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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TRIT1-ADH1C (FusionGDB2 ID:94267)

Fusion Gene Summary for TRIT1-ADH1C

check button Fusion gene summary
Fusion gene informationFusion gene name: TRIT1-ADH1C
Fusion gene ID: 94267
HgeneTgene
Gene symbol

TRIT1

ADH1C

Gene ID

54802

126

Gene nametRNA isopentenyltransferase 1alcohol dehydrogenase 1C (class I), gamma polypeptide
SynonymsCOXPD35|GRO1|IPPT|IPT|IPTase|MOD5|hGRO1ADH3
Cytomap

1p34.2

4q23

Type of geneprotein-codingprotein-coding
DescriptiontRNA dimethylallyltransferaseIPP transferaseisopentenyl-diphosphate:tRNA isopentenyltransferasetRNA dimethylallyltransferase, mitochondrialtRNA isopentenylpyrophosphate transferasealcohol dehydrogenase 1CADH, gamma subunitalcohol dehydrogenase 3 (class I), gamma polypeptidealdehyde reductase
Modification date2020031320200313
UniProtAcc.

P00326

Ensembl transtripts involved in fusion geneENST00000316891, ENST00000372818, 
ENST00000441669, ENST00000544981, 
ENST00000491865, ENST00000537223, 
ENST00000537440, ENST00000541099, 
ENST00000545233, 		ENST00000510055, 
ENST00000515683, 
Fusion gene scores* DoF score7 X 2 X 4=563 X 4 X 2=24
# samples 63
** MAII scorelog2(6/56*10)=0.0995356735509144
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(3/24*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: TRIT1 [Title/Abstract] AND ADH1C [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTRIT1(40348990)-ADH1C(100268301), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneADH1C

GO:0006069

ethanol oxidation

6391957


check buttonFusion gene breakpoints across TRIT1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ADH1C (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-PD-A5DF-01ATRIT1chr1

40348990

-ADH1Cchr4

100268301

-
ChimerDB4LIHCTCGA-PD-A5DF-01ATRIT1chr1

40348990

-ADH1Cchr4

100269003

-


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Fusion Gene ORF analysis for TRIT1-ADH1C

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000316891ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
5CDS-5UTRENST00000316891ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
5CDS-5UTRENST00000372818ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
5CDS-5UTRENST00000372818ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
5CDS-5UTRENST00000441669ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
5CDS-5UTRENST00000441669ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
5CDS-5UTRENST00000544981ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
5CDS-5UTRENST00000544981ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
5UTR-3CDSENST00000491865ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
5UTR-3CDSENST00000491865ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
5UTR-3CDSENST00000537223ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
5UTR-3CDSENST00000537223ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
5UTR-3CDSENST00000537440ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
5UTR-3CDSENST00000537440ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
5UTR-3CDSENST00000541099ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
5UTR-3CDSENST00000541099ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
5UTR-3CDSENST00000545233ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
5UTR-3CDSENST00000545233ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
5UTR-5UTRENST00000491865ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
5UTR-5UTRENST00000491865ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
5UTR-5UTRENST00000537223ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
5UTR-5UTRENST00000537223ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
5UTR-5UTRENST00000537440ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
5UTR-5UTRENST00000537440ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
5UTR-5UTRENST00000541099ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
5UTR-5UTRENST00000541099ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
5UTR-5UTRENST00000545233ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
5UTR-5UTRENST00000545233ENST00000510055TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
In-frameENST00000316891ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
In-frameENST00000316891ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
In-frameENST00000372818ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
In-frameENST00000372818ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
In-frameENST00000441669ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
In-frameENST00000441669ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100269003

-
In-frameENST00000544981ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100268301

-
In-frameENST00000544981ENST00000515683TRIT1chr1

40348990

-ADH1Cchr4

100269003

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000441669TRIT1chr140348990-ENST00000515683ADH1Cchr4100268301-14421743901181263
ENST00000316891TRIT1chr140348990-ENST00000515683ADH1Cchr4100268301-14571894051196263
ENST00000372818TRIT1chr140348990-ENST00000515683ADH1Cchr4100268301-14571894051196263
ENST00000544981TRIT1chr140348990-ENST00000515683ADH1Cchr4100268301-14551874031194263
ENST00000441669TRIT1chr140348990-ENST00000515683ADH1Cchr4100269003-15441744921283263
ENST00000316891TRIT1chr140348990-ENST00000515683ADH1Cchr4100269003-15591895071298263
ENST00000372818TRIT1chr140348990-ENST00000515683ADH1Cchr4100269003-15591895071298263
ENST00000544981TRIT1chr140348990-ENST00000515683ADH1Cchr4100269003-15571875051296263

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000441669ENST00000515683TRIT1chr140348990-ADH1Cchr4100268301-0.0035103450.9964896
ENST00000316891ENST00000515683TRIT1chr140348990-ADH1Cchr4100268301-0.0043060170.9956939
ENST00000372818ENST00000515683TRIT1chr140348990-ADH1Cchr4100268301-0.0043060170.9956939
ENST00000544981ENST00000515683TRIT1chr140348990-ADH1Cchr4100268301-0.0037431150.9962568
ENST00000441669ENST00000515683TRIT1chr140348990-ADH1Cchr4100269003-0.0036974550.9963025
ENST00000316891ENST00000515683TRIT1chr140348990-ADH1Cchr4100269003-0.0040030490.99599695
ENST00000372818ENST00000515683TRIT1chr140348990-ADH1Cchr4100269003-0.0040030490.99599695
ENST00000544981ENST00000515683TRIT1chr140348990-ADH1Cchr4100269003-0.003332080.9966679

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Fusion Genomic Features for TRIT1-ADH1C


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TRIT1-ADH1C


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:40348990/chr4:100268301)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ADH1C

P00326

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRIT1chr1:40348990chr4:100268301ENST00000316891-11132_3758468.0RegionSubstrate binding
HgeneTRIT1chr1:40348990chr4:100268301ENST00000372818-11032_3758442.0RegionSubstrate binding
HgeneTRIT1chr1:40348990chr4:100268301ENST00000441669-1932_3758386.0RegionSubstrate binding
HgeneTRIT1chr1:40348990chr4:100269003ENST00000316891-11132_3758468.0RegionSubstrate binding
HgeneTRIT1chr1:40348990chr4:100269003ENST00000372818-11032_3758442.0RegionSubstrate binding
HgeneTRIT1chr1:40348990chr4:100269003ENST00000441669-1932_3758386.0RegionSubstrate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRIT1chr1:40348990chr4:100268301ENST00000316891-111395_42558468.0Zinc fingerNote=Matrin-type
HgeneTRIT1chr1:40348990chr4:100268301ENST00000372818-110395_42558442.0Zinc fingerNote=Matrin-type
HgeneTRIT1chr1:40348990chr4:100268301ENST00000441669-19395_42558386.0Zinc fingerNote=Matrin-type
HgeneTRIT1chr1:40348990chr4:100269003ENST00000316891-111395_42558468.0Zinc fingerNote=Matrin-type
HgeneTRIT1chr1:40348990chr4:100269003ENST00000372818-110395_42558442.0Zinc fingerNote=Matrin-type
HgeneTRIT1chr1:40348990chr4:100269003ENST00000441669-19395_42558386.0Zinc fingerNote=Matrin-type


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Fusion Gene Sequence for TRIT1-ADH1C


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>94267_94267_1_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000316891_ADH1C_chr4_100268301_ENST00000515683_length(transcript)=1457nt_BP=189nt
GCAGACTGCCATAAGATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTT
GTAGTGATTCTCGGGGCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGAC
TCCATGCAGATGGTGGCTGCAGGAATCTGTCGTTCAGATGAGCATGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCTGTGATTTTAGGC
CATGAGGCAGCCGGCATCGTGGAAAGTGTTTGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTCTTTACTCCTCAG
TGTGGAAAATGCAGAATTTGTAAAAACCCAGAAAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACCCTGCAGGATGGC
ACCAGGAGGTTCACCTGCAGCGGGAAGCCCATCCACCACTTCGTCGGCGTCAGCACCTTCTCCCAGTACACAGTGGTGGATGAGAATGCA
GTGGCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTTTCGACTGGTTATGGGTCTGCAGTCAAAGTT
GCCAAGGTCACCCCAGGGTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGTTGTTATGGGCTGTAAAGCAGCTGGAGCA
GCCAGAATCATTGCTGTGGACATCAACAAGGACAAATTTGCAAAGGCTAAAGAGTTGGGTGCCACTGAATGCATCAACCCTCAAGACTAC
AAGAAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTTGACACCATGATG
GCTTCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGTGTCATTGTAGGGGTACCTCCTGATTCCCAGAACCTCTCAATAAACCCTATG
CTGCTACTGACTGGACGCACGTGGAAAGGAGCTATTTTTGGAGGCTTTAAGAGTAAAGAATCTGTCCCCAAACTTGTGGCTGACTTTATG
GCTAAGAAGTTTTCACTGGATGCATTAATAACAAATATTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTTCGCTCTGGAAAG
AGTATCCGTACCGTCCTGACGTTTTGAAACAATACAGATGCCTTCCCTTGTAGCAGTTTTCAGCCTCCTCTACCCTACATGATCTGGAGC
AACAGCTAGGAAATATCATTAATTCTGCTCTTCAGAGATGTTAAAAATAAATTACACGTGGGAGCTTTCCAAAGAAATGGAAATTGATGG
GAAATTATTTGTCAAGCAAATGTTTAAAATCCAAATGAGAACTAAATAAAGTGTTGAACATCAACTGGGGAATTGAAGCCAATAAACCTT

>94267_94267_1_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000316891_ADH1C_chr4_100268301_ENST00000515683_length(amino acids)=263AA_BP=8
MKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLG
GVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVI

--------------------------------------------------------------
>94267_94267_2_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000316891_ADH1C_chr4_100269003_ENST00000515683_length(transcript)=1559nt_BP=189nt
GCAGACTGCCATAAGATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTT
GTAGTGATTCTCGGGGCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGAC
TCCATGCAGGTAATCAAATGCAAAGCAGCTGTGCTATGGGAGTTAAAGAAACCCTTTTCCATTGAGGAGGTAGAGGTTGCACCTCCTAAG
GCTCATGAAGTTCGCATTAAGATGGTGGCTGCAGGAATCTGTCGTTCAGATGAGCATGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCT
GTGATTTTAGGCCATGAGGCAGCCGGCATCGTGGAAAGTGTTTGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTC
TTTACTCCTCAGTGTGGAAAATGCAGAATTTGTAAAAACCCAGAAAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACC
CTGCAGGATGGCACCAGGAGGTTCACCTGCAGCGGGAAGCCCATCCACCACTTCGTCGGCGTCAGCACCTTCTCCCAGTACACAGTGGTG
GATGAGAATGCAGTGGCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTTTCGACTGGTTATGGGTCT
GCAGTCAAAGTTGCCAAGGTCACCCCAGGGTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGTTGTTATGGGCTGTAAA
GCAGCTGGAGCAGCCAGAATCATTGCTGTGGACATCAACAAGGACAAATTTGCAAAGGCTAAAGAGTTGGGTGCCACTGAATGCATCAAC
CCTCAAGACTACAAGAAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTT
GACACCATGATGGCTTCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGTGTCATTGTAGGGGTACCTCCTGATTCCCAGAACCTCTCA
ATAAACCCTATGCTGCTACTGACTGGACGCACGTGGAAAGGAGCTATTTTTGGAGGCTTTAAGAGTAAAGAATCTGTCCCCAAACTTGTG
GCTGACTTTATGGCTAAGAAGTTTTCACTGGATGCATTAATAACAAATATTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTT
CGCTCTGGAAAGAGTATCCGTACCGTCCTGACGTTTTGAAACAATACAGATGCCTTCCCTTGTAGCAGTTTTCAGCCTCCTCTACCCTAC
ATGATCTGGAGCAACAGCTAGGAAATATCATTAATTCTGCTCTTCAGAGATGTTAAAAATAAATTACACGTGGGAGCTTTCCAAAGAAAT
GGAAATTGATGGGAAATTATTTGTCAAGCAAATGTTTAAAATCCAAATGAGAACTAAATAAAGTGTTGAACATCAACTGGGGAATTGAAG

>94267_94267_2_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000316891_ADH1C_chr4_100269003_ENST00000515683_length(amino acids)=263AA_BP=8
MKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLG
GVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVI

--------------------------------------------------------------
>94267_94267_3_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000372818_ADH1C_chr4_100268301_ENST00000515683_length(transcript)=1457nt_BP=189nt
GCAGACTGCCATAAGATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTT
GTAGTGATTCTCGGGGCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGAC
TCCATGCAGATGGTGGCTGCAGGAATCTGTCGTTCAGATGAGCATGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCTGTGATTTTAGGC
CATGAGGCAGCCGGCATCGTGGAAAGTGTTTGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTCTTTACTCCTCAG
TGTGGAAAATGCAGAATTTGTAAAAACCCAGAAAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACCCTGCAGGATGGC
ACCAGGAGGTTCACCTGCAGCGGGAAGCCCATCCACCACTTCGTCGGCGTCAGCACCTTCTCCCAGTACACAGTGGTGGATGAGAATGCA
GTGGCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTTTCGACTGGTTATGGGTCTGCAGTCAAAGTT
GCCAAGGTCACCCCAGGGTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGTTGTTATGGGCTGTAAAGCAGCTGGAGCA
GCCAGAATCATTGCTGTGGACATCAACAAGGACAAATTTGCAAAGGCTAAAGAGTTGGGTGCCACTGAATGCATCAACCCTCAAGACTAC
AAGAAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTTGACACCATGATG
GCTTCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGTGTCATTGTAGGGGTACCTCCTGATTCCCAGAACCTCTCAATAAACCCTATG
CTGCTACTGACTGGACGCACGTGGAAAGGAGCTATTTTTGGAGGCTTTAAGAGTAAAGAATCTGTCCCCAAACTTGTGGCTGACTTTATG
GCTAAGAAGTTTTCACTGGATGCATTAATAACAAATATTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTTCGCTCTGGAAAG
AGTATCCGTACCGTCCTGACGTTTTGAAACAATACAGATGCCTTCCCTTGTAGCAGTTTTCAGCCTCCTCTACCCTACATGATCTGGAGC
AACAGCTAGGAAATATCATTAATTCTGCTCTTCAGAGATGTTAAAAATAAATTACACGTGGGAGCTTTCCAAAGAAATGGAAATTGATGG
GAAATTATTTGTCAAGCAAATGTTTAAAATCCAAATGAGAACTAAATAAAGTGTTGAACATCAACTGGGGAATTGAAGCCAATAAACCTT

>94267_94267_3_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000372818_ADH1C_chr4_100268301_ENST00000515683_length(amino acids)=263AA_BP=8
MKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLG
GVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVI

--------------------------------------------------------------
>94267_94267_4_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000372818_ADH1C_chr4_100269003_ENST00000515683_length(transcript)=1559nt_BP=189nt
GCAGACTGCCATAAGATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTT
GTAGTGATTCTCGGGGCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGAC
TCCATGCAGGTAATCAAATGCAAAGCAGCTGTGCTATGGGAGTTAAAGAAACCCTTTTCCATTGAGGAGGTAGAGGTTGCACCTCCTAAG
GCTCATGAAGTTCGCATTAAGATGGTGGCTGCAGGAATCTGTCGTTCAGATGAGCATGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCT
GTGATTTTAGGCCATGAGGCAGCCGGCATCGTGGAAAGTGTTTGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTC
TTTACTCCTCAGTGTGGAAAATGCAGAATTTGTAAAAACCCAGAAAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACC
CTGCAGGATGGCACCAGGAGGTTCACCTGCAGCGGGAAGCCCATCCACCACTTCGTCGGCGTCAGCACCTTCTCCCAGTACACAGTGGTG
GATGAGAATGCAGTGGCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTTTCGACTGGTTATGGGTCT
GCAGTCAAAGTTGCCAAGGTCACCCCAGGGTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGTTGTTATGGGCTGTAAA
GCAGCTGGAGCAGCCAGAATCATTGCTGTGGACATCAACAAGGACAAATTTGCAAAGGCTAAAGAGTTGGGTGCCACTGAATGCATCAAC
CCTCAAGACTACAAGAAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTT
GACACCATGATGGCTTCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGTGTCATTGTAGGGGTACCTCCTGATTCCCAGAACCTCTCA
ATAAACCCTATGCTGCTACTGACTGGACGCACGTGGAAAGGAGCTATTTTTGGAGGCTTTAAGAGTAAAGAATCTGTCCCCAAACTTGTG
GCTGACTTTATGGCTAAGAAGTTTTCACTGGATGCATTAATAACAAATATTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTT
CGCTCTGGAAAGAGTATCCGTACCGTCCTGACGTTTTGAAACAATACAGATGCCTTCCCTTGTAGCAGTTTTCAGCCTCCTCTACCCTAC
ATGATCTGGAGCAACAGCTAGGAAATATCATTAATTCTGCTCTTCAGAGATGTTAAAAATAAATTACACGTGGGAGCTTTCCAAAGAAAT
GGAAATTGATGGGAAATTATTTGTCAAGCAAATGTTTAAAATCCAAATGAGAACTAAATAAAGTGTTGAACATCAACTGGGGAATTGAAG

>94267_94267_4_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000372818_ADH1C_chr4_100269003_ENST00000515683_length(amino acids)=263AA_BP=8
MKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLG
GVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVI

--------------------------------------------------------------
>94267_94267_5_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000441669_ADH1C_chr4_100268301_ENST00000515683_length(transcript)=1442nt_BP=174nt
ATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGTAGTGATTCTCGGG
GCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGACTCCATGCAGATGGTG
GCTGCAGGAATCTGTCGTTCAGATGAGCATGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCTGTGATTTTAGGCCATGAGGCAGCCGGC
ATCGTGGAAAGTGTTTGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTCTTTACTCCTCAGTGTGGAAAATGCAGA
ATTTGTAAAAACCCAGAAAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACCCTGCAGGATGGCACCAGGAGGTTCACC
TGCAGCGGGAAGCCCATCCACCACTTCGTCGGCGTCAGCACCTTCTCCCAGTACACAGTGGTGGATGAGAATGCAGTGGCCAAAATTGAT
GCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTTTCGACTGGTTATGGGTCTGCAGTCAAAGTTGCCAAGGTCACCCCA
GGGTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGTTGTTATGGGCTGTAAAGCAGCTGGAGCAGCCAGAATCATTGCT
GTGGACATCAACAAGGACAAATTTGCAAAGGCTAAAGAGTTGGGTGCCACTGAATGCATCAACCCTCAAGACTACAAGAAACCCATTCAG
GAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTTGACACCATGATGGCTTCCCTGTTATGT
TGTCATGAGGCATGTGGCACAAGTGTCATTGTAGGGGTACCTCCTGATTCCCAGAACCTCTCAATAAACCCTATGCTGCTACTGACTGGA
CGCACGTGGAAAGGAGCTATTTTTGGAGGCTTTAAGAGTAAAGAATCTGTCCCCAAACTTGTGGCTGACTTTATGGCTAAGAAGTTTTCA
CTGGATGCATTAATAACAAATATTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTTCGCTCTGGAAAGAGTATCCGTACCGTC
CTGACGTTTTGAAACAATACAGATGCCTTCCCTTGTAGCAGTTTTCAGCCTCCTCTACCCTACATGATCTGGAGCAACAGCTAGGAAATA
TCATTAATTCTGCTCTTCAGAGATGTTAAAAATAAATTACACGTGGGAGCTTTCCAAAGAAATGGAAATTGATGGGAAATTATTTGTCAA
GCAAATGTTTAAAATCCAAATGAGAACTAAATAAAGTGTTGAACATCAACTGGGGAATTGAAGCCAATAAACCTTCCTTCTTAACCATTC

>94267_94267_5_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000441669_ADH1C_chr4_100268301_ENST00000515683_length(amino acids)=263AA_BP=8
MKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLG
GVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVI

--------------------------------------------------------------
>94267_94267_6_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000441669_ADH1C_chr4_100269003_ENST00000515683_length(transcript)=1544nt_BP=174nt
ATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGTAGTGATTCTCGGG
GCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGACTCCATGCAGGTAATC
AAATGCAAAGCAGCTGTGCTATGGGAGTTAAAGAAACCCTTTTCCATTGAGGAGGTAGAGGTTGCACCTCCTAAGGCTCATGAAGTTCGC
ATTAAGATGGTGGCTGCAGGAATCTGTCGTTCAGATGAGCATGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCTGTGATTTTAGGCCAT
GAGGCAGCCGGCATCGTGGAAAGTGTTTGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTCTTTACTCCTCAGTGT
GGAAAATGCAGAATTTGTAAAAACCCAGAAAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACCCTGCAGGATGGCACC
AGGAGGTTCACCTGCAGCGGGAAGCCCATCCACCACTTCGTCGGCGTCAGCACCTTCTCCCAGTACACAGTGGTGGATGAGAATGCAGTG
GCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTTTCGACTGGTTATGGGTCTGCAGTCAAAGTTGCC
AAGGTCACCCCAGGGTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGTTGTTATGGGCTGTAAAGCAGCTGGAGCAGCC
AGAATCATTGCTGTGGACATCAACAAGGACAAATTTGCAAAGGCTAAAGAGTTGGGTGCCACTGAATGCATCAACCCTCAAGACTACAAG
AAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTTGACACCATGATGGCT
TCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGTGTCATTGTAGGGGTACCTCCTGATTCCCAGAACCTCTCAATAAACCCTATGCTG
CTACTGACTGGACGCACGTGGAAAGGAGCTATTTTTGGAGGCTTTAAGAGTAAAGAATCTGTCCCCAAACTTGTGGCTGACTTTATGGCT
AAGAAGTTTTCACTGGATGCATTAATAACAAATATTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTTCGCTCTGGAAAGAGT
ATCCGTACCGTCCTGACGTTTTGAAACAATACAGATGCCTTCCCTTGTAGCAGTTTTCAGCCTCCTCTACCCTACATGATCTGGAGCAAC
AGCTAGGAAATATCATTAATTCTGCTCTTCAGAGATGTTAAAAATAAATTACACGTGGGAGCTTTCCAAAGAAATGGAAATTGATGGGAA
ATTATTTGTCAAGCAAATGTTTAAAATCCAAATGAGAACTAAATAAAGTGTTGAACATCAACTGGGGAATTGAAGCCAATAAACCTTCCT

>94267_94267_6_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000441669_ADH1C_chr4_100269003_ENST00000515683_length(amino acids)=263AA_BP=8
MKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLG
GVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVI

--------------------------------------------------------------
>94267_94267_7_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000544981_ADH1C_chr4_100268301_ENST00000515683_length(transcript)=1455nt_BP=187nt
AGACTGCCATAAGATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGT
AGTGATTCTCGGGGCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGACTC
CATGCAGATGGTGGCTGCAGGAATCTGTCGTTCAGATGAGCATGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCTGTGATTTTAGGCCA
TGAGGCAGCCGGCATCGTGGAAAGTGTTTGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTCTTTACTCCTCAGTG
TGGAAAATGCAGAATTTGTAAAAACCCAGAAAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACCCTGCAGGATGGCAC
CAGGAGGTTCACCTGCAGCGGGAAGCCCATCCACCACTTCGTCGGCGTCAGCACCTTCTCCCAGTACACAGTGGTGGATGAGAATGCAGT
GGCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTTTCGACTGGTTATGGGTCTGCAGTCAAAGTTGC
CAAGGTCACCCCAGGGTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGTTGTTATGGGCTGTAAAGCAGCTGGAGCAGC
CAGAATCATTGCTGTGGACATCAACAAGGACAAATTTGCAAAGGCTAAAGAGTTGGGTGCCACTGAATGCATCAACCCTCAAGACTACAA
GAAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTTGACACCATGATGGC
TTCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGTGTCATTGTAGGGGTACCTCCTGATTCCCAGAACCTCTCAATAAACCCTATGCT
GCTACTGACTGGACGCACGTGGAAAGGAGCTATTTTTGGAGGCTTTAAGAGTAAAGAATCTGTCCCCAAACTTGTGGCTGACTTTATGGC
TAAGAAGTTTTCACTGGATGCATTAATAACAAATATTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTTCGCTCTGGAAAGAG
TATCCGTACCGTCCTGACGTTTTGAAACAATACAGATGCCTTCCCTTGTAGCAGTTTTCAGCCTCCTCTACCCTACATGATCTGGAGCAA
CAGCTAGGAAATATCATTAATTCTGCTCTTCAGAGATGTTAAAAATAAATTACACGTGGGAGCTTTCCAAAGAAATGGAAATTGATGGGA
AATTATTTGTCAAGCAAATGTTTAAAATCCAAATGAGAACTAAATAAAGTGTTGAACATCAACTGGGGAATTGAAGCCAATAAACCTTCC

>94267_94267_7_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000544981_ADH1C_chr4_100268301_ENST00000515683_length(amino acids)=263AA_BP=8
MKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLG
GVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVI

--------------------------------------------------------------
>94267_94267_8_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000544981_ADH1C_chr4_100269003_ENST00000515683_length(transcript)=1557nt_BP=187nt
AGACTGCCATAAGATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGT
AGTGATTCTCGGGGCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGACTC
CATGCAGGTAATCAAATGCAAAGCAGCTGTGCTATGGGAGTTAAAGAAACCCTTTTCCATTGAGGAGGTAGAGGTTGCACCTCCTAAGGC
TCATGAAGTTCGCATTAAGATGGTGGCTGCAGGAATCTGTCGTTCAGATGAGCATGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCTGT
GATTTTAGGCCATGAGGCAGCCGGCATCGTGGAAAGTGTTTGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTCTT
TACTCCTCAGTGTGGAAAATGCAGAATTTGTAAAAACCCAGAAAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACCCT
GCAGGATGGCACCAGGAGGTTCACCTGCAGCGGGAAGCCCATCCACCACTTCGTCGGCGTCAGCACCTTCTCCCAGTACACAGTGGTGGA
TGAGAATGCAGTGGCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTTTCGACTGGTTATGGGTCTGC
AGTCAAAGTTGCCAAGGTCACCCCAGGGTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGTTGTTATGGGCTGTAAAGC
AGCTGGAGCAGCCAGAATCATTGCTGTGGACATCAACAAGGACAAATTTGCAAAGGCTAAAGAGTTGGGTGCCACTGAATGCATCAACCC
TCAAGACTACAAGAAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTTGA
CACCATGATGGCTTCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGTGTCATTGTAGGGGTACCTCCTGATTCCCAGAACCTCTCAAT
AAACCCTATGCTGCTACTGACTGGACGCACGTGGAAAGGAGCTATTTTTGGAGGCTTTAAGAGTAAAGAATCTGTCCCCAAACTTGTGGC
TGACTTTATGGCTAAGAAGTTTTCACTGGATGCATTAATAACAAATATTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTTCG
CTCTGGAAAGAGTATCCGTACCGTCCTGACGTTTTGAAACAATACAGATGCCTTCCCTTGTAGCAGTTTTCAGCCTCCTCTACCCTACAT
GATCTGGAGCAACAGCTAGGAAATATCATTAATTCTGCTCTTCAGAGATGTTAAAAATAAATTACACGTGGGAGCTTTCCAAAGAAATGG
AAATTGATGGGAAATTATTTGTCAAGCAAATGTTTAAAATCCAAATGAGAACTAAATAAAGTGTTGAACATCAACTGGGGAATTGAAGCC

>94267_94267_8_TRIT1-ADH1C_TRIT1_chr1_40348990_ENST00000544981_ADH1C_chr4_100269003_ENST00000515683_length(amino acids)=263AA_BP=8
MKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLG
GVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TRIT1-ADH1C


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneTRIT1chr1:40348990chr4:100268301ENST00000316891-11155_5858.0468.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100268301ENST00000372818-11055_5858.0442.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100268301ENST00000441669-1955_5858.0386.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100269003ENST00000316891-11155_5858.0468.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100269003ENST00000372818-11055_5858.0442.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100269003ENST00000441669-1955_5858.0386.0substrate tRNA


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneTRIT1chr1:40348990chr4:100268301ENST00000316891-111233_25558.0468.0isopentenylpyrophosphate transferase
HgeneTRIT1chr1:40348990chr4:100268301ENST00000372818-110233_25558.0442.0isopentenylpyrophosphate transferase
HgeneTRIT1chr1:40348990chr4:100268301ENST00000441669-19233_25558.0386.0isopentenylpyrophosphate transferase
HgeneTRIT1chr1:40348990chr4:100269003ENST00000316891-111233_25558.0468.0isopentenylpyrophosphate transferase
HgeneTRIT1chr1:40348990chr4:100269003ENST00000372818-110233_25558.0442.0isopentenylpyrophosphate transferase
HgeneTRIT1chr1:40348990chr4:100269003ENST00000441669-19233_25558.0386.0isopentenylpyrophosphate transferase
HgeneTRIT1chr1:40348990chr4:100268301ENST00000316891-111183_18758.0468.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100268301ENST00000316891-111281_28358.0468.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100268301ENST00000316891-111313_33158.0468.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100268301ENST00000316891-111323_33058.0468.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100268301ENST00000372818-110183_18758.0442.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100268301ENST00000372818-110281_28358.0442.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100268301ENST00000372818-110313_33158.0442.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100268301ENST00000372818-110323_33058.0442.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100268301ENST00000441669-19183_18758.0386.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100268301ENST00000441669-19281_28358.0386.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100268301ENST00000441669-19313_33158.0386.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100268301ENST00000441669-19323_33058.0386.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100269003ENST00000316891-111183_18758.0468.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100269003ENST00000316891-111281_28358.0468.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100269003ENST00000316891-111313_33158.0468.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100269003ENST00000316891-111323_33058.0468.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100269003ENST00000372818-110183_18758.0442.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100269003ENST00000372818-110281_28358.0442.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100269003ENST00000372818-110313_33158.0442.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100269003ENST00000372818-110323_33058.0442.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100269003ENST00000441669-19183_18758.0386.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100269003ENST00000441669-19281_28358.0386.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100269003ENST00000441669-19313_33158.0386.0substrate tRNA
HgeneTRIT1chr1:40348990chr4:100269003ENST00000441669-19323_33058.0386.0substrate tRNA


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TRIT1-ADH1C


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TRIT1-ADH1C


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource