FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:TRMT11-SLC16A10 (FusionGDB2 ID:94291)

Fusion Gene Summary for TRMT11-SLC16A10

check button Fusion gene summary
Fusion gene informationFusion gene name: TRMT11-SLC16A10
Fusion gene ID: 94291
HgeneTgene
Gene symbol

TRMT11

SLC16A10

Gene ID

60487

117247

Gene nametRNA methyltransferase 11 homologsolute carrier family 16 member 10
SynonymsC6orf75|MDS024|TRM11|TRMT11-1MCT10|PRO0813|TAT1
Cytomap

6q22.32

6q21

Type of geneprotein-codingprotein-coding
DescriptiontRNA (guanine(10)-N2)-methyltransferase homologtRNA guanosine-2'-O-methyltransferase TRM11 homologmonocarboxylate transporter 10MCT 10T-type amino acid transporter 1aromatic amino acid transporter 1solute carrier family 16 (aromatic amino acid transporter), member 10solute carrier family 16 (monocarboxylic acid transporters), member 10solute car
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000489934, ENST00000334379, 
ENST00000368332, ENST00000450358, 
ENST00000368850, ENST00000368851, 
ENST00000465319, 
Fusion gene scores* DoF score11 X 7 X 7=5393 X 3 X 3=27
# samples 143
** MAII scorelog2(14/539*10)=-1.94485844580754
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: TRMT11 [Title/Abstract] AND SLC16A10 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTRMT11(126314968)-SLC16A10(111527795), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across TRMT11 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SLC16A10 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-78-7220-01ATRMT11chr6

126314968

-SLC16A10chr6

111527795

+


Top

Fusion Gene ORF analysis for TRMT11-SLC16A10

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000489934ENST00000368850TRMT11chr6

126314968

-SLC16A10chr6

111527795

+
3UTR-3CDSENST00000489934ENST00000368851TRMT11chr6

126314968

-SLC16A10chr6

111527795

+
3UTR-intronENST00000489934ENST00000465319TRMT11chr6

126314968

-SLC16A10chr6

111527795

+
5CDS-intronENST00000334379ENST00000465319TRMT11chr6

126314968

-SLC16A10chr6

111527795

+
5CDS-intronENST00000368332ENST00000465319TRMT11chr6

126314968

-SLC16A10chr6

111527795

+
5CDS-intronENST00000450358ENST00000465319TRMT11chr6

126314968

-SLC16A10chr6

111527795

+
In-frameENST00000334379ENST00000368850TRMT11chr6

126314968

-SLC16A10chr6

111527795

+
In-frameENST00000334379ENST00000368851TRMT11chr6

126314968

-SLC16A10chr6

111527795

+
In-frameENST00000368332ENST00000368850TRMT11chr6

126314968

-SLC16A10chr6

111527795

+
In-frameENST00000368332ENST00000368851TRMT11chr6

126314968

-SLC16A10chr6

111527795

+
In-frameENST00000450358ENST00000368850TRMT11chr6

126314968

-SLC16A10chr6

111527795

+
In-frameENST00000450358ENST00000368851TRMT11chr6

126314968

-SLC16A10chr6

111527795

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000334379TRMT11chr6126314968-ENST00000368851SLC16A10chr6111527795+165025940864274
ENST00000334379TRMT11chr6126314968-ENST00000368850SLC16A10chr6111527795+982425940864274
ENST00000368332TRMT11chr6126314968-ENST00000368851SLC16A10chr6111527795+16012106815269
ENST00000368332TRMT11chr6126314968-ENST00000368850SLC16A10chr6111527795+97752106815269
ENST00000450358TRMT11chr6126314968-ENST00000368851SLC16A10chr6111527795+165025940864274
ENST00000450358TRMT11chr6126314968-ENST00000368850SLC16A10chr6111527795+982425940864274

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000334379ENST00000368851TRMT11chr6126314968-SLC16A10chr6111527795+0.0005099030.99949
ENST00000334379ENST00000368850TRMT11chr6126314968-SLC16A10chr6111527795+0.000397420.9996026
ENST00000368332ENST00000368851TRMT11chr6126314968-SLC16A10chr6111527795+0.0004409490.999559
ENST00000368332ENST00000368850TRMT11chr6126314968-SLC16A10chr6111527795+0.0003927530.99960726
ENST00000450358ENST00000368851TRMT11chr6126314968-SLC16A10chr6111527795+0.0005099030.99949
ENST00000450358ENST00000368850TRMT11chr6126314968-SLC16A10chr6111527795+0.000397420.9996026

Top

Fusion Genomic Features for TRMT11-SLC16A10


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for TRMT11-SLC16A10


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:126314968/chr6:111527795)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC16A10chr6:126314968chr6:111527795ENST0000036885126473_515314516.0Topological domainCytoplasmic
TgeneSLC16A10chr6:126314968chr6:111527795ENST0000036885126330_350314516.0TransmembraneHelical
TgeneSLC16A10chr6:126314968chr6:111527795ENST0000036885126352_372314516.0TransmembraneHelical
TgeneSLC16A10chr6:126314968chr6:111527795ENST0000036885126397_417314516.0TransmembraneHelical
TgeneSLC16A10chr6:126314968chr6:111527795ENST0000036885126420_440314516.0TransmembraneHelical
TgeneSLC16A10chr6:126314968chr6:111527795ENST0000036885126452_472314516.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC16A10chr6:126314968chr6:111527795ENST00000368851261_66314516.0Topological domainCytoplasmic
TgeneSLC16A10chr6:126314968chr6:111527795ENST0000036885126115_135314516.0TransmembraneHelical
TgeneSLC16A10chr6:126314968chr6:111527795ENST0000036885126145_165314516.0TransmembraneHelical
TgeneSLC16A10chr6:126314968chr6:111527795ENST0000036885126172_192314516.0TransmembraneHelical
TgeneSLC16A10chr6:126314968chr6:111527795ENST0000036885126201_221314516.0TransmembraneHelical
TgeneSLC16A10chr6:126314968chr6:111527795ENST0000036885126229_249314516.0TransmembraneHelical
TgeneSLC16A10chr6:126314968chr6:111527795ENST0000036885126292_312314516.0TransmembraneHelical
TgeneSLC16A10chr6:126314968chr6:111527795ENST000003688512667_87314516.0TransmembraneHelical


Top

Fusion Gene Sequence for TRMT11-SLC16A10


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>94291_94291_1_TRMT11-SLC16A10_TRMT11_chr6_126314968_ENST00000334379_SLC16A10_chr6_111527795_ENST00000368850_length(transcript)=9824nt_BP=259nt
CGCCTGCCTCGCAGAGCTTCCGCTTCCGGCCCTTCAGGCTCTGTCTCTGTGGAGACTGGGCTTTGGGAGGGAGAAAGAGGGACCTAGCGC
GGGCCGCGCAGGCGCACGGTGGGCAGCTGCAATGGCGCTGTCGTGTACCCTTAACAGGTATCTGCTCCTCATGGCGCAGGAGCATCTGGA
GTTCCGCCTGCCGGAAATAAAGTCTTTGCTTTTGCTTTTTGGAGGTCAGTTTGCCAGCAGTCAAGAAACTTATGGAAAGATGAAACATGT
AAATGAAAGATTTCAAGATGAAAAAAATAAAGAGGTTGTTCTCATGTGCATTGGCGTCACTTCAGGAGTTGGACGACTGCTCTTTGGCCG
GATTGCAGATTATGTGCCTGGTGTGAAGAAGGTTTATCTACAGGTACTCTCCTTTTTCTTCATTGGTCTGATGTCCATGATGATTCCTCT
GTGTAGCATCTTTGGGGCCCTCATTGCTGTGTGCCTCATCATGGGTCTCTTCGATGGATGCTTCATTTCCATTATGGCTCCCATAGCCTT
TGAGTTAGTTGGTGCCCAGGATGTCTCCCAAGCAATTGGATTTCTGCTCGGATTCATGTCTATACCCATGACTGTTGGCCCACCCATTGC
AGGGTTACTTCGTGACAAACTGGGCTCCTATGATGTGGCATTCTACCTCGCTGGAGTCCCTCCCCTTATTGGAGGTGCTGTGCTTTGTTT
TATCCCGTGGATCCATAGTAAGAAGCAAAGAGAGATCAGTAAAACCACTGGAAAAGAAAAGATGGAGAAAATGTTGGAAAACCAGAACTC
TCTGCTGTCAAGTTCATCTGGAATGTTCAAGAAAGAATCTGACTCTATTATTTAATATCTTACATACCTCCACCAGACTGGACTTGCTTT
TTGAATTTTAAGCAAGTTTCCTTTCCTTTTATACAAATTGCAAATTTCATATTTTTTTAATCACATCCTAGGAATAGCACAATAATTGGG
AAATAGAACCCTTATCACTAGAAGAACCATTTTCTGCCACTAAATATCTCTGATGTTTCCATGAGTCTGAGGGCAGAGACTCTGGTATAT
GAAAACGTCTGAAAGTCACATATTGTGAAAATTTGAAGCTATCTCAGTAAAAAGCAGCTTTGGAAACTGTGAATGATCTTTAGCTTGTAC
AAATGTTTAAAAATACCTCAGGCTATACTGAAAGGGTTGCAGTTTGGTTAGGAGTGGAAATATTTTGTTTGTTAATGATGTCTTCAGTTC
TGGTACCTCTGTTTTACTTTCTTATGCTCTTTGGAAACTTTTTGCAAAATTTAAGCCTGGGTTCTAGATAATACCAGATCTACCTAAACC
TCAAGTCTATGTTAAAGTTGCTTTCCTGCTGTTAAATAAGCTATGATATTAAGATATTCTGACTTGCTCCAGTGTCAAGGGACCTTCTGG
GAGCAGGTGCTAACATAGTGTTCAGAATCAATATGTGAGATGAAAAGGATCCCCTCCAGGAGGATCCTGAGCTGTTCAGAAATCATTTAA
GTTTACAGCGTTGTTCCCTTTGCGTTTGCAGTGCGTTTTACTCAAGTAGCCAGAAACACCCCACGTTTCTGAATTTGTTTAAACTGTAAC
AATAAAGTAAAATAGAATGCATGAAAGATATTCTGGCGATTGTAACTTAGAATTTTTCTGACTTCTGGATTTGTTGGCACTAGAACCTGA
TATTTAAAGTCTTACTGAGCAGCTATCAAGTGGCAGTTACAGGCACAAATTGGTGGAGGCTGGAGGATGGGGAGGGGAGCAAAACCCTTT
ATATTTGTGAAGAAAATATCTGTAGCTGATAGAAATAATTGCTTAAATTGGTTTATGAAATTAATGAGTCTGAAAAGGTTAAAAGCACTT
ATAAAAAGAACCAAGTCCTACATTTCCAGAACTTTCTGGCAAAAATTTGCACTCATATTATTTATCCTATGAACATTCCCATTGTTTTTT
TTTGCTATTTATATACAGATTATCATAAGAAAGCTCTCAGTTTGAGGACCCAAAATAAAACCAAAGTCATGCCATGACCCATACTCATTT
ACAAAAACAAGAACACTTTCCTCTATCCCTAAAATTATGCTTTAGTACTTGAGGCCTTTAAAAGTTAGTGCTTTTGATTGTGAAGACATT
CAGCAACTTACTTTGTCATACATGCAGTTGCACCTTACCACTTCTAATAGTGTCATATTTCATATTCAGGGGACTTAGATAATTTGCCTG
TGGATGGTTCTTTTGCAGGAAAAAAAATCTACATTTTGACCATACTACCCTTTCATGTCCTTATTATAAGCTTTTAGAAAATGATTTCAT
TCAGTCATGTCCAGTTATATAAAACGTTACTTTCTCATTTTTGAGAAGTTCAACAAAACATACTACTAAGACCAATCATCAAACCCACTA
TTATAAATGTTAATTTTGGCTGGGTAAGGTGGCTTGCGCCTATAATCCCAGCACTTTGGGAGGCTGAGGAGGGAAGATTGCTTGAGCCCA
GGAGTTTGAGACCAGCCTGGGCAACATAGCAAGATCCTGTCTCTACTAAAAATAAAAAAAAAAATTAGGCCAAGCATAGTGGCTCATGCC
TGTAATCCTAGCACTTTGGTAGTCCAAGGCAGGGGGATCACTTGAGCCCAGAAGTTCAAGACCAGCTTGGGTAACATAATGAGACCCTGT
GTCTACAAAAAATTTAAAAATTAGCCAGGCATGATGGTGCCCACCTGTAGCCCCAGCTACTCAGAGGCTGAGGTAGTGGAAGGATTGCTT
GAGCCTTGAGATGGAGGCTGCAGTGAGCTATGCCACTGTACTCTAGCCTGTTCAACTGAGCAGAACCCTGTCTGTAAAAGAAAATCAAAA
ACAAAAAATAAATGTTAAATTTTGTTTTAAGTTTTAGCACAGACTCCCCTCAAAACACCTTCTCCCCAATTTTACAGAAAGTAATTTAAA
AATGAAAACTTTACTCTGTAAAGACCTCTACAGTGTTTTTCTTTTCAAAATTTGGCTGATTTTAGGAAAAAAGTGATCATCTGAAACTAA
AAGAAATTGCTTGGTTAGTTTCCATATTAAAACAGCAGTGACAAGTATATATAACTTAGATCTCAGCATATGTGTTTGTATATTAAACTT
CACATATGTAGTTTTCAGTTTAATGGAATGAATCAAACTGGATCTATAACACTGAAAAAGTTCTATTGTAATAGACTCATACGGAGAATA
CTCTGCTATAATAATATAAAATTAAGAAGAAAAAGTATAAACGTAAGATGCTAAATTCCATAAATGCATATTTAGTACTATGTTTTTTGT
GGGAAAAGTTCTAAAAGTTTAAAATGCACAAAGAAAATGAAAAATACTAATATAAAAATTTGTGCTTTAATCTAGTCAAACTAAATCCTT
TCTAATTTCTGAATGAAGTGTTACTGCTGCAATAAAGTGACCTGATAAGCCTAAATTTTTTGTGTTCAATCCAGACACTTTTCTGAGAGT
CTGAAAAGAATACAGAGTCAGAACTCTGTTTTTATCTCCTCATCCTGTTTTTGATAAGACTCAGAAAATTCTCAAATTCGAAAGGTTCTG
GCATTTGAGGCCAAAAAAAGCATGAAAGGGAGTAACATTCCTTTTTATAGATACTCTAGATTGGATACTATTGTAACAGATGGCCAAGAA
ACTTCCAGAAACATTTTGGTTAAATTTTATTGCAATGGATATTGCTGGGATCCATCCATTTAAGCAGTAATATACCACCCAGATTATTGA
TACTTTATGCAAGATGTGTTCATCTCTTTGATCATATTTACAATGCTTACTCCATAGCCCTGCTACAAGACTTAAAATTTCCACTGAAAA
TTGCATAGTTCTTGTATTAAGATTCAAATTCTGGCTGGGCGCAGTGGCTCACGCTTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCG
GATTGCCTGAGCTCAGGAGTTCGCAACCAGCCTGGGAAACACGGTGAAGCTCCATCTCTACTAAAATACAAAAAAATTAGCCAGGCGTGT
CGGCATGCACCTGTAGTCCCAGCTACTCGGGAAGCTGAGGCAGGAGAAGAATCCAGGAGGCAGAGGTTGCAGTGAGGCGAGATTGCGCCA
CTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGTAAAAGTACACACAGTTTAAAAGTAAACATGTT
TACTTCGGATAATTCTAATCCTTTTAGCTGCATTTAAGAATATTTTAATTTATACGAATGTTACTTGAAATTGGCCTATGTCCAGATGAC
TTTTGATGTTAAATCAATGGAAAACTGAATAGAAAATATGACACGAGATCGGGGAGGGGGAAGGCAACCTATAGCATGGGTGGCTCTGAG
GAGTTCCTGCTGGTGCACTTTCATGCCCTTTCTTATGTACCTTTTGTCTTACTCTTCTTACATTATTCTTATCCTCATCATTTTTTCATT
TCCCTTTACTTCCTCCTATCCTTCAAAAACCTCCTGAAGAGTCCATTAACATCCATGCTTAGTTCCACTGGTTGCATGGCTGTATTTCCT
ACTGATCCCTGTAGTTTCACTGAATGGATCCCCACCCAATTTCGTGTATCCTGGTGAATGGCTTTCTCTCAGCCTTCGACTTAGTTCTAA
TGATCTACATTGAATTTAAATTACATGACTGAAATATTTAAGGGAAGAAATAAATTTCATACAAATTAGTATCTTTTATGCTAACATTTA
AAACTGTATTTAAATTTTTAAGGTAAATGCTTTGGGGAAAAAAAAAACCATTGCCAAGTCTTTAGCATATTTTCAGAGAGCGTAATTTTT
TACTTTGATTTCCAGTTTCACTAAGGTTTCATTAAATCTTAGTTCCGAGAGCCCAGCATGAAGGGTGACTGGGAATGTAGTGTGCCTCTC
TGATGCAGTTCCTAATGATTGTTCTTCAGGGACCTTCCTTAGGTTAGGTTACATTTTCTGGTGAATGGTGTTAGAGTAAATTCCCAGAGT
TTAGAGATACAAGTAGAAATGCATAAGCTAATTAGCTCCAATTTTATAATATGTAAACAATTTAAACAAGTATTTAAAACTTTTTAGGAA
GTCTCTAACACTGAAAAAAAGGTCATTGTTGCTGGTATAAACATTAAGGAGCAACTTTTACATTAGGTCAAAGATTGTTGCTTTTCCAGT
GTGTTGTCTTAAAAATAGAAGGAAATAAAACTATTACCTTCTTTTTACATCTATATGTTTTTATAATTTGAAAGGCAAGTAGTATCTTGG
TGAATAAGAAATGCATCATCCATAACAATTTAATTAACTCTTAAAAAGACCAGCTTTTTGTCTTGTTATGAAAACAAAACGCAATTTGTC
ATTCATAATGGTAATGTGGAATAAGAATACATCGTAGAAGGAAGACTTGCTACTTTACTGACTTAATCATTAGTTCTAAGGCCATGTGTG
GCGGCTCACGCCTGTAATCCCAGCACTTTGGGAGTCCAAGGCGGTAGGATCACCAGAGCCCAGGGTTCAAGACTCAGCCTGGGCAACATA
GTGAGATTTCGTCTCTACAAAAAAAATTTAGCCAGCTTGGTGGCACATGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAAGAGGATT
GCTTGAGCATAGCAGGTCAAGTCTGCAGTGAGCTGTGGTTGCACCACTGCACTCCAGCCTGGGTGACAAAATGAGACCTTGTCTACAAAA
AGGAAAAAAAAATTTGTTCTGCTCTACTATACATGCTGACTTTTGTTGATAGCTTGGTCTAAAAAGACTGTCTAGAGCTGAATTTAAGAA
TGGTTCTGGAGCAAATAATAACAAGGTAGACAAGCAGGCCCTGGGCTCACTATAATTTCATAGCCACGACCTGTTTATTATTAGTTGGCA
GAGATTAATGCTTTGTGTTATAAATATACTATAGAACAATAGGTCACGATTCTCAAGAACAAAGCCGAATGCTCGCAGTTAAGTGTGAAG
CTTGCATAAGTGTCGGAACCACAATTATGGACCCACCATCAATGTGCATTTTATCAGATGACTCCTCCTGAGACAGTAAAGACTCCTGGA
AAATTCATGACATCTTTGAATCACTCAGAAAAATCTTGAAACTCAGGACGTAGTTTACTTAGCTTGCCTTTTTTAAAATTATCAAATTTT
AAATCGTAAACTTTGTCTTCACTTCCACACGTTCAAGGACACCTCTTTTAAAGTTCAGTGTTCCATACTAAAGGGGTGTAATCTTGCTTT
CTGGGGAAATAAAATTCCCCATGGTACTATATTCCTGACAGATATAAAATAACATGAGGCTACCTCATTTTTGAAATAGATTTCAATATT
TTTATTAGTAAGTTGGAAAGACAGTAGGAACAAAATGAAACCTTTCTAAGTACTTGATGACACCCACTTGATCATGACAATTCATCTACC
TCCGCTTTCCGTGTCCAGCTGAAAGCCCAGCTGAGTCAACTCCTGCTTCATCAGAAGGGAGCTAATGGTGATTCTGGGATTAAAAAGCAA
GGGGGGTGCAAATTGTTAGTGGGGTCAAAATATCAGTAAAATTTCTTAAGTGCTTTGTTCTGATAAACGGATGTAAAAGTAACAAAAAAG
GAATAACAACTAATATGGCCTGTGGATCTGACAAAGAAAAACCTGAAGAAATTCAGAATCTAGATACACTTAGATTCTAAATTAGACACA
CTCAGATTCTAATGAACACTTAGAATGCTTCGCCAGTGGCTTTTCAAGTTACACTGGAAGCTTGATTATGAAAAAGTTTTGTTTTCATTG
GCAAGAGGGTAGATGATCAGTGATGACAGATTGTACAGCTGTGCCCAAACCTGACAACTTACACATTAAACTCCTGTAAGAGACACTCCT
TCCTAGTAGAACAAGGACTGGGACAATGAATTTTTGACTCACTGGAGTTTTTTAAAATGCTGTTCTTGAGTGTGGCAATAGTGTAGGAGT
TAACCCAGTCTACCCAAAGAAGTTGCTTTGCCTTTCAATATGAGTGCTATAAAAAGAGTATTTTGGAGTTCAATGTCCCTAAACATGTAT
GCGATAGGAACTACCAATATAAAATAACACTTAGAACTCAAATTAGATTGGTAATACTATTTTGGAGCCTGTGATGTATGACTTTTATTC
TTTACTAGATATTTTTCAGTATCCGTCATTAGAAGAGTCAGTTTGTTAAATATTTTAAATGTGTAAACACAAAACCTTTCTACTGTGATC
TTCCCTAATGAGTCAAAGTATCTTTCATAATTCAGTCTATATTGAAATGTTATTTCAGGAATGGAGGGTTTGTTATTAATAGTGCTGGGC
CGGGCACGGTGACTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGACAGGCGAATCACCTGAGGTCAGATGTTGGAGACCAGCCTGA
CCAACATGGAGAAACCCCATCTCTACCAAAAATACAAAATTAGCCGGGCGTGGTGGCTCCATGCTGTAATCCCAGCTACTCGGGAGGCTG
AGGCAGGAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATTGCACCATAGCACTCCAGCCTGGGCAACAAGAGCAAAA
CTCTGTCTCAAAAAAAAAAAAAAAAAAAATAGTGCTGCATTTTGACCCTGGACTATGAACAGACTGTATAGTTGGTGCCTCTTTTTTTTC
TACCAAAGATTATTAGATCAAGATTGGTGCTATACTTCATGTTCCTTTCAAAATTATTTTTCTTTTAAAAATATTAATATACAACACAAT
AGAAAATGTATACAGCCAGCAACGTTATGCATGTTGCATGTTATATACATGACTGAGGAAAAAAGCTCACCTATACAGTGATTATTGAGT
TCCAGTATCTAGTTAGAGGTATGCAATTTTTGTTAACATATAAGACTTTAAATTACGAAACTCACAAGAAAATGATCACCAAATGAGAAT
GTTCTAATGAACACAACCTCCCAAGGTAATAATTTTAAAGAAAAAGTCCCTTGTCAATGTTTCTAGCACAAAGTGAGGGATTTAAATATA
TTCTGTAACTTTGAGGCAATGTGAAAAAGTTATATATAATAGCTTCCTATTGAGCTGGCTTATGTAGACATTTGGACATTTGAAACTATT
TCGCAACTTTCAGGCTAAAATCAGAGTTTTGAGAGTCATCAATCTTAAAACATGGATAATGAGTTATTTGCACAGTTATATTTTTATAAT
TATTTGAAATTTATCACTGAAAGTATCATTGTTTGTCTTTCAGATTTAACATAAACAATAAGTACTGCGGCTGGGTCACTGTCAGCAAAT
CTCAGGTCTATGATTTATCAAGGGCTCTCAGCACCATCGTTGGTCTGATTGTGTAACACCTAAGTAAAATAACATATGGGTCTCCTTGGC
CAGGCGCCGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCGGATTGCTTGAGGCCAGGAGTTCGAGACATACGGGT
CTCTTTAATGTTCTGTAGGTAGGATTCAGATGAATTGAGAATGACAGGTTTCTTTTTCTTTCTTTGTTTCTTTTTTTTTTTTTTTTTTGA
GATGGAGTCTTGCTCTATTGCCAGGCTCCATATAGTGGCGCGATCTCAGCTCACTGCAACCTCCGCCTCCCGGGCTCAAGTGATTCTCGT
GCCTCAGTCTTCTGAGTAGCTGGGACTACAGGTGCCCACTACCACACCGGCTAATTTTTGTATTTTTGGTAGAGATGGAGTTTCACCATG
TTGGCCAGACTGGCCTTAAGTGATCCACCTGCCTCAGCCTCCCCAAGTGCTGGAATTACAGGCATGAGCCACCATGCCCGGCTAGAGAAT
GACAGGTTTCAGTTGAATTCTTCTCTTTTAAAAGACCCTGACTTAACTGTATTTTATGAGGATTTTATAAATGTAAATTAAGAAGACAAT
ACACACTCTCATTTTCCTAATTAGAAAGACTATGCATTCACAATCCAGTACACTGGATTTGCTCTGGTAACTAATGATAACACTTTTCTA
CGTTAACATGAGTTATATTTGGCAGAGAGAATGGAAGCTTGCTAATCAGAAGTTACATTAGGGTGAGATTAAACATCACTCTAATAATAA
CTTCTGATGTAACTTAATGTGGTTTGAGATGTGTAAGATTGTAGAGGCATTGCACAATGCTTGATAAAAGTTGCATTTTGCTTTTGTTCT
TCCACCAGTTTATTTTAGCCTTAAAGTTATAGCTACAACAAATTGAACCCTGTAGTTATTACTGAAAGAGAGTGTGGATATTTTAAGTAT
CTCCTAGTATAATATGACATTGTTCATGTGGACTTATTTTAATGTTTATTTGAAAATTAATTTTTTAATTATTTTGTATATTTTGAGTTA
GAAAAACACACTTTATCTTAGACACCAAAGCCAAATTATTCCAAGTGTATGCTATACACCGCAGTGCAGCTCTGCTTCTCTCCCAACCTA
CCCTGGGGCCATTTTTGGCACAATAGTTGTTCAAATGTAGATCACTATGCTGAATGCTCATGCTGGATTTGACCAGTATGCAGTATTTTA
GTACTTTTTAAAAAATGTATGCTTCTTTTTGAAGACTATAATTTACAATTTTTTTAATAATGTGCAATTTAATATAGATAACCAAAATCT
TTTTAATGAAAAGATCTTTACAATTGCTTGGAGGATAAGATTATTTTACTGTGGAAAAATGTGATACTCTTAGTAAATGCAATAAAAACT

>94291_94291_1_TRMT11-SLC16A10_TRMT11_chr6_126314968_ENST00000334379_SLC16A10_chr6_111527795_ENST00000368850_length(amino acids)=274AA_BP=73
MSLWRLGFGREKEGPSAGRAGARWAAAMALSCTLNRYLLLMAQEHLEFRLPEIKSLLLLFGGQFASSQETYGKMKHVNERFQDEKNKEVV
LMCIGVTSGVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFELVGAQDVSQAIG
FLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIPWIHSKKQREISKTTGKEKMEKMLENQNSLLSSSSGMFKKES

--------------------------------------------------------------
>94291_94291_2_TRMT11-SLC16A10_TRMT11_chr6_126314968_ENST00000334379_SLC16A10_chr6_111527795_ENST00000368851_length(transcript)=1650nt_BP=259nt
CGCCTGCCTCGCAGAGCTTCCGCTTCCGGCCCTTCAGGCTCTGTCTCTGTGGAGACTGGGCTTTGGGAGGGAGAAAGAGGGACCTAGCGC
GGGCCGCGCAGGCGCACGGTGGGCAGCTGCAATGGCGCTGTCGTGTACCCTTAACAGGTATCTGCTCCTCATGGCGCAGGAGCATCTGGA
GTTCCGCCTGCCGGAAATAAAGTCTTTGCTTTTGCTTTTTGGAGGTCAGTTTGCCAGCAGTCAAGAAACTTATGGAAAGATGAAACATGT
AAATGAAAGATTTCAAGATGAAAAAAATAAAGAGGTTGTTCTCATGTGCATTGGCGTCACTTCAGGAGTTGGACGACTGCTCTTTGGCCG
GATTGCAGATTATGTGCCTGGTGTGAAGAAGGTTTATCTACAGGTACTCTCCTTTTTCTTCATTGGTCTGATGTCCATGATGATTCCTCT
GTGTAGCATCTTTGGGGCCCTCATTGCTGTGTGCCTCATCATGGGTCTCTTCGATGGATGCTTCATTTCCATTATGGCTCCCATAGCCTT
TGAGTTAGTTGGTGCCCAGGATGTCTCCCAAGCAATTGGATTTCTGCTCGGATTCATGTCTATACCCATGACTGTTGGCCCACCCATTGC
AGGGTTACTTCGTGACAAACTGGGCTCCTATGATGTGGCATTCTACCTCGCTGGAGTCCCTCCCCTTATTGGAGGTGCTGTGCTTTGTTT
TATCCCGTGGATCCATAGTAAGAAGCAAAGAGAGATCAGTAAAACCACTGGAAAAGAAAAGATGGAGAAAATGTTGGAAAACCAGAACTC
TCTGCTGTCAAGTTCATCTGGAATGTTCAAGAAAGAATCTGACTCTATTATTTAATATCTTACATACCTCCACCAGACTGGACTTGCTTT
TTGAATTTTAAGCAAGTTTCCTTTCCTTTTATACAAATTGCAAATTTCATATTTTTTTAATCACATCCTAGGAATAGCACAATAATTGGG
AAATAGAACCCTTATCACTAGAAGAACCATTTTCTGCCACTAAATATCTCTGATGTTTCCATGAGTCTGAGGGCAGAGACTCTGGTATAT
GAAAACGTCTGAAAGTCACATATTGTGAAAATTTGAAGCTATCTCAGTAAAAAGCAGCTTTGGAAACTGTGAATGATCTTTAGCTTGTAC
AAATGTTTAAAAATACCTCAGGCTATACTGAAAGGGTTGCAGTTTGGTTAGGAGTGGAAATATTTTGTTTGTTAATGATGTCTTCAGTTC
TGGTACCTCTGTTTTACTTTCTTATGCTCTTTGGAAACTTTTTGCAAAATTTAAGCCTGGGTTCTAGATAATACCAGATCTACCTAAACC
TCAAGTCTATGTTAAAGTTGCTTTCCTGCTGTTAAATAAGCTATGATATTAAGATATTCTGACTTGCTCCAGTGTCAAGGGACCTTCTGG
GAGCAGGTGCTAACATAGTGTTCAGAATCAATATGTGAGATGAAAAGGATCCCCTCCAGGAGGATCCTGAGCTGTTCAGAAATCATTTAA
GTTTACAGCGTTGTTCCCTTTGCGTTTGCAGTGCGTTTTACTCAAGTAGCCAGAAACACCCCACGTTTCTGAATTTGTTTAAACTGTAAC

>94291_94291_2_TRMT11-SLC16A10_TRMT11_chr6_126314968_ENST00000334379_SLC16A10_chr6_111527795_ENST00000368851_length(amino acids)=274AA_BP=73
MSLWRLGFGREKEGPSAGRAGARWAAAMALSCTLNRYLLLMAQEHLEFRLPEIKSLLLLFGGQFASSQETYGKMKHVNERFQDEKNKEVV
LMCIGVTSGVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFELVGAQDVSQAIG
FLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIPWIHSKKQREISKTTGKEKMEKMLENQNSLLSSSSGMFKKES

--------------------------------------------------------------
>94291_94291_3_TRMT11-SLC16A10_TRMT11_chr6_126314968_ENST00000368332_SLC16A10_chr6_111527795_ENST00000368850_length(transcript)=9775nt_BP=210nt
TGGAGACTGGGCTTTGGGAGGGAGAAAGAGGGACCTAGCGCGGGCCGCGCAGGCGCACGGTGGGCAGCTGCAATGGCGCTGTCGTGTACC
CTTAACAGGTATCTGCTCCTCATGGCGCAGGAGCATCTGGAGTTCCGCCTGCCGGAAATAAAGTCTTTGCTTTTGCTTTTTGGAGGTCAG
TTTGCCAGCAGTCAAGAAACTTATGGAAAGATGAAACATGTAAATGAAAGATTTCAAGATGAAAAAAATAAAGAGGTTGTTCTCATGTGC
ATTGGCGTCACTTCAGGAGTTGGACGACTGCTCTTTGGCCGGATTGCAGATTATGTGCCTGGTGTGAAGAAGGTTTATCTACAGGTACTC
TCCTTTTTCTTCATTGGTCTGATGTCCATGATGATTCCTCTGTGTAGCATCTTTGGGGCCCTCATTGCTGTGTGCCTCATCATGGGTCTC
TTCGATGGATGCTTCATTTCCATTATGGCTCCCATAGCCTTTGAGTTAGTTGGTGCCCAGGATGTCTCCCAAGCAATTGGATTTCTGCTC
GGATTCATGTCTATACCCATGACTGTTGGCCCACCCATTGCAGGGTTACTTCGTGACAAACTGGGCTCCTATGATGTGGCATTCTACCTC
GCTGGAGTCCCTCCCCTTATTGGAGGTGCTGTGCTTTGTTTTATCCCGTGGATCCATAGTAAGAAGCAAAGAGAGATCAGTAAAACCACT
GGAAAAGAAAAGATGGAGAAAATGTTGGAAAACCAGAACTCTCTGCTGTCAAGTTCATCTGGAATGTTCAAGAAAGAATCTGACTCTATT
ATTTAATATCTTACATACCTCCACCAGACTGGACTTGCTTTTTGAATTTTAAGCAAGTTTCCTTTCCTTTTATACAAATTGCAAATTTCA
TATTTTTTTAATCACATCCTAGGAATAGCACAATAATTGGGAAATAGAACCCTTATCACTAGAAGAACCATTTTCTGCCACTAAATATCT
CTGATGTTTCCATGAGTCTGAGGGCAGAGACTCTGGTATATGAAAACGTCTGAAAGTCACATATTGTGAAAATTTGAAGCTATCTCAGTA
AAAAGCAGCTTTGGAAACTGTGAATGATCTTTAGCTTGTACAAATGTTTAAAAATACCTCAGGCTATACTGAAAGGGTTGCAGTTTGGTT
AGGAGTGGAAATATTTTGTTTGTTAATGATGTCTTCAGTTCTGGTACCTCTGTTTTACTTTCTTATGCTCTTTGGAAACTTTTTGCAAAA
TTTAAGCCTGGGTTCTAGATAATACCAGATCTACCTAAACCTCAAGTCTATGTTAAAGTTGCTTTCCTGCTGTTAAATAAGCTATGATAT
TAAGATATTCTGACTTGCTCCAGTGTCAAGGGACCTTCTGGGAGCAGGTGCTAACATAGTGTTCAGAATCAATATGTGAGATGAAAAGGA
TCCCCTCCAGGAGGATCCTGAGCTGTTCAGAAATCATTTAAGTTTACAGCGTTGTTCCCTTTGCGTTTGCAGTGCGTTTTACTCAAGTAG
CCAGAAACACCCCACGTTTCTGAATTTGTTTAAACTGTAACAATAAAGTAAAATAGAATGCATGAAAGATATTCTGGCGATTGTAACTTA
GAATTTTTCTGACTTCTGGATTTGTTGGCACTAGAACCTGATATTTAAAGTCTTACTGAGCAGCTATCAAGTGGCAGTTACAGGCACAAA
TTGGTGGAGGCTGGAGGATGGGGAGGGGAGCAAAACCCTTTATATTTGTGAAGAAAATATCTGTAGCTGATAGAAATAATTGCTTAAATT
GGTTTATGAAATTAATGAGTCTGAAAAGGTTAAAAGCACTTATAAAAAGAACCAAGTCCTACATTTCCAGAACTTTCTGGCAAAAATTTG
CACTCATATTATTTATCCTATGAACATTCCCATTGTTTTTTTTTGCTATTTATATACAGATTATCATAAGAAAGCTCTCAGTTTGAGGAC
CCAAAATAAAACCAAAGTCATGCCATGACCCATACTCATTTACAAAAACAAGAACACTTTCCTCTATCCCTAAAATTATGCTTTAGTACT
TGAGGCCTTTAAAAGTTAGTGCTTTTGATTGTGAAGACATTCAGCAACTTACTTTGTCATACATGCAGTTGCACCTTACCACTTCTAATA
GTGTCATATTTCATATTCAGGGGACTTAGATAATTTGCCTGTGGATGGTTCTTTTGCAGGAAAAAAAATCTACATTTTGACCATACTACC
CTTTCATGTCCTTATTATAAGCTTTTAGAAAATGATTTCATTCAGTCATGTCCAGTTATATAAAACGTTACTTTCTCATTTTTGAGAAGT
TCAACAAAACATACTACTAAGACCAATCATCAAACCCACTATTATAAATGTTAATTTTGGCTGGGTAAGGTGGCTTGCGCCTATAATCCC
AGCACTTTGGGAGGCTGAGGAGGGAAGATTGCTTGAGCCCAGGAGTTTGAGACCAGCCTGGGCAACATAGCAAGATCCTGTCTCTACTAA
AAATAAAAAAAAAAATTAGGCCAAGCATAGTGGCTCATGCCTGTAATCCTAGCACTTTGGTAGTCCAAGGCAGGGGGATCACTTGAGCCC
AGAAGTTCAAGACCAGCTTGGGTAACATAATGAGACCCTGTGTCTACAAAAAATTTAAAAATTAGCCAGGCATGATGGTGCCCACCTGTA
GCCCCAGCTACTCAGAGGCTGAGGTAGTGGAAGGATTGCTTGAGCCTTGAGATGGAGGCTGCAGTGAGCTATGCCACTGTACTCTAGCCT
GTTCAACTGAGCAGAACCCTGTCTGTAAAAGAAAATCAAAAACAAAAAATAAATGTTAAATTTTGTTTTAAGTTTTAGCACAGACTCCCC
TCAAAACACCTTCTCCCCAATTTTACAGAAAGTAATTTAAAAATGAAAACTTTACTCTGTAAAGACCTCTACAGTGTTTTTCTTTTCAAA
ATTTGGCTGATTTTAGGAAAAAAGTGATCATCTGAAACTAAAAGAAATTGCTTGGTTAGTTTCCATATTAAAACAGCAGTGACAAGTATA
TATAACTTAGATCTCAGCATATGTGTTTGTATATTAAACTTCACATATGTAGTTTTCAGTTTAATGGAATGAATCAAACTGGATCTATAA
CACTGAAAAAGTTCTATTGTAATAGACTCATACGGAGAATACTCTGCTATAATAATATAAAATTAAGAAGAAAAAGTATAAACGTAAGAT
GCTAAATTCCATAAATGCATATTTAGTACTATGTTTTTTGTGGGAAAAGTTCTAAAAGTTTAAAATGCACAAAGAAAATGAAAAATACTA
ATATAAAAATTTGTGCTTTAATCTAGTCAAACTAAATCCTTTCTAATTTCTGAATGAAGTGTTACTGCTGCAATAAAGTGACCTGATAAG
CCTAAATTTTTTGTGTTCAATCCAGACACTTTTCTGAGAGTCTGAAAAGAATACAGAGTCAGAACTCTGTTTTTATCTCCTCATCCTGTT
TTTGATAAGACTCAGAAAATTCTCAAATTCGAAAGGTTCTGGCATTTGAGGCCAAAAAAAGCATGAAAGGGAGTAACATTCCTTTTTATA
GATACTCTAGATTGGATACTATTGTAACAGATGGCCAAGAAACTTCCAGAAACATTTTGGTTAAATTTTATTGCAATGGATATTGCTGGG
ATCCATCCATTTAAGCAGTAATATACCACCCAGATTATTGATACTTTATGCAAGATGTGTTCATCTCTTTGATCATATTTACAATGCTTA
CTCCATAGCCCTGCTACAAGACTTAAAATTTCCACTGAAAATTGCATAGTTCTTGTATTAAGATTCAAATTCTGGCTGGGCGCAGTGGCT
CACGCTTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCGGATTGCCTGAGCTCAGGAGTTCGCAACCAGCCTGGGAAACACGGTGAAG
CTCCATCTCTACTAAAATACAAAAAAATTAGCCAGGCGTGTCGGCATGCACCTGTAGTCCCAGCTACTCGGGAAGCTGAGGCAGGAGAAG
AATCCAGGAGGCAGAGGTTGCAGTGAGGCGAGATTGCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCATCTCAAAAAAAAAA
AAAAAAAGTAAAAGTACACACAGTTTAAAAGTAAACATGTTTACTTCGGATAATTCTAATCCTTTTAGCTGCATTTAAGAATATTTTAAT
TTATACGAATGTTACTTGAAATTGGCCTATGTCCAGATGACTTTTGATGTTAAATCAATGGAAAACTGAATAGAAAATATGACACGAGAT
CGGGGAGGGGGAAGGCAACCTATAGCATGGGTGGCTCTGAGGAGTTCCTGCTGGTGCACTTTCATGCCCTTTCTTATGTACCTTTTGTCT
TACTCTTCTTACATTATTCTTATCCTCATCATTTTTTCATTTCCCTTTACTTCCTCCTATCCTTCAAAAACCTCCTGAAGAGTCCATTAA
CATCCATGCTTAGTTCCACTGGTTGCATGGCTGTATTTCCTACTGATCCCTGTAGTTTCACTGAATGGATCCCCACCCAATTTCGTGTAT
CCTGGTGAATGGCTTTCTCTCAGCCTTCGACTTAGTTCTAATGATCTACATTGAATTTAAATTACATGACTGAAATATTTAAGGGAAGAA
ATAAATTTCATACAAATTAGTATCTTTTATGCTAACATTTAAAACTGTATTTAAATTTTTAAGGTAAATGCTTTGGGGAAAAAAAAAACC
ATTGCCAAGTCTTTAGCATATTTTCAGAGAGCGTAATTTTTTACTTTGATTTCCAGTTTCACTAAGGTTTCATTAAATCTTAGTTCCGAG
AGCCCAGCATGAAGGGTGACTGGGAATGTAGTGTGCCTCTCTGATGCAGTTCCTAATGATTGTTCTTCAGGGACCTTCCTTAGGTTAGGT
TACATTTTCTGGTGAATGGTGTTAGAGTAAATTCCCAGAGTTTAGAGATACAAGTAGAAATGCATAAGCTAATTAGCTCCAATTTTATAA
TATGTAAACAATTTAAACAAGTATTTAAAACTTTTTAGGAAGTCTCTAACACTGAAAAAAAGGTCATTGTTGCTGGTATAAACATTAAGG
AGCAACTTTTACATTAGGTCAAAGATTGTTGCTTTTCCAGTGTGTTGTCTTAAAAATAGAAGGAAATAAAACTATTACCTTCTTTTTACA
TCTATATGTTTTTATAATTTGAAAGGCAAGTAGTATCTTGGTGAATAAGAAATGCATCATCCATAACAATTTAATTAACTCTTAAAAAGA
CCAGCTTTTTGTCTTGTTATGAAAACAAAACGCAATTTGTCATTCATAATGGTAATGTGGAATAAGAATACATCGTAGAAGGAAGACTTG
CTACTTTACTGACTTAATCATTAGTTCTAAGGCCATGTGTGGCGGCTCACGCCTGTAATCCCAGCACTTTGGGAGTCCAAGGCGGTAGGA
TCACCAGAGCCCAGGGTTCAAGACTCAGCCTGGGCAACATAGTGAGATTTCGTCTCTACAAAAAAAATTTAGCCAGCTTGGTGGCACATG
CCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAAGAGGATTGCTTGAGCATAGCAGGTCAAGTCTGCAGTGAGCTGTGGTTGCACCACTG
CACTCCAGCCTGGGTGACAAAATGAGACCTTGTCTACAAAAAGGAAAAAAAAATTTGTTCTGCTCTACTATACATGCTGACTTTTGTTGA
TAGCTTGGTCTAAAAAGACTGTCTAGAGCTGAATTTAAGAATGGTTCTGGAGCAAATAATAACAAGGTAGACAAGCAGGCCCTGGGCTCA
CTATAATTTCATAGCCACGACCTGTTTATTATTAGTTGGCAGAGATTAATGCTTTGTGTTATAAATATACTATAGAACAATAGGTCACGA
TTCTCAAGAACAAAGCCGAATGCTCGCAGTTAAGTGTGAAGCTTGCATAAGTGTCGGAACCACAATTATGGACCCACCATCAATGTGCAT
TTTATCAGATGACTCCTCCTGAGACAGTAAAGACTCCTGGAAAATTCATGACATCTTTGAATCACTCAGAAAAATCTTGAAACTCAGGAC
GTAGTTTACTTAGCTTGCCTTTTTTAAAATTATCAAATTTTAAATCGTAAACTTTGTCTTCACTTCCACACGTTCAAGGACACCTCTTTT
AAAGTTCAGTGTTCCATACTAAAGGGGTGTAATCTTGCTTTCTGGGGAAATAAAATTCCCCATGGTACTATATTCCTGACAGATATAAAA
TAACATGAGGCTACCTCATTTTTGAAATAGATTTCAATATTTTTATTAGTAAGTTGGAAAGACAGTAGGAACAAAATGAAACCTTTCTAA
GTACTTGATGACACCCACTTGATCATGACAATTCATCTACCTCCGCTTTCCGTGTCCAGCTGAAAGCCCAGCTGAGTCAACTCCTGCTTC
ATCAGAAGGGAGCTAATGGTGATTCTGGGATTAAAAAGCAAGGGGGGTGCAAATTGTTAGTGGGGTCAAAATATCAGTAAAATTTCTTAA
GTGCTTTGTTCTGATAAACGGATGTAAAAGTAACAAAAAAGGAATAACAACTAATATGGCCTGTGGATCTGACAAAGAAAAACCTGAAGA
AATTCAGAATCTAGATACACTTAGATTCTAAATTAGACACACTCAGATTCTAATGAACACTTAGAATGCTTCGCCAGTGGCTTTTCAAGT
TACACTGGAAGCTTGATTATGAAAAAGTTTTGTTTTCATTGGCAAGAGGGTAGATGATCAGTGATGACAGATTGTACAGCTGTGCCCAAA
CCTGACAACTTACACATTAAACTCCTGTAAGAGACACTCCTTCCTAGTAGAACAAGGACTGGGACAATGAATTTTTGACTCACTGGAGTT
TTTTAAAATGCTGTTCTTGAGTGTGGCAATAGTGTAGGAGTTAACCCAGTCTACCCAAAGAAGTTGCTTTGCCTTTCAATATGAGTGCTA
TAAAAAGAGTATTTTGGAGTTCAATGTCCCTAAACATGTATGCGATAGGAACTACCAATATAAAATAACACTTAGAACTCAAATTAGATT
GGTAATACTATTTTGGAGCCTGTGATGTATGACTTTTATTCTTTACTAGATATTTTTCAGTATCCGTCATTAGAAGAGTCAGTTTGTTAA
ATATTTTAAATGTGTAAACACAAAACCTTTCTACTGTGATCTTCCCTAATGAGTCAAAGTATCTTTCATAATTCAGTCTATATTGAAATG
TTATTTCAGGAATGGAGGGTTTGTTATTAATAGTGCTGGGCCGGGCACGGTGACTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGA
CAGGCGAATCACCTGAGGTCAGATGTTGGAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACCAAAAATACAAAATTAGCCGGGC
GTGGTGGCTCCATGCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAA
GATTGCACCATAGCACTCCAGCCTGGGCAACAAGAGCAAAACTCTGTCTCAAAAAAAAAAAAAAAAAAAATAGTGCTGCATTTTGACCCT
GGACTATGAACAGACTGTATAGTTGGTGCCTCTTTTTTTTCTACCAAAGATTATTAGATCAAGATTGGTGCTATACTTCATGTTCCTTTC
AAAATTATTTTTCTTTTAAAAATATTAATATACAACACAATAGAAAATGTATACAGCCAGCAACGTTATGCATGTTGCATGTTATATACA
TGACTGAGGAAAAAAGCTCACCTATACAGTGATTATTGAGTTCCAGTATCTAGTTAGAGGTATGCAATTTTTGTTAACATATAAGACTTT
AAATTACGAAACTCACAAGAAAATGATCACCAAATGAGAATGTTCTAATGAACACAACCTCCCAAGGTAATAATTTTAAAGAAAAAGTCC
CTTGTCAATGTTTCTAGCACAAAGTGAGGGATTTAAATATATTCTGTAACTTTGAGGCAATGTGAAAAAGTTATATATAATAGCTTCCTA
TTGAGCTGGCTTATGTAGACATTTGGACATTTGAAACTATTTCGCAACTTTCAGGCTAAAATCAGAGTTTTGAGAGTCATCAATCTTAAA
ACATGGATAATGAGTTATTTGCACAGTTATATTTTTATAATTATTTGAAATTTATCACTGAAAGTATCATTGTTTGTCTTTCAGATTTAA
CATAAACAATAAGTACTGCGGCTGGGTCACTGTCAGCAAATCTCAGGTCTATGATTTATCAAGGGCTCTCAGCACCATCGTTGGTCTGAT
TGTGTAACACCTAAGTAAAATAACATATGGGTCTCCTTGGCCAGGCGCCGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGG
CAGGCGGATTGCTTGAGGCCAGGAGTTCGAGACATACGGGTCTCTTTAATGTTCTGTAGGTAGGATTCAGATGAATTGAGAATGACAGGT
TTCTTTTTCTTTCTTTGTTTCTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTATTGCCAGGCTCCATATAGTGGCGCGATCTCAG
CTCACTGCAACCTCCGCCTCCCGGGCTCAAGTGATTCTCGTGCCTCAGTCTTCTGAGTAGCTGGGACTACAGGTGCCCACTACCACACCG
GCTAATTTTTGTATTTTTGGTAGAGATGGAGTTTCACCATGTTGGCCAGACTGGCCTTAAGTGATCCACCTGCCTCAGCCTCCCCAAGTG
CTGGAATTACAGGCATGAGCCACCATGCCCGGCTAGAGAATGACAGGTTTCAGTTGAATTCTTCTCTTTTAAAAGACCCTGACTTAACTG
TATTTTATGAGGATTTTATAAATGTAAATTAAGAAGACAATACACACTCTCATTTTCCTAATTAGAAAGACTATGCATTCACAATCCAGT
ACACTGGATTTGCTCTGGTAACTAATGATAACACTTTTCTACGTTAACATGAGTTATATTTGGCAGAGAGAATGGAAGCTTGCTAATCAG
AAGTTACATTAGGGTGAGATTAAACATCACTCTAATAATAACTTCTGATGTAACTTAATGTGGTTTGAGATGTGTAAGATTGTAGAGGCA
TTGCACAATGCTTGATAAAAGTTGCATTTTGCTTTTGTTCTTCCACCAGTTTATTTTAGCCTTAAAGTTATAGCTACAACAAATTGAACC
CTGTAGTTATTACTGAAAGAGAGTGTGGATATTTTAAGTATCTCCTAGTATAATATGACATTGTTCATGTGGACTTATTTTAATGTTTAT
TTGAAAATTAATTTTTTAATTATTTTGTATATTTTGAGTTAGAAAAACACACTTTATCTTAGACACCAAAGCCAAATTATTCCAAGTGTA
TGCTATACACCGCAGTGCAGCTCTGCTTCTCTCCCAACCTACCCTGGGGCCATTTTTGGCACAATAGTTGTTCAAATGTAGATCACTATG
CTGAATGCTCATGCTGGATTTGACCAGTATGCAGTATTTTAGTACTTTTTAAAAAATGTATGCTTCTTTTTGAAGACTATAATTTACAAT
TTTTTTAATAATGTGCAATTTAATATAGATAACCAAAATCTTTTTAATGAAAAGATCTTTACAATTGCTTGGAGGATAAGATTATTTTAC

>94291_94291_3_TRMT11-SLC16A10_TRMT11_chr6_126314968_ENST00000368332_SLC16A10_chr6_111527795_ENST00000368850_length(amino acids)=269AA_BP=68
MGFGREKEGPSAGRAGARWAAAMALSCTLNRYLLLMAQEHLEFRLPEIKSLLLLFGGQFASSQETYGKMKHVNERFQDEKNKEVVLMCIG
VTSGVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFELVGAQDVSQAIGFLLGF

--------------------------------------------------------------
>94291_94291_4_TRMT11-SLC16A10_TRMT11_chr6_126314968_ENST00000368332_SLC16A10_chr6_111527795_ENST00000368851_length(transcript)=1601nt_BP=210nt
TGGAGACTGGGCTTTGGGAGGGAGAAAGAGGGACCTAGCGCGGGCCGCGCAGGCGCACGGTGGGCAGCTGCAATGGCGCTGTCGTGTACC
CTTAACAGGTATCTGCTCCTCATGGCGCAGGAGCATCTGGAGTTCCGCCTGCCGGAAATAAAGTCTTTGCTTTTGCTTTTTGGAGGTCAG
TTTGCCAGCAGTCAAGAAACTTATGGAAAGATGAAACATGTAAATGAAAGATTTCAAGATGAAAAAAATAAAGAGGTTGTTCTCATGTGC
ATTGGCGTCACTTCAGGAGTTGGACGACTGCTCTTTGGCCGGATTGCAGATTATGTGCCTGGTGTGAAGAAGGTTTATCTACAGGTACTC
TCCTTTTTCTTCATTGGTCTGATGTCCATGATGATTCCTCTGTGTAGCATCTTTGGGGCCCTCATTGCTGTGTGCCTCATCATGGGTCTC
TTCGATGGATGCTTCATTTCCATTATGGCTCCCATAGCCTTTGAGTTAGTTGGTGCCCAGGATGTCTCCCAAGCAATTGGATTTCTGCTC
GGATTCATGTCTATACCCATGACTGTTGGCCCACCCATTGCAGGGTTACTTCGTGACAAACTGGGCTCCTATGATGTGGCATTCTACCTC
GCTGGAGTCCCTCCCCTTATTGGAGGTGCTGTGCTTTGTTTTATCCCGTGGATCCATAGTAAGAAGCAAAGAGAGATCAGTAAAACCACT
GGAAAAGAAAAGATGGAGAAAATGTTGGAAAACCAGAACTCTCTGCTGTCAAGTTCATCTGGAATGTTCAAGAAAGAATCTGACTCTATT
ATTTAATATCTTACATACCTCCACCAGACTGGACTTGCTTTTTGAATTTTAAGCAAGTTTCCTTTCCTTTTATACAAATTGCAAATTTCA
TATTTTTTTAATCACATCCTAGGAATAGCACAATAATTGGGAAATAGAACCCTTATCACTAGAAGAACCATTTTCTGCCACTAAATATCT
CTGATGTTTCCATGAGTCTGAGGGCAGAGACTCTGGTATATGAAAACGTCTGAAAGTCACATATTGTGAAAATTTGAAGCTATCTCAGTA
AAAAGCAGCTTTGGAAACTGTGAATGATCTTTAGCTTGTACAAATGTTTAAAAATACCTCAGGCTATACTGAAAGGGTTGCAGTTTGGTT
AGGAGTGGAAATATTTTGTTTGTTAATGATGTCTTCAGTTCTGGTACCTCTGTTTTACTTTCTTATGCTCTTTGGAAACTTTTTGCAAAA
TTTAAGCCTGGGTTCTAGATAATACCAGATCTACCTAAACCTCAAGTCTATGTTAAAGTTGCTTTCCTGCTGTTAAATAAGCTATGATAT
TAAGATATTCTGACTTGCTCCAGTGTCAAGGGACCTTCTGGGAGCAGGTGCTAACATAGTGTTCAGAATCAATATGTGAGATGAAAAGGA
TCCCCTCCAGGAGGATCCTGAGCTGTTCAGAAATCATTTAAGTTTACAGCGTTGTTCCCTTTGCGTTTGCAGTGCGTTTTACTCAAGTAG

>94291_94291_4_TRMT11-SLC16A10_TRMT11_chr6_126314968_ENST00000368332_SLC16A10_chr6_111527795_ENST00000368851_length(amino acids)=269AA_BP=68
MGFGREKEGPSAGRAGARWAAAMALSCTLNRYLLLMAQEHLEFRLPEIKSLLLLFGGQFASSQETYGKMKHVNERFQDEKNKEVVLMCIG
VTSGVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFELVGAQDVSQAIGFLLGF

--------------------------------------------------------------
>94291_94291_5_TRMT11-SLC16A10_TRMT11_chr6_126314968_ENST00000450358_SLC16A10_chr6_111527795_ENST00000368850_length(transcript)=9824nt_BP=259nt
CGCCTGCCTCGCAGAGCTTCCGCTTCCGGCCCTTCAGGCTCTGTCTCTGTGGAGACTGGGCTTTGGGAGGGAGAAAGAGGGACCTAGCGC
GGGCCGCGCAGGCGCACGGTGGGCAGCTGCAATGGCGCTGTCGTGTACCCTTAACAGGTATCTGCTCCTCATGGCGCAGGAGCATCTGGA
GTTCCGCCTGCCGGAAATAAAGTCTTTGCTTTTGCTTTTTGGAGGTCAGTTTGCCAGCAGTCAAGAAACTTATGGAAAGATGAAACATGT
AAATGAAAGATTTCAAGATGAAAAAAATAAAGAGGTTGTTCTCATGTGCATTGGCGTCACTTCAGGAGTTGGACGACTGCTCTTTGGCCG
GATTGCAGATTATGTGCCTGGTGTGAAGAAGGTTTATCTACAGGTACTCTCCTTTTTCTTCATTGGTCTGATGTCCATGATGATTCCTCT
GTGTAGCATCTTTGGGGCCCTCATTGCTGTGTGCCTCATCATGGGTCTCTTCGATGGATGCTTCATTTCCATTATGGCTCCCATAGCCTT
TGAGTTAGTTGGTGCCCAGGATGTCTCCCAAGCAATTGGATTTCTGCTCGGATTCATGTCTATACCCATGACTGTTGGCCCACCCATTGC
AGGGTTACTTCGTGACAAACTGGGCTCCTATGATGTGGCATTCTACCTCGCTGGAGTCCCTCCCCTTATTGGAGGTGCTGTGCTTTGTTT
TATCCCGTGGATCCATAGTAAGAAGCAAAGAGAGATCAGTAAAACCACTGGAAAAGAAAAGATGGAGAAAATGTTGGAAAACCAGAACTC
TCTGCTGTCAAGTTCATCTGGAATGTTCAAGAAAGAATCTGACTCTATTATTTAATATCTTACATACCTCCACCAGACTGGACTTGCTTT
TTGAATTTTAAGCAAGTTTCCTTTCCTTTTATACAAATTGCAAATTTCATATTTTTTTAATCACATCCTAGGAATAGCACAATAATTGGG
AAATAGAACCCTTATCACTAGAAGAACCATTTTCTGCCACTAAATATCTCTGATGTTTCCATGAGTCTGAGGGCAGAGACTCTGGTATAT
GAAAACGTCTGAAAGTCACATATTGTGAAAATTTGAAGCTATCTCAGTAAAAAGCAGCTTTGGAAACTGTGAATGATCTTTAGCTTGTAC
AAATGTTTAAAAATACCTCAGGCTATACTGAAAGGGTTGCAGTTTGGTTAGGAGTGGAAATATTTTGTTTGTTAATGATGTCTTCAGTTC
TGGTACCTCTGTTTTACTTTCTTATGCTCTTTGGAAACTTTTTGCAAAATTTAAGCCTGGGTTCTAGATAATACCAGATCTACCTAAACC
TCAAGTCTATGTTAAAGTTGCTTTCCTGCTGTTAAATAAGCTATGATATTAAGATATTCTGACTTGCTCCAGTGTCAAGGGACCTTCTGG
GAGCAGGTGCTAACATAGTGTTCAGAATCAATATGTGAGATGAAAAGGATCCCCTCCAGGAGGATCCTGAGCTGTTCAGAAATCATTTAA
GTTTACAGCGTTGTTCCCTTTGCGTTTGCAGTGCGTTTTACTCAAGTAGCCAGAAACACCCCACGTTTCTGAATTTGTTTAAACTGTAAC
AATAAAGTAAAATAGAATGCATGAAAGATATTCTGGCGATTGTAACTTAGAATTTTTCTGACTTCTGGATTTGTTGGCACTAGAACCTGA
TATTTAAAGTCTTACTGAGCAGCTATCAAGTGGCAGTTACAGGCACAAATTGGTGGAGGCTGGAGGATGGGGAGGGGAGCAAAACCCTTT
ATATTTGTGAAGAAAATATCTGTAGCTGATAGAAATAATTGCTTAAATTGGTTTATGAAATTAATGAGTCTGAAAAGGTTAAAAGCACTT
ATAAAAAGAACCAAGTCCTACATTTCCAGAACTTTCTGGCAAAAATTTGCACTCATATTATTTATCCTATGAACATTCCCATTGTTTTTT
TTTGCTATTTATATACAGATTATCATAAGAAAGCTCTCAGTTTGAGGACCCAAAATAAAACCAAAGTCATGCCATGACCCATACTCATTT
ACAAAAACAAGAACACTTTCCTCTATCCCTAAAATTATGCTTTAGTACTTGAGGCCTTTAAAAGTTAGTGCTTTTGATTGTGAAGACATT
CAGCAACTTACTTTGTCATACATGCAGTTGCACCTTACCACTTCTAATAGTGTCATATTTCATATTCAGGGGACTTAGATAATTTGCCTG
TGGATGGTTCTTTTGCAGGAAAAAAAATCTACATTTTGACCATACTACCCTTTCATGTCCTTATTATAAGCTTTTAGAAAATGATTTCAT
TCAGTCATGTCCAGTTATATAAAACGTTACTTTCTCATTTTTGAGAAGTTCAACAAAACATACTACTAAGACCAATCATCAAACCCACTA
TTATAAATGTTAATTTTGGCTGGGTAAGGTGGCTTGCGCCTATAATCCCAGCACTTTGGGAGGCTGAGGAGGGAAGATTGCTTGAGCCCA
GGAGTTTGAGACCAGCCTGGGCAACATAGCAAGATCCTGTCTCTACTAAAAATAAAAAAAAAAATTAGGCCAAGCATAGTGGCTCATGCC
TGTAATCCTAGCACTTTGGTAGTCCAAGGCAGGGGGATCACTTGAGCCCAGAAGTTCAAGACCAGCTTGGGTAACATAATGAGACCCTGT
GTCTACAAAAAATTTAAAAATTAGCCAGGCATGATGGTGCCCACCTGTAGCCCCAGCTACTCAGAGGCTGAGGTAGTGGAAGGATTGCTT
GAGCCTTGAGATGGAGGCTGCAGTGAGCTATGCCACTGTACTCTAGCCTGTTCAACTGAGCAGAACCCTGTCTGTAAAAGAAAATCAAAA
ACAAAAAATAAATGTTAAATTTTGTTTTAAGTTTTAGCACAGACTCCCCTCAAAACACCTTCTCCCCAATTTTACAGAAAGTAATTTAAA
AATGAAAACTTTACTCTGTAAAGACCTCTACAGTGTTTTTCTTTTCAAAATTTGGCTGATTTTAGGAAAAAAGTGATCATCTGAAACTAA
AAGAAATTGCTTGGTTAGTTTCCATATTAAAACAGCAGTGACAAGTATATATAACTTAGATCTCAGCATATGTGTTTGTATATTAAACTT
CACATATGTAGTTTTCAGTTTAATGGAATGAATCAAACTGGATCTATAACACTGAAAAAGTTCTATTGTAATAGACTCATACGGAGAATA
CTCTGCTATAATAATATAAAATTAAGAAGAAAAAGTATAAACGTAAGATGCTAAATTCCATAAATGCATATTTAGTACTATGTTTTTTGT
GGGAAAAGTTCTAAAAGTTTAAAATGCACAAAGAAAATGAAAAATACTAATATAAAAATTTGTGCTTTAATCTAGTCAAACTAAATCCTT
TCTAATTTCTGAATGAAGTGTTACTGCTGCAATAAAGTGACCTGATAAGCCTAAATTTTTTGTGTTCAATCCAGACACTTTTCTGAGAGT
CTGAAAAGAATACAGAGTCAGAACTCTGTTTTTATCTCCTCATCCTGTTTTTGATAAGACTCAGAAAATTCTCAAATTCGAAAGGTTCTG
GCATTTGAGGCCAAAAAAAGCATGAAAGGGAGTAACATTCCTTTTTATAGATACTCTAGATTGGATACTATTGTAACAGATGGCCAAGAA
ACTTCCAGAAACATTTTGGTTAAATTTTATTGCAATGGATATTGCTGGGATCCATCCATTTAAGCAGTAATATACCACCCAGATTATTGA
TACTTTATGCAAGATGTGTTCATCTCTTTGATCATATTTACAATGCTTACTCCATAGCCCTGCTACAAGACTTAAAATTTCCACTGAAAA
TTGCATAGTTCTTGTATTAAGATTCAAATTCTGGCTGGGCGCAGTGGCTCACGCTTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCG
GATTGCCTGAGCTCAGGAGTTCGCAACCAGCCTGGGAAACACGGTGAAGCTCCATCTCTACTAAAATACAAAAAAATTAGCCAGGCGTGT
CGGCATGCACCTGTAGTCCCAGCTACTCGGGAAGCTGAGGCAGGAGAAGAATCCAGGAGGCAGAGGTTGCAGTGAGGCGAGATTGCGCCA
CTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGTAAAAGTACACACAGTTTAAAAGTAAACATGTT
TACTTCGGATAATTCTAATCCTTTTAGCTGCATTTAAGAATATTTTAATTTATACGAATGTTACTTGAAATTGGCCTATGTCCAGATGAC
TTTTGATGTTAAATCAATGGAAAACTGAATAGAAAATATGACACGAGATCGGGGAGGGGGAAGGCAACCTATAGCATGGGTGGCTCTGAG
GAGTTCCTGCTGGTGCACTTTCATGCCCTTTCTTATGTACCTTTTGTCTTACTCTTCTTACATTATTCTTATCCTCATCATTTTTTCATT
TCCCTTTACTTCCTCCTATCCTTCAAAAACCTCCTGAAGAGTCCATTAACATCCATGCTTAGTTCCACTGGTTGCATGGCTGTATTTCCT
ACTGATCCCTGTAGTTTCACTGAATGGATCCCCACCCAATTTCGTGTATCCTGGTGAATGGCTTTCTCTCAGCCTTCGACTTAGTTCTAA
TGATCTACATTGAATTTAAATTACATGACTGAAATATTTAAGGGAAGAAATAAATTTCATACAAATTAGTATCTTTTATGCTAACATTTA
AAACTGTATTTAAATTTTTAAGGTAAATGCTTTGGGGAAAAAAAAAACCATTGCCAAGTCTTTAGCATATTTTCAGAGAGCGTAATTTTT
TACTTTGATTTCCAGTTTCACTAAGGTTTCATTAAATCTTAGTTCCGAGAGCCCAGCATGAAGGGTGACTGGGAATGTAGTGTGCCTCTC
TGATGCAGTTCCTAATGATTGTTCTTCAGGGACCTTCCTTAGGTTAGGTTACATTTTCTGGTGAATGGTGTTAGAGTAAATTCCCAGAGT
TTAGAGATACAAGTAGAAATGCATAAGCTAATTAGCTCCAATTTTATAATATGTAAACAATTTAAACAAGTATTTAAAACTTTTTAGGAA
GTCTCTAACACTGAAAAAAAGGTCATTGTTGCTGGTATAAACATTAAGGAGCAACTTTTACATTAGGTCAAAGATTGTTGCTTTTCCAGT
GTGTTGTCTTAAAAATAGAAGGAAATAAAACTATTACCTTCTTTTTACATCTATATGTTTTTATAATTTGAAAGGCAAGTAGTATCTTGG
TGAATAAGAAATGCATCATCCATAACAATTTAATTAACTCTTAAAAAGACCAGCTTTTTGTCTTGTTATGAAAACAAAACGCAATTTGTC
ATTCATAATGGTAATGTGGAATAAGAATACATCGTAGAAGGAAGACTTGCTACTTTACTGACTTAATCATTAGTTCTAAGGCCATGTGTG
GCGGCTCACGCCTGTAATCCCAGCACTTTGGGAGTCCAAGGCGGTAGGATCACCAGAGCCCAGGGTTCAAGACTCAGCCTGGGCAACATA
GTGAGATTTCGTCTCTACAAAAAAAATTTAGCCAGCTTGGTGGCACATGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAAGAGGATT
GCTTGAGCATAGCAGGTCAAGTCTGCAGTGAGCTGTGGTTGCACCACTGCACTCCAGCCTGGGTGACAAAATGAGACCTTGTCTACAAAA
AGGAAAAAAAAATTTGTTCTGCTCTACTATACATGCTGACTTTTGTTGATAGCTTGGTCTAAAAAGACTGTCTAGAGCTGAATTTAAGAA
TGGTTCTGGAGCAAATAATAACAAGGTAGACAAGCAGGCCCTGGGCTCACTATAATTTCATAGCCACGACCTGTTTATTATTAGTTGGCA
GAGATTAATGCTTTGTGTTATAAATATACTATAGAACAATAGGTCACGATTCTCAAGAACAAAGCCGAATGCTCGCAGTTAAGTGTGAAG
CTTGCATAAGTGTCGGAACCACAATTATGGACCCACCATCAATGTGCATTTTATCAGATGACTCCTCCTGAGACAGTAAAGACTCCTGGA
AAATTCATGACATCTTTGAATCACTCAGAAAAATCTTGAAACTCAGGACGTAGTTTACTTAGCTTGCCTTTTTTAAAATTATCAAATTTT
AAATCGTAAACTTTGTCTTCACTTCCACACGTTCAAGGACACCTCTTTTAAAGTTCAGTGTTCCATACTAAAGGGGTGTAATCTTGCTTT
CTGGGGAAATAAAATTCCCCATGGTACTATATTCCTGACAGATATAAAATAACATGAGGCTACCTCATTTTTGAAATAGATTTCAATATT
TTTATTAGTAAGTTGGAAAGACAGTAGGAACAAAATGAAACCTTTCTAAGTACTTGATGACACCCACTTGATCATGACAATTCATCTACC
TCCGCTTTCCGTGTCCAGCTGAAAGCCCAGCTGAGTCAACTCCTGCTTCATCAGAAGGGAGCTAATGGTGATTCTGGGATTAAAAAGCAA
GGGGGGTGCAAATTGTTAGTGGGGTCAAAATATCAGTAAAATTTCTTAAGTGCTTTGTTCTGATAAACGGATGTAAAAGTAACAAAAAAG
GAATAACAACTAATATGGCCTGTGGATCTGACAAAGAAAAACCTGAAGAAATTCAGAATCTAGATACACTTAGATTCTAAATTAGACACA
CTCAGATTCTAATGAACACTTAGAATGCTTCGCCAGTGGCTTTTCAAGTTACACTGGAAGCTTGATTATGAAAAAGTTTTGTTTTCATTG
GCAAGAGGGTAGATGATCAGTGATGACAGATTGTACAGCTGTGCCCAAACCTGACAACTTACACATTAAACTCCTGTAAGAGACACTCCT
TCCTAGTAGAACAAGGACTGGGACAATGAATTTTTGACTCACTGGAGTTTTTTAAAATGCTGTTCTTGAGTGTGGCAATAGTGTAGGAGT
TAACCCAGTCTACCCAAAGAAGTTGCTTTGCCTTTCAATATGAGTGCTATAAAAAGAGTATTTTGGAGTTCAATGTCCCTAAACATGTAT
GCGATAGGAACTACCAATATAAAATAACACTTAGAACTCAAATTAGATTGGTAATACTATTTTGGAGCCTGTGATGTATGACTTTTATTC
TTTACTAGATATTTTTCAGTATCCGTCATTAGAAGAGTCAGTTTGTTAAATATTTTAAATGTGTAAACACAAAACCTTTCTACTGTGATC
TTCCCTAATGAGTCAAAGTATCTTTCATAATTCAGTCTATATTGAAATGTTATTTCAGGAATGGAGGGTTTGTTATTAATAGTGCTGGGC
CGGGCACGGTGACTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGACAGGCGAATCACCTGAGGTCAGATGTTGGAGACCAGCCTGA
CCAACATGGAGAAACCCCATCTCTACCAAAAATACAAAATTAGCCGGGCGTGGTGGCTCCATGCTGTAATCCCAGCTACTCGGGAGGCTG
AGGCAGGAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATTGCACCATAGCACTCCAGCCTGGGCAACAAGAGCAAAA
CTCTGTCTCAAAAAAAAAAAAAAAAAAAATAGTGCTGCATTTTGACCCTGGACTATGAACAGACTGTATAGTTGGTGCCTCTTTTTTTTC
TACCAAAGATTATTAGATCAAGATTGGTGCTATACTTCATGTTCCTTTCAAAATTATTTTTCTTTTAAAAATATTAATATACAACACAAT
AGAAAATGTATACAGCCAGCAACGTTATGCATGTTGCATGTTATATACATGACTGAGGAAAAAAGCTCACCTATACAGTGATTATTGAGT
TCCAGTATCTAGTTAGAGGTATGCAATTTTTGTTAACATATAAGACTTTAAATTACGAAACTCACAAGAAAATGATCACCAAATGAGAAT
GTTCTAATGAACACAACCTCCCAAGGTAATAATTTTAAAGAAAAAGTCCCTTGTCAATGTTTCTAGCACAAAGTGAGGGATTTAAATATA
TTCTGTAACTTTGAGGCAATGTGAAAAAGTTATATATAATAGCTTCCTATTGAGCTGGCTTATGTAGACATTTGGACATTTGAAACTATT
TCGCAACTTTCAGGCTAAAATCAGAGTTTTGAGAGTCATCAATCTTAAAACATGGATAATGAGTTATTTGCACAGTTATATTTTTATAAT
TATTTGAAATTTATCACTGAAAGTATCATTGTTTGTCTTTCAGATTTAACATAAACAATAAGTACTGCGGCTGGGTCACTGTCAGCAAAT
CTCAGGTCTATGATTTATCAAGGGCTCTCAGCACCATCGTTGGTCTGATTGTGTAACACCTAAGTAAAATAACATATGGGTCTCCTTGGC
CAGGCGCCGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCGGATTGCTTGAGGCCAGGAGTTCGAGACATACGGGT
CTCTTTAATGTTCTGTAGGTAGGATTCAGATGAATTGAGAATGACAGGTTTCTTTTTCTTTCTTTGTTTCTTTTTTTTTTTTTTTTTTGA
GATGGAGTCTTGCTCTATTGCCAGGCTCCATATAGTGGCGCGATCTCAGCTCACTGCAACCTCCGCCTCCCGGGCTCAAGTGATTCTCGT
GCCTCAGTCTTCTGAGTAGCTGGGACTACAGGTGCCCACTACCACACCGGCTAATTTTTGTATTTTTGGTAGAGATGGAGTTTCACCATG
TTGGCCAGACTGGCCTTAAGTGATCCACCTGCCTCAGCCTCCCCAAGTGCTGGAATTACAGGCATGAGCCACCATGCCCGGCTAGAGAAT
GACAGGTTTCAGTTGAATTCTTCTCTTTTAAAAGACCCTGACTTAACTGTATTTTATGAGGATTTTATAAATGTAAATTAAGAAGACAAT
ACACACTCTCATTTTCCTAATTAGAAAGACTATGCATTCACAATCCAGTACACTGGATTTGCTCTGGTAACTAATGATAACACTTTTCTA
CGTTAACATGAGTTATATTTGGCAGAGAGAATGGAAGCTTGCTAATCAGAAGTTACATTAGGGTGAGATTAAACATCACTCTAATAATAA
CTTCTGATGTAACTTAATGTGGTTTGAGATGTGTAAGATTGTAGAGGCATTGCACAATGCTTGATAAAAGTTGCATTTTGCTTTTGTTCT
TCCACCAGTTTATTTTAGCCTTAAAGTTATAGCTACAACAAATTGAACCCTGTAGTTATTACTGAAAGAGAGTGTGGATATTTTAAGTAT
CTCCTAGTATAATATGACATTGTTCATGTGGACTTATTTTAATGTTTATTTGAAAATTAATTTTTTAATTATTTTGTATATTTTGAGTTA
GAAAAACACACTTTATCTTAGACACCAAAGCCAAATTATTCCAAGTGTATGCTATACACCGCAGTGCAGCTCTGCTTCTCTCCCAACCTA
CCCTGGGGCCATTTTTGGCACAATAGTTGTTCAAATGTAGATCACTATGCTGAATGCTCATGCTGGATTTGACCAGTATGCAGTATTTTA
GTACTTTTTAAAAAATGTATGCTTCTTTTTGAAGACTATAATTTACAATTTTTTTAATAATGTGCAATTTAATATAGATAACCAAAATCT
TTTTAATGAAAAGATCTTTACAATTGCTTGGAGGATAAGATTATTTTACTGTGGAAAAATGTGATACTCTTAGTAAATGCAATAAAAACT

>94291_94291_5_TRMT11-SLC16A10_TRMT11_chr6_126314968_ENST00000450358_SLC16A10_chr6_111527795_ENST00000368850_length(amino acids)=274AA_BP=73
MSLWRLGFGREKEGPSAGRAGARWAAAMALSCTLNRYLLLMAQEHLEFRLPEIKSLLLLFGGQFASSQETYGKMKHVNERFQDEKNKEVV
LMCIGVTSGVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFELVGAQDVSQAIG
FLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIPWIHSKKQREISKTTGKEKMEKMLENQNSLLSSSSGMFKKES

--------------------------------------------------------------
>94291_94291_6_TRMT11-SLC16A10_TRMT11_chr6_126314968_ENST00000450358_SLC16A10_chr6_111527795_ENST00000368851_length(transcript)=1650nt_BP=259nt
CGCCTGCCTCGCAGAGCTTCCGCTTCCGGCCCTTCAGGCTCTGTCTCTGTGGAGACTGGGCTTTGGGAGGGAGAAAGAGGGACCTAGCGC
GGGCCGCGCAGGCGCACGGTGGGCAGCTGCAATGGCGCTGTCGTGTACCCTTAACAGGTATCTGCTCCTCATGGCGCAGGAGCATCTGGA
GTTCCGCCTGCCGGAAATAAAGTCTTTGCTTTTGCTTTTTGGAGGTCAGTTTGCCAGCAGTCAAGAAACTTATGGAAAGATGAAACATGT
AAATGAAAGATTTCAAGATGAAAAAAATAAAGAGGTTGTTCTCATGTGCATTGGCGTCACTTCAGGAGTTGGACGACTGCTCTTTGGCCG
GATTGCAGATTATGTGCCTGGTGTGAAGAAGGTTTATCTACAGGTACTCTCCTTTTTCTTCATTGGTCTGATGTCCATGATGATTCCTCT
GTGTAGCATCTTTGGGGCCCTCATTGCTGTGTGCCTCATCATGGGTCTCTTCGATGGATGCTTCATTTCCATTATGGCTCCCATAGCCTT
TGAGTTAGTTGGTGCCCAGGATGTCTCCCAAGCAATTGGATTTCTGCTCGGATTCATGTCTATACCCATGACTGTTGGCCCACCCATTGC
AGGGTTACTTCGTGACAAACTGGGCTCCTATGATGTGGCATTCTACCTCGCTGGAGTCCCTCCCCTTATTGGAGGTGCTGTGCTTTGTTT
TATCCCGTGGATCCATAGTAAGAAGCAAAGAGAGATCAGTAAAACCACTGGAAAAGAAAAGATGGAGAAAATGTTGGAAAACCAGAACTC
TCTGCTGTCAAGTTCATCTGGAATGTTCAAGAAAGAATCTGACTCTATTATTTAATATCTTACATACCTCCACCAGACTGGACTTGCTTT
TTGAATTTTAAGCAAGTTTCCTTTCCTTTTATACAAATTGCAAATTTCATATTTTTTTAATCACATCCTAGGAATAGCACAATAATTGGG
AAATAGAACCCTTATCACTAGAAGAACCATTTTCTGCCACTAAATATCTCTGATGTTTCCATGAGTCTGAGGGCAGAGACTCTGGTATAT
GAAAACGTCTGAAAGTCACATATTGTGAAAATTTGAAGCTATCTCAGTAAAAAGCAGCTTTGGAAACTGTGAATGATCTTTAGCTTGTAC
AAATGTTTAAAAATACCTCAGGCTATACTGAAAGGGTTGCAGTTTGGTTAGGAGTGGAAATATTTTGTTTGTTAATGATGTCTTCAGTTC
TGGTACCTCTGTTTTACTTTCTTATGCTCTTTGGAAACTTTTTGCAAAATTTAAGCCTGGGTTCTAGATAATACCAGATCTACCTAAACC
TCAAGTCTATGTTAAAGTTGCTTTCCTGCTGTTAAATAAGCTATGATATTAAGATATTCTGACTTGCTCCAGTGTCAAGGGACCTTCTGG
GAGCAGGTGCTAACATAGTGTTCAGAATCAATATGTGAGATGAAAAGGATCCCCTCCAGGAGGATCCTGAGCTGTTCAGAAATCATTTAA
GTTTACAGCGTTGTTCCCTTTGCGTTTGCAGTGCGTTTTACTCAAGTAGCCAGAAACACCCCACGTTTCTGAATTTGTTTAAACTGTAAC

>94291_94291_6_TRMT11-SLC16A10_TRMT11_chr6_126314968_ENST00000450358_SLC16A10_chr6_111527795_ENST00000368851_length(amino acids)=274AA_BP=73
MSLWRLGFGREKEGPSAGRAGARWAAAMALSCTLNRYLLLMAQEHLEFRLPEIKSLLLLFGGQFASSQETYGKMKHVNERFQDEKNKEVV
LMCIGVTSGVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFELVGAQDVSQAIG
FLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIPWIHSKKQREISKTTGKEKMEKMLENQNSLLSSSSGMFKKES

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for TRMT11-SLC16A10


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for TRMT11-SLC16A10


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for TRMT11-SLC16A10


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource