FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:TRMT10B-AR (FusionGDB2 ID:94274)

Fusion Gene Summary for TRMT10B-AR

check button Fusion gene summary
Fusion gene informationFusion gene name: TRMT10B-AR
Fusion gene ID: 94274
HgeneTgene
Gene symbol

TRMT10B

AR

Gene ID

158234

374

Gene nametRNA methyltransferase 10Bamphiregulin
SynonymsRG9MTD3|bA3J10.9AR|AREGB|CRDGF|SDGF
Cytomap

9p13.2

4q13.3

Type of geneprotein-codingprotein-coding
DescriptiontRNA methyltransferase 10 homolog BRNA (guanine-9-) methyltransferase domain containing 3RNA (guanine-9-)-methyltransferase domain-containing protein 3tRNA (guanine(9)-N(1))-methyltransferase TRMT10Bamphiregulinamphiregulin Bcolorectum cell-derived growth factorschwannoma-derived growth factor
Modification date2020031320200327
UniProtAcc.

ARSK

Ensembl transtripts involved in fusion geneENST00000297994, ENST00000377753, 
ENST00000377754, ENST00000537911, 
ENST00000396043, ENST00000396044, 
ENST00000504326, ENST00000513847, 
ENST00000374690, 
Fusion gene scores* DoF score2 X 3 X 2=1214 X 10 X 11=1540
# samples 316
** MAII scorelog2(3/12*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(16/1540*10)=-3.2667865406949
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TRMT10B [Title/Abstract] AND AR [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTRMT10B(37776402)-AR(66905852), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneAR

GO:0007173

epidermal growth factor receptor signaling pathway

12743035

TgeneAR

GO:0007186

G protein-coupled receptor signaling pathway

12743035


check buttonFusion gene breakpoints across TRMT10B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across AR (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A08I-01ATRMT10Bchr9

37776402

+ARchrX

66905852

+


Top

Fusion Gene ORF analysis for TRMT10B-AR

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000297994ENST00000396043TRMT10Bchr9

37776402

+ARchrX

66905852

+
5CDS-3UTRENST00000297994ENST00000396044TRMT10Bchr9

37776402

+ARchrX

66905852

+
5CDS-3UTRENST00000297994ENST00000504326TRMT10Bchr9

37776402

+ARchrX

66905852

+
5CDS-3UTRENST00000297994ENST00000513847TRMT10Bchr9

37776402

+ARchrX

66905852

+
5CDS-3UTRENST00000377753ENST00000396043TRMT10Bchr9

37776402

+ARchrX

66905852

+
5CDS-3UTRENST00000377753ENST00000396044TRMT10Bchr9

37776402

+ARchrX

66905852

+
5CDS-3UTRENST00000377753ENST00000504326TRMT10Bchr9

37776402

+ARchrX

66905852

+
5CDS-3UTRENST00000377753ENST00000513847TRMT10Bchr9

37776402

+ARchrX

66905852

+
5CDS-3UTRENST00000377754ENST00000396043TRMT10Bchr9

37776402

+ARchrX

66905852

+
5CDS-3UTRENST00000377754ENST00000396044TRMT10Bchr9

37776402

+ARchrX

66905852

+
5CDS-3UTRENST00000377754ENST00000504326TRMT10Bchr9

37776402

+ARchrX

66905852

+
5CDS-3UTRENST00000377754ENST00000513847TRMT10Bchr9

37776402

+ARchrX

66905852

+
5CDS-3UTRENST00000537911ENST00000396043TRMT10Bchr9

37776402

+ARchrX

66905852

+
5CDS-3UTRENST00000537911ENST00000396044TRMT10Bchr9

37776402

+ARchrX

66905852

+
5CDS-3UTRENST00000537911ENST00000504326TRMT10Bchr9

37776402

+ARchrX

66905852

+
5CDS-3UTRENST00000537911ENST00000513847TRMT10Bchr9

37776402

+ARchrX

66905852

+
In-frameENST00000297994ENST00000374690TRMT10Bchr9

37776402

+ARchrX

66905852

+
In-frameENST00000377753ENST00000374690TRMT10Bchr9

37776402

+ARchrX

66905852

+
In-frameENST00000377754ENST00000374690TRMT10Bchr9

37776402

+ARchrX

66905852

+
In-frameENST00000537911ENST00000374690TRMT10Bchr9

37776402

+ARchrX

66905852

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000377753TRMT10Bchr937776402+ENST00000374690ARchrX66905852+8458685751679534
ENST00000537911TRMT10Bchr937776402+ENST00000374690ARchrX66905852+8533760691754561
ENST00000377754TRMT10Bchr937776402+ENST00000374690ARchrX66905852+85738002411794517
ENST00000297994TRMT10Bchr937776402+ENST00000374690ARchrX66905852+8682909651903612

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000377753ENST00000374690TRMT10Bchr937776402+ARchrX66905852+0.0003305410.99966943
ENST00000537911ENST00000374690TRMT10Bchr937776402+ARchrX66905852+0.0002659690.999734
ENST00000377754ENST00000374690TRMT10Bchr937776402+ARchrX66905852+0.0005614490.9994386
ENST00000297994ENST00000374690TRMT10Bchr937776402+ARchrX66905852+0.0002570720.9997429

Top

Fusion Genomic Features for TRMT10B-AR


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TRMT10Bchr937776402+ARchrX66905851+2.33E-050.99997663
TRMT10Bchr937776402+ARchrX66905851+2.33E-050.99997663

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for TRMT10B-AR


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:37776402/chrX:66905852)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AR

ARSK

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.536

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRMT10Bchr9:37776402chrX:66905852ENST00000297994+8973_97281317.0Coiled coilOntology_term=ECO:0000255
HgeneTRMT10Bchr9:37776402chrX:66905852ENST00000377754+7873_97186222.0Coiled coilOntology_term=ECO:0000255
TgeneARchr9:37776402chrX:66905852ENST0000039604318195_19957389.0Compositional biasNote=Poly-Gln
TgeneARchr9:37776402chrX:66905852ENST0000039604318374_38357389.0Compositional biasNote=Poly-Pro
TgeneARchr9:37776402chrX:66905852ENST0000039604318398_40457389.0Compositional biasNote=Poly-Ala
TgeneARchr9:37776402chrX:66905852ENST0000039604318451_47357389.0Compositional biasNote=Poly-Gly
TgeneARchr9:37776402chrX:66905852ENST000003960431858_12057389.0Compositional biasNote=Gln-rich
TgeneARchr9:37776402chrX:66905852ENST000003960431858_8057389.0Compositional biasNote=Poly-Gln
TgeneARchr9:37776402chrX:66905852ENST000003960431886_9157389.0Compositional biasNote=Poly-Gln
TgeneARchr9:37776402chrX:66905852ENST0000039604318560_63257389.0DNA bindingNuclear receptor
TgeneARchr9:37776402chrX:66905852ENST0000039604318669_90057389.0DomainNR LBD
TgeneARchr9:37776402chrX:66905852ENST0000039604318560_58057389.0Zinc fingerNR C4-type
TgeneARchr9:37776402chrX:66905852ENST0000039604318596_62057389.0Zinc fingerNR C4-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRMT10Bchr9:37776402chrX:66905852ENST00000297994+89113_310281317.0DomainSAM-dependent MTase TRM10-type
HgeneTRMT10Bchr9:37776402chrX:66905852ENST00000377754+78113_310186222.0DomainSAM-dependent MTase TRM10-type
TgeneARchr9:37776402chrX:66905852ENST00000396043181_55957389.0RegionNote=Modulating


Top

Fusion Gene Sequence for TRMT10B-AR


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>94274_94274_1_TRMT10B-AR_TRMT10B_chr9_37776402_ENST00000297994_AR_chrX_66905852_ENST00000374690_length(transcript)=8682nt_BP=909nt
CGCGCCGCTGCCGCTGCGTGGGGGTGAGGGGATCAGTCTGGTGGAAAGGACAGAGGACTAAGTCCATGGACTGGAAATTGGAAGGGAGTA
CTCAGAAAGTAGAGTCACCTGTGCTGCAGGGGCAAGAAGGCATCCTAGAGGAGACAGGTGAAGATGGACTTCCTGAAGGCTTCCAGCTTC
TGCAGATCGATGCGGAAGGCGAGTGCCAGGAGGGAGAGATCCTGGCCACAGGCAGTACGGCATGGTGCTCGAAAAATGTCCAGAGAAAAC
AGAGACACTGGGAAAAGATAGTTGCAGCAAAGAAGAGCAAAAGAAAGCAAGAAAAAGAACGAAGAAAAGCCAATCGTGCAGAAAATCCAG
GCATTTGCCCCCAGCACAGCAAACGTTTCCTGAGAGCTCTAACCAAAGACAAACTTTTGGAAGCCAAACACTCAGGACCAAGACTATGTA
TCGATTTGAGTATGACCCACTACATGTCAAAGAAGGAATTAAGTAGACTGGCTGGACAGATTCGAAGGTTGTATGGTTCAAACAAAAAAG
CTGACAGGCCATTTTGGATCTGCCTCACTGGATTCACAACAGACAGTCCCCTTTATGAAGAGTGTGTGAGGATGAATGATGGATTTTCTA
GTTACCTGTTAGACATAACAGAAGAAGACTGCTTTAGTTTATTTCCCTTGGAAACCCTTGTGTACCTGACTCCTGACTCAGAACACGCTC
TTGAAGATGTTGATCTAAACAAAGTTTACATCCTCGGTGGGCTTGTGGATGAAAGCATTCAGAAGAAGGTGACATTTCAAAAGGCCCGGG
AATACTCTGTCAAGACCGCACGCTTGCCAATCCAGGAATACATGGTCAGAAACCAGAATGGGAAAAACTATCATTCAGAGATACTGGCCA
TCAATCAAGGGAAACAGAAGTACCTGTGCGCCAGCAGAAATGATTGCACTATTGATAAATTCCGAAGGAAAAATTGTCCATCTTGTCGTC
TTCGGAAATGTTATGAAGCAGGGATGACTCTGGGAGCCCGGAAGCTGAAGAAACTTGGTAATCTGAAACTACAGGAGGAAGGAGAGGCTT
CCAGCACCACCAGCCCCACTGAGGAGACAACCCAGAAGCTGACAGTGTCACACATTGAAGGCTATGAATGTCAGCCCATCTTTCTGAATG
TCCTGGAAGCCATTGAGCCAGGTGTAGTGTGTGCTGGACACGACAACAACCAGCCCGACTCCTTTGCAGCCTTGCTCTCTAGCCTCAATG
AACTGGGAGAGAGACAGCTTGTACACGTGGTCAAGTGGGCCAAGGCCTTGCCTGGCTTCCGCAACTTACACGTGGACGACCAGATGGCTG
TCATTCAGTACTCCTGGATGGGGCTCATGGTGTTTGCCATGGGCTGGCGATCCTTCACCAATGTCAACTCCAGGATGCTCTACTTCGCCC
CTGATCTGGTTTTCAATGAGTACCGCATGCACAAGTCCCGGATGTACAGCCAGTGTGTCCGAATGAGGCACCTCTCTCAAGAGTTTGGAT
GGCTCCAAATCACCCCCCAGGAATTCCTGTGCATGAAAGCACTGCTACTCTTCAGCATTATTCCAGTGGATGGGCTGAAAAATCAAAAAT
TCTTTGATGAACTTCGAATGAACTACATCAAGGAACTCGATCGTATCATTGCATGCAAAAGAAAAAATCCCACATCCTGCTCAAGACGCT
TCTACCAGCTCACCAAGCTCCTGGACTCCGTGCAGCCTATTGCGAGAGAGCTGCATCAGTTCACTTTTGACCTGCTAATCAAGTCACACA
TGGTGAGCGTGGACTTTCCGGAAATGATGGCAGAGATCATCTCTGTGCAAGTGCCCAAGATCCTTTCTGGGAAAGTCAAGCCCATCTATT
TCCACACCCAGTGAAGCATTGGAAACCCTATTTCCCCACCCCAGCTCATGCCCCCTTTCAGATGTCTTCTGCCTGTTATAACTCTGCACT
ACTCCTCTGCAGTGCCTTGGGGAATTTCCTCTATTGATGTACAGTCTGTCATGAACATGTTCCTGAATTCTATTTGCTGGGCTTTTTTTT
TCTCTTTCTCTCCTTTCTTTTTCTTCTTCCCTCCCTATCTAACCCTCCCATGGCACCTTCAGACTTTGCTTCCCATTGTGGCTCCTATCT
GTGTTTTGAATGGTGTTGTATGCCTTTAAATCTGTGATGATCCTCATATGGCCCAGTGTCAAGTTGTGCTTGTTTACAGCACTACTCTGT
GCCAGCCACACAAACGTTTACTTATCTTATGCCACGGGAAGTTTAGAGAGCTAAGATTATCTGGGGAAATCAAAACAAAAACAAGCAAAC
AAAAAAAAAAAGCAAAAACAAAACAAAAAATAAGCCAAAAAACCTTGCTAGTGTTTTTTCCTCAAAAATAAATAAATAAATAAATAAATA
CGTACATACATACACACATACATACAAACATATAGAAATCCCCAAAGAGGCCAATAGTGACGAGAAGGTGAAAATTGCAGGCCCATGGGG
AGTTACTGATTTTTTCATCTCCTCCCTCCACGGGAGACTTTATTTTCTGCCAATGGCTATTGCCATTAGAGGGCAGAGTGACCCCAGAGC
TGAGTTGGGCAGGGGGGTGGACAGAGAGGAGAGGACAAGGAGGGCAATGGAGCATCAGTACCTGCCCACAGCCTTGGTCCCTGGGGGCTA
GACTGCTCAACTGTGGAGCAATTCATTATACTGAAAATGTGCTTGTTGTTGAAAATTTGTCTGCATGTTAATGCCTCACCCCCAAACCCT
TTTCTCTCTCACTCTCTGCCTCCAACTTCAGATTGACTTTCAATAGTTTTTCTAAGACCTTTGAACTGAATGTTCTCTTCAGCCAAAACT
TGGCGACTTCCACAGAAAAGTCTGACCACTGAGAAGAAGGAGAGCAGAGATTTAACCCTTTGTAAGGCCCCATTTGGATCCAGGTCTGCT
TTCTCATGTGTGAGTCAGGGAGGAGCTGGAGCCAGAGGAGAAGAAAATGATAGCTTGGCTGTTCTCCTGCTTAGGACACTGACTGAATAG
TTAAACTCTCACTGCCACTACCTTTTCCCCACCTTTAAAAGACCTGAATGAAGTTTTCTGCCAAACTCCGTGAAGCCACAAGCACCTTAT
GTCCTCCCTTCAGTGTTTTGTGGGCCTGAATTTCATCACACTGCATTTCAGCCATGGTCATCAAGCCTGTTTGCTTCTTTTGGGCATGTT
CACAGATTCTCTGTTAAGAGCCCCCACCACCAAGAAGGTTAGCAGGCCAACAGCTCTGACATCTATCTGTAGATGCCAGTAGTCACAAAG
ATTTCTTACCAACTCTCAGATCGCTGGAGCCCTTAGACAAACTGGAAAGAAGGCATCAAAGGGATCAGGCAAGCTGGGCGTCTTGCCCTT
GTCCCCCAGAGATGATACCCTCCCAGCAAGTGGAGAAGTTCTCACTTCCTTCTTTAGAGCAGCTAAAGGGGCTACCCAGATCAGGGTTGA
AGAGAAAACTCAATTACCAGGGTGGGAAGAATGAAGGCACTAGAACCAGAAACCCTGCAAATGCTCTTCTTGTCACCCAGCATATCCACC
TGCAGAAGTCATGAGAAGAGAGAAGGAACAAAGAGGAGACTCTGACTACTGAATTAAAATCTTCAGCGGCAAAGCCTAAAGCCAGATGGA
CACCATCTGGTGAGTTTACTCATCATCCTCCTCTGCTGCTGATTCTGGGCTCTGACATTGCCCATACTCACTCAGATTCCCCACCTTTGT
TGCTGCCTCTTAGTCAGAGGGAGGCCAAACCATTGAGACTTTCTACAGAACCATGGCTTCTTTCGGAAAGGTCTGGTTGGTGTGGCTCCA
ATACTTTGCCACCCATGAACTCAGGGTGTGCCCTGGGACACTGGTTTTATATAGTCTTTTGGCACACCTGTGTTCTGTTGACTTCGTTCT
TCAAGCCCAAGTGCAAGGGAAAATGTCCACCTACTTTCTCATCTTGGCCTCTGCCTCCTTACTTAGCTCTTAATCTCATCTGTTGAACTC
AAGAAATCAAGGGCCAGTCATCAAGCTGCCCATTTTAATTGATTCACTCTGTTTGTTGAGAGGATAGTTTCTGAGTGACATGATATGATC
CACAAGGGTTTCCTTCCCTGATTTCTGCATTGATATTAATAGCCAAACGAACTTCAAAACAGCTTTAAATAACAAGGGAGAGGGGAACCT
AAGATGAGTAATATGCCAATCCAAGACTGCTGGAGAAAACTAAAGCTGACAGGTTCCCTTTTTGGGGTGGGATAGACATGTTCTGGTTTT
CTTTATTATTACACAATCTGGCTCATGTACAGGATCACTTTTAGCTGTTTTAAACAGAAAAAAATATCCACCACTCTTTTCAGTTACACT
AGGTTACATTTTAATAGGTCCTTTACATCTGTTTTGGAATGATTTTCATCTTTTGTGATACACAGATTGAATTATATCATTTTCATATCT
CTCCTTGTAAATACTAGAAGCTCTCCTTTACATTTCTCTATCAAATTTTTCATCTTTATGGGTTTCCCAATTGTGACTCTTGTCTTCATG
AATATATGTTTTTCATTTGCAAAAGCCAAAAATCAGTGAAACAGCAGTGTAATTAAAAGCAACAACTGGATTACTCCAAATTTCCAAATG
ACAAAACTAGGGAAAAATAGCCTACACAAGCCTTTAGGCCTACTCTTTCTGTGCTTGGGTTTGAGTGAACAAAGGAGATTTTAGCTTGGC
TCTGTTCTCCCATGGATGAAAGGAGGAGGATTTTTTTTTTCTTTTGGCCATTGATGTTCTAGCCAATGTAATTGACAGAAGTCTCATTTT
GCATGCGCTCTGCTCTACAAACAGAGTTGGTATGGTTGGTATACTGTACTCACCTGTGAGGGACTGGCCACTCAGACCCACTTAGCTGGT
GAGCTAGAAGATGAGGATCACTCACTGGAAAAGTCACAAGGACCATCTCCAAACAAGTTGGCAGTGCTCGATGTGGACGAAGAGTGAGGA
AGAGAAAAAGAAGGAGCACCAGGGAGAAGGCTCCGTCTGTGCTGGGCAGCAGACAGCTGCCAGGATCACGAACTCTGTAGTCAAAGAAAA
GAGTCGTGTGGCAGTTTCAGCTCTCGTTCATTGGGCAGCTCGCCTAGGCCCAGCCTCTGAGCTGACATGGGAGTTGTTGGATTCTTTGTT
TCATAGCTTTTTCTATGCCATAGGCAATATTGTTGTTCTTGGAAAGTTTATTATTTTTTTAACTCCCTTACTCTGAGAAAGGGATATTTT
GAAGGACTGTCATATATCTTTGAAAAAAGAAAATCTGTAATACATATATTTTTATGTATGTTCACTGGCACTAAAAAATATAGAGAGCTT
CATTCTGTCCTTTGGGTAGTTGCTGAGGTAATTGTCCAGGTTGAAAAATAATGTGCTGATGCTAGAGTCCCTCTCTGTCCATACTCTACT
TCTAAATACATATAGGCATACATAGCAAGTTTTATTTGACTTGTACTTTAAGAGAAAATATGTCCACCATCCACATGATGCACAAATGAG
CTAACATTGAGCTTCAAGTAGCTTCTAAGTGTTTGTTTCATTAGGCACAGCACAGATGTGGCCTTTCCCCCCTTCTCTCCCTTGATATCT
GGCAGGGCATAAAGGCCCAGGCCACTTCCTCTGCCCCTTCCCAGCCCTGCACCAAAGCTGCATTTCAGGAGACTCTCTCCAGACAGCCCA
GTAACTACCCGAGCATGGCCCCTGCATAGCCCTGGAAAAATAAGAGGCTGACTGTCTACGAATTATCTTGTGCCAGTTGCCCAGGTGAGA
GGGCACTGGGCCAAGGGAGTGGTTTTCATGTTTGACCCACTACAAGGGGTCATGGGAATCAGGAATGCCAAAGCACCAGATCAAATCCAA
AACTTAAAGTCAAAATAAGCCATTCAGCATGTTCAGTTTCTTGGAAAAGGAAGTTTCTACCCCTGATGCCTTTGTAGGCAGATCTGTTCT
CACCATTAATCTTTTTGAAAATCTTTTAAAGCAGTTTTTAAAAAGAGAGATGAAAGCATCACATTATATAACCAAAGATTACATTGTACC
TGCTAAGATACCAAAATTCATAAGGGCAGGGGGGGAGCAAGCATTAGTGCCTCTTTGATAAGCTGTCCAAAGACAGACTAAAGGACTCTG
CTGGTGACTGACTTATAAGAGCTTTGTGGGTTTTTTTTTCCCTAATAATATACATGTTTAGAAGAATTGAAAATAATTTCGGGAAAATGG
GATTATGGGTCCTTCACTAAGTGATTTTATAAGCAGAACTGGCTTTCCTTTTCTCTAGTAGTTGCTGAGCAAATTGTTGAAGCTCCATCA
TTGCATGGTTGGAAATGGAGCTGTTCTTAGCCACTGTGTTTGCTAGTGCCCATGTTAGCTTATCTGAAGATGTGAAACCCTTGCTGATAA
GGGAGCATTTAAAGTACTAGATTTTGCACTAGAGGGACAGCAGGCAGAAATCCTTATTTCTGCCCACTTTGGATGGCACAAAAAGTTATC
TGCAGTTGAAGGCAGAAAGTTGAAATACATTGTAAATGAATATTTGTATCCATGTTTCAAAATTGAAATATATATATATATATATATATA
TATATATATATATATATAGTGTGTGTGTGTGTTCTGATAGCTTTAACTTTCTCTGCATCTTTATATTTGGTTCCAGATCACACCTGATGC
CATGTACTTGTGAGAGAGGATGCAGTTTTGTTTTGGAAGCTCTCTCAGAACAAACAAGACACCTGGATTGATCAGTTAACTAAAAGTTTT
CTCCCCTATTGGGTTTGACCCACAGGTCCTGTGAAGGAGCAGAGGGATAAAAAGAGTAGAGGACATGATACATTGTACTTTACTAGTTCA
AGACAGATGAATGTGGAAAGCATAAAAACTCAATGGAACTGACTGAGATTTACCACAGGGAAGGCCCAAACTTGGGGCCAAAAGCCTACC
CAAGTGATTGACCAGTGGCCCCCTAATGGGACCTGAGCTGTTGGAAGAAGAGAACTGTTCCTTGGTCTTCACCATCCTTGTGAGAGAAGG
GCAGTTTCCTGCATTGGAACCTGGAGCAAGCGCTCTATCTTTCACACAAATTCCCTCACCTGAGATTGAGGTGCTCTTGTTACTGGGTGT
CTGTGTGCTGTAATTCTGGTTTTGGATATGTTCTGTAAAGATTTTGACAAATGAAAATGTGTTTTTCTCTGTTAAAACTTGTCAGAGTAC
TAGAAGTTGTATCTCTGTAGGTGCAGGTCCATTTCTGCCCACAGGTAGGGTGTTTTTCTTTGATTAAGAGATTGACACTTCTGTTGCCTA
GGACCTCCCAACTCAACCATTTCTAGGTGAAGGCAGAAAAATCCACATTAGTTACTCCTCTTCAGACATTTCAGCTGAGATAACAAATCT
TTTGGAATTTTTTCACCCATAGAAAGAGTGGTAGATATTTGAATTTAGCAGGTGGAGTTTCATAGTAAAAACAGCTTTTGACTCAGCTTT
GATTTATCCTCATTTGATTTGGCCAGAAAGTAGGTAATATGCATTGATTGGCTTCTGATTCCAATTCAGTATAGCAAGGTGCTAGGTTTT
TTCCTTTCCCCACCTGTCTCTTAGCCTGGGGAATTAAATGAGAAGCCTTAGAATGGGTGGCCCTTGTGACCTGAAACACTTCCCACATAA
GCTACTTAACAAGATTGTCATGGAGCTGCAGATTCCATTGCCCACCAAAGACTAGAACACACACATATCCATACACCAAAGGAAAGACAA
TTCTGAAATGCTGTTTCTCTGGTGGTTCCCTCTCTGGCTGCTGCCTCACAGTATGGGAACCTGTACTCTGCAGAGGTGACAGGCCAGATT
TGCATTATCTCACAACCTTAGCCCTTGGTGCTAACTGTCCTACAGTGAAGTGCCTGGGGGGTTGTCCTATCCCATAAGCCACTTGGATGC
TGACAGCAGCCACCATCAGAATGACCCACGCAAAAAAAAGAAAAAAAAAATTAAAAAGTCCCCTCACAACCCAGTGACACCTTTCTGCTT
TCCTCTAGACTGGAACATTGATTAGGGAGTGCCTCAGACATGACATTCTTGTGCTGTCCTTGGAATTAATCTGGCAGCAGGAGGGAGCAG
ACTATGTAAACAGAGATAAAAATTAATTTTCAATATTGAAGGAAAAAAGAAATAAGAAGAGAGAGAGAAAGAAAGCATCACACAAAGATT
TTCTTAAAAGAAACAATTTTGCTTGAAATCTCTTTAGATGGGGCTCATTTCTCACGGTGGCACTTGGCCTCCACTGGGCAGCAGGACCAG
CTCCAAGCGCTAGTGTTCTGTTCTCTTTTTGTAATCTTGGAATCTTTTGTTGCTCTAAATACAATTAAAAATGGCAGAAACTTGTTTGTT
GGACTACATGTGTGACTTTGGGTCTGTCTCTGCCTCTGCTTTCAGAAATGTCATCCATTGTGTAAAATATTGGCTTACTGGTCTGCCAGC
TAAAACTTGGCCACATCCCCTGTTATGGCTGCAGGATCGAGTTATTGTTAACAAAGAGACCCAAGAAAAGCTGCTAATGTCCTCTTATCA

>94274_94274_1_TRMT10B-AR_TRMT10B_chr9_37776402_ENST00000297994_AR_chrX_66905852_ENST00000374690_length(amino acids)=612AA_BP=281
MDWKLEGSTQKVESPVLQGQEGILEETGEDGLPEGFQLLQIDAEGECQEGEILATGSTAWCSKNVQRKQRHWEKIVAAKKSKRKQEKERR
KANRAENPGICPQHSKRFLRALTKDKLLEAKHSGPRLCIDLSMTHYMSKKELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEEC
VRMNDGFSSYLLDITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQKKVTFQKAREYSVKTARLPIQEYMVRNQNGK
NYHSEILAINQGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGY
ECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNV
NSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRK

--------------------------------------------------------------
>94274_94274_2_TRMT10B-AR_TRMT10B_chr9_37776402_ENST00000377753_AR_chrX_66905852_ENST00000374690_length(transcript)=8458nt_BP=685nt
GGATCCGATGCGCGCCGCTGCCGCTGCGTGGGGGTGAGGGGATCAGTCTGGTGGAAAGGACAGAGGACTAAGTCCATGGACTGGAAATTG
GAAGGGAGTACTCAGAAAGTAGAGTCACCTGTGCTGCAGGGGCAAGAAGGCATCCTAGAGGAGACAGGTGAAGATGGACTTCCTGAAGGC
TTCCAGCTTCTGCAGATCGATGCGGAAGGCGAGTGCCAGGAGGGAGAGATCCTGGCCACAGGCAGTACGGCATGGTGCTCGGAATTAAGT
AGACTGGCTGGACAGATTCGAAGGTTGTATGGTTCAAACAAAAAAGCTGACAGGCCATTTTGGATCTGCCTCACTGGATTCACAACAGAC
AGTCCCCTTTATGAAGAGTGTGTGAGGATGAATGATGGATTTTCTAGTTACCTGTTAGACATAACAGAAGAAGACTGCTTTAGTTTATTT
CCCTTGGAAACCCTTGTGTACCTGACTCCTGACTCAGAACACGCTCTTGAAGATGTTGATCTAAACAAAGTTTACATCCTCGGTGGGCTT
GTGGATGAAAGCATTCAGAAGAAGGTGACATTTCAAAAGGCCCGGGAATACTCTGTCAAGACCGCACGCTTGCCAATCCAGGAATACATG
GTCAGAAACCAGAATGGGAAAAACTATCATTCAGAGATACTGGCCATCAATCAAGGGAAACAGAAGTACCTGTGCGCCAGCAGAAATGAT
TGCACTATTGATAAATTCCGAAGGAAAAATTGTCCATCTTGTCGTCTTCGGAAATGTTATGAAGCAGGGATGACTCTGGGAGCCCGGAAG
CTGAAGAAACTTGGTAATCTGAAACTACAGGAGGAAGGAGAGGCTTCCAGCACCACCAGCCCCACTGAGGAGACAACCCAGAAGCTGACA
GTGTCACACATTGAAGGCTATGAATGTCAGCCCATCTTTCTGAATGTCCTGGAAGCCATTGAGCCAGGTGTAGTGTGTGCTGGACACGAC
AACAACCAGCCCGACTCCTTTGCAGCCTTGCTCTCTAGCCTCAATGAACTGGGAGAGAGACAGCTTGTACACGTGGTCAAGTGGGCCAAG
GCCTTGCCTGGCTTCCGCAACTTACACGTGGACGACCAGATGGCTGTCATTCAGTACTCCTGGATGGGGCTCATGGTGTTTGCCATGGGC
TGGCGATCCTTCACCAATGTCAACTCCAGGATGCTCTACTTCGCCCCTGATCTGGTTTTCAATGAGTACCGCATGCACAAGTCCCGGATG
TACAGCCAGTGTGTCCGAATGAGGCACCTCTCTCAAGAGTTTGGATGGCTCCAAATCACCCCCCAGGAATTCCTGTGCATGAAAGCACTG
CTACTCTTCAGCATTATTCCAGTGGATGGGCTGAAAAATCAAAAATTCTTTGATGAACTTCGAATGAACTACATCAAGGAACTCGATCGT
ATCATTGCATGCAAAAGAAAAAATCCCACATCCTGCTCAAGACGCTTCTACCAGCTCACCAAGCTCCTGGACTCCGTGCAGCCTATTGCG
AGAGAGCTGCATCAGTTCACTTTTGACCTGCTAATCAAGTCACACATGGTGAGCGTGGACTTTCCGGAAATGATGGCAGAGATCATCTCT
GTGCAAGTGCCCAAGATCCTTTCTGGGAAAGTCAAGCCCATCTATTTCCACACCCAGTGAAGCATTGGAAACCCTATTTCCCCACCCCAG
CTCATGCCCCCTTTCAGATGTCTTCTGCCTGTTATAACTCTGCACTACTCCTCTGCAGTGCCTTGGGGAATTTCCTCTATTGATGTACAG
TCTGTCATGAACATGTTCCTGAATTCTATTTGCTGGGCTTTTTTTTTCTCTTTCTCTCCTTTCTTTTTCTTCTTCCCTCCCTATCTAACC
CTCCCATGGCACCTTCAGACTTTGCTTCCCATTGTGGCTCCTATCTGTGTTTTGAATGGTGTTGTATGCCTTTAAATCTGTGATGATCCT
CATATGGCCCAGTGTCAAGTTGTGCTTGTTTACAGCACTACTCTGTGCCAGCCACACAAACGTTTACTTATCTTATGCCACGGGAAGTTT
AGAGAGCTAAGATTATCTGGGGAAATCAAAACAAAAACAAGCAAACAAAAAAAAAAAGCAAAAACAAAACAAAAAATAAGCCAAAAAACC
TTGCTAGTGTTTTTTCCTCAAAAATAAATAAATAAATAAATAAATACGTACATACATACACACATACATACAAACATATAGAAATCCCCA
AAGAGGCCAATAGTGACGAGAAGGTGAAAATTGCAGGCCCATGGGGAGTTACTGATTTTTTCATCTCCTCCCTCCACGGGAGACTTTATT
TTCTGCCAATGGCTATTGCCATTAGAGGGCAGAGTGACCCCAGAGCTGAGTTGGGCAGGGGGGTGGACAGAGAGGAGAGGACAAGGAGGG
CAATGGAGCATCAGTACCTGCCCACAGCCTTGGTCCCTGGGGGCTAGACTGCTCAACTGTGGAGCAATTCATTATACTGAAAATGTGCTT
GTTGTTGAAAATTTGTCTGCATGTTAATGCCTCACCCCCAAACCCTTTTCTCTCTCACTCTCTGCCTCCAACTTCAGATTGACTTTCAAT
AGTTTTTCTAAGACCTTTGAACTGAATGTTCTCTTCAGCCAAAACTTGGCGACTTCCACAGAAAAGTCTGACCACTGAGAAGAAGGAGAG
CAGAGATTTAACCCTTTGTAAGGCCCCATTTGGATCCAGGTCTGCTTTCTCATGTGTGAGTCAGGGAGGAGCTGGAGCCAGAGGAGAAGA
AAATGATAGCTTGGCTGTTCTCCTGCTTAGGACACTGACTGAATAGTTAAACTCTCACTGCCACTACCTTTTCCCCACCTTTAAAAGACC
TGAATGAAGTTTTCTGCCAAACTCCGTGAAGCCACAAGCACCTTATGTCCTCCCTTCAGTGTTTTGTGGGCCTGAATTTCATCACACTGC
ATTTCAGCCATGGTCATCAAGCCTGTTTGCTTCTTTTGGGCATGTTCACAGATTCTCTGTTAAGAGCCCCCACCACCAAGAAGGTTAGCA
GGCCAACAGCTCTGACATCTATCTGTAGATGCCAGTAGTCACAAAGATTTCTTACCAACTCTCAGATCGCTGGAGCCCTTAGACAAACTG
GAAAGAAGGCATCAAAGGGATCAGGCAAGCTGGGCGTCTTGCCCTTGTCCCCCAGAGATGATACCCTCCCAGCAAGTGGAGAAGTTCTCA
CTTCCTTCTTTAGAGCAGCTAAAGGGGCTACCCAGATCAGGGTTGAAGAGAAAACTCAATTACCAGGGTGGGAAGAATGAAGGCACTAGA
ACCAGAAACCCTGCAAATGCTCTTCTTGTCACCCAGCATATCCACCTGCAGAAGTCATGAGAAGAGAGAAGGAACAAAGAGGAGACTCTG
ACTACTGAATTAAAATCTTCAGCGGCAAAGCCTAAAGCCAGATGGACACCATCTGGTGAGTTTACTCATCATCCTCCTCTGCTGCTGATT
CTGGGCTCTGACATTGCCCATACTCACTCAGATTCCCCACCTTTGTTGCTGCCTCTTAGTCAGAGGGAGGCCAAACCATTGAGACTTTCT
ACAGAACCATGGCTTCTTTCGGAAAGGTCTGGTTGGTGTGGCTCCAATACTTTGCCACCCATGAACTCAGGGTGTGCCCTGGGACACTGG
TTTTATATAGTCTTTTGGCACACCTGTGTTCTGTTGACTTCGTTCTTCAAGCCCAAGTGCAAGGGAAAATGTCCACCTACTTTCTCATCT
TGGCCTCTGCCTCCTTACTTAGCTCTTAATCTCATCTGTTGAACTCAAGAAATCAAGGGCCAGTCATCAAGCTGCCCATTTTAATTGATT
CACTCTGTTTGTTGAGAGGATAGTTTCTGAGTGACATGATATGATCCACAAGGGTTTCCTTCCCTGATTTCTGCATTGATATTAATAGCC
AAACGAACTTCAAAACAGCTTTAAATAACAAGGGAGAGGGGAACCTAAGATGAGTAATATGCCAATCCAAGACTGCTGGAGAAAACTAAA
GCTGACAGGTTCCCTTTTTGGGGTGGGATAGACATGTTCTGGTTTTCTTTATTATTACACAATCTGGCTCATGTACAGGATCACTTTTAG
CTGTTTTAAACAGAAAAAAATATCCACCACTCTTTTCAGTTACACTAGGTTACATTTTAATAGGTCCTTTACATCTGTTTTGGAATGATT
TTCATCTTTTGTGATACACAGATTGAATTATATCATTTTCATATCTCTCCTTGTAAATACTAGAAGCTCTCCTTTACATTTCTCTATCAA
ATTTTTCATCTTTATGGGTTTCCCAATTGTGACTCTTGTCTTCATGAATATATGTTTTTCATTTGCAAAAGCCAAAAATCAGTGAAACAG
CAGTGTAATTAAAAGCAACAACTGGATTACTCCAAATTTCCAAATGACAAAACTAGGGAAAAATAGCCTACACAAGCCTTTAGGCCTACT
CTTTCTGTGCTTGGGTTTGAGTGAACAAAGGAGATTTTAGCTTGGCTCTGTTCTCCCATGGATGAAAGGAGGAGGATTTTTTTTTTCTTT
TGGCCATTGATGTTCTAGCCAATGTAATTGACAGAAGTCTCATTTTGCATGCGCTCTGCTCTACAAACAGAGTTGGTATGGTTGGTATAC
TGTACTCACCTGTGAGGGACTGGCCACTCAGACCCACTTAGCTGGTGAGCTAGAAGATGAGGATCACTCACTGGAAAAGTCACAAGGACC
ATCTCCAAACAAGTTGGCAGTGCTCGATGTGGACGAAGAGTGAGGAAGAGAAAAAGAAGGAGCACCAGGGAGAAGGCTCCGTCTGTGCTG
GGCAGCAGACAGCTGCCAGGATCACGAACTCTGTAGTCAAAGAAAAGAGTCGTGTGGCAGTTTCAGCTCTCGTTCATTGGGCAGCTCGCC
TAGGCCCAGCCTCTGAGCTGACATGGGAGTTGTTGGATTCTTTGTTTCATAGCTTTTTCTATGCCATAGGCAATATTGTTGTTCTTGGAA
AGTTTATTATTTTTTTAACTCCCTTACTCTGAGAAAGGGATATTTTGAAGGACTGTCATATATCTTTGAAAAAAGAAAATCTGTAATACA
TATATTTTTATGTATGTTCACTGGCACTAAAAAATATAGAGAGCTTCATTCTGTCCTTTGGGTAGTTGCTGAGGTAATTGTCCAGGTTGA
AAAATAATGTGCTGATGCTAGAGTCCCTCTCTGTCCATACTCTACTTCTAAATACATATAGGCATACATAGCAAGTTTTATTTGACTTGT
ACTTTAAGAGAAAATATGTCCACCATCCACATGATGCACAAATGAGCTAACATTGAGCTTCAAGTAGCTTCTAAGTGTTTGTTTCATTAG
GCACAGCACAGATGTGGCCTTTCCCCCCTTCTCTCCCTTGATATCTGGCAGGGCATAAAGGCCCAGGCCACTTCCTCTGCCCCTTCCCAG
CCCTGCACCAAAGCTGCATTTCAGGAGACTCTCTCCAGACAGCCCAGTAACTACCCGAGCATGGCCCCTGCATAGCCCTGGAAAAATAAG
AGGCTGACTGTCTACGAATTATCTTGTGCCAGTTGCCCAGGTGAGAGGGCACTGGGCCAAGGGAGTGGTTTTCATGTTTGACCCACTACA
AGGGGTCATGGGAATCAGGAATGCCAAAGCACCAGATCAAATCCAAAACTTAAAGTCAAAATAAGCCATTCAGCATGTTCAGTTTCTTGG
AAAAGGAAGTTTCTACCCCTGATGCCTTTGTAGGCAGATCTGTTCTCACCATTAATCTTTTTGAAAATCTTTTAAAGCAGTTTTTAAAAA
GAGAGATGAAAGCATCACATTATATAACCAAAGATTACATTGTACCTGCTAAGATACCAAAATTCATAAGGGCAGGGGGGGAGCAAGCAT
TAGTGCCTCTTTGATAAGCTGTCCAAAGACAGACTAAAGGACTCTGCTGGTGACTGACTTATAAGAGCTTTGTGGGTTTTTTTTTCCCTA
ATAATATACATGTTTAGAAGAATTGAAAATAATTTCGGGAAAATGGGATTATGGGTCCTTCACTAAGTGATTTTATAAGCAGAACTGGCT
TTCCTTTTCTCTAGTAGTTGCTGAGCAAATTGTTGAAGCTCCATCATTGCATGGTTGGAAATGGAGCTGTTCTTAGCCACTGTGTTTGCT
AGTGCCCATGTTAGCTTATCTGAAGATGTGAAACCCTTGCTGATAAGGGAGCATTTAAAGTACTAGATTTTGCACTAGAGGGACAGCAGG
CAGAAATCCTTATTTCTGCCCACTTTGGATGGCACAAAAAGTTATCTGCAGTTGAAGGCAGAAAGTTGAAATACATTGTAAATGAATATT
TGTATCCATGTTTCAAAATTGAAATATATATATATATATATATATATATATATATATATATATAGTGTGTGTGTGTGTTCTGATAGCTTT
AACTTTCTCTGCATCTTTATATTTGGTTCCAGATCACACCTGATGCCATGTACTTGTGAGAGAGGATGCAGTTTTGTTTTGGAAGCTCTC
TCAGAACAAACAAGACACCTGGATTGATCAGTTAACTAAAAGTTTTCTCCCCTATTGGGTTTGACCCACAGGTCCTGTGAAGGAGCAGAG
GGATAAAAAGAGTAGAGGACATGATACATTGTACTTTACTAGTTCAAGACAGATGAATGTGGAAAGCATAAAAACTCAATGGAACTGACT
GAGATTTACCACAGGGAAGGCCCAAACTTGGGGCCAAAAGCCTACCCAAGTGATTGACCAGTGGCCCCCTAATGGGACCTGAGCTGTTGG
AAGAAGAGAACTGTTCCTTGGTCTTCACCATCCTTGTGAGAGAAGGGCAGTTTCCTGCATTGGAACCTGGAGCAAGCGCTCTATCTTTCA
CACAAATTCCCTCACCTGAGATTGAGGTGCTCTTGTTACTGGGTGTCTGTGTGCTGTAATTCTGGTTTTGGATATGTTCTGTAAAGATTT
TGACAAATGAAAATGTGTTTTTCTCTGTTAAAACTTGTCAGAGTACTAGAAGTTGTATCTCTGTAGGTGCAGGTCCATTTCTGCCCACAG
GTAGGGTGTTTTTCTTTGATTAAGAGATTGACACTTCTGTTGCCTAGGACCTCCCAACTCAACCATTTCTAGGTGAAGGCAGAAAAATCC
ACATTAGTTACTCCTCTTCAGACATTTCAGCTGAGATAACAAATCTTTTGGAATTTTTTCACCCATAGAAAGAGTGGTAGATATTTGAAT
TTAGCAGGTGGAGTTTCATAGTAAAAACAGCTTTTGACTCAGCTTTGATTTATCCTCATTTGATTTGGCCAGAAAGTAGGTAATATGCAT
TGATTGGCTTCTGATTCCAATTCAGTATAGCAAGGTGCTAGGTTTTTTCCTTTCCCCACCTGTCTCTTAGCCTGGGGAATTAAATGAGAA
GCCTTAGAATGGGTGGCCCTTGTGACCTGAAACACTTCCCACATAAGCTACTTAACAAGATTGTCATGGAGCTGCAGATTCCATTGCCCA
CCAAAGACTAGAACACACACATATCCATACACCAAAGGAAAGACAATTCTGAAATGCTGTTTCTCTGGTGGTTCCCTCTCTGGCTGCTGC
CTCACAGTATGGGAACCTGTACTCTGCAGAGGTGACAGGCCAGATTTGCATTATCTCACAACCTTAGCCCTTGGTGCTAACTGTCCTACA
GTGAAGTGCCTGGGGGGTTGTCCTATCCCATAAGCCACTTGGATGCTGACAGCAGCCACCATCAGAATGACCCACGCAAAAAAAAGAAAA
AAAAAATTAAAAAGTCCCCTCACAACCCAGTGACACCTTTCTGCTTTCCTCTAGACTGGAACATTGATTAGGGAGTGCCTCAGACATGAC
ATTCTTGTGCTGTCCTTGGAATTAATCTGGCAGCAGGAGGGAGCAGACTATGTAAACAGAGATAAAAATTAATTTTCAATATTGAAGGAA
AAAAGAAATAAGAAGAGAGAGAGAAAGAAAGCATCACACAAAGATTTTCTTAAAAGAAACAATTTTGCTTGAAATCTCTTTAGATGGGGC
TCATTTCTCACGGTGGCACTTGGCCTCCACTGGGCAGCAGGACCAGCTCCAAGCGCTAGTGTTCTGTTCTCTTTTTGTAATCTTGGAATC
TTTTGTTGCTCTAAATACAATTAAAAATGGCAGAAACTTGTTTGTTGGACTACATGTGTGACTTTGGGTCTGTCTCTGCCTCTGCTTTCA
GAAATGTCATCCATTGTGTAAAATATTGGCTTACTGGTCTGCCAGCTAAAACTTGGCCACATCCCCTGTTATGGCTGCAGGATCGAGTTA

>94274_94274_2_TRMT10B-AR_TRMT10B_chr9_37776402_ENST00000377753_AR_chrX_66905852_ENST00000374690_length(amino acids)=534AA_BP=203
MDWKLEGSTQKVESPVLQGQEGILEETGEDGLPEGFQLLQIDAEGECQEGEILATGSTAWCSELSRLAGQIRRLYGSNKKADRPFWICLT
GFTTDSPLYEECVRMNDGFSSYLLDITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQKKVTFQKAREYSVKTARLP
IQEYMVRNQNGKNYHSEILAINQGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEET
TQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLM
VFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYI

--------------------------------------------------------------
>94274_94274_3_TRMT10B-AR_TRMT10B_chr9_37776402_ENST00000377754_AR_chrX_66905852_ENST00000374690_length(transcript)=8573nt_BP=800nt
CGCGCCGCTGCCGCTGCGTGGGGGTGAGGGGATCAGTCTGGTGGAAAGGACAGAGGACTAAGTCCATGGACTGGAAATTGGAAGGGAGTA
CTCAGAAAGTAGAGTCACCTGTGCTGCAGGGGCAAGAAGGCATCCTAGAGGAGACAGGTGAAGATGGACTTCCTGAAGGCTTCCAGCTTC
TGCAGATCGATGCGGAAGGCGAGTGCCAGGAGGGAGAGATCCTGGCCACAGGCAGTACGGCATGGTGCTCGGCATTTGCCCCCAGCACAG
CAAACGTTTCCTGAGAGCTCTAACCAAAGACAAACTTTTGGAAGCCAAACACTCAGGACCAAGACTATGTATCGATTTGAGTATGACCCA
CTACATGTCAAAGAAGGAATTAAGTAGACTGGCTGGACAGATTCGAAGGTTGTATGGTTCAAACAAAAAAGCTGACAGGCCATTTTGGAT
CTGCCTCACTGGATTCACAACAGACAGTCCCCTTTATGAAGAGTGTGTGAGGATGAATGATGGATTTTCTAGTTACCTGTTAGACATAAC
AGAAGAAGACTGCTTTAGTTTATTTCCCTTGGAAACCCTTGTGTACCTGACTCCTGACTCAGAACACGCTCTTGAAGATGTTGATCTAAA
CAAAGTTTACATCCTCGGTGGGCTTGTGGATGAAAGCATTCAGAAGAAGGTGACATTTCAAAAGGCCCGGGAATACTCTGTCAAGACCGC
ACGCTTGCCAATCCAGGAATACATGGTCAGAAACCAGAATGGGAAAAACTATCATTCAGAGATACTGGCCATCAATCAAGGGAAACAGAA
GTACCTGTGCGCCAGCAGAAATGATTGCACTATTGATAAATTCCGAAGGAAAAATTGTCCATCTTGTCGTCTTCGGAAATGTTATGAAGC
AGGGATGACTCTGGGAGCCCGGAAGCTGAAGAAACTTGGTAATCTGAAACTACAGGAGGAAGGAGAGGCTTCCAGCACCACCAGCCCCAC
TGAGGAGACAACCCAGAAGCTGACAGTGTCACACATTGAAGGCTATGAATGTCAGCCCATCTTTCTGAATGTCCTGGAAGCCATTGAGCC
AGGTGTAGTGTGTGCTGGACACGACAACAACCAGCCCGACTCCTTTGCAGCCTTGCTCTCTAGCCTCAATGAACTGGGAGAGAGACAGCT
TGTACACGTGGTCAAGTGGGCCAAGGCCTTGCCTGGCTTCCGCAACTTACACGTGGACGACCAGATGGCTGTCATTCAGTACTCCTGGAT
GGGGCTCATGGTGTTTGCCATGGGCTGGCGATCCTTCACCAATGTCAACTCCAGGATGCTCTACTTCGCCCCTGATCTGGTTTTCAATGA
GTACCGCATGCACAAGTCCCGGATGTACAGCCAGTGTGTCCGAATGAGGCACCTCTCTCAAGAGTTTGGATGGCTCCAAATCACCCCCCA
GGAATTCCTGTGCATGAAAGCACTGCTACTCTTCAGCATTATTCCAGTGGATGGGCTGAAAAATCAAAAATTCTTTGATGAACTTCGAAT
GAACTACATCAAGGAACTCGATCGTATCATTGCATGCAAAAGAAAAAATCCCACATCCTGCTCAAGACGCTTCTACCAGCTCACCAAGCT
CCTGGACTCCGTGCAGCCTATTGCGAGAGAGCTGCATCAGTTCACTTTTGACCTGCTAATCAAGTCACACATGGTGAGCGTGGACTTTCC
GGAAATGATGGCAGAGATCATCTCTGTGCAAGTGCCCAAGATCCTTTCTGGGAAAGTCAAGCCCATCTATTTCCACACCCAGTGAAGCAT
TGGAAACCCTATTTCCCCACCCCAGCTCATGCCCCCTTTCAGATGTCTTCTGCCTGTTATAACTCTGCACTACTCCTCTGCAGTGCCTTG
GGGAATTTCCTCTATTGATGTACAGTCTGTCATGAACATGTTCCTGAATTCTATTTGCTGGGCTTTTTTTTTCTCTTTCTCTCCTTTCTT
TTTCTTCTTCCCTCCCTATCTAACCCTCCCATGGCACCTTCAGACTTTGCTTCCCATTGTGGCTCCTATCTGTGTTTTGAATGGTGTTGT
ATGCCTTTAAATCTGTGATGATCCTCATATGGCCCAGTGTCAAGTTGTGCTTGTTTACAGCACTACTCTGTGCCAGCCACACAAACGTTT
ACTTATCTTATGCCACGGGAAGTTTAGAGAGCTAAGATTATCTGGGGAAATCAAAACAAAAACAAGCAAACAAAAAAAAAAAGCAAAAAC
AAAACAAAAAATAAGCCAAAAAACCTTGCTAGTGTTTTTTCCTCAAAAATAAATAAATAAATAAATAAATACGTACATACATACACACAT
ACATACAAACATATAGAAATCCCCAAAGAGGCCAATAGTGACGAGAAGGTGAAAATTGCAGGCCCATGGGGAGTTACTGATTTTTTCATC
TCCTCCCTCCACGGGAGACTTTATTTTCTGCCAATGGCTATTGCCATTAGAGGGCAGAGTGACCCCAGAGCTGAGTTGGGCAGGGGGGTG
GACAGAGAGGAGAGGACAAGGAGGGCAATGGAGCATCAGTACCTGCCCACAGCCTTGGTCCCTGGGGGCTAGACTGCTCAACTGTGGAGC
AATTCATTATACTGAAAATGTGCTTGTTGTTGAAAATTTGTCTGCATGTTAATGCCTCACCCCCAAACCCTTTTCTCTCTCACTCTCTGC
CTCCAACTTCAGATTGACTTTCAATAGTTTTTCTAAGACCTTTGAACTGAATGTTCTCTTCAGCCAAAACTTGGCGACTTCCACAGAAAA
GTCTGACCACTGAGAAGAAGGAGAGCAGAGATTTAACCCTTTGTAAGGCCCCATTTGGATCCAGGTCTGCTTTCTCATGTGTGAGTCAGG
GAGGAGCTGGAGCCAGAGGAGAAGAAAATGATAGCTTGGCTGTTCTCCTGCTTAGGACACTGACTGAATAGTTAAACTCTCACTGCCACT
ACCTTTTCCCCACCTTTAAAAGACCTGAATGAAGTTTTCTGCCAAACTCCGTGAAGCCACAAGCACCTTATGTCCTCCCTTCAGTGTTTT
GTGGGCCTGAATTTCATCACACTGCATTTCAGCCATGGTCATCAAGCCTGTTTGCTTCTTTTGGGCATGTTCACAGATTCTCTGTTAAGA
GCCCCCACCACCAAGAAGGTTAGCAGGCCAACAGCTCTGACATCTATCTGTAGATGCCAGTAGTCACAAAGATTTCTTACCAACTCTCAG
ATCGCTGGAGCCCTTAGACAAACTGGAAAGAAGGCATCAAAGGGATCAGGCAAGCTGGGCGTCTTGCCCTTGTCCCCCAGAGATGATACC
CTCCCAGCAAGTGGAGAAGTTCTCACTTCCTTCTTTAGAGCAGCTAAAGGGGCTACCCAGATCAGGGTTGAAGAGAAAACTCAATTACCA
GGGTGGGAAGAATGAAGGCACTAGAACCAGAAACCCTGCAAATGCTCTTCTTGTCACCCAGCATATCCACCTGCAGAAGTCATGAGAAGA
GAGAAGGAACAAAGAGGAGACTCTGACTACTGAATTAAAATCTTCAGCGGCAAAGCCTAAAGCCAGATGGACACCATCTGGTGAGTTTAC
TCATCATCCTCCTCTGCTGCTGATTCTGGGCTCTGACATTGCCCATACTCACTCAGATTCCCCACCTTTGTTGCTGCCTCTTAGTCAGAG
GGAGGCCAAACCATTGAGACTTTCTACAGAACCATGGCTTCTTTCGGAAAGGTCTGGTTGGTGTGGCTCCAATACTTTGCCACCCATGAA
CTCAGGGTGTGCCCTGGGACACTGGTTTTATATAGTCTTTTGGCACACCTGTGTTCTGTTGACTTCGTTCTTCAAGCCCAAGTGCAAGGG
AAAATGTCCACCTACTTTCTCATCTTGGCCTCTGCCTCCTTACTTAGCTCTTAATCTCATCTGTTGAACTCAAGAAATCAAGGGCCAGTC
ATCAAGCTGCCCATTTTAATTGATTCACTCTGTTTGTTGAGAGGATAGTTTCTGAGTGACATGATATGATCCACAAGGGTTTCCTTCCCT
GATTTCTGCATTGATATTAATAGCCAAACGAACTTCAAAACAGCTTTAAATAACAAGGGAGAGGGGAACCTAAGATGAGTAATATGCCAA
TCCAAGACTGCTGGAGAAAACTAAAGCTGACAGGTTCCCTTTTTGGGGTGGGATAGACATGTTCTGGTTTTCTTTATTATTACACAATCT
GGCTCATGTACAGGATCACTTTTAGCTGTTTTAAACAGAAAAAAATATCCACCACTCTTTTCAGTTACACTAGGTTACATTTTAATAGGT
CCTTTACATCTGTTTTGGAATGATTTTCATCTTTTGTGATACACAGATTGAATTATATCATTTTCATATCTCTCCTTGTAAATACTAGAA
GCTCTCCTTTACATTTCTCTATCAAATTTTTCATCTTTATGGGTTTCCCAATTGTGACTCTTGTCTTCATGAATATATGTTTTTCATTTG
CAAAAGCCAAAAATCAGTGAAACAGCAGTGTAATTAAAAGCAACAACTGGATTACTCCAAATTTCCAAATGACAAAACTAGGGAAAAATA
GCCTACACAAGCCTTTAGGCCTACTCTTTCTGTGCTTGGGTTTGAGTGAACAAAGGAGATTTTAGCTTGGCTCTGTTCTCCCATGGATGA
AAGGAGGAGGATTTTTTTTTTCTTTTGGCCATTGATGTTCTAGCCAATGTAATTGACAGAAGTCTCATTTTGCATGCGCTCTGCTCTACA
AACAGAGTTGGTATGGTTGGTATACTGTACTCACCTGTGAGGGACTGGCCACTCAGACCCACTTAGCTGGTGAGCTAGAAGATGAGGATC
ACTCACTGGAAAAGTCACAAGGACCATCTCCAAACAAGTTGGCAGTGCTCGATGTGGACGAAGAGTGAGGAAGAGAAAAAGAAGGAGCAC
CAGGGAGAAGGCTCCGTCTGTGCTGGGCAGCAGACAGCTGCCAGGATCACGAACTCTGTAGTCAAAGAAAAGAGTCGTGTGGCAGTTTCA
GCTCTCGTTCATTGGGCAGCTCGCCTAGGCCCAGCCTCTGAGCTGACATGGGAGTTGTTGGATTCTTTGTTTCATAGCTTTTTCTATGCC
ATAGGCAATATTGTTGTTCTTGGAAAGTTTATTATTTTTTTAACTCCCTTACTCTGAGAAAGGGATATTTTGAAGGACTGTCATATATCT
TTGAAAAAAGAAAATCTGTAATACATATATTTTTATGTATGTTCACTGGCACTAAAAAATATAGAGAGCTTCATTCTGTCCTTTGGGTAG
TTGCTGAGGTAATTGTCCAGGTTGAAAAATAATGTGCTGATGCTAGAGTCCCTCTCTGTCCATACTCTACTTCTAAATACATATAGGCAT
ACATAGCAAGTTTTATTTGACTTGTACTTTAAGAGAAAATATGTCCACCATCCACATGATGCACAAATGAGCTAACATTGAGCTTCAAGT
AGCTTCTAAGTGTTTGTTTCATTAGGCACAGCACAGATGTGGCCTTTCCCCCCTTCTCTCCCTTGATATCTGGCAGGGCATAAAGGCCCA
GGCCACTTCCTCTGCCCCTTCCCAGCCCTGCACCAAAGCTGCATTTCAGGAGACTCTCTCCAGACAGCCCAGTAACTACCCGAGCATGGC
CCCTGCATAGCCCTGGAAAAATAAGAGGCTGACTGTCTACGAATTATCTTGTGCCAGTTGCCCAGGTGAGAGGGCACTGGGCCAAGGGAG
TGGTTTTCATGTTTGACCCACTACAAGGGGTCATGGGAATCAGGAATGCCAAAGCACCAGATCAAATCCAAAACTTAAAGTCAAAATAAG
CCATTCAGCATGTTCAGTTTCTTGGAAAAGGAAGTTTCTACCCCTGATGCCTTTGTAGGCAGATCTGTTCTCACCATTAATCTTTTTGAA
AATCTTTTAAAGCAGTTTTTAAAAAGAGAGATGAAAGCATCACATTATATAACCAAAGATTACATTGTACCTGCTAAGATACCAAAATTC
ATAAGGGCAGGGGGGGAGCAAGCATTAGTGCCTCTTTGATAAGCTGTCCAAAGACAGACTAAAGGACTCTGCTGGTGACTGACTTATAAG
AGCTTTGTGGGTTTTTTTTTCCCTAATAATATACATGTTTAGAAGAATTGAAAATAATTTCGGGAAAATGGGATTATGGGTCCTTCACTA
AGTGATTTTATAAGCAGAACTGGCTTTCCTTTTCTCTAGTAGTTGCTGAGCAAATTGTTGAAGCTCCATCATTGCATGGTTGGAAATGGA
GCTGTTCTTAGCCACTGTGTTTGCTAGTGCCCATGTTAGCTTATCTGAAGATGTGAAACCCTTGCTGATAAGGGAGCATTTAAAGTACTA
GATTTTGCACTAGAGGGACAGCAGGCAGAAATCCTTATTTCTGCCCACTTTGGATGGCACAAAAAGTTATCTGCAGTTGAAGGCAGAAAG
TTGAAATACATTGTAAATGAATATTTGTATCCATGTTTCAAAATTGAAATATATATATATATATATATATATATATATATATATATATAG
TGTGTGTGTGTGTTCTGATAGCTTTAACTTTCTCTGCATCTTTATATTTGGTTCCAGATCACACCTGATGCCATGTACTTGTGAGAGAGG
ATGCAGTTTTGTTTTGGAAGCTCTCTCAGAACAAACAAGACACCTGGATTGATCAGTTAACTAAAAGTTTTCTCCCCTATTGGGTTTGAC
CCACAGGTCCTGTGAAGGAGCAGAGGGATAAAAAGAGTAGAGGACATGATACATTGTACTTTACTAGTTCAAGACAGATGAATGTGGAAA
GCATAAAAACTCAATGGAACTGACTGAGATTTACCACAGGGAAGGCCCAAACTTGGGGCCAAAAGCCTACCCAAGTGATTGACCAGTGGC
CCCCTAATGGGACCTGAGCTGTTGGAAGAAGAGAACTGTTCCTTGGTCTTCACCATCCTTGTGAGAGAAGGGCAGTTTCCTGCATTGGAA
CCTGGAGCAAGCGCTCTATCTTTCACACAAATTCCCTCACCTGAGATTGAGGTGCTCTTGTTACTGGGTGTCTGTGTGCTGTAATTCTGG
TTTTGGATATGTTCTGTAAAGATTTTGACAAATGAAAATGTGTTTTTCTCTGTTAAAACTTGTCAGAGTACTAGAAGTTGTATCTCTGTA
GGTGCAGGTCCATTTCTGCCCACAGGTAGGGTGTTTTTCTTTGATTAAGAGATTGACACTTCTGTTGCCTAGGACCTCCCAACTCAACCA
TTTCTAGGTGAAGGCAGAAAAATCCACATTAGTTACTCCTCTTCAGACATTTCAGCTGAGATAACAAATCTTTTGGAATTTTTTCACCCA
TAGAAAGAGTGGTAGATATTTGAATTTAGCAGGTGGAGTTTCATAGTAAAAACAGCTTTTGACTCAGCTTTGATTTATCCTCATTTGATT
TGGCCAGAAAGTAGGTAATATGCATTGATTGGCTTCTGATTCCAATTCAGTATAGCAAGGTGCTAGGTTTTTTCCTTTCCCCACCTGTCT
CTTAGCCTGGGGAATTAAATGAGAAGCCTTAGAATGGGTGGCCCTTGTGACCTGAAACACTTCCCACATAAGCTACTTAACAAGATTGTC
ATGGAGCTGCAGATTCCATTGCCCACCAAAGACTAGAACACACACATATCCATACACCAAAGGAAAGACAATTCTGAAATGCTGTTTCTC
TGGTGGTTCCCTCTCTGGCTGCTGCCTCACAGTATGGGAACCTGTACTCTGCAGAGGTGACAGGCCAGATTTGCATTATCTCACAACCTT
AGCCCTTGGTGCTAACTGTCCTACAGTGAAGTGCCTGGGGGGTTGTCCTATCCCATAAGCCACTTGGATGCTGACAGCAGCCACCATCAG
AATGACCCACGCAAAAAAAAGAAAAAAAAAATTAAAAAGTCCCCTCACAACCCAGTGACACCTTTCTGCTTTCCTCTAGACTGGAACATT
GATTAGGGAGTGCCTCAGACATGACATTCTTGTGCTGTCCTTGGAATTAATCTGGCAGCAGGAGGGAGCAGACTATGTAAACAGAGATAA
AAATTAATTTTCAATATTGAAGGAAAAAAGAAATAAGAAGAGAGAGAGAAAGAAAGCATCACACAAAGATTTTCTTAAAAGAAACAATTT
TGCTTGAAATCTCTTTAGATGGGGCTCATTTCTCACGGTGGCACTTGGCCTCCACTGGGCAGCAGGACCAGCTCCAAGCGCTAGTGTTCT
GTTCTCTTTTTGTAATCTTGGAATCTTTTGTTGCTCTAAATACAATTAAAAATGGCAGAAACTTGTTTGTTGGACTACATGTGTGACTTT
GGGTCTGTCTCTGCCTCTGCTTTCAGAAATGTCATCCATTGTGTAAAATATTGGCTTACTGGTCTGCCAGCTAAAACTTGGCCACATCCC
CTGTTATGGCTGCAGGATCGAGTTATTGTTAACAAAGAGACCCAAGAAAAGCTGCTAATGTCCTCTTATCATTGTTGTTAATTTGTTAAA

>94274_94274_3_TRMT10B-AR_TRMT10B_chr9_37776402_ENST00000377754_AR_chrX_66905852_ENST00000374690_length(amino acids)=517AA_BP=186
MVLGICPQHSKRFLRALTKDKLLEAKHSGPRLCIDLSMTHYMSKKELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEECVRMND
GFSSYLLDITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQKKVTFQKAREYSVKTARLPIQEYMVRNQNGKNYHSE
ILAINQGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPI
FLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRML
YFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSC

--------------------------------------------------------------
>94274_94274_4_TRMT10B-AR_TRMT10B_chr9_37776402_ENST00000537911_AR_chrX_66905852_ENST00000374690_length(transcript)=8533nt_BP=760nt
GATGCGCGCCGCTGCCGCTGCGTGGGGGTGAGGGGATCAGTCTGGTGGAAAGGACAGAGGACTAAGTCCATGGACTGGAAATTGGAAGGG
AGTACTCAGAAAGTAGAGTCACCTGTGCTGCAGGGGCAAGAAGGCATCCTAGAGGAGACAGGTGAAGATGGACTTCCTGAAGGCTTCCAG
CTTCTGCAGATCGATGCGGAAGGCGAGTGCCAGGAGGGAGAGATCCTGGCCACAGGCAGTACGGCATGGTGCTCGAAAAATGTCCAGAGA
AAACAGAGACACTGGGAAAAGATAGTTGCAGCAAAGAAGAGCAAAAGAAAGCAAGAAAAAGAACGAAGAAAAGCCAATCGTGCAGAAAAT
CCAGGCATTTGCCCCCAGCACAGCAAACGTTTCCTGAGAGCTCTAACCAAAGACAAACTTTTGGAAGCCAAACACTCAGGACCAAGACTA
TGTATCGATTTGAGTATGACCCACTACATGTCAAAGAAGTTAGACATAACAGAAGAAGACTGCTTTAGTTTATTTCCCTTGGAAACCCTT
GTGTACCTGACTCCTGACTCAGAACACGCTCTTGAAGATGTTGATCTAAACAAAGTTTACATCCTCGGTGGGCTTGTGGATGAAAGCATT
CAGAAGAAGGTGACATTTCAAAAGGCCCGGGAATACTCTGTCAAGACCGCACGCTTGCCAATCCAGGAATACATGGTCAGAAACCAGAAT
GGGAAAAACTATCATTCAGAGATACTGGCCATCAATCAAGGGAAACAGAAGTACCTGTGCGCCAGCAGAAATGATTGCACTATTGATAAA
TTCCGAAGGAAAAATTGTCCATCTTGTCGTCTTCGGAAATGTTATGAAGCAGGGATGACTCTGGGAGCCCGGAAGCTGAAGAAACTTGGT
AATCTGAAACTACAGGAGGAAGGAGAGGCTTCCAGCACCACCAGCCCCACTGAGGAGACAACCCAGAAGCTGACAGTGTCACACATTGAA
GGCTATGAATGTCAGCCCATCTTTCTGAATGTCCTGGAAGCCATTGAGCCAGGTGTAGTGTGTGCTGGACACGACAACAACCAGCCCGAC
TCCTTTGCAGCCTTGCTCTCTAGCCTCAATGAACTGGGAGAGAGACAGCTTGTACACGTGGTCAAGTGGGCCAAGGCCTTGCCTGGCTTC
CGCAACTTACACGTGGACGACCAGATGGCTGTCATTCAGTACTCCTGGATGGGGCTCATGGTGTTTGCCATGGGCTGGCGATCCTTCACC
AATGTCAACTCCAGGATGCTCTACTTCGCCCCTGATCTGGTTTTCAATGAGTACCGCATGCACAAGTCCCGGATGTACAGCCAGTGTGTC
CGAATGAGGCACCTCTCTCAAGAGTTTGGATGGCTCCAAATCACCCCCCAGGAATTCCTGTGCATGAAAGCACTGCTACTCTTCAGCATT
ATTCCAGTGGATGGGCTGAAAAATCAAAAATTCTTTGATGAACTTCGAATGAACTACATCAAGGAACTCGATCGTATCATTGCATGCAAA
AGAAAAAATCCCACATCCTGCTCAAGACGCTTCTACCAGCTCACCAAGCTCCTGGACTCCGTGCAGCCTATTGCGAGAGAGCTGCATCAG
TTCACTTTTGACCTGCTAATCAAGTCACACATGGTGAGCGTGGACTTTCCGGAAATGATGGCAGAGATCATCTCTGTGCAAGTGCCCAAG
ATCCTTTCTGGGAAAGTCAAGCCCATCTATTTCCACACCCAGTGAAGCATTGGAAACCCTATTTCCCCACCCCAGCTCATGCCCCCTTTC
AGATGTCTTCTGCCTGTTATAACTCTGCACTACTCCTCTGCAGTGCCTTGGGGAATTTCCTCTATTGATGTACAGTCTGTCATGAACATG
TTCCTGAATTCTATTTGCTGGGCTTTTTTTTTCTCTTTCTCTCCTTTCTTTTTCTTCTTCCCTCCCTATCTAACCCTCCCATGGCACCTT
CAGACTTTGCTTCCCATTGTGGCTCCTATCTGTGTTTTGAATGGTGTTGTATGCCTTTAAATCTGTGATGATCCTCATATGGCCCAGTGT
CAAGTTGTGCTTGTTTACAGCACTACTCTGTGCCAGCCACACAAACGTTTACTTATCTTATGCCACGGGAAGTTTAGAGAGCTAAGATTA
TCTGGGGAAATCAAAACAAAAACAAGCAAACAAAAAAAAAAAGCAAAAACAAAACAAAAAATAAGCCAAAAAACCTTGCTAGTGTTTTTT
CCTCAAAAATAAATAAATAAATAAATAAATACGTACATACATACACACATACATACAAACATATAGAAATCCCCAAAGAGGCCAATAGTG
ACGAGAAGGTGAAAATTGCAGGCCCATGGGGAGTTACTGATTTTTTCATCTCCTCCCTCCACGGGAGACTTTATTTTCTGCCAATGGCTA
TTGCCATTAGAGGGCAGAGTGACCCCAGAGCTGAGTTGGGCAGGGGGGTGGACAGAGAGGAGAGGACAAGGAGGGCAATGGAGCATCAGT
ACCTGCCCACAGCCTTGGTCCCTGGGGGCTAGACTGCTCAACTGTGGAGCAATTCATTATACTGAAAATGTGCTTGTTGTTGAAAATTTG
TCTGCATGTTAATGCCTCACCCCCAAACCCTTTTCTCTCTCACTCTCTGCCTCCAACTTCAGATTGACTTTCAATAGTTTTTCTAAGACC
TTTGAACTGAATGTTCTCTTCAGCCAAAACTTGGCGACTTCCACAGAAAAGTCTGACCACTGAGAAGAAGGAGAGCAGAGATTTAACCCT
TTGTAAGGCCCCATTTGGATCCAGGTCTGCTTTCTCATGTGTGAGTCAGGGAGGAGCTGGAGCCAGAGGAGAAGAAAATGATAGCTTGGC
TGTTCTCCTGCTTAGGACACTGACTGAATAGTTAAACTCTCACTGCCACTACCTTTTCCCCACCTTTAAAAGACCTGAATGAAGTTTTCT
GCCAAACTCCGTGAAGCCACAAGCACCTTATGTCCTCCCTTCAGTGTTTTGTGGGCCTGAATTTCATCACACTGCATTTCAGCCATGGTC
ATCAAGCCTGTTTGCTTCTTTTGGGCATGTTCACAGATTCTCTGTTAAGAGCCCCCACCACCAAGAAGGTTAGCAGGCCAACAGCTCTGA
CATCTATCTGTAGATGCCAGTAGTCACAAAGATTTCTTACCAACTCTCAGATCGCTGGAGCCCTTAGACAAACTGGAAAGAAGGCATCAA
AGGGATCAGGCAAGCTGGGCGTCTTGCCCTTGTCCCCCAGAGATGATACCCTCCCAGCAAGTGGAGAAGTTCTCACTTCCTTCTTTAGAG
CAGCTAAAGGGGCTACCCAGATCAGGGTTGAAGAGAAAACTCAATTACCAGGGTGGGAAGAATGAAGGCACTAGAACCAGAAACCCTGCA
AATGCTCTTCTTGTCACCCAGCATATCCACCTGCAGAAGTCATGAGAAGAGAGAAGGAACAAAGAGGAGACTCTGACTACTGAATTAAAA
TCTTCAGCGGCAAAGCCTAAAGCCAGATGGACACCATCTGGTGAGTTTACTCATCATCCTCCTCTGCTGCTGATTCTGGGCTCTGACATT
GCCCATACTCACTCAGATTCCCCACCTTTGTTGCTGCCTCTTAGTCAGAGGGAGGCCAAACCATTGAGACTTTCTACAGAACCATGGCTT
CTTTCGGAAAGGTCTGGTTGGTGTGGCTCCAATACTTTGCCACCCATGAACTCAGGGTGTGCCCTGGGACACTGGTTTTATATAGTCTTT
TGGCACACCTGTGTTCTGTTGACTTCGTTCTTCAAGCCCAAGTGCAAGGGAAAATGTCCACCTACTTTCTCATCTTGGCCTCTGCCTCCT
TACTTAGCTCTTAATCTCATCTGTTGAACTCAAGAAATCAAGGGCCAGTCATCAAGCTGCCCATTTTAATTGATTCACTCTGTTTGTTGA
GAGGATAGTTTCTGAGTGACATGATATGATCCACAAGGGTTTCCTTCCCTGATTTCTGCATTGATATTAATAGCCAAACGAACTTCAAAA
CAGCTTTAAATAACAAGGGAGAGGGGAACCTAAGATGAGTAATATGCCAATCCAAGACTGCTGGAGAAAACTAAAGCTGACAGGTTCCCT
TTTTGGGGTGGGATAGACATGTTCTGGTTTTCTTTATTATTACACAATCTGGCTCATGTACAGGATCACTTTTAGCTGTTTTAAACAGAA
AAAAATATCCACCACTCTTTTCAGTTACACTAGGTTACATTTTAATAGGTCCTTTACATCTGTTTTGGAATGATTTTCATCTTTTGTGAT
ACACAGATTGAATTATATCATTTTCATATCTCTCCTTGTAAATACTAGAAGCTCTCCTTTACATTTCTCTATCAAATTTTTCATCTTTAT
GGGTTTCCCAATTGTGACTCTTGTCTTCATGAATATATGTTTTTCATTTGCAAAAGCCAAAAATCAGTGAAACAGCAGTGTAATTAAAAG
CAACAACTGGATTACTCCAAATTTCCAAATGACAAAACTAGGGAAAAATAGCCTACACAAGCCTTTAGGCCTACTCTTTCTGTGCTTGGG
TTTGAGTGAACAAAGGAGATTTTAGCTTGGCTCTGTTCTCCCATGGATGAAAGGAGGAGGATTTTTTTTTTCTTTTGGCCATTGATGTTC
TAGCCAATGTAATTGACAGAAGTCTCATTTTGCATGCGCTCTGCTCTACAAACAGAGTTGGTATGGTTGGTATACTGTACTCACCTGTGA
GGGACTGGCCACTCAGACCCACTTAGCTGGTGAGCTAGAAGATGAGGATCACTCACTGGAAAAGTCACAAGGACCATCTCCAAACAAGTT
GGCAGTGCTCGATGTGGACGAAGAGTGAGGAAGAGAAAAAGAAGGAGCACCAGGGAGAAGGCTCCGTCTGTGCTGGGCAGCAGACAGCTG
CCAGGATCACGAACTCTGTAGTCAAAGAAAAGAGTCGTGTGGCAGTTTCAGCTCTCGTTCATTGGGCAGCTCGCCTAGGCCCAGCCTCTG
AGCTGACATGGGAGTTGTTGGATTCTTTGTTTCATAGCTTTTTCTATGCCATAGGCAATATTGTTGTTCTTGGAAAGTTTATTATTTTTT
TAACTCCCTTACTCTGAGAAAGGGATATTTTGAAGGACTGTCATATATCTTTGAAAAAAGAAAATCTGTAATACATATATTTTTATGTAT
GTTCACTGGCACTAAAAAATATAGAGAGCTTCATTCTGTCCTTTGGGTAGTTGCTGAGGTAATTGTCCAGGTTGAAAAATAATGTGCTGA
TGCTAGAGTCCCTCTCTGTCCATACTCTACTTCTAAATACATATAGGCATACATAGCAAGTTTTATTTGACTTGTACTTTAAGAGAAAAT
ATGTCCACCATCCACATGATGCACAAATGAGCTAACATTGAGCTTCAAGTAGCTTCTAAGTGTTTGTTTCATTAGGCACAGCACAGATGT
GGCCTTTCCCCCCTTCTCTCCCTTGATATCTGGCAGGGCATAAAGGCCCAGGCCACTTCCTCTGCCCCTTCCCAGCCCTGCACCAAAGCT
GCATTTCAGGAGACTCTCTCCAGACAGCCCAGTAACTACCCGAGCATGGCCCCTGCATAGCCCTGGAAAAATAAGAGGCTGACTGTCTAC
GAATTATCTTGTGCCAGTTGCCCAGGTGAGAGGGCACTGGGCCAAGGGAGTGGTTTTCATGTTTGACCCACTACAAGGGGTCATGGGAAT
CAGGAATGCCAAAGCACCAGATCAAATCCAAAACTTAAAGTCAAAATAAGCCATTCAGCATGTTCAGTTTCTTGGAAAAGGAAGTTTCTA
CCCCTGATGCCTTTGTAGGCAGATCTGTTCTCACCATTAATCTTTTTGAAAATCTTTTAAAGCAGTTTTTAAAAAGAGAGATGAAAGCAT
CACATTATATAACCAAAGATTACATTGTACCTGCTAAGATACCAAAATTCATAAGGGCAGGGGGGGAGCAAGCATTAGTGCCTCTTTGAT
AAGCTGTCCAAAGACAGACTAAAGGACTCTGCTGGTGACTGACTTATAAGAGCTTTGTGGGTTTTTTTTTCCCTAATAATATACATGTTT
AGAAGAATTGAAAATAATTTCGGGAAAATGGGATTATGGGTCCTTCACTAAGTGATTTTATAAGCAGAACTGGCTTTCCTTTTCTCTAGT
AGTTGCTGAGCAAATTGTTGAAGCTCCATCATTGCATGGTTGGAAATGGAGCTGTTCTTAGCCACTGTGTTTGCTAGTGCCCATGTTAGC
TTATCTGAAGATGTGAAACCCTTGCTGATAAGGGAGCATTTAAAGTACTAGATTTTGCACTAGAGGGACAGCAGGCAGAAATCCTTATTT
CTGCCCACTTTGGATGGCACAAAAAGTTATCTGCAGTTGAAGGCAGAAAGTTGAAATACATTGTAAATGAATATTTGTATCCATGTTTCA
AAATTGAAATATATATATATATATATATATATATATATATATATATATAGTGTGTGTGTGTGTTCTGATAGCTTTAACTTTCTCTGCATC
TTTATATTTGGTTCCAGATCACACCTGATGCCATGTACTTGTGAGAGAGGATGCAGTTTTGTTTTGGAAGCTCTCTCAGAACAAACAAGA
CACCTGGATTGATCAGTTAACTAAAAGTTTTCTCCCCTATTGGGTTTGACCCACAGGTCCTGTGAAGGAGCAGAGGGATAAAAAGAGTAG
AGGACATGATACATTGTACTTTACTAGTTCAAGACAGATGAATGTGGAAAGCATAAAAACTCAATGGAACTGACTGAGATTTACCACAGG
GAAGGCCCAAACTTGGGGCCAAAAGCCTACCCAAGTGATTGACCAGTGGCCCCCTAATGGGACCTGAGCTGTTGGAAGAAGAGAACTGTT
CCTTGGTCTTCACCATCCTTGTGAGAGAAGGGCAGTTTCCTGCATTGGAACCTGGAGCAAGCGCTCTATCTTTCACACAAATTCCCTCAC
CTGAGATTGAGGTGCTCTTGTTACTGGGTGTCTGTGTGCTGTAATTCTGGTTTTGGATATGTTCTGTAAAGATTTTGACAAATGAAAATG
TGTTTTTCTCTGTTAAAACTTGTCAGAGTACTAGAAGTTGTATCTCTGTAGGTGCAGGTCCATTTCTGCCCACAGGTAGGGTGTTTTTCT
TTGATTAAGAGATTGACACTTCTGTTGCCTAGGACCTCCCAACTCAACCATTTCTAGGTGAAGGCAGAAAAATCCACATTAGTTACTCCT
CTTCAGACATTTCAGCTGAGATAACAAATCTTTTGGAATTTTTTCACCCATAGAAAGAGTGGTAGATATTTGAATTTAGCAGGTGGAGTT
TCATAGTAAAAACAGCTTTTGACTCAGCTTTGATTTATCCTCATTTGATTTGGCCAGAAAGTAGGTAATATGCATTGATTGGCTTCTGAT
TCCAATTCAGTATAGCAAGGTGCTAGGTTTTTTCCTTTCCCCACCTGTCTCTTAGCCTGGGGAATTAAATGAGAAGCCTTAGAATGGGTG
GCCCTTGTGACCTGAAACACTTCCCACATAAGCTACTTAACAAGATTGTCATGGAGCTGCAGATTCCATTGCCCACCAAAGACTAGAACA
CACACATATCCATACACCAAAGGAAAGACAATTCTGAAATGCTGTTTCTCTGGTGGTTCCCTCTCTGGCTGCTGCCTCACAGTATGGGAA
CCTGTACTCTGCAGAGGTGACAGGCCAGATTTGCATTATCTCACAACCTTAGCCCTTGGTGCTAACTGTCCTACAGTGAAGTGCCTGGGG
GGTTGTCCTATCCCATAAGCCACTTGGATGCTGACAGCAGCCACCATCAGAATGACCCACGCAAAAAAAAGAAAAAAAAAATTAAAAAGT
CCCCTCACAACCCAGTGACACCTTTCTGCTTTCCTCTAGACTGGAACATTGATTAGGGAGTGCCTCAGACATGACATTCTTGTGCTGTCC
TTGGAATTAATCTGGCAGCAGGAGGGAGCAGACTATGTAAACAGAGATAAAAATTAATTTTCAATATTGAAGGAAAAAAGAAATAAGAAG
AGAGAGAGAAAGAAAGCATCACACAAAGATTTTCTTAAAAGAAACAATTTTGCTTGAAATCTCTTTAGATGGGGCTCATTTCTCACGGTG
GCACTTGGCCTCCACTGGGCAGCAGGACCAGCTCCAAGCGCTAGTGTTCTGTTCTCTTTTTGTAATCTTGGAATCTTTTGTTGCTCTAAA
TACAATTAAAAATGGCAGAAACTTGTTTGTTGGACTACATGTGTGACTTTGGGTCTGTCTCTGCCTCTGCTTTCAGAAATGTCATCCATT
GTGTAAAATATTGGCTTACTGGTCTGCCAGCTAAAACTTGGCCACATCCCCTGTTATGGCTGCAGGATCGAGTTATTGTTAACAAAGAGA

>94274_94274_4_TRMT10B-AR_TRMT10B_chr9_37776402_ENST00000537911_AR_chrX_66905852_ENST00000374690_length(amino acids)=561AA_BP=230
MDWKLEGSTQKVESPVLQGQEGILEETGEDGLPEGFQLLQIDAEGECQEGEILATGSTAWCSKNVQRKQRHWEKIVAAKKSKRKQEKERR
KANRAENPGICPQHSKRFLRALTKDKLLEAKHSGPRLCIDLSMTHYMSKKLDITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILG
GLVDESIQKKVTFQKAREYSVKTARLPIQEYMVRNQNGKNYHSEILAINQGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGA
RKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKW
AKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMK
ALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEI

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for TRMT10B-AR


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneARchr9:37776402chrX:66905852ENST0000039604318592_91957.333333333333336389.0CCAR1
TgeneARchr9:37776402chrX:66905852ENST0000039604318572_66257.333333333333336389.0HIPK3
TgeneARchr9:37776402chrX:66905852ENST0000039604318625_91957.333333333333336389.0KAT7
TgeneARchr9:37776402chrX:66905852ENST0000039604318552_91957.333333333333336389.0LPXN


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneARchr9:37776402chrX:66905852ENST00000396043181_58757.333333333333336389.0ZNF318


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for TRMT10B-AR


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for TRMT10B-AR


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource