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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:TSPAN3-ELF1 (FusionGDB2 ID:94754)

Fusion Gene Summary for TSPAN3-ELF1

Fusion gene summary

Fusion gene information	Fusion gene name: TSPAN3-ELF1
	Fusion gene ID: 94754
		Hgene	Tgene
	Gene symbol	TSPAN3	ELF1
	Gene ID	10099	84337
	Gene name	tetraspanin 3	elongation factor 1 homolog
	Synonyms	TM4-A\|TM4SF8\|TSPAN-3	ELF1
	Cytomap	15q24.3	19p13.2
	Type of gene	protein-coding	protein-coding
	Description	tetraspanin-3tetraspan 3tetraspan TM4SFtetraspanin TM4-Atransmembrane 4 superfamily member 8	transcription elongation factor 1 homologELF1 homolog, elongation factor 1elongation factor 1 homolog (ELF1, S. cerevisiae)
	Modification date	20200322	20200313
	UniProtAcc	.	P32519
	Ensembl transtripts involved in fusion gene	ENST00000267970, ENST00000346495, ENST00000424443, ENST00000559494, ENST00000558394, ENST00000558745, ENST00000561277,	ENST00000239882, ENST00000498824, ENST00000442101,
Fusion gene scores	* DoF score	13 X 10 X 7=910	13 X 11 X 5=715
	# samples	14	13
	** MAII score	log2(14/910*10)=-2.70043971814109 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(13/715*10)=-2.4594316186373 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: TSPAN3 [Title/Abstract] AND ELF1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	TSPAN3(77363234)-ELF1(41533152), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across TSPAN3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across ELF1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-BR-4371-01A	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-

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Fusion Gene ORF analysis for TSPAN3-ELF1

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000267970	ENST00000239882	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
5CDS-5UTR	ENST00000267970	ENST00000498824	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
5CDS-5UTR	ENST00000346495	ENST00000239882	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
5CDS-5UTR	ENST00000346495	ENST00000498824	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
5CDS-5UTR	ENST00000424443	ENST00000239882	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
5CDS-5UTR	ENST00000424443	ENST00000498824	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
5CDS-5UTR	ENST00000559494	ENST00000239882	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
5CDS-5UTR	ENST00000559494	ENST00000498824	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
5UTR-3CDS	ENST00000558394	ENST00000442101	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
5UTR-5UTR	ENST00000558394	ENST00000239882	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
5UTR-5UTR	ENST00000558394	ENST00000498824	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
In-frame	ENST00000267970	ENST00000442101	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
In-frame	ENST00000346495	ENST00000442101	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
In-frame	ENST00000424443	ENST00000442101	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
In-frame	ENST00000559494	ENST00000442101	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
intron-3CDS	ENST00000558745	ENST00000442101	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
intron-3CDS	ENST00000561277	ENST00000442101	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
intron-5UTR	ENST00000558745	ENST00000239882	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
intron-5UTR	ENST00000558745	ENST00000498824	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
intron-5UTR	ENST00000561277	ENST00000239882	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-
intron-5UTR	ENST00000561277	ENST00000498824	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000267970	TSPAN3	chr15	77363234	-	ENST00000442101	ELF1	chr13	41533152	-	3558	337	25	2052	675
ENST00000346495	TSPAN3	chr15	77363234	-	ENST00000442101	ELF1	chr13	41533152	-	3439	218	2	1933	643
ENST00000424443	TSPAN3	chr15	77363234	-	ENST00000442101	ELF1	chr13	41533152	-	3439	218	2	1933	643
ENST00000559494	TSPAN3	chr15	77363234	-	ENST00000442101	ELF1	chr13	41533152	-	3364	143	80	1858	592

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000267970	ENST00000442101	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-	0.000456338	0.9995436
ENST00000346495	ENST00000442101	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-	0.000390629	0.9996094
ENST00000424443	ENST00000442101	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-	0.000390629	0.9996094
ENST00000559494	ENST00000442101	TSPAN3	chr15	77363234	-	ELF1	chr13	41533152	-	0.000376196	0.9996238

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Fusion Genomic Features for TSPAN3-ELF1

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TSPAN3-ELF1

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:77363234/chr13:41533152)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	ELF1 P32519
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer. {ECO:0000269\|PubMed:8756667}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000267970

1_11

254.0

Topological domain

Cytoplasmic

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000346495

1_11

229.0

Topological domain

Cytoplasmic

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000424443

1_11

190.0

Topological domain

Cytoplasmic

Tgene

ELF1

chr15:77363234

chr13:41533152

ENST00000239882

75_80

620.0

Compositional bias

Note=Poly-Asp

Tgene

ELF1

chr15:77363234

chr13:41533152

ENST00000442101

75_80

596.0

Compositional bias

Note=Poly-Asp

Tgene

ELF1

chr15:77363234

chr13:41533152

ENST00000239882

208_290

620.0

DNA binding

ETS

Tgene

ELF1

chr15:77363234

chr13:41533152

ENST00000442101

208_290

596.0

DNA binding

ETS

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000267970

107_212

254.0

Topological domain

Extracellular

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000267970

234_253

254.0

Topological domain

Cytoplasmic

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000267970

33_50

254.0

Topological domain

Extracellular

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000267970

72_85

254.0

Topological domain

Cytoplasmic

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000346495

107_212

229.0

Topological domain

Extracellular

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000346495

234_253

229.0

Topological domain

Cytoplasmic

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000346495

33_50

229.0

Topological domain

Extracellular

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000346495

72_85

229.0

Topological domain

Cytoplasmic

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000424443

107_212

190.0

Topological domain

Extracellular

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000424443

234_253

190.0

Topological domain

Cytoplasmic

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000424443

33_50

190.0

Topological domain

Extracellular

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000424443

72_85

190.0

Topological domain

Cytoplasmic

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000267970

12_32

254.0

Transmembrane

Helical

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000267970

213_233

254.0

Transmembrane

Helical

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000267970

51_71

254.0

Transmembrane

Helical

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000267970

86_106

254.0

Transmembrane

Helical

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000346495

12_32

229.0

Transmembrane

Helical

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000346495

213_233

229.0

Transmembrane

Helical

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000346495

51_71

229.0

Transmembrane

Helical

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000346495

86_106

229.0

Transmembrane

Helical

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000424443

12_32

190.0

Transmembrane

Helical

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000424443

213_233

190.0

Transmembrane

Helical

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000424443

51_71

190.0

Transmembrane

Helical

Hgene

TSPAN3

chr15:77363234

chr13:41533152

ENST00000424443

86_106

190.0

Transmembrane

Helical

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Fusion Gene Sequence for TSPAN3-ELF1

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>94754_94754_1_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000267970_ELF1_chr13_41533152_ENST00000442101_length(transcript)=3558nt_BP=337nt
CTGCAGCCTCCGCAGAGGCGATTGGCTGAAGCTACCGGCCGCGTGGGGCGGGACTCGGTTGCCAGGGAGCGGCGCGGGAGCCCTGAGGGG
ACTGCGGCGGCTGCGCGGAGGAGCGAGGCACTTGCTGGGGTCGGGGCTGCGCGACGGCGCAGGGGCTGCGGGGAGCGCCGCGCAGGCCGT
GCAGTTCCTAGCGAGGAGGCGCCGCCGCCATTGCCGCTCTCTCGGTGAGCGCAGCCCCGCTCTCCGGGCCGGGCCTTCGCGGGCCACCGG
CGCCATGGGCCAGTGCGGCATCACCTCCTCCAAGACCGTGCTGGTCTTTCTCAACCTCATCTTCTGGCTTGGTGATCCAGCTATTTTTCC
TGCCGTAATTGTGGAACATGTTCCTGGTGCTGATATTCTCAATAGTTATGCCGGTCTAGCCTGTGTGGAAGAGCCCAATGACATGATTAC
TGAGAGTTCACTGGATGTTGCTGAAGAAGAAATCATAGACGATGATGATGATGACATCACCCTTACAGTTGAAGCTTCTTGTCATGACGG
GGATGAAACAATTGAAACTATTGAGGCTGCTGAGGCACTCCTCAATATGGATTCCCCTGGCCCTATGCTGGATGAAAAACGAATAAATGG
GATTCCTGAAGTGATGGAAACACAGCAGGTGCAAGAAAAATATGCAGACTCACCGGGAGCCTCATCACCAGAACAGCCTAAGAGGAAAAA
AGGAAGAAAAACTAAACCACCACGACCAGATTCCCCAGCCACTACGCCAAATATATCTGTGAAGAAGAAAAACAAAGATGGAAAGGGAAA
CACAATTTATCTTTGGGAGTTTTTACTGGCACTGCTCCAGGACAAGGCTACTTGTCCTAAATACATCAAGTGGACCCAGCGAGAGAAAGG
CATTTTTAAATTGGTGGATTCTAAAGCAGTGTCCAGGTTGTGGGGGAAGCACAAAAACAAACCTGATATGAATTATGAGACCATGGGAAG
AGCACTCAGGTACTATTACCAAAGGGGTATTCTGGCAAAAGTGGAAGGTCAGCGCTTGGTGTATCAGTTTAAAGAAATGCCAAAAGATCT
TATATATATAAATGATGAGGATCCAAGTTCCAGCATAGAGTCTTCAGATCCATCGCTATCTTCATCAGCCACTTCAAATAGGAATCAAAC
CAGCCGGTCGAGAGTATCTTCAAGTCCAGGGGTAAAAGGAGGAGCCACTACAGTTCTAAAACCAGGGAATTCTAAAGCTGCAAAACCCAA
AGATCCTGTGGAAGTTGCACAACCATCAGAAGTTTTGAGGACAGTGCAGCCCACGCAGTCTCCATATCCTACCCAGCTCTTCCGGACTGT
TCATGTAGTACAGCCAGTACAGGCTGTCCCAGAGGGAGAAGCAGCTAGAACCAGTACCATGCAGGATGAAACATTAAATTCTTCCGTTCA
GAGTATTAGGACTATACAGGCTCCAACCCAAGTTCCAGTGGTTGTGTCTCCTAGGAATCAGCAGTTGCATACAGTAACACTCCAAACAGT
GCCACTCACAACAGTTATAGCCAGCACAGATCCATCAGCAGGTACTGGATCTCAGAAGTTTATTTTACAAGCCATTCCATCATCACAGCC
CATGACAGTACTGAAAGAAAATGTCATGCTGCAGTCACAAAAGGCGGGCTCTCCTCCTTCAATTGTCTTGGGCCCTGCCCAGGTTCAGCA
GGTCCTTACTAGCAATGTTCAGACCATTTGCAATGGAACCGTCAGTGTGGCTTCCTCTCCATCCTTCAGTGCTACTGCACCTGTGGTGAC
CTTTTCTCCTCGCAGTTCACAGCTGGTTGCTCACCCACCTGGCACTGTAATCACTTCAGTTATCAAAACTCAAGAAACAAAAACTCTTAC
ACAGGAAGTAGAGAAAAAGGAATCTGAAGATCATTTGAAAGAGAACACTGAGAAAACGGAGCAGCAGCCACAGCCTTATGTGATGGTAGT
GTCCAGTTCCAATGGATTTACTTCTCAGGTAGCTATGAAACAAAACGAACTGCTGGAACCCAACTCTTTTTAGTTAATATACCAAAGCTT
ATGAATAATTGTTTGTTAATTGAACATTTTCAATTATATGCAGACTGACTGATTCTAAGATAAATTCTAAGGAGGTTTCTAATTTTGTAA
TTGTTAAAAATAGAGTTAATTTTGACTTTGTTAGATGAGGGAGGAAAACTCAACTGTTTCTCTTTGTTATCTAAATGTTTCAGAATTCAA
TCGTGAAGGAACAGGCATTTTACACTATGAAGACATTCTTTTGAGATTTTTATTTCAGTTGCTATATCATAAGCATTTTTAAAGTTTCTT
TTCTAATTTTACATTGTATTAGATTTTCTGATTCTTTTGTAAATACAGAACTTAAATAGAAGGCAACAGGAAATTTATATAGGAACTATT
TTCATTCCACTTGTGTAAGTTAAGTCTTGACTCTTTCAAATGCAAAAAACCTATTTTATGCTTTGTTAAAATTATGGTGTCACTTAGATT
GACTTTAGTTGACTGCACTATATAATATAGAACTATGAATATGTAGAATAACATGAAAAATTGGAGGTGCTGGTGGTATGGCTGACCCTG
TTTCAGAAGCAGGATAGTATAAAAGCATCAGCCTAAGAATGGCACTCCCACTAACTAGCTATGTAATCTTGACCTCTTTGGGCTTTAGTT
CCTCTCATAAAAGGAAGAGATGTATTGGATTAGACTAGATGATCACCACTTTCTCTTCTAGTTCTAATTTTTTTAATTCTAATACCTATA
TTTTCAAGTTATGTCAATTAAATCATTATCAGGTTATTTCCTAATGTAAGAATAGCTAAAATGTTGCAGAGAAATAAGTGACCCAACAAA
ATTTATTCATCTGTTATGGGTAAGATCTGCCATAAATTCTTCCTAAATAATTTGTTTACTAACTCTTTAGGCCACTGTGCTTTGCGGTCC
ATTAGTAAACTTGTGTTGCTAAGTGCTAAACAGAATACTGCTATTTTGAGAGAGTCAAGACTCTTTCTTAAGGGCCAAGAAAGCAACTTG
AGCCTTGGGCTAATCTGGCTGAGTAGTCAGTTATAAAAGCATAATTGCTTTATATTTTGGATCATTTTTTACTGGGGGCGGACTTGGGGG
GGGTTGCATACAAAGATAACATATATATCCAACTTTCTGAAATGAAATGTTTTTAGATTACTTTTTCAACTGTAAATAATGTACATTTAA
TGTCACAAGAAAAAAATGTCTTCTGCAAATTTTCTAGTATAACAGAAATTTTTGTAGATGAAAAAAATCATTATGTTTAGAGGTCTAATG
CTATGTTTTCATATTACAGAGTGAATTTGTATTTAAACAAAAATTTAAATTTTGGAATCCTCTAAACATTTTTGTATCTTTAATTGGTTT
ATTATTAAATAAATCATATAAAAATTCTCAGTGTCTGTTTTCAGGCAAAAGTTTCTTAAAGAATAAGTGTGCAGAGAATATTACTAGAAC

>94754_94754_1_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000267970_ELF1_chr13_41533152_ENST00000442101_length(amino acids)=675AA_BP=104
MKLPAAWGGTRLPGSGAGALRGLRRLRGGARHLLGSGLRDGAGAAGSAAQAVQFLARRRRRHCRSLGERSPALRAGPSRATGAMGQCGIT
SSKTVLVFLNLIFWLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHDGDETIETIE
AAEALLNMDSPGPMLDEKRINGIPEVMETQQVQEKYADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFL
LALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYINDEDP
SSSIESSDPSLSSSATSNRNQTSRSRVSSSPGVKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYPTQLFRTVHVVQPVQA
VPEGEAARTSTMQDETLNSSVQSIRTIQAPTQVPVVVSPRNQQLHTVTLQTVPLTTVIASTDPSAGTGSQKFILQAIPSSQPMTVLKENV
MLQSQKAGSPPSIVLGPAQVQQVLTSNVQTICNGTVSVASSPSFSATAPVVTFSPRSSQLVAHPPGTVITSVIKTQETKTLTQEVEKKES

--------------------------------------------------------------
>94754_94754_2_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000346495_ELF1_chr13_41533152_ENST00000442101_length(transcript)=3439nt_BP=218nt
ACTTGCTGGGGTCGGGGCTGCGCGACGGCGCAGGGGCTGCGGGGAGCGCCGCGCAGGCCGTGCAGTTCCTAGCGAGGAGGCGCCGCCGCC
ATTGCCGCTCTCTCGGTGAGCGCAGCCCCGCTCTCCGGGCCGGGCCTTCGCGGGCCACCGGCGCCATGGGCCAGTGCGGCATCACCTCCT
CCAAGACCGTGCTGGTCTTTCTCAACCTCATCTTCTGGCTTGGTGATCCAGCTATTTTTCCTGCCGTAATTGTGGAACATGTTCCTGGTG
CTGATATTCTCAATAGTTATGCCGGTCTAGCCTGTGTGGAAGAGCCCAATGACATGATTACTGAGAGTTCACTGGATGTTGCTGAAGAAG
AAATCATAGACGATGATGATGATGACATCACCCTTACAGTTGAAGCTTCTTGTCATGACGGGGATGAAACAATTGAAACTATTGAGGCTG
CTGAGGCACTCCTCAATATGGATTCCCCTGGCCCTATGCTGGATGAAAAACGAATAAATGGGATTCCTGAAGTGATGGAAACACAGCAGG
TGCAAGAAAAATATGCAGACTCACCGGGAGCCTCATCACCAGAACAGCCTAAGAGGAAAAAAGGAAGAAAAACTAAACCACCACGACCAG
ATTCCCCAGCCACTACGCCAAATATATCTGTGAAGAAGAAAAACAAAGATGGAAAGGGAAACACAATTTATCTTTGGGAGTTTTTACTGG
CACTGCTCCAGGACAAGGCTACTTGTCCTAAATACATCAAGTGGACCCAGCGAGAGAAAGGCATTTTTAAATTGGTGGATTCTAAAGCAG
TGTCCAGGTTGTGGGGGAAGCACAAAAACAAACCTGATATGAATTATGAGACCATGGGAAGAGCACTCAGGTACTATTACCAAAGGGGTA
TTCTGGCAAAAGTGGAAGGTCAGCGCTTGGTGTATCAGTTTAAAGAAATGCCAAAAGATCTTATATATATAAATGATGAGGATCCAAGTT
CCAGCATAGAGTCTTCAGATCCATCGCTATCTTCATCAGCCACTTCAAATAGGAATCAAACCAGCCGGTCGAGAGTATCTTCAAGTCCAG
GGGTAAAAGGAGGAGCCACTACAGTTCTAAAACCAGGGAATTCTAAAGCTGCAAAACCCAAAGATCCTGTGGAAGTTGCACAACCATCAG
AAGTTTTGAGGACAGTGCAGCCCACGCAGTCTCCATATCCTACCCAGCTCTTCCGGACTGTTCATGTAGTACAGCCAGTACAGGCTGTCC
CAGAGGGAGAAGCAGCTAGAACCAGTACCATGCAGGATGAAACATTAAATTCTTCCGTTCAGAGTATTAGGACTATACAGGCTCCAACCC
AAGTTCCAGTGGTTGTGTCTCCTAGGAATCAGCAGTTGCATACAGTAACACTCCAAACAGTGCCACTCACAACAGTTATAGCCAGCACAG
ATCCATCAGCAGGTACTGGATCTCAGAAGTTTATTTTACAAGCCATTCCATCATCACAGCCCATGACAGTACTGAAAGAAAATGTCATGC
TGCAGTCACAAAAGGCGGGCTCTCCTCCTTCAATTGTCTTGGGCCCTGCCCAGGTTCAGCAGGTCCTTACTAGCAATGTTCAGACCATTT
GCAATGGAACCGTCAGTGTGGCTTCCTCTCCATCCTTCAGTGCTACTGCACCTGTGGTGACCTTTTCTCCTCGCAGTTCACAGCTGGTTG
CTCACCCACCTGGCACTGTAATCACTTCAGTTATCAAAACTCAAGAAACAAAAACTCTTACACAGGAAGTAGAGAAAAAGGAATCTGAAG
ATCATTTGAAAGAGAACACTGAGAAAACGGAGCAGCAGCCACAGCCTTATGTGATGGTAGTGTCCAGTTCCAATGGATTTACTTCTCAGG
TAGCTATGAAACAAAACGAACTGCTGGAACCCAACTCTTTTTAGTTAATATACCAAAGCTTATGAATAATTGTTTGTTAATTGAACATTT
TCAATTATATGCAGACTGACTGATTCTAAGATAAATTCTAAGGAGGTTTCTAATTTTGTAATTGTTAAAAATAGAGTTAATTTTGACTTT
GTTAGATGAGGGAGGAAAACTCAACTGTTTCTCTTTGTTATCTAAATGTTTCAGAATTCAATCGTGAAGGAACAGGCATTTTACACTATG
AAGACATTCTTTTGAGATTTTTATTTCAGTTGCTATATCATAAGCATTTTTAAAGTTTCTTTTCTAATTTTACATTGTATTAGATTTTCT
GATTCTTTTGTAAATACAGAACTTAAATAGAAGGCAACAGGAAATTTATATAGGAACTATTTTCATTCCACTTGTGTAAGTTAAGTCTTG
ACTCTTTCAAATGCAAAAAACCTATTTTATGCTTTGTTAAAATTATGGTGTCACTTAGATTGACTTTAGTTGACTGCACTATATAATATA
GAACTATGAATATGTAGAATAACATGAAAAATTGGAGGTGCTGGTGGTATGGCTGACCCTGTTTCAGAAGCAGGATAGTATAAAAGCATC
AGCCTAAGAATGGCACTCCCACTAACTAGCTATGTAATCTTGACCTCTTTGGGCTTTAGTTCCTCTCATAAAAGGAAGAGATGTATTGGA
TTAGACTAGATGATCACCACTTTCTCTTCTAGTTCTAATTTTTTTAATTCTAATACCTATATTTTCAAGTTATGTCAATTAAATCATTAT
CAGGTTATTTCCTAATGTAAGAATAGCTAAAATGTTGCAGAGAAATAAGTGACCCAACAAAATTTATTCATCTGTTATGGGTAAGATCTG
CCATAAATTCTTCCTAAATAATTTGTTTACTAACTCTTTAGGCCACTGTGCTTTGCGGTCCATTAGTAAACTTGTGTTGCTAAGTGCTAA
ACAGAATACTGCTATTTTGAGAGAGTCAAGACTCTTTCTTAAGGGCCAAGAAAGCAACTTGAGCCTTGGGCTAATCTGGCTGAGTAGTCA
GTTATAAAAGCATAATTGCTTTATATTTTGGATCATTTTTTACTGGGGGCGGACTTGGGGGGGGTTGCATACAAAGATAACATATATATC
CAACTTTCTGAAATGAAATGTTTTTAGATTACTTTTTCAACTGTAAATAATGTACATTTAATGTCACAAGAAAAAAATGTCTTCTGCAAA
TTTTCTAGTATAACAGAAATTTTTGTAGATGAAAAAAATCATTATGTTTAGAGGTCTAATGCTATGTTTTCATATTACAGAGTGAATTTG
TATTTAAACAAAAATTTAAATTTTGGAATCCTCTAAACATTTTTGTATCTTTAATTGGTTTATTATTAAATAAATCATATAAAAATTCTC
AGTGTCTGTTTTCAGGCAAAAGTTTCTTAAAGAATAAGTGTGCAGAGAATATTACTAGAACATCAGCATTACTTAATGTTTATAAATAAA

>94754_94754_2_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000346495_ELF1_chr13_41533152_ENST00000442101_length(amino acids)=643AA_BP=72
LLGSGLRDGAGAAGSAAQAVQFLARRRRRHCRSLGERSPALRAGPSRATGAMGQCGITSSKTVLVFLNLIFWLGDPAIFPAVIVEHVPGA
DILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHDGDETIETIEAAEALLNMDSPGPMLDEKRINGIPEVMETQQV
QEKYADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAV
SRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYINDEDPSSSIESSDPSLSSSATSNRNQTSRSRVSSSPG
VKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYPTQLFRTVHVVQPVQAVPEGEAARTSTMQDETLNSSVQSIRTIQAPTQ
VPVVVSPRNQQLHTVTLQTVPLTTVIASTDPSAGTGSQKFILQAIPSSQPMTVLKENVMLQSQKAGSPPSIVLGPAQVQQVLTSNVQTIC
NGTVSVASSPSFSATAPVVTFSPRSSQLVAHPPGTVITSVIKTQETKTLTQEVEKKESEDHLKENTEKTEQQPQPYVMVVSSSNGFTSQV

--------------------------------------------------------------
>94754_94754_3_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000424443_ELF1_chr13_41533152_ENST00000442101_length(transcript)=3439nt_BP=218nt
ACTTGCTGGGGTCGGGGCTGCGCGACGGCGCAGGGGCTGCGGGGAGCGCCGCGCAGGCCGTGCAGTTCCTAGCGAGGAGGCGCCGCCGCC
ATTGCCGCTCTCTCGGTGAGCGCAGCCCCGCTCTCCGGGCCGGGCCTTCGCGGGCCACCGGCGCCATGGGCCAGTGCGGCATCACCTCCT
CCAAGACCGTGCTGGTCTTTCTCAACCTCATCTTCTGGCTTGGTGATCCAGCTATTTTTCCTGCCGTAATTGTGGAACATGTTCCTGGTG
CTGATATTCTCAATAGTTATGCCGGTCTAGCCTGTGTGGAAGAGCCCAATGACATGATTACTGAGAGTTCACTGGATGTTGCTGAAGAAG
AAATCATAGACGATGATGATGATGACATCACCCTTACAGTTGAAGCTTCTTGTCATGACGGGGATGAAACAATTGAAACTATTGAGGCTG
CTGAGGCACTCCTCAATATGGATTCCCCTGGCCCTATGCTGGATGAAAAACGAATAAATGGGATTCCTGAAGTGATGGAAACACAGCAGG
TGCAAGAAAAATATGCAGACTCACCGGGAGCCTCATCACCAGAACAGCCTAAGAGGAAAAAAGGAAGAAAAACTAAACCACCACGACCAG
ATTCCCCAGCCACTACGCCAAATATATCTGTGAAGAAGAAAAACAAAGATGGAAAGGGAAACACAATTTATCTTTGGGAGTTTTTACTGG
CACTGCTCCAGGACAAGGCTACTTGTCCTAAATACATCAAGTGGACCCAGCGAGAGAAAGGCATTTTTAAATTGGTGGATTCTAAAGCAG
TGTCCAGGTTGTGGGGGAAGCACAAAAACAAACCTGATATGAATTATGAGACCATGGGAAGAGCACTCAGGTACTATTACCAAAGGGGTA
TTCTGGCAAAAGTGGAAGGTCAGCGCTTGGTGTATCAGTTTAAAGAAATGCCAAAAGATCTTATATATATAAATGATGAGGATCCAAGTT
CCAGCATAGAGTCTTCAGATCCATCGCTATCTTCATCAGCCACTTCAAATAGGAATCAAACCAGCCGGTCGAGAGTATCTTCAAGTCCAG
GGGTAAAAGGAGGAGCCACTACAGTTCTAAAACCAGGGAATTCTAAAGCTGCAAAACCCAAAGATCCTGTGGAAGTTGCACAACCATCAG
AAGTTTTGAGGACAGTGCAGCCCACGCAGTCTCCATATCCTACCCAGCTCTTCCGGACTGTTCATGTAGTACAGCCAGTACAGGCTGTCC
CAGAGGGAGAAGCAGCTAGAACCAGTACCATGCAGGATGAAACATTAAATTCTTCCGTTCAGAGTATTAGGACTATACAGGCTCCAACCC
AAGTTCCAGTGGTTGTGTCTCCTAGGAATCAGCAGTTGCATACAGTAACACTCCAAACAGTGCCACTCACAACAGTTATAGCCAGCACAG
ATCCATCAGCAGGTACTGGATCTCAGAAGTTTATTTTACAAGCCATTCCATCATCACAGCCCATGACAGTACTGAAAGAAAATGTCATGC
TGCAGTCACAAAAGGCGGGCTCTCCTCCTTCAATTGTCTTGGGCCCTGCCCAGGTTCAGCAGGTCCTTACTAGCAATGTTCAGACCATTT
GCAATGGAACCGTCAGTGTGGCTTCCTCTCCATCCTTCAGTGCTACTGCACCTGTGGTGACCTTTTCTCCTCGCAGTTCACAGCTGGTTG
CTCACCCACCTGGCACTGTAATCACTTCAGTTATCAAAACTCAAGAAACAAAAACTCTTACACAGGAAGTAGAGAAAAAGGAATCTGAAG
ATCATTTGAAAGAGAACACTGAGAAAACGGAGCAGCAGCCACAGCCTTATGTGATGGTAGTGTCCAGTTCCAATGGATTTACTTCTCAGG
TAGCTATGAAACAAAACGAACTGCTGGAACCCAACTCTTTTTAGTTAATATACCAAAGCTTATGAATAATTGTTTGTTAATTGAACATTT
TCAATTATATGCAGACTGACTGATTCTAAGATAAATTCTAAGGAGGTTTCTAATTTTGTAATTGTTAAAAATAGAGTTAATTTTGACTTT
GTTAGATGAGGGAGGAAAACTCAACTGTTTCTCTTTGTTATCTAAATGTTTCAGAATTCAATCGTGAAGGAACAGGCATTTTACACTATG
AAGACATTCTTTTGAGATTTTTATTTCAGTTGCTATATCATAAGCATTTTTAAAGTTTCTTTTCTAATTTTACATTGTATTAGATTTTCT
GATTCTTTTGTAAATACAGAACTTAAATAGAAGGCAACAGGAAATTTATATAGGAACTATTTTCATTCCACTTGTGTAAGTTAAGTCTTG
ACTCTTTCAAATGCAAAAAACCTATTTTATGCTTTGTTAAAATTATGGTGTCACTTAGATTGACTTTAGTTGACTGCACTATATAATATA
GAACTATGAATATGTAGAATAACATGAAAAATTGGAGGTGCTGGTGGTATGGCTGACCCTGTTTCAGAAGCAGGATAGTATAAAAGCATC
AGCCTAAGAATGGCACTCCCACTAACTAGCTATGTAATCTTGACCTCTTTGGGCTTTAGTTCCTCTCATAAAAGGAAGAGATGTATTGGA
TTAGACTAGATGATCACCACTTTCTCTTCTAGTTCTAATTTTTTTAATTCTAATACCTATATTTTCAAGTTATGTCAATTAAATCATTAT
CAGGTTATTTCCTAATGTAAGAATAGCTAAAATGTTGCAGAGAAATAAGTGACCCAACAAAATTTATTCATCTGTTATGGGTAAGATCTG
CCATAAATTCTTCCTAAATAATTTGTTTACTAACTCTTTAGGCCACTGTGCTTTGCGGTCCATTAGTAAACTTGTGTTGCTAAGTGCTAA
ACAGAATACTGCTATTTTGAGAGAGTCAAGACTCTTTCTTAAGGGCCAAGAAAGCAACTTGAGCCTTGGGCTAATCTGGCTGAGTAGTCA
GTTATAAAAGCATAATTGCTTTATATTTTGGATCATTTTTTACTGGGGGCGGACTTGGGGGGGGTTGCATACAAAGATAACATATATATC
CAACTTTCTGAAATGAAATGTTTTTAGATTACTTTTTCAACTGTAAATAATGTACATTTAATGTCACAAGAAAAAAATGTCTTCTGCAAA
TTTTCTAGTATAACAGAAATTTTTGTAGATGAAAAAAATCATTATGTTTAGAGGTCTAATGCTATGTTTTCATATTACAGAGTGAATTTG
TATTTAAACAAAAATTTAAATTTTGGAATCCTCTAAACATTTTTGTATCTTTAATTGGTTTATTATTAAATAAATCATATAAAAATTCTC
AGTGTCTGTTTTCAGGCAAAAGTTTCTTAAAGAATAAGTGTGCAGAGAATATTACTAGAACATCAGCATTACTTAATGTTTATAAATAAA

>94754_94754_3_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000424443_ELF1_chr13_41533152_ENST00000442101_length(amino acids)=643AA_BP=72
LLGSGLRDGAGAAGSAAQAVQFLARRRRRHCRSLGERSPALRAGPSRATGAMGQCGITSSKTVLVFLNLIFWLGDPAIFPAVIVEHVPGA
DILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHDGDETIETIEAAEALLNMDSPGPMLDEKRINGIPEVMETQQV
QEKYADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAV
SRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYINDEDPSSSIESSDPSLSSSATSNRNQTSRSRVSSSPG
VKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYPTQLFRTVHVVQPVQAVPEGEAARTSTMQDETLNSSVQSIRTIQAPTQ
VPVVVSPRNQQLHTVTLQTVPLTTVIASTDPSAGTGSQKFILQAIPSSQPMTVLKENVMLQSQKAGSPPSIVLGPAQVQQVLTSNVQTIC
NGTVSVASSPSFSATAPVVTFSPRSSQLVAHPPGTVITSVIKTQETKTLTQEVEKKESEDHLKENTEKTEQQPQPYVMVVSSSNGFTSQV

--------------------------------------------------------------
>94754_94754_4_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000559494_ELF1_chr13_41533152_ENST00000442101_length(transcript)=3364nt_BP=143nt
GGAGGCGCCGCCGCCATTGCCGCTCTCTCGGTGAGCGCAGCCCCGCTCTCCGGGCCGGGCCTTCGCGGGCCACCGGCGCCATGGGCCAGT
GCGGCATCACCTCCTCCAAGACCGTGCTGGTCTTTCTCAACCTCATCTTCTGGCTTGGTGATCCAGCTATTTTTCCTGCCGTAATTGTGG
AACATGTTCCTGGTGCTGATATTCTCAATAGTTATGCCGGTCTAGCCTGTGTGGAAGAGCCCAATGACATGATTACTGAGAGTTCACTGG
ATGTTGCTGAAGAAGAAATCATAGACGATGATGATGATGACATCACCCTTACAGTTGAAGCTTCTTGTCATGACGGGGATGAAACAATTG
AAACTATTGAGGCTGCTGAGGCACTCCTCAATATGGATTCCCCTGGCCCTATGCTGGATGAAAAACGAATAAATGGGATTCCTGAAGTGA
TGGAAACACAGCAGGTGCAAGAAAAATATGCAGACTCACCGGGAGCCTCATCACCAGAACAGCCTAAGAGGAAAAAAGGAAGAAAAACTA
AACCACCACGACCAGATTCCCCAGCCACTACGCCAAATATATCTGTGAAGAAGAAAAACAAAGATGGAAAGGGAAACACAATTTATCTTT
GGGAGTTTTTACTGGCACTGCTCCAGGACAAGGCTACTTGTCCTAAATACATCAAGTGGACCCAGCGAGAGAAAGGCATTTTTAAATTGG
TGGATTCTAAAGCAGTGTCCAGGTTGTGGGGGAAGCACAAAAACAAACCTGATATGAATTATGAGACCATGGGAAGAGCACTCAGGTACT
ATTACCAAAGGGGTATTCTGGCAAAAGTGGAAGGTCAGCGCTTGGTGTATCAGTTTAAAGAAATGCCAAAAGATCTTATATATATAAATG
ATGAGGATCCAAGTTCCAGCATAGAGTCTTCAGATCCATCGCTATCTTCATCAGCCACTTCAAATAGGAATCAAACCAGCCGGTCGAGAG
TATCTTCAAGTCCAGGGGTAAAAGGAGGAGCCACTACAGTTCTAAAACCAGGGAATTCTAAAGCTGCAAAACCCAAAGATCCTGTGGAAG
TTGCACAACCATCAGAAGTTTTGAGGACAGTGCAGCCCACGCAGTCTCCATATCCTACCCAGCTCTTCCGGACTGTTCATGTAGTACAGC
CAGTACAGGCTGTCCCAGAGGGAGAAGCAGCTAGAACCAGTACCATGCAGGATGAAACATTAAATTCTTCCGTTCAGAGTATTAGGACTA
TACAGGCTCCAACCCAAGTTCCAGTGGTTGTGTCTCCTAGGAATCAGCAGTTGCATACAGTAACACTCCAAACAGTGCCACTCACAACAG
TTATAGCCAGCACAGATCCATCAGCAGGTACTGGATCTCAGAAGTTTATTTTACAAGCCATTCCATCATCACAGCCCATGACAGTACTGA
AAGAAAATGTCATGCTGCAGTCACAAAAGGCGGGCTCTCCTCCTTCAATTGTCTTGGGCCCTGCCCAGGTTCAGCAGGTCCTTACTAGCA
ATGTTCAGACCATTTGCAATGGAACCGTCAGTGTGGCTTCCTCTCCATCCTTCAGTGCTACTGCACCTGTGGTGACCTTTTCTCCTCGCA
GTTCACAGCTGGTTGCTCACCCACCTGGCACTGTAATCACTTCAGTTATCAAAACTCAAGAAACAAAAACTCTTACACAGGAAGTAGAGA
AAAAGGAATCTGAAGATCATTTGAAAGAGAACACTGAGAAAACGGAGCAGCAGCCACAGCCTTATGTGATGGTAGTGTCCAGTTCCAATG
GATTTACTTCTCAGGTAGCTATGAAACAAAACGAACTGCTGGAACCCAACTCTTTTTAGTTAATATACCAAAGCTTATGAATAATTGTTT
GTTAATTGAACATTTTCAATTATATGCAGACTGACTGATTCTAAGATAAATTCTAAGGAGGTTTCTAATTTTGTAATTGTTAAAAATAGA
GTTAATTTTGACTTTGTTAGATGAGGGAGGAAAACTCAACTGTTTCTCTTTGTTATCTAAATGTTTCAGAATTCAATCGTGAAGGAACAG
GCATTTTACACTATGAAGACATTCTTTTGAGATTTTTATTTCAGTTGCTATATCATAAGCATTTTTAAAGTTTCTTTTCTAATTTTACAT
TGTATTAGATTTTCTGATTCTTTTGTAAATACAGAACTTAAATAGAAGGCAACAGGAAATTTATATAGGAACTATTTTCATTCCACTTGT
GTAAGTTAAGTCTTGACTCTTTCAAATGCAAAAAACCTATTTTATGCTTTGTTAAAATTATGGTGTCACTTAGATTGACTTTAGTTGACT
GCACTATATAATATAGAACTATGAATATGTAGAATAACATGAAAAATTGGAGGTGCTGGTGGTATGGCTGACCCTGTTTCAGAAGCAGGA
TAGTATAAAAGCATCAGCCTAAGAATGGCACTCCCACTAACTAGCTATGTAATCTTGACCTCTTTGGGCTTTAGTTCCTCTCATAAAAGG
AAGAGATGTATTGGATTAGACTAGATGATCACCACTTTCTCTTCTAGTTCTAATTTTTTTAATTCTAATACCTATATTTTCAAGTTATGT
CAATTAAATCATTATCAGGTTATTTCCTAATGTAAGAATAGCTAAAATGTTGCAGAGAAATAAGTGACCCAACAAAATTTATTCATCTGT
TATGGGTAAGATCTGCCATAAATTCTTCCTAAATAATTTGTTTACTAACTCTTTAGGCCACTGTGCTTTGCGGTCCATTAGTAAACTTGT
GTTGCTAAGTGCTAAACAGAATACTGCTATTTTGAGAGAGTCAAGACTCTTTCTTAAGGGCCAAGAAAGCAACTTGAGCCTTGGGCTAAT
CTGGCTGAGTAGTCAGTTATAAAAGCATAATTGCTTTATATTTTGGATCATTTTTTACTGGGGGCGGACTTGGGGGGGGTTGCATACAAA
GATAACATATATATCCAACTTTCTGAAATGAAATGTTTTTAGATTACTTTTTCAACTGTAAATAATGTACATTTAATGTCACAAGAAAAA
AATGTCTTCTGCAAATTTTCTAGTATAACAGAAATTTTTGTAGATGAAAAAAATCATTATGTTTAGAGGTCTAATGCTATGTTTTCATAT
TACAGAGTGAATTTGTATTTAAACAAAAATTTAAATTTTGGAATCCTCTAAACATTTTTGTATCTTTAATTGGTTTATTATTAAATAAAT
CATATAAAAATTCTCAGTGTCTGTTTTCAGGCAAAAGTTTCTTAAAGAATAAGTGTGCAGAGAATATTACTAGAACATCAGCATTACTTA

>94754_94754_4_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000559494_ELF1_chr13_41533152_ENST00000442101_length(amino acids)=592AA_BP=21
MGQCGITSSKTVLVFLNLIFWLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHDGD
ETIETIEAAEALLNMDSPGPMLDEKRINGIPEVMETQQVQEKYADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNT
IYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLI
YINDEDPSSSIESSDPSLSSSATSNRNQTSRSRVSSSPGVKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYPTQLFRTVH
VVQPVQAVPEGEAARTSTMQDETLNSSVQSIRTIQAPTQVPVVVSPRNQQLHTVTLQTVPLTTVIASTDPSAGTGSQKFILQAIPSSQPM
TVLKENVMLQSQKAGSPPSIVLGPAQVQQVLTSNVQTICNGTVSVASSPSFSATAPVVTFSPRSSQLVAHPPGTVITSVIKTQETKTLTQ

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for TSPAN3-ELF1

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for TSPAN3-ELF1

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for TSPAN3-ELF1

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source