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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:TRIP12-MFI2 (FusionGDB2 ID:94244)

Fusion Gene Summary for TRIP12-MFI2

Fusion gene summary

Fusion gene information	Fusion gene name: TRIP12-MFI2
	Fusion gene ID: 94244
		Hgene	Tgene
	Gene symbol	TRIP12	MFI2
	Gene ID	9320	4241
	Gene name	thyroid hormone receptor interactor 12	melanotransferrin
	Synonyms	MRD49\|TRIP-12\|TRIPC\|ULF	CD228\|MAP97\|MFI2\|MTF1\|MTf
	Cytomap	2q36.3	3q29
	Type of gene	protein-coding	protein-coding
	Description	E3 ubiquitin-protein ligase TRIP12E3 ubiquitin-protein ligase for ArfHECT-type E3 ubiquitin transferase TRIP12TR-interacting protein 12probable E3 ubiquitin-protein ligase TRIP12thyroid receptor interacting protein 12	melanotransferrinantigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5melanoma-associated antigen p97membrane-bound transferrin-like protein
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000283943, ENST00000389044, ENST00000389045, ENST00000409677, ENST00000543084,	ENST00000296351, ENST00000296350,
Fusion gene scores	* DoF score	20 X 18 X 15=5400	5 X 6 X 5=150
	# samples	29	5
	** MAII score	log2(29/5400*10)=-4.21883460192326 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(5/150*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: TRIP12 [Title/Abstract] AND MFI2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	TRIP12(230642030)-MFI2(196730970), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	TRIP12	GO:0000209	protein polyubiquitination	30982744
Hgene	TRIP12	GO:0006511	ubiquitin-dependent protein catabolic process	18627766\|20208519\|30982744
Tgene	MFI2	GO:0010756	positive regulation of plasminogen activation	16713448
Tgene	MFI2	GO:0090091	positive regulation of extracellular matrix disassembly	16713448
Tgene	MFI2	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	16713448

Fusion gene breakpoints across TRIP12 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across MFI2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	OV	TCGA-13-1489	TRIP12	chr2	230642030	-	MFI2	chr3	196730970	-

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Fusion Gene ORF analysis for TRIP12-MFI2

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000283943	ENST00000296351	TRIP12	chr2	230642030	-	MFI2	chr3	196730970	-
5CDS-intron	ENST00000389044	ENST00000296351	TRIP12	chr2	230642030	-	MFI2	chr3	196730970	-
5CDS-intron	ENST00000389045	ENST00000296351	TRIP12	chr2	230642030	-	MFI2	chr3	196730970	-
In-frame	ENST00000283943	ENST00000296350	TRIP12	chr2	230642030	-	MFI2	chr3	196730970	-
In-frame	ENST00000389044	ENST00000296350	TRIP12	chr2	230642030	-	MFI2	chr3	196730970	-
In-frame	ENST00000389045	ENST00000296350	TRIP12	chr2	230642030	-	MFI2	chr3	196730970	-
intron-3CDS	ENST00000409677	ENST00000296350	TRIP12	chr2	230642030	-	MFI2	chr3	196730970	-
intron-3CDS	ENST00000543084	ENST00000296350	TRIP12	chr2	230642030	-	MFI2	chr3	196730970	-
intron-intron	ENST00000409677	ENST00000296351	TRIP12	chr2	230642030	-	MFI2	chr3	196730970	-
intron-intron	ENST00000543084	ENST00000296351	TRIP12	chr2	230642030	-	MFI2	chr3	196730970	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000283943	TRIP12	chr2	230642030	-	ENST00000296350	MFI2	chr3	196730970	-	7394	5483	179	5761	1860
ENST00000389045	TRIP12	chr2	230642030	-	ENST00000296350	MFI2	chr3	196730970	-	6478	4567	73	4845	1590
ENST00000389044	TRIP12	chr2	230642030	-	ENST00000296350	MFI2	chr3	196730970	-	7528	5617	169	5895	1908

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000283943	ENST00000296350	TRIP12	chr2	230642030	-	MFI2	chr3	196730970	-	0.000905947	0.999094
ENST00000389045	ENST00000296350	TRIP12	chr2	230642030	-	MFI2	chr3	196730970	-	0.00077306	0.9992269
ENST00000389044	ENST00000296350	TRIP12	chr2	230642030	-	MFI2	chr3	196730970	-	0.000820516	0.9991794

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Fusion Genomic Features for TRIP12-MFI2

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TRIP12-MFI2

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:230642030/chr3:196730970)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

TRIP12

chr2:230642030

chr3:196730970

ENST00000283943

749_836

1768

1993.0

Domain

WWE

Hgene

TRIP12

chr2:230642030

chr3:196730970

ENST00000389044

749_836

1816

2041.0

Domain

WWE

Hgene

TRIP12

chr2:230642030

chr3:196730970

ENST00000389045

749_836

1498

1723.0

Domain

WWE

Hgene

TRIP12

chr2:230642030

chr3:196730970

ENST00000283943

1496_1570

1768

1993.0

Region

Note=K-box

Hgene

TRIP12

chr2:230642030

chr3:196730970

ENST00000389044

1496_1570

1816

2041.0

Region

Note=K-box

Tgene

MFI2

chr2:230642030

chr3:196730970

ENST00000296351

23_357

303.0

Domain

Transferrin-like 1

Tgene

MFI2

chr2:230642030

chr3:196730970

ENST00000296351

366_706

303.0

Domain

Transferrin-like 2

Tgene

MFI2

chr2:230642030

chr3:196730970

ENST00000296351

20_30

303.0

Region

Note=Antigenic epitope

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

TRIP12

chr2:230642030

chr3:196730970

ENST00000283943

1885_1992

1768

1993.0

Domain

HECT

Hgene

TRIP12

chr2:230642030

chr3:196730970

ENST00000389044

1885_1992

1816

2041.0

Domain

HECT

Hgene

TRIP12

chr2:230642030

chr3:196730970

ENST00000389045

1885_1992

1498

1723.0

Domain

HECT

Hgene

TRIP12

chr2:230642030

chr3:196730970

ENST00000389045

1496_1570

1498

1723.0

Region

Note=K-box

Tgene

MFI2

chr2:230642030

chr3:196730970

ENST00000296350

23_357

646

739.0

Domain

Transferrin-like 1

Tgene

MFI2

chr2:230642030

chr3:196730970

ENST00000296350

366_706

646

739.0

Domain

Transferrin-like 2

Tgene

MFI2

chr2:230642030

chr3:196730970

ENST00000296350

20_30

646

739.0

Region

Note=Antigenic epitope

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Fusion Gene Sequence for TRIP12-MFI2

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>94244_94244_1_TRIP12-MFI2_TRIP12_chr2_230642030_ENST00000283943_MFI2_chr3_196730970_ENST00000296350_length(transcript)=7394nt_BP=5483nt
GCTGCGGCTCAGCTGATAATTGAAGGAACCCGGAGCCGCCGCCGCCGCGCCGCTGGGGGGGGTGGGGGGAGCTAGTGGAAGTTACTGCCG
CGCCACCGAGTCCGGACCGGAGACTTTGGGGCCTAACTAGTGAATGGTAGTGTCTAGAAAGGGTATGTCCCTTCAAGAGAGAGGTGCCAA
TGTCCAACCGGCCTAATAACAATCCAGGGGGGTCACTGCGACGTTCACAGAGGAACACTGCCGGGGCCCAACCACAAGACGACTCAATAG
GAGGAAGAAGCTGCAGTTCATCATCTGCTGTGATAGTTCCACAACCAGAGGATCCAGACAGAGCCAATACTTCAGAAAGACAAAAAACGG
GGCAGGTGCCTAAGAAAGACAATTCTCGAGGAGTGAAGCGCAGTGCTAGTCCAGACTACAACAGGACCAATTCTCCTAGCTCTGCAAAAA
AACCAAAAGCACTTCAGCATACTGAATCTCCCTCAGAAACAAATAAGCCACATAGTAAGTCAAAGAAGAGACATTTAGACCAGGAGCAAC
AACTGAAATCTGCACAATCACCATCAACAAGCAAGGCTCATACCAGGAAGAGTGGGGCCACTGGCGGTTCACGGAGTCAGAAAAGAAAAA
GGACAGAGAGTTCTTGTGTAAAGAGTGGCTCCGGGTCTGAATCAACTGGTGCAGAAGAGAGATCTGCGAAACCTACCAAGCTGGCTTCAA
AATCAGCCACCTCAGCCAAAGCTGGGTGTAGCACCATCACTGATTCTTCTTCTGCTGCCTCTACTTCCTCCTCGTCTTCTGCTGTAGCCT
CGGCCTCCTCCACTGTACCACCAGGTGCCAGAGTGAAACAAGGAAAAGATCAGAACAAGGCCAGGCGTTCCCGTTCAGCGTCCAGTCCCA
GCCCCAGAAGAAGTAGCAGGGAAAAGGAACAGAGTAAAACTGGTGGCTCTTCAAAATTTGATTGGGCTGCTCGTTTCAGCCCTAAAGTTA
GCCTTCCTAAAACAAAACTGTCTCTTCCAGGGTCTTCTAAGTCAGAGACATCAAAACCTGGACCTTCTGGATTACAGGCCAAATTAGCAA
GTTTAAGAAAATCTACGAAGAAACGCAGTGAGTCTCCACCTGCTGAGCTCCCCAGTTTGAGGCGGAGCACACGCCAAAAGACCACGGGCT
CCTGTGCTAGTACCAGTCGGCGAGGCTCTGGCCTGGGCAAAAGAGGAGCAGCTGAAGCTCGTCGACAGGAGAAAATGGCAGACCCTGAAA
GCAACCAGGAGGCAGTAAATTCTTCAGCTGCTCGGACAGATGAAGCTCCCCAAGGAGCTGCAGGGGCTGTTGGCATGACCACCTCTGGGG
AGAGTGAATCAGATGATTCCGAGATGGGACGTTTGCAAGCTTTGTTAGAGGCAAGGGGTCTTCCCCCTCACCTATTTGGTCCTCTTGGTC
CTCGGATGTCACAGCTTTTCCATAGAACAATTGGAAGTGGAGCTAGTTCTAAGGCCCAGCAGCTACTACAAGGATTGCAAGCCAGTGATG
AAAGTCAACAGCTTCAGGCAGTTATTGAGATGTGTCAGTTACTGGTCATGGGAAATGAGGAGACACTGGGAGGGTTTCCTGTCAAGAGTG
TTGTTCCAGCTTTGATTACGTTACTTCAGATGGAGCACAATTTTGATATTATGAACCATGCTTGTCGAGCCTTAACATACATGATGGAAG
CACTTCCTCGATCTTCTGCTGTTGTAGTAGATGCTATTCCTGTCTTTTTAGAAAAGCTGCAAGTTATTCAGTGTATTGATGTGGCAGAGC
AGGCCTTGACTGCCTTGGAGATGTTGTCACGGAGACATAGTAAAGCCATTCTACAGGCGGGTGGTTTGGCAGACTGCTTGCTGTACCTAG
AATTCTTCAGCATAAATGCCCAAAGAAATGCATTAGCAATTGCAGCTAATTGCTGCCAGAGTATCACGCCAGATGAATTTCATTTTGTGG
CAGATTCACTCCCATTGCTAACCCAAAGGCTAACACATCAGGATAAAAAGTCAGTAGAAAGCACTTGCCTTTGTTTTGCACGCCTAGTGG
ACAACTTCCAGCATGAGGAGAATTTACTCCAGCAGGTTGCTTCCAAAGATCTGCTTACAAATGTTCAACAGCTGTTGGTAGTGACTCCAC
CCATTTTAAGTTCTGGGATGTTTATAATGGTGGTTCGCATGTTTTCTCTGATGTGTTCCAACTGTCCAACTTTAGCTGTTCAACTTATGA
AACAAAACATTGCAGAAACGCTTCACTTTCTCCTGTGTGGTGCCTCCAATGGAAGTTGTCAGGAACAGATTGATCTTGTTCCACGAAGCC
CTCAAGAGTTGTATGAACTGACATCTCTGATTTGTGAACTTATGCCATGTTTACCAAAAGAAGGCATTTTTGCAGTTGATACCATGTTGA
AGAAGGGAAATGCACAGAACACAGATGGTGCGATATGGCAGTGGCGTGATGATCGGGGCCTCTGGCATCCATATAACAGGATTGACAGCC
GGATCATTGAGCAAATCAATGAGGACACGGGAACAGCACGTGCCATTCAGAGAAAACCTAACCCGTTAGCCAATAGTAACACTAGTGGAT
ATTCAGAGTCAAAGAAGGATGATGCTCGAGCACAGCTTATGAAAGAGGATCCGGAACTGGCTAAGTCTTTTATTAAGACATTATTTGGTG
TTCTTTATGAAGTGTATAGTTCCTCAGCAGGACCTGCGGTCAGACATAAGTGCCTTAGAGCAATTCTTAGGATAATTTATTTTGCGGATG
CTGAACTTCTGAAGGATGTTCTGAAAAATCATGCTGTTTCAAGTCACATTGCTTCCATGCTGTCAAGCCAAGACCTGAAGATAGTAGTGG
GAGCACTTCAGATGGCAGAAATTTTAATGCAGAAGTTACCTGATATTTTTAGTGTTTACTTCAGAAGAGAAGGTGTAATGCATCAAGTAA
AACACTTAGCAGAATCAGAGTCTTTGTTGACAAGTCCACCAAAGGCATGTACGAATGGATCGGGATCCATGGGATCCACAACTTCAGTCA
GCAGTGGGACAGCCACAGCTGCCACTCATGCTGCAGCTGACTTGGGATCACCCAGCTTGCAGCACAGCAGGGATGATTCTTTAGATCTCA
GCCCTCAAGGTCGATTAAGTGATGTTCTAAAGAGAAAACGACTGCCAAAACGAGGGCCAAGAAGGCCAAAGTACTCACCTCCAAGAGATG
ATGACAAAGTAGACAATCAAGCTAAAAGCCCCACCACTACTCAGTCACCTAAATCTTCTTTCCTGGCAAGCTTGAATCCAAAAACATGGG
GAAGGTTAAGTACACAGTCCAACAGCAACAACATTGAGCCAGCACGGACTGCGGGAGGTAGTGGCCTTGCCAGGGCTGCCTCAAAGGATA
CCATCTCCAATAATAGAGAAAAAATTAAAGGTTGGATTAAGGAGCAGGCACATAAATTTGTAGAACGTTATTTCAGTTCTGAGAATATGG
ATGGAAGCAACCCTGCATTGAATGTCCTTCAGAGACTTTGTGCTGCAACCGAACAACTCAACCTCCAGGTGGATGGTGGAGCTGAGTGCC
TTGTAGAAATCCGTAGCATAGTCTCAGAGTCAGATGTTTCATCATTTGAAATCCAACATAGTGGATTTGTGAAGCAGCTGTTGCTTTATT
TGACATCTAAAAGTGAAAAGGATGCTGTGAGCAGAGAGATCAGATTAAAGCGATTTCTTCATGTATTTTTTTCTTCTCCACTTCCTGGAG
AAGAGCCCATTGGAAGAGTGGAACCAGTGGGTAATGCACCTTTGTTGGCATTAGTTCACAAGATGAACAACTGCCTCAGCCAGATGGAAC
AATTTCCAGTCAAAGTACATGATTTCCCTAGTGGAAATGGGACAGGAGGCAGCTTTTCTCTCAACAGAGGATCACAGGCTTTAAAATTTT
TCAACACACATCAATTAAAATGCCAGTTACAAAGGCATCCAGACTGTGCAAATGTGAAGCAGTGGAAGGGTGGACCTGTCAAGATTGACC
CTCTGGCTTTGGTACAAGCCATCGAGAGATACCTTGTAGTTAGAGGGTATGGAAGAGTAAGAGAAGATGATGAAGACAGCGATGACGATG
GATCAGATGAGGAAATAGATGAGTCTCTGGCTGCTCAGTTCCTAAATTCAGGAAATGTAAGACACAGGCTGCAGTTTTATATTGGAGAAC
ATTTGCTGCCGTATAACATGACTGTGTATCAGGCAGTACGGCAGTTTAGTATACAGGCTGAAGATGAAAGAGAATCCACAGATGATGAGA
GCAATCCTCTAGGCAGAGCTGGTATTTGGACAAAGACTCATACAATATGGTATAAACCTGTGAGAGAGGATGAAGAAAGTAATAAAGATT
GTGTTGGTGGTAAAAGAGGAAGAGCCCAAACAGCTCCAACGAAAACTTCCCCTAGAAATGCAAAAAAGCATGATGAGTTATGGCACGATG
GAGTGTGCCCATCAGTATCAAATCCTTTAGAAGTTTACCTCATTCCCACACCACCTGAAAATATAACATTTGAAGACCCGTCATTAGATG
TGATCCTTCTTTTAAGAGTTTTACATGCTATCAGTCGATACTGGTATTACTTGTATGATAATGCAATGTGCAAGGAAATTATTCCAACTA
GTGAATTTATTAACAGTAAGTTAACAGCAAAAGCAAATAGGCAACTTCAAGATCCTTTAGTAATCATGACAGGAAACATCCCAACATGGC
TTACTGAGCTAGGAAAAACCTGCCCATTTTTCTTTCCTTTTGATACCCGGCAAATGCTTTTTTATGTAACTGCATTTGATCGGGACCGAG
CAATGCAAAGATTACTTGATACCAACCCAGAAATCAACCAGTCTGATTCTCAAGATAGCAGAGTTGCACCTAGATTGGATAGAAAAAAAC
GTACTGTGAACCGAGAGGAGCTGCTGAAACAGGCGGAGTCTGTGATGCAGGACCTCGGCAGCTCACGGGCCATGTTAGAAATCCAGTATG
AAAATGAGGTTGGTACAGGTCTTGGGCCTACACTGGAGTTTTATGCGCTTGTATCTCAGGAACTACAGAGAGCTGACTTGGGTCTTTGGA
GAGGTGAAGAAGTAACTCTTAGCAATCCAAAAGGGAGCCAAGAAGGGACCAAGTATATTCAAAACCTCCAGGGCCTGTTTGCGCTTCCCT
TTGGTAGGACAGCAAAGCCAGCTCATATCGCAAAGGTTAAGATGAAGTTTCGCTTCTTAGGAAAATTAATGGCCAAGGCTATCATGGATT
TCAGATTGGTGGACCTTCCCCTTGGCTTACCCTTTTATAAATGGATGCTACGGCAAGAAACTTCACTGACATCACACGATTTGTTTGACA
TCGACCCAGTTGTAGCCAGATCAGTTTATCACCTAGAAGACATTGTCAGACAGAAGAAAAGACTTGAACAAGATAAATCCCAGGACCTGT
TTGGAGACGACCACAATAAGAACGGGTTCAAAATGTTCGACTCCTCCAACTATCATGGCCAAGACCTGCTTTTCAAGGATGCCACCGTCC
GGGCGGTGCCTGTCGGAGAGAAAACCACCTACCGCGGCTGGCTGGGGCTGGACTACGTGGCGGCGCTGGAAGGGATGTCGTCTCAGCAGT
GCTCGGGCGCAGCGGCCCCGGCGCCCGGGGCGCCCCTGCTCCCGCTGCTGCTGCCCGCCCTCGCCGCCCGCCTGCTCCCGCCCGCCCTCT
GAGCCCGGCCGCCCCGCCCCAGAGCTCCGATGCCCGCCCGGGGAGTTTCCGCGGCGGCTTCGCGCTGGAATCCAGAAGGAAGCTCGCGAA
GGCCGGGCCCGGCGTGGGCGGGAGCAGGCGCCTCCCCGGGAGCCCCGCCGCCCACGGGCGCCACCTGGCGCTGCTACCTGAGGCGCCGCC
CCCGGGCCCGCGCGGCCCTTCCCGCCAACCGCCGCCTCCCGCCACCTGGAGCCGCGCGGGCCGCGCCGGAGGAGGCCGGTTGCCCAGGAA
ACCGCTGAGTCCGGGCTTCCCGCCGCCCGCCCCGCGGTGTCGCCCGAGGGGCCCGCCCGCCTCCTCCCCGCAGCCCCGCGCCCCCGTCCG
CGAGGCCCCCTGGGGACGCGGTGGCCGCCGAGGCGCCTACACCCGCAGGCCGCGGCCAGGCCGTCCCAGGAGGCCCCGGCGCCAACGGGA
CCCGGCGCGTGGGACAGCGGCCTCTGCTGGCGGCGGCGGGAGGGAGGCCGGACCGGGGCGACGGGGAGAAGCCTTCGCCCGCGGGACCGT
GTCCGGGGTGGGGGCTCCAGTTCCTCCGACCGCCCGTGCGCTGGGAGGGAGGCCGAGCCCGGGGAACGCCGCGTGCCCTGCCTCGTCCCC
CACTGTGGCCGCGCCAGCTCCATCCCGGGCCAGCCGCGTCCACGGGCCCCCTCCCGAGTCTCCTCAGGCTCTCGCCTCCCCTACCCCCGT
GGGATGCCCACCGCCCGCACCCACGCCCGAGCCTGGCGGCAGCAGCCGCCCCCCGCCTGAAGGGAGCCGGAGGTGACCCAGGCCGCGGGC
TCCCGAGGCCCCTGAAGGGCTGCGCGTGGGGACCCGCCATGCTTCTGGGTTCCGAACGGGGGTGAGCTCCGTCTCCTCACCCGGCCCCGC
ACCCGCTGGGCCTGGGGACCCCTCACTCCCCGTGCCCGCCCCTCCGCGAGGCAGCAGAAAGCGCCCGGCCGGGGCCTCTCTCTACTCCAT
CTTGCCACAGTTGTCTGAGAAGCCAGAAAAAGTTTCCAGAACTGGCAGCCCTTAAAAAAAATGAAGAGGAAGAGAAGAAATGGGAGCAGG
CAGCCCTCGTCAGCAGACCGGGAGCCGCGTGGGCGCGGAGCCATTTGCATTCCGGTCTGCGGGGGCTCGGGGATGCTGGTGACAGGCCCG
GTTCCCGGTGGCTCGCCCCCACCTGCGGGCGTCGGGAAGGATCCCTTCCATCTCTCAGCCGCAGAGGAGGCCCTGGCAGCGCCCCGGCTG
TAGCCATGCAACCCCGAGGAGTCCCGGGCACCTTCACCCCACCGGGAGGGGCCACAAGGACCTGGGCCTCGGCCACCAAGCTTTGTCCCC
TCTCGCTGTGGGGGGCTAGTGATTCTCCTCCGACCTGACGATTGCTTGGTTTTTTCAAAAGGGAGTTTTGTGCGGTGAGAAGTGTGTTTC
TGTGTGGCTAACTCTGGGCTAGCGTGCCGTGGCCATTGAAGGTGTGGCCTGCGTGGGTGCAGTGTAAGTGACGCTGGATTGTCAGGTGGC
AGCAGGGGACCCCTGCTGTGTCAGTGCTAATGAAACATGTTGGTTGGTTTCTAAAATAAAGCCAAACAAGCCAGCACATGCAGAGGCTTG

>94244_94244_1_TRIP12-MFI2_TRIP12_chr2_230642030_ENST00000283943_MFI2_chr3_196730970_ENST00000296350_length(amino acids)=1860AA_BP=1767
MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGRSCSSSSAVIVPQPEDPDRANTSERQKTGQVPKKDNSRGVKRSASPDYNRTNSPSSAK
KPKALQHTESPSETNKPHSKSKKRHLDQEQQLKSAQSPSTSKAHTRKSGATGGSRSQKRKRTESSCVKSGSGSESTGAEERSAKPTKLAS
KSATSAKAGCSTITDSSSAASTSSSSSAVASASSTVPPGARVKQGKDQNKARRSRSASSPSPRRSSREKEQSKTGGSSKFDWAARFSPKV
SLPKTKLSLPGSSKSETSKPGPSGLQAKLASLRKSTKKRSESPPAELPSLRRSTRQKTTGSCASTSRRGSGLGKRGAAEARRQEKMADPE
SNQEAVNSSAARTDEAPQGAAGAVGMTTSGESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQASD
ESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVDAIPVFLEKLQVIQCIDVAE
QALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLV
DNFQHEENLLQQVASKDLLTNVQQLLVVTPPILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCGASNGSCQEQIDLVPRS
PQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIEQINEDTGTARAIQRKPNPLANSNTSG
YSESKKDDARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIASMLSSQDLKIVV
GALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAESESLLTSPPKACTNGSGSMGSTTSVSSGTATAATHAAADLGSPSLQHSRDDSLDL
SPQGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKSPTTTQSPKSSFLASLNPKTWGRLSTQSNSNNIEPARTAGGSGLARAASKD
TISNNREKIKGWIKEQAHKFVERYFSSENMDGSNPALNVLQRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLY
LTSKSEKDAVSREIRLKRFLHVFFSSPLPGEEPIGRVEPVGNAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGTGGSFSLNRGSQALKF
FNTHQLKCQLQRHPDCANVKQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGE
HLLPYNMTVYQAVRQFSIQAEDERESTDDESNPLGRAGIWTKTHTIWYKPVREDEESNKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHD
GVCPSVSNPLEVYLIPTPPENITFEDPSLDVILLLRVLHAISRYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTW
LTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNPEINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQY
ENEVGTGLGPTLEFYALVSQELQRADLGLWRGEEVTLSNPKGSQEGTKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMD
FRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQDLFGDDHNKNGFKMFDSSNYHGQDLLFKDATV

--------------------------------------------------------------
>94244_94244_2_TRIP12-MFI2_TRIP12_chr2_230642030_ENST00000389044_MFI2_chr3_196730970_ENST00000296350_length(transcript)=7528nt_BP=5617nt
AGCTGATAATTGAAGGAACCCGGAGCCGCCGCCGCCGCGCCGCTGGGGGGGGTGGGGGGAGCTAGTGGAAGTTACTGCCGCGCCACCGAG
TCCGGACCGGAGACTTTGGGGCCTAACTAGTGAATGGTAGTGTCTAGAAAGGGTATGTCCCTTCAAGAGAGAGGTGCCAATGTCCAACCG
GCCTAATAACAATCCAGGGGGGTCACTGCGACGTTCACAGAGGAACACTGCCGGGGCCCAACCACAAGACGACTCAATAGGAGGAAGGTC
ACATTTAGGGCAGGCAAAACATAAGGGATATAGCCCTCCTGAGAGTAGAAAATCTAATTCTAAGGCACCCAAAGTGCAGTCTAATACTAC
TTCTGAACTGTCAAGGGGACACCTTTCTAAAAGAAGCTGCAGTTCATCATCTGCTGTGATAGTTCCACAACCAGAGGATCCAGACAGAGC
CAATACTTCAGAAAGACAAAAAACGGGGCAGGTGCCTAAGAAAGACAATTCTCGAGGAGTGAAGCGCAGTGCTAGTCCAGACTACAACAG
GACCAATTCTCCTAGCTCTGCAAAAAAACCAAAAGCACTTCAGCATACTGAATCTCCCTCAGAAACAAATAAGCCACATAGTAAGTCAAA
GAAGAGACATTTAGACCAGGAGCAACAACTGAAATCTGCACAATCACCATCAACAAGCAAGGCTCATACCAGGAAGAGTGGGGCCACTGG
CGGTTCACGGAGTCAGAAAAGAAAAAGGACAGAGAGTTCTTGTGTAAAGAGTGGCTCCGGGTCTGAATCAACTGGTGCAGAAGAGAGATC
TGCGAAACCTACCAAGCTGGCTTCAAAATCAGCCACCTCAGCCAAAGCTGGGTGTAGCACCATCACTGATTCTTCTTCTGCTGCCTCTAC
TTCCTCCTCGTCTTCTGCTGTAGCCTCGGCCTCCTCCACTGTACCACCAGGTGCCAGAGTGAAACAAGGAAAAGATCAGAACAAGGCCAG
GCGTTCCCGTTCAGCGTCCAGTCCCAGCCCCAGAAGAAGTAGCAGGGAAAAGGAACAGAGTAAAACTGGTGGCTCTTCAAAATTTGATTG
GGCTGCTCGTTTCAGCCCTAAAGTTAGCCTTCCTAAAACAAAACTGTCTCTTCCAGGGTCTTCTAAGTCAGAGACATCAAAACCTGGACC
TTCTGGATTACAGGCCAAATTAGCAAGTTTAAGAAAATCTACGAAGAAACGCAGTGAGTCTCCACCTGCTGAGCTCCCCAGTTTGAGGCG
GAGCACACGCCAAAAGACCACGGGCTCCTGTGCTAGTACCAGTCGGCGAGGCTCTGGCCTGGGCAAAAGAGGAGCAGCTGAAGCTCGTCG
ACAGGAGAAAATGGCAGACCCTGAAAGCAACCAGGAGGCAGTAAATTCTTCAGCTGCTCGGACAGATGAAGCTCCCCAAGGAGCTGCAGC
CTCTAGTTCTGTTGCAGGGGCTGTTGGCATGACCACCTCTGGGGAGAGTGAATCAGATGATTCCGAGATGGGACGTTTGCAAGCTTTGTT
AGAGGCAAGGGGTCTTCCCCCTCACCTATTTGGTCCTCTTGGTCCTCGGATGTCACAGCTTTTCCATAGAACAATTGGAAGTGGAGCTAG
TTCTAAGGCCCAGCAGCTACTACAAGGATTGCAAGCCAGTGATGAAAGTCAACAGCTTCAGGCAGTTATTGAGATGTGTCAGTTACTGGT
CATGGGAAATGAGGAGACACTGGGAGGGTTTCCTGTCAAGAGTGTTGTTCCAGCTTTGATTACGTTACTTCAGATGGAGCACAATTTTGA
TATTATGAACCATGCTTGTCGAGCCTTAACATACATGATGGAAGCACTTCCTCGATCTTCTGCTGTTGTAGTAGATGCTATTCCTGTCTT
TTTAGAAAAGCTGCAAGTTATTCAGTGTATTGATGTGGCAGAGCAGGCCTTGACTGCCTTGGAGATGTTGTCACGGAGACATAGTAAAGC
CATTCTACAGGCGGGTGGTTTGGCAGACTGCTTGCTGTACCTAGAATTCTTCAGCATAAATGCCCAAAGAAATGCATTAGCAATTGCAGC
TAATTGCTGCCAGAGTATCACGCCAGATGAATTTCATTTTGTGGCAGATTCACTCCCATTGCTAACCCAAAGGCTAACACATCAGGATAA
AAAGTCAGTAGAAAGCACTTGCCTTTGTTTTGCACGCCTAGTGGACAACTTCCAGCATGAGGAGAATTTACTCCAGCAGGTTGCTTCCAA
AGATCTGCTTACAAATGTTCAACAGCTGTTGGTAGTGACTCCACCCATTTTAAGTTCTGGGATGTTTATAATGGTGGTTCGCATGTTTTC
TCTGATGTGTTCCAACTGTCCAACTTTAGCTGTTCAACTTATGAAACAAAACATTGCAGAAACGCTTCACTTTCTCCTGTGTGGTGCCTC
CAATGGAAGTTGTCAGGAACAGATTGATCTTGTTCCACGAAGCCCTCAAGAGTTGTATGAACTGACATCTCTGATTTGTGAACTTATGCC
ATGTTTACCAAAAGAAGGCATTTTTGCAGTTGATACCATGTTGAAGAAGGGAAATGCACAGAACACAGATGGTGCGATATGGCAGTGGCG
TGATGATCGGGGCCTCTGGCATCCATATAACAGGATTGACAGCCGGATCATTGAGCAAATCAATGAGGACACGGGAACAGCACGTGCCAT
TCAGAGAAAACCTAACCCGTTAGCCAATAGTAACACTAGTGGATATTCAGAGTCAAAGAAGGATGATGCTCGAGCACAGCTTATGAAAGA
GGATCCGGAACTGGCTAAGTCTTTTATTAAGACATTATTTGGTGTTCTTTATGAAGTGTATAGTTCCTCAGCAGGACCTGCGGTCAGACA
TAAGTGCCTTAGAGCAATTCTTAGGATAATTTATTTTGCGGATGCTGAACTTCTGAAGGATGTTCTGAAAAATCATGCTGTTTCAAGTCA
CATTGCTTCCATGCTGTCAAGCCAAGACCTGAAGATAGTAGTGGGAGCACTTCAGATGGCAGAAATTTTAATGCAGAAGTTACCTGATAT
TTTTAGTGTTTACTTCAGAAGAGAAGGTGTAATGCATCAAGTAAAACACTTAGCAGAATCAGAGTCTTTGTTGACAAGTCCACCAAAGGC
ATGTACGAATGGATCGGGATCCATGGGATCCACAACTTCAGTCAGCAGTGGGACAGCCACAGCTGCCACTCATGCTGCAGCTGACTTGGG
ATCACCCAGCTTGCAGCACAGCAGGGATGATTCTTTAGATCTCAGCCCTCAAGGTCGATTAAGTGATGTTCTAAAGAGAAAACGACTGCC
AAAACGAGGGCCAAGAAGGCCAAAGTACTCACCTCCAAGAGATGATGACAAAGTAGACAATCAAGCTAAAAGCCCCACCACTACTCAGTC
ACCTAAATCTTCTTTCCTGGCAAGCTTGAATCCAAAAACATGGGGAAGGTTAAGTACACAGTCCAACAGCAACAACATTGAGCCAGCACG
GACTGCGGGAGGTAGTGGCCTTGCCAGGGCTGCCTCAAAGGATACCATCTCCAATAATAGAGAAAAAATTAAAGGTTGGATTAAGGAGCA
GGCACATAAATTTGTAGAACGTTATTTCAGTTCTGAGAATATGGATGGAAGCAACCCTGCATTGAATGTCCTTCAGAGACTTTGTGCTGC
AACCGAACAACTCAACCTCCAGGTGGATGGTGGAGCTGAGTGCCTTGTAGAAATCCGTAGCATAGTCTCAGAGTCAGATGTTTCATCATT
TGAAATCCAACATAGTGGATTTGTGAAGCAGCTGTTGCTTTATTTGACATCTAAAAGTGAAAAGGATGCTGTGAGCAGAGAGATCAGATT
AAAGCGATTTCTTCATGTATTTTTTTCTTCTCCACTTCCTGGAGAAGAGCCCATTGGAAGAGTGGAACCAGTGGGTAATGCACCTTTGTT
GGCATTAGTTCACAAGATGAACAACTGCCTCAGCCAGATGGAACAATTTCCAGTCAAAGTACATGATTTCCCTAGTGGAAATGGGACAGG
AGGCAGCTTTTCTCTCAACAGAGGATCACAGGCTTTAAAATTTTTCAACACACATCAATTAAAATGCCAGTTACAAAGGCATCCAGACTG
TGCAAATGTGAAGCAGTGGAAGGGTGGACCTGTCAAGATTGACCCTCTGGCTTTGGTACAAGCCATCGAGAGATACCTTGTAGTTAGAGG
GTATGGAAGAGTAAGAGAAGATGATGAAGACAGCGATGACGATGGATCAGATGAGGAAATAGATGAGTCTCTGGCTGCTCAGTTCCTAAA
TTCAGGAAATGTAAGACACAGGCTGCAGTTTTATATTGGAGAACATTTGCTGCCGTATAACATGACTGTGTATCAGGCAGTACGGCAGTT
TAGTATACAGGCTGAAGATGAAAGAGAATCCACAGATGATGAGAGCAATCCTCTAGGCAGAGCTGGTATTTGGACAAAGACTCATACAAT
ATGGTATAAACCTGTGAGAGAGGATGAAGAAAGTAATAAAGATTGTGTTGGTGGTAAAAGAGGAAGAGCCCAAACAGCTCCAACGAAAAC
TTCCCCTAGAAATGCAAAAAAGCATGATGAGTTATGGCACGATGGAGTGTGCCCATCAGTATCAAATCCTTTAGAAGTTTACCTCATTCC
CACACCACCTGAAAATATAACATTTGAAGACCCGTCATTAGATGTGATCCTTCTTTTAAGAGTTTTACATGCTATCAGTCGATACTGGTA
TTACTTGTATGATAATGCAATGTGCAAGGAAATTATTCCAACTAGTGAATTTATTAACAGTAAGTTAACAGCAAAAGCAAATAGGCAACT
TCAAGATCCTTTAGTAATCATGACAGGAAACATCCCAACATGGCTTACTGAGCTAGGAAAAACCTGCCCATTTTTCTTTCCTTTTGATAC
CCGGCAAATGCTTTTTTATGTAACTGCATTTGATCGGGACCGAGCAATGCAAAGATTACTTGATACCAACCCAGAAATCAACCAGTCTGA
TTCTCAAGATAGCAGAGTTGCACCTAGATTGGATAGAAAAAAACGTACTGTGAACCGAGAGGAGCTGCTGAAACAGGCGGAGTCTGTGAT
GCAGGACCTCGGCAGCTCACGGGCCATGTTAGAAATCCAGTATGAAAATGAGGTTGGTACAGGTCTTGGGCCTACACTGGAGTTTTATGC
GCTTGTATCTCAGGAACTACAGAGAGCTGACTTGGGTCTTTGGAGAGGTGAAGAAGTAACTCTTAGCAATCCAAAAGGGAGCCAAGAAGG
GACCAAGTATATTCAAAACCTCCAGGGCCTGTTTGCGCTTCCCTTTGGTAGGACAGCAAAGCCAGCTCATATCGCAAAGGTTAAGATGAA
GTTTCGCTTCTTAGGAAAATTAATGGCCAAGGCTATCATGGATTTCAGATTGGTGGACCTTCCCCTTGGCTTACCCTTTTATAAATGGAT
GCTACGGCAAGAAACTTCACTGACATCACACGATTTGTTTGACATCGACCCAGTTGTAGCCAGATCAGTTTATCACCTAGAAGACATTGT
CAGACAGAAGAAAAGACTTGAACAAGATAAATCCCAGGACCTGTTTGGAGACGACCACAATAAGAACGGGTTCAAAATGTTCGACTCCTC
CAACTATCATGGCCAAGACCTGCTTTTCAAGGATGCCACCGTCCGGGCGGTGCCTGTCGGAGAGAAAACCACCTACCGCGGCTGGCTGGG
GCTGGACTACGTGGCGGCGCTGGAAGGGATGTCGTCTCAGCAGTGCTCGGGCGCAGCGGCCCCGGCGCCCGGGGCGCCCCTGCTCCCGCT
GCTGCTGCCCGCCCTCGCCGCCCGCCTGCTCCCGCCCGCCCTCTGAGCCCGGCCGCCCCGCCCCAGAGCTCCGATGCCCGCCCGGGGAGT
TTCCGCGGCGGCTTCGCGCTGGAATCCAGAAGGAAGCTCGCGAAGGCCGGGCCCGGCGTGGGCGGGAGCAGGCGCCTCCCCGGGAGCCCC
GCCGCCCACGGGCGCCACCTGGCGCTGCTACCTGAGGCGCCGCCCCCGGGCCCGCGCGGCCCTTCCCGCCAACCGCCGCCTCCCGCCACC
TGGAGCCGCGCGGGCCGCGCCGGAGGAGGCCGGTTGCCCAGGAAACCGCTGAGTCCGGGCTTCCCGCCGCCCGCCCCGCGGTGTCGCCCG
AGGGGCCCGCCCGCCTCCTCCCCGCAGCCCCGCGCCCCCGTCCGCGAGGCCCCCTGGGGACGCGGTGGCCGCCGAGGCGCCTACACCCGC
AGGCCGCGGCCAGGCCGTCCCAGGAGGCCCCGGCGCCAACGGGACCCGGCGCGTGGGACAGCGGCCTCTGCTGGCGGCGGCGGGAGGGAG
GCCGGACCGGGGCGACGGGGAGAAGCCTTCGCCCGCGGGACCGTGTCCGGGGTGGGGGCTCCAGTTCCTCCGACCGCCCGTGCGCTGGGA
GGGAGGCCGAGCCCGGGGAACGCCGCGTGCCCTGCCTCGTCCCCCACTGTGGCCGCGCCAGCTCCATCCCGGGCCAGCCGCGTCCACGGG
CCCCCTCCCGAGTCTCCTCAGGCTCTCGCCTCCCCTACCCCCGTGGGATGCCCACCGCCCGCACCCACGCCCGAGCCTGGCGGCAGCAGC
CGCCCCCCGCCTGAAGGGAGCCGGAGGTGACCCAGGCCGCGGGCTCCCGAGGCCCCTGAAGGGCTGCGCGTGGGGACCCGCCATGCTTCT
GGGTTCCGAACGGGGGTGAGCTCCGTCTCCTCACCCGGCCCCGCACCCGCTGGGCCTGGGGACCCCTCACTCCCCGTGCCCGCCCCTCCG
CGAGGCAGCAGAAAGCGCCCGGCCGGGGCCTCTCTCTACTCCATCTTGCCACAGTTGTCTGAGAAGCCAGAAAAAGTTTCCAGAACTGGC
AGCCCTTAAAAAAAATGAAGAGGAAGAGAAGAAATGGGAGCAGGCAGCCCTCGTCAGCAGACCGGGAGCCGCGTGGGCGCGGAGCCATTT
GCATTCCGGTCTGCGGGGGCTCGGGGATGCTGGTGACAGGCCCGGTTCCCGGTGGCTCGCCCCCACCTGCGGGCGTCGGGAAGGATCCCT
TCCATCTCTCAGCCGCAGAGGAGGCCCTGGCAGCGCCCCGGCTGTAGCCATGCAACCCCGAGGAGTCCCGGGCACCTTCACCCCACCGGG
AGGGGCCACAAGGACCTGGGCCTCGGCCACCAAGCTTTGTCCCCTCTCGCTGTGGGGGGCTAGTGATTCTCCTCCGACCTGACGATTGCT
TGGTTTTTTCAAAAGGGAGTTTTGTGCGGTGAGAAGTGTGTTTCTGTGTGGCTAACTCTGGGCTAGCGTGCCGTGGCCATTGAAGGTGTG
GCCTGCGTGGGTGCAGTGTAAGTGACGCTGGATTGTCAGGTGGCAGCAGGGGACCCCTGCTGTGTCAGTGCTAATGAAACATGTTGGTTG

>94244_94244_2_TRIP12-MFI2_TRIP12_chr2_230642030_ENST00000389044_MFI2_chr3_196730970_ENST00000296350_length(amino acids)=1908AA_BP=1815
MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGRSHLGQAKHKGYSPPESRKSNSKAPKVQSNTTSELSRGHLSKRSCSSSSAVIVPQPED
PDRANTSERQKTGQVPKKDNSRGVKRSASPDYNRTNSPSSAKKPKALQHTESPSETNKPHSKSKKRHLDQEQQLKSAQSPSTSKAHTRKS
GATGGSRSQKRKRTESSCVKSGSGSESTGAEERSAKPTKLASKSATSAKAGCSTITDSSSAASTSSSSSAVASASSTVPPGARVKQGKDQ
NKARRSRSASSPSPRRSSREKEQSKTGGSSKFDWAARFSPKVSLPKTKLSLPGSSKSETSKPGPSGLQAKLASLRKSTKKRSESPPAELP
SLRRSTRQKTTGSCASTSRRGSGLGKRGAAEARRQEKMADPESNQEAVNSSAARTDEAPQGAAASSSVAGAVGMTTSGESESDDSEMGRL
QALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQASDESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQME
HNFDIMNHACRALTYMMEALPRSSAVVVDAIPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNAL
AIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLVVTPPILSSGMFIMVV
RMFSLMCSNCPTLAVQLMKQNIAETLHFLLCGASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAI
WQWRDDRGLWHPYNRIDSRIIEQINEDTGTARAIQRKPNPLANSNTSGYSESKKDDARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGP
AVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIASMLSSQDLKIVVGALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAESESLLTS
PPKACTNGSGSMGSTTSVSSGTATAATHAAADLGSPSLQHSRDDSLDLSPQGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKSPT
TTQSPKSSFLASLNPKTWGRLSTQSNSNNIEPARTAGGSGLARAASKDTISNNREKIKGWIKEQAHKFVERYFSSENMDGSNPALNVLQR
LCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKSEKDAVSREIRLKRFLHVFFSSPLPGEEPIGRVEPVGN
APLLALVHKMNNCLSQMEQFPVKVHDFPSGNGTGGSFSLNRGSQALKFFNTHQLKCQLQRHPDCANVKQWKGGPVKIDPLALVQAIERYL
VVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGEHLLPYNMTVYQAVRQFSIQAEDERESTDDESNPLGRAGIWTK
THTIWYKPVREDEESNKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHDGVCPSVSNPLEVYLIPTPPENITFEDPSLDVILLLRVLHAIS
RYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNPEI
NQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLGLWRGEEVTLSNPKG
SQEGTKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHL
EDIVRQKKRLEQDKSQDLFGDDHNKNGFKMFDSSNYHGQDLLFKDATVRAVPVGEKTTYRGWLGLDYVAALEGMSSQQCSGAAAPAPGAP

--------------------------------------------------------------
>94244_94244_3_TRIP12-MFI2_TRIP12_chr2_230642030_ENST00000389045_MFI2_chr3_196730970_ENST00000296350_length(transcript)=6478nt_BP=4567nt
CCGGAGACTTTGGGGCCTAACTAGTGAATGGTAGTGTCTAGAAAGGGTATGTCCCTTCAAGAGAGAGGTGCCAATGTCCAACCGGCCTAA
TAACAATCCAGGGGGGTCACTGCGACGTTCACAGAGGAACACTGCCGGGGCCCAACCACAAGACGACTCAATAGGAGGAAGTCGGCGAGG
CTCTGGCCTGGGCAAAAGAGGAGCAGCTGAAGCTCGTCGACAGGAGAAAATGGCAGACCCTGAAAGCAACCAGGAGGCAGTAAATTCTTC
AGCTGCTCGGACAGATGAAGCTCCCCAAGGAGCTGCAGCCTCTAGTTCTGTTGCAGGGGCTGTTGGCATGACCACCTCTGGGGAGAGTGA
ATCAGATGATTCCGAGATGGGACGTTTGCAAGCTTTGTTAGAGGCAAGGGGTCTTCCCCCTCACCTATTTGGTCCTCTTGGTCCTCGGAT
GTCACAGCTTTTCCATAGAACAATTGGAAGTGGAGCTAGTTCTAAGGCCCAGCAGCTACTACAAGGATTGCAAGCCAGTGATGAAAGTCA
ACAGCTTCAGGCAGTTATTGAGATGTGTCAGTTACTGGTCATGGGAAATGAGGAGACACTGGGAGGGTTTCCTGTCAAGAGTGTTGTTCC
AGCTTTGATTACGTTACTTCAGATGGAGCACAATTTTGATATTATGAACCATGCTTGTCGAGCCTTAACATACATGATGGAAGCACTTCC
TCGATCTTCTGCTGTTGTAGTAGATGCTATTCCTGTCTTTTTAGAAAAGCTGCAAGTTATTCAGTGTATTGATGTGGCAGAGCAGGCCTT
GACTGCCTTGGAGATGTTGTCACGGAGACATAGTAAAGCCATTCTACAGGCGGGTGGTTTGGCAGACTGCTTGCTGTACCTAGAATTCTT
CAGCATAAATGCCCAAAGAAATGCATTAGCAATTGCAGCTAATTGCTGCCAGAGTATCACGCCAGATGAATTTCATTTTGTGGCAGATTC
ACTCCCATTGCTAACCCAAAGGCTAACACATCAGGATAAAAAGTCAGTAGAAAGCACTTGCCTTTGTTTTGCACGCCTAGTGGACAACTT
CCAGCATGAGGAGAATTTACTCCAGCAGGTTGCTTCCAAAGATCTGCTTACAAATGTTCAACAGCTGTTGGTAGTGACTCCACCCATTTT
AAGTTCTGGGATGTTTATAATGGTGGTTCGCATGTTTTCTCTGATGTGTTCCAACTGTCCAACTTTAGCTGTTCAACTTATGAAACAAAA
CATTGCAGAAACGCTTCACTTTCTCCTGTGTGGTGCCTCCAATGGAAGTTGTCAGGAACAGATTGATCTTGTTCCACGAAGCCCTCAAGA
GTTGTATGAACTGACATCTCTGATTTGTGAACTTATGCCATGTTTACCAAAAGAAGGCATTTTTGCAGTTGATACCATGTTGAAGAAGGG
AAATGCACAGAACACAGATGGTGCGATATGGCAGTGGCGTGATGATCGGGGCCTCTGGCATCCATATAACAGGATTGACAGCCGGATCAT
TGAGGCAGCCCATCAGGTCGGTGAGGATGAGATAAGCTTGTCCACTCTGGGACGAGTTTATACTATTGATTTTAATTCTATGCAGCAAAT
CAATGAGGACACGGGAACAGCACGTGCCATTCAGAGAAAACCTAACCCGTTAGCCAATAGTAACACTAGTGGATATTCAGAGTCAAAGAA
GGATGATGCTCGAGCACAGCTTATGAAAGAGGATCCGGAACTGGCTAAGTCTTTTATTAAGACATTATTTGGTGTTCTTTATGAAGTGTA
TAGTTCCTCAGCAGGACCTGCGGTCAGACATAAGTGCCTTAGAGCAATTCTTAGGATAATTTATTTTGCGGATGCTGAACTTCTGAAGGA
TGTTCTGAAAAATCATGCTGTTTCAAGTCACATTGCTTCCATGCTGTCAAGCCAAGACCTGAAGATAGTAGTGGGAGCACTTCAGATGGC
AGAAATTTTAATGCAGAAGTTACCTGATATTTTTAGTGTTTACTTCAGAAGAGAAGGTGTAATGCATCAAGTAAAACACTTAGCAGAATC
AGAGTCTTTGTTGACAAGTCCACCAAAGGCATGTACGAATGGATCGGGATCCATGGGATCCACAACTTCAGTCAGCAGTGGGACAGCCAC
AGCTGCCACTCATGCTGCAGCTGACTTGGGATCACCCAGCTTGCAGCACAGCAGGGATGATTCTTTAGATCTCAGCCCTCAAGGTCGATT
AAGTGATGTTCTAAAGAGAAAACGACTGCCAAAACGAGGGCCAAGAAGGCCAAAGTACTCACCTCCAAGAGATGATGACAAAGTAGACAA
TCAAGCTAAAAGCCCCACCACTACTCAGTCACCTAAATCTTCTTTCCTGGCAAGCTTGAATCCAAAAACATGGGGAAGGTTAAGTACACA
GTCCAACAGCAACAACATTGAGCCAGCACGGACTGCGGGAGGTAGTGGCCTTGCCAGGGCTGCCTCAAAGGATACCATCTCCAATAATAG
AGAAAAAATTAAAGGTTGGATTAAGGAGCAGGCACATAAATTTGTAGAACGTTATTTCAGTTCTGAGAATATGGATGGAAGCAACCCTGC
ATTGAATGTCCTTCAGAGACTTTGTGCTGCAACCGAACAACTCAACCTCCAGGTGGATGGTGGAGCTGAGTGCCTTGTAGAAATCCGTAG
CATAGTCTCAGAGTCAGATGTTTCATCATTTGAAATCCAACATAGTGGATTTGTGAAGCAGCTGTTGCTTTATTTGACATCTAAAAGTGA
AAAGGATGCTGTGAGCAGAGAGATCAGATTAAAGCGATTTCTTCATGTATTTTTTTCTTCTCCACTTCCTGGAGAAGAGCCCATTGGAAG
AGTGGAACCAGTGGGTAATGCACCTTTGTTGGCATTAGTTCACAAGATGAACAACTGCCTCAGCCAGATGGAACAATTTCCAGTCAAAGT
ACATGATTTCCCTAGTGGAAATGGGACAGGAGGCAGCTTTTCTCTCAACAGAGGATCACAGGCTTTAAAATTTTTCAACACACATCAATT
AAAATGCCAGTTACAAAGGCATCCAGACTGTGCAAATGTGAAGCAGTGGAAGGGTGGACCTGTCAAGATTGACCCTCTGGCTTTGGTACA
AGCCATCGAGAGATACCTTGTAGTTAGAGGGTATGGAAGAGTAAGAGAAGATGATGAAGACAGCGATGACGATGGATCAGATGAGGAAAT
AGATGAGTCTCTGGCTGCTCAGTTCCTAAATTCAGGAAATGTAAGACACAGGCTGCAGTTTTATATTGGAGAACATTTGCTGCCGTATAA
CATGACTGTGTATCAGGCAGTACGGCAGTTTAGTATACAGGCTGAAGATGAAAGAGAATCCACAGATGATGAGAGCAATCCTCTAGGCAG
AGCTGGTATTTGGACAAAGACTCATACAATATGGTATAAACCTGTGAGAGAGGATGAAGAAAGTAATAAAGATTGTGTTGGTGGTAAAAG
AGGAAGAGCCCAAACAGCTCCAACGAAAACTTCCCCTAGAAATGCAAAAAAGCATGATGAGTTATGGCACGATGGAGTGTGCCCATCAGT
ATCAAATCCTTTAGAAGTTTACCTCATTCCCACACCACCTGAAAATATAACATTTGAAGACCCGTCATTAGATGTGATCCTTCTTTTAAG
AGTTTTACATGCTATCAGTCGATACTGGTATTACTTGTATGATAATGCAATGTGCAAGGAAATTATTCCAACTAGTGAATTTATTAACAG
TAAGTTAACAGCAAAAGCAAATAGGCAACTTCAAGATCCTTTAGTAATCATGACAGGAAACATCCCAACATGGCTTACTGAGCTAGGAAA
AACCTGCCCATTTTTCTTTCCTTTTGATACCCGGCAAATGCTTTTTTATGTAACTGCATTTGATCGGGACCGAGCAATGCAAAGATTACT
TGATACCAACCCAGAAATCAACCAGTCTGATTCTCAAGATAGCAGAGTTGCACCTAGATTGGATAGAAAAAAACGTACTGTGAACCGAGA
GGAGCTGCTGAAACAGGCGGAGTCTGTGATGCAGGACCTCGGCAGCTCACGGGCCATGTTAGAAATCCAGTATGAAAATGAGGTTGGTAC
AGGTCTTGGGCCTACACTGGAGTTTTATGCGCTTGTATCTCAGGAACTACAGAGAGCTGACTTGGGTCTTTGGAGAGGTGAAGAAGTAAC
TCTTAGCAATCCAAAAGGGAGCCAAGAAGGGACCAAGTATATTCAAAACCTCCAGGGCCTGTTTGCGCTTCCCTTTGGTAGGACAGCAAA
GCCAGCTCATATCGCAAAGGTTAAGATGAAGTTTCGCTTCTTAGGAAAATTAATGGCCAAGGCTATCATGGATTTCAGATTGGTGGACCT
TCCCCTTGGCTTACCCTTTTATAAATGGATGCTACGGCAAGAAACTTCACTGACATCACACGATTTGTTTGACATCGACCCAGTTGTAGC
CAGATCAGTTTATCACCTAGAAGACATTGTCAGACAGAAGAAAAGACTTGAACAAGATAAATCCCAGGACCTGTTTGGAGACGACCACAA
TAAGAACGGGTTCAAAATGTTCGACTCCTCCAACTATCATGGCCAAGACCTGCTTTTCAAGGATGCCACCGTCCGGGCGGTGCCTGTCGG
AGAGAAAACCACCTACCGCGGCTGGCTGGGGCTGGACTACGTGGCGGCGCTGGAAGGGATGTCGTCTCAGCAGTGCTCGGGCGCAGCGGC
CCCGGCGCCCGGGGCGCCCCTGCTCCCGCTGCTGCTGCCCGCCCTCGCCGCCCGCCTGCTCCCGCCCGCCCTCTGAGCCCGGCCGCCCCG
CCCCAGAGCTCCGATGCCCGCCCGGGGAGTTTCCGCGGCGGCTTCGCGCTGGAATCCAGAAGGAAGCTCGCGAAGGCCGGGCCCGGCGTG
GGCGGGAGCAGGCGCCTCCCCGGGAGCCCCGCCGCCCACGGGCGCCACCTGGCGCTGCTACCTGAGGCGCCGCCCCCGGGCCCGCGCGGC
CCTTCCCGCCAACCGCCGCCTCCCGCCACCTGGAGCCGCGCGGGCCGCGCCGGAGGAGGCCGGTTGCCCAGGAAACCGCTGAGTCCGGGC
TTCCCGCCGCCCGCCCCGCGGTGTCGCCCGAGGGGCCCGCCCGCCTCCTCCCCGCAGCCCCGCGCCCCCGTCCGCGAGGCCCCCTGGGGA
CGCGGTGGCCGCCGAGGCGCCTACACCCGCAGGCCGCGGCCAGGCCGTCCCAGGAGGCCCCGGCGCCAACGGGACCCGGCGCGTGGGACA
GCGGCCTCTGCTGGCGGCGGCGGGAGGGAGGCCGGACCGGGGCGACGGGGAGAAGCCTTCGCCCGCGGGACCGTGTCCGGGGTGGGGGCT
CCAGTTCCTCCGACCGCCCGTGCGCTGGGAGGGAGGCCGAGCCCGGGGAACGCCGCGTGCCCTGCCTCGTCCCCCACTGTGGCCGCGCCA
GCTCCATCCCGGGCCAGCCGCGTCCACGGGCCCCCTCCCGAGTCTCCTCAGGCTCTCGCCTCCCCTACCCCCGTGGGATGCCCACCGCCC
GCACCCACGCCCGAGCCTGGCGGCAGCAGCCGCCCCCCGCCTGAAGGGAGCCGGAGGTGACCCAGGCCGCGGGCTCCCGAGGCCCCTGAA
GGGCTGCGCGTGGGGACCCGCCATGCTTCTGGGTTCCGAACGGGGGTGAGCTCCGTCTCCTCACCCGGCCCCGCACCCGCTGGGCCTGGG
GACCCCTCACTCCCCGTGCCCGCCCCTCCGCGAGGCAGCAGAAAGCGCCCGGCCGGGGCCTCTCTCTACTCCATCTTGCCACAGTTGTCT
GAGAAGCCAGAAAAAGTTTCCAGAACTGGCAGCCCTTAAAAAAAATGAAGAGGAAGAGAAGAAATGGGAGCAGGCAGCCCTCGTCAGCAG
ACCGGGAGCCGCGTGGGCGCGGAGCCATTTGCATTCCGGTCTGCGGGGGCTCGGGGATGCTGGTGACAGGCCCGGTTCCCGGTGGCTCGC
CCCCACCTGCGGGCGTCGGGAAGGATCCCTTCCATCTCTCAGCCGCAGAGGAGGCCCTGGCAGCGCCCCGGCTGTAGCCATGCAACCCCG
AGGAGTCCCGGGCACCTTCACCCCACCGGGAGGGGCCACAAGGACCTGGGCCTCGGCCACCAAGCTTTGTCCCCTCTCGCTGTGGGGGGC
TAGTGATTCTCCTCCGACCTGACGATTGCTTGGTTTTTTCAAAAGGGAGTTTTGTGCGGTGAGAAGTGTGTTTCTGTGTGGCTAACTCTG
GGCTAGCGTGCCGTGGCCATTGAAGGTGTGGCCTGCGTGGGTGCAGTGTAAGTGACGCTGGATTGTCAGGTGGCAGCAGGGGACCCCTGC

>94244_94244_3_TRIP12-MFI2_TRIP12_chr2_230642030_ENST00000389045_MFI2_chr3_196730970_ENST00000296350_length(amino acids)=1590AA_BP=1497
MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGSRRGSGLGKRGAAEARRQEKMADPESNQEAVNSSAARTDEAPQGAAASSSVAGAVGMT
TSGESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQASDESQQLQAVIEMCQLLVMGNEETLGGFP
VKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVDAIPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCL
LYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLV
VTPPILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCGASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVD
TMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIEAAHQVGEDEISLSTLGRVYTIDFNSMQQINEDTGTARAIQRKPNPLANSNTSG
YSESKKDDARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIASMLSSQDLKIVV
GALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAESESLLTSPPKACTNGSGSMGSTTSVSSGTATAATHAAADLGSPSLQHSRDDSLDL
SPQGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKSPTTTQSPKSSFLASLNPKTWGRLSTQSNSNNIEPARTAGGSGLARAASKD
TISNNREKIKGWIKEQAHKFVERYFSSENMDGSNPALNVLQRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLY
LTSKSEKDAVSREIRLKRFLHVFFSSPLPGEEPIGRVEPVGNAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGTGGSFSLNRGSQALKF
FNTHQLKCQLQRHPDCANVKQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGE
HLLPYNMTVYQAVRQFSIQAEDERESTDDESNPLGRAGIWTKTHTIWYKPVREDEESNKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHD
GVCPSVSNPLEVYLIPTPPENITFEDPSLDVILLLRVLHAISRYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTW
LTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNPEINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQY
ENEVGTGLGPTLEFYALVSQELQRADLGLWRGEEVTLSNPKGSQEGTKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMD
FRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQDLFGDDHNKNGFKMFDSSNYHGQDLLFKDATV

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for TRIP12-MFI2

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for TRIP12-MFI2

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for TRIP12-MFI2

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source