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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TTC28-PITPNB (FusionGDB2 ID:94989)

Fusion Gene Summary for TTC28-PITPNB

check button Fusion gene summary
Fusion gene informationFusion gene name: TTC28-PITPNB
Fusion gene ID: 94989
HgeneTgene
Gene symbol

TTC28

PITPNB

Gene ID

23331

23760

Gene nametetratricopeptide repeat domain 28phosphatidylinositol transfer protein beta
SynonymsTPRBKPI-TP-beta|PtdInsTP|VIB1B
Cytomap

22q12.1

22q12.1

Type of geneprotein-codingprotein-coding
Descriptiontetratricopeptide repeat protein 28TPR repeat protein 28TPR repeat-containing big gene cloned at KeioTPR-containing big gene cloned at Keiophosphatidylinositol transfer protein beta isoformPtdIns transfer protein betaphosphotidylinositol transfer protein, beta
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000397906, ENST00000490475, 
ENST00000320996, ENST00000335272, 
ENST00000455418, 
Fusion gene scores* DoF score46 X 33 X 13=197347 X 8 X 7=392
# samples 5310
** MAII scorelog2(53/19734*10)=-5.218547244106
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/392*10)=-1.97085365434048
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TTC28 [Title/Abstract] AND PITPNB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTTC28(29025539)-PITPNB(28269803), # samples:1
TTC28(28385866)-PITPNB(28269803), # samples:1
TTC28(29025540)-PITPNB(28269803), # samples:1
TTC28(29025540)-PITPNB(28256229), # samples:1
Anticipated loss of major functional domain due to fusion event.TTC28-PITPNB seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePITPNB

GO:0015914

phospholipid transport

16274224


check buttonFusion gene breakpoints across TTC28 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PITPNB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CESCTCGA-HM-A6W2-01ATTC28chr22

28385866

-PITPNBchr22

28269803

-
ChimerDB4LIHCTCGA-DD-A1EB-01ATTC28chr22

29025540

-PITPNBchr22

28269803

-
ChimerDB4LIHCTCGA-DD-A1EBTTC28chr22

29025539

-PITPNBchr22

28269803

-
ChimerDB4LUSCTCGA-77-7141TTC28chr22

29025540

-PITPNBchr22

28256229

-


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Fusion Gene ORF analysis for TTC28-PITPNB

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000397906ENST00000320996TTC28chr22

28385866

-PITPNBchr22

28269803

-
Frame-shiftENST00000397906ENST00000335272TTC28chr22

28385866

-PITPNBchr22

28269803

-
Frame-shiftENST00000397906ENST00000455418TTC28chr22

28385866

-PITPNBchr22

28269803

-
In-frameENST00000397906ENST00000320996TTC28chr22

29025540

-PITPNBchr22

28269803

-
In-frameENST00000397906ENST00000320996TTC28chr22

29025539

-PITPNBchr22

28269803

-
In-frameENST00000397906ENST00000320996TTC28chr22

29025540

-PITPNBchr22

28256229

-
In-frameENST00000397906ENST00000335272TTC28chr22

29025540

-PITPNBchr22

28269803

-
In-frameENST00000397906ENST00000335272TTC28chr22

29025539

-PITPNBchr22

28269803

-
In-frameENST00000397906ENST00000335272TTC28chr22

29025540

-PITPNBchr22

28256229

-
In-frameENST00000397906ENST00000455418TTC28chr22

29025540

-PITPNBchr22

28269803

-
In-frameENST00000397906ENST00000455418TTC28chr22

29025539

-PITPNBchr22

28269803

-
In-frameENST00000397906ENST00000455418TTC28chr22

29025540

-PITPNBchr22

28256229

-
intron-3CDSENST00000490475ENST00000320996TTC28chr22

28385866

-PITPNBchr22

28269803

-
intron-3CDSENST00000490475ENST00000320996TTC28chr22

29025540

-PITPNBchr22

28269803

-
intron-3CDSENST00000490475ENST00000320996TTC28chr22

29025539

-PITPNBchr22

28269803

-
intron-3CDSENST00000490475ENST00000320996TTC28chr22

29025540

-PITPNBchr22

28256229

-
intron-3CDSENST00000490475ENST00000335272TTC28chr22

28385866

-PITPNBchr22

28269803

-
intron-3CDSENST00000490475ENST00000335272TTC28chr22

29025540

-PITPNBchr22

28269803

-
intron-3CDSENST00000490475ENST00000335272TTC28chr22

29025539

-PITPNBchr22

28269803

-
intron-3CDSENST00000490475ENST00000335272TTC28chr22

29025540

-PITPNBchr22

28256229

-
intron-3CDSENST00000490475ENST00000455418TTC28chr22

28385866

-PITPNBchr22

28269803

-
intron-3CDSENST00000490475ENST00000455418TTC28chr22

29025540

-PITPNBchr22

28269803

-
intron-3CDSENST00000490475ENST00000455418TTC28chr22

29025539

-PITPNBchr22

28269803

-
intron-3CDSENST00000490475ENST00000455418TTC28chr22

29025540

-PITPNBchr22

28256229

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000397906TTC28chr2229025539-ENST00000335272PITPNBchr2228269803-291652394882262
ENST00000397906TTC28chr2229025539-ENST00000320996PITPNBchr2228269803-282952394885263
ENST00000397906TTC28chr2229025539-ENST00000455418PITPNBchr2228269803-291352394882262
ENST00000397906TTC28chr2229025540-ENST00000335272PITPNBchr2228269803-291652394882262
ENST00000397906TTC28chr2229025540-ENST00000320996PITPNBchr2228269803-282952394885263
ENST00000397906TTC28chr2229025540-ENST00000455418PITPNBchr2228269803-291352394882262
ENST00000397906TTC28chr2229025540-ENST00000335272PITPNBchr2228256229-283852394804236
ENST00000397906TTC28chr2229025540-ENST00000320996PITPNBchr2228256229-275152394807237
ENST00000397906TTC28chr2229025540-ENST00000455418PITPNBchr2228256229-283552394804236

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000397906ENST00000335272TTC28chr2229025539-PITPNBchr2228269803-0.0007633030.9992367
ENST00000397906ENST00000320996TTC28chr2229025539-PITPNBchr2228269803-0.001114970.9988851
ENST00000397906ENST00000455418TTC28chr2229025539-PITPNBchr2228269803-0.0007427190.99925727
ENST00000397906ENST00000335272TTC28chr2229025540-PITPNBchr2228269803-0.0007633030.9992367
ENST00000397906ENST00000320996TTC28chr2229025540-PITPNBchr2228269803-0.001114970.9988851
ENST00000397906ENST00000455418TTC28chr2229025540-PITPNBchr2228269803-0.0007427190.99925727
ENST00000397906ENST00000335272TTC28chr2229025540-PITPNBchr2228256229-0.001798930.998201
ENST00000397906ENST00000320996TTC28chr2229025540-PITPNBchr2228256229-0.001955660.9980444
ENST00000397906ENST00000455418TTC28chr2229025540-PITPNBchr2228256229-0.001771190.99822885

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Fusion Genomic Features for TTC28-PITPNB


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TTC28-PITPNB


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:29025539/chr22:28269803)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-22358_911272482.0RepeatNote=TPR 1
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-22393_1251272482.0RepeatNote=TPR 2
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-22358_911272482.0RepeatNote=TPR 1
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-22393_1251272482.0RepeatNote=TPR 2
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-22358_911272482.0RepeatNote=TPR 1
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-22393_1251272482.0RepeatNote=TPR 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-2231948_20061272482.0Compositional biasNote=Ser-rich
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-2232201_23351272482.0Compositional biasNote=Ser-rich
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-2231948_20061272482.0Compositional biasNote=Ser-rich
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-2232201_23351272482.0Compositional biasNote=Ser-rich
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-2231948_20061272482.0Compositional biasNote=Ser-rich
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-2232201_23351272482.0Compositional biasNote=Ser-rich
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-2231037_10701272482.0RepeatNote=TPR 25
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-2231077_11101272482.0RepeatNote=TPR 26
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-2231117_11501272482.0RepeatNote=TPR 27
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-2231169_12021272482.0RepeatNote=TPR 28
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223126_1591272482.0RepeatNote=TPR 3
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223196_2291272482.0RepeatNote=TPR 4
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223234_2671272482.0RepeatNote=TPR 5
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223274_3071272482.0RepeatNote=TPR 6
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223314_3471272482.0RepeatNote=TPR 7
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223354_3871272482.0RepeatNote=TPR 8
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223394_4271272482.0RepeatNote=TPR 9
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223434_4671272482.0RepeatNote=TPR 10
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223474_5071272482.0RepeatNote=TPR 11
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223514_5471272482.0RepeatNote=TPR 12
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223554_5871272482.0RepeatNote=TPR 13
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223594_6271272482.0RepeatNote=TPR 14
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223634_6671272482.0RepeatNote=TPR 15
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223674_7071272482.0RepeatNote=TPR 16
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223714_7471272482.0RepeatNote=TPR 17
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223754_7871272482.0RepeatNote=TPR 18
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223794_8271272482.0RepeatNote=TPR 19
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223834_8671272482.0RepeatNote=TPR 20
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223877_9101272482.0RepeatNote=TPR 21
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223917_9501272482.0RepeatNote=TPR 22
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223957_9901272482.0RepeatNote=TPR 23
HgeneTTC28chr22:29025539chr22:28269803ENST00000397906-223997_10301272482.0RepeatNote=TPR 24
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-2231037_10701272482.0RepeatNote=TPR 25
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-2231077_11101272482.0RepeatNote=TPR 26
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-2231117_11501272482.0RepeatNote=TPR 27
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-2231169_12021272482.0RepeatNote=TPR 28
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223126_1591272482.0RepeatNote=TPR 3
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223196_2291272482.0RepeatNote=TPR 4
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223234_2671272482.0RepeatNote=TPR 5
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223274_3071272482.0RepeatNote=TPR 6
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223314_3471272482.0RepeatNote=TPR 7
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223354_3871272482.0RepeatNote=TPR 8
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223394_4271272482.0RepeatNote=TPR 9
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223434_4671272482.0RepeatNote=TPR 10
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223474_5071272482.0RepeatNote=TPR 11
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223514_5471272482.0RepeatNote=TPR 12
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223554_5871272482.0RepeatNote=TPR 13
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223594_6271272482.0RepeatNote=TPR 14
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223634_6671272482.0RepeatNote=TPR 15
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223674_7071272482.0RepeatNote=TPR 16
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223714_7471272482.0RepeatNote=TPR 17
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223754_7871272482.0RepeatNote=TPR 18
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223794_8271272482.0RepeatNote=TPR 19
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223834_8671272482.0RepeatNote=TPR 20
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223877_9101272482.0RepeatNote=TPR 21
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223917_9501272482.0RepeatNote=TPR 22
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223957_9901272482.0RepeatNote=TPR 23
HgeneTTC28chr22:29025540chr22:28256229ENST00000397906-223997_10301272482.0RepeatNote=TPR 24
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-2231037_10701272482.0RepeatNote=TPR 25
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-2231077_11101272482.0RepeatNote=TPR 26
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-2231117_11501272482.0RepeatNote=TPR 27
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-2231169_12021272482.0RepeatNote=TPR 28
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223126_1591272482.0RepeatNote=TPR 3
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223196_2291272482.0RepeatNote=TPR 4
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223234_2671272482.0RepeatNote=TPR 5
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223274_3071272482.0RepeatNote=TPR 6
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223314_3471272482.0RepeatNote=TPR 7
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223354_3871272482.0RepeatNote=TPR 8
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223394_4271272482.0RepeatNote=TPR 9
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223434_4671272482.0RepeatNote=TPR 10
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223474_5071272482.0RepeatNote=TPR 11
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223514_5471272482.0RepeatNote=TPR 12
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223554_5871272482.0RepeatNote=TPR 13
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223594_6271272482.0RepeatNote=TPR 14
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223634_6671272482.0RepeatNote=TPR 15
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223674_7071272482.0RepeatNote=TPR 16
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223714_7471272482.0RepeatNote=TPR 17
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223754_7871272482.0RepeatNote=TPR 18
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223794_8271272482.0RepeatNote=TPR 19
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223834_8671272482.0RepeatNote=TPR 20
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223877_9101272482.0RepeatNote=TPR 21
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223917_9501272482.0RepeatNote=TPR 22
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223957_9901272482.0RepeatNote=TPR 23
HgeneTTC28chr22:29025540chr22:28269803ENST00000397906-223997_10301272482.0RepeatNote=TPR 24


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Fusion Gene Sequence for TTC28-PITPNB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>94989_94989_1_TTC28-PITPNB_TTC28_chr22_29025539_ENST00000397906_PITPNB_chr22_28269803_ENST00000320996_length(transcript)=2829nt_BP=523nt
GGGGGCGCGCGCGCGGTTTGGGGGCAGTGAGGGGCGCCGCGGCGGCGCGCAGCACGGCGGGAACATGGCGCGCGGAACCGGCGCGCGCGC
CTAGCTGGCGGGACCGTTAGCTCGAGGCGGACGCGGCCCGGGCCCCGTGGGGATGGAGCAGTCGCCGCCGCCGGCGCCCGAGCCGACCCA
AGGGCCGACCCCCGCAAGGAGCCGAAGGCGGCGGGAGCCAGAGTCGCCGCCGGCGTCGGCGCCGATTCCTCTCTTTGGTGCTGACACTAT
TGGCCAGAGAAGTCCTGATGGACCGGTACTGAGCAAAGCTGAATTTGTTGAGAAAGTTCGTCAGAGTAATCAGGCCTGTCATGATGGAGA
TTTCCACACAGCTATTGTTCTGTATAATGAAGCCCTGGCTGTTGACCCTCAGAACTGCATCTTATACAGCAATAGATCTGCAGCCTACAT
GAAAATCCAGCAGTATGACAAGGCACTGGATGATGCAATCAAAGCTCGACTTCTCAATCCCAAGTGGCCAAAGGACTACAAAGCTGATGA
AGACCCAGCATTATTCCAGTCAGTCAAGACCAAGAGAGGCCCTTTGGGACCCAACTGGAAGAAGGAGCTGGCAAACAGCCCTGACTGTCC
CCAGATGTGTGCCTATAAGCTGGTGACCATCAAATTCAAGTGGTGGGGACTGCAAAGCAAAGTAGAAAACTTCATTCAAAAGCAAGAAAA
ACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGATGGAAGACATTAGGAGAATGGAAGA
CGAGACTCAGAAAGAACTAGAAACATTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGATGAGTGAAGAAGAATCTGACC
AGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAACCACGTGTGTATATATGTAT
GTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTATATATGTACATACAGACATA
CTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTTTCAATATATATACCTGGAAC
AGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATGTTTCATAAATGTCAAGCTGT
GGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAGTCCCATAAGCAGTAGACTCC
CACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATAACTATTTATTTCTGGATGGT
CATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTGCCCTGAGGGAAAAATCCTTT
TAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTAGCAAAAATGGAGATGACGGT
TTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAGTCTTAATAGGATTGTAGGCT
GTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACAGCTTGGAAACTATGCAAATG
GTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACACACACTTCAAGGAGGAGATA
GTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCCAAGAGACTGGTGGACATCTG
ACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGTCAGAAACGGCTGCCACTTTT
TTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCTGTCTGAATCCAGTTTTTCCT
CTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAACCTCCTGTCCCTCCTAAAACA
CGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGTTTTCCCACATGTCCTGCATC
CCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAATACCCTGTTATCCTCAGCAAC
AAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTGTAAGATAGGTTTTGTCAGAG
CATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAGCCCTCTCCTTTTAATGAACT
TAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGGATTTTAATGTTTTTCTAACA
ACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAATTACAGTAAAACAAAGTAAA

>94989_94989_1_TTC28-PITPNB_TTC28_chr22_29025539_ENST00000397906_PITPNB_chr22_28269803_ENST00000320996_length(amino acids)=263AA_BP=1
MAGPLARGGRGPGPVGMEQSPPPAPEPTQGPTPARSRRRREPESPPASAPIPLFGADTIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDF
HTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKDYKADEDPALFQSVKTKRGPLGPNWKKELANSPDCPQ

--------------------------------------------------------------
>94989_94989_2_TTC28-PITPNB_TTC28_chr22_29025539_ENST00000397906_PITPNB_chr22_28269803_ENST00000335272_length(transcript)=2916nt_BP=523nt
GGGGGCGCGCGCGCGGTTTGGGGGCAGTGAGGGGCGCCGCGGCGGCGCGCAGCACGGCGGGAACATGGCGCGCGGAACCGGCGCGCGCGC
CTAGCTGGCGGGACCGTTAGCTCGAGGCGGACGCGGCCCGGGCCCCGTGGGGATGGAGCAGTCGCCGCCGCCGGCGCCCGAGCCGACCCA
AGGGCCGACCCCCGCAAGGAGCCGAAGGCGGCGGGAGCCAGAGTCGCCGCCGGCGTCGGCGCCGATTCCTCTCTTTGGTGCTGACACTAT
TGGCCAGAGAAGTCCTGATGGACCGGTACTGAGCAAAGCTGAATTTGTTGAGAAAGTTCGTCAGAGTAATCAGGCCTGTCATGATGGAGA
TTTCCACACAGCTATTGTTCTGTATAATGAAGCCCTGGCTGTTGACCCTCAGAACTGCATCTTATACAGCAATAGATCTGCAGCCTACAT
GAAAATCCAGCAGTATGACAAGGCACTGGATGATGCAATCAAAGCTCGACTTCTCAATCCCAAGTGGCCAAAGGACTACAAAGCTGATGA
AGACCCAGCATTATTCCAGTCAGTCAAGACCAAGAGAGGCCCTTTGGGACCCAACTGGAAGAAGGAGCTGGCAAACAGCCCTGACTGTCC
CCAGATGTGTGCCTATAAGCTGGTGACCATCAAATTCAAGTGGTGGGGACTGCAAAGCAAAGTAGAAAACTTCATTCAAAAGCAAGAAAA
ACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGATGGAAGACATTAGGAGAATGGAAGA
CGAGACTCAGAAAGAACTAGAAACAATGCGTAAGAGGGGTTCCGTTCGAGGCACGTCGGCTGCTGATGTCTAGATGAGTCCCCTGTAGGG
TCAGAGACAATGTCAAACTGTTTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGATGAGTGAAGAAGAATCTGACCAGTA
TCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAACCACGTGTGTATATATGTATGTGT
GCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTATATATGTACATACAGACATACTGA
AGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTTTCAATATATATACCTGGAACAGAT
TTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATGTTTCATAAATGTCAAGCTGTGGAC
CAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAGTCCCATAAGCAGTAGACTCCCACA
GAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATAACTATTTATTTCTGGATGGTCATT
ATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTGCCCTGAGGGAAAAATCCTTTTAAA
AAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTAGCAAAAATGGAGATGACGGTTTCT
GATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAGTCTTAATAGGATTGTAGGCTGTGT
AGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACAGCTTGGAAACTATGCAAATGGTCT
AGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACACACACTTCAAGGAGGAGATAGTGA
CTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCCAAGAGACTGGTGGACATCTGACTG
TGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGTCAGAAACGGCTGCCACTTTTTTTA
ATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCTGTCTGAATCCAGTTTTTCCTCTGT
CAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAACCTCCTGTCCCTCCTAAAACACGCC
AACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGTTTTCCCACATGTCCTGCATCCCTC
CCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAATACCCTGTTATCCTCAGCAACAAAA
CCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTGTAAGATAGGTTTTGTCAGAGCATA
ATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAGCCCTCTCCTTTTAATGAACTTAAC
TCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGGATTTTAATGTTTTTCTAACAACTG
TGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAATTACAGTAAAACAAAGTAAATGAA

>94989_94989_2_TTC28-PITPNB_TTC28_chr22_29025539_ENST00000397906_PITPNB_chr22_28269803_ENST00000335272_length(amino acids)=262AA_BP=1
MAGPLARGGRGPGPVGMEQSPPPAPEPTQGPTPARSRRRREPESPPASAPIPLFGADTIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDF
HTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKDYKADEDPALFQSVKTKRGPLGPNWKKELANSPDCPQ

--------------------------------------------------------------
>94989_94989_3_TTC28-PITPNB_TTC28_chr22_29025539_ENST00000397906_PITPNB_chr22_28269803_ENST00000455418_length(transcript)=2913nt_BP=523nt
GGGGGCGCGCGCGCGGTTTGGGGGCAGTGAGGGGCGCCGCGGCGGCGCGCAGCACGGCGGGAACATGGCGCGCGGAACCGGCGCGCGCGC
CTAGCTGGCGGGACCGTTAGCTCGAGGCGGACGCGGCCCGGGCCCCGTGGGGATGGAGCAGTCGCCGCCGCCGGCGCCCGAGCCGACCCA
AGGGCCGACCCCCGCAAGGAGCCGAAGGCGGCGGGAGCCAGAGTCGCCGCCGGCGTCGGCGCCGATTCCTCTCTTTGGTGCTGACACTAT
TGGCCAGAGAAGTCCTGATGGACCGGTACTGAGCAAAGCTGAATTTGTTGAGAAAGTTCGTCAGAGTAATCAGGCCTGTCATGATGGAGA
TTTCCACACAGCTATTGTTCTGTATAATGAAGCCCTGGCTGTTGACCCTCAGAACTGCATCTTATACAGCAATAGATCTGCAGCCTACAT
GAAAATCCAGCAGTATGACAAGGCACTGGATGATGCAATCAAAGCTCGACTTCTCAATCCCAAGTGGCCAAAGGACTACAAAGCTGATGA
AGACCCAGCATTATTCCAGTCAGTCAAGACCAAGAGAGGCCCTTTGGGACCCAACTGGAAGAAGGAGCTGGCAAACAGCCCTGACTGTCC
CCAGATGTGTGCCTATAAGCTGGTGACCATCAAATTCAAGTGGTGGGGACTGCAAAGCAAAGTAGAAAACTTCATTCAAAAGCAAGAAAA
ACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGATGGAAGACATTAGGAGAATGGAAGA
CGAGACTCAGAAAGAACTAGAAACAATGCGTAAGAGGGGTTCCGTTCGAGGCACGTCGGCTGCTGATGTCTAGATGAGTCCCCTGTAGGG
TCAGAGACAATGTCAAACTGTTTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGATGAGTGAAGAAGAATCTGACCAGTA
TCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAACCACGTGTGTATATATGTATGTGT
GCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTATATATGTACATACAGACATACTGA
AGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTTTCAATATATATACCTGGAACAGAT
TTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATGTTTCATAAATGTCAAGCTGTGGAC
CAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAGTCCCATAAGCAGTAGACTCCCACA
GAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATAACTATTTATTTCTGGATGGTCATT
ATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTGCCCTGAGGGAAAAATCCTTTTAAA
AAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTAGCAAAAATGGAGATGACGGTTTCT
GATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAGTCTTAATAGGATTGTAGGCTGTGT
AGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACAGCTTGGAAACTATGCAAATGGTCT
AGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACACACACTTCAAGGAGGAGATAGTGA
CTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCCAAGAGACTGGTGGACATCTGACTG
TGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGTCAGAAACGGCTGCCACTTTTTTTA
ATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCTGTCTGAATCCAGTTTTTCCTCTGT
CAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAACCTCCTGTCCCTCCTAAAACACGCC
AACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGTTTTCCCACATGTCCTGCATCCCTC
CCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAATACCCTGTTATCCTCAGCAACAAAA
CCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTGTAAGATAGGTTTTGTCAGAGCATA
ATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAGCCCTCTCCTTTTAATGAACTTAAC
TCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGGATTTTAATGTTTTTCTAACAACTG
TGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAATTACAGTAAAACAAAGTAAATGAA

>94989_94989_3_TTC28-PITPNB_TTC28_chr22_29025539_ENST00000397906_PITPNB_chr22_28269803_ENST00000455418_length(amino acids)=262AA_BP=1
MAGPLARGGRGPGPVGMEQSPPPAPEPTQGPTPARSRRRREPESPPASAPIPLFGADTIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDF
HTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKDYKADEDPALFQSVKTKRGPLGPNWKKELANSPDCPQ

--------------------------------------------------------------
>94989_94989_4_TTC28-PITPNB_TTC28_chr22_29025540_ENST00000397906_PITPNB_chr22_28256229_ENST00000320996_length(transcript)=2751nt_BP=523nt
GGGGGCGCGCGCGCGGTTTGGGGGCAGTGAGGGGCGCCGCGGCGGCGCGCAGCACGGCGGGAACATGGCGCGCGGAACCGGCGCGCGCGC
CTAGCTGGCGGGACCGTTAGCTCGAGGCGGACGCGGCCCGGGCCCCGTGGGGATGGAGCAGTCGCCGCCGCCGGCGCCCGAGCCGACCCA
AGGGCCGACCCCCGCAAGGAGCCGAAGGCGGCGGGAGCCAGAGTCGCCGCCGGCGTCGGCGCCGATTCCTCTCTTTGGTGCTGACACTAT
TGGCCAGAGAAGTCCTGATGGACCGGTACTGAGCAAAGCTGAATTTGTTGAGAAAGTTCGTCAGAGTAATCAGGCCTGTCATGATGGAGA
TTTCCACACAGCTATTGTTCTGTATAATGAAGCCCTGGCTGTTGACCCTCAGAACTGCATCTTATACAGCAATAGATCTGCAGCCTACAT
GAAAATCCAGCAGTATGACAAGGCACTGGATGATGCAATCAAAGCTCGACTTCTCAATCCCAAGTGGCCAAAGAAGGAGCTGGCAAACAG
CCCTGACTGTCCCCAGATGTGTGCCTATAAGCTGGTGACCATCAAATTCAAGTGGTGGGGACTGCAAAGCAAAGTAGAAAACTTCATTCA
AAAGCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGATGGAAGACATTAG
GAGAATGGAAGACGAGACTCAGAAAGAACTAGAAACATTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGATGAGTGAAG
AAGAATCTGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAACCACGTGT
GTATATATGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTATATATGTA
CATACAGACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTTTCAATATA
TATACCTGGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATGTTTCATAA
ATGTCAAGCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAGTCCCATAA
GCAGTAGACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATAACTATTTA
TTTCTGGATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTGCCCTGAGG
GAAAAATCCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTAGCAAAAAT
GGAGATGACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAGTCTTAATA
GGATTGTAGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACAGCTTGGAA
ACTATGCAAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACACACACTTC
AAGGAGGAGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCCAAGAGACT
GGTGGACATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGTCAGAAACG
GCTGCCACTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCTGTCTGAAT
CCAGTTTTTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAACCTCCTGTC
CCTCCTAAAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGTTTTCCCAC
ATGTCCTGCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAATACCCTGTT
ATCCTCAGCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTGTAAGATAG
GTTTTGTCAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAGCCCTCTCC
TTTTAATGAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGGATTTTAAT
GTTTTTCTAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAATTACAGTA

>94989_94989_4_TTC28-PITPNB_TTC28_chr22_29025540_ENST00000397906_PITPNB_chr22_28256229_ENST00000320996_length(amino acids)=237AA_BP=143
MAGPLARGGRGPGPVGMEQSPPPAPEPTQGPTPARSRRRREPESPPASAPIPLFGADTIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDF
HTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKKELANSPDCPQMCAYKLVTIKFKWWGLQSKVENFIQK

--------------------------------------------------------------
>94989_94989_5_TTC28-PITPNB_TTC28_chr22_29025540_ENST00000397906_PITPNB_chr22_28256229_ENST00000335272_length(transcript)=2838nt_BP=523nt
GGGGGCGCGCGCGCGGTTTGGGGGCAGTGAGGGGCGCCGCGGCGGCGCGCAGCACGGCGGGAACATGGCGCGCGGAACCGGCGCGCGCGC
CTAGCTGGCGGGACCGTTAGCTCGAGGCGGACGCGGCCCGGGCCCCGTGGGGATGGAGCAGTCGCCGCCGCCGGCGCCCGAGCCGACCCA
AGGGCCGACCCCCGCAAGGAGCCGAAGGCGGCGGGAGCCAGAGTCGCCGCCGGCGTCGGCGCCGATTCCTCTCTTTGGTGCTGACACTAT
TGGCCAGAGAAGTCCTGATGGACCGGTACTGAGCAAAGCTGAATTTGTTGAGAAAGTTCGTCAGAGTAATCAGGCCTGTCATGATGGAGA
TTTCCACACAGCTATTGTTCTGTATAATGAAGCCCTGGCTGTTGACCCTCAGAACTGCATCTTATACAGCAATAGATCTGCAGCCTACAT
GAAAATCCAGCAGTATGACAAGGCACTGGATGATGCAATCAAAGCTCGACTTCTCAATCCCAAGTGGCCAAAGAAGGAGCTGGCAAACAG
CCCTGACTGTCCCCAGATGTGTGCCTATAAGCTGGTGACCATCAAATTCAAGTGGTGGGGACTGCAAAGCAAAGTAGAAAACTTCATTCA
AAAGCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGATGGAAGACATTAG
GAGAATGGAAGACGAGACTCAGAAAGAACTAGAAACAATGCGTAAGAGGGGTTCCGTTCGAGGCACGTCGGCTGCTGATGTCTAGATGAG
TCCCCTGTAGGGTCAGAGACAATGTCAAACTGTTTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGATGAGTGAAGAAGA
ATCTGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAACCACGTGTGTAT
ATATGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTATATATGTACATA
CAGACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTTTCAATATATATA
CCTGGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATGTTTCATAAATGT
CAAGCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAGTCCCATAAGCAG
TAGACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATAACTATTTATTTC
TGGATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTGCCCTGAGGGAAA
AATCCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTAGCAAAAATGGAG
ATGACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAGTCTTAATAGGAT
TGTAGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACAGCTTGGAAACTA
TGCAAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACACACACTTCAAGG
AGGAGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCCAAGAGACTGGTG
GACATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGTCAGAAACGGCTG
CCACTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCTGTCTGAATCCAG
TTTTTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAACCTCCTGTCCCTC
CTAAAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGTTTTCCCACATGT
CCTGCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAATACCCTGTTATCC
TCAGCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTGTAAGATAGGTTT
TGTCAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAGCCCTCTCCTTTT
AATGAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGGATTTTAATGTTT
TTCTAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAATTACAGTAAAAC

>94989_94989_5_TTC28-PITPNB_TTC28_chr22_29025540_ENST00000397906_PITPNB_chr22_28256229_ENST00000335272_length(amino acids)=236AA_BP=143
MAGPLARGGRGPGPVGMEQSPPPAPEPTQGPTPARSRRRREPESPPASAPIPLFGADTIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDF
HTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKKELANSPDCPQMCAYKLVTIKFKWWGLQSKVENFIQK

--------------------------------------------------------------
>94989_94989_6_TTC28-PITPNB_TTC28_chr22_29025540_ENST00000397906_PITPNB_chr22_28256229_ENST00000455418_length(transcript)=2835nt_BP=523nt
GGGGGCGCGCGCGCGGTTTGGGGGCAGTGAGGGGCGCCGCGGCGGCGCGCAGCACGGCGGGAACATGGCGCGCGGAACCGGCGCGCGCGC
CTAGCTGGCGGGACCGTTAGCTCGAGGCGGACGCGGCCCGGGCCCCGTGGGGATGGAGCAGTCGCCGCCGCCGGCGCCCGAGCCGACCCA
AGGGCCGACCCCCGCAAGGAGCCGAAGGCGGCGGGAGCCAGAGTCGCCGCCGGCGTCGGCGCCGATTCCTCTCTTTGGTGCTGACACTAT
TGGCCAGAGAAGTCCTGATGGACCGGTACTGAGCAAAGCTGAATTTGTTGAGAAAGTTCGTCAGAGTAATCAGGCCTGTCATGATGGAGA
TTTCCACACAGCTATTGTTCTGTATAATGAAGCCCTGGCTGTTGACCCTCAGAACTGCATCTTATACAGCAATAGATCTGCAGCCTACAT
GAAAATCCAGCAGTATGACAAGGCACTGGATGATGCAATCAAAGCTCGACTTCTCAATCCCAAGTGGCCAAAGAAGGAGCTGGCAAACAG
CCCTGACTGTCCCCAGATGTGTGCCTATAAGCTGGTGACCATCAAATTCAAGTGGTGGGGACTGCAAAGCAAAGTAGAAAACTTCATTCA
AAAGCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGATGGAAGACATTAG
GAGAATGGAAGACGAGACTCAGAAAGAACTAGAAACAATGCGTAAGAGGGGTTCCGTTCGAGGCACGTCGGCTGCTGATGTCTAGATGAG
TCCCCTGTAGGGTCAGAGACAATGTCAAACTGTTTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGATGAGTGAAGAAGA
ATCTGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAACCACGTGTGTAT
ATATGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTATATATGTACATA
CAGACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTTTCAATATATATA
CCTGGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATGTTTCATAAATGT
CAAGCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAGTCCCATAAGCAG
TAGACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATAACTATTTATTTC
TGGATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTGCCCTGAGGGAAA
AATCCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTAGCAAAAATGGAG
ATGACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAGTCTTAATAGGAT
TGTAGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACAGCTTGGAAACTA
TGCAAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACACACACTTCAAGG
AGGAGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCCAAGAGACTGGTG
GACATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGTCAGAAACGGCTG
CCACTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCTGTCTGAATCCAG
TTTTTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAACCTCCTGTCCCTC
CTAAAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGTTTTCCCACATGT
CCTGCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAATACCCTGTTATCC
TCAGCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTGTAAGATAGGTTT
TGTCAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAGCCCTCTCCTTTT
AATGAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGGATTTTAATGTTT
TTCTAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAATTACAGTAAAAC

>94989_94989_6_TTC28-PITPNB_TTC28_chr22_29025540_ENST00000397906_PITPNB_chr22_28256229_ENST00000455418_length(amino acids)=236AA_BP=143
MAGPLARGGRGPGPVGMEQSPPPAPEPTQGPTPARSRRRREPESPPASAPIPLFGADTIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDF
HTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKKELANSPDCPQMCAYKLVTIKFKWWGLQSKVENFIQK

--------------------------------------------------------------
>94989_94989_7_TTC28-PITPNB_TTC28_chr22_29025540_ENST00000397906_PITPNB_chr22_28269803_ENST00000320996_length(transcript)=2829nt_BP=523nt
GGGGGCGCGCGCGCGGTTTGGGGGCAGTGAGGGGCGCCGCGGCGGCGCGCAGCACGGCGGGAACATGGCGCGCGGAACCGGCGCGCGCGC
CTAGCTGGCGGGACCGTTAGCTCGAGGCGGACGCGGCCCGGGCCCCGTGGGGATGGAGCAGTCGCCGCCGCCGGCGCCCGAGCCGACCCA
AGGGCCGACCCCCGCAAGGAGCCGAAGGCGGCGGGAGCCAGAGTCGCCGCCGGCGTCGGCGCCGATTCCTCTCTTTGGTGCTGACACTAT
TGGCCAGAGAAGTCCTGATGGACCGGTACTGAGCAAAGCTGAATTTGTTGAGAAAGTTCGTCAGAGTAATCAGGCCTGTCATGATGGAGA
TTTCCACACAGCTATTGTTCTGTATAATGAAGCCCTGGCTGTTGACCCTCAGAACTGCATCTTATACAGCAATAGATCTGCAGCCTACAT
GAAAATCCAGCAGTATGACAAGGCACTGGATGATGCAATCAAAGCTCGACTTCTCAATCCCAAGTGGCCAAAGGACTACAAAGCTGATGA
AGACCCAGCATTATTCCAGTCAGTCAAGACCAAGAGAGGCCCTTTGGGACCCAACTGGAAGAAGGAGCTGGCAAACAGCCCTGACTGTCC
CCAGATGTGTGCCTATAAGCTGGTGACCATCAAATTCAAGTGGTGGGGACTGCAAAGCAAAGTAGAAAACTTCATTCAAAAGCAAGAAAA
ACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGATGGAAGACATTAGGAGAATGGAAGA
CGAGACTCAGAAAGAACTAGAAACATTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGATGAGTGAAGAAGAATCTGACC
AGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAACCACGTGTGTATATATGTAT
GTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTATATATGTACATACAGACATA
CTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTTTCAATATATATACCTGGAAC
AGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATGTTTCATAAATGTCAAGCTGT
GGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAGTCCCATAAGCAGTAGACTCC
CACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATAACTATTTATTTCTGGATGGT
CATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTGCCCTGAGGGAAAAATCCTTT
TAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTAGCAAAAATGGAGATGACGGT
TTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAGTCTTAATAGGATTGTAGGCT
GTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACAGCTTGGAAACTATGCAAATG
GTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACACACACTTCAAGGAGGAGATA
GTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCCAAGAGACTGGTGGACATCTG
ACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGTCAGAAACGGCTGCCACTTTT
TTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCTGTCTGAATCCAGTTTTTCCT
CTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAACCTCCTGTCCCTCCTAAAACA
CGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGTTTTCCCACATGTCCTGCATC
CCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAATACCCTGTTATCCTCAGCAAC
AAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTGTAAGATAGGTTTTGTCAGAG
CATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAGCCCTCTCCTTTTAATGAACT
TAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGGATTTTAATGTTTTTCTAACA
ACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAATTACAGTAAAACAAAGTAAA

>94989_94989_7_TTC28-PITPNB_TTC28_chr22_29025540_ENST00000397906_PITPNB_chr22_28269803_ENST00000320996_length(amino acids)=263AA_BP=1
MAGPLARGGRGPGPVGMEQSPPPAPEPTQGPTPARSRRRREPESPPASAPIPLFGADTIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDF
HTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKDYKADEDPALFQSVKTKRGPLGPNWKKELANSPDCPQ

--------------------------------------------------------------
>94989_94989_8_TTC28-PITPNB_TTC28_chr22_29025540_ENST00000397906_PITPNB_chr22_28269803_ENST00000335272_length(transcript)=2916nt_BP=523nt
GGGGGCGCGCGCGCGGTTTGGGGGCAGTGAGGGGCGCCGCGGCGGCGCGCAGCACGGCGGGAACATGGCGCGCGGAACCGGCGCGCGCGC
CTAGCTGGCGGGACCGTTAGCTCGAGGCGGACGCGGCCCGGGCCCCGTGGGGATGGAGCAGTCGCCGCCGCCGGCGCCCGAGCCGACCCA
AGGGCCGACCCCCGCAAGGAGCCGAAGGCGGCGGGAGCCAGAGTCGCCGCCGGCGTCGGCGCCGATTCCTCTCTTTGGTGCTGACACTAT
TGGCCAGAGAAGTCCTGATGGACCGGTACTGAGCAAAGCTGAATTTGTTGAGAAAGTTCGTCAGAGTAATCAGGCCTGTCATGATGGAGA
TTTCCACACAGCTATTGTTCTGTATAATGAAGCCCTGGCTGTTGACCCTCAGAACTGCATCTTATACAGCAATAGATCTGCAGCCTACAT
GAAAATCCAGCAGTATGACAAGGCACTGGATGATGCAATCAAAGCTCGACTTCTCAATCCCAAGTGGCCAAAGGACTACAAAGCTGATGA
AGACCCAGCATTATTCCAGTCAGTCAAGACCAAGAGAGGCCCTTTGGGACCCAACTGGAAGAAGGAGCTGGCAAACAGCCCTGACTGTCC
CCAGATGTGTGCCTATAAGCTGGTGACCATCAAATTCAAGTGGTGGGGACTGCAAAGCAAAGTAGAAAACTTCATTCAAAAGCAAGAAAA
ACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGATGGAAGACATTAGGAGAATGGAAGA
CGAGACTCAGAAAGAACTAGAAACAATGCGTAAGAGGGGTTCCGTTCGAGGCACGTCGGCTGCTGATGTCTAGATGAGTCCCCTGTAGGG
TCAGAGACAATGTCAAACTGTTTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGATGAGTGAAGAAGAATCTGACCAGTA
TCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAACCACGTGTGTATATATGTATGTGT
GCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTATATATGTACATACAGACATACTGA
AGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTTTCAATATATATACCTGGAACAGAT
TTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATGTTTCATAAATGTCAAGCTGTGGAC
CAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAGTCCCATAAGCAGTAGACTCCCACA
GAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATAACTATTTATTTCTGGATGGTCATT
ATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTGCCCTGAGGGAAAAATCCTTTTAAA
AAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTAGCAAAAATGGAGATGACGGTTTCT
GATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAGTCTTAATAGGATTGTAGGCTGTGT
AGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACAGCTTGGAAACTATGCAAATGGTCT
AGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACACACACTTCAAGGAGGAGATAGTGA
CTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCCAAGAGACTGGTGGACATCTGACTG
TGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGTCAGAAACGGCTGCCACTTTTTTTA
ATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCTGTCTGAATCCAGTTTTTCCTCTGT
CAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAACCTCCTGTCCCTCCTAAAACACGCC
AACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGTTTTCCCACATGTCCTGCATCCCTC
CCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAATACCCTGTTATCCTCAGCAACAAAA
CCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTGTAAGATAGGTTTTGTCAGAGCATA
ATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAGCCCTCTCCTTTTAATGAACTTAAC
TCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGGATTTTAATGTTTTTCTAACAACTG
TGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAATTACAGTAAAACAAAGTAAATGAA

>94989_94989_8_TTC28-PITPNB_TTC28_chr22_29025540_ENST00000397906_PITPNB_chr22_28269803_ENST00000335272_length(amino acids)=262AA_BP=1
MAGPLARGGRGPGPVGMEQSPPPAPEPTQGPTPARSRRRREPESPPASAPIPLFGADTIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDF
HTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKDYKADEDPALFQSVKTKRGPLGPNWKKELANSPDCPQ

--------------------------------------------------------------
>94989_94989_9_TTC28-PITPNB_TTC28_chr22_29025540_ENST00000397906_PITPNB_chr22_28269803_ENST00000455418_length(transcript)=2913nt_BP=523nt
GGGGGCGCGCGCGCGGTTTGGGGGCAGTGAGGGGCGCCGCGGCGGCGCGCAGCACGGCGGGAACATGGCGCGCGGAACCGGCGCGCGCGC
CTAGCTGGCGGGACCGTTAGCTCGAGGCGGACGCGGCCCGGGCCCCGTGGGGATGGAGCAGTCGCCGCCGCCGGCGCCCGAGCCGACCCA
AGGGCCGACCCCCGCAAGGAGCCGAAGGCGGCGGGAGCCAGAGTCGCCGCCGGCGTCGGCGCCGATTCCTCTCTTTGGTGCTGACACTAT
TGGCCAGAGAAGTCCTGATGGACCGGTACTGAGCAAAGCTGAATTTGTTGAGAAAGTTCGTCAGAGTAATCAGGCCTGTCATGATGGAGA
TTTCCACACAGCTATTGTTCTGTATAATGAAGCCCTGGCTGTTGACCCTCAGAACTGCATCTTATACAGCAATAGATCTGCAGCCTACAT
GAAAATCCAGCAGTATGACAAGGCACTGGATGATGCAATCAAAGCTCGACTTCTCAATCCCAAGTGGCCAAAGGACTACAAAGCTGATGA
AGACCCAGCATTATTCCAGTCAGTCAAGACCAAGAGAGGCCCTTTGGGACCCAACTGGAAGAAGGAGCTGGCAAACAGCCCTGACTGTCC
CCAGATGTGTGCCTATAAGCTGGTGACCATCAAATTCAAGTGGTGGGGACTGCAAAGCAAAGTAGAAAACTTCATTCAAAAGCAAGAAAA
ACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACGATGGAAGACATTAGGAGAATGGAAGA
CGAGACTCAGAAAGAACTAGAAACAATGCGTAAGAGGGGTTCCGTTCGAGGCACGTCGGCTGCTGATGTCTAGATGAGTCCCCTGTAGGG
TCAGAGACAATGTCAAACTGTTTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCCAGTGATGAGTGAAGAAGAATCTGACCAGTA
TCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGTTCTCAACCACGTGTGTATATATGTATGTGT
GCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACTTGTGTATATATGTACATACAGACATACTGA
AGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAAATATTTTCAATATATATACCTGGAACAGAT
TTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCTGGTATGTTTCATAAATGTCAAGCTGTGGAC
CAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTTTTTTAGTCCCATAAGCAGTAGACTCCCACA
GAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTATTTATAACTATTTATTTCTGGATGGTCATT
ATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACTTGTTTGCCCTGAGGGAAAAATCCTTTTAAA
AAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCAAACCTAGCAAAAATGGAGATGACGGTTTCT
GATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGAAATTAGTCTTAATAGGATTGTAGGCTGTGT
AGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTAACTACAGCTTGGAAACTATGCAAATGGTCT
AGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTGGGAACACACACTTCAAGGAGGAGATAGTGA
CTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCCAAGAGACTGGTGGACATCTGACTG
TGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGTGCTGGTCAGAAACGGCTGCCACTTTTTTTA
ATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCTTTCTCTGTCTGAATCCAGTTTTTCCTCTGT
CAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTTTGTAACCTCCTGTCCCTCCTAAAACACGCC
AACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGTTTTCCCACATGTCCTGCATCCCTC
CCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCATTGCAATACCCTGTTATCCTCAGCAACAAAA
CCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCACTGTTGTAAGATAGGTTTTGTCAGAGCATA
ATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGAGTCTAGCCCTCTCCTTTTAATGAACTTAAC
TCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGCGCATGGATTTTAATGTTTTTCTAACAACTG
TGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTGTGTAAATTACAGTAAAACAAAGTAAATGAA

>94989_94989_9_TTC28-PITPNB_TTC28_chr22_29025540_ENST00000397906_PITPNB_chr22_28269803_ENST00000455418_length(amino acids)=262AA_BP=1
MAGPLARGGRGPGPVGMEQSPPPAPEPTQGPTPARSRRRREPESPPASAPIPLFGADTIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDF
HTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKDYKADEDPALFQSVKTKRGPLGPNWKKELANSPDCPQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TTC28-PITPNB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TTC28-PITPNB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TTC28-PITPNB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource