTACCAAGCTGGCTTCAAAATCAGCCACCTCAGCCAAAGCTGGGTGTAGCACCATCACTGATTCTTCTTCTGCTGCCTCTAC
TTCCTCCTCGTCTTCTGCTGTAGCCTCGGCCTCCTCCACTGTACCACCAGGTGCCAGAGTGAAACAAGGAAAAGATCAGAACAAGGCCAG
GCGTTCCCGTTCAGCGTCCAGTCCCAGCCCCAGAAGAAGTAGCAGGGAAAAGGAACAGAGTAAAACTGGTGGCTCTTCAAAATTTGATTG
GGCTGCTCGTTTCAGCCCTAAAGTTAGCCTTCCTAAAACAAAACTGTCTCTTCCAGGGTCTTCTAAGTCAGAGACATCAAAACCTGGACC
TTCTGGATTACAGGCCAAATTAGCAAGTTTAAGAAAATCTACGAAGAAACGCAGTGAGTCTCCACCTGCTGAGCTCCCCAGTTTGAGGCG
GAGCACACGCCAAAAGACCACGGGCTCCTGTGCTAGTACCAGTCGGCGAGGCTCTGGCCTGGGCAAAAGAGGAGCAGCTGAAGCTCGTCG
ACAGGAGAAAATGGCAGACCCTGAAAGCAACCAGGAGGCAGTAAATTCTTCAGCTGCTCGGACAGATGAAGCTCCCCAAGGAGCTGCAGC
CTCTAGTTCTGTTGCAGGGGCTGTTGGCATGACCACCTCTGGGGAGAGTGAATCAGATGATTCCGAGATGGGACGTTTGCAAGCTTTGTT
AGAGGCAAGGGGTCTTCCCCCTCACCTATTTGGTCCTCTTGGTCCTCGGATGTCACAGCTTTTCCATAGAACAATTGGAAGTGGAGCTAG
TTCTAAGGCCCAGCAGCTACTACAAGGATTGCAAGCCAGTGATGAAAGTCAACAGCTTCAGGCAGTTATTGAGATGTGTCAGTTACTGGT
CATGGGAAATGAGGAGACACTGGGAGGGTTTCCTGTCAAGAGTGTTGTTCCAGCTTTGATTACGTTACTTCAGATGGAGCACAATTTTGA
TATTATGAACCATGCTTGTCGAGCCTTAACATACATGATGGAAGCACTTCCTCGATCTTCTGCTGTTGTAGTAGATGCTATTCCTGTCTT
TTTAGAAAAGCTGCAAGTTATTCAGTGTATTGATGTGGCAGAGCAGGCCTTGACTGCCTTGGAGATGTTGTCACGGAGACATAGTAAAGC
CATTCTACAGGCGGGTGGTTTGGCAGACTGCTTGCTGTACCTAGAATTCTTCAGCATAAATGCCCAAAGAAATGCATTAGCAATTGCAGC
TAATTGCTGCCAGAGTATCACGCCAGATGAATTTCATTTTGTGGCAGATTCACTCCCATTGCTAACCCAAAGGCTAACACATCAGGATAA
AAAGTCAGTAGAAAGCACTTGCCTTTGTTTTGCACGCCTAGTGGACAACTTCCAGCATGAGGAGAATTTACTCCAGCAGGTTGCTTCCAA
AGATCTGCTTACAAATGTTCAACAGCTGTTGGTAGTGACTCCACCCATTTTAAGTTCTGGGATGTTTATAATGGTGGTTCGCATGTTTTC
TCTGATGTGTTCCAACTGTCCAACTTTAGCTGTTCAACTTATGAAACAAAACATTGCAGAAACGCTTCACTTTCTCCTGTGTGGTGCCTC
CAATGGAAGTTGTCAGGAACAGATTGATCTTGTTCCACGAAGCCCTCAAGAGTTGTATGAACTGACATCTCTGATTTGTGAACTTATGCC
ATGTTTACCAAAAGAAGGCATTTTTGCAGTTGATACCATGTTGAAGAAGGGAAATGCACAGAACACAGATGGTGCGATATGGCAGTGGCG
TGATGATCGGGGCCTCTGGCATCCATATAACAGGATTGACAGCCGGATCATTGAGCAAATCAATGAGGACACGGGAACAGCACGTGCCAT
TCAGAGAAAACCTAACCCGTTAGCCAATAGTAACACTAGTGGATATTCAGAGTCAAAGAAGGATGATGCTCGAGCACAGCTTATGAAAGA
GGATCCGGAACTGGCTAAGTCTTTTATTAAGACATTATTTGGTGTTCTTTATGAAGTGTATAGTTCCTCAGCAGGACCTGCGGTCAGACA
TAAGTGCCTTAGAGCAATTCTTAGGATAATTTATTTTGCGGATGCTGAACTTCTGAAGGATGTTCTGAAAAATCATGCTGTTTCAAGTCA
CATTGCTTCCATGCTGTCAAGCCAAGACCTGAAGATAGTAGTGGGAGCACTTCAGATGGCAGAAATTTTAATGCAGAAGTTACCTGATAT
TTTTAGTGTTTACTTCAGAAGAGAAGGTGTAATGCATCAAGTAAAACACTTAGCAGAATCAGAGTCTTTGTTGACAAGTCCACCAAAGGC
ATGTACGAATGGATCGGGATCCATGGGATCCACAACTTCAGTCAGCAGTGGGACAGCCACAGCTGCCACTCATGCTGCAGCTGACTTGGG
ATCACCCAGCTTGCAGCACAGCAGGGATGATTCTTTAGATCTCAGCCCTCAAGGTCGATTAAGTGATGTTCTAAAGAGAAAACGACTGCC
AAAACGAGGGCCAAGAAGGCCAAAGTACTCACCTCCAAGAGATGATGACAAAGTAGACAATCAAGCTAAAAGCCCCACCACTACTCAGTC
ACCTAAATCTTCTTTCCTGGCAAGCTTGAATCCAAAAACATGGGGAAGGTTAAGTACACAGTCCAACAGCAACAACATTGAGCCAGCACG
GACTGCGGGAGGTAGTGGCCTTGCCAGGGCTGCCTCAAAGGATACCATCTCCAATAATAGAGAAAAAATTAAAGGTTGGATTAAGGAGCA
GGCACATAAATTTGTAGAACGTTATTTCAGTTCTGAGAATATGGATGGAAGCAACCCTGCATTGAATGTCCTTCAGAGACTTTGTGCTGC
AACCGAACAACTCAACCTCCAGGTGGATGGTGGAGCTGAGTGCCTTGTAGAAATCCGTAGCATAGTCTCAGAGTCAGATGTTTCATCATT
TGAAATCCAACATAGTGGATTTGTGAAGCAGCTGTTGCTTTATTTGACATCTAAAAGTGAAAAGGATGCTGTGAGCAGAGAGATCAGATT
AAAGCGATTTCTTCATGTATTTTTTTCTTCTCCACTTCCTGGAGAAGAGCCCATTGGAAGAGTGGAACCAGTGGGTAATGCACCTTTGTT
GGCATTAGTTCACAAGATGAACAACTGCCTCAGCCAGATGGAACAATTTCCAGTCAAAGTACATGATTTCCCTAGTGGAAATGGGACAGG
AGGCAGCTTTTCTCTCAACAGAGGATCACAGGCTTTAAAATTTTTCAACACACATCAATTAAAATGCCAGTTACAAAGGCATCCAGACTG
TGCAAATGTGAAGCAGTGGAAGGGTGGACCTGTCAAGATTGACCCTCTGGCTTTGGTACAAGCCATCGAGAGATACCTTGTAGTTAGAGG
GTATGGAAGAGTAAGAGAAGATGATGAAGACAGCGATGACGATGGATCAGATGAGGAAATAGATGAGTCTCTGGCTGCTCAGTTCCTAAA
TTCAGGAAATGTAAGACACAGGCTGCAGTTTTATATTGGAGAACATTTGCTGCCGTATAACATGACTGTGTATCAGGCAGTACGGCAGTT
TAGTATACAGGCTGAAGATGAAAGAGAATCCACAGATGATGAGAGCAATCCTCTAGGCAGAGCTGGTATTTGGACAAAGACTCATACAAT
ATGGTATAAACCTGTGAGAGAGGATGAAGAAAGTAATAAAGATTGTGTTGGTGGTAAAAGAGGAAGAGCCCAAACAGCTCCAACGAAAAC
TTCCCCTAGAAATGCAAAAAAGCATGATGAGTTATGGCACGATGGAGTGTGCCCATCAGTATCAAATCCTTTAGAAGTTTACCTCATTCC
CACACCACCTGAAAATATAACATTTGAAGACCCGTCATTAGATGTGATCCTTCTTTTAAGAGTTTTACATGCTATCAGTCGATACTGGTA
TTACTTGTATGATAATGCAATGTGCAAGGAAATTATTCCAACTAGTGAATTTATTAACAGTAAGTTAACAGCAAAAGCAAATAGGCAACT
TCAAGATCCTTTAGTAATCATGACAGGAAACATCCCAACATGGCTTACTGAGCTAGGAAAAACCTGCCCATTTTTCTTTCCTTTTGATAC
CCGGCAAATGCTTTTTTATGTAACTGCATTTGATCGGGACCGAGCAATGCAAAGATTACTTGATACCAACCCAGAAATCAACCAGTCTGA
TTCTCAAGATAGCAGAGTTGCACCTAGATTGGATAGAAAAAAACGTACTGTGAACCGAGAGGAGCTGCTGAAACAGGCGGAGTCTGTGAT
GCAGGACCTCGGCAGCTCACGGGCCATGTTAGAAATCCAGTATGAAAATGAGGTTGGTACAGGTCTTGGGCCTACACTGGAGTTTTATGC
GCTTGTATCTCAGGAACTACAGAGAGCTGACTTGGGTCTTTGGAGAGGTGAAGAAGTAACTCTTAGCAATCCAAAAGGGAGCCAAGAAGG
GACCAAGTATATTCAAAACCTCCAGGGCCTGTTTGCGCTTCCCTTTGGTAGGACAGCAAAGCCAGCTCATATCGCAAAGGTTAAGATGAA
GTTTCGCTTCTTAGGAAAATTAATGGCCAAGGCTATCATGGATTTCAGATTGGTGGACCTTCCCCTTGGCTTACCCTTTTATAAATGGAT
GCTACGGCAAGAAACTTCACTGACATCACACGATTTGTTTGACATCGACCCAGTTGTAGCCAGATCAGTTTATCACCTAGAAGACATTGT
CAGACAGAAGAAAAGACTTGAACAAGATAAATCCCAGCTTGTTGCAGATCCTTGTGCCAGCAACCCTTGTCACCATGGCAACTGCAGCAG
CAGCAGCAGCAGCAGCAGCGATGGCTACCTCTGCATTTGCAATGAAGGCTATGAAGGTCCCAACTGTGAACAGGCACTTCCCAGTCTCCC
AGCCACTGGCTGGACCGAATCCATGGCACCCCGACAGCTTCAGCCTGTTCCTGCTACTCAGGAGCCTGACAAAATCCTGCCTCGCTCTCA
GGCAACGGTGACACTGCCTACCTGGCAGCCGAAAACAGGGCAGAAAGTTGTAGAAATGAAATGGGATCAAGTGGAGGTGATCCCAGATAT
TGCCTGTGGGAATGCCAGTTCTAACAGCTCTGCGGGTGGCCGCCTGGTATCCTTTGAAGTGCCACAGAACACCTCAGTCAAGATTCGGCA
AGATGCCACTGCCTCACTGATTTTGCTCTGGAAGGTCACGGCCACAGGATTCCAACAGTGCTCCCTCATAGATGGACGAAGTGTGACCCC
CCTTCAGGCTTCAGGGGGACTGGTCCTCCTGGAGGAGATGCTCGCCTTGGGGAATAATCACTTTATTGGTTTTGTGAATGATTCTGTGAC
TAAGTCTATTGTGGCTTTGCGCTTAACTCTGGTGGTGAAGGTCAGCACCTGTGTGCCGGGGGAGAGTCACGCAAATGACTTGGAGTGTTC
AGGAAAAGGAAAATGCACCACGAAGCCGTCAGAGGCAACTTTTTCCTGTACCTGTGAGGAGCAGTACGTGGGTACTTTCTGTGAAGAATA
CGATGCTTGCCAGAGGAAACCTTGCCAAAACAACGCGAGCTGTATTGATGCAAATGAAAAGCAAGATGGGAGCAATTTCACCTGTGTTTG
CCTTCCTGGTTATACTGGAGAGCTTTGCCAGTCCAAGATTGATTACTGCATCCTAGACCCATGCAGAAATGGAGCAACATGCATTTCCAG
TCTCAGTGGATTCACCTGCCAGTGTCCAGAAGGATACTTCGGATCTGCTTGTGAAGAAAAGGTGGACCCCTGCGCCTCGTCTCCGTGCCA
GAACAACGGCACCTGCTATGTGGACGGGGTACACTTTACCTGCAACTGCAGCCCGGGCTTCACAGGGCCGACCTGTGCCCAGCTTATTGA
CTTCTGTGCCCTCAGCCCCTGTGCTCATGGCACGTGCCGCAGCGTGGGCACCAGCTACAAATGCCTCTGTGATCCAGGTTACCATGGCCT
CTACTGTGAGGAGGAATATAATGAGTGCCTCTCCGCTCCATGCCTGAATGCAGCCACCTGCAGGGACCTCGTTAATGGCTATGAGTGTGT
GTGCCTGGCAGAATACAAAGGAACACACTGTGAATTGTACAAGGATCCCTGCGCTAACGTCAGCTGTCTGAACGGAGCCACCTGTGACAG
CGACGGCCTGAATGGCACGTGCATCTGTGCACCCGGGTTTACAGGTGAAGAGTGCGACATTGACATAAATGAATGTGACAGTAACCCCTG
CCACCATGGTGGGAGCTGCCTGGACCAGCCCAATGGTTATAACTGCCACTGCCCGCATGGTTGGGTGGGAGCAAACTGTGAGATCCACCT
CCAATGGAAGTCCGGGCACATGGCGGAGAGCCTCACCAACATGCCACGGCACTCCCTCTACATCATCATTGGAGCCCTCTGCGTGGCCTT
CATCCTTATGCTGATCATCCTGATCGTGGGGATTTGCCGCATCAGCCGCATTGAATACCAGGGTTCTTCCAGGCCAGCCTATGAGGAGTT
CTACAACTGCCGCAGCATCGACAGCGAGTTCAGCAATGCCATTGCATCCATCCGGCATGCCAGGTTTGGAAAGAAATCCCGGCCTGCAAT
GTATGATGTGAGCCCCATCGCCTATGAAGATTACAGTCCTGATGACAAACCCTTGGTCACACTGATTAAAACTAAAGATTTGTAATCTTT
TTTTGGATTATTTTTCAAAAAGATGAGATACTACACTCATTTAAATATTTTTAAGAAAATAAAAAGCTTAAGAAATTTAAAATGCTAGCT
GCTCAAGAGTTTTCAGTAGAATATTTAAGAACTAATTTTCTGCAGCTTTTAGTTTGGAAAAAATATTTTAAAAACAAAATTTGTGAAACC
TATAGACGATGTTTTAATGTACCTTCAGCTCTCTAAACTGTGTGCTTCTACTAGTGTGTGCTCTTTTCACTGTAGACACTATCACGAGAC
CCAGATTAATTTCTGTGGTTGTTACAGAATAAGTCTAATCAAGGAGAAGTTTCTGTTTGACGTTTGAGTGCCGGCTTTCTGAGTAGAGTT
AGGAAAACCACGTAACGTAGCATATGATGTATAATAGAGTATACCCGTTACTTAAAAAGAAGTCTGAAATGTTCGTTTTGTGGAAAAGAA
ACTAGTTAAATTTACTATTCCTAACCCGAATGAAATTAGCCTTTGCCTTATTCTGTGCATGGGTAAGTAACTTATTTCTGCACTGTTTTG
TTGAACTTTGTGGAAACATTCTTTCGAGTTTGTTTTTGTCATTTTCGTAACAGTCGTCGAACTAGGCCTCAAAAACATACGTAACGAAAA
GGCCTAGCGAGGCAAATTCTGATTGATTTGAATCTATATTTTTCTTTAAAAAGTCAAGGGTTCTATATTGTGAGTAAATTAAATTTACAT
TTGAGTTGTTTGTTGCTAAGAGGTAGTAAATGTAAGAGAGTACTGGTTCCTTCAGTAGTGAGTATTTCTCATAGTGCAGCTTTATTTATC
TCCAGGATGTTTTTGTGGCTGTATTTGATTGATATGTGCTTCTTCTGATTCTTGCTAATTTCCAACCATATTGAATAAATGTGATCAAGT

>94239_94239_2_TRIP12-DNER_TRIP12_chr2_230642030_ENST00000389044_DNER_chr2_230456604_ENST00000341772_length(amino acids)=2461AA_BP=0
MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGRSHLGQAKHKGYSPPESRKSNSKAPKVQSNTTSELSRGHLSKRSCSSSSAVIVPQPED
PDRANTSERQKTGQVPKKDNSRGVKRSASPDYNRTNSPSSAKKPKALQHTESPSETNKPHSKSKKRHLDQEQQLKSAQSPSTSKAHTRKS
GATGGSRSQKRKRTESSCVKSGSGSESTGAEERSAKPTKLASKSATSAKAGCSTITDSSSAASTSSSSSAVASASSTVPPGARVKQGKDQ
NKARRSRSASSPSPRRSSREKEQSKTGGSSKFDWAARFSPKVSLPKTKLSLPGSSKSETSKPGPSGLQAKLASLRKSTKKRSESPPAELP
SLRRSTRQKTTGSCASTSRRGSGLGKRGAAEARRQEKMADPESNQEAVNSSAARTDEAPQGAAASSSVAGAVGMTTSGESESDDSEMGRL
QALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQASDESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQME
HNFDIMNHACRALTYMMEALPRSSAVVVDAIPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNAL
AIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLVVTPPILSSGMFIMVV
RMFSLMCSNCPTLAVQLMKQNIAETLHFLLCGASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAI
WQWRDDRGLWHPYNRIDSRIIEQINEDTGTARAIQRKPNPLANSNTSGYSESKKDDARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGP
AVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIASMLSSQDLKIVVGALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAESESLLTS
PPKACTNGSGSMGSTTSVSSGTATAATHAAADLGSPSLQHSRDDSLDLSPQGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKSPT
TTQSPKSSFLASLNPKTWGRLSTQSNSNNIEPARTAGGSGLARAASKDTISNNREKIKGWIKEQAHKFVERYFSSENMDGSNPALNVLQR
LCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKSEKDAVSREIRLKRFLHVFFSSPLPGEEPIGRVEPVGN
APLLALVHKMNNCLSQMEQFPVKVHDFPSGNGTGGSFSLNRGSQALKFFNTHQLKCQLQRHPDCANVKQWKGGPVKIDPLALVQAIERYL
VVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGEHLLPYNMTVYQAVRQFSIQAEDERESTDDESNPLGRAGIWTK
THTIWYKPVREDEESNKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHDGVCPSVSNPLEVYLIPTPPENITFEDPSLDVILLLRVLHAIS
RYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNPEI
NQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLGLWRGEEVTLSNPKG
SQEGTKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHL
EDIVRQKKRLEQDKSQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLPATGWTESMAPRQLQPVPATQEPDKIL
PRSQATVTLPTWQPKTGQKVVEMKWDQVEVIPDIACGNASSNSSAGGRLVSFEVPQNTSVKIRQDATASLILLWKVTATGFQQCSLIDGR
SVTPLQASGGLVLLEEMLALGNNHFIGFVNDSVTKSIVALRLTLVVKVSTCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTF
CEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCAS
SPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNG
YECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANC
EIHLQWKSGHMAESLTNMPRHSLYIIIGALCVAFILMLIILIVGICRISRIEYQGSSRPAYEEFYNCRSIDSEFSNAIASIRHARFGKKS

--------------------------------------------------------------
>94239_94239_3_TRIP12-DNER_TRIP12_chr2_230642030_ENST00000389045_DNER_chr2_230456604_ENST00000341772_length(transcript)=7416nt_BP=4567nt
CCGGAGACTTTGGGGCCTAACTAGTGAATGGTAGTGTCTAGAAAGGGTATGTCCCTTCAAGAGAGAGGTGCCAATGTCCAACCGGCCTAA
TAACAATCCAGGGGGGTCACTGCGACGTTCACAGAGGAACACTGCCGGGGCCCAACCACAAGACGACTCAATAGGAGGAAGTCGGCGAGG
CTCTGGCCTGGGCAAAAGAGGAGCAGCTGAAGCTCGTCGACAGGAGAAAATGGCAGACCCTGAAAGCAACCAGGAGGCAGTAAATTCTTC
AGCTGCTCGGACAGATGAAGCTCCCCAAGGAGCTGCAGCCTCTAGTTCTGTTGCAGGGGCTGTTGGCATGACCACCTCTGGGGAGAGTGA
ATCAGATGATTCCGAGATGGGACGTTTGCAAGCTTTGTTAGAGGCAAGGGGTCTTCCCCCTCACCTATTTGGTCCTCTTGGTCCTCGGAT
GTCACAGCTTTTCCATAGAACAATTGGAAGTGGAGCTAGTTCTAAGGCCCAGCAGCTACTACAAGGATTGCAAGCCAGTGATGAAAGTCA
ACAGCTTCAGGCAGTTATTGAGATGTGTCAGTTACTGGTCATGGGAAATGAGGAGACACTGGGAGGGTTTCCTGTCAAGAGTGTTGTTCC
AGCTTTGATTACGTTACTTCAGATGGAGCACAATTTTGATATTATGAACCATGCTTGTCGAGCCTTAACATACATGATGGAAGCACTTCC
TCGATCTTCTGCTGTTGTAGTAGATGCTATTCCTGTCTTTTTAGAAAAGCTGCAAGTTATTCAGTGTATTGATGTGGCAGAGCAGGCCTT
GACTGCCTTGGAGATGTTGTCACGGAGACATAGTAAAGCCATTCTACAGGCGGGTGGTTTGGCAGACTGCTTGCTGTACCTAGAATTCTT
CAGCATAAATGCCCAAAGAAATGCATTAGCAATTGCAGCTAATTGCTGCCAGAGTATCACGCCAGATGAATTTCATTTTGTGGCAGATTC
ACTCCCATTGCTAACCCAAAGGCTAACACATCAGGATAAAAAGTCAGTAGAAAGCACTTGCCTTTGTTTTGCACGCCTAGTGGACAACTT
CCAGCATGAGGAGAATTTACTCCAGCAGGTTGCTTCCAAAGATCTGCTTACAAATGTTCAACAGCTGTTGGTAGTGACTCCACCCATTTT
AAGTTCTGGGATGTTTATAATGGTGGTTCGCATGTTTTCTCTGATGTGTTCCAACTGTCCAACTTTAGCTGTTCAACTTATGAAACAAAA
CATTGCAGAAACGCTTCACTTTCTCCTGTGTGGTGCCTCCAATGGAAGTTGTCAGGAACAGATTGATCTTGTTCCACGAAGCCCTCAAGA
GTTGTATGAACTGACATCTCTGATTTGTGAACTTATGCCATGTTTACCAAAAGAAGGCATTTTTGCAGTTGATACCATGTTGAAGAAGGG
AAATGCACAGAACACAGATGGTGCGATATGGCAGTGGCGTGATGATCGGGGCCTCTGGCATCCATATAACAGGATTGACAGCCGGATCAT
TGAGGCAGCCCATCAGGTCGGTGAGGATGAGATAAGCTTGTCCACTCTGGGACGAGTTTATACTATTGATTTTAATTCTATGCAGCAAAT
CAATGAGGACACGGGAACAGCACGTGCCATTCAGAGAAAACCTAACCCGTTAGCCAATAGTAACACTAGTGGATATTCAGAGTCAAAGAA
GGATGATGCTCGAGCACAGCTTATGAAAGAGGATCCGGAACTGGCTAAGTCTTTTATTAAGACATTATTTGGTGTTCTTTATGAAGTGTA
TAGTTCCTCAGCAGGACCTGCGGTCAGACATAAGTGCCTTAGAGCAATTCTTAGGATAATTTATTTTGCGGATGCTGAACTTCTGAAGGA
TGTTCTGAAAAATCATGCTGTTTCAAGTCACATTGCTTCCATGCTGTCAAGCCAAGACCTGAAGATAGTAGTGGGAGCACTTCAGATGGC
AGAAATTTTAATGCAGAAGTTACCTGATATTTTTAGTGTTTACTTCAGAAGAGAAGGTGTAATGCATCAAGTAAAACACTTAGCAGAATC
AGAGTCTTTGTTGACAAGTCCACCAAAGGCATGTACGAATGGATCGGGATCCATGGGATCCACAACTTCAGTCAGCAGTGGGACAGCCAC
AGCTGCCACTCATGCTGCAGCTGACTTGGGATCACCCAGCTTGCAGCACAGCAGGGATGATTCTTTAGATCTCAGCCCTCAAGGTCGATT
AAGTGATGTTCTAAAGAGAAAACGACTGCCAAAACGAGGGCCAAGAAGGCCAAAGTACTCACCTCCAAGAGATGATGACAAAGTAGACAA
TCAAGCTAAAAGCCCCACCACTACTCAGTCACCTAAATCTTCTTTCCTGGCAAGCTTGAATCCAAAAACATGGGGAAGGTTAAGTACACA
GTCCAACAGCAACAACATTGAGCCAGCACGGACTGCGGGAGGTAGTGGCCTTGCCAGGGCTGCCTCAAAGGATACCATCTCCAATAATAG
AGAAAAAATTAAAGGTTGGATTAAGGAGCAGGCACATAAATTTGTAGAACGTTATTTCAGTTCTGAGAATATGGATGGAAGCAACCCTGC
ATTGAATGTCCTTCAGAGACTTTGTGCTGCAACCGAACAACTCAACCTCCAGGTGGATGGTGGAGCTGAGTGCCTTGTAGAAATCCGTAG
CATAGTCTCAGAGTCAGATGTTTCATCATTTGAAATCCAACATAGTGGATTTGTGAAGCAGCTGTTGCTTTATTTGACATCTAAAAGTGA
AAAGGATGCTGTGAGCAGAGAGATCAGATTAAAGCGATTTCTTCATGTATTTTTTTCTTCTCCACTTCCTGGAGAAGAGCCCATTGGAAG
AGTGGAACCAGTGGGTAATGCACCTTTGTTGGCATTAGTTCACAAGATGAACAACTGCCTCAGCCAGATGGAACAATTTCCAGTCAAAGT
ACATGATTTCCCTAGTGGAAATGGGACAGGAGGCAGCTTTTCTCTCAACAGAGGATCACAGGCTTTAAAATTTTTCAACACACATCAATT
AAAATGCCAGTTACAAAGGCATCCAGACTGTGCAAATGTGAAGCAGTGGAAGGGTGGACCTGTCAAGATTGACCCTCTGGCTTTGGTACA
AGCCATCGAGAGATACCTTGTAGTTAGAGGGTATGGAAGAGTAAGAGAAGATGATGAAGACAGCGATGACGATGGATCAGATGAGGAAAT
AGATGAGTCTCTGGCTGCTCAGTTCCTAAATTCAGGAAATGTAAGACACAGGCTGCAGTTTTATATTGGAGAACATTTGCTGCCGTATAA
CATGACTGTGTATCAGGCAGTACGGCAGTTTAGTATACAGGCTGAAGATGAAAGAGAATCCACAGATGATGAGAGCAATCCTCTAGGCAG
AGCTGGTATTTGGACAAAGACTCATACAATATGGTATAAACCTGTGAGAGAGGATGAAGAAAGTAATAAAGATTGTGTTGGTGGTAAAAG
AGGAAGAGCCCAAACAGCTCCAACGAAAACTTCCCCTAGAAATGCAAAAAAGCATGATGAGTTATGGCACGATGGAGTGTGCCCATCAGT
ATCAAATCCTTTAGAAGTTTACCTCATTCCCACACCACCTGAAAATATAACATTTGAAGACCCGTCATTAGATGTGATCCTTCTTTTAAG
AGTTTTACATGCTATCAGTCGATACTGGTATTACTTGTATGATAATGCAATGTGCAAGGAAATTATTCCAACTAGTGAATTTATTAACAG
TAAGTTAACAGCAAAAGCAAATAGGCAACTTCAAGATCCTTTAGTAATCATGACAGGAAACATCCCAACATGGCTTACTGAGCTAGGAAA
AACCTGCCCATTTTTCTTTCCTTTTGATACCCGGCAAATGCTTTTTTATGTAACTGCATTTGATCGGGACCGAGCAATGCAAAGATTACT
TGATACCAACCCAGAAATCAACCAGTCTGATTCTCAAGATAGCAGAGTTGCACCTAGATTGGATAGAAAAAAACGTACTGTGAACCGAGA
GGAGCTGCTGAAACAGGCGGAGTCTGTGATGCAGGACCTCGGCAGCTCACGGGCCATGTTAGAAATCCAGTATGAAAATGAGGTTGGTAC
AGGTCTTGGGCCTACACTGGAGTTTTATGCGCTTGTATCTCAGGAACTACAGAGAGCTGACTTGGGTCTTTGGAGAGGTGAAGAAGTAAC
TCTTAGCAATCCAAAAGGGAGCCAAGAAGGGACCAAGTATATTCAAAACCTCCAGGGCCTGTTTGCGCTTCCCTTTGGTAGGACAGCAAA
GCCAGCTCATATCGCAAAGGTTAAGATGAAGTTTCGCTTCTTAGGAAAATTAATGGCCAAGGCTATCATGGATTTCAGATTGGTGGACCT
TCCCCTTGGCTTACCCTTTTATAAATGGATGCTACGGCAAGAAACTTCACTGACATCACACGATTTGTTTGACATCGACCCAGTTGTAGC
CAGATCAGTTTATCACCTAGAAGACATTGTCAGACAGAAGAAAAGACTTGAACAAGATAAATCCCAGCTTGTTGCAGATCCTTGTGCCAG
CAACCCTTGTCACCATGGCAACTGCAGCAGCAGCAGCAGCAGCAGCAGCGATGGCTACCTCTGCATTTGCAATGAAGGCTATGAAGGTCC
CAACTGTGAACAGGCACTTCCCAGTCTCCCAGCCACTGGCTGGACCGAATCCATGGCACCCCGACAGCTTCAGCCTGTTCCTGCTACTCA
GGAGCCTGACAAAATCCTGCCTCGCTCTCAGGCAACGGTGACACTGCCTACCTGGCAGCCGAAAACAGGGCAGAAAGTTGTAGAAATGAA
ATGGGATCAAGTGGAGGTGATCCCAGATATTGCCTGTGGGAATGCCAGTTCTAACAGCTCTGCGGGTGGCCGCCTGGTATCCTTTGAAGT
GCCACAGAACACCTCAGTCAAGATTCGGCAAGATGCCACTGCCTCACTGATTTTGCTCTGGAAGGTCACGGCCACAGGATTCCAACAGTG
CTCCCTCATAGATGGACGAAGTGTGACCCCCCTTCAGGCTTCAGGGGGACTGGTCCTCCTGGAGGAGATGCTCGCCTTGGGGAATAATCA
CTTTATTGGTTTTGTGAATGATTCTGTGACTAAGTCTATTGTGGCTTTGCGCTTAACTCTGGTGGTGAAGGTCAGCACCTGTGTGCCGGG
GGAGAGTCACGCAAATGACTTGGAGTGTTCAGGAAAAGGAAAATGCACCACGAAGCCGTCAGAGGCAACTTTTTCCTGTACCTGTGAGGA
GCAGTACGTGGGTACTTTCTGTGAAGAATACGATGCTTGCCAGAGGAAACCTTGCCAAAACAACGCGAGCTGTATTGATGCAAATGAAAA
GCAAGATGGGAGCAATTTCACCTGTGTTTGCCTTCCTGGTTATACTGGAGAGCTTTGCCAGTCCAAGATTGATTACTGCATCCTAGACCC
ATGCAGAAATGGAGCAACATGCATTTCCAGTCTCAGTGGATTCACCTGCCAGTGTCCAGAAGGATACTTCGGATCTGCTTGTGAAGAAAA
GGTGGACCCCTGCGCCTCGTCTCCGTGCCAGAACAACGGCACCTGCTATGTGGACGGGGTACACTTTACCTGCAACTGCAGCCCGGGCTT
CACAGGGCCGACCTGTGCCCAGCTTATTGACTTCTGTGCCCTCAGCCCCTGTGCTCATGGCACGTGCCGCAGCGTGGGCACCAGCTACAA
ATGCCTCTGTGATCCAGGTTACCATGGCCTCTACTGTGAGGAGGAATATAATGAGTGCCTCTCCGCTCCATGCCTGAATGCAGCCACCTG
CAGGGACCTCGTTAATGGCTATGAGTGTGTGTGCCTGGCAGAATACAAAGGAACACACTGTGAATTGTACAAGGATCCCTGCGCTAACGT
CAGCTGTCTGAACGGAGCCACCTGTGACAGCGACGGCCTGAATGGCACGTGCATCTGTGCACCCGGGTTTACAGGTGAAGAGTGCGACAT
TGACATAAATGAATGTGACAGTAACCCCTGCCACCATGGTGGGAGCTGCCTGGACCAGCCCAATGGTTATAACTGCCACTGCCCGCATGG
TTGGGTGGGAGCAAACTGTGAGATCCACCTCCAATGGAAGTCCGGGCACATGGCGGAGAGCCTCACCAACATGCCACGGCACTCCCTCTA
CATCATCATTGGAGCCCTCTGCGTGGCCTTCATCCTTATGCTGATCATCCTGATCGTGGGGATTTGCCGCATCAGCCGCATTGAATACCA
GGGTTCTTCCAGGCCAGCCTATGAGGAGTTCTACAACTGCCGCAGCATCGACAGCGAGTTCAGCAATGCCATTGCATCCATCCGGCATGC
CAGGTTTGGAAAGAAATCCCGGCCTGCAATGTATGATGTGAGCCCCATCGCCTATGAAGATTACAGTCCTGATGACAAACCCTTGGTCAC
ACTGATTAAAACTAAAGATTTGTAATCTTTTTTTGGATTATTTTTCAAAAAGATGAGATACTACACTCATTTAAATATTTTTAAGAAAAT
AAAAAGCTTAAGAAATTTAAAATGCTAGCTGCTCAAGAGTTTTCAGTAGAATATTTAAGAACTAATTTTCTGCAGCTTTTAGTTTGGAAA
AAATATTTTAAAAACAAAATTTGTGAAACCTATAGACGATGTTTTAATGTACCTTCAGCTCTCTAAACTGTGTGCTTCTACTAGTGTGTG
CTCTTTTCACTGTAGACACTATCACGAGACCCAGATTAATTTCTGTGGTTGTTACAGAATAAGTCTAATCAAGGAGAAGTTTCTGTTTGA
CGTTTGAGTGCCGGCTTTCTGAGTAGAGTTAGGAAAACCACGTAACGTAGCATATGATGTATAATAGAGTATACCCGTTACTTAAAAAGA
AGTCTGAAATGTTCGTTTTGTGGAAAAGAAACTAGTTAAATTTACTATTCCTAACCCGAATGAAATTAGCCTTTGCCTTATTCTGTGCAT
GGGTAAGTAACTTATTTCTGCACTGTTTTGTTGAACTTTGTGGAAACATTCTTTCGAGTTTGTTTTTGTCATTTTCGTAACAGTCGTCGA
ACTAGGCCTCAAAAACATACGTAACGAAAAGGCCTAGCGAGGCAAATTCTGATTGATTTGAATCTATATTTTTCTTTAAAAAGTCAAGGG
TTCTATATTGTGAGTAAATTAAATTTACATTTGAGTTGTTTGTTGCTAAGAGGTAGTAAATGTAAGAGAGTACTGGTTCCTTCAGTAGTG
AGTATTTCTCATAGTGCAGCTTTATTTATCTCCAGGATGTTTTTGTGGCTGTATTTGATTGATATGTGCTTCTTCTGATTCTTGCTAATT

>94239_94239_3_TRIP12-DNER_TRIP12_chr2_230642030_ENST00000389045_DNER_chr2_230456604_ENST00000341772_length(amino acids)=2143AA_BP=0
MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGSRRGSGLGKRGAAEARRQEKMADPESNQEAVNSSAARTDEAPQGAAASSSVAGAVGMT
TSGESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQASDESQQLQAVIEMCQLLVMGNEETLGGFP
VKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVDAIPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCL
LYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLV
VTPPILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCGASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVD
TMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIEAAHQVGEDEISLSTLGRVYTIDFNSMQQINEDTGTARAIQRKPNPLANSNTSG
YSESKKDDARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIASMLSSQDLKIVV
GALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAESESLLTSPPKACTNGSGSMGSTTSVSSGTATAATHAAADLGSPSLQHSRDDSLDL
SPQGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKSPTTTQSPKSSFLASLNPKTWGRLSTQSNSNNIEPARTAGGSGLARAASKD
TISNNREKIKGWIKEQAHKFVERYFSSENMDGSNPALNVLQRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLY
LTSKSEKDAVSREIRLKRFLHVFFSSPLPGEEPIGRVEPVGNAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGTGGSFSLNRGSQALKF
FNTHQLKCQLQRHPDCANVKQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGE
HLLPYNMTVYQAVRQFSIQAEDERESTDDESNPLGRAGIWTKTHTIWYKPVREDEESNKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHD
GVCPSVSNPLEVYLIPTPPENITFEDPSLDVILLLRVLHAISRYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTW
LTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNPEINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQY
ENEVGTGLGPTLEFYALVSQELQRADLGLWRGEEVTLSNPKGSQEGTKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMD
FRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQLVADPCASNPCHHGNCSSSSSSSSDGYLCICN
EGYEGPNCEQALPSLPATGWTESMAPRQLQPVPATQEPDKILPRSQATVTLPTWQPKTGQKVVEMKWDQVEVIPDIACGNASSNSSAGGR
LVSFEVPQNTSVKIRQDATASLILLWKVTATGFQQCSLIDGRSVTPLQASGGLVLLEEMLALGNNHFIGFVNDSVTKSIVALRLTLVVKV
STCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID
YCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRS
VGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFT
GEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSGHMAESLTNMPRHSLYIIIGALCVAFILMLIILIVGICRI

--------------------------------------------------------------
>94239_94239_4_TRIP12-DNER_TRIP12_chr2_230642031_ENST00000283943_DNER_chr2_230456604_ENST00000341772_length(transcript)=8332nt_BP=5483nt
GCTGCGGCTCAGCTGATAATTGAAGGAACCCGGAGCCGCCGCCGCCGCGCCGCTGGGGGGGGTGGGGGGAGCTAGTGGAAGTTACTGCCG
CGCCACCGAGTCCGGACCGGAGACTTTGGGGCCTAACTAGTGAATGGTAGTGTCTAGAAAGGGTATGTCCCTTCAAGAGAGAGGTGCCAA
TGTCCAACCGGCCTAATAACAATCCAGGGGGGTCACTGCGACGTTCACAGAGGAACACTGCCGGGGCCCAACCACAAGACGACTCAATAG
GAGGAAGAAGCTGCAGTTCATCATCTGCTGTGATAGTTCCACAACCAGAGGATCCAGACAGAGCCAATACTTCAGAAAGACAAAAAACGG
GGCAGGTGCCTAAGAAAGACAATTCTCGAGGAGTGAAGCGCAGTGCTAGTCCAGACTACAACAGGACCAATTCTCCTAGCTCTGCAAAAA
AACCAAAAGCACTTCAGCATACTGAATCTCCCTCAGAAACAAATAAGCCACATAGTAAGTCAAAGAAGAGACATTTAGACCAGGAGCAAC
AACTGAAATCTGCACAATCACCATCAACAAGCAAGGCTCATACCAGGAAGAGTGGGGCCACTGGCGGTTCACGGAGTCAGAAAAGAAAAA
GGACAGAGAGTTCTTGTGTAAAGAGTGGCTCCGGGTCTGAATCAACTGGTGCAGAAGAGAGATCTGCGAAACCTACCAAGCTGGCTTCAA
AATCAGCCACCTCAGCCAAAGCTGGGTGTAGCACCATCACTGATTCTTCTTCTGCTGCCTCTACTTCCTCCTCGTCTTCTGCTGTAGCCT
CGGCCTCCTCCACTGTACCACCAGGTGCCAGAGTGAAACAAGGAAAAGATCAGAACAAGGCCAGGCGTTCCCGTTCAGCGTCCAGTCCCA
GCCCCAGAAGAAGTAGCAGGGAAAAGGAACAGAGTAAAACTGGTGGCTCTTCAAAATTTGATTGGGCTGCTCGTTTCAGCCCTAAAGTTA
GCCTTCCTAAAACAAAACTGTCTCTTCCAGGGTCTTCTAAGTCAGAGACATCAAAACCTGGACCTTCTGGATTACAGGCCAAATTAGCAA
GTTTAAGAAAATCTACGAAGAAACGCAGTGAGTCTCCACCTGCTGAGCTCCCCAGTTTGAGGCGGAGCACACGCCAAAAGACCACGGGCT
CCTGTGCTAGTACCAGTCGGCGAGGCTCTGGCCTGGGCAAAAGAGGAGCAGCTGAAGCTCGTCGACAGGAGAAAATGGCAGACCCTGAAA
GCAACCAGGAGGCAGTAAATTCTTCAGCTGCTCGGACAGATGAAGCTCCCCAAGGAGCTGCAGGGGCTGTTGGCATGACCACCTCTGGGG
AGAGTGAATCAGATGATTCCGAGATGGGACGTTTGCAAGCTTTGTTAGAGGCAAGGGGTCTTCCCCCTCACCTATTTGGTCCTCTTGGTC
CTCGGATGTCACAGCTTTTCCATAGAACAATTGGAAGTGGAGCTAGTTCTAAGGCCCAGCAGCTACTACAAGGATTGCAAGCCAGTGATG
AAAGTCAACAGCTTCAGGCAGTTATTGAGATGTGTCAGTTACTGGTCATGGGAAATGAGGAGACACTGGGAGGGTTTCCTGTCAAGAGTG
TTGTTCCAGCTTTGATTACGTTACTTCAGATGGAGCACAATTTTGATATTATGAACCATGCTTGTCGAGCCTTAACATACATGATGGAAG
CACTTCCTCGATCTTCTGCTGTTGTAGTAGATGCTATTCCTGTCTTTTTAGAAAAGCTGCAAGTTATTCAGTGTATTGATGTGGCAGAGC
AGGCCTTGACTGCCTTGGAGATGTTGTCACGGAGACATAGTAAAGCCATTCTACAGGCGGGTGGTTTGGCAGACTGCTTGCTGTACCTAG
AATTCTTCAGCATAAATGCCCAAAGAAATGCATTAGCAATTGCAGCTAATTGCTGCCAGAGTATCACGCCAGATGAATTTCATTTTGTGG
CAGATTCACTCCCATTGCTAACCCAAAGGCTAACACATCAGGATAAAAAGTCAGTAGAAAGCACTTGCCTTTGTTTTGCACGCCTAGTGG
ACAACTTCCAGCATGAGGAGAATTTACTCCAGCAGGTTGCTTCCAAAGATCTGCTTACAAATGTTCAACAGCTGTTGGTAGTGACTCCAC
CCATTTTAAGTTCTGGGATGTTTATAATGGTGGTTCGCATGTTTTCTCTGATGTGTTCCAACTGTCCAACTTTAGCTGTTCAACTTATGA
AACAAAACATTGCAGAAACGCTTCACTTTCTCCTGTGTGGTGCCTCCAATGGAAGTTGTCAGGAACAGATTGATCTTGTTCCACGAAGCC
CTCAAGAGTTGTATGAACTGACATCTCTGATTTGTGAACTTATGCCATGTTTACCAAAAGAAGGCATTTTTGCAGTTGATACCATGTTGA
AGAAGGGAAATGCACAGAACACAGATGGTGCGATATGGCAGTGGCGTGATGATCGGGGCCTCTGGCATCCATATAACAGGATTGACAGCC
GGATCATTGAGCAAATCAATGAGGACACGGGAACAGCACGTGCCATTCAGAGAAAACCTAACCCGTTAGCCAATAGTAACACTAGTGGAT
ATTCAGAGTCAAAGAAGGATGATGCTCGAGCACAGCTTATGAAAGAGGATCCGGAACTGGCTAAGTCTTTTATTAAGACATTATTTGGTG
TTCTTTATGAAGTGTATAGTTCCTCAGCAGGACCTGCGGTCAGACATAAGTGCCTTAGAGCAATTCTTAGGATAATTTATTTTGCGGATG
CTGAACTTCTGAAGGATGTTCTGAAAAATCATGCTGTTTCAAGTCACATTGCTTCCATGCTGTCAAGCCAAGACCTGAAGATAGTAGTGG
GAGCACTTCAGATGGCAGAAATTTTAATGCAGAAGTTACCTGATATTTTTAGTGTTTACTTCAGAAGAGAAGGTGTAATGCATCAAGTAA
AACACTTAGCAGAATCAGAGTCTTTGTTGACAAGTCCACCAAAGGCATGTACGAATGGATCGGGATCCATGGGATCCACAACTTCAGTCA
GCAGTGGGACAGCCACAGCTGCCACTCATGCTGCAGCTGACTTGGGATCACCCAGCTTGCAGCACAGCAGGGATGATTCTTTAGATCTCA
GCCCTCAAGGTCGATTAAGTGATGTTCTAAAGAGAAAACGACTGCCAAAACGAGGGCCAAGAAGGCCAAAGTACTCACCTCCAAGAGATG
ATGACAAAGTAGACAATCAAGCTAAAAGCCCCACCACTACTCAGTCACCTAAATCTTCTTTCCTGGCAAGCTTGAATCCAAAAACATGGG
GAAGGTTAAGTACACAGTCCAACAGCAACAACATTGAGCCAGCACGGACTGCGGGAGGTAGTGGCCTTGCCAGGGCTGCCTCAAAGGATA
CCATCTCCAATAATAGAGAAAAAATTAAAGGTTGGATTAAGGAGCAGGCACATAAATTTGTAGAACGTTATTTCAGTTCTGAGAATATGG
ATGGAAGCAACCCTGCATTGAATGTCCTTCAGAGACTTTGTGCTGCAACCGAACAACTCAACCTCCAGGTGGATGGTGGAGCTGAGTGCC
TTGTAGAAATCCGTAGCATAGTCTCAGAGTCAGATGTTTCATCATTTGAAATCCAACATAGTGGATTTGTGAAGCAGCTGTTGCTTTATT
TGACATCTAAAAGTGAAAAGGATGCTGTGAGCAGAGAGATCAGATTAAAGCGATTTCTTCATGTATTTTTTTCTTCTCCACTTCCTGGAG
AAGAGCCCATTGGAAGAGTGGAACCAGTGGGTAATGCACCTTTGTTGGCATTAGTTCACAAGATGAACAACTGCCTCAGCCAGATGGAAC
AATTTCCAGTCAAAGTACATGATTTCCCTAGTGGAAATGGGACAGGAGGCAGCTTTTCTCTCAACAGAGGATCACAGGCTTTAAAATTTT
TCAACACACATCAATTAAAATGCCAGTTACAAAGGCATCCAGACTGTGCAAATGTGAAGCAGTGGAAGGGTGGACCTGTCAAGATTGACC
CTCTGGCTTTGGTACAAGCCATCGAGAGATACCTTGTAGTTAGAGGGTATGGAAGAGTAAGAGAAGATGATGAAGACAGCGATGACGATG
GATCAGATGAGGAAATAGATGAGTCTCTGGCTGCTCAGTTCCTAAATTCAGGAAATGTAAGACACAGGCTGCAGTTTTATATTGGAGAAC
ATTTGCTGCCGTATAACATGACTGTGTATCAGGCAGTACGGCAGTTTAGTATACAGGCTGAAGATGAAAGAGAATCCACAGATGATGAGA
GCAATCCTCTAGGCAGAGCTGGTATTTGGACAAAGACTCATACAATATGGTATAAACCTGTGAGAGAGGATGAAGAAAGTAATAAAGATT
GTGTTGGTGGTAAAAGAGGAAGAGCCCAAACAGCTCCAACGAAAACTTCCCCTAGAAATGCAAAAAAGCATGATGAGTTATGGCACGATG
GAGTGTGCCCATCAGTATCAAATCCTTTAGAAGTTTACCTCATTCCCACACCACCTGAAAATATAACATTTGAAGACCCGTCATTAGATG
TGATCCTTCTTTTAAGAGTTTTACATGCTATCAGTCGATACTGGTATTACTTGTATGATAATGCAATGTGCAAGGAAATTATTCCAACTA
GTGAATTTATTAACAGTAAGTTAACAGCAAAAGCAAATAGGCAACTTCAAGATCCTTTAGTAATCATGACAGGAAACATCCCAACATGGC
TTACTGAGCTAGGAAAAACCTGCCCATTTTTCTTTCCTTTTGATACCCGGCAAATGCTTTTTTATGTAACTGCATTTGATCGGGACCGAG
CAATGCAAAGATTACTTGATACCAACCCAGAAATCAACCAGTCTGATTCTCAAGATAGCAGAGTTGCACCTAGATTGGATAGAAAAAAAC
GTACTGTGAACCGAGAGGAGCTGCTGAAACAGGCGGAGTCTGTGATGCAGGACCTCGGCAGCTCACGGGCCATGTTAGAAATCCAGTATG
AAAATGAGGTTGGTACAGGTCTTGGGCCTACACTGGAGTTTTATGCGCTTGTATCTCAGGAACTACAGAGAGCTGACTTGGGTCTTTGGA
GAGGTGAAGAAGTAACTCTTAGCAATCCAAAAGGGAGCCAAGAAGGGACCAAGTATATTCAAAACCTCCAGGGCCTGTTTGCGCTTCCCT
TTGGTAGGACAGCAAAGCCAGCTCATATCGCAAAGGTTAAGATGAAGTTTCGCTTCTTAGGAAAATTAATGGCCAAGGCTATCATGGATT
TCAGATTGGTGGACCTTCCCCTTGGCTTACCCTTTTATAAATGGATGCTACGGCAAGAAACTTCACTGACATCACACGATTTGTTTGACA
TCGACCCAGTTGTAGCCAGATCAGTTTATCACCTAGAAGACATTGTCAGACAGAAGAAAAGACTTGAACAAGATAAATCCCAGCTTGTTG
CAGATCCTTGTGCCAGCAACCCTTGTCACCATGGCAACTGCAGCAGCAGCAGCAGCAGCAGCAGCGATGGCTACCTCTGCATTTGCAATG
AAGGCTATGAAGGTCCCAACTGTGAACAGGCACTTCCCAGTCTCCCAGCCACTGGCTGGACCGAATCCATGGCACCCCGACAGCTTCAGC
CTGTTCCTGCTACTCAGGAGCCTGACAAAATCCTGCCTCGCTCTCAGGCAACGGTGACACTGCCTACCTGGCAGCCGAAAACAGGGCAGA
AAGTTGTAGAAATGAAATGGGATCAAGTGGAGGTGATCCCAGATATTGCCTGTGGGAATGCCAGTTCTAACAGCTCTGCGGGTGGCCGCC
TGGTATCCTTTGAAGTGCCACAGAACACCTCAGTCAAGATTCGGCAAGATGCCACTGCCTCACTGATTTTGCTCTGGAAGGTCACGGCCA
CAGGATTCCAACAGTGCTCCCTCATAGATGGACGAAGTGTGACCCCCCTTCAGGCTTCAGGGGGACTGGTCCTCCTGGAGGAGATGCTCG
CCTTGGGGAATAATCACTTTATTGGTTTTGTGAATGATTCTGTGACTAAGTCTATTGTGGCTTTGCGCTTAACTCTGGTGGTGAAGGTCA
GCACCTGTGTGCCGGGGGAGAGTCACGCAAATGACTTGGAGTGTTCAGGAAAAGGAAAATGCACCACGAAGCCGTCAGAGGCAACTTTTT
CCTGTACCTGTGAGGAGCAGTACGTGGGTACTTTCTGTGAAGAATACGATGCTTGCCAGAGGAAACCTTGCCAAAACAACGCGAGCTGTA
TTGATGCAAATGAAAAGCAAGATGGGAGCAATTTCACCTGTGTTTGCCTTCCTGGTTATACTGGAGAGCTTTGCCAGTCCAAGATTGATT
ACTGCATCCTAGACCCATGCAGAAATGGAGCAACATGCATTTCCAGTCTCAGTGGATTCACCTGCCAGTGTCCAGAAGGATACTTCGGAT
CTGCTTGTGAAGAAAAGGTGGACCCCTGCGCCTCGTCTCCGTGCCAGAACAACGGCACCTGCTATGTGGACGGGGTACACTTTACCTGCA
ACTGCAGCCCGGGCTTCACAGGGCCGACCTGTGCCCAGCTTATTGACTTCTGTGCCCTCAGCCCCTGTGCTCATGGCACGTGCCGCAGCG
TGGGCACCAGCTACAAATGCCTCTGTGATCCAGGTTACCATGGCCTCTACTGTGAGGAGGAATATAATGAGTGCCTCTCCGCTCCATGCC
TGAATGCAGCCACCTGCAGGGACCTCGTTAATGGCTATGAGTGTGTGTGCCTGGCAGAATACAAAGGAACACACTGTGAATTGTACAAGG
ATCCCTGCGCTAACGTCAGCTGTCTGAACGGAGCCACCTGTGACAGCGACGGCCTGAATGGCACGTGCATCTGTGCACCCGGGTTTACAG
GTGAAGAGTGCGACATTGACATAAATGAATGTGACAGTAACCCCTGCCACCATGGTGGGAGCTGCCTGGACCAGCCCAATGGTTATAACT
GCCACTGCCCGCATGGTTGGGTGGGAGCAAACTGTGAGATCCACCTCCAATGGAAGTCCGGGCACATGGCGGAGAGCCTCACCAACATGC
CACGGCACTCCCTCTACATCATCATTGGAGCCCTCTGCGTGGCCTTCATCCTTATGCTGATCATCCTGATCGTGGGGATTTGCCGCATCA
GCCGCATTGAATACCAGGGTTCTTCCAGGCCAGCCTATGAGGAGTTCTACAACTGCCGCAGCATCGACAGCGAGTTCAGCAATGCCATTG
CATCCATCCGGCATGCCAGGTTTGGAAAGAAATCCCGGCCTGCAATGTATGATGTGAGCCCCATCGCCTATGAAGATTACAGTCCTGATG
ACAAACCCTTGGTCACACTGATTAAAACTAAAGATTTGTAATCTTTTTTTGGATTATTTTTCAAAAAGATGAGATACTACACTCATTTAA
ATATTTTTAAGAAAATAAAAAGCTTAAGAAATTTAAAATGCTAGCTGCTCAAGAGTTTTCAGTAGAATATTTAAGAACTAATTTTCTGCA
GCTTTTAGTTTGGAAAAAATATTTTAAAAACAAAATTTGTGAAACCTATAGACGATGTTTTAATGTACCTTCAGCTCTCTAAACTGTGTG
CTTCTACTAGTGTGTGCTCTTTTCACTGTAGACACTATCACGAGACCCAGATTAATTTCTGTGGTTGTTACAGAATAAGTCTAATCAAGG
AGAAGTTTCTGTTTGACGTTTGAGTGCCGGCTTTCTGAGTAGAGTTAGGAAAACCACGTAACGTAGCATATGATGTATAATAGAGTATAC
CCGTTACTTAAAAAGAAGTCTGAAATGTTCGTTTTGTGGAAAAGAAACTAGTTAAATTTACTATTCCTAACCCGAATGAAATTAGCCTTT
GCCTTATTCTGTGCATGGGTAAGTAACTTATTTCTGCACTGTTTTGTTGAACTTTGTGGAAACATTCTTTCGAGTTTGTTTTTGTCATTT
TCGTAACAGTCGTCGAACTAGGCCTCAAAAACATACGTAACGAAAAGGCCTAGCGAGGCAAATTCTGATTGATTTGAATCTATATTTTTC
TTTAAAAAGTCAAGGGTTCTATATTGTGAGTAAATTAAATTTACATTTGAGTTGTTTGTTGCTAAGAGGTAGTAAATGTAAGAGAGTACT
GGTTCCTTCAGTAGTGAGTATTTCTCATAGTGCAGCTTTATTTATCTCCAGGATGTTTTTGTGGCTGTATTTGATTGATATGTGCTTCTT

>94239_94239_4_TRIP12-DNER_TRIP12_chr2_230642031_ENST00000283943_DNER_chr2_230456604_ENST00000341772_length(amino acids)=2413AA_BP=0
MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGRSCSSSSAVIVPQPEDPDRANTSERQKTGQVPKKDNSRGVKRSASPDYNRTNSPSSAK
KPKALQHTESPSETNKPHSKSKKRHLDQEQQLKSAQSPSTSKAHTRKSGATGGSRSQKRKRTESSCVKSGSGSESTGAEERSAKPTKLAS
KSATSAKAGCSTITDSSSAASTSSSSSAVASASSTVPPGARVKQGKDQNKARRSRSASSPSPRRSSREKEQSKTGGSSKFDWAARFSPKV
SLPKTKLSLPGSSKSETSKPGPSGLQAKLASLRKSTKKRSESPPAELPSLRRSTRQKTTGSCASTSRRGSGLGKRGAAEARRQEKMADPE
SNQEAVNSSAARTDEAPQGAAGAVGMTTSGESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQASD
ESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVDAIPVFLEKLQVIQCIDVAE
QALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLV
DNFQHEENLLQQVASKDLLTNVQQLLVVTPPILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCGASNGSCQEQIDLVPRS
PQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIEQINEDTGTARAIQRKPNPLANSNTSG
YSESKKDDARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIASMLSSQDLKIVV
GALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAESESLLTSPPKACTNGSGSMGSTTSVSSGTATAATHAAADLGSPSLQHSRDDSLDL
SPQGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKSPTTTQSPKSSFLASLNPKTWGRLSTQSNSNNIEPARTAGGSGLARAASKD
TISNNREKIKGWIKEQAHKFVERYFSSENMDGSNPALNVLQRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLY
LTSKSEKDAVSREIRLKRFLHVFFSSPLPGEEPIGRVEPVGNAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGTGGSFSLNRGSQALKF
FNTHQLKCQLQRHPDCANVKQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGE
HLLPYNMTVYQAVRQFSIQAEDERESTDDESNPLGRAGIWTKTHTIWYKPVREDEESNKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHD
GVCPSVSNPLEVYLIPTPPENITFEDPSLDVILLLRVLHAISRYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTW
LTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNPEINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQY
ENEVGTGLGPTLEFYALVSQELQRADLGLWRGEEVTLSNPKGSQEGTKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMD
FRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQLVADPCASNPCHHGNCSSSSSSSSDGYLCICN
EGYEGPNCEQALPSLPATGWTESMAPRQLQPVPATQEPDKILPRSQATVTLPTWQPKTGQKVVEMKWDQVEVIPDIACGNASSNSSAGGR
LVSFEVPQNTSVKIRQDATASLILLWKVTATGFQQCSLIDGRSVTPLQASGGLVLLEEMLALGNNHFIGFVNDSVTKSIVALRLTLVVKV
STCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID
YCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRS
VGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFT
GEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSGHMAESLTNMPRHSLYIIIGALCVAFILMLIILIVGICRI

--------------------------------------------------------------
>94239_94239_5_TRIP12-DNER_TRIP12_chr2_230642031_ENST00000389044_DNER_chr2_230456604_ENST00000341772_length(transcript)=8466nt_BP=5617nt
AGCTGATAATTGAAGGAACCCGGAGCCGCCGCCGCCGCGCCGCTGGGGGGGGTGGGGGGAGCTAGTGGAAGTTACTGCCGCGCCACCGAG
TCCGGACCGGAGACTTTGGGGCCTAACTAGTGAATGGTAGTGTCTAGAAAGGGTATGTCCCTTCAAGAGAGAGGTGCCAATGTCCAACCG
GCCTAATAACAATCCAGGGGGGTCACTGCGACGTTCACAGAGGAACACTGCCGGGGCCCAACCACAAGACGACTCAATAGGAGGAAGGTC
ACATTTAGGGCAGGCAAAACATAAGGGATATAGCCCTCCTGAGAGTAGAAAATCTAATTCTAAGGCACCCAAAGTGCAGTCTAATACTAC
TTCTGAACTGTCAAGGGGACACCTTTCTAAAAGAAGCTGCAGTTCATCATCTGCTGTGATAGTTCCACAACCAGAGGATCCAGACAGAGC
CAATACTTCAGAAAGACAAAAAACGGGGCAGGTGCCTAAGAAAGACAATTCTCGAGGAGTGAAGCGCAGTGCTAGTCCAGACTACAACAG
GACCAATTCTCCTAGCTCTGCAAAAAAACCAAAAGCACTTCAGCATACTGAATCTCCCTCAGAAACAAATAAGCCACATAGTAAGTCAAA
GAAGAGACATTTAGACCAGGAGCAACAACTGAAATCTGCACAATCACCATCAACAAGCAAGGCTCATACCAGGAAGAGTGGGGCCACTGG
CGGTTCACGGAGTCAGAAAAGAAAAAGGACAGAGAGTTCTTGTGTAAAGAGTGGCTCCGGGTCTGAATCAACTGGTGCAGAAGAGAGATC
TGCGAAACCTACCAAGCTGGCTTCAAAATCAGCCACCTCAGCCAAAGCTGGGTGTAGCACCATCACTGATTCTTCTTCTGCTGCCTCTAC
TTCCTCCTCGTCTTCTGCTGTAGCCTCGGCCTCCTCCACTGTACCACCAGGTGCCAGAGTGAAACAAGGAAAAGATCAGAACAAGGCCAG
GCGTTCCCGTTCAGCGTCCAGTCCCAGCCCCAGAAGAAGTAGCAGGGAAAAGGAACAGAGTAAAACTGGTGGCTCTTCAAAATTTGATTG
GGCTGCTCGTTTCAGCCCTAAAGTTAGCCTTCCTAAAACAAAACTGTCTCTTCCAGGGTCTTCTAAGTCAGAGACATCAAAACCTGGACC
TTCTGGATTACAGGCCAAATTAGCAAGTTTAAGAAAATCTACGAAGAAACGCAGTGAGTCTCCACCTGCTGAGCTCCCCAGTTTGAGGCG
GAGCACACGCCAAAAGACCACGGGCTCCTGTGCTAGTACCAGTCGGCGAGGCTCTGGCCTGGGCAAAAGAGGAGCAGCTGAAGCTCGTCG
ACAGGAGAAAATGGCAGACCCTGAAAGCAACCAGGAGGCAGTAAATTCTTCAGCTGCTCGGACAGATGAAGCTCCCCAAGGAGCTGCAGC
CTCTAGTTCTGTTGCAGGGGCTGTTGGCATGACCACCTCTGGGGAGAGTGAATCAGATGATTCCGAGATGGGACGTTTGCAAGCTTTGTT
AGAGGCAAGGGGTCTTCCCCCTCACCTATTTGGTCCTCTTGGTCCTCGGATGTCACAGCTTTTCCATAGAACAATTGGAAGTGGAGCTAG
TTCTAAGGCCCAGCAGCTACTACAAGGATTGCAAGCCAGTGATGAAAGTCAACAGCTTCAGGCAGTTATTGAGATGTGTCAGTTACTGGT
CATGGGAAATGAGGAGACACTGGGAGGGTTTCCTGTCAAGAGTGTTGTTCCAGCTTTGATTACGTTACTTCAGATGGAGCACAATTTTGA
TATTATGAACCATGCTTGTCGAGCCTTAACATACATGATGGAAGCACTTCCTCGATCTTCTGCTGTTGTAGTAGATGCTATTCCTGTCTT
TTTAGAAAAGCTGCAAGTTATTCAGTGTATTGATGTGGCAGAGCAGGCCTTGACTGCCTTGGAGATGTTGTCACGGAGACATAGTAAAGC
CATTCTACAGGCGGGTGGTTTGGCAGACTGCTTGCTGTACCTAGAATTCTTCAGCATAAATGCCCAAAGAAATGCATTAGCAATTGCAGC
TAATTGCTGCCAGAGTATCACGCCAGATGAATTTCATTTTGTGGCAGATTCACTCCCATTGCTAACCCAAAGGCTAACACATCAGGATAA
AAAGTCAGTAGAAAGCACTTGCCTTTGTTTTGCACGCCTAGTGGACAACTTCCAGCATGAGGAGAATTTACTCCAGCAGGTTGCTTCCAA
AGATCTGCTTACAAATGTTCAACAGCTGTTGGTAGTGACTCCACCCATTTTAAGTTCTGGGATGTTTATAATGGTGGTTCGCATGTTTTC
TCTGATGTGTTCCAACTGTCCAACTTTAGCTGTTCAACTTATGAAACAAAACATTGCAGAAACGCTTCACTTTCTCCTGTGTGGTGCCTC
CAATGGAAGTTGTCAGGAACAGATTGATCTTGTTCCACGAAGCCCTCAAGAGTTGTATGAACTGACATCTCTGATTTGTGAACTTATGCC
ATGTTTACCAAAAGAAGGCATTTTTGCAGTTGATACCATGTTGAAGAAGGGAAATGCACAGAACACAGATGGTGCGATATGGCAGTGGCG
TGATGATCGGGGCCTCTGGCATCCATATAACAGGATTGACAGCCGGATCATTGAGCAAATCAATGAGGACACGGGAACAGCACGTGCCAT
TCAGAGAAAACCTAACCCGTTAGCCAATAGTAACACTAGTGGATATTCAGAGTCAAAGAAGGATGATGCTCGAGCACAGCTTATGAAAGA
GGATCCGGAACTGGCTAAGTCTTTTATTAAGACATTATTTGGTGTTCTTTATGAAGTGTATAGTTCCTCAGCAGGACCTGCGGTCAGACA
TAAGTGCCTTAGAGCAATTCTTAGGATAATTTATTTTGCGGATGCTGAACTTCTGAAGGATGTTCTGAAAAATCATGCTGTTTCAAGTCA
CATTGCTTCCATGCTGTCAAGCCAAGACCTGAAGATAGTAGTGGGAGCACTTCAGATGGCAGAAATTTTAATGCAGAAGTTACCTGATAT
TTTTAGTGTTTACTTCAGAAGAGAAGGTGTAATGCATCAAGTAAAACACTTAGCAGAATCAGAGTCTTTGTTGACAAGTCCACCAAAGGC
ATGTACGAATGGATCGGGATCCATGGGATCCACAACTTCAGTCAGCAGTGGGACAGCCACAGCTGCCACTCATGCTGCAGCTGACTTGGG
ATCACCCAGCTTGCAGCACAGCAGGGATGATTCTTTAGATCTCAGCCCTCAAGGTCGATTAAGTGATGTTCTAAAGAGAAAACGACTGCC
AAAACGAGGGCCAAGAAGGCCAAAGTACTCACCTCCAAGAGATGATGACAAAGTAGACAATCAAGCTAAAAGCCCCACCACTACTCAGTC
ACCTAAATCTTCTTTCCTGGCAAGCTTGAATCCAAAAACATGGGGAAGGTTAAGTACACAGTCCAACAGCAACAACATTGAGCCAGCACG
GACTGCGGGAGGTAGTGGCCTTGCCAGGGCTGCCTCAAAGGATACCATCTCCAATAATAGAGAAAAAATTAAAGGTTGGATTAAGGAGCA
GGCACATAAATTTGTAGAACGTTATTTCAGTTCTGAGAATATGGATGGAAGCAACCCTGCATTGAATGTCCTTCAGAGACTTTGTGCTGC
AACCGAACAACTCAACCTCCAGGTGGATGGTGGAGCTGAGTGCCTTGTAGAAATCCGTAGCATAGTCTCAGAGTCAGATGTTTCATCATT
TGAAATCCAACATAGTGGATTTGTGAAGCAGCTGTTGCTTTATTTGACATCTAAAAGTGAAAAGGATGCTGTGAGCAGAGAGATCAGATT
AAAGCGATTTCTTCATGTATTTTTTTCTTCTCCACTTCCTGGAGAAGAGCCCATTGGAAGAGTGGAACCAGTGGGTAATGCACCTTTGTT
GGCATTAGTTCACAAGATGAACAACTGCCTCAGCCAGATGGAACAATTTCCAGTCAAAGTACATGATTTCCCTAGTGGAAATGGGACAGG
AGGCAGCTTTTCTCTCAACAGAGGATCACAGGCTTTAAAATTTTTCAACACACATCAATTAAAATGCCAGTTACAAAGGCATCCAGACTG
TGCAAATGTGAAGCAGTGGAAGGGTGGACCTGTCAAGATTGACCCTCTGGCTTTGGTACAAGCCATCGAGAGATACCTTGTAGTTAGAGG
GTATGGAAGAGTAAGAGAAGATGATGAAGACAGCGATGACGATGGATCAGATGAGGAAATAGATGAGTCTCTGGCTGCTCAGTTCCTAAA
TTCAGGAAATGTAAGACACAGGCTGCAGTTTTATATTGGAGAACATTTGCTGCCGTATAACATGACTGTGTATCAGGCAGTACGGCAGTT
TAGTATACAGGCTGAAGATGAAAGAGAATCCACAGATGATGAGAGCAATCCTCTAGGCAGAGCTGGTATTTGGACAAAGACTCATACAAT
ATGGTATAAACCTGTGAGAGAGGATGAAGAAAGTAATAAAGATTGTGTTGGTGGTAAAAGAGGAAGAGCCCAAACAGCTCCAACGAAAAC
TTCCCCTAGAAATGCAAAAAAGCATGATGAGTTATGGCACGATGGAGTGTGCCCATCAGTATCAAATCCTTTAGAAGTTTACCTCATTCC
CACACCACCTGAAAATATAACATTTGAAGACCCGTCATTAGATGTGATCCTTCTTTTAAGAGTTTTACATGCTATCAGTCGATACTGGTA
TTACTTGTATGATAATGCAATGTGCAAGGAAATTATTCCAACTAGTGAATTTATTAACAGTAAGTTAACAGCAAAAGCAAATAGGCAACT
TCAAGATCCTTTAGTAATCATGACAGGAAACATCCCAACATGGCTTACTGAGCTAGGAAAAACCTGCCCATTTTTCTTTCCTTTTGATAC
CCGGCAAATGCTTTTTTATGTAACTGCATTTGATCGGGACCGAGCAATGCAAAGATTACTTGATACCAACCCAGAAATCAACCAGTCTGA
TTCTCAAGATAGCAGAGTTGCACCTAGATTGGATAGAAAAAAACGTACTGTGAACCGAGAGGAGCTGCTGAAACAGGCGGAGTCTGTGAT
GCAGGACCTCGGCAGCTCACGGGCCATGTTAGAAATCCAGTATGAAAATGAGGTTGGTACAGGTCTTGGGCCTACACTGGAGTTTTATGC
GCTTGTATCTCAGGAACTACAGAGAGCTGACTTGGGTCTTTGGAGAGGTGAAGAAGTAACTCTTAGCAATCCAAAAGGGAGCCAAGAAGG
GACCAAGTATATTCAAAACCTCCAGGGCCTGTTTGCGCTTCCCTTTGGTAGGACAGCAAAGCCAGCTCATATCGCAAAGGTTAAGATGAA
GTTTCGCTTCTTAGGAAAATTAATGGCCAAGGCTATCATGGATTTCAGATTGGTGGACCTTCCCCTTGGCTTACCCTTTTATAAATGGAT
GCTACGGCAAGAAACTTCACTGACATCACACGATTTGTTTGACATCGACCCAGTTGTAGCCAGATCAGTTTATCACCTAGAAGACATTGT
CAGACAGAAGAAAAGACTTGAACAAGATAAATCCCAGCTTGTTGCAGATCCTTGTGCCAGCAACCCTTGTCACCATGGCAACTGCAGCAG
CAGCAGCAGCAGCAGCAGCGATGGCTACCTCTGCATTTGCAATGAAGGCTATGAAGGTCCCAACTGTGAACAGGCACTTCCCAGTCTCCC
AGCCACTGGCTGGACCGAATCCATGGCACCCCGACAGCTTCAGCCTGTTCCTGCTACTCAGGAGCCTGACAAAATCCTGCCTCGCTCTCA
GGCAACGGTGACACTGCCTACCTGGCAGCCGAAAACAGGGCAGAAAGTTGTAGAAATGAAATGGGATCAAGTGGAGGTGATCCCAGATAT
TGCCTGTGGGAATGCCAGTTCTAACAGCTCTGCGGGTGGCCGCCTGGTATCCTTTGAAGTGCCACAGAACACCTCAGTCAAGATTCGGCA
AGATGCCACTGCCTCACTGATTTTGCTCTGGAAGGTCACGGCCACAGGATTCCAACAGTGCTCCCTCATAGATGGACGAAGTGTGACCCC
CCTTCAGGCTTCAGGGGGACTGGTCCTCCTGGAGGAGATGCTCGCCTTGGGGAATAATCACTTTATTGGTTTTGTGAATGATTCTGTGAC
TAAGTCTATTGTGGCTTTGCGCTTAACTCTGGTGGTGAAGGTCAGCACCTGTGTGCCGGGGGAGAGTCACGCAAATGACTTGGAGTGTTC
AGGAAAAGGAAAATGCACCACGAAGCCGTCAGAGGCAACTTTTTCCTGTACCTGTGAGGAGCAGTACGTGGGTACTTTCTGTGAAGAATA
CGATGCTTGCCAGAGGAAACCTTGCCAAAACAACGCGAGCTGTATTGATGCAAATGAAAAGCAAGATGGGAGCAATTTCACCTGTGTTTG
CCTTCCTGGTTATACTGGAGAGCTTTGCCAGTCCAAGATTGATTACTGCATCCTAGACCCATGCAGAAATGGAGCAACATGCATTTCCAG
TCTCAGTGGATTCACCTGCCAGTGTCCAGAAGGATACTTCGGATCTGCTTGTGAAGAAAAGGTGGACCCCTGCGCCTCGTCTCCGTGCCA
GAACAACGGCACCTGCTATGTGGACGGGGTACACTTTACCTGCAACTGCAGCCCGGGCTTCACAGGGCCGACCTGTGCCCAGCTTATTGA
CTTCTGTGCCCTCAGCCCCTGTGCTCATGGCACGTGCCGCAGCGTGGGCACCAGCTACAAATGCCTCTGTGATCCAGGTTACCATGGCCT
CTACTGTGAGGAGGAATATAATGAGTGCCTCTCCGCTCCATGCCTGAATGCAGCCACCTGCAGGGACCTCGTTAATGGCTATGAGTGTGT
GTGCCTGGCAGAATACAAAGGAACACACTGTGAATTGTACAAGGATCCCTGCGCTAACGTCAGCTGTCTGAACGGAGCCACCTGTGACAG
CGACGGCCTGAATGGCACGTGCATCTGTGCACCCGGGTTTACAGGTGAAGAGTGCGACATTGACATAAATGAATGTGACAGTAACCCCTG
CCACCATGGTGGGAGCTGCCTGGACCAGCCCAATGGTTATAACTGCCACTGCCCGCATGGTTGGGTGGGAGCAAACTGTGAGATCCACCT
CCAATGGAAGTCCGGGCACATGGCGGAGAGCCTCACCAACATGCCACGGCACTCCCTCTACATCATCATTGGAGCCCTCTGCGTGGCCTT
CATCCTTATGCTGATCATCCTGATCGTGGGGATTTGCCGCATCAGCCGCATTGAATACCAGGGTTCTTCCAGGCCAGCCTATGAGGAGTT
CTACAACTGCCGCAGCATCGACAGCGAGTTCAGCAATGCCATTGCATCCATCCGGCATGCCAGGTTTGGAAAGAAATCCCGGCCTGCAAT
GTATGATGTGAGCCCCATCGCCTATGAAGATTACAGTCCTGATGACAAACCCTTGGTCACACTGATTAAAACTAAAGATTTGTAATCTTT
TTTTGGATTATTTTTCAAAAAGATGAGATACTACACTCATTTAAATATTTTTAAGAAAATAAAAAGCTTAAGAAATTTAAAATGCTAGCT
GCTCAAGAGTTTTCAGTAGAATATTTAAGAACTAATTTTCTGCAGCTTTTAGTTTGGAAAAAATATTTTAAAAACAAAATTTGTGAAACC
TATAGACGATGTTTTAATGTACCTTCAGCTCTCTAAACTGTGTGCTTCTACTAGTGTGTGCTCTTTTCACTGTAGACACTATCACGAGAC
CCAGATTAATTTCTGTGGTTGTTACAGAATAAGTCTAATCAAGGAGAAGTTTCTGTTTGACGTTTGAGTGCCGGCTTTCTGAGTAGAGTT
AGGAAAACCACGTAACGTAGCATATGATGTATAATAGAGTATACCCGTTACTTAAAAAGAAGTCTGAAATGTTCGTTTTGTGGAAAAGAA
ACTAGTTAAATTTACTATTCCTAACCCGAATGAAATTAGCCTTTGCCTTATTCTGTGCATGGGTAAGTAACTTATTTCTGCACTGTTTTG
TTGAACTTTGTGGAAACATTCTTTCGAGTTTGTTTTTGTCATTTTCGTAACAGTCGTCGAACTAGGCCTCAAAAACATACGTAACGAAAA
GGCCTAGCGAGGCAAATTCTGATTGATTTGAATCTATATTTTTCTTTAAAAAGTCAAGGGTTCTATATTGTGAGTAAATTAAATTTACAT
TTGAGTTGTTTGTTGCTAAGAGGTAGTAAATGTAAGAGAGTACTGGTTCCTTCAGTAGTGAGTATTTCTCATAGTGCAGCTTTATTTATC
TCCAGGATGTTTTTGTGGCTGTATTTGATTGATATGTGCTTCTTCTGATTCTTGCTAATTTCCAACCATATTGAATAAATGTGATCAAGT

>94239_94239_5_TRIP12-DNER_TRIP12_chr2_230642031_ENST00000389044_DNER_chr2_230456604_ENST00000341772_length(amino acids)=2461AA_BP=0
MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGRSHLGQAKHKGYSPPESRKSNSKAPKVQSNTTSELSRGHLSKRSCSSSSAVIVPQPED
PDRANTSERQKTGQVPKKDNSRGVKRSASPDYNRTNSPSSAKKPKALQHTESPSETNKPHSKSKKRHLDQEQQLKSAQSPSTSKAHTRKS
GATGGSRSQKRKRTESSCVKSGSGSESTGAEERSAKPTKLASKSATSAKAGCSTITDSSSAASTSSSSSAVASASSTVPPGARVKQGKDQ
NKARRSRSASSPSPRRSSREKEQSKTGGSSKFDWAARFSPKVSLPKTKLSLPGSSKSETSKPGPSGLQAKLASLRKSTKKRSESPPAELP
SLRRSTRQKTTGSCASTSRRGSGLGKRGAAEARRQEKMADPESNQEAVNSSAARTDEAPQGAAASSSVAGAVGMTTSGESESDDSEMGRL
QALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQASDESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQME
HNFDIMNHACRALTYMMEALPRSSAVVVDAIPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNAL
AIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLVVTPPILSSGMFIMVV
RMFSLMCSNCPTLAVQLMKQNIAETLHFLLCGASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAI
WQWRDDRGLWHPYNRIDSRIIEQINEDTGTARAIQRKPNPLANSNTSGYSESKKDDARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGP
AVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIASMLSSQDLKIVVGALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAESESLLTS
PPKACTNGSGSMGSTTSVSSGTATAATHAAADLGSPSLQHSRDDSLDLSPQGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKSPT
TTQSPKSSFLASLNPKTWGRLSTQSNSNNIEPARTAGGSGLARAASKDTISNNREKIKGWIKEQAHKFVERYFSSENMDGSNPALNVLQR
LCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKSEKDAVSREIRLKRFLHVFFSSPLPGEEPIGRVEPVGN
APLLALVHKMNNCLSQMEQFPVKVHDFPSGNGTGGSFSLNRGSQALKFFNTHQLKCQLQRHPDCANVKQWKGGPVKIDPLALVQAIERYL
VVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGEHLLPYNMTVYQAVRQFSIQAEDERESTDDESNPLGRAGIWTK
THTIWYKPVREDEESNKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHDGVCPSVSNPLEVYLIPTPPENITFEDPSLDVILLLRVLHAIS
RYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNPEI
NQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLGLWRGEEVTLSNPKG
SQEGTKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHL
EDIVRQKKRLEQDKSQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLPATGWTESMAPRQLQPVPATQEPDKIL
PRSQATVTLPTWQPKTGQKVVEMKWDQVEVIPDIACGNASSNSSAGGRLVSFEVPQNTSVKIRQDATASLILLWKVTATGFQQCSLIDGR
SVTPLQASGGLVLLEEMLALGNNHFIGFVNDSVTKSIVALRLTLVVKVSTCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTF
CEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCAS
SPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNG
YECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANC
EIHLQWKSGHMAESLTNMPRHSLYIIIGALCVAFILMLIILIVGICRISRIEYQGSSRPAYEEFYNCRSIDSEFSNAIASIRHARFGKKS

--------------------------------------------------------------
>94239_94239_6_TRIP12-DNER_TRIP12_chr2_230642031_ENST00000389045_DNER_chr2_230456604_ENST00000341772_length(transcript)=7416nt_BP=4567nt
CCGGAGACTTTGGGGCCTAACTAGTGAATGGTAGTGTCTAGAAAGGGTATGTCCCTTCAAGAGAGAGGTGCCAATGTCCAACCGGCCTAA
TAACAATCCAGGGGGGTCACTGCGACGTTCACAGAGGAACACTGCCGGGGCCCAACCACAAGACGACTCAATAGGAGGAAGTCGGCGAGG
CTCTGGCCTGGGCAAAAGAGGAGCAGCTGAAGCTCGTCGACAGGAGAAAATGGCAGACCCTGAAAGCAACCAGGAGGCAGTAAATTCTTC
AGCTGCTCGGACAGATGAAGCTCCCCAAGGAGCTGCAGCCTCTAGTTCTGTTGCAGGGGCTGTTGGCATGACCACCTCTGGGGAGAGTGA
ATCAGATGATTCCGAGATGGGACGTTTGCAAGCTTTGTTAGAGGCAAGGGGTCTTCCCCCTCACCTATTTGGTCCTCTTGGTCCTCGGAT
GTCACAGCTTTTCCATAGAACAATTGGAAGTGGAGCTAGTTCTAAGGCCCAGCAGCTACTACAAGGATTGCAAGCCAGTGATGAAAGTCA
ACAGCTTCAGGCAGTTATTGAGATGTGTCAGTTACTGGTCATGGGAAATGAGGAGACACTGGGAGGGTTTCCTGTCAAGAGTGTTGTTCC
AGCTTTGATTACGTTACTTCAGATGGAGCACAATTTTGATATTATGAACCATGCTTGTCGAGCCTTAACATACATGATGGAAGCACTTCC
TCGATCTTCTGCTGTTGTAGTAGATGCTATTCCTGTCTTTTTAGAAAAGCTGCAAGTTATTCAGTGTATTGATGTGGCAGAGCAGGCCTT
GACTGCCTTGGAGATGTTGTCACGGAGACATAGTAAAGCCATTCTACAGGCGGGTGGTTTGGCAGACTGCTTGCTGTACCTAGAATTCTT
CAGCATAAATGCCCAAAGAAATGCATTAGCAATTGCAGCTAATTGCTGCCAGAGTATCACGCCAGATGAATTTCATTTTGTGGCAGATTC
ACTCCCATTGCTAACCCAAAGGCTAACACATCAGGATAAAAAGTCAGTAGAAAGCACTTGCCTTTGTTTTGCACGCCTAGTGGACAACTT
CCAGCATGAGGAGAATTTACTCCAGCAGGTTGCTTCCAAAGATCTGCTTACAAATGTTCAACAGCTGTTGGTAGTGACTCCACCCATTTT
AAGTTCTGGGATGTTTATAATGGTGGTTCGCATGTTTTCTCTGATGTGTTCCAACTGTCCAACTTTAGCTGTTCAACTTATGAAACAAAA
CATTGCAGAAACGCTTCACTTTCTCCTGTGTGGTGCCTCCAATGGAAGTTGTCAGGAACAGATTGATCTTGTTCCACGAAGCCCTCAAGA
GTTGTATGAACTGACATCTCTGATTTGTGAACTTATGCCATGTTTACCAAAAGAAGGCATTTTTGCAGTTGATACCATGTTGAAGAAGGG
AAATGCACAGAACACAGATGGTGCGATATGGCAGTGGCGTGATGATCGGGGCCTCTGGCATCCATATAACAGGATTGACAGCCGGATCAT
TGAGGCAGCCCATCAGGTCGGTGAGGATGAGATAAGCTTGTCCACTCTGGGACGAGTTTATACTATTGATTTTAATTCTATGCAGCAAAT
CAATGAGGACACGGGAACAGCACGTGCCATTCAGAGAAAACCTAACCCGTTAGCCAATAGTAACACTAGTGGATATTCAGAGTCAAAGAA
GGATGATGCTCGAGCACAGCTTATGAAAGAGGATCCGGAACTGGCTAAGTCTTTTATTAAGACATTATTTGGTGTTCTTTATGAAGTGTA
TAGTTCCTCAGCAGGACCTGCGGTCAGACATAAGTGCCTTAGAGCAATTCTTAGGATAATTTATTTTGCGGATGCTGAACTTCTGAAGGA
TGTTCTGAAAAATCATGCTGTTTCAAGTCACATTGCTTCCATGCTGTCAAGCCAAGACCTGAAGATAGTAGTGGGAGCACTTCAGATGGC
AGAAATTTTAATGCAGAAGTTACCTGATATTTTTAGTGTTTACTTCAGAAGAGAAGGTGTAATGCATCAAGTAAAACACTTAGCAGAATC
AGAGTCTTTGTTGACAAGTCCACCAAAGGCATGTACGAATGGATCGGGATCCATGGGATCCACAACTTCAGTCAGCAGTGGGACAGCCAC
AGCTGCCACTCATGCTGCAGCTGACTTGGGATCACCCAGCTTGCAGCACAGCAGGGATGATTCTTTAGATCTCAGCCCTCAAGGTCGATT
AAGTGATGTTCTAAAGAGAAAACGACTGCCAAAACGAGGGCCAAGAAGGCCAAAGTACTCACCTCCAAGAGATGATGACAAAGTAGACAA
TCAAGCTAAAAGCCCCACCACTACTCAGTCACCTAAATCTTCTTTCCTGGCAAGCTTGAATCCAAAAACATGGGGAAGGTTAAGTACACA
GTCCAACAGCAACAACATTGAGCCAGCACGGACTGCGGGAGGTAGTGGCCTTGCCAGGGCTGCCTCAAAGGATACCATCTCCAATAATAG
AGAAAAAATTAAAGGTTGGATTAAGGAGCAGGCACATAAATTTGTAGAACGTTATTTCAGTTCTGAGAATATGGATGGAAGCAACCCTGC
ATTGAATGTCCTTCAGAGACTTTGTGCTGCAACCGAACAACTCAACCTCCAGGTGGATGGTGGAGCTGAGTGCCTTGTAGAAATCCGTAG
CATAGTCTCAGAGTCAGATGTTTCATCATTTGAAATCCAACATAGTGGATTTGTGAAGCAGCTGTTGCTTTATTTGACATCTAAAAGTGA
AAAGGATGCTGTGAGCAGAGAGATCAGATTAAAGCGATTTCTTCATGTATTTTTTTCTTCTCCACTTCCTGGAGAAGAGCCCATTGGAAG
AGTGGAACCAGTGGGTAATGCACCTTTGTTGGCATTAGTTCACAAGATGAACAACTGCCTCAGCCAGATGGAACAATTTCCAGTCAAAGT
ACATGATTTCCCTAGTGGAAATGGGACAGGAGGCAGCTTTTCTCTCAACAGAGGATCACAGGCTTTAAAATTTTTCAACACACATCAATT
AAAATGCCAGTTACAAAGGCATCCAGACTGTGCAAATGTGAAGCAGTGGAAGGGTGGACCTGTCAAGATTGACCCTCTGGCTTTGGTACA
AGCCATCGAGAGATACCTTGTAGTTAGAGGGTATGGAAGAGTAAGAGAAGATGATGAAGACAGCGATGACGATGGATCAGATGAGGAAAT
AGATGAGTCTCTGGCTGCTCAGTTCCTAAATTCAGGAAATGTAAGACACAGGCTGCAGTTTTATATTGGAGAACATTTGCTGCCGTATAA
CATGACTGTGTATCAGGCAGTACGGCAGTTTAGTATACAGGCTGAAGATGAAAGAGAATCCACAGATGATGAGAGCAATCCTCTAGGCAG
AGCTGGTATTTGGACAAAGACTCATACAATATGGTATAAACCTGTGAGAGAGGATGAAGAAAGTAATAAAGATTGTGTTGGTGGTAAAAG
AGGAAGAGCCCAAACAGCTCCAACGAAAACTTCCCCTAGAAATGCAAAAAAGCATGATGAGTTATGGCACGATGGAGTGTGCCCATCAGT
ATCAAATCCTTTAGAAGTTTACCTCATTCCCACACCACCTGAAAATATAACATTTGAAGACCCGTCATTAGATGTGATCCTTCTTTTAAG
AGTTTTACATGCTATCAGTCGATACTGGTATTACTTGTATGATAATGCAATGTGCAAGGAAATTATTCCAACTAGTGAATTTATTAACAG
TAAGTTAACAGCAAAAGCAAATAGGCAACTTCAAGATCCTTTAGTAATCATGACAGGAAACATCCCAACATGGCTTACTGAGCTAGGAAA
AACCTGCCCATTTTTCTTTCCTTTTGATACCCGGCAAATGCTTTTTTATGTAACTGCATTTGATCGGGACCGAGCAATGCAAAGATTACT
TGATACCAACCCAGAAATCAACCAGTCTGATTCTCAAGATAGCAGAGTTGCACCTAGATTGGATAGAAAAAAACGTACTGTGAACCGAGA
GGAGCTGCTGAAACAGGCGGAGTCTGTGATGCAGGACCTCGGCAGCTCACGGGCCATGTTAGAAATCCAGTATGAAAATGAGGTTGGTAC
AGGTCTTGGGCCTACACTGGAGTTTTATGCGCTTGTATCTCAGGAACTACAGAGAGCTGACTTGGGTCTTTGGAGAGGTGAAGAAGTAAC
TCTTAGCAATCCAAAAGGGAGCCAAGAAGGGACCAAGTATATTCAAAACCTCCAGGGCCTGTTTGCGCTTCCCTTTGGTAGGACAGCAAA
GCCAGCTCATATCGCAAAGGTTAAGATGAAGTTTCGCTTCTTAGGAAAATTAATGGCCAAGGCTATCATGGATTTCAGATTGGTGGACCT
TCCCCTTGGCTTACCCTTTTATAAATGGATGCTACGGCAAGAAACTTCACTGACATCACACGATTTGTTTGACATCGACCCAGTTGTAGC
CAGATCAGTTTATCACCTAGAAGACATTGTCAGACAGAAGAAAAGACTTGAACAAGATAAATCCCAGCTTGTTGCAGATCCTTGTGCCAG
CAACCCTTGTCACCATGGCAACTGCAGCAGCAGCAGCAGCAGCAGCAGCGATGGCTACCTCTGCATTTGCAATGAAGGCTATGAAGGTCC
CAACTGTGAACAGGCACTTCCCAGTCTCCCAGCCACTGGCTGGACCGAATCCATGGCACCCCGACAGCTTCAGCCTGTTCCTGCTACTCA
GGAGCCTGACAAAATCCTGCCTCGCTCTCAGGCAACGGTGACACTGCCTACCTGGCAGCCGAAAACAGGGCAGAAAGTTGTAGAAATGAA
ATGGGATCAAGTGGAGGTGATCCCAGATATTGCCTGTGGGAATGCCAGTTCTAACAGCTCTGCGGGTGGCCGCCTGGTATCCTTTGAAGT
GCCACAGAACACCTCAGTCAAGATTCGGCAAGATGCCACTGCCTCACTGATTTTGCTCTGGAAGGTCACGGCCACAGGATTCCAACAGTG
CTCCCTCATAGATGGACGAAGTGTGACCCCCCTTCAGGCTTCAGGGGGACTGGTCCTCCTGGAGGAGATGCTCGCCTTGGGGAATAATCA
CTTTATTGGTTTTGTGAATGATTCTGTGACTAAGTCTATTGTGGCTTTGCGCTTAACTCTGGTGGTGAAGGTCAGCACCTGTGTGCCGGG
GGAGAGTCACGCAAATGACTTGGAGTGTTCAGGAAAAGGAAAATGCACCACGAAGCCGTCAGAGGCAACTTTTTCCTGTACCTGTGAGGA
GCAGTACGTGGGTACTTTCTGTGAAGAATACGATGCTTGCCAGAGGAAACCTTGCCAAAACAACGCGAGCTGTATTGATGCAAATGAAAA
GCAAGATGGGAGCAATTTCACCTGTGTTTGCCTTCCTGGTTATACTGGAGAGCTTTGCCAGTCCAAGATTGATTACTGCATCCTAGACCC
ATGCAGAAATGGAGCAACATGCATTTCCAGTCTCAGTGGATTCACCTGCCAGTGTCCAGAAGGATACTTCGGATCTGCTTGTGAAGAAAA
GGTGGACCCCTGCGCCTCGTCTCCGTGCCAGAACAACGGCACCTGCTATGTGGACGGGGTACACTTTACCTGCAACTGCAGCCCGGGCTT
CACAGGGCCGACCTGTGCCCAGCTTATTGACTTCTGTGCCCTCAGCCCCTGTGCTCATGGCACGTGCCGCAGCGTGGGCACCAGCTACAA
ATGCCTCTGTGATCCAGGTTACCATGGCCTCTACTGTGAGGAGGAATATAATGAGTGCCTCTCCGCTCCATGCCTGAATGCAGCCACCTG
CAGGGACCTCGTTAATGGCTATGAGTGTGTGTGCCTGGCAGAATACAAAGGAACACACTGTGAATTGTACAAGGATCCCTGCGCTAACGT
CAGCTGTCTGAACGGAGCCACCTGTGACAGCGACGGCCTGAATGGCACGTGCATCTGTGCACCCGGGTTTACAGGTGAAGAGTGCGACAT
TGACATAAATGAATGTGACAGTAACCCCTGCCACCATGGTGGGAGCTGCCTGGACCAGCCCAATGGTTATAACTGCCACTGCCCGCATGG
TTGGGTGGGAGCAAACTGTGAGATCCACCTCCAATGGAAGTCCGGGCACATGGCGGAGAGCCTCACCAACATGCCACGGCACTCCCTCTA
CATCATCATTGGAGCCCTCTGCGTGGCCTTCATCCTTATGCTGATCATCCTGATCGTGGGGATTTGCCGCATCAGCCGCATTGAATACCA
GGGTTCTTCCAGGCCAGCCTATGAGGAGTTCTACAACTGCCGCAGCATCGACAGCGAGTTCAGCAATGCCATTGCATCCATCCGGCATGC
CAGGTTTGGAAAGAAATCCCGGCCTGCAATGTATGATGTGAGCCCCATCGCCTATGAAGATTACAGTCCTGATGACAAACCCTTGGTCAC
ACTGATTAAAACTAAAGATTTGTAATCTTTTTTTGGATTATTTTTCAAAAAGATGAGATACTACACTCATTTAAATATTTTTAAGAAAAT
AAAAAGCTTAAGAAATTTAAAATGCTAGCTGCTCAAGAGTTTTCAGTAGAATATTTAAGAACTAATTTTCTGCAGCTTTTAGTTTGGAAA
AAATATTTTAAAAACAAAATTTGTGAAACCTATAGACGATGTTTTAATGTACCTTCAGCTCTCTAAACTGTGTGCTTCTACTAGTGTGTG
CTCTTTTCACTGTAGACACTATCACGAGACCCAGATTAATTTCTGTGGTTGTTACAGAATAAGTCTAATCAAGGAGAAGTTTCTGTTTGA
CGTTTGAGTGCCGGCTTTCTGAGTAGAGTTAGGAAAACCACGTAACGTAGCATATGATGTATAATAGAGTATACCCGTTACTTAAAAAGA
AGTCTGAAATGTTCGTTTTGTGGAAAAGAAACTAGTTAAATTTACTATTCCTAACCCGAATGAAATTAGCCTTTGCCTTATTCTGTGCAT
GGGTAAGTAACTTATTTCTGCACTGTTTTGTTGAACTTTGTGGAAACATTCTTTCGAGTTTGTTTTTGTCATTTTCGTAACAGTCGTCGA
ACTAGGCCTCAAAAACATACGTAACGAAAAGGCCTAGCGAGGCAAATTCTGATTGATTTGAATCTATATTTTTCTTTAAAAAGTCAAGGG
TTCTATATTGTGAGTAAATTAAATTTACATTTGAGTTGTTTGTTGCTAAGAGGTAGTAAATGTAAGAGAGTACTGGTTCCTTCAGTAGTG
AGTATTTCTCATAGTGCAGCTTTATTTATCTCCAGGATGTTTTTGTGGCTGTATTTGATTGATATGTGCTTCTTCTGATTCTTGCTAATT

>94239_94239_6_TRIP12-DNER_TRIP12_chr2_230642031_ENST00000389045_DNER_chr2_230456604_ENST00000341772_length(amino acids)=2143AA_BP=0
MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGSRRGSGLGKRGAAEARRQEKMADPESNQEAVNSSAARTDEAPQGAAASSSVAGAVGMT
TSGESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQASDESQQLQAVIEMCQLLVMGNEETLGGFP
VKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVDAIPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCL
LYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLV
VTPPILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCGASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVD
TMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIEAAHQVGEDEISLSTLGRVYTIDFNSMQQINEDTGTARAIQRKPNPLANSNTSG
YSESKKDDARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIASMLSSQDLKIVV
GALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAESESLLTSPPKACTNGSGSMGSTTSVSSGTATAATHAAADLGSPSLQHSRDDSLDL
SPQGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKSPTTTQSPKSSFLASLNPKTWGRLSTQSNSNNIEPARTAGGSGLARAASKD
TISNNREKIKGWIKEQAHKFVERYFSSENMDGSNPALNVLQRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLY
LTSKSEKDAVSREIRLKRFLHVFFSSPLPGEEPIGRVEPVGNAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGTGGSFSLNRGSQALKF
FNTHQLKCQLQRHPDCANVKQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGE
HLLPYNMTVYQAVRQFSIQAEDERESTDDESNPLGRAGIWTKTHTIWYKPVREDEESNKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHD
GVCPSVSNPLEVYLIPTPPENITFEDPSLDVILLLRVLHAISRYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTW
LTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNPEINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQY
ENEVGTGLGPTLEFYALVSQELQRADLGLWRGEEVTLSNPKGSQEGTKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMD
FRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQLVADPCASNPCHHGNCSSSSSSSSDGYLCICN
EGYEGPNCEQALPSLPATGWTESMAPRQLQPVPATQEPDKILPRSQATVTLPTWQPKTGQKVVEMKWDQVEVIPDIACGNASSNSSAGGR
LVSFEVPQNTSVKIRQDATASLILLWKVTATGFQQCSLIDGRSVTPLQASGGLVLLEEMLALGNNHFIGFVNDSVTKSIVALRLTLVVKV
STCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID
YCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRS
VGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFT
GEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSGHMAESLTNMPRHSLYIIIGALCVAFILMLIILIVGICRI

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Fusion Gene PPI Analysis for TRIP12-DNER


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneDNERchr2:230642030chr2:230456604ENST00000341772013677_68092.0738.0AP1G1 and somatodendritic targeting
TgeneDNERchr2:230642031chr2:230456604ENST00000341772013677_68092.0738.0AP1G1 and somatodendritic targeting


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneDNERchr2:230642030chr2:230456604ENST0000034177201344_13392.0738.0NOTCH1
TgeneDNERchr2:230642031chr2:230456604ENST0000034177201344_13392.0738.0NOTCH1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TRIP12-DNER


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TRIP12-DNER


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource