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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TSFM-CNOT2 (FusionGDB2 ID:94546)

Fusion Gene Summary for TSFM-CNOT2

check button Fusion gene summary
Fusion gene informationFusion gene name: TSFM-CNOT2
Fusion gene ID: 94546
HgeneTgene
Gene symbol

TSFM

CNOT2

Gene ID

10102

4848

Gene nameTs translation elongation factor, mitochondrialCCR4-NOT transcription complex subunit 2
SynonymsEFTS|EFTSMTCDC36|HSPC131|IDNADFS|NOT2|NOT2H
Cytomap

12q14.1

12q15

Type of geneprotein-codingprotein-coding
Descriptionelongation factor Ts, mitochondrialEF-TsEF-TsMtmitochondrial elongation factor TsCCR4-NOT transcription complex subunit 2CCR4-associated factor 2negative regulator of transcription 2
Modification date2020031320200313
UniProtAcc.

Q9NZN8

Ensembl transtripts involved in fusion geneENST00000497617, ENST00000323833, 
ENST00000454289, ENST00000540550, 
ENST00000543727, ENST00000548851, 
ENST00000550559, ENST00000350762, 
ENST00000229195, ENST00000418359, 
ENST00000551483, ENST00000548230, 
Fusion gene scores* DoF score26 X 8 X 7=145627 X 20 X 10=5400
# samples 3029
** MAII scorelog2(30/1456*10)=-2.27897594970282
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(29/5400*10)=-4.21883460192326
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TSFM [Title/Abstract] AND CNOT2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTSFM(58177066)-CNOT2(70732223), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTSFM

GO:0070129

regulation of mitochondrial translation

27677415

TgeneCNOT2

GO:0000122

negative regulation of transcription by RNA polymerase II

14707134|16712523


check buttonFusion gene breakpoints across TSFM (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CNOT2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-A7TK-01ATSFMchr12

58177066

+CNOT2chr12

70732223

+


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Fusion Gene ORF analysis for TSFM-CNOT2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000497617ENST00000229195TSFMchr12

58177066

+CNOT2chr12

70732223

+
3UTR-3CDSENST00000497617ENST00000418359TSFMchr12

58177066

+CNOT2chr12

70732223

+
3UTR-5UTRENST00000497617ENST00000551483TSFMchr12

58177066

+CNOT2chr12

70732223

+
3UTR-intronENST00000497617ENST00000548230TSFMchr12

58177066

+CNOT2chr12

70732223

+
5CDS-5UTRENST00000323833ENST00000551483TSFMchr12

58177066

+CNOT2chr12

70732223

+
5CDS-5UTRENST00000454289ENST00000551483TSFMchr12

58177066

+CNOT2chr12

70732223

+
5CDS-5UTRENST00000540550ENST00000551483TSFMchr12

58177066

+CNOT2chr12

70732223

+
5CDS-5UTRENST00000543727ENST00000551483TSFMchr12

58177066

+CNOT2chr12

70732223

+
5CDS-5UTRENST00000548851ENST00000551483TSFMchr12

58177066

+CNOT2chr12

70732223

+
5CDS-5UTRENST00000550559ENST00000551483TSFMchr12

58177066

+CNOT2chr12

70732223

+
5CDS-intronENST00000323833ENST00000548230TSFMchr12

58177066

+CNOT2chr12

70732223

+
5CDS-intronENST00000454289ENST00000548230TSFMchr12

58177066

+CNOT2chr12

70732223

+
5CDS-intronENST00000540550ENST00000548230TSFMchr12

58177066

+CNOT2chr12

70732223

+
5CDS-intronENST00000543727ENST00000548230TSFMchr12

58177066

+CNOT2chr12

70732223

+
5CDS-intronENST00000548851ENST00000548230TSFMchr12

58177066

+CNOT2chr12

70732223

+
5CDS-intronENST00000550559ENST00000548230TSFMchr12

58177066

+CNOT2chr12

70732223

+
5UTR-3CDSENST00000350762ENST00000229195TSFMchr12

58177066

+CNOT2chr12

70732223

+
5UTR-3CDSENST00000350762ENST00000418359TSFMchr12

58177066

+CNOT2chr12

70732223

+
5UTR-5UTRENST00000350762ENST00000551483TSFMchr12

58177066

+CNOT2chr12

70732223

+
5UTR-intronENST00000350762ENST00000548230TSFMchr12

58177066

+CNOT2chr12

70732223

+
In-frameENST00000323833ENST00000229195TSFMchr12

58177066

+CNOT2chr12

70732223

+
In-frameENST00000323833ENST00000418359TSFMchr12

58177066

+CNOT2chr12

70732223

+
In-frameENST00000454289ENST00000229195TSFMchr12

58177066

+CNOT2chr12

70732223

+
In-frameENST00000454289ENST00000418359TSFMchr12

58177066

+CNOT2chr12

70732223

+
In-frameENST00000540550ENST00000229195TSFMchr12

58177066

+CNOT2chr12

70732223

+
In-frameENST00000540550ENST00000418359TSFMchr12

58177066

+CNOT2chr12

70732223

+
In-frameENST00000543727ENST00000229195TSFMchr12

58177066

+CNOT2chr12

70732223

+
In-frameENST00000543727ENST00000418359TSFMchr12

58177066

+CNOT2chr12

70732223

+
In-frameENST00000548851ENST00000229195TSFMchr12

58177066

+CNOT2chr12

70732223

+
In-frameENST00000548851ENST00000418359TSFMchr12

58177066

+CNOT2chr12

70732223

+
In-frameENST00000550559ENST00000229195TSFMchr12

58177066

+CNOT2chr12

70732223

+
In-frameENST00000550559ENST00000418359TSFMchr12

58177066

+CNOT2chr12

70732223

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000543727TSFMchr1258177066+ENST00000229195CNOT2chr1270732223+208928861010334
ENST00000543727TSFMchr1258177066+ENST00000418359CNOT2chr1270732223+208928861010334
ENST00000550559TSFMchr1258177066+ENST00000229195CNOT2chr1270732223+204724615968317
ENST00000550559TSFMchr1258177066+ENST00000418359CNOT2chr1270732223+204724615968317
ENST00000548851TSFMchr1258177066+ENST00000229195CNOT2chr1270732223+204724615968317
ENST00000548851TSFMchr1258177066+ENST00000418359CNOT2chr1270732223+204724615968317
ENST00000454289TSFMchr1258177066+ENST00000229195CNOT2chr1270732223+2245444421166374
ENST00000454289TSFMchr1258177066+ENST00000418359CNOT2chr1270732223+2245444421166374
ENST00000540550TSFMchr1258177066+ENST00000229195CNOT2chr1270732223+208928861010334
ENST00000540550TSFMchr1258177066+ENST00000418359CNOT2chr1270732223+208928861010334
ENST00000323833TSFMchr1258177066+ENST00000229195CNOT2chr1270732223+205825726979317
ENST00000323833TSFMchr1258177066+ENST00000418359CNOT2chr1270732223+205825726979317

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000543727ENST00000229195TSFMchr1258177066+CNOT2chr1270732223+0.0006897690.99931026
ENST00000543727ENST00000418359TSFMchr1258177066+CNOT2chr1270732223+0.0006897690.99931026
ENST00000550559ENST00000229195TSFMchr1258177066+CNOT2chr1270732223+0.0007107430.9992893
ENST00000550559ENST00000418359TSFMchr1258177066+CNOT2chr1270732223+0.0007107430.9992893
ENST00000548851ENST00000229195TSFMchr1258177066+CNOT2chr1270732223+0.0007107430.9992893
ENST00000548851ENST00000418359TSFMchr1258177066+CNOT2chr1270732223+0.0007107430.9992893
ENST00000454289ENST00000229195TSFMchr1258177066+CNOT2chr1270732223+0.0068120150.993188
ENST00000454289ENST00000418359TSFMchr1258177066+CNOT2chr1270732223+0.0068120150.993188
ENST00000540550ENST00000229195TSFMchr1258177066+CNOT2chr1270732223+0.0006897690.99931026
ENST00000540550ENST00000418359TSFMchr1258177066+CNOT2chr1270732223+0.0006897690.99931026
ENST00000323833ENST00000229195TSFMchr1258177066+CNOT2chr1270732223+0.0007065820.99929345
ENST00000323833ENST00000418359TSFMchr1258177066+CNOT2chr1270732223+0.0007065820.99929345

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Fusion Genomic Features for TSFM-CNOT2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TSFMchr1258177066+CNOT2chr1270732222+0.0050915990.9949084
TSFMchr1258177066+CNOT2chr1270732222+0.0050915990.9949084

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for TSFM-CNOT2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:58177066/chr12:70732223)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CNOT2

Q9NZN8

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specifically involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of embryonic stem (ES) cell identity. {ECO:0000269|PubMed:14707134, ECO:0000269|PubMed:16712523, ECO:0000269|PubMed:21299754, ECO:0000269|PubMed:22367759}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCNOT2chr12:58177066chr12:70732223ENST00000229195816437_540300541.0RegionNote=Repressor domain
TgeneCNOT2chr12:58177066chr12:70732223ENST00000418359917437_540300541.0RegionNote=Repressor domain
TgeneCNOT2chr12:58177066chr12:70732223ENST0000055148307437_5400192.0RegionNote=Repressor domain

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for TSFM-CNOT2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>94546_94546_1_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000323833_CNOT2_chr12_70732223_ENST00000229195_length(transcript)=2058nt_BP=257nt
GGAGGGTGTTTATCGCGGCTAGAGAGATGTCGCTGCTGCGGTCGCTGCGCGTGTTTCTGGTCGCGCGGACCGGGAGCTACCCGGCTGGGT
CTCTTCTGCGTCAGTCGCCCCAGCCAAGGCACACATTTTATGCTGGGCCCCGTCTGTCTGCCTCGGCCTCCAGCAAGGAGCTCCTCATGA
AGCTGCGGCGGAAAACAGGCTACTCCTTTGTAAATTGCAAGAAAGCTCTGGAGACTTGTGGCGGGGACCTCAAACAGAATTTGAATACAT
CTGGCAAGACAACTTCAAGTACAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACAACACAAAATAATAACCAGCAGAAAAAAGGGA
TCCAGGTGTTACCTGATGGTCGGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAATTTGGAATGATTGGCCTGTTAACATTTATCA
GGGCAGCAGAGACAGACCCAGGAATGGTACATCTTGCATTAGGAAGTGACTTAACAACATTAGGCCTCAATCTGAACTCTCCTGAAAATC
TCTACCCCAAATTTGCGTCACCCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGACTTCCATGTTCCATCTGAGTACTTAACGAACA
TTCACATTAGGGATAAGCTGGCTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTCTTCTATCTCTATTACATGAATGGAGGAGACG
TATTACAACTTTTAGCTGCAGTGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAAGAACGAGTATGGATTACCAGGGCACCAGGCA
TGGAGCCAACAATGAAAACCAATACCTATGAGAGGGGAACATATTACTTCTTTGACTGTCTTAACTGGAGGAAAGTAGCTAAGGAGTTCC
ATCTGGAATATGACAAATTAGAAGAACGGCCTCACCTGCCATCCACCTTCAACTACAACCCTGCTCAGCAAGCCTTCTAAAAAAAAAAAA
AAAAAAAAAAAAAGACTTCCCTTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAACATAACTGCAGAACTGATGTGGCTCAGGCACC
CTGGTTTTAATTCCTTGAGGATCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGGTCCTGCCTTACTAATTATGTGCTGCCCAACA
ACTAAATTTGTAATTTGTTTTTCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATTTCCTTTTTTGCCAGCAGACAGACTTGAGTCT
GTAAAGACAAGCAAATACACTGACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGAAAACCCCCAAAAGACTCAAGAAAATTAGACC
ACAAATTTTGCATTGTTCATTGTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCATTTTTATGTGAAGATCCTTCTCGTATTTCAT
TTGGAAAGATGAGCAAGAGGTCTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAAGGCAGTTTCGCCAAGCTTAATGCAAGAATAT
CTGACTGTTTAGAAGAAAGATATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTTATTACTGAGCTTCATCTTTCCAGAATGAGCA
AAACACTGTCCAGTCTTTGTTACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTTTTGGACATCACATGAATAAAGGTATGTATGT
ACGAATGTGTATATATTATATATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTACCTCATTTTTAGGAGGTGTGCATGGATGCAA
TATATGAAAATGGGACATTCTGGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACTAAAAGGGCCAGATTTTCAGCAGCCAAGGACA
TCCATACCCAAGTGAATGTGATGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTGGCTGTTTGAACAGCAGCGTTTCATAGGAAGA

>94546_94546_1_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000323833_CNOT2_chr12_70732223_ENST00000229195_length(amino acids)=317AA_BP=77
MSLLRSLRVFLVARTGSYPAGSLLRQSPQPRHTFYAGPRLSASASSKELLMKLRRKTGYSFVNCKKALETCGGDLKQNLNTSGKTTSSTD
GPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPW
ASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNT

--------------------------------------------------------------
>94546_94546_2_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000323833_CNOT2_chr12_70732223_ENST00000418359_length(transcript)=2058nt_BP=257nt
GGAGGGTGTTTATCGCGGCTAGAGAGATGTCGCTGCTGCGGTCGCTGCGCGTGTTTCTGGTCGCGCGGACCGGGAGCTACCCGGCTGGGT
CTCTTCTGCGTCAGTCGCCCCAGCCAAGGCACACATTTTATGCTGGGCCCCGTCTGTCTGCCTCGGCCTCCAGCAAGGAGCTCCTCATGA
AGCTGCGGCGGAAAACAGGCTACTCCTTTGTAAATTGCAAGAAAGCTCTGGAGACTTGTGGCGGGGACCTCAAACAGAATTTGAATACAT
CTGGCAAGACAACTTCAAGTACAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACAACACAAAATAATAACCAGCAGAAAAAAGGGA
TCCAGGTGTTACCTGATGGTCGGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAATTTGGAATGATTGGCCTGTTAACATTTATCA
GGGCAGCAGAGACAGACCCAGGAATGGTACATCTTGCATTAGGAAGTGACTTAACAACATTAGGCCTCAATCTGAACTCTCCTGAAAATC
TCTACCCCAAATTTGCGTCACCCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGACTTCCATGTTCCATCTGAGTACTTAACGAACA
TTCACATTAGGGATAAGCTGGCTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTCTTCTATCTCTATTACATGAATGGAGGAGACG
TATTACAACTTTTAGCTGCAGTGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAAGAACGAGTATGGATTACCAGGGCACCAGGCA
TGGAGCCAACAATGAAAACCAATACCTATGAGAGGGGAACATATTACTTCTTTGACTGTCTTAACTGGAGGAAAGTAGCTAAGGAGTTCC
ATCTGGAATATGACAAATTAGAAGAACGGCCTCACCTGCCATCCACCTTCAACTACAACCCTGCTCAGCAAGCCTTCTAAAAAAAAAAAA
AAAAAAAAAAAAAGACTTCCCTTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAACATAACTGCAGAACTGATGTGGCTCAGGCACC
CTGGTTTTAATTCCTTGAGGATCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGGTCCTGCCTTACTAATTATGTGCTGCCCAACA
ACTAAATTTGTAATTTGTTTTTCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATTTCCTTTTTTGCCAGCAGACAGACTTGAGTCT
GTAAAGACAAGCAAATACACTGACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGAAAACCCCCAAAAGACTCAAGAAAATTAGACC
ACAAATTTTGCATTGTTCATTGTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCATTTTTATGTGAAGATCCTTCTCGTATTTCAT
TTGGAAAGATGAGCAAGAGGTCTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAAGGCAGTTTCGCCAAGCTTAATGCAAGAATAT
CTGACTGTTTAGAAGAAAGATATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTTATTACTGAGCTTCATCTTTCCAGAATGAGCA
AAACACTGTCCAGTCTTTGTTACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTTTTGGACATCACATGAATAAAGGTATGTATGT
ACGAATGTGTATATATTATATATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTACCTCATTTTTAGGAGGTGTGCATGGATGCAA
TATATGAAAATGGGACATTCTGGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACTAAAAGGGCCAGATTTTCAGCAGCCAAGGACA
TCCATACCCAAGTGAATGTGATGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTGGCTGTTTGAACAGCAGCGTTTCATAGGAAGA

>94546_94546_2_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000323833_CNOT2_chr12_70732223_ENST00000418359_length(amino acids)=317AA_BP=77
MSLLRSLRVFLVARTGSYPAGSLLRQSPQPRHTFYAGPRLSASASSKELLMKLRRKTGYSFVNCKKALETCGGDLKQNLNTSGKTTSSTD
GPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPW
ASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNT

--------------------------------------------------------------
>94546_94546_3_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000454289_CNOT2_chr12_70732223_ENST00000229195_length(transcript)=2245nt_BP=444nt
ATTTTACCTGGGGTGGGAGGTGGGGGGTAATTCCCGTATGAAATGTGTCGTCTCAAGAAATCAAGTAGAGGCGAGGACTGTGTTCCTCCG
GCCAGCAGGTGGCACCATACTCGTTTGGTGCGTTCCGCTGGAGAATTCTGGCCCTTCCGCCGCGCCGTAGGTTTGTTGCCTCACCAGTGC
GCCCGCCGGAGGGTGTTTATCGCGGCTAGAGAGATGTCGCTGCTGCGGTCGCTGCGCGTGTTTCTGGTCGCGCGGACCGGGAGCTACCCG
GCTGGGTCTCTTCTGCGTCAGTCGCCCCAGCCAAGGCACACATTTTATGCTGGGCCCCGTCTGTCTGCCTCGGCCTCCAGCAAGGAGCTC
CTCATGAAGCTGCGGCGGAAAACAGGCTACTCCTTTGTAAATTGCAAGAAAGCTCTGGAGACTTGTGGCGGGGACCTCAAACAGAATTTG
AATACATCTGGCAAGACAACTTCAAGTACAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACAACACAAAATAATAACCAGCAGAAA
AAAGGGATCCAGGTGTTACCTGATGGTCGGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAATTTGGAATGATTGGCCTGTTAACA
TTTATCAGGGCAGCAGAGACAGACCCAGGAATGGTACATCTTGCATTAGGAAGTGACTTAACAACATTAGGCCTCAATCTGAACTCTCCT
GAAAATCTCTACCCCAAATTTGCGTCACCCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGACTTCCATGTTCCATCTGAGTACTTA
ACGAACATTCACATTAGGGATAAGCTGGCTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTCTTCTATCTCTATTACATGAATGGA
GGAGACGTATTACAACTTTTAGCTGCAGTGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAAGAACGAGTATGGATTACCAGGGCA
CCAGGCATGGAGCCAACAATGAAAACCAATACCTATGAGAGGGGAACATATTACTTCTTTGACTGTCTTAACTGGAGGAAAGTAGCTAAG
GAGTTCCATCTGGAATATGACAAATTAGAAGAACGGCCTCACCTGCCATCCACCTTCAACTACAACCCTGCTCAGCAAGCCTTCTAAAAA
AAAAAAAAAAAAAAAAAAAAGACTTCCCTTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAACATAACTGCAGAACTGATGTGGCTC
AGGCACCCTGGTTTTAATTCCTTGAGGATCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGGTCCTGCCTTACTAATTATGTGCTG
CCCAACAACTAAATTTGTAATTTGTTTTTCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATTTCCTTTTTTGCCAGCAGACAGACT
TGAGTCTGTAAAGACAAGCAAATACACTGACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGAAAACCCCCAAAAGACTCAAGAAAA
TTAGACCACAAATTTTGCATTGTTCATTGTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCATTTTTATGTGAAGATCCTTCTCGT
ATTTCATTTGGAAAGATGAGCAAGAGGTCTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAAGGCAGTTTCGCCAAGCTTAATGCA
AGAATATCTGACTGTTTAGAAGAAAGATATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTTATTACTGAGCTTCATCTTTCCAGA
ATGAGCAAAACACTGTCCAGTCTTTGTTACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTTTTGGACATCACATGAATAAAGGTA
TGTATGTACGAATGTGTATATATTATATATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTACCTCATTTTTAGGAGGTGTGCATG
GATGCAATATATGAAAATGGGACATTCTGGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACTAAAAGGGCCAGATTTTCAGCAGCC
AAGGACATCCATACCCAAGTGAATGTGATGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTGGCTGTTTGAACAGCAGCGTTTCAT

>94546_94546_3_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000454289_CNOT2_chr12_70732223_ENST00000229195_length(amino acids)=374AA_BP=134
MCRLKKSSRGEDCVPPASRWHHTRLVRSAGEFWPFRRAVGLLPHQCARRRVFIAAREMSLLRSLRVFLVARTGSYPAGSLLRQSPQPRHT
FYAGPRLSASASSKELLMKLRRKTGYSFVNCKKALETCGGDLKQNLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNI
PQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKL
GRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPH

--------------------------------------------------------------
>94546_94546_4_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000454289_CNOT2_chr12_70732223_ENST00000418359_length(transcript)=2245nt_BP=444nt
ATTTTACCTGGGGTGGGAGGTGGGGGGTAATTCCCGTATGAAATGTGTCGTCTCAAGAAATCAAGTAGAGGCGAGGACTGTGTTCCTCCG
GCCAGCAGGTGGCACCATACTCGTTTGGTGCGTTCCGCTGGAGAATTCTGGCCCTTCCGCCGCGCCGTAGGTTTGTTGCCTCACCAGTGC
GCCCGCCGGAGGGTGTTTATCGCGGCTAGAGAGATGTCGCTGCTGCGGTCGCTGCGCGTGTTTCTGGTCGCGCGGACCGGGAGCTACCCG
GCTGGGTCTCTTCTGCGTCAGTCGCCCCAGCCAAGGCACACATTTTATGCTGGGCCCCGTCTGTCTGCCTCGGCCTCCAGCAAGGAGCTC
CTCATGAAGCTGCGGCGGAAAACAGGCTACTCCTTTGTAAATTGCAAGAAAGCTCTGGAGACTTGTGGCGGGGACCTCAAACAGAATTTG
AATACATCTGGCAAGACAACTTCAAGTACAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACAACACAAAATAATAACCAGCAGAAA
AAAGGGATCCAGGTGTTACCTGATGGTCGGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAATTTGGAATGATTGGCCTGTTAACA
TTTATCAGGGCAGCAGAGACAGACCCAGGAATGGTACATCTTGCATTAGGAAGTGACTTAACAACATTAGGCCTCAATCTGAACTCTCCT
GAAAATCTCTACCCCAAATTTGCGTCACCCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGACTTCCATGTTCCATCTGAGTACTTA
ACGAACATTCACATTAGGGATAAGCTGGCTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTCTTCTATCTCTATTACATGAATGGA
GGAGACGTATTACAACTTTTAGCTGCAGTGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAAGAACGAGTATGGATTACCAGGGCA
CCAGGCATGGAGCCAACAATGAAAACCAATACCTATGAGAGGGGAACATATTACTTCTTTGACTGTCTTAACTGGAGGAAAGTAGCTAAG
GAGTTCCATCTGGAATATGACAAATTAGAAGAACGGCCTCACCTGCCATCCACCTTCAACTACAACCCTGCTCAGCAAGCCTTCTAAAAA
AAAAAAAAAAAAAAAAAAAAGACTTCCCTTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAACATAACTGCAGAACTGATGTGGCTC
AGGCACCCTGGTTTTAATTCCTTGAGGATCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGGTCCTGCCTTACTAATTATGTGCTG
CCCAACAACTAAATTTGTAATTTGTTTTTCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATTTCCTTTTTTGCCAGCAGACAGACT
TGAGTCTGTAAAGACAAGCAAATACACTGACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGAAAACCCCCAAAAGACTCAAGAAAA
TTAGACCACAAATTTTGCATTGTTCATTGTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCATTTTTATGTGAAGATCCTTCTCGT
ATTTCATTTGGAAAGATGAGCAAGAGGTCTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAAGGCAGTTTCGCCAAGCTTAATGCA
AGAATATCTGACTGTTTAGAAGAAAGATATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTTATTACTGAGCTTCATCTTTCCAGA
ATGAGCAAAACACTGTCCAGTCTTTGTTACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTTTTGGACATCACATGAATAAAGGTA
TGTATGTACGAATGTGTATATATTATATATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTACCTCATTTTTAGGAGGTGTGCATG
GATGCAATATATGAAAATGGGACATTCTGGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACTAAAAGGGCCAGATTTTCAGCAGCC
AAGGACATCCATACCCAAGTGAATGTGATGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTGGCTGTTTGAACAGCAGCGTTTCAT

>94546_94546_4_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000454289_CNOT2_chr12_70732223_ENST00000418359_length(amino acids)=374AA_BP=134
MCRLKKSSRGEDCVPPASRWHHTRLVRSAGEFWPFRRAVGLLPHQCARRRVFIAAREMSLLRSLRVFLVARTGSYPAGSLLRQSPQPRHT
FYAGPRLSASASSKELLMKLRRKTGYSFVNCKKALETCGGDLKQNLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNI
PQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKL
GRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPH

--------------------------------------------------------------
>94546_94546_5_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000540550_CNOT2_chr12_70732223_ENST00000229195_length(transcript)=2089nt_BP=288nt
GTAGGTTTGTTGCCTCACCAGTGCGCCCGCCGGAGGGTGTTTATCGCGGCTAGAGAGATGTCGCTGCTGCGGTCGCTGCGCGTGTTTCTG
GTCGCGCGGACCGGGAGCTACCCGGCTGGGTCTCTTCTGCGTCAGTCGCCCCAGCCAAGGCACACATTTTATGCTGGGCCCCGTCTGTCT
GCCTCGGCCTCCAGCAAGGAGCTCCTCATGAAGCTGCGGCGGAAAACAGGCTACTCCTTTGTAAATTGCAAGAAAGCTCTGGAGACTTGT
GGCGGGGACCTCAAACAGAATTTGAATACATCTGGCAAGACAACTTCAAGTACAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACA
ACACAAAATAATAACCAGCAGAAAAAAGGGATCCAGGTGTTACCTGATGGTCGGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAA
TTTGGAATGATTGGCCTGTTAACATTTATCAGGGCAGCAGAGACAGACCCAGGAATGGTACATCTTGCATTAGGAAGTGACTTAACAACA
TTAGGCCTCAATCTGAACTCTCCTGAAAATCTCTACCCCAAATTTGCGTCACCCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGAC
TTCCATGTTCCATCTGAGTACTTAACGAACATTCACATTAGGGATAAGCTGGCTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTC
TTCTATCTCTATTACATGAATGGAGGAGACGTATTACAACTTTTAGCTGCAGTGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAA
GAACGAGTATGGATTACCAGGGCACCAGGCATGGAGCCAACAATGAAAACCAATACCTATGAGAGGGGAACATATTACTTCTTTGACTGT
CTTAACTGGAGGAAAGTAGCTAAGGAGTTCCATCTGGAATATGACAAATTAGAAGAACGGCCTCACCTGCCATCCACCTTCAACTACAAC
CCTGCTCAGCAAGCCTTCTAAAAAAAAAAAAAAAAAAAAAAAAAGACTTCCCTTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAAC
ATAACTGCAGAACTGATGTGGCTCAGGCACCCTGGTTTTAATTCCTTGAGGATCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGG
TCCTGCCTTACTAATTATGTGCTGCCCAACAACTAAATTTGTAATTTGTTTTTCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATT
TCCTTTTTTGCCAGCAGACAGACTTGAGTCTGTAAAGACAAGCAAATACACTGACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGA
AAACCCCCAAAAGACTCAAGAAAATTAGACCACAAATTTTGCATTGTTCATTGTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCA
TTTTTATGTGAAGATCCTTCTCGTATTTCATTTGGAAAGATGAGCAAGAGGTCTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAA
GGCAGTTTCGCCAAGCTTAATGCAAGAATATCTGACTGTTTAGAAGAAAGATATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTT
ATTACTGAGCTTCATCTTTCCAGAATGAGCAAAACACTGTCCAGTCTTTGTTACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTT
TTGGACATCACATGAATAAAGGTATGTATGTACGAATGTGTATATATTATATATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTA
CCTCATTTTTAGGAGGTGTGCATGGATGCAATATATGAAAATGGGACATTCTGGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACT
AAAAGGGCCAGATTTTCAGCAGCCAAGGACATCCATACCCAAGTGAATGTGATGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTG
GCTGTTTGAACAGCAGCGTTTCATAGGAAGAGAAAAAAAGATCAATCTTGTATTTTCTGACCACATAAAGGCTTCTTCTCTTTGTAATAA

>94546_94546_5_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000540550_CNOT2_chr12_70732223_ENST00000229195_length(amino acids)=334AA_BP=94
MLPHQCARRRVFIAAREMSLLRSLRVFLVARTGSYPAGSLLRQSPQPRHTFYAGPRLSASASSKELLMKLRRKTGYSFVNCKKALETCGG
DLKQNLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLG
LNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEER

--------------------------------------------------------------
>94546_94546_6_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000540550_CNOT2_chr12_70732223_ENST00000418359_length(transcript)=2089nt_BP=288nt
GTAGGTTTGTTGCCTCACCAGTGCGCCCGCCGGAGGGTGTTTATCGCGGCTAGAGAGATGTCGCTGCTGCGGTCGCTGCGCGTGTTTCTG
GTCGCGCGGACCGGGAGCTACCCGGCTGGGTCTCTTCTGCGTCAGTCGCCCCAGCCAAGGCACACATTTTATGCTGGGCCCCGTCTGTCT
GCCTCGGCCTCCAGCAAGGAGCTCCTCATGAAGCTGCGGCGGAAAACAGGCTACTCCTTTGTAAATTGCAAGAAAGCTCTGGAGACTTGT
GGCGGGGACCTCAAACAGAATTTGAATACATCTGGCAAGACAACTTCAAGTACAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACA
ACACAAAATAATAACCAGCAGAAAAAAGGGATCCAGGTGTTACCTGATGGTCGGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAA
TTTGGAATGATTGGCCTGTTAACATTTATCAGGGCAGCAGAGACAGACCCAGGAATGGTACATCTTGCATTAGGAAGTGACTTAACAACA
TTAGGCCTCAATCTGAACTCTCCTGAAAATCTCTACCCCAAATTTGCGTCACCCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGAC
TTCCATGTTCCATCTGAGTACTTAACGAACATTCACATTAGGGATAAGCTGGCTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTC
TTCTATCTCTATTACATGAATGGAGGAGACGTATTACAACTTTTAGCTGCAGTGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAA
GAACGAGTATGGATTACCAGGGCACCAGGCATGGAGCCAACAATGAAAACCAATACCTATGAGAGGGGAACATATTACTTCTTTGACTGT
CTTAACTGGAGGAAAGTAGCTAAGGAGTTCCATCTGGAATATGACAAATTAGAAGAACGGCCTCACCTGCCATCCACCTTCAACTACAAC
CCTGCTCAGCAAGCCTTCTAAAAAAAAAAAAAAAAAAAAAAAAAGACTTCCCTTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAAC
ATAACTGCAGAACTGATGTGGCTCAGGCACCCTGGTTTTAATTCCTTGAGGATCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGG
TCCTGCCTTACTAATTATGTGCTGCCCAACAACTAAATTTGTAATTTGTTTTTCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATT
TCCTTTTTTGCCAGCAGACAGACTTGAGTCTGTAAAGACAAGCAAATACACTGACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGA
AAACCCCCAAAAGACTCAAGAAAATTAGACCACAAATTTTGCATTGTTCATTGTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCA
TTTTTATGTGAAGATCCTTCTCGTATTTCATTTGGAAAGATGAGCAAGAGGTCTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAA
GGCAGTTTCGCCAAGCTTAATGCAAGAATATCTGACTGTTTAGAAGAAAGATATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTT
ATTACTGAGCTTCATCTTTCCAGAATGAGCAAAACACTGTCCAGTCTTTGTTACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTT
TTGGACATCACATGAATAAAGGTATGTATGTACGAATGTGTATATATTATATATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTA
CCTCATTTTTAGGAGGTGTGCATGGATGCAATATATGAAAATGGGACATTCTGGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACT
AAAAGGGCCAGATTTTCAGCAGCCAAGGACATCCATACCCAAGTGAATGTGATGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTG
GCTGTTTGAACAGCAGCGTTTCATAGGAAGAGAAAAAAAGATCAATCTTGTATTTTCTGACCACATAAAGGCTTCTTCTCTTTGTAATAA

>94546_94546_6_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000540550_CNOT2_chr12_70732223_ENST00000418359_length(amino acids)=334AA_BP=94
MLPHQCARRRVFIAAREMSLLRSLRVFLVARTGSYPAGSLLRQSPQPRHTFYAGPRLSASASSKELLMKLRRKTGYSFVNCKKALETCGG
DLKQNLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLG
LNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEER

--------------------------------------------------------------
>94546_94546_7_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000543727_CNOT2_chr12_70732223_ENST00000229195_length(transcript)=2089nt_BP=288nt
GTAGGTTTGTTGCCTCACCAGTGCGCCCGCCGGAGGGTGTTTATCGCGGCTAGAGAGATGTCGCTGCTGCGGTCGCTGCGCGTGTTTCTG
GTCGCGCGGACCGGGAGCTACCCGGCTGGGTCTCTTCTGCGTCAGTCGCCCCAGCCAAGGCACACATTTTATGCTGGGCCCCGTCTGTCT
GCCTCGGCCTCCAGCAAGGAGCTCCTCATGAAGCTGCGGCGGAAAACAGGCTACTCCTTTGTAAATTGCAAGAAAGCTCTGGAGACTTGT
GGCGGGGACCTCAAACAGAATTTGAATACATCTGGCAAGACAACTTCAAGTACAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACA
ACACAAAATAATAACCAGCAGAAAAAAGGGATCCAGGTGTTACCTGATGGTCGGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAA
TTTGGAATGATTGGCCTGTTAACATTTATCAGGGCAGCAGAGACAGACCCAGGAATGGTACATCTTGCATTAGGAAGTGACTTAACAACA
TTAGGCCTCAATCTGAACTCTCCTGAAAATCTCTACCCCAAATTTGCGTCACCCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGAC
TTCCATGTTCCATCTGAGTACTTAACGAACATTCACATTAGGGATAAGCTGGCTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTC
TTCTATCTCTATTACATGAATGGAGGAGACGTATTACAACTTTTAGCTGCAGTGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAA
GAACGAGTATGGATTACCAGGGCACCAGGCATGGAGCCAACAATGAAAACCAATACCTATGAGAGGGGAACATATTACTTCTTTGACTGT
CTTAACTGGAGGAAAGTAGCTAAGGAGTTCCATCTGGAATATGACAAATTAGAAGAACGGCCTCACCTGCCATCCACCTTCAACTACAAC
CCTGCTCAGCAAGCCTTCTAAAAAAAAAAAAAAAAAAAAAAAAAGACTTCCCTTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAAC
ATAACTGCAGAACTGATGTGGCTCAGGCACCCTGGTTTTAATTCCTTGAGGATCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGG
TCCTGCCTTACTAATTATGTGCTGCCCAACAACTAAATTTGTAATTTGTTTTTCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATT
TCCTTTTTTGCCAGCAGACAGACTTGAGTCTGTAAAGACAAGCAAATACACTGACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGA
AAACCCCCAAAAGACTCAAGAAAATTAGACCACAAATTTTGCATTGTTCATTGTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCA
TTTTTATGTGAAGATCCTTCTCGTATTTCATTTGGAAAGATGAGCAAGAGGTCTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAA
GGCAGTTTCGCCAAGCTTAATGCAAGAATATCTGACTGTTTAGAAGAAAGATATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTT
ATTACTGAGCTTCATCTTTCCAGAATGAGCAAAACACTGTCCAGTCTTTGTTACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTT
TTGGACATCACATGAATAAAGGTATGTATGTACGAATGTGTATATATTATATATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTA
CCTCATTTTTAGGAGGTGTGCATGGATGCAATATATGAAAATGGGACATTCTGGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACT
AAAAGGGCCAGATTTTCAGCAGCCAAGGACATCCATACCCAAGTGAATGTGATGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTG
GCTGTTTGAACAGCAGCGTTTCATAGGAAGAGAAAAAAAGATCAATCTTGTATTTTCTGACCACATAAAGGCTTCTTCTCTTTGTAATAA

>94546_94546_7_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000543727_CNOT2_chr12_70732223_ENST00000229195_length(amino acids)=334AA_BP=94
MLPHQCARRRVFIAAREMSLLRSLRVFLVARTGSYPAGSLLRQSPQPRHTFYAGPRLSASASSKELLMKLRRKTGYSFVNCKKALETCGG
DLKQNLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLG
LNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEER

--------------------------------------------------------------
>94546_94546_8_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000543727_CNOT2_chr12_70732223_ENST00000418359_length(transcript)=2089nt_BP=288nt
GTAGGTTTGTTGCCTCACCAGTGCGCCCGCCGGAGGGTGTTTATCGCGGCTAGAGAGATGTCGCTGCTGCGGTCGCTGCGCGTGTTTCTG
GTCGCGCGGACCGGGAGCTACCCGGCTGGGTCTCTTCTGCGTCAGTCGCCCCAGCCAAGGCACACATTTTATGCTGGGCCCCGTCTGTCT
GCCTCGGCCTCCAGCAAGGAGCTCCTCATGAAGCTGCGGCGGAAAACAGGCTACTCCTTTGTAAATTGCAAGAAAGCTCTGGAGACTTGT
GGCGGGGACCTCAAACAGAATTTGAATACATCTGGCAAGACAACTTCAAGTACAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACA
ACACAAAATAATAACCAGCAGAAAAAAGGGATCCAGGTGTTACCTGATGGTCGGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAA
TTTGGAATGATTGGCCTGTTAACATTTATCAGGGCAGCAGAGACAGACCCAGGAATGGTACATCTTGCATTAGGAAGTGACTTAACAACA
TTAGGCCTCAATCTGAACTCTCCTGAAAATCTCTACCCCAAATTTGCGTCACCCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGAC
TTCCATGTTCCATCTGAGTACTTAACGAACATTCACATTAGGGATAAGCTGGCTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTC
TTCTATCTCTATTACATGAATGGAGGAGACGTATTACAACTTTTAGCTGCAGTGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAA
GAACGAGTATGGATTACCAGGGCACCAGGCATGGAGCCAACAATGAAAACCAATACCTATGAGAGGGGAACATATTACTTCTTTGACTGT
CTTAACTGGAGGAAAGTAGCTAAGGAGTTCCATCTGGAATATGACAAATTAGAAGAACGGCCTCACCTGCCATCCACCTTCAACTACAAC
CCTGCTCAGCAAGCCTTCTAAAAAAAAAAAAAAAAAAAAAAAAAGACTTCCCTTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAAC
ATAACTGCAGAACTGATGTGGCTCAGGCACCCTGGTTTTAATTCCTTGAGGATCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGG
TCCTGCCTTACTAATTATGTGCTGCCCAACAACTAAATTTGTAATTTGTTTTTCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATT
TCCTTTTTTGCCAGCAGACAGACTTGAGTCTGTAAAGACAAGCAAATACACTGACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGA
AAACCCCCAAAAGACTCAAGAAAATTAGACCACAAATTTTGCATTGTTCATTGTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCA
TTTTTATGTGAAGATCCTTCTCGTATTTCATTTGGAAAGATGAGCAAGAGGTCTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAA
GGCAGTTTCGCCAAGCTTAATGCAAGAATATCTGACTGTTTAGAAGAAAGATATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTT
ATTACTGAGCTTCATCTTTCCAGAATGAGCAAAACACTGTCCAGTCTTTGTTACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTT
TTGGACATCACATGAATAAAGGTATGTATGTACGAATGTGTATATATTATATATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTA
CCTCATTTTTAGGAGGTGTGCATGGATGCAATATATGAAAATGGGACATTCTGGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACT
AAAAGGGCCAGATTTTCAGCAGCCAAGGACATCCATACCCAAGTGAATGTGATGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTG
GCTGTTTGAACAGCAGCGTTTCATAGGAAGAGAAAAAAAGATCAATCTTGTATTTTCTGACCACATAAAGGCTTCTTCTCTTTGTAATAA

>94546_94546_8_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000543727_CNOT2_chr12_70732223_ENST00000418359_length(amino acids)=334AA_BP=94
MLPHQCARRRVFIAAREMSLLRSLRVFLVARTGSYPAGSLLRQSPQPRHTFYAGPRLSASASSKELLMKLRRKTGYSFVNCKKALETCGG
DLKQNLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLG
LNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEER

--------------------------------------------------------------
>94546_94546_9_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000548851_CNOT2_chr12_70732223_ENST00000229195_length(transcript)=2047nt_BP=246nt
ATCGCGGCTAGAGAGATGTCGCTGCTGCGGTCGCTGCGCGTGTTTCTGGTCGCGCGGACCGGGAGCTACCCGGCTGGGTCTCTTCTGCGT
CAGTCGCCCCAGCCAAGGCACACATTTTATGCTGGGCCCCGTCTGTCTGCCTCGGCCTCCAGCAAGGAGCTCCTCATGAAGCTGCGGCGG
AAAACAGGCTACTCCTTTGTAAATTGCAAGAAAGCTCTGGAGACTTGTGGCGGGGACCTCAAACAGAATTTGAATACATCTGGCAAGACA
ACTTCAAGTACAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACAACACAAAATAATAACCAGCAGAAAAAAGGGATCCAGGTGTTA
CCTGATGGTCGGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAATTTGGAATGATTGGCCTGTTAACATTTATCAGGGCAGCAGAG
ACAGACCCAGGAATGGTACATCTTGCATTAGGAAGTGACTTAACAACATTAGGCCTCAATCTGAACTCTCCTGAAAATCTCTACCCCAAA
TTTGCGTCACCCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGACTTCCATGTTCCATCTGAGTACTTAACGAACATTCACATTAGG
GATAAGCTGGCTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTCTTCTATCTCTATTACATGAATGGAGGAGACGTATTACAACTT
TTAGCTGCAGTGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAAGAACGAGTATGGATTACCAGGGCACCAGGCATGGAGCCAACA
ATGAAAACCAATACCTATGAGAGGGGAACATATTACTTCTTTGACTGTCTTAACTGGAGGAAAGTAGCTAAGGAGTTCCATCTGGAATAT
GACAAATTAGAAGAACGGCCTCACCTGCCATCCACCTTCAACTACAACCCTGCTCAGCAAGCCTTCTAAAAAAAAAAAAAAAAAAAAAAA
AAGACTTCCCTTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAACATAACTGCAGAACTGATGTGGCTCAGGCACCCTGGTTTTAAT
TCCTTGAGGATCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGGTCCTGCCTTACTAATTATGTGCTGCCCAACAACTAAATTTGT
AATTTGTTTTTCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATTTCCTTTTTTGCCAGCAGACAGACTTGAGTCTGTAAAGACAAG
CAAATACACTGACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGAAAACCCCCAAAAGACTCAAGAAAATTAGACCACAAATTTTGC
ATTGTTCATTGTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCATTTTTATGTGAAGATCCTTCTCGTATTTCATTTGGAAAGATG
AGCAAGAGGTCTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAAGGCAGTTTCGCCAAGCTTAATGCAAGAATATCTGACTGTTTA
GAAGAAAGATATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTTATTACTGAGCTTCATCTTTCCAGAATGAGCAAAACACTGTCC
AGTCTTTGTTACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTTTTGGACATCACATGAATAAAGGTATGTATGTACGAATGTGTA
TATATTATATATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTACCTCATTTTTAGGAGGTGTGCATGGATGCAATATATGAAAAT
GGGACATTCTGGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACTAAAAGGGCCAGATTTTCAGCAGCCAAGGACATCCATACCCAA
GTGAATGTGATGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTGGCTGTTTGAACAGCAGCGTTTCATAGGAAGAGAAAAAAAGAT

>94546_94546_9_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000548851_CNOT2_chr12_70732223_ENST00000229195_length(amino acids)=317AA_BP=77
MSLLRSLRVFLVARTGSYPAGSLLRQSPQPRHTFYAGPRLSASASSKELLMKLRRKTGYSFVNCKKALETCGGDLKQNLNTSGKTTSSTD
GPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPW
ASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNT

--------------------------------------------------------------
>94546_94546_10_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000548851_CNOT2_chr12_70732223_ENST00000418359_length(transcript)=2047nt_BP=246nt
ATCGCGGCTAGAGAGATGTCGCTGCTGCGGTCGCTGCGCGTGTTTCTGGTCGCGCGGACCGGGAGCTACCCGGCTGGGTCTCTTCTGCGT
CAGTCGCCCCAGCCAAGGCACACATTTTATGCTGGGCCCCGTCTGTCTGCCTCGGCCTCCAGCAAGGAGCTCCTCATGAAGCTGCGGCGG
AAAACAGGCTACTCCTTTGTAAATTGCAAGAAAGCTCTGGAGACTTGTGGCGGGGACCTCAAACAGAATTTGAATACATCTGGCAAGACA
ACTTCAAGTACAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACAACACAAAATAATAACCAGCAGAAAAAAGGGATCCAGGTGTTA
CCTGATGGTCGGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAATTTGGAATGATTGGCCTGTTAACATTTATCAGGGCAGCAGAG
ACAGACCCAGGAATGGTACATCTTGCATTAGGAAGTGACTTAACAACATTAGGCCTCAATCTGAACTCTCCTGAAAATCTCTACCCCAAA
TTTGCGTCACCCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGACTTCCATGTTCCATCTGAGTACTTAACGAACATTCACATTAGG
GATAAGCTGGCTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTCTTCTATCTCTATTACATGAATGGAGGAGACGTATTACAACTT
TTAGCTGCAGTGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAAGAACGAGTATGGATTACCAGGGCACCAGGCATGGAGCCAACA
ATGAAAACCAATACCTATGAGAGGGGAACATATTACTTCTTTGACTGTCTTAACTGGAGGAAAGTAGCTAAGGAGTTCCATCTGGAATAT
GACAAATTAGAAGAACGGCCTCACCTGCCATCCACCTTCAACTACAACCCTGCTCAGCAAGCCTTCTAAAAAAAAAAAAAAAAAAAAAAA
AAGACTTCCCTTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAACATAACTGCAGAACTGATGTGGCTCAGGCACCCTGGTTTTAAT
TCCTTGAGGATCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGGTCCTGCCTTACTAATTATGTGCTGCCCAACAACTAAATTTGT
AATTTGTTTTTCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATTTCCTTTTTTGCCAGCAGACAGACTTGAGTCTGTAAAGACAAG
CAAATACACTGACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGAAAACCCCCAAAAGACTCAAGAAAATTAGACCACAAATTTTGC
ATTGTTCATTGTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCATTTTTATGTGAAGATCCTTCTCGTATTTCATTTGGAAAGATG
AGCAAGAGGTCTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAAGGCAGTTTCGCCAAGCTTAATGCAAGAATATCTGACTGTTTA
GAAGAAAGATATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTTATTACTGAGCTTCATCTTTCCAGAATGAGCAAAACACTGTCC
AGTCTTTGTTACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTTTTGGACATCACATGAATAAAGGTATGTATGTACGAATGTGTA
TATATTATATATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTACCTCATTTTTAGGAGGTGTGCATGGATGCAATATATGAAAAT
GGGACATTCTGGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACTAAAAGGGCCAGATTTTCAGCAGCCAAGGACATCCATACCCAA
GTGAATGTGATGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTGGCTGTTTGAACAGCAGCGTTTCATAGGAAGAGAAAAAAAGAT

>94546_94546_10_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000548851_CNOT2_chr12_70732223_ENST00000418359_length(amino acids)=317AA_BP=77
MSLLRSLRVFLVARTGSYPAGSLLRQSPQPRHTFYAGPRLSASASSKELLMKLRRKTGYSFVNCKKALETCGGDLKQNLNTSGKTTSSTD
GPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPW
ASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNT

--------------------------------------------------------------
>94546_94546_11_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000550559_CNOT2_chr12_70732223_ENST00000229195_length(transcript)=2047nt_BP=246nt
ATCGCGGCTAGAGAGATGTCGCTGCTGCGGTCGCTGCGCGTGTTTCTGGTCGCGCGGACCGGGAGCTACCCGGCTGGGTCTCTTCTGCGT
CAGTCGCCCCAGCCAAGGCACACATTTTATGCTGGGCCCCGTCTGTCTGCCTCGGCCTCCAGCAAGGAGCTCCTCATGAAGCTGCGGCGG
AAAACAGGCTACTCCTTTGTAAATTGCAAGAAAGCTCTGGAGACTTGTGGCGGGGACCTCAAACAGAATTTGAATACATCTGGCAAGACA
ACTTCAAGTACAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACAACACAAAATAATAACCAGCAGAAAAAAGGGATCCAGGTGTTA
CCTGATGGTCGGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAATTTGGAATGATTGGCCTGTTAACATTTATCAGGGCAGCAGAG
ACAGACCCAGGAATGGTACATCTTGCATTAGGAAGTGACTTAACAACATTAGGCCTCAATCTGAACTCTCCTGAAAATCTCTACCCCAAA
TTTGCGTCACCCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGACTTCCATGTTCCATCTGAGTACTTAACGAACATTCACATTAGG
GATAAGCTGGCTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTCTTCTATCTCTATTACATGAATGGAGGAGACGTATTACAACTT
TTAGCTGCAGTGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAAGAACGAGTATGGATTACCAGGGCACCAGGCATGGAGCCAACA
ATGAAAACCAATACCTATGAGAGGGGAACATATTACTTCTTTGACTGTCTTAACTGGAGGAAAGTAGCTAAGGAGTTCCATCTGGAATAT
GACAAATTAGAAGAACGGCCTCACCTGCCATCCACCTTCAACTACAACCCTGCTCAGCAAGCCTTCTAAAAAAAAAAAAAAAAAAAAAAA
AAGACTTCCCTTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAACATAACTGCAGAACTGATGTGGCTCAGGCACCCTGGTTTTAAT
TCCTTGAGGATCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGGTCCTGCCTTACTAATTATGTGCTGCCCAACAACTAAATTTGT
AATTTGTTTTTCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATTTCCTTTTTTGCCAGCAGACAGACTTGAGTCTGTAAAGACAAG
CAAATACACTGACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGAAAACCCCCAAAAGACTCAAGAAAATTAGACCACAAATTTTGC
ATTGTTCATTGTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCATTTTTATGTGAAGATCCTTCTCGTATTTCATTTGGAAAGATG
AGCAAGAGGTCTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAAGGCAGTTTCGCCAAGCTTAATGCAAGAATATCTGACTGTTTA
GAAGAAAGATATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTTATTACTGAGCTTCATCTTTCCAGAATGAGCAAAACACTGTCC
AGTCTTTGTTACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTTTTGGACATCACATGAATAAAGGTATGTATGTACGAATGTGTA
TATATTATATATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTACCTCATTTTTAGGAGGTGTGCATGGATGCAATATATGAAAAT
GGGACATTCTGGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACTAAAAGGGCCAGATTTTCAGCAGCCAAGGACATCCATACCCAA
GTGAATGTGATGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTGGCTGTTTGAACAGCAGCGTTTCATAGGAAGAGAAAAAAAGAT

>94546_94546_11_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000550559_CNOT2_chr12_70732223_ENST00000229195_length(amino acids)=317AA_BP=77
MSLLRSLRVFLVARTGSYPAGSLLRQSPQPRHTFYAGPRLSASASSKELLMKLRRKTGYSFVNCKKALETCGGDLKQNLNTSGKTTSSTD
GPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPW
ASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNT

--------------------------------------------------------------
>94546_94546_12_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000550559_CNOT2_chr12_70732223_ENST00000418359_length(transcript)=2047nt_BP=246nt
ATCGCGGCTAGAGAGATGTCGCTGCTGCGGTCGCTGCGCGTGTTTCTGGTCGCGCGGACCGGGAGCTACCCGGCTGGGTCTCTTCTGCGT
CAGTCGCCCCAGCCAAGGCACACATTTTATGCTGGGCCCCGTCTGTCTGCCTCGGCCTCCAGCAAGGAGCTCCTCATGAAGCTGCGGCGG
AAAACAGGCTACTCCTTTGTAAATTGCAAGAAAGCTCTGGAGACTTGTGGCGGGGACCTCAAACAGAATTTGAATACATCTGGCAAGACA
ACTTCAAGTACAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACAACACAAAATAATAACCAGCAGAAAAAAGGGATCCAGGTGTTA
CCTGATGGTCGGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAATTTGGAATGATTGGCCTGTTAACATTTATCAGGGCAGCAGAG
ACAGACCCAGGAATGGTACATCTTGCATTAGGAAGTGACTTAACAACATTAGGCCTCAATCTGAACTCTCCTGAAAATCTCTACCCCAAA
TTTGCGTCACCCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGACTTCCATGTTCCATCTGAGTACTTAACGAACATTCACATTAGG
GATAAGCTGGCTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTCTTCTATCTCTATTACATGAATGGAGGAGACGTATTACAACTT
TTAGCTGCAGTGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAAGAACGAGTATGGATTACCAGGGCACCAGGCATGGAGCCAACA
ATGAAAACCAATACCTATGAGAGGGGAACATATTACTTCTTTGACTGTCTTAACTGGAGGAAAGTAGCTAAGGAGTTCCATCTGGAATAT
GACAAATTAGAAGAACGGCCTCACCTGCCATCCACCTTCAACTACAACCCTGCTCAGCAAGCCTTCTAAAAAAAAAAAAAAAAAAAAAAA
AAGACTTCCCTTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAACATAACTGCAGAACTGATGTGGCTCAGGCACCCTGGTTTTAAT
TCCTTGAGGATCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGGTCCTGCCTTACTAATTATGTGCTGCCCAACAACTAAATTTGT
AATTTGTTTTTCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATTTCCTTTTTTGCCAGCAGACAGACTTGAGTCTGTAAAGACAAG
CAAATACACTGACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGAAAACCCCCAAAAGACTCAAGAAAATTAGACCACAAATTTTGC
ATTGTTCATTGTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCATTTTTATGTGAAGATCCTTCTCGTATTTCATTTGGAAAGATG
AGCAAGAGGTCTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAAGGCAGTTTCGCCAAGCTTAATGCAAGAATATCTGACTGTTTA
GAAGAAAGATATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTTATTACTGAGCTTCATCTTTCCAGAATGAGCAAAACACTGTCC
AGTCTTTGTTACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTTTTGGACATCACATGAATAAAGGTATGTATGTACGAATGTGTA
TATATTATATATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTACCTCATTTTTAGGAGGTGTGCATGGATGCAATATATGAAAAT
GGGACATTCTGGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACTAAAAGGGCCAGATTTTCAGCAGCCAAGGACATCCATACCCAA
GTGAATGTGATGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTGGCTGTTTGAACAGCAGCGTTTCATAGGAAGAGAAAAAAAGAT

>94546_94546_12_TSFM-CNOT2_TSFM_chr12_58177066_ENST00000550559_CNOT2_chr12_70732223_ENST00000418359_length(amino acids)=317AA_BP=77
MSLLRSLRVFLVARTGSYPAGSLLRQSPQPRHTFYAGPRLSASASSKELLMKLRRKTGYSFVNCKKALETCGGDLKQNLNTSGKTTSSTD
GPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPW
ASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TSFM-CNOT2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TSFM-CNOT2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TSFM-CNOT2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource