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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TUBD1-CDK12 (FusionGDB2 ID:95378)

Fusion Gene Summary for TUBD1-CDK12

check button Fusion gene summary
Fusion gene informationFusion gene name: TUBD1-CDK12
Fusion gene ID: 95378
HgeneTgene
Gene symbol

TUBD1

CDK12

Gene ID

51174

51755

Gene nametubulin delta 1cyclin dependent kinase 12
SynonymsTUBDCRK7|CRKR|CRKRS
Cytomap

17q23.1

17q12

Type of geneprotein-codingprotein-coding
Descriptiontubulin delta chaindelta-tubulincyclin-dependent kinase 12CDC2-related protein kinase 7Cdc2-related kinase, arginine/serine-richcell division cycle 2-related protein kinase 7cell division protein kinase 12
Modification date2020031320200313
UniProtAcc.

Q9NYV4

Ensembl transtripts involved in fusion geneENST00000325752, ENST00000340993, 
ENST00000346141, ENST00000376094, 
ENST00000394239, ENST00000539018, 
ENST00000592426, ENST00000591611, 
ENST00000559545, ENST00000430627, 
ENST00000447079, 
Fusion gene scores* DoF score16 X 16 X 8=204836 X 30 X 14=15120
# samples 2255
** MAII scorelog2(22/2048*10)=-3.21864028647534
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(55/15120*10)=-4.78088271069641
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TUBD1 [Title/Abstract] AND CDK12 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTUBD1(57943970)-CDK12(37667782), # samples:3
Anticipated loss of major functional domain due to fusion event.TUBD1-CDK12 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
TUBD1-CDK12 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
TUBD1-CDK12 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
TUBD1-CDK12 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
TUBD1-CDK12 seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCDK12

GO:0046777

protein autophosphorylation

11683387


check buttonFusion gene breakpoints across TUBD1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CDK12 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A1-A0SN-01ATUBD1chr17

57943969

-CDK12chr17

37667781

+
ChimerDB4BRCATCGA-A1-A0SN-01ATUBD1chr17

57943970

-CDK12chr17

37667782

+
ChimerDB4BRCATCGA-A1-A0SN-01ATUBD1chr17

57951899

-CDK12chr17

37667781

+
ChimerDB4BRCATCGA-A1-A0SN-01ATUBD1chr17

57951900

-CDK12chr17

37667782

+
ChimerDB4BRCATCGA-A1-A0SN-01ATUBD1chr17

57955464

-CDK12chr17

37667782

+


Top

Fusion Gene ORF analysis for TUBD1-CDK12

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000325752ENST00000559545TUBD1chr17

57943969

-CDK12chr17

37667781

+
5CDS-intronENST00000325752ENST00000559545TUBD1chr17

57943970

-CDK12chr17

37667782

+
5CDS-intronENST00000325752ENST00000559545TUBD1chr17

57951899

-CDK12chr17

37667781

+
5CDS-intronENST00000325752ENST00000559545TUBD1chr17

57951900

-CDK12chr17

37667782

+
5CDS-intronENST00000325752ENST00000559545TUBD1chr17

57955464

-CDK12chr17

37667782

+
5CDS-intronENST00000340993ENST00000559545TUBD1chr17

57943969

-CDK12chr17

37667781

+
5CDS-intronENST00000340993ENST00000559545TUBD1chr17

57943970

-CDK12chr17

37667782

+
5CDS-intronENST00000340993ENST00000559545TUBD1chr17

57955464

-CDK12chr17

37667782

+
5CDS-intronENST00000346141ENST00000559545TUBD1chr17

57943969

-CDK12chr17

37667781

+
5CDS-intronENST00000346141ENST00000559545TUBD1chr17

57943970

-CDK12chr17

37667782

+
5CDS-intronENST00000376094ENST00000559545TUBD1chr17

57955464

-CDK12chr17

37667782

+
5CDS-intronENST00000394239ENST00000559545TUBD1chr17

57951899

-CDK12chr17

37667781

+
5CDS-intronENST00000394239ENST00000559545TUBD1chr17

57951900

-CDK12chr17

37667782

+
5CDS-intronENST00000394239ENST00000559545TUBD1chr17

57955464

-CDK12chr17

37667782

+
5CDS-intronENST00000539018ENST00000559545TUBD1chr17

57943969

-CDK12chr17

37667781

+
5CDS-intronENST00000539018ENST00000559545TUBD1chr17

57943970

-CDK12chr17

37667782

+
5CDS-intronENST00000539018ENST00000559545TUBD1chr17

57951899

-CDK12chr17

37667781

+
5CDS-intronENST00000539018ENST00000559545TUBD1chr17

57951900

-CDK12chr17

37667782

+
5CDS-intronENST00000539018ENST00000559545TUBD1chr17

57955464

-CDK12chr17

37667782

+
5CDS-intronENST00000592426ENST00000559545TUBD1chr17

57943969

-CDK12chr17

37667781

+
5CDS-intronENST00000592426ENST00000559545TUBD1chr17

57943970

-CDK12chr17

37667782

+
5CDS-intronENST00000592426ENST00000559545TUBD1chr17

57951899

-CDK12chr17

37667781

+
5CDS-intronENST00000592426ENST00000559545TUBD1chr17

57951900

-CDK12chr17

37667782

+
5CDS-intronENST00000592426ENST00000559545TUBD1chr17

57955464

-CDK12chr17

37667782

+
Frame-shiftENST00000376094ENST00000430627TUBD1chr17

57955464

-CDK12chr17

37667782

+
Frame-shiftENST00000376094ENST00000447079TUBD1chr17

57955464

-CDK12chr17

37667782

+
Frame-shiftENST00000539018ENST00000430627TUBD1chr17

57943969

-CDK12chr17

37667781

+
Frame-shiftENST00000539018ENST00000430627TUBD1chr17

57943970

-CDK12chr17

37667782

+
Frame-shiftENST00000539018ENST00000430627TUBD1chr17

57951899

-CDK12chr17

37667781

+
Frame-shiftENST00000539018ENST00000430627TUBD1chr17

57951900

-CDK12chr17

37667782

+
Frame-shiftENST00000539018ENST00000430627TUBD1chr17

57955464

-CDK12chr17

37667782

+
Frame-shiftENST00000539018ENST00000447079TUBD1chr17

57943969

-CDK12chr17

37667781

+
Frame-shiftENST00000539018ENST00000447079TUBD1chr17

57943970

-CDK12chr17

37667782

+
Frame-shiftENST00000539018ENST00000447079TUBD1chr17

57951899

-CDK12chr17

37667781

+
Frame-shiftENST00000539018ENST00000447079TUBD1chr17

57951900

-CDK12chr17

37667782

+
Frame-shiftENST00000539018ENST00000447079TUBD1chr17

57955464

-CDK12chr17

37667782

+
Frame-shiftENST00000592426ENST00000430627TUBD1chr17

57943969

-CDK12chr17

37667781

+
Frame-shiftENST00000592426ENST00000430627TUBD1chr17

57943970

-CDK12chr17

37667782

+
Frame-shiftENST00000592426ENST00000430627TUBD1chr17

57951899

-CDK12chr17

37667781

+
Frame-shiftENST00000592426ENST00000430627TUBD1chr17

57951900

-CDK12chr17

37667782

+
Frame-shiftENST00000592426ENST00000430627TUBD1chr17

57955464

-CDK12chr17

37667782

+
Frame-shiftENST00000592426ENST00000447079TUBD1chr17

57943969

-CDK12chr17

37667781

+
Frame-shiftENST00000592426ENST00000447079TUBD1chr17

57943970

-CDK12chr17

37667782

+
Frame-shiftENST00000592426ENST00000447079TUBD1chr17

57951899

-CDK12chr17

37667781

+
Frame-shiftENST00000592426ENST00000447079TUBD1chr17

57951900

-CDK12chr17

37667782

+
Frame-shiftENST00000592426ENST00000447079TUBD1chr17

57955464

-CDK12chr17

37667782

+
In-frameENST00000325752ENST00000430627TUBD1chr17

57943969

-CDK12chr17

37667781

+
In-frameENST00000325752ENST00000430627TUBD1chr17

57943970

-CDK12chr17

37667782

+
In-frameENST00000325752ENST00000430627TUBD1chr17

57951899

-CDK12chr17

37667781

+
In-frameENST00000325752ENST00000430627TUBD1chr17

57951900

-CDK12chr17

37667782

+
In-frameENST00000325752ENST00000430627TUBD1chr17

57955464

-CDK12chr17

37667782

+
In-frameENST00000325752ENST00000447079TUBD1chr17

57943969

-CDK12chr17

37667781

+
In-frameENST00000325752ENST00000447079TUBD1chr17

57943970

-CDK12chr17

37667782

+
In-frameENST00000325752ENST00000447079TUBD1chr17

57951899

-CDK12chr17

37667781

+
In-frameENST00000325752ENST00000447079TUBD1chr17

57951900

-CDK12chr17

37667782

+
In-frameENST00000325752ENST00000447079TUBD1chr17

57955464

-CDK12chr17

37667782

+
In-frameENST00000340993ENST00000430627TUBD1chr17

57943969

-CDK12chr17

37667781

+
In-frameENST00000340993ENST00000430627TUBD1chr17

57943970

-CDK12chr17

37667782

+
In-frameENST00000340993ENST00000430627TUBD1chr17

57955464

-CDK12chr17

37667782

+
In-frameENST00000340993ENST00000447079TUBD1chr17

57943969

-CDK12chr17

37667781

+
In-frameENST00000340993ENST00000447079TUBD1chr17

57943970

-CDK12chr17

37667782

+
In-frameENST00000340993ENST00000447079TUBD1chr17

57955464

-CDK12chr17

37667782

+
In-frameENST00000346141ENST00000430627TUBD1chr17

57943969

-CDK12chr17

37667781

+
In-frameENST00000346141ENST00000430627TUBD1chr17

57943970

-CDK12chr17

37667782

+
In-frameENST00000346141ENST00000447079TUBD1chr17

57943969

-CDK12chr17

37667781

+
In-frameENST00000346141ENST00000447079TUBD1chr17

57943970

-CDK12chr17

37667782

+
In-frameENST00000394239ENST00000430627TUBD1chr17

57951899

-CDK12chr17

37667781

+
In-frameENST00000394239ENST00000430627TUBD1chr17

57951900

-CDK12chr17

37667782

+
In-frameENST00000394239ENST00000430627TUBD1chr17

57955464

-CDK12chr17

37667782

+
In-frameENST00000394239ENST00000447079TUBD1chr17

57951899

-CDK12chr17

37667781

+
In-frameENST00000394239ENST00000447079TUBD1chr17

57951900

-CDK12chr17

37667782

+
In-frameENST00000394239ENST00000447079TUBD1chr17

57955464

-CDK12chr17

37667782

+
intron-3CDSENST00000340993ENST00000430627TUBD1chr17

57951899

-CDK12chr17

37667781

+
intron-3CDSENST00000340993ENST00000430627TUBD1chr17

57951900

-CDK12chr17

37667782

+
intron-3CDSENST00000340993ENST00000447079TUBD1chr17

57951899

-CDK12chr17

37667781

+
intron-3CDSENST00000340993ENST00000447079TUBD1chr17

57951900

-CDK12chr17

37667782

+
intron-3CDSENST00000346141ENST00000430627TUBD1chr17

57951899

-CDK12chr17

37667781

+
intron-3CDSENST00000346141ENST00000430627TUBD1chr17

57951900

-CDK12chr17

37667782

+
intron-3CDSENST00000346141ENST00000430627TUBD1chr17

57955464

-CDK12chr17

37667782

+
intron-3CDSENST00000346141ENST00000447079TUBD1chr17

57951899

-CDK12chr17

37667781

+
intron-3CDSENST00000346141ENST00000447079TUBD1chr17

57951900

-CDK12chr17

37667782

+
intron-3CDSENST00000346141ENST00000447079TUBD1chr17

57955464

-CDK12chr17

37667782

+
intron-3CDSENST00000376094ENST00000430627TUBD1chr17

57943969

-CDK12chr17

37667781

+
intron-3CDSENST00000376094ENST00000430627TUBD1chr17

57943970

-CDK12chr17

37667782

+
intron-3CDSENST00000376094ENST00000430627TUBD1chr17

57951899

-CDK12chr17

37667781

+
intron-3CDSENST00000376094ENST00000430627TUBD1chr17

57951900

-CDK12chr17

37667782

+
intron-3CDSENST00000376094ENST00000447079TUBD1chr17

57943969

-CDK12chr17

37667781

+
intron-3CDSENST00000376094ENST00000447079TUBD1chr17

57943970

-CDK12chr17

37667782

+
intron-3CDSENST00000376094ENST00000447079TUBD1chr17

57951899

-CDK12chr17

37667781

+
intron-3CDSENST00000376094ENST00000447079TUBD1chr17

57951900

-CDK12chr17

37667782

+
intron-3CDSENST00000394239ENST00000430627TUBD1chr17

57943969

-CDK12chr17

37667781

+
intron-3CDSENST00000394239ENST00000430627TUBD1chr17

57943970

-CDK12chr17

37667782

+
intron-3CDSENST00000394239ENST00000447079TUBD1chr17

57943969

-CDK12chr17

37667781

+
intron-3CDSENST00000394239ENST00000447079TUBD1chr17

57943970

-CDK12chr17

37667782

+
intron-3CDSENST00000591611ENST00000430627TUBD1chr17

57943969

-CDK12chr17

37667781

+
intron-3CDSENST00000591611ENST00000430627TUBD1chr17

57943970

-CDK12chr17

37667782

+
intron-3CDSENST00000591611ENST00000430627TUBD1chr17

57951899

-CDK12chr17

37667781

+
intron-3CDSENST00000591611ENST00000430627TUBD1chr17

57951900

-CDK12chr17

37667782

+
intron-3CDSENST00000591611ENST00000430627TUBD1chr17

57955464

-CDK12chr17

37667782

+
intron-3CDSENST00000591611ENST00000447079TUBD1chr17

57943969

-CDK12chr17

37667781

+
intron-3CDSENST00000591611ENST00000447079TUBD1chr17

57943970

-CDK12chr17

37667782

+
intron-3CDSENST00000591611ENST00000447079TUBD1chr17

57951899

-CDK12chr17

37667781

+
intron-3CDSENST00000591611ENST00000447079TUBD1chr17

57951900

-CDK12chr17

37667782

+
intron-3CDSENST00000591611ENST00000447079TUBD1chr17

57955464

-CDK12chr17

37667782

+
intron-intronENST00000340993ENST00000559545TUBD1chr17

57951899

-CDK12chr17

37667781

+
intron-intronENST00000340993ENST00000559545TUBD1chr17

57951900

-CDK12chr17

37667782

+
intron-intronENST00000346141ENST00000559545TUBD1chr17

57951899

-CDK12chr17

37667781

+
intron-intronENST00000346141ENST00000559545TUBD1chr17

57951900

-CDK12chr17

37667782

+
intron-intronENST00000346141ENST00000559545TUBD1chr17

57955464

-CDK12chr17

37667782

+
intron-intronENST00000376094ENST00000559545TUBD1chr17

57943969

-CDK12chr17

37667781

+
intron-intronENST00000376094ENST00000559545TUBD1chr17

57943970

-CDK12chr17

37667782

+
intron-intronENST00000376094ENST00000559545TUBD1chr17

57951899

-CDK12chr17

37667781

+
intron-intronENST00000376094ENST00000559545TUBD1chr17

57951900

-CDK12chr17

37667782

+
intron-intronENST00000394239ENST00000559545TUBD1chr17

57943969

-CDK12chr17

37667781

+
intron-intronENST00000394239ENST00000559545TUBD1chr17

57943970

-CDK12chr17

37667782

+
intron-intronENST00000591611ENST00000559545TUBD1chr17

57943969

-CDK12chr17

37667781

+
intron-intronENST00000591611ENST00000559545TUBD1chr17

57943970

-CDK12chr17

37667782

+
intron-intronENST00000591611ENST00000559545TUBD1chr17

57951899

-CDK12chr17

37667781

+
intron-intronENST00000591611ENST00000559545TUBD1chr17

57951900

-CDK12chr17

37667782

+
intron-intronENST00000591611ENST00000559545TUBD1chr17

57955464

-CDK12chr17

37667782

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000346141TUBD1chr1757943970-ENST00000430627CDK12chr1737667782+33123713992150583
ENST00000346141TUBD1chr1757943970-ENST00000447079CDK12chr1737667782+60083713992177592
ENST00000325752TUBD1chr1757943970-ENST00000430627CDK12chr1737667782+4294135313813132583
ENST00000325752TUBD1chr1757943970-ENST00000447079CDK12chr1737667782+6990135313813159592
ENST00000340993TUBD1chr1757943970-ENST00000430627CDK12chr1737667782+4114117312012952583
ENST00000340993TUBD1chr1757943970-ENST00000447079CDK12chr1737667782+6810117312012979592
ENST00000325752TUBD1chr1757951900-ENST00000430627CDK12chr1737667782+4153121212402991583
ENST00000325752TUBD1chr1757951900-ENST00000447079CDK12chr1737667782+6849121212403018592
ENST00000394239TUBD1chr1757951900-ENST00000430627CDK12chr1737667782+4076113511632914583
ENST00000394239TUBD1chr1757951900-ENST00000447079CDK12chr1737667782+6772113511632941592
ENST00000325752TUBD1chr1757955464-ENST00000430627CDK12chr1737667782+3988104710752826583
ENST00000325752TUBD1chr1757955464-ENST00000447079CDK12chr1737667782+6684104710752853592
ENST00000340993TUBD1chr1757955464-ENST00000430627CDK12chr1737667782+3973103210602811583
ENST00000340993TUBD1chr1757955464-ENST00000447079CDK12chr1737667782+6669103210602838592
ENST00000394239TUBD1chr1757955464-ENST00000430627CDK12chr1737667782+39119709982749583
ENST00000394239TUBD1chr1757955464-ENST00000447079CDK12chr1737667782+66079709982776592
ENST00000346141TUBD1chr1757943969-ENST00000430627CDK12chr1737667781+33123713992150583
ENST00000346141TUBD1chr1757943969-ENST00000447079CDK12chr1737667781+60083713992177592
ENST00000325752TUBD1chr1757943969-ENST00000430627CDK12chr1737667781+4294135313813132583
ENST00000325752TUBD1chr1757943969-ENST00000447079CDK12chr1737667781+6990135313813159592
ENST00000340993TUBD1chr1757943969-ENST00000430627CDK12chr1737667781+4114117312012952583
ENST00000340993TUBD1chr1757943969-ENST00000447079CDK12chr1737667781+6810117312012979592
ENST00000325752TUBD1chr1757951899-ENST00000430627CDK12chr1737667781+4153121212402991583
ENST00000325752TUBD1chr1757951899-ENST00000447079CDK12chr1737667781+6849121212403018592
ENST00000394239TUBD1chr1757951899-ENST00000430627CDK12chr1737667781+4076113511632914583
ENST00000394239TUBD1chr1757951899-ENST00000447079CDK12chr1737667781+6772113511632941592

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000346141ENST00000430627TUBD1chr1757943970-CDK12chr1737667782+0.0056276920.99437225
ENST00000346141ENST00000447079TUBD1chr1757943970-CDK12chr1737667782+0.0008826930.9991173
ENST00000325752ENST00000430627TUBD1chr1757943970-CDK12chr1737667782+0.0036724760.99632746
ENST00000325752ENST00000447079TUBD1chr1757943970-CDK12chr1737667782+0.0010977530.9989022
ENST00000340993ENST00000430627TUBD1chr1757943970-CDK12chr1737667782+0.0037415950.9962584
ENST00000340993ENST00000447079TUBD1chr1757943970-CDK12chr1737667782+0.0010393890.9989606
ENST00000325752ENST00000430627TUBD1chr1757951900-CDK12chr1737667782+0.0043324360.9956676
ENST00000325752ENST00000447079TUBD1chr1757951900-CDK12chr1737667782+0.0011458760.99885416
ENST00000394239ENST00000430627TUBD1chr1757951900-CDK12chr1737667782+0.0044570520.99554294
ENST00000394239ENST00000447079TUBD1chr1757951900-CDK12chr1737667782+0.0011331920.9988668
ENST00000325752ENST00000430627TUBD1chr1757955464-CDK12chr1737667782+0.0044911680.9955088
ENST00000325752ENST00000447079TUBD1chr1757955464-CDK12chr1737667782+0.0010910550.998909
ENST00000340993ENST00000430627TUBD1chr1757955464-CDK12chr1737667782+0.0044339280.99556607
ENST00000340993ENST00000447079TUBD1chr1757955464-CDK12chr1737667782+0.0010861550.9989139
ENST00000394239ENST00000430627TUBD1chr1757955464-CDK12chr1737667782+0.00464560.9953544
ENST00000394239ENST00000447079TUBD1chr1757955464-CDK12chr1737667782+0.001079010.99892104
ENST00000346141ENST00000430627TUBD1chr1757943969-CDK12chr1737667781+0.0056276920.99437225
ENST00000346141ENST00000447079TUBD1chr1757943969-CDK12chr1737667781+0.0008826930.9991173
ENST00000325752ENST00000430627TUBD1chr1757943969-CDK12chr1737667781+0.0036724760.99632746
ENST00000325752ENST00000447079TUBD1chr1757943969-CDK12chr1737667781+0.0010977530.9989022
ENST00000340993ENST00000430627TUBD1chr1757943969-CDK12chr1737667781+0.0037415950.9962584
ENST00000340993ENST00000447079TUBD1chr1757943969-CDK12chr1737667781+0.0010393890.9989606
ENST00000325752ENST00000430627TUBD1chr1757951899-CDK12chr1737667781+0.0043324360.9956676
ENST00000325752ENST00000447079TUBD1chr1757951899-CDK12chr1737667781+0.0011458760.99885416
ENST00000394239ENST00000430627TUBD1chr1757951899-CDK12chr1737667781+0.0044570520.99554294
ENST00000394239ENST00000447079TUBD1chr1757951899-CDK12chr1737667781+0.0011331920.9988668

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Fusion Genomic Features for TUBD1-CDK12


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TUBD1chr1757955463-CDK12chr1737667781+0.0014733940.9985266
TUBD1chr1757951899-CDK12chr1737667781+9.41E-050.9999058
TUBD1chr1757943969-CDK12chr1737667781+3.06E-081
TUBD1chr1757955463-CDK12chr1737667781+0.0014733940.9985266
TUBD1chr1757951899-CDK12chr1737667781+9.41E-050.9999058
TUBD1chr1757943969-CDK12chr1737667781+3.06E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for TUBD1-CDK12


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:57943970/chr17:37667782)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CDK12

Q9NYV4

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors. {ECO:0000269|PubMed:11683387, ECO:0000269|PubMed:19651820, ECO:0000269|PubMed:20952539, ECO:0000269|PubMed:22012619, ECO:0000269|PubMed:24662513}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTUBD1chr17:57943969chr17:37667781ENST00000325752-79143_149358454.0Nucleotide bindingGTP
HgeneTUBD1chr17:57943969chr17:37667781ENST00000340993-68143_149303399.0Nucleotide bindingGTP
HgeneTUBD1chr17:57943969chr17:37667781ENST00000592426-68143_149358454.0Nucleotide bindingGTP
HgeneTUBD1chr17:57943970chr17:37667782ENST00000325752-79143_149358454.0Nucleotide bindingGTP
HgeneTUBD1chr17:57943970chr17:37667782ENST00000340993-68143_149303399.0Nucleotide bindingGTP
HgeneTUBD1chr17:57943970chr17:37667782ENST00000592426-68143_149358454.0Nucleotide bindingGTP
HgeneTUBD1chr17:57951899chr17:37667781ENST00000325752-69143_149311454.0Nucleotide bindingGTP
HgeneTUBD1chr17:57951899chr17:37667781ENST00000394239-68143_149311397.0Nucleotide bindingGTP
HgeneTUBD1chr17:57951899chr17:37667781ENST00000592426-58143_149311454.0Nucleotide bindingGTP
HgeneTUBD1chr17:57951900chr17:37667782ENST00000325752-69143_149311454.0Nucleotide bindingGTP
HgeneTUBD1chr17:57951900chr17:37667782ENST00000394239-68143_149311397.0Nucleotide bindingGTP
HgeneTUBD1chr17:57951900chr17:37667782ENST00000592426-58143_149311454.0Nucleotide bindingGTP
HgeneTUBD1chr17:57955464chr17:37667782ENST00000325752-59143_149256454.0Nucleotide bindingGTP
HgeneTUBD1chr17:57955464chr17:37667782ENST00000340993-58143_149256399.0Nucleotide bindingGTP
HgeneTUBD1chr17:57955464chr17:37667782ENST00000376094-46143_149256352.0Nucleotide bindingGTP
HgeneTUBD1chr17:57955464chr17:37667782ENST00000394239-58143_149256397.0Nucleotide bindingGTP
HgeneTUBD1chr17:57955464chr17:37667782ENST00000592426-48143_149256454.0Nucleotide bindingGTP
TgeneCDK12chr17:57943969chr17:37667781ENST000004306276141266_12808881482.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57943969chr17:37667781ENST000004470796141266_12808881491.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57943970chr17:37667782ENST000004306276141266_12808881482.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57943970chr17:37667782ENST000004470796141266_12808881491.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57951899chr17:37667781ENST000004306276141266_12808881482.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57951899chr17:37667781ENST000004470796141266_12808881491.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57951900chr17:37667782ENST000004306276141266_12808881482.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57951900chr17:37667782ENST000004470796141266_12808881491.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57955464chr17:37667782ENST000004306276141266_12808881482.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57955464chr17:37667782ENST000004470796141266_12808881491.0Compositional biasNote=Poly-Pro

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTUBD1chr17:57943969chr17:37667781ENST00000346141-35143_149104200.0Nucleotide bindingGTP
HgeneTUBD1chr17:57943969chr17:37667781ENST00000376094-16143_1490352.0Nucleotide bindingGTP
HgeneTUBD1chr17:57943969chr17:37667781ENST00000394239-18143_1490397.0Nucleotide bindingGTP
HgeneTUBD1chr17:57943969chr17:37667781ENST00000539018-46143_149142238.0Nucleotide bindingGTP
HgeneTUBD1chr17:57943970chr17:37667782ENST00000346141-35143_149104200.0Nucleotide bindingGTP
HgeneTUBD1chr17:57943970chr17:37667782ENST00000376094-16143_1490352.0Nucleotide bindingGTP
HgeneTUBD1chr17:57943970chr17:37667782ENST00000394239-18143_1490397.0Nucleotide bindingGTP
HgeneTUBD1chr17:57943970chr17:37667782ENST00000539018-46143_149142238.0Nucleotide bindingGTP
HgeneTUBD1chr17:57951899chr17:37667781ENST00000340993-18143_1490399.0Nucleotide bindingGTP
HgeneTUBD1chr17:57951899chr17:37667781ENST00000346141-15143_1490200.0Nucleotide bindingGTP
HgeneTUBD1chr17:57951899chr17:37667781ENST00000376094-16143_1490352.0Nucleotide bindingGTP
HgeneTUBD1chr17:57951899chr17:37667781ENST00000539018-36143_14995238.0Nucleotide bindingGTP
HgeneTUBD1chr17:57951900chr17:37667782ENST00000340993-18143_1490399.0Nucleotide bindingGTP
HgeneTUBD1chr17:57951900chr17:37667782ENST00000346141-15143_1490200.0Nucleotide bindingGTP
HgeneTUBD1chr17:57951900chr17:37667782ENST00000376094-16143_1490352.0Nucleotide bindingGTP
HgeneTUBD1chr17:57951900chr17:37667782ENST00000539018-36143_14995238.0Nucleotide bindingGTP
HgeneTUBD1chr17:57955464chr17:37667782ENST00000346141-15143_1490200.0Nucleotide bindingGTP
HgeneTUBD1chr17:57955464chr17:37667782ENST00000539018-26143_14940238.0Nucleotide bindingGTP
TgeneCDK12chr17:57943969chr17:37667781ENST00000430627614407_4138881482.0Compositional biasNote=Poly-Ala
TgeneCDK12chr17:57943969chr17:37667781ENST00000430627614535_5408881482.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57943969chr17:37667781ENST00000447079614407_4138881491.0Compositional biasNote=Poly-Ala
TgeneCDK12chr17:57943969chr17:37667781ENST00000447079614535_5408881491.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57943970chr17:37667782ENST00000430627614407_4138881482.0Compositional biasNote=Poly-Ala
TgeneCDK12chr17:57943970chr17:37667782ENST00000430627614535_5408881482.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57943970chr17:37667782ENST00000447079614407_4138881491.0Compositional biasNote=Poly-Ala
TgeneCDK12chr17:57943970chr17:37667782ENST00000447079614535_5408881491.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57951899chr17:37667781ENST00000430627614407_4138881482.0Compositional biasNote=Poly-Ala
TgeneCDK12chr17:57951899chr17:37667781ENST00000430627614535_5408881482.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57951899chr17:37667781ENST00000447079614407_4138881491.0Compositional biasNote=Poly-Ala
TgeneCDK12chr17:57951899chr17:37667781ENST00000447079614535_5408881491.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57951900chr17:37667782ENST00000430627614407_4138881482.0Compositional biasNote=Poly-Ala
TgeneCDK12chr17:57951900chr17:37667782ENST00000430627614535_5408881482.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57951900chr17:37667782ENST00000447079614407_4138881491.0Compositional biasNote=Poly-Ala
TgeneCDK12chr17:57951900chr17:37667782ENST00000447079614535_5408881491.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57955464chr17:37667782ENST00000430627614407_4138881482.0Compositional biasNote=Poly-Ala
TgeneCDK12chr17:57955464chr17:37667782ENST00000430627614535_5408881482.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57955464chr17:37667782ENST00000447079614407_4138881491.0Compositional biasNote=Poly-Ala
TgeneCDK12chr17:57955464chr17:37667782ENST00000447079614535_5408881491.0Compositional biasNote=Poly-Pro
TgeneCDK12chr17:57943969chr17:37667781ENST00000430627614727_10208881482.0DomainProtein kinase
TgeneCDK12chr17:57943969chr17:37667781ENST00000447079614727_10208881491.0DomainProtein kinase
TgeneCDK12chr17:57943970chr17:37667782ENST00000430627614727_10208881482.0DomainProtein kinase
TgeneCDK12chr17:57943970chr17:37667782ENST00000447079614727_10208881491.0DomainProtein kinase
TgeneCDK12chr17:57951899chr17:37667781ENST00000430627614727_10208881482.0DomainProtein kinase
TgeneCDK12chr17:57951899chr17:37667781ENST00000447079614727_10208881491.0DomainProtein kinase
TgeneCDK12chr17:57951900chr17:37667782ENST00000430627614727_10208881482.0DomainProtein kinase
TgeneCDK12chr17:57951900chr17:37667782ENST00000447079614727_10208881491.0DomainProtein kinase
TgeneCDK12chr17:57955464chr17:37667782ENST00000430627614727_10208881482.0DomainProtein kinase
TgeneCDK12chr17:57955464chr17:37667782ENST00000447079614727_10208881491.0DomainProtein kinase
TgeneCDK12chr17:57943969chr17:37667781ENST00000430627614733_7418881482.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57943969chr17:37667781ENST00000430627614814_8198881482.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57943969chr17:37667781ENST00000447079614733_7418881491.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57943969chr17:37667781ENST00000447079614814_8198881491.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57943970chr17:37667782ENST00000430627614733_7418881482.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57943970chr17:37667782ENST00000430627614814_8198881482.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57943970chr17:37667782ENST00000447079614733_7418881491.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57943970chr17:37667782ENST00000447079614814_8198881491.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57951899chr17:37667781ENST00000430627614733_7418881482.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57951899chr17:37667781ENST00000430627614814_8198881482.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57951899chr17:37667781ENST00000447079614733_7418881491.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57951899chr17:37667781ENST00000447079614814_8198881491.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57951900chr17:37667782ENST00000430627614733_7418881482.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57951900chr17:37667782ENST00000430627614814_8198881482.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57951900chr17:37667782ENST00000447079614733_7418881491.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57951900chr17:37667782ENST00000447079614814_8198881491.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57955464chr17:37667782ENST00000430627614733_7418881482.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57955464chr17:37667782ENST00000430627614814_8198881482.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57955464chr17:37667782ENST00000447079614733_7418881491.0Nucleotide bindingNote=ATP
TgeneCDK12chr17:57955464chr17:37667782ENST00000447079614814_8198881491.0Nucleotide bindingNote=ATP


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Fusion Gene Sequence for TUBD1-CDK12


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>95378_95378_1_TUBD1-CDK12_TUBD1_chr17_57943969_ENST00000325752_CDK12_chr17_37667781_ENST00000430627_length(transcript)=4294nt_BP=1353nt
AGCTGGAGCGTTCGGTGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATA
GGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGC
ATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGT
GGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCAC
ACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAG
TTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAAT
ATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAAT
CTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGAT
CAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTG
GTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATG
CCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTG
TGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGAGACTTAATGGAGCATTTAGTTCCCCATCCTG
AATTCAAGATGCTGAGTGTTCGTAACATTCCTCACATGTCTGAGAATTCATTGGCATACACCACATTTACTTGGGCTGGCCTCCTCAAGC
ATTTGAGACAGATGCTCATTTCTAATGCAAAGATGGAAGAAGGTATTGATAGGCATGTATGGCCTCCTTTATCAGGACTTCCTCCTCTTA
GTAAAATGTCTCTCAACAAGGACCTGCATTTTAACACTTCCATTGCTAACTTGGTCATTCTTCGTGGGAAAGATGTGCAAAGTGCAGATG
TGGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGA
TGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGAT
CAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATA
TCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCG
GTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGA
TTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAA
AGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGC
TGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGA
CCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAG
TGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGAT
CCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGAT
GAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCC
ACAGGAGGAGGCAGCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTC
CAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCC
ACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGG
GTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTC
AGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAG
GGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATT
GCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGC
TTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGT
CCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATT
TGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCT
GGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAA
TGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATT
TTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATA
GTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCC
ACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAA
AGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACT
TTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT
GTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCT
TTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACC
ATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAG

>95378_95378_1_TUBD1-CDK12_TUBD1_chr17_57943969_ENST00000325752_CDK12_chr17_37667781_ENST00000430627_length(amino acids)=583AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPP
EPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERN
SGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGT

--------------------------------------------------------------
>95378_95378_2_TUBD1-CDK12_TUBD1_chr17_57943969_ENST00000325752_CDK12_chr17_37667781_ENST00000447079_length(transcript)=6990nt_BP=1353nt
AGCTGGAGCGTTCGGTGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATA
GGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGC
ATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGT
GGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCAC
ACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAG
TTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAAT
ATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAAT
CTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGAT
CAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTG
GTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATG
CCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTG
TGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGAGACTTAATGGAGCATTTAGTTCCCCATCCTG
AATTCAAGATGCTGAGTGTTCGTAACATTCCTCACATGTCTGAGAATTCATTGGCATACACCACATTTACTTGGGCTGGCCTCCTCAAGC
ATTTGAGACAGATGCTCATTTCTAATGCAAAGATGGAAGAAGGTATTGATAGGCATGTATGGCCTCCTTTATCAGGACTTCCTCCTCTTA
GTAAAATGTCTCTCAACAAGGACCTGCATTTTAACACTTCCATTGCTAACTTGGTCATTCTTCGTGGGAAAGATGTGCAAAGTGCAGATG
TGGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGA
TGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGAT
CAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATA
TCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCG
GTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGA
TTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAA
AGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGC
TGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGA
CCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAG
TGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGAT
CCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGAT
GAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCC
ACAGGAGGAGGCAGCAGCATGTCCTCCTCACATTCTTCCACCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCC
ACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCC
TGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTA
TGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCA
GACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCC
AGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAA
TTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCA
CTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGT
TCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATT
TGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAA
ATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATG
GAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTG
AGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTT
TTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTG
ATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTT
TTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACG
TGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTC
TCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTG
AGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCA
ATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGG
TTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATATTGTTTACACATATATTTTTATGTCAAAAAAAAAACAAAA
ACCTTTCAAACAGAGCATTGTGATATTGTCAAAGAGAAAAACAAATCCTGAAGATACATGGAAATGTAACCTAGTTTAGGGTGGGTATTT
TTCTGAAGATACATCAATACCTGACCTTTTTTAAAAAAATAATTTTAAAACAGCATACTGTGAGGAAGAACAGTATTGACATACCCACAT
CCCAGCATGTGTACCCTGCCAGTTCTTTTAGGGATTTTTCCTCCAAAGAGATTTGGATTTGGTTTTGGTAAAAGGGGTTAAATTGTGCTT
CCAGGCAAGAACTTTGCCTTATCATAAACAGGAAATGAAAAAGGGAAGGGCTGTCAGGATGGGATAATTTGGGAGGCTTCTCATTCTGGC
TTCTATTTCTATGTGAGTACCAGCATATAGAGTGTTTTAAAAACAGATACATGTCATATAATTTATCTGCACAGACTTAGACCTTCAGGA
AACATAGGTTAAGCCCCCTTTTACAAAGAAAAAGTAAACATACTTCAGCATCTTGGAGGGTAGTTTTCAAAACTCAAGTTTCATGTTTCA
ATGCCAAGTTCTTATTTTAAAAAATAAAATCTACTTATAAGAGAAAGGTGCATTACTTAAAAAAAAAAAACTTTAAAGAAATGAAAGAAG
AACCCTCTTCAGATACTTACTTGAAGACTGTTTTCCCCTGTTAATGAGATATAGCTAGATATCGGTGTGTGTATTTCTTTATTATTCTCT
GGTTTTTGATCTGGCCTTGCCTCCAGGGCCAAACACTGATTTAGAAAGAGAGCCTTCTAGCTATTTTGGCATTGATGGCTTTTTATACCA
GTGTGTCCAGTTAGATTTACTAGGCTTACTGACATGCTATTGGTAAATCGCATTAAAGTTCATCTGAACCTTCTGTCTGTTGACTTCTTA
GTCCTCAGACATGGGCCTTTGTGTTTTAGAATATTTGAATTTGAGTTATTGGGCCCCACTCCCTGTTTTTTATTAAAGAACGTGAGCCTG
GGATACTTTCAGAAGTATCTGTTCAATGAAAAAAAGTTGGTTTCCCATCAAATATGAATAAAATTCTCTATATATTTCATTGTATTTTGG
TTATCAGCAGTCATCAATAATGTTTTTCCCTCCCCTCTCCCACCTCTTATTTTTAATTATGCCAAATATCCTAAATAATATACTTAAGCC
TCCATTCCCTCATCCCTACTAGGGAAGGGGGTGAGTGTATGTGTGAGTGTATGTGTATGTATGATCCCATCTCACCCCCACCCCCATTTT
GGGAGTCTTTTAAAATGAAAACAAAGTTTGGTAGTTTTGACTATTTCTAAAAGCAGAGGAGAAAAAAAAACTTATTTAAATATCCTGGAA
TCTGTATGGAGGAAGAAAAGGTATTTGTTAATTTTTCAGTTACGTTATCTATAAACATGATGGAAGTAAAGGTTTGGCAGAATTTCACCT
TGACTATTTGAAAATTACAGACCCAATTAATTCCATTCAAAAGTGGTTTTCGTTTTGTTTTAATTATTGTACAATGAGAGATATTGTCTA
TTAAATACATTATTTTGAACAGATGAGAAATCTGATTCTGTTCATGAGTGGGAGGCAAAACTGGTTTGACCGTGATCATTTTTGTGGTTT
TGAAAACAAATATACTTGACCCAGTTTCCTTAGTTTTTTCTTCAACTGTCCATAGGAACGATAAGTATTTGAAAGCAACATCAAATCTAT
ACGTTTAAAGCAGGGCAGTTAGCACAAATTTGCAAGTAGAACTTCTATTAGCTTATGCCATAGACATCACCCAACCACTTGTATGTGTGT
GTGTATATATAATATGCATATATAGTTACCGTGCTAAAATGGTTACCAGCAGGTTTTGAGAGAGAATGCTGCATCAGAAAAGTGTCAGTT
GCCACCTCATTCTCCCTGATTTAGGTTCCTGACACTGATTCCTTTCTCTCTCGTTTTTGACCCCCATTGGGTGTATCTTGTCTATGTACA
GATATTTTGTAATATATTAAATTTTTTTCTTTCAGTTTATAAAAATGGAAAGTGGAGATTGGAAAATTAAATATTTCCTGTTACTATACC
ACTTTTGCTCCATTGCATTTACTTCTTAATCTGTACCCCCTGAGCATATCTAATCATGTATAAAGGACGTTTTTCCTCCACTTTATCTTA
GGGGTTCTCTGTCTCAGAATCATTATAGACTCATTAACTCCCCCTCCCAGCAAAAGGTTATCAGGATTTGAAGAGGTGCTTGAAAACGCT
AGACTAGGAACTAGAGAATAAATGAGTTGGGAAAAACCATGAAATGTGATTTTTTTAAAGTAGAAAAGTTATACAAATAATGGTACCAAA
CCATCAAAAGAGTTGAGCTTCATGTACCCTGACTCCTCCTGACAGGAGAGGTAAGTGGGTTTGAGCTCAACTGTCATCAAGGGAAGTTGG
TAAGAGGCTGTTTAGACCCAAAGGATAGTCTTAAACCAGACTTCACCACCCACCCTACCTCAGTTCCCATGTTATTACATGCAGAGTCAG
CATGGGGATTAGTGTACCTACCTTTGCTGAGATTTCCCGATGCGTTGCCAATCCAGAAAGTGAATCAAAAAGTTGTTTAAAAGTTAAAAT

>95378_95378_2_TUBD1-CDK12_TUBD1_chr17_57943969_ENST00000325752_CDK12_chr17_37667781_ENST00000447079_length(amino acids)=592AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPH
ILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGF
SAIDTDERNSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQ

--------------------------------------------------------------
>95378_95378_3_TUBD1-CDK12_TUBD1_chr17_57943969_ENST00000340993_CDK12_chr17_37667781_ENST00000430627_length(transcript)=4114nt_BP=1173nt
TGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATAGGAAAAAATATATAC
ACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGCATGGTGAGTAGGTTG
GTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGTGGCTCAGCATGTCAA
TTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCACACAGTTCCCAGGGAC
TCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAGTTCCAATTGCCCGGG
CTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAATATGGTCAACATGCAT
GCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAATCTATAATGAACATAA
TCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGATCAGGATTAGGAGCTT
TCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTGGTGAGGTTATTGTTC
AAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATGCCATCCATAAGATCT
GTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTGTGTTCCAGCCTACTT
ATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGTATTGATAGGCATGTATGGCCTCCTTTATCAGGACTTCCTCCTCTTA
GTAAAATGTCTCTCAACAAGGACCTGCATTTTAACACTTCCATTGCTAACTTGGTCATTCTTCGTGGGAAAGATGTGCAAAGTGCAGATG
TGGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGA
TGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGAT
CAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATA
TCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCG
GTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGA
TTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAA
AGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGC
TGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGA
CCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAG
TGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGAT
CCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGAT
GAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCC
ACAGGAGGAGGCAGCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTC
CAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCC
ACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGG
GTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTC
AGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAG
GGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATT
GCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGC
TTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGT
CCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATT
TGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCT
GGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAA
TGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATT
TTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATA
GTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCC
ACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAA
AGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACT
TTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT
GTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCT
TTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACC
ATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAG

>95378_95378_3_TUBD1-CDK12_TUBD1_chr17_57943969_ENST00000340993_CDK12_chr17_37667781_ENST00000430627_length(amino acids)=583AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPP
EPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERN
SGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGT

--------------------------------------------------------------
>95378_95378_4_TUBD1-CDK12_TUBD1_chr17_57943969_ENST00000340993_CDK12_chr17_37667781_ENST00000447079_length(transcript)=6810nt_BP=1173nt
TGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATAGGAAAAAATATATAC
ACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGCATGGTGAGTAGGTTG
GTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGTGGCTCAGCATGTCAA
TTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCACACAGTTCCCAGGGAC
TCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAGTTCCAATTGCCCGGG
CTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAATATGGTCAACATGCAT
GCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAATCTATAATGAACATAA
TCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGATCAGGATTAGGAGCTT
TCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTGGTGAGGTTATTGTTC
AAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATGCCATCCATAAGATCT
GTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTGTGTTCCAGCCTACTT
ATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGTATTGATAGGCATGTATGGCCTCCTTTATCAGGACTTCCTCCTCTTA
GTAAAATGTCTCTCAACAAGGACCTGCATTTTAACACTTCCATTGCTAACTTGGTCATTCTTCGTGGGAAAGATGTGCAAAGTGCAGATG
TGGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGA
TGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGAT
CAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATA
TCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCG
GTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGA
TTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAA
AGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGC
TGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGA
CCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAG
TGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGAT
CCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGAT
GAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCC
ACAGGAGGAGGCAGCAGCATGTCCTCCTCACATTCTTCCACCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCC
ACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCC
TGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTA
TGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCA
GACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCC
AGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAA
TTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCA
CTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGT
TCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATT
TGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAA
ATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATG
GAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTG
AGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTT
TTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTG
ATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTT
TTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACG
TGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTC
TCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTG
AGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCA
ATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGG
TTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATATTGTTTACACATATATTTTTATGTCAAAAAAAAAACAAAA
ACCTTTCAAACAGAGCATTGTGATATTGTCAAAGAGAAAAACAAATCCTGAAGATACATGGAAATGTAACCTAGTTTAGGGTGGGTATTT
TTCTGAAGATACATCAATACCTGACCTTTTTTAAAAAAATAATTTTAAAACAGCATACTGTGAGGAAGAACAGTATTGACATACCCACAT
CCCAGCATGTGTACCCTGCCAGTTCTTTTAGGGATTTTTCCTCCAAAGAGATTTGGATTTGGTTTTGGTAAAAGGGGTTAAATTGTGCTT
CCAGGCAAGAACTTTGCCTTATCATAAACAGGAAATGAAAAAGGGAAGGGCTGTCAGGATGGGATAATTTGGGAGGCTTCTCATTCTGGC
TTCTATTTCTATGTGAGTACCAGCATATAGAGTGTTTTAAAAACAGATACATGTCATATAATTTATCTGCACAGACTTAGACCTTCAGGA
AACATAGGTTAAGCCCCCTTTTACAAAGAAAAAGTAAACATACTTCAGCATCTTGGAGGGTAGTTTTCAAAACTCAAGTTTCATGTTTCA
ATGCCAAGTTCTTATTTTAAAAAATAAAATCTACTTATAAGAGAAAGGTGCATTACTTAAAAAAAAAAAACTTTAAAGAAATGAAAGAAG
AACCCTCTTCAGATACTTACTTGAAGACTGTTTTCCCCTGTTAATGAGATATAGCTAGATATCGGTGTGTGTATTTCTTTATTATTCTCT
GGTTTTTGATCTGGCCTTGCCTCCAGGGCCAAACACTGATTTAGAAAGAGAGCCTTCTAGCTATTTTGGCATTGATGGCTTTTTATACCA
GTGTGTCCAGTTAGATTTACTAGGCTTACTGACATGCTATTGGTAAATCGCATTAAAGTTCATCTGAACCTTCTGTCTGTTGACTTCTTA
GTCCTCAGACATGGGCCTTTGTGTTTTAGAATATTTGAATTTGAGTTATTGGGCCCCACTCCCTGTTTTTTATTAAAGAACGTGAGCCTG
GGATACTTTCAGAAGTATCTGTTCAATGAAAAAAAGTTGGTTTCCCATCAAATATGAATAAAATTCTCTATATATTTCATTGTATTTTGG
TTATCAGCAGTCATCAATAATGTTTTTCCCTCCCCTCTCCCACCTCTTATTTTTAATTATGCCAAATATCCTAAATAATATACTTAAGCC
TCCATTCCCTCATCCCTACTAGGGAAGGGGGTGAGTGTATGTGTGAGTGTATGTGTATGTATGATCCCATCTCACCCCCACCCCCATTTT
GGGAGTCTTTTAAAATGAAAACAAAGTTTGGTAGTTTTGACTATTTCTAAAAGCAGAGGAGAAAAAAAAACTTATTTAAATATCCTGGAA
TCTGTATGGAGGAAGAAAAGGTATTTGTTAATTTTTCAGTTACGTTATCTATAAACATGATGGAAGTAAAGGTTTGGCAGAATTTCACCT
TGACTATTTGAAAATTACAGACCCAATTAATTCCATTCAAAAGTGGTTTTCGTTTTGTTTTAATTATTGTACAATGAGAGATATTGTCTA
TTAAATACATTATTTTGAACAGATGAGAAATCTGATTCTGTTCATGAGTGGGAGGCAAAACTGGTTTGACCGTGATCATTTTTGTGGTTT
TGAAAACAAATATACTTGACCCAGTTTCCTTAGTTTTTTCTTCAACTGTCCATAGGAACGATAAGTATTTGAAAGCAACATCAAATCTAT
ACGTTTAAAGCAGGGCAGTTAGCACAAATTTGCAAGTAGAACTTCTATTAGCTTATGCCATAGACATCACCCAACCACTTGTATGTGTGT
GTGTATATATAATATGCATATATAGTTACCGTGCTAAAATGGTTACCAGCAGGTTTTGAGAGAGAATGCTGCATCAGAAAAGTGTCAGTT
GCCACCTCATTCTCCCTGATTTAGGTTCCTGACACTGATTCCTTTCTCTCTCGTTTTTGACCCCCATTGGGTGTATCTTGTCTATGTACA
GATATTTTGTAATATATTAAATTTTTTTCTTTCAGTTTATAAAAATGGAAAGTGGAGATTGGAAAATTAAATATTTCCTGTTACTATACC
ACTTTTGCTCCATTGCATTTACTTCTTAATCTGTACCCCCTGAGCATATCTAATCATGTATAAAGGACGTTTTTCCTCCACTTTATCTTA
GGGGTTCTCTGTCTCAGAATCATTATAGACTCATTAACTCCCCCTCCCAGCAAAAGGTTATCAGGATTTGAAGAGGTGCTTGAAAACGCT
AGACTAGGAACTAGAGAATAAATGAGTTGGGAAAAACCATGAAATGTGATTTTTTTAAAGTAGAAAAGTTATACAAATAATGGTACCAAA
CCATCAAAAGAGTTGAGCTTCATGTACCCTGACTCCTCCTGACAGGAGAGGTAAGTGGGTTTGAGCTCAACTGTCATCAAGGGAAGTTGG
TAAGAGGCTGTTTAGACCCAAAGGATAGTCTTAAACCAGACTTCACCACCCACCCTACCTCAGTTCCCATGTTATTACATGCAGAGTCAG
CATGGGGATTAGTGTACCTACCTTTGCTGAGATTTCCCGATGCGTTGCCAATCCAGAAAGTGAATCAAAAAGTTGTTTAAAAGTTAAAAT

>95378_95378_4_TUBD1-CDK12_TUBD1_chr17_57943969_ENST00000340993_CDK12_chr17_37667781_ENST00000447079_length(amino acids)=592AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPH
ILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGF
SAIDTDERNSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQ

--------------------------------------------------------------
>95378_95378_5_TUBD1-CDK12_TUBD1_chr17_57943969_ENST00000346141_CDK12_chr17_37667781_ENST00000430627_length(transcript)=3312nt_BP=371nt
CGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGTGGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTG
TGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCACACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGC
ATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAGGTATTGATAGGCATGTATGGCCTCCTTTATCAGGACTTCC
TCCTCTTAGTAAAATGTCTCTCAACAAGGACCTGCATTTTAACACTTCCATTGCTAACTTGGTCATTCTTCGTGGGAAAGATGTGCAAAG
TGCAGATGTGGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCA
GCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTA
GAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAG
AAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCT
AGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCAC
TGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACT
TCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAG
TCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGC
CAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAA
TCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCC
CCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGT
CAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCC
ACAATGCCACAGGAGGAGGCAGCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGC
GATCTTTCCAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGC
CACCTGCCACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCT
GAAACAGGGTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGG
ACCTTCTCAGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGT
TTTGCCAGGGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAG
ACCAAATTGCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAG
TCTTCTGCTTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGAC
TTCAGTGTCCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCA
TCTGCATTTGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAG
TTCCCCCTGGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGA
AAAGTAAATGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCT
CTTTGATTTTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAA
AGAGAATAGTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTT
TCCTCTCCACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTC
ATCCTTAAAGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTA
GGTAGACTTTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT
CTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGG
ATAATTCTTTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTT
TTTAAACCATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCAT

>95378_95378_5_TUBD1-CDK12_TUBD1_chr17_57943969_ENST00000346141_CDK12_chr17_37667781_ENST00000430627_length(amino acids)=583AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPP
EPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERN
SGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGT

--------------------------------------------------------------
>95378_95378_6_TUBD1-CDK12_TUBD1_chr17_57943969_ENST00000346141_CDK12_chr17_37667781_ENST00000447079_length(transcript)=6008nt_BP=371nt
CGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGTGGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTG
TGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCACACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGC
ATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAGGTATTGATAGGCATGTATGGCCTCCTTTATCAGGACTTCC
TCCTCTTAGTAAAATGTCTCTCAACAAGGACCTGCATTTTAACACTTCCATTGCTAACTTGGTCATTCTTCGTGGGAAAGATGTGCAAAG
TGCAGATGTGGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCA
GCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTA
GAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAG
AAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCT
AGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCAC
TGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACT
TCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAG
TCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGC
CAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAA
TCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCC
CCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGT
CAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCC
ACAATGCCACAGGAGGAGGCAGCAGCATGTCCTCCTCACATTCTTCCACCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCG
CCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTA
TCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAAC
AGGACTTATGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCC
TTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTG
CAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGA
AGCAGCAATTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCA
GGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGG
AGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATG
AAATCATTTGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGA
CTTACGAAATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAG
AGAATATGGAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTT
CAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATT
TAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGG
CCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAA
CATACTTTTTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTT
GTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTC
TCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAA
AATCGTTGAGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTA
ACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTG
AGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATATTGTTTACACATATATTTTTATGTCAAAAAAA
AAACAAAAACCTTTCAAACAGAGCATTGTGATATTGTCAAAGAGAAAAACAAATCCTGAAGATACATGGAAATGTAACCTAGTTTAGGGT
GGGTATTTTTCTGAAGATACATCAATACCTGACCTTTTTTAAAAAAATAATTTTAAAACAGCATACTGTGAGGAAGAACAGTATTGACAT
ACCCACATCCCAGCATGTGTACCCTGCCAGTTCTTTTAGGGATTTTTCCTCCAAAGAGATTTGGATTTGGTTTTGGTAAAAGGGGTTAAA
TTGTGCTTCCAGGCAAGAACTTTGCCTTATCATAAACAGGAAATGAAAAAGGGAAGGGCTGTCAGGATGGGATAATTTGGGAGGCTTCTC
ATTCTGGCTTCTATTTCTATGTGAGTACCAGCATATAGAGTGTTTTAAAAACAGATACATGTCATATAATTTATCTGCACAGACTTAGAC
CTTCAGGAAACATAGGTTAAGCCCCCTTTTACAAAGAAAAAGTAAACATACTTCAGCATCTTGGAGGGTAGTTTTCAAAACTCAAGTTTC
ATGTTTCAATGCCAAGTTCTTATTTTAAAAAATAAAATCTACTTATAAGAGAAAGGTGCATTACTTAAAAAAAAAAAACTTTAAAGAAAT
GAAAGAAGAACCCTCTTCAGATACTTACTTGAAGACTGTTTTCCCCTGTTAATGAGATATAGCTAGATATCGGTGTGTGTATTTCTTTAT
TATTCTCTGGTTTTTGATCTGGCCTTGCCTCCAGGGCCAAACACTGATTTAGAAAGAGAGCCTTCTAGCTATTTTGGCATTGATGGCTTT
TTATACCAGTGTGTCCAGTTAGATTTACTAGGCTTACTGACATGCTATTGGTAAATCGCATTAAAGTTCATCTGAACCTTCTGTCTGTTG
ACTTCTTAGTCCTCAGACATGGGCCTTTGTGTTTTAGAATATTTGAATTTGAGTTATTGGGCCCCACTCCCTGTTTTTTATTAAAGAACG
TGAGCCTGGGATACTTTCAGAAGTATCTGTTCAATGAAAAAAAGTTGGTTTCCCATCAAATATGAATAAAATTCTCTATATATTTCATTG
TATTTTGGTTATCAGCAGTCATCAATAATGTTTTTCCCTCCCCTCTCCCACCTCTTATTTTTAATTATGCCAAATATCCTAAATAATATA
CTTAAGCCTCCATTCCCTCATCCCTACTAGGGAAGGGGGTGAGTGTATGTGTGAGTGTATGTGTATGTATGATCCCATCTCACCCCCACC
CCCATTTTGGGAGTCTTTTAAAATGAAAACAAAGTTTGGTAGTTTTGACTATTTCTAAAAGCAGAGGAGAAAAAAAAACTTATTTAAATA
TCCTGGAATCTGTATGGAGGAAGAAAAGGTATTTGTTAATTTTTCAGTTACGTTATCTATAAACATGATGGAAGTAAAGGTTTGGCAGAA
TTTCACCTTGACTATTTGAAAATTACAGACCCAATTAATTCCATTCAAAAGTGGTTTTCGTTTTGTTTTAATTATTGTACAATGAGAGAT
ATTGTCTATTAAATACATTATTTTGAACAGATGAGAAATCTGATTCTGTTCATGAGTGGGAGGCAAAACTGGTTTGACCGTGATCATTTT
TGTGGTTTTGAAAACAAATATACTTGACCCAGTTTCCTTAGTTTTTTCTTCAACTGTCCATAGGAACGATAAGTATTTGAAAGCAACATC
AAATCTATACGTTTAAAGCAGGGCAGTTAGCACAAATTTGCAAGTAGAACTTCTATTAGCTTATGCCATAGACATCACCCAACCACTTGT
ATGTGTGTGTGTATATATAATATGCATATATAGTTACCGTGCTAAAATGGTTACCAGCAGGTTTTGAGAGAGAATGCTGCATCAGAAAAG
TGTCAGTTGCCACCTCATTCTCCCTGATTTAGGTTCCTGACACTGATTCCTTTCTCTCTCGTTTTTGACCCCCATTGGGTGTATCTTGTC
TATGTACAGATATTTTGTAATATATTAAATTTTTTTCTTTCAGTTTATAAAAATGGAAAGTGGAGATTGGAAAATTAAATATTTCCTGTT
ACTATACCACTTTTGCTCCATTGCATTTACTTCTTAATCTGTACCCCCTGAGCATATCTAATCATGTATAAAGGACGTTTTTCCTCCACT
TTATCTTAGGGGTTCTCTGTCTCAGAATCATTATAGACTCATTAACTCCCCCTCCCAGCAAAAGGTTATCAGGATTTGAAGAGGTGCTTG
AAAACGCTAGACTAGGAACTAGAGAATAAATGAGTTGGGAAAAACCATGAAATGTGATTTTTTTAAAGTAGAAAAGTTATACAAATAATG
GTACCAAACCATCAAAAGAGTTGAGCTTCATGTACCCTGACTCCTCCTGACAGGAGAGGTAAGTGGGTTTGAGCTCAACTGTCATCAAGG
GAAGTTGGTAAGAGGCTGTTTAGACCCAAAGGATAGTCTTAAACCAGACTTCACCACCCACCCTACCTCAGTTCCCATGTTATTACATGC
AGAGTCAGCATGGGGATTAGTGTACCTACCTTTGCTGAGATTTCCCGATGCGTTGCCAATCCAGAAAGTGAATCAAAAAGTTGTTTAAAA

>95378_95378_6_TUBD1-CDK12_TUBD1_chr17_57943969_ENST00000346141_CDK12_chr17_37667781_ENST00000447079_length(amino acids)=592AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPH
ILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGF
SAIDTDERNSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQ

--------------------------------------------------------------
>95378_95378_7_TUBD1-CDK12_TUBD1_chr17_57943970_ENST00000325752_CDK12_chr17_37667782_ENST00000430627_length(transcript)=4294nt_BP=1353nt
AGCTGGAGCGTTCGGTGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATA
GGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGC
ATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGT
GGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCAC
ACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAG
TTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAAT
ATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAAT
CTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGAT
CAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTG
GTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATG
CCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTG
TGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGAGACTTAATGGAGCATTTAGTTCCCCATCCTG
AATTCAAGATGCTGAGTGTTCGTAACATTCCTCACATGTCTGAGAATTCATTGGCATACACCACATTTACTTGGGCTGGCCTCCTCAAGC
ATTTGAGACAGATGCTCATTTCTAATGCAAAGATGGAAGAAGGTATTGATAGGCATGTATGGCCTCCTTTATCAGGACTTCCTCCTCTTA
GTAAAATGTCTCTCAACAAGGACCTGCATTTTAACACTTCCATTGCTAACTTGGTCATTCTTCGTGGGAAAGATGTGCAAAGTGCAGATG
TGGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGA
TGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGAT
CAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATA
TCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCG
GTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGA
TTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAA
AGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGC
TGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGA
CCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAG
TGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGAT
CCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGAT
GAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCC
ACAGGAGGAGGCAGCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTC
CAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCC
ACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGG
GTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTC
AGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAG
GGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATT
GCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGC
TTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGT
CCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATT
TGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCT
GGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAA
TGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATT
TTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATA
GTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCC
ACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAA
AGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACT
TTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT
GTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCT
TTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACC
ATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAG

>95378_95378_7_TUBD1-CDK12_TUBD1_chr17_57943970_ENST00000325752_CDK12_chr17_37667782_ENST00000430627_length(amino acids)=583AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPP
EPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERN
SGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGT

--------------------------------------------------------------
>95378_95378_8_TUBD1-CDK12_TUBD1_chr17_57943970_ENST00000325752_CDK12_chr17_37667782_ENST00000447079_length(transcript)=6990nt_BP=1353nt
AGCTGGAGCGTTCGGTGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATA
GGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGC
ATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGT
GGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCAC
ACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAG
TTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAAT
ATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAAT
CTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGAT
CAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTG
GTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATG
CCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTG
TGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGAGACTTAATGGAGCATTTAGTTCCCCATCCTG
AATTCAAGATGCTGAGTGTTCGTAACATTCCTCACATGTCTGAGAATTCATTGGCATACACCACATTTACTTGGGCTGGCCTCCTCAAGC
ATTTGAGACAGATGCTCATTTCTAATGCAAAGATGGAAGAAGGTATTGATAGGCATGTATGGCCTCCTTTATCAGGACTTCCTCCTCTTA
GTAAAATGTCTCTCAACAAGGACCTGCATTTTAACACTTCCATTGCTAACTTGGTCATTCTTCGTGGGAAAGATGTGCAAAGTGCAGATG
TGGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGA
TGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGAT
CAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATA
TCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCG
GTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGA
TTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAA
AGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGC
TGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGA
CCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAG
TGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGAT
CCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGAT
GAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCC
ACAGGAGGAGGCAGCAGCATGTCCTCCTCACATTCTTCCACCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCC
ACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCC
TGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTA
TGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCA
GACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCC
AGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAA
TTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCA
CTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGT
TCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATT
TGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAA
ATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATG
GAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTG
AGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTT
TTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTG
ATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTT
TTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACG
TGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTC
TCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTG
AGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCA
ATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGG
TTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATATTGTTTACACATATATTTTTATGTCAAAAAAAAAACAAAA
ACCTTTCAAACAGAGCATTGTGATATTGTCAAAGAGAAAAACAAATCCTGAAGATACATGGAAATGTAACCTAGTTTAGGGTGGGTATTT
TTCTGAAGATACATCAATACCTGACCTTTTTTAAAAAAATAATTTTAAAACAGCATACTGTGAGGAAGAACAGTATTGACATACCCACAT
CCCAGCATGTGTACCCTGCCAGTTCTTTTAGGGATTTTTCCTCCAAAGAGATTTGGATTTGGTTTTGGTAAAAGGGGTTAAATTGTGCTT
CCAGGCAAGAACTTTGCCTTATCATAAACAGGAAATGAAAAAGGGAAGGGCTGTCAGGATGGGATAATTTGGGAGGCTTCTCATTCTGGC
TTCTATTTCTATGTGAGTACCAGCATATAGAGTGTTTTAAAAACAGATACATGTCATATAATTTATCTGCACAGACTTAGACCTTCAGGA
AACATAGGTTAAGCCCCCTTTTACAAAGAAAAAGTAAACATACTTCAGCATCTTGGAGGGTAGTTTTCAAAACTCAAGTTTCATGTTTCA
ATGCCAAGTTCTTATTTTAAAAAATAAAATCTACTTATAAGAGAAAGGTGCATTACTTAAAAAAAAAAAACTTTAAAGAAATGAAAGAAG
AACCCTCTTCAGATACTTACTTGAAGACTGTTTTCCCCTGTTAATGAGATATAGCTAGATATCGGTGTGTGTATTTCTTTATTATTCTCT
GGTTTTTGATCTGGCCTTGCCTCCAGGGCCAAACACTGATTTAGAAAGAGAGCCTTCTAGCTATTTTGGCATTGATGGCTTTTTATACCA
GTGTGTCCAGTTAGATTTACTAGGCTTACTGACATGCTATTGGTAAATCGCATTAAAGTTCATCTGAACCTTCTGTCTGTTGACTTCTTA
GTCCTCAGACATGGGCCTTTGTGTTTTAGAATATTTGAATTTGAGTTATTGGGCCCCACTCCCTGTTTTTTATTAAAGAACGTGAGCCTG
GGATACTTTCAGAAGTATCTGTTCAATGAAAAAAAGTTGGTTTCCCATCAAATATGAATAAAATTCTCTATATATTTCATTGTATTTTGG
TTATCAGCAGTCATCAATAATGTTTTTCCCTCCCCTCTCCCACCTCTTATTTTTAATTATGCCAAATATCCTAAATAATATACTTAAGCC
TCCATTCCCTCATCCCTACTAGGGAAGGGGGTGAGTGTATGTGTGAGTGTATGTGTATGTATGATCCCATCTCACCCCCACCCCCATTTT
GGGAGTCTTTTAAAATGAAAACAAAGTTTGGTAGTTTTGACTATTTCTAAAAGCAGAGGAGAAAAAAAAACTTATTTAAATATCCTGGAA
TCTGTATGGAGGAAGAAAAGGTATTTGTTAATTTTTCAGTTACGTTATCTATAAACATGATGGAAGTAAAGGTTTGGCAGAATTTCACCT
TGACTATTTGAAAATTACAGACCCAATTAATTCCATTCAAAAGTGGTTTTCGTTTTGTTTTAATTATTGTACAATGAGAGATATTGTCTA
TTAAATACATTATTTTGAACAGATGAGAAATCTGATTCTGTTCATGAGTGGGAGGCAAAACTGGTTTGACCGTGATCATTTTTGTGGTTT
TGAAAACAAATATACTTGACCCAGTTTCCTTAGTTTTTTCTTCAACTGTCCATAGGAACGATAAGTATTTGAAAGCAACATCAAATCTAT
ACGTTTAAAGCAGGGCAGTTAGCACAAATTTGCAAGTAGAACTTCTATTAGCTTATGCCATAGACATCACCCAACCACTTGTATGTGTGT
GTGTATATATAATATGCATATATAGTTACCGTGCTAAAATGGTTACCAGCAGGTTTTGAGAGAGAATGCTGCATCAGAAAAGTGTCAGTT
GCCACCTCATTCTCCCTGATTTAGGTTCCTGACACTGATTCCTTTCTCTCTCGTTTTTGACCCCCATTGGGTGTATCTTGTCTATGTACA
GATATTTTGTAATATATTAAATTTTTTTCTTTCAGTTTATAAAAATGGAAAGTGGAGATTGGAAAATTAAATATTTCCTGTTACTATACC
ACTTTTGCTCCATTGCATTTACTTCTTAATCTGTACCCCCTGAGCATATCTAATCATGTATAAAGGACGTTTTTCCTCCACTTTATCTTA
GGGGTTCTCTGTCTCAGAATCATTATAGACTCATTAACTCCCCCTCCCAGCAAAAGGTTATCAGGATTTGAAGAGGTGCTTGAAAACGCT
AGACTAGGAACTAGAGAATAAATGAGTTGGGAAAAACCATGAAATGTGATTTTTTTAAAGTAGAAAAGTTATACAAATAATGGTACCAAA
CCATCAAAAGAGTTGAGCTTCATGTACCCTGACTCCTCCTGACAGGAGAGGTAAGTGGGTTTGAGCTCAACTGTCATCAAGGGAAGTTGG
TAAGAGGCTGTTTAGACCCAAAGGATAGTCTTAAACCAGACTTCACCACCCACCCTACCTCAGTTCCCATGTTATTACATGCAGAGTCAG
CATGGGGATTAGTGTACCTACCTTTGCTGAGATTTCCCGATGCGTTGCCAATCCAGAAAGTGAATCAAAAAGTTGTTTAAAAGTTAAAAT

>95378_95378_8_TUBD1-CDK12_TUBD1_chr17_57943970_ENST00000325752_CDK12_chr17_37667782_ENST00000447079_length(amino acids)=592AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPH
ILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGF
SAIDTDERNSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQ

--------------------------------------------------------------
>95378_95378_9_TUBD1-CDK12_TUBD1_chr17_57943970_ENST00000340993_CDK12_chr17_37667782_ENST00000430627_length(transcript)=4114nt_BP=1173nt
TGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATAGGAAAAAATATATAC
ACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGCATGGTGAGTAGGTTG
GTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGTGGCTCAGCATGTCAA
TTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCACACAGTTCCCAGGGAC
TCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAGTTCCAATTGCCCGGG
CTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAATATGGTCAACATGCAT
GCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAATCTATAATGAACATAA
TCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGATCAGGATTAGGAGCTT
TCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTGGTGAGGTTATTGTTC
AAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATGCCATCCATAAGATCT
GTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTGTGTTCCAGCCTACTT
ATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGTATTGATAGGCATGTATGGCCTCCTTTATCAGGACTTCCTCCTCTTA
GTAAAATGTCTCTCAACAAGGACCTGCATTTTAACACTTCCATTGCTAACTTGGTCATTCTTCGTGGGAAAGATGTGCAAAGTGCAGATG
TGGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGA
TGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGAT
CAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATA
TCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCG
GTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGA
TTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAA
AGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGC
TGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGA
CCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAG
TGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGAT
CCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGAT
GAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCC
ACAGGAGGAGGCAGCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTC
CAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCC
ACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGG
GTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTC
AGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAG
GGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATT
GCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGC
TTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGT
CCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATT
TGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCT
GGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAA
TGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATT
TTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATA
GTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCC
ACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAA
AGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACT
TTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT
GTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCT
TTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACC
ATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAG

>95378_95378_9_TUBD1-CDK12_TUBD1_chr17_57943970_ENST00000340993_CDK12_chr17_37667782_ENST00000430627_length(amino acids)=583AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPP
EPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERN
SGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGT

--------------------------------------------------------------
>95378_95378_10_TUBD1-CDK12_TUBD1_chr17_57943970_ENST00000340993_CDK12_chr17_37667782_ENST00000447079_length(transcript)=6810nt_BP=1173nt
TGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATAGGAAAAAATATATAC
ACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGCATGGTGAGTAGGTTG
GTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGTGGCTCAGCATGTCAA
TTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCACACAGTTCCCAGGGAC
TCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAGTTCCAATTGCCCGGG
CTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAATATGGTCAACATGCAT
GCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAATCTATAATGAACATAA
TCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGATCAGGATTAGGAGCTT
TCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTGGTGAGGTTATTGTTC
AAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATGCCATCCATAAGATCT
GTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTGTGTTCCAGCCTACTT
ATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGTATTGATAGGCATGTATGGCCTCCTTTATCAGGACTTCCTCCTCTTA
GTAAAATGTCTCTCAACAAGGACCTGCATTTTAACACTTCCATTGCTAACTTGGTCATTCTTCGTGGGAAAGATGTGCAAAGTGCAGATG
TGGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGA
TGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGAT
CAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATA
TCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCG
GTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGA
TTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAA
AGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGC
TGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGA
CCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAG
TGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGAT
CCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGAT
GAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCC
ACAGGAGGAGGCAGCAGCATGTCCTCCTCACATTCTTCCACCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCC
ACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCC
TGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTA
TGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCA
GACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCC
AGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAA
TTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCA
CTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGT
TCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATT
TGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAA
ATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATG
GAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTG
AGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTT
TTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTG
ATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTT
TTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACG
TGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTC
TCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTG
AGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCA
ATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGG
TTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATATTGTTTACACATATATTTTTATGTCAAAAAAAAAACAAAA
ACCTTTCAAACAGAGCATTGTGATATTGTCAAAGAGAAAAACAAATCCTGAAGATACATGGAAATGTAACCTAGTTTAGGGTGGGTATTT
TTCTGAAGATACATCAATACCTGACCTTTTTTAAAAAAATAATTTTAAAACAGCATACTGTGAGGAAGAACAGTATTGACATACCCACAT
CCCAGCATGTGTACCCTGCCAGTTCTTTTAGGGATTTTTCCTCCAAAGAGATTTGGATTTGGTTTTGGTAAAAGGGGTTAAATTGTGCTT
CCAGGCAAGAACTTTGCCTTATCATAAACAGGAAATGAAAAAGGGAAGGGCTGTCAGGATGGGATAATTTGGGAGGCTTCTCATTCTGGC
TTCTATTTCTATGTGAGTACCAGCATATAGAGTGTTTTAAAAACAGATACATGTCATATAATTTATCTGCACAGACTTAGACCTTCAGGA
AACATAGGTTAAGCCCCCTTTTACAAAGAAAAAGTAAACATACTTCAGCATCTTGGAGGGTAGTTTTCAAAACTCAAGTTTCATGTTTCA
ATGCCAAGTTCTTATTTTAAAAAATAAAATCTACTTATAAGAGAAAGGTGCATTACTTAAAAAAAAAAAACTTTAAAGAAATGAAAGAAG
AACCCTCTTCAGATACTTACTTGAAGACTGTTTTCCCCTGTTAATGAGATATAGCTAGATATCGGTGTGTGTATTTCTTTATTATTCTCT
GGTTTTTGATCTGGCCTTGCCTCCAGGGCCAAACACTGATTTAGAAAGAGAGCCTTCTAGCTATTTTGGCATTGATGGCTTTTTATACCA
GTGTGTCCAGTTAGATTTACTAGGCTTACTGACATGCTATTGGTAAATCGCATTAAAGTTCATCTGAACCTTCTGTCTGTTGACTTCTTA
GTCCTCAGACATGGGCCTTTGTGTTTTAGAATATTTGAATTTGAGTTATTGGGCCCCACTCCCTGTTTTTTATTAAAGAACGTGAGCCTG
GGATACTTTCAGAAGTATCTGTTCAATGAAAAAAAGTTGGTTTCCCATCAAATATGAATAAAATTCTCTATATATTTCATTGTATTTTGG
TTATCAGCAGTCATCAATAATGTTTTTCCCTCCCCTCTCCCACCTCTTATTTTTAATTATGCCAAATATCCTAAATAATATACTTAAGCC
TCCATTCCCTCATCCCTACTAGGGAAGGGGGTGAGTGTATGTGTGAGTGTATGTGTATGTATGATCCCATCTCACCCCCACCCCCATTTT
GGGAGTCTTTTAAAATGAAAACAAAGTTTGGTAGTTTTGACTATTTCTAAAAGCAGAGGAGAAAAAAAAACTTATTTAAATATCCTGGAA
TCTGTATGGAGGAAGAAAAGGTATTTGTTAATTTTTCAGTTACGTTATCTATAAACATGATGGAAGTAAAGGTTTGGCAGAATTTCACCT
TGACTATTTGAAAATTACAGACCCAATTAATTCCATTCAAAAGTGGTTTTCGTTTTGTTTTAATTATTGTACAATGAGAGATATTGTCTA
TTAAATACATTATTTTGAACAGATGAGAAATCTGATTCTGTTCATGAGTGGGAGGCAAAACTGGTTTGACCGTGATCATTTTTGTGGTTT
TGAAAACAAATATACTTGACCCAGTTTCCTTAGTTTTTTCTTCAACTGTCCATAGGAACGATAAGTATTTGAAAGCAACATCAAATCTAT
ACGTTTAAAGCAGGGCAGTTAGCACAAATTTGCAAGTAGAACTTCTATTAGCTTATGCCATAGACATCACCCAACCACTTGTATGTGTGT
GTGTATATATAATATGCATATATAGTTACCGTGCTAAAATGGTTACCAGCAGGTTTTGAGAGAGAATGCTGCATCAGAAAAGTGTCAGTT
GCCACCTCATTCTCCCTGATTTAGGTTCCTGACACTGATTCCTTTCTCTCTCGTTTTTGACCCCCATTGGGTGTATCTTGTCTATGTACA
GATATTTTGTAATATATTAAATTTTTTTCTTTCAGTTTATAAAAATGGAAAGTGGAGATTGGAAAATTAAATATTTCCTGTTACTATACC
ACTTTTGCTCCATTGCATTTACTTCTTAATCTGTACCCCCTGAGCATATCTAATCATGTATAAAGGACGTTTTTCCTCCACTTTATCTTA
GGGGTTCTCTGTCTCAGAATCATTATAGACTCATTAACTCCCCCTCCCAGCAAAAGGTTATCAGGATTTGAAGAGGTGCTTGAAAACGCT
AGACTAGGAACTAGAGAATAAATGAGTTGGGAAAAACCATGAAATGTGATTTTTTTAAAGTAGAAAAGTTATACAAATAATGGTACCAAA
CCATCAAAAGAGTTGAGCTTCATGTACCCTGACTCCTCCTGACAGGAGAGGTAAGTGGGTTTGAGCTCAACTGTCATCAAGGGAAGTTGG
TAAGAGGCTGTTTAGACCCAAAGGATAGTCTTAAACCAGACTTCACCACCCACCCTACCTCAGTTCCCATGTTATTACATGCAGAGTCAG
CATGGGGATTAGTGTACCTACCTTTGCTGAGATTTCCCGATGCGTTGCCAATCCAGAAAGTGAATCAAAAAGTTGTTTAAAAGTTAAAAT

>95378_95378_10_TUBD1-CDK12_TUBD1_chr17_57943970_ENST00000340993_CDK12_chr17_37667782_ENST00000447079_length(amino acids)=592AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPH
ILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGF
SAIDTDERNSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQ

--------------------------------------------------------------
>95378_95378_11_TUBD1-CDK12_TUBD1_chr17_57943970_ENST00000346141_CDK12_chr17_37667782_ENST00000430627_length(transcript)=3312nt_BP=371nt
CGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGTGGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTG
TGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCACACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGC
ATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAGGTATTGATAGGCATGTATGGCCTCCTTTATCAGGACTTCC
TCCTCTTAGTAAAATGTCTCTCAACAAGGACCTGCATTTTAACACTTCCATTGCTAACTTGGTCATTCTTCGTGGGAAAGATGTGCAAAG
TGCAGATGTGGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCA
GCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTA
GAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAG
AAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCT
AGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCAC
TGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACT
TCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAG
TCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGC
CAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAA
TCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCC
CCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGT
CAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCC
ACAATGCCACAGGAGGAGGCAGCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGC
GATCTTTCCAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGC
CACCTGCCACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCT
GAAACAGGGTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGG
ACCTTCTCAGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGT
TTTGCCAGGGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAG
ACCAAATTGCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAG
TCTTCTGCTTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGAC
TTCAGTGTCCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCA
TCTGCATTTGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAG
TTCCCCCTGGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGA
AAAGTAAATGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCT
CTTTGATTTTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAA
AGAGAATAGTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTT
TCCTCTCCACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTC
ATCCTTAAAGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTA
GGTAGACTTTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT
CTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGG
ATAATTCTTTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTT
TTTAAACCATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCAT

>95378_95378_11_TUBD1-CDK12_TUBD1_chr17_57943970_ENST00000346141_CDK12_chr17_37667782_ENST00000430627_length(amino acids)=583AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPP
EPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERN
SGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGT

--------------------------------------------------------------
>95378_95378_12_TUBD1-CDK12_TUBD1_chr17_57943970_ENST00000346141_CDK12_chr17_37667782_ENST00000447079_length(transcript)=6008nt_BP=371nt
CGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGTGGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTG
TGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCACACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGC
ATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAGGTATTGATAGGCATGTATGGCCTCCTTTATCAGGACTTCC
TCCTCTTAGTAAAATGTCTCTCAACAAGGACCTGCATTTTAACACTTCCATTGCTAACTTGGTCATTCTTCGTGGGAAAGATGTGCAAAG
TGCAGATGTGGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCA
GCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTA
GAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAG
AAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCT
AGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCAC
TGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACT
TCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAG
TCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGC
CAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAA
TCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCC
CCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGT
CAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCC
ACAATGCCACAGGAGGAGGCAGCAGCATGTCCTCCTCACATTCTTCCACCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCG
CCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTA
TCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAAC
AGGACTTATGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCC
TTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTG
CAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGA
AGCAGCAATTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCA
GGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGG
AGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATG
AAATCATTTGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGA
CTTACGAAATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAG
AGAATATGGAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTT
CAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATT
TAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGG
CCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAA
CATACTTTTTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTT
GTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTC
TCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAA
AATCGTTGAGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTA
ACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTG
AGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATATTGTTTACACATATATTTTTATGTCAAAAAAA
AAACAAAAACCTTTCAAACAGAGCATTGTGATATTGTCAAAGAGAAAAACAAATCCTGAAGATACATGGAAATGTAACCTAGTTTAGGGT
GGGTATTTTTCTGAAGATACATCAATACCTGACCTTTTTTAAAAAAATAATTTTAAAACAGCATACTGTGAGGAAGAACAGTATTGACAT
ACCCACATCCCAGCATGTGTACCCTGCCAGTTCTTTTAGGGATTTTTCCTCCAAAGAGATTTGGATTTGGTTTTGGTAAAAGGGGTTAAA
TTGTGCTTCCAGGCAAGAACTTTGCCTTATCATAAACAGGAAATGAAAAAGGGAAGGGCTGTCAGGATGGGATAATTTGGGAGGCTTCTC
ATTCTGGCTTCTATTTCTATGTGAGTACCAGCATATAGAGTGTTTTAAAAACAGATACATGTCATATAATTTATCTGCACAGACTTAGAC
CTTCAGGAAACATAGGTTAAGCCCCCTTTTACAAAGAAAAAGTAAACATACTTCAGCATCTTGGAGGGTAGTTTTCAAAACTCAAGTTTC
ATGTTTCAATGCCAAGTTCTTATTTTAAAAAATAAAATCTACTTATAAGAGAAAGGTGCATTACTTAAAAAAAAAAAACTTTAAAGAAAT
GAAAGAAGAACCCTCTTCAGATACTTACTTGAAGACTGTTTTCCCCTGTTAATGAGATATAGCTAGATATCGGTGTGTGTATTTCTTTAT
TATTCTCTGGTTTTTGATCTGGCCTTGCCTCCAGGGCCAAACACTGATTTAGAAAGAGAGCCTTCTAGCTATTTTGGCATTGATGGCTTT
TTATACCAGTGTGTCCAGTTAGATTTACTAGGCTTACTGACATGCTATTGGTAAATCGCATTAAAGTTCATCTGAACCTTCTGTCTGTTG
ACTTCTTAGTCCTCAGACATGGGCCTTTGTGTTTTAGAATATTTGAATTTGAGTTATTGGGCCCCACTCCCTGTTTTTTATTAAAGAACG
TGAGCCTGGGATACTTTCAGAAGTATCTGTTCAATGAAAAAAAGTTGGTTTCCCATCAAATATGAATAAAATTCTCTATATATTTCATTG
TATTTTGGTTATCAGCAGTCATCAATAATGTTTTTCCCTCCCCTCTCCCACCTCTTATTTTTAATTATGCCAAATATCCTAAATAATATA
CTTAAGCCTCCATTCCCTCATCCCTACTAGGGAAGGGGGTGAGTGTATGTGTGAGTGTATGTGTATGTATGATCCCATCTCACCCCCACC
CCCATTTTGGGAGTCTTTTAAAATGAAAACAAAGTTTGGTAGTTTTGACTATTTCTAAAAGCAGAGGAGAAAAAAAAACTTATTTAAATA
TCCTGGAATCTGTATGGAGGAAGAAAAGGTATTTGTTAATTTTTCAGTTACGTTATCTATAAACATGATGGAAGTAAAGGTTTGGCAGAA
TTTCACCTTGACTATTTGAAAATTACAGACCCAATTAATTCCATTCAAAAGTGGTTTTCGTTTTGTTTTAATTATTGTACAATGAGAGAT
ATTGTCTATTAAATACATTATTTTGAACAGATGAGAAATCTGATTCTGTTCATGAGTGGGAGGCAAAACTGGTTTGACCGTGATCATTTT
TGTGGTTTTGAAAACAAATATACTTGACCCAGTTTCCTTAGTTTTTTCTTCAACTGTCCATAGGAACGATAAGTATTTGAAAGCAACATC
AAATCTATACGTTTAAAGCAGGGCAGTTAGCACAAATTTGCAAGTAGAACTTCTATTAGCTTATGCCATAGACATCACCCAACCACTTGT
ATGTGTGTGTGTATATATAATATGCATATATAGTTACCGTGCTAAAATGGTTACCAGCAGGTTTTGAGAGAGAATGCTGCATCAGAAAAG
TGTCAGTTGCCACCTCATTCTCCCTGATTTAGGTTCCTGACACTGATTCCTTTCTCTCTCGTTTTTGACCCCCATTGGGTGTATCTTGTC
TATGTACAGATATTTTGTAATATATTAAATTTTTTTCTTTCAGTTTATAAAAATGGAAAGTGGAGATTGGAAAATTAAATATTTCCTGTT
ACTATACCACTTTTGCTCCATTGCATTTACTTCTTAATCTGTACCCCCTGAGCATATCTAATCATGTATAAAGGACGTTTTTCCTCCACT
TTATCTTAGGGGTTCTCTGTCTCAGAATCATTATAGACTCATTAACTCCCCCTCCCAGCAAAAGGTTATCAGGATTTGAAGAGGTGCTTG
AAAACGCTAGACTAGGAACTAGAGAATAAATGAGTTGGGAAAAACCATGAAATGTGATTTTTTTAAAGTAGAAAAGTTATACAAATAATG
GTACCAAACCATCAAAAGAGTTGAGCTTCATGTACCCTGACTCCTCCTGACAGGAGAGGTAAGTGGGTTTGAGCTCAACTGTCATCAAGG
GAAGTTGGTAAGAGGCTGTTTAGACCCAAAGGATAGTCTTAAACCAGACTTCACCACCCACCCTACCTCAGTTCCCATGTTATTACATGC
AGAGTCAGCATGGGGATTAGTGTACCTACCTTTGCTGAGATTTCCCGATGCGTTGCCAATCCAGAAAGTGAATCAAAAAGTTGTTTAAAA

>95378_95378_12_TUBD1-CDK12_TUBD1_chr17_57943970_ENST00000346141_CDK12_chr17_37667782_ENST00000447079_length(amino acids)=592AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPH
ILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGF
SAIDTDERNSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQ

--------------------------------------------------------------
>95378_95378_13_TUBD1-CDK12_TUBD1_chr17_57951899_ENST00000325752_CDK12_chr17_37667781_ENST00000430627_length(transcript)=4153nt_BP=1212nt
AGCTGGAGCGTTCGGTGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATA
GGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGC
ATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGT
GGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCAC
ACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAG
TTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAAT
ATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAAT
CTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGAT
CAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTG
GTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATG
CCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTG
TGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGAGACTTAATGGAGCATTTAGTTCCCCATCCTG
AATTCAAGATGCTGAGTGTTCGTAACATTCCTCACATGTCTGAGAATTCATTGGCATACACCACATTTACTTGGGCTGGCCTCCTCAAGC
ATTTGAGACAGATGCTCATTTCTAATGCAAAGATGGAAGAAGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGA
ACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTAT
TTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAA
ACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGA
TTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACT
CAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGT
TGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGC
ACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGA
ATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGA
GATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCC
AGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGA
CATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAA
CAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCCACAGGAGGAGGCAGCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACC
GCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACT
TTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCC
AAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGA
ATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTC
AGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGA
GGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGG
AGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAG
AGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTT
AATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAG
GCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAA
GTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACA
GTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTT
AATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGA
GTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCT
TGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCA
GGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTC
TCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGG
AAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTC
TGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCT
GCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATATTGTTTACACATATATTTTTATGTCAAA

>95378_95378_13_TUBD1-CDK12_TUBD1_chr17_57951899_ENST00000325752_CDK12_chr17_37667781_ENST00000430627_length(amino acids)=583AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPP
EPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERN
SGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGT

--------------------------------------------------------------
>95378_95378_14_TUBD1-CDK12_TUBD1_chr17_57951899_ENST00000325752_CDK12_chr17_37667781_ENST00000447079_length(transcript)=6849nt_BP=1212nt
AGCTGGAGCGTTCGGTGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATA
GGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGC
ATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGT
GGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCAC
ACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAG
TTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAAT
ATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAAT
CTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGAT
CAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTG
GTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATG
CCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTG
TGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGAGACTTAATGGAGCATTTAGTTCCCCATCCTG
AATTCAAGATGCTGAGTGTTCGTAACATTCCTCACATGTCTGAGAATTCATTGGCATACACCACATTTACTTGGGCTGGCCTCCTCAAGC
ATTTGAGACAGATGCTCATTTCTAATGCAAAGATGGAAGAAGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGA
ACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTAT
TTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAA
ACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGA
TTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACT
CAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGT
TGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGC
ACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGA
ATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGA
GATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCC
AGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGA
CATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAA
CAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCCACAGGAGGAGGCAGCAGCATGTCCTCCTCACATTCTTCCACCAGAGAAGAG
GCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACCC
AGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACC
AATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATGA
ACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGGA
GTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGGT
GGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGCC
AGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGCC
TACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCCA
TCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTTG
TATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATTT
ACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGCA
CTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGATT
GTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCTC
TTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAAG
TGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAGA
TACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTTG
CTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGT
TTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAAA
GGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATTT
GTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATAT
TGTTTACACATATATTTTTATGTCAAAAAAAAAACAAAAACCTTTCAAACAGAGCATTGTGATATTGTCAAAGAGAAAAACAAATCCTGA
AGATACATGGAAATGTAACCTAGTTTAGGGTGGGTATTTTTCTGAAGATACATCAATACCTGACCTTTTTTAAAAAAATAATTTTAAAAC
AGCATACTGTGAGGAAGAACAGTATTGACATACCCACATCCCAGCATGTGTACCCTGCCAGTTCTTTTAGGGATTTTTCCTCCAAAGAGA
TTTGGATTTGGTTTTGGTAAAAGGGGTTAAATTGTGCTTCCAGGCAAGAACTTTGCCTTATCATAAACAGGAAATGAAAAAGGGAAGGGC
TGTCAGGATGGGATAATTTGGGAGGCTTCTCATTCTGGCTTCTATTTCTATGTGAGTACCAGCATATAGAGTGTTTTAAAAACAGATACA
TGTCATATAATTTATCTGCACAGACTTAGACCTTCAGGAAACATAGGTTAAGCCCCCTTTTACAAAGAAAAAGTAAACATACTTCAGCAT
CTTGGAGGGTAGTTTTCAAAACTCAAGTTTCATGTTTCAATGCCAAGTTCTTATTTTAAAAAATAAAATCTACTTATAAGAGAAAGGTGC
ATTACTTAAAAAAAAAAAACTTTAAAGAAATGAAAGAAGAACCCTCTTCAGATACTTACTTGAAGACTGTTTTCCCCTGTTAATGAGATA
TAGCTAGATATCGGTGTGTGTATTTCTTTATTATTCTCTGGTTTTTGATCTGGCCTTGCCTCCAGGGCCAAACACTGATTTAGAAAGAGA
GCCTTCTAGCTATTTTGGCATTGATGGCTTTTTATACCAGTGTGTCCAGTTAGATTTACTAGGCTTACTGACATGCTATTGGTAAATCGC
ATTAAAGTTCATCTGAACCTTCTGTCTGTTGACTTCTTAGTCCTCAGACATGGGCCTTTGTGTTTTAGAATATTTGAATTTGAGTTATTG
GGCCCCACTCCCTGTTTTTTATTAAAGAACGTGAGCCTGGGATACTTTCAGAAGTATCTGTTCAATGAAAAAAAGTTGGTTTCCCATCAA
ATATGAATAAAATTCTCTATATATTTCATTGTATTTTGGTTATCAGCAGTCATCAATAATGTTTTTCCCTCCCCTCTCCCACCTCTTATT
TTTAATTATGCCAAATATCCTAAATAATATACTTAAGCCTCCATTCCCTCATCCCTACTAGGGAAGGGGGTGAGTGTATGTGTGAGTGTA
TGTGTATGTATGATCCCATCTCACCCCCACCCCCATTTTGGGAGTCTTTTAAAATGAAAACAAAGTTTGGTAGTTTTGACTATTTCTAAA
AGCAGAGGAGAAAAAAAAACTTATTTAAATATCCTGGAATCTGTATGGAGGAAGAAAAGGTATTTGTTAATTTTTCAGTTACGTTATCTA
TAAACATGATGGAAGTAAAGGTTTGGCAGAATTTCACCTTGACTATTTGAAAATTACAGACCCAATTAATTCCATTCAAAAGTGGTTTTC
GTTTTGTTTTAATTATTGTACAATGAGAGATATTGTCTATTAAATACATTATTTTGAACAGATGAGAAATCTGATTCTGTTCATGAGTGG
GAGGCAAAACTGGTTTGACCGTGATCATTTTTGTGGTTTTGAAAACAAATATACTTGACCCAGTTTCCTTAGTTTTTTCTTCAACTGTCC
ATAGGAACGATAAGTATTTGAAAGCAACATCAAATCTATACGTTTAAAGCAGGGCAGTTAGCACAAATTTGCAAGTAGAACTTCTATTAG
CTTATGCCATAGACATCACCCAACCACTTGTATGTGTGTGTGTATATATAATATGCATATATAGTTACCGTGCTAAAATGGTTACCAGCA
GGTTTTGAGAGAGAATGCTGCATCAGAAAAGTGTCAGTTGCCACCTCATTCTCCCTGATTTAGGTTCCTGACACTGATTCCTTTCTCTCT
CGTTTTTGACCCCCATTGGGTGTATCTTGTCTATGTACAGATATTTTGTAATATATTAAATTTTTTTCTTTCAGTTTATAAAAATGGAAA
GTGGAGATTGGAAAATTAAATATTTCCTGTTACTATACCACTTTTGCTCCATTGCATTTACTTCTTAATCTGTACCCCCTGAGCATATCT
AATCATGTATAAAGGACGTTTTTCCTCCACTTTATCTTAGGGGTTCTCTGTCTCAGAATCATTATAGACTCATTAACTCCCCCTCCCAGC
AAAAGGTTATCAGGATTTGAAGAGGTGCTTGAAAACGCTAGACTAGGAACTAGAGAATAAATGAGTTGGGAAAAACCATGAAATGTGATT
TTTTTAAAGTAGAAAAGTTATACAAATAATGGTACCAAACCATCAAAAGAGTTGAGCTTCATGTACCCTGACTCCTCCTGACAGGAGAGG
TAAGTGGGTTTGAGCTCAACTGTCATCAAGGGAAGTTGGTAAGAGGCTGTTTAGACCCAAAGGATAGTCTTAAACCAGACTTCACCACCC
ACCCTACCTCAGTTCCCATGTTATTACATGCAGAGTCAGCATGGGGATTAGTGTACCTACCTTTGCTGAGATTTCCCGATGCGTTGCCAA
TCCAGAAAGTGAATCAAAAAGTTGTTTAAAAGTTAAAATCTCTATTGTTTCCAAAATCTTTCCCATCTCCACCTGAAGACAGAATTGCTT

>95378_95378_14_TUBD1-CDK12_TUBD1_chr17_57951899_ENST00000325752_CDK12_chr17_37667781_ENST00000447079_length(amino acids)=592AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPH
ILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGF
SAIDTDERNSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQ

--------------------------------------------------------------
>95378_95378_15_TUBD1-CDK12_TUBD1_chr17_57951899_ENST00000394239_CDK12_chr17_37667781_ENST00000430627_length(transcript)=4076nt_BP=1135nt
ATCTTTCTGAATAGGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAA
AGTGAGCATGCGCATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAAT
ACACCTAGTTTGTGGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTG
CTTAGTGACTCACACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAG
GAGGAGAATGGAGTTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCT
GGCCAATGGAAATATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCC
AGGCATGAAGAATCTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCT
GGGGGCACAGGATCAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGG
CCTTATGGAACTGGTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTT
CATGAGAATGATGCCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACAT
CAGCTGGGAAGTGTGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGAGACTTAATGGAGCATTTA
GTTCCCCATCCTGAATTCAAGATGCTGAGTGTTCGTAACATTCCTCACATGTCTGAGAATTCATTGGCATACACCACATTTACTTGGGCT
GGCCTCCTCAAGCATTTGAGACAGATGCTCATTTCTAATGCAAAGATGGAAGAAGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGT
ACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCA
CAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGC
CTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTT
CTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTA
AAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGC
GACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGA
ACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACAGC
TGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCC
ACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAG
AGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAA
GCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACA
ACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCCACAGGAGGAGGCAGCAGAGAAGAGGCCCCCTGAGCCCC
CCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCG
CCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCA
CCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTC
CAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACC
AGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCAT
TCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGG
CCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCAC
CAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGT
TCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCAC
TTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATTTACTTCAACTCTACC
TTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAA
GAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTT
TCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTA
TAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCC
CCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCC
TGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCT
CTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGA
GGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTC
TTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAG
CTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATATTGTTTACACATATA

>95378_95378_15_TUBD1-CDK12_TUBD1_chr17_57951899_ENST00000394239_CDK12_chr17_37667781_ENST00000430627_length(amino acids)=583AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPP
EPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERN
SGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGT

--------------------------------------------------------------
>95378_95378_16_TUBD1-CDK12_TUBD1_chr17_57951899_ENST00000394239_CDK12_chr17_37667781_ENST00000447079_length(transcript)=6772nt_BP=1135nt
ATCTTTCTGAATAGGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAA
AGTGAGCATGCGCATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAAT
ACACCTAGTTTGTGGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTG
CTTAGTGACTCACACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAG
GAGGAGAATGGAGTTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCT
GGCCAATGGAAATATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCC
AGGCATGAAGAATCTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCT
GGGGGCACAGGATCAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGG
CCTTATGGAACTGGTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTT
CATGAGAATGATGCCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACAT
CAGCTGGGAAGTGTGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGAGACTTAATGGAGCATTTA
GTTCCCCATCCTGAATTCAAGATGCTGAGTGTTCGTAACATTCCTCACATGTCTGAGAATTCATTGGCATACACCACATTTACTTGGGCT
GGCCTCCTCAAGCATTTGAGACAGATGCTCATTTCTAATGCAAAGATGGAAGAAGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGT
ACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCA
CAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGC
CTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTT
CTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTA
AAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGC
GACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGA
ACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACAGC
TGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCC
ACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAG
AGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAA
GCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACA
ACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCCACAGGAGGAGGCAGCAGCATGTCCTCCTCACATTCTTC
CACCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCC
AGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACC
AGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCA
TTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGA
GCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAG
CGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATG
GGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAAC
TCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATT
CCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCA
AAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTAT
AGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAG
TTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTT
GGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAA
ATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACA
TTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCA
CTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCT
CTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGC
TCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTT
GAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATG
GGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACA
GCATTTAGCATATTGTTTACACATATATTTTTATGTCAAAAAAAAAACAAAAACCTTTCAAACAGAGCATTGTGATATTGTCAAAGAGAA
AAACAAATCCTGAAGATACATGGAAATGTAACCTAGTTTAGGGTGGGTATTTTTCTGAAGATACATCAATACCTGACCTTTTTTAAAAAA
ATAATTTTAAAACAGCATACTGTGAGGAAGAACAGTATTGACATACCCACATCCCAGCATGTGTACCCTGCCAGTTCTTTTAGGGATTTT
TCCTCCAAAGAGATTTGGATTTGGTTTTGGTAAAAGGGGTTAAATTGTGCTTCCAGGCAAGAACTTTGCCTTATCATAAACAGGAAATGA
AAAAGGGAAGGGCTGTCAGGATGGGATAATTTGGGAGGCTTCTCATTCTGGCTTCTATTTCTATGTGAGTACCAGCATATAGAGTGTTTT
AAAAACAGATACATGTCATATAATTTATCTGCACAGACTTAGACCTTCAGGAAACATAGGTTAAGCCCCCTTTTACAAAGAAAAAGTAAA
CATACTTCAGCATCTTGGAGGGTAGTTTTCAAAACTCAAGTTTCATGTTTCAATGCCAAGTTCTTATTTTAAAAAATAAAATCTACTTAT
AAGAGAAAGGTGCATTACTTAAAAAAAAAAAACTTTAAAGAAATGAAAGAAGAACCCTCTTCAGATACTTACTTGAAGACTGTTTTCCCC
TGTTAATGAGATATAGCTAGATATCGGTGTGTGTATTTCTTTATTATTCTCTGGTTTTTGATCTGGCCTTGCCTCCAGGGCCAAACACTG
ATTTAGAAAGAGAGCCTTCTAGCTATTTTGGCATTGATGGCTTTTTATACCAGTGTGTCCAGTTAGATTTACTAGGCTTACTGACATGCT
ATTGGTAAATCGCATTAAAGTTCATCTGAACCTTCTGTCTGTTGACTTCTTAGTCCTCAGACATGGGCCTTTGTGTTTTAGAATATTTGA
ATTTGAGTTATTGGGCCCCACTCCCTGTTTTTTATTAAAGAACGTGAGCCTGGGATACTTTCAGAAGTATCTGTTCAATGAAAAAAAGTT
GGTTTCCCATCAAATATGAATAAAATTCTCTATATATTTCATTGTATTTTGGTTATCAGCAGTCATCAATAATGTTTTTCCCTCCCCTCT
CCCACCTCTTATTTTTAATTATGCCAAATATCCTAAATAATATACTTAAGCCTCCATTCCCTCATCCCTACTAGGGAAGGGGGTGAGTGT
ATGTGTGAGTGTATGTGTATGTATGATCCCATCTCACCCCCACCCCCATTTTGGGAGTCTTTTAAAATGAAAACAAAGTTTGGTAGTTTT
GACTATTTCTAAAAGCAGAGGAGAAAAAAAAACTTATTTAAATATCCTGGAATCTGTATGGAGGAAGAAAAGGTATTTGTTAATTTTTCA
GTTACGTTATCTATAAACATGATGGAAGTAAAGGTTTGGCAGAATTTCACCTTGACTATTTGAAAATTACAGACCCAATTAATTCCATTC
AAAAGTGGTTTTCGTTTTGTTTTAATTATTGTACAATGAGAGATATTGTCTATTAAATACATTATTTTGAACAGATGAGAAATCTGATTC
TGTTCATGAGTGGGAGGCAAAACTGGTTTGACCGTGATCATTTTTGTGGTTTTGAAAACAAATATACTTGACCCAGTTTCCTTAGTTTTT
TCTTCAACTGTCCATAGGAACGATAAGTATTTGAAAGCAACATCAAATCTATACGTTTAAAGCAGGGCAGTTAGCACAAATTTGCAAGTA
GAACTTCTATTAGCTTATGCCATAGACATCACCCAACCACTTGTATGTGTGTGTGTATATATAATATGCATATATAGTTACCGTGCTAAA
ATGGTTACCAGCAGGTTTTGAGAGAGAATGCTGCATCAGAAAAGTGTCAGTTGCCACCTCATTCTCCCTGATTTAGGTTCCTGACACTGA
TTCCTTTCTCTCTCGTTTTTGACCCCCATTGGGTGTATCTTGTCTATGTACAGATATTTTGTAATATATTAAATTTTTTTCTTTCAGTTT
ATAAAAATGGAAAGTGGAGATTGGAAAATTAAATATTTCCTGTTACTATACCACTTTTGCTCCATTGCATTTACTTCTTAATCTGTACCC
CCTGAGCATATCTAATCATGTATAAAGGACGTTTTTCCTCCACTTTATCTTAGGGGTTCTCTGTCTCAGAATCATTATAGACTCATTAAC
TCCCCCTCCCAGCAAAAGGTTATCAGGATTTGAAGAGGTGCTTGAAAACGCTAGACTAGGAACTAGAGAATAAATGAGTTGGGAAAAACC
ATGAAATGTGATTTTTTTAAAGTAGAAAAGTTATACAAATAATGGTACCAAACCATCAAAAGAGTTGAGCTTCATGTACCCTGACTCCTC
CTGACAGGAGAGGTAAGTGGGTTTGAGCTCAACTGTCATCAAGGGAAGTTGGTAAGAGGCTGTTTAGACCCAAAGGATAGTCTTAAACCA
GACTTCACCACCCACCCTACCTCAGTTCCCATGTTATTACATGCAGAGTCAGCATGGGGATTAGTGTACCTACCTTTGCTGAGATTTCCC
GATGCGTTGCCAATCCAGAAAGTGAATCAAAAAGTTGTTTAAAAGTTAAAATCTCTATTGTTTCCAAAATCTTTCCCATCTCCACCTGAA

>95378_95378_16_TUBD1-CDK12_TUBD1_chr17_57951899_ENST00000394239_CDK12_chr17_37667781_ENST00000447079_length(amino acids)=592AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPH
ILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGF
SAIDTDERNSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQ

--------------------------------------------------------------
>95378_95378_17_TUBD1-CDK12_TUBD1_chr17_57951900_ENST00000325752_CDK12_chr17_37667782_ENST00000430627_length(transcript)=4153nt_BP=1212nt
AGCTGGAGCGTTCGGTGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATA
GGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGC
ATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGT
GGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCAC
ACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAG
TTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAAT
ATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAAT
CTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGAT
CAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTG
GTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATG
CCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTG
TGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGAGACTTAATGGAGCATTTAGTTCCCCATCCTG
AATTCAAGATGCTGAGTGTTCGTAACATTCCTCACATGTCTGAGAATTCATTGGCATACACCACATTTACTTGGGCTGGCCTCCTCAAGC
ATTTGAGACAGATGCTCATTTCTAATGCAAAGATGGAAGAAGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGA
ACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTAT
TTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAA
ACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGA
TTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACT
CAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGT
TGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGC
ACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGA
ATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGA
GATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCC
AGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGA
CATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAA
CAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCCACAGGAGGAGGCAGCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACC
GCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACT
TTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCC
AAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGA
ATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTC
AGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGA
GGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGG
AGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAG
AGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTT
AATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAG
GCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAA
GTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACA
GTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTT
AATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGA
GTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCT
TGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCA
GGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTC
TCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGG
AAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTC
TGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCT
GCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATATTGTTTACACATATATTTTTATGTCAAA

>95378_95378_17_TUBD1-CDK12_TUBD1_chr17_57951900_ENST00000325752_CDK12_chr17_37667782_ENST00000430627_length(amino acids)=583AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPP
EPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERN
SGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGT

--------------------------------------------------------------
>95378_95378_18_TUBD1-CDK12_TUBD1_chr17_57951900_ENST00000325752_CDK12_chr17_37667782_ENST00000447079_length(transcript)=6849nt_BP=1212nt
AGCTGGAGCGTTCGGTGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATA
GGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGC
ATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGT
GGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCAC
ACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAG
TTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAAT
ATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAAT
CTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGAT
CAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTG
GTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATG
CCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTG
TGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGAGACTTAATGGAGCATTTAGTTCCCCATCCTG
AATTCAAGATGCTGAGTGTTCGTAACATTCCTCACATGTCTGAGAATTCATTGGCATACACCACATTTACTTGGGCTGGCCTCCTCAAGC
ATTTGAGACAGATGCTCATTTCTAATGCAAAGATGGAAGAAGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGA
ACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTAT
TTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAA
ACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGA
TTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACT
CAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGT
TGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGC
ACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGA
ATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGA
GATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCC
AGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGA
CATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAA
CAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCCACAGGAGGAGGCAGCAGCATGTCCTCCTCACATTCTTCCACCAGAGAAGAG
GCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACCC
AGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACC
AATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATGA
ACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGGA
GTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGGT
GGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGCC
AGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGCC
TACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCCA
TCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTTG
TATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATTT
ACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGCA
CTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGATT
GTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCTC
TTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAAG
TGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAGA
TACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTTG
CTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGT
TTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAAA
GGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATTT
GTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATAT
TGTTTACACATATATTTTTATGTCAAAAAAAAAACAAAAACCTTTCAAACAGAGCATTGTGATATTGTCAAAGAGAAAAACAAATCCTGA
AGATACATGGAAATGTAACCTAGTTTAGGGTGGGTATTTTTCTGAAGATACATCAATACCTGACCTTTTTTAAAAAAATAATTTTAAAAC
AGCATACTGTGAGGAAGAACAGTATTGACATACCCACATCCCAGCATGTGTACCCTGCCAGTTCTTTTAGGGATTTTTCCTCCAAAGAGA
TTTGGATTTGGTTTTGGTAAAAGGGGTTAAATTGTGCTTCCAGGCAAGAACTTTGCCTTATCATAAACAGGAAATGAAAAAGGGAAGGGC
TGTCAGGATGGGATAATTTGGGAGGCTTCTCATTCTGGCTTCTATTTCTATGTGAGTACCAGCATATAGAGTGTTTTAAAAACAGATACA
TGTCATATAATTTATCTGCACAGACTTAGACCTTCAGGAAACATAGGTTAAGCCCCCTTTTACAAAGAAAAAGTAAACATACTTCAGCAT
CTTGGAGGGTAGTTTTCAAAACTCAAGTTTCATGTTTCAATGCCAAGTTCTTATTTTAAAAAATAAAATCTACTTATAAGAGAAAGGTGC
ATTACTTAAAAAAAAAAAACTTTAAAGAAATGAAAGAAGAACCCTCTTCAGATACTTACTTGAAGACTGTTTTCCCCTGTTAATGAGATA
TAGCTAGATATCGGTGTGTGTATTTCTTTATTATTCTCTGGTTTTTGATCTGGCCTTGCCTCCAGGGCCAAACACTGATTTAGAAAGAGA
GCCTTCTAGCTATTTTGGCATTGATGGCTTTTTATACCAGTGTGTCCAGTTAGATTTACTAGGCTTACTGACATGCTATTGGTAAATCGC
ATTAAAGTTCATCTGAACCTTCTGTCTGTTGACTTCTTAGTCCTCAGACATGGGCCTTTGTGTTTTAGAATATTTGAATTTGAGTTATTG
GGCCCCACTCCCTGTTTTTTATTAAAGAACGTGAGCCTGGGATACTTTCAGAAGTATCTGTTCAATGAAAAAAAGTTGGTTTCCCATCAA
ATATGAATAAAATTCTCTATATATTTCATTGTATTTTGGTTATCAGCAGTCATCAATAATGTTTTTCCCTCCCCTCTCCCACCTCTTATT
TTTAATTATGCCAAATATCCTAAATAATATACTTAAGCCTCCATTCCCTCATCCCTACTAGGGAAGGGGGTGAGTGTATGTGTGAGTGTA
TGTGTATGTATGATCCCATCTCACCCCCACCCCCATTTTGGGAGTCTTTTAAAATGAAAACAAAGTTTGGTAGTTTTGACTATTTCTAAA
AGCAGAGGAGAAAAAAAAACTTATTTAAATATCCTGGAATCTGTATGGAGGAAGAAAAGGTATTTGTTAATTTTTCAGTTACGTTATCTA
TAAACATGATGGAAGTAAAGGTTTGGCAGAATTTCACCTTGACTATTTGAAAATTACAGACCCAATTAATTCCATTCAAAAGTGGTTTTC
GTTTTGTTTTAATTATTGTACAATGAGAGATATTGTCTATTAAATACATTATTTTGAACAGATGAGAAATCTGATTCTGTTCATGAGTGG
GAGGCAAAACTGGTTTGACCGTGATCATTTTTGTGGTTTTGAAAACAAATATACTTGACCCAGTTTCCTTAGTTTTTTCTTCAACTGTCC
ATAGGAACGATAAGTATTTGAAAGCAACATCAAATCTATACGTTTAAAGCAGGGCAGTTAGCACAAATTTGCAAGTAGAACTTCTATTAG
CTTATGCCATAGACATCACCCAACCACTTGTATGTGTGTGTGTATATATAATATGCATATATAGTTACCGTGCTAAAATGGTTACCAGCA
GGTTTTGAGAGAGAATGCTGCATCAGAAAAGTGTCAGTTGCCACCTCATTCTCCCTGATTTAGGTTCCTGACACTGATTCCTTTCTCTCT
CGTTTTTGACCCCCATTGGGTGTATCTTGTCTATGTACAGATATTTTGTAATATATTAAATTTTTTTCTTTCAGTTTATAAAAATGGAAA
GTGGAGATTGGAAAATTAAATATTTCCTGTTACTATACCACTTTTGCTCCATTGCATTTACTTCTTAATCTGTACCCCCTGAGCATATCT
AATCATGTATAAAGGACGTTTTTCCTCCACTTTATCTTAGGGGTTCTCTGTCTCAGAATCATTATAGACTCATTAACTCCCCCTCCCAGC
AAAAGGTTATCAGGATTTGAAGAGGTGCTTGAAAACGCTAGACTAGGAACTAGAGAATAAATGAGTTGGGAAAAACCATGAAATGTGATT
TTTTTAAAGTAGAAAAGTTATACAAATAATGGTACCAAACCATCAAAAGAGTTGAGCTTCATGTACCCTGACTCCTCCTGACAGGAGAGG
TAAGTGGGTTTGAGCTCAACTGTCATCAAGGGAAGTTGGTAAGAGGCTGTTTAGACCCAAAGGATAGTCTTAAACCAGACTTCACCACCC
ACCCTACCTCAGTTCCCATGTTATTACATGCAGAGTCAGCATGGGGATTAGTGTACCTACCTTTGCTGAGATTTCCCGATGCGTTGCCAA
TCCAGAAAGTGAATCAAAAAGTTGTTTAAAAGTTAAAATCTCTATTGTTTCCAAAATCTTTCCCATCTCCACCTGAAGACAGAATTGCTT

>95378_95378_18_TUBD1-CDK12_TUBD1_chr17_57951900_ENST00000325752_CDK12_chr17_37667782_ENST00000447079_length(amino acids)=592AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPH
ILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGF
SAIDTDERNSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQ

--------------------------------------------------------------
>95378_95378_19_TUBD1-CDK12_TUBD1_chr17_57951900_ENST00000394239_CDK12_chr17_37667782_ENST00000430627_length(transcript)=4076nt_BP=1135nt
ATCTTTCTGAATAGGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAA
AGTGAGCATGCGCATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAAT
ACACCTAGTTTGTGGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTG
CTTAGTGACTCACACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAG
GAGGAGAATGGAGTTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCT
GGCCAATGGAAATATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCC
AGGCATGAAGAATCTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCT
GGGGGCACAGGATCAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGG
CCTTATGGAACTGGTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTT
CATGAGAATGATGCCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACAT
CAGCTGGGAAGTGTGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGAGACTTAATGGAGCATTTA
GTTCCCCATCCTGAATTCAAGATGCTGAGTGTTCGTAACATTCCTCACATGTCTGAGAATTCATTGGCATACACCACATTTACTTGGGCT
GGCCTCCTCAAGCATTTGAGACAGATGCTCATTTCTAATGCAAAGATGGAAGAAGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGT
ACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCA
CAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGC
CTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTT
CTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTA
AAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGC
GACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGA
ACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACAGC
TGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCC
ACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAG
AGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAA
GCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACA
ACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCCACAGGAGGAGGCAGCAGAGAAGAGGCCCCCTGAGCCCC
CCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCG
CCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCA
CCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTC
CAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACC
AGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCAT
TCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGG
CCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCAC
CAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGT
TCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCAC
TTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATTTACTTCAACTCTACC
TTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAA
GAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTT
TCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTA
TAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCC
CCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCC
TGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCT
CTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGA
GGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTC
TTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAG
CTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATATTGTTTACACATATA

>95378_95378_19_TUBD1-CDK12_TUBD1_chr17_57951900_ENST00000394239_CDK12_chr17_37667782_ENST00000430627_length(amino acids)=583AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPP
EPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERN
SGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGT

--------------------------------------------------------------
>95378_95378_20_TUBD1-CDK12_TUBD1_chr17_57951900_ENST00000394239_CDK12_chr17_37667782_ENST00000447079_length(transcript)=6772nt_BP=1135nt
ATCTTTCTGAATAGGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAA
AGTGAGCATGCGCATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAAT
ACACCTAGTTTGTGGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTG
CTTAGTGACTCACACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAG
GAGGAGAATGGAGTTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCT
GGCCAATGGAAATATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCC
AGGCATGAAGAATCTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCT
GGGGGCACAGGATCAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGG
CCTTATGGAACTGGTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTT
CATGAGAATGATGCCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACAT
CAGCTGGGAAGTGTGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGGAGACTTAATGGAGCATTTA
GTTCCCCATCCTGAATTCAAGATGCTGAGTGTTCGTAACATTCCTCACATGTCTGAGAATTCATTGGCATACACCACATTTACTTGGGCT
GGCCTCCTCAAGCATTTGAGACAGATGCTCATTTCTAATGCAAAGATGGAAGAAGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGT
ACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCA
CAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGC
CTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTT
CTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTA
AAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGC
GACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGA
ACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACAGC
TGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCC
ACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAG
AGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAA
GCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACA
ACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCCACAGGAGGAGGCAGCAGCATGTCCTCCTCACATTCTTC
CACCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCC
AGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACC
AGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCA
TTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGA
GCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAG
CGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATG
GGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAAC
TCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATT
CCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCA
AAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTAT
AGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAG
TTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTT
GGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAA
ATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACA
TTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCA
CTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCT
CTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGC
TCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTT
GAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATG
GGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACA
GCATTTAGCATATTGTTTACACATATATTTTTATGTCAAAAAAAAAACAAAAACCTTTCAAACAGAGCATTGTGATATTGTCAAAGAGAA
AAACAAATCCTGAAGATACATGGAAATGTAACCTAGTTTAGGGTGGGTATTTTTCTGAAGATACATCAATACCTGACCTTTTTTAAAAAA
ATAATTTTAAAACAGCATACTGTGAGGAAGAACAGTATTGACATACCCACATCCCAGCATGTGTACCCTGCCAGTTCTTTTAGGGATTTT
TCCTCCAAAGAGATTTGGATTTGGTTTTGGTAAAAGGGGTTAAATTGTGCTTCCAGGCAAGAACTTTGCCTTATCATAAACAGGAAATGA
AAAAGGGAAGGGCTGTCAGGATGGGATAATTTGGGAGGCTTCTCATTCTGGCTTCTATTTCTATGTGAGTACCAGCATATAGAGTGTTTT
AAAAACAGATACATGTCATATAATTTATCTGCACAGACTTAGACCTTCAGGAAACATAGGTTAAGCCCCCTTTTACAAAGAAAAAGTAAA
CATACTTCAGCATCTTGGAGGGTAGTTTTCAAAACTCAAGTTTCATGTTTCAATGCCAAGTTCTTATTTTAAAAAATAAAATCTACTTAT
AAGAGAAAGGTGCATTACTTAAAAAAAAAAAACTTTAAAGAAATGAAAGAAGAACCCTCTTCAGATACTTACTTGAAGACTGTTTTCCCC
TGTTAATGAGATATAGCTAGATATCGGTGTGTGTATTTCTTTATTATTCTCTGGTTTTTGATCTGGCCTTGCCTCCAGGGCCAAACACTG
ATTTAGAAAGAGAGCCTTCTAGCTATTTTGGCATTGATGGCTTTTTATACCAGTGTGTCCAGTTAGATTTACTAGGCTTACTGACATGCT
ATTGGTAAATCGCATTAAAGTTCATCTGAACCTTCTGTCTGTTGACTTCTTAGTCCTCAGACATGGGCCTTTGTGTTTTAGAATATTTGA
ATTTGAGTTATTGGGCCCCACTCCCTGTTTTTTATTAAAGAACGTGAGCCTGGGATACTTTCAGAAGTATCTGTTCAATGAAAAAAAGTT
GGTTTCCCATCAAATATGAATAAAATTCTCTATATATTTCATTGTATTTTGGTTATCAGCAGTCATCAATAATGTTTTTCCCTCCCCTCT
CCCACCTCTTATTTTTAATTATGCCAAATATCCTAAATAATATACTTAAGCCTCCATTCCCTCATCCCTACTAGGGAAGGGGGTGAGTGT
ATGTGTGAGTGTATGTGTATGTATGATCCCATCTCACCCCCACCCCCATTTTGGGAGTCTTTTAAAATGAAAACAAAGTTTGGTAGTTTT
GACTATTTCTAAAAGCAGAGGAGAAAAAAAAACTTATTTAAATATCCTGGAATCTGTATGGAGGAAGAAAAGGTATTTGTTAATTTTTCA
GTTACGTTATCTATAAACATGATGGAAGTAAAGGTTTGGCAGAATTTCACCTTGACTATTTGAAAATTACAGACCCAATTAATTCCATTC
AAAAGTGGTTTTCGTTTTGTTTTAATTATTGTACAATGAGAGATATTGTCTATTAAATACATTATTTTGAACAGATGAGAAATCTGATTC
TGTTCATGAGTGGGAGGCAAAACTGGTTTGACCGTGATCATTTTTGTGGTTTTGAAAACAAATATACTTGACCCAGTTTCCTTAGTTTTT
TCTTCAACTGTCCATAGGAACGATAAGTATTTGAAAGCAACATCAAATCTATACGTTTAAAGCAGGGCAGTTAGCACAAATTTGCAAGTA
GAACTTCTATTAGCTTATGCCATAGACATCACCCAACCACTTGTATGTGTGTGTGTATATATAATATGCATATATAGTTACCGTGCTAAA
ATGGTTACCAGCAGGTTTTGAGAGAGAATGCTGCATCAGAAAAGTGTCAGTTGCCACCTCATTCTCCCTGATTTAGGTTCCTGACACTGA
TTCCTTTCTCTCTCGTTTTTGACCCCCATTGGGTGTATCTTGTCTATGTACAGATATTTTGTAATATATTAAATTTTTTTCTTTCAGTTT
ATAAAAATGGAAAGTGGAGATTGGAAAATTAAATATTTCCTGTTACTATACCACTTTTGCTCCATTGCATTTACTTCTTAATCTGTACCC
CCTGAGCATATCTAATCATGTATAAAGGACGTTTTTCCTCCACTTTATCTTAGGGGTTCTCTGTCTCAGAATCATTATAGACTCATTAAC
TCCCCCTCCCAGCAAAAGGTTATCAGGATTTGAAGAGGTGCTTGAAAACGCTAGACTAGGAACTAGAGAATAAATGAGTTGGGAAAAACC
ATGAAATGTGATTTTTTTAAAGTAGAAAAGTTATACAAATAATGGTACCAAACCATCAAAAGAGTTGAGCTTCATGTACCCTGACTCCTC
CTGACAGGAGAGGTAAGTGGGTTTGAGCTCAACTGTCATCAAGGGAAGTTGGTAAGAGGCTGTTTAGACCCAAAGGATAGTCTTAAACCA
GACTTCACCACCCACCCTACCTCAGTTCCCATGTTATTACATGCAGAGTCAGCATGGGGATTAGTGTACCTACCTTTGCTGAGATTTCCC
GATGCGTTGCCAATCCAGAAAGTGAATCAAAAAGTTGTTTAAAAGTTAAAATCTCTATTGTTTCCAAAATCTTTCCCATCTCCACCTGAA

>95378_95378_20_TUBD1-CDK12_TUBD1_chr17_57951900_ENST00000394239_CDK12_chr17_37667782_ENST00000447079_length(amino acids)=592AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPH
ILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGF
SAIDTDERNSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQ

--------------------------------------------------------------
>95378_95378_21_TUBD1-CDK12_TUBD1_chr17_57955464_ENST00000325752_CDK12_chr17_37667782_ENST00000430627_length(transcript)=3988nt_BP=1047nt
AGCTGGAGCGTTCGGTGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATA
GGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGC
ATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGT
GGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCAC
ACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAG
TTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAAT
ATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAAT
CTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGAT
CAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTG
GTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATG
CCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTG
TGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGTCGCCCTTACACAAACAAAGTCATTACTTTGTG
GTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATT
CACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTG
GCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCC
TTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCT
TAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCA
GCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAA
GAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACA
GCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACAT
CCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTC
AGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTC
AAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAA
CAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCCACAGGAGGAGGCAGCAGAGAAGAGGCCCCCTGAGCC
CCCCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGC
CGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACCAATGGAGTACTC
CACCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATGAACGAAACTCTGG
TCCAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTA
CCAGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACC
ATTCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGG
GGCCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCC
ACCAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCA
GTTCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTC
ACTTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATTTACTTCAACTCTA
CCTTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGCACTTACTGATCGG
AAGAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTC
TTTCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGC
TATAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAAGTGAACACTTTTT
CCCCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAGATACGCCCTTCTC
CCTGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCT
CTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTT
GAGGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGAC
TCTTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGAC
AGCTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATATTGTTTACACATA

>95378_95378_21_TUBD1-CDK12_TUBD1_chr17_57955464_ENST00000325752_CDK12_chr17_37667782_ENST00000430627_length(amino acids)=583AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPP
EPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERN
SGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGT

--------------------------------------------------------------
>95378_95378_22_TUBD1-CDK12_TUBD1_chr17_57955464_ENST00000325752_CDK12_chr17_37667782_ENST00000447079_length(transcript)=6684nt_BP=1047nt
AGCTGGAGCGTTCGGTGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATA
GGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGC
ATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGT
GGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCAC
ACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAG
TTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAAT
ATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAAT
CTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGAT
CAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTG
GTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATG
CCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTG
TGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGTCGCCCTTACACAAACAAAGTCATTACTTTGTG
GTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATT
CACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTG
GCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCC
TTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCT
TAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCA
GCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAA
GAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACA
GCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACAT
CCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTC
AGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTC
AAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAA
CAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCCACAGGAGGAGGCAGCAGCATGTCCTCCTCACATTCT
TCCACCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCC
CCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCA
CCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGC
CATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCT
GAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTT
AGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATTGCAAAACTA
TGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAA
ACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGA
TTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTG
CAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCT
ATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAATGTTTTATT
AGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTT
TTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACA
AAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCA
CATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAAAGTTTACTC
CACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGT
CTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTT
GCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCTTTACTTTTT
TTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGA
TGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAA
CAGCATTTAGCATATTGTTTACACATATATTTTTATGTCAAAAAAAAAACAAAAACCTTTCAAACAGAGCATTGTGATATTGTCAAAGAG
AAAAACAAATCCTGAAGATACATGGAAATGTAACCTAGTTTAGGGTGGGTATTTTTCTGAAGATACATCAATACCTGACCTTTTTTAAAA
AAATAATTTTAAAACAGCATACTGTGAGGAAGAACAGTATTGACATACCCACATCCCAGCATGTGTACCCTGCCAGTTCTTTTAGGGATT
TTTCCTCCAAAGAGATTTGGATTTGGTTTTGGTAAAAGGGGTTAAATTGTGCTTCCAGGCAAGAACTTTGCCTTATCATAAACAGGAAAT
GAAAAAGGGAAGGGCTGTCAGGATGGGATAATTTGGGAGGCTTCTCATTCTGGCTTCTATTTCTATGTGAGTACCAGCATATAGAGTGTT
TTAAAAACAGATACATGTCATATAATTTATCTGCACAGACTTAGACCTTCAGGAAACATAGGTTAAGCCCCCTTTTACAAAGAAAAAGTA
AACATACTTCAGCATCTTGGAGGGTAGTTTTCAAAACTCAAGTTTCATGTTTCAATGCCAAGTTCTTATTTTAAAAAATAAAATCTACTT
ATAAGAGAAAGGTGCATTACTTAAAAAAAAAAAACTTTAAAGAAATGAAAGAAGAACCCTCTTCAGATACTTACTTGAAGACTGTTTTCC
CCTGTTAATGAGATATAGCTAGATATCGGTGTGTGTATTTCTTTATTATTCTCTGGTTTTTGATCTGGCCTTGCCTCCAGGGCCAAACAC
TGATTTAGAAAGAGAGCCTTCTAGCTATTTTGGCATTGATGGCTTTTTATACCAGTGTGTCCAGTTAGATTTACTAGGCTTACTGACATG
CTATTGGTAAATCGCATTAAAGTTCATCTGAACCTTCTGTCTGTTGACTTCTTAGTCCTCAGACATGGGCCTTTGTGTTTTAGAATATTT
GAATTTGAGTTATTGGGCCCCACTCCCTGTTTTTTATTAAAGAACGTGAGCCTGGGATACTTTCAGAAGTATCTGTTCAATGAAAAAAAG
TTGGTTTCCCATCAAATATGAATAAAATTCTCTATATATTTCATTGTATTTTGGTTATCAGCAGTCATCAATAATGTTTTTCCCTCCCCT
CTCCCACCTCTTATTTTTAATTATGCCAAATATCCTAAATAATATACTTAAGCCTCCATTCCCTCATCCCTACTAGGGAAGGGGGTGAGT
GTATGTGTGAGTGTATGTGTATGTATGATCCCATCTCACCCCCACCCCCATTTTGGGAGTCTTTTAAAATGAAAACAAAGTTTGGTAGTT
TTGACTATTTCTAAAAGCAGAGGAGAAAAAAAAACTTATTTAAATATCCTGGAATCTGTATGGAGGAAGAAAAGGTATTTGTTAATTTTT
CAGTTACGTTATCTATAAACATGATGGAAGTAAAGGTTTGGCAGAATTTCACCTTGACTATTTGAAAATTACAGACCCAATTAATTCCAT
TCAAAAGTGGTTTTCGTTTTGTTTTAATTATTGTACAATGAGAGATATTGTCTATTAAATACATTATTTTGAACAGATGAGAAATCTGAT
TCTGTTCATGAGTGGGAGGCAAAACTGGTTTGACCGTGATCATTTTTGTGGTTTTGAAAACAAATATACTTGACCCAGTTTCCTTAGTTT
TTTCTTCAACTGTCCATAGGAACGATAAGTATTTGAAAGCAACATCAAATCTATACGTTTAAAGCAGGGCAGTTAGCACAAATTTGCAAG
TAGAACTTCTATTAGCTTATGCCATAGACATCACCCAACCACTTGTATGTGTGTGTGTATATATAATATGCATATATAGTTACCGTGCTA
AAATGGTTACCAGCAGGTTTTGAGAGAGAATGCTGCATCAGAAAAGTGTCAGTTGCCACCTCATTCTCCCTGATTTAGGTTCCTGACACT
GATTCCTTTCTCTCTCGTTTTTGACCCCCATTGGGTGTATCTTGTCTATGTACAGATATTTTGTAATATATTAAATTTTTTTCTTTCAGT
TTATAAAAATGGAAAGTGGAGATTGGAAAATTAAATATTTCCTGTTACTATACCACTTTTGCTCCATTGCATTTACTTCTTAATCTGTAC
CCCCTGAGCATATCTAATCATGTATAAAGGACGTTTTTCCTCCACTTTATCTTAGGGGTTCTCTGTCTCAGAATCATTATAGACTCATTA
ACTCCCCCTCCCAGCAAAAGGTTATCAGGATTTGAAGAGGTGCTTGAAAACGCTAGACTAGGAACTAGAGAATAAATGAGTTGGGAAAAA
CCATGAAATGTGATTTTTTTAAAGTAGAAAAGTTATACAAATAATGGTACCAAACCATCAAAAGAGTTGAGCTTCATGTACCCTGACTCC
TCCTGACAGGAGAGGTAAGTGGGTTTGAGCTCAACTGTCATCAAGGGAAGTTGGTAAGAGGCTGTTTAGACCCAAAGGATAGTCTTAAAC
CAGACTTCACCACCCACCCTACCTCAGTTCCCATGTTATTACATGCAGAGTCAGCATGGGGATTAGTGTACCTACCTTTGCTGAGATTTC
CCGATGCGTTGCCAATCCAGAAAGTGAATCAAAAAGTTGTTTAAAAGTTAAAATCTCTATTGTTTCCAAAATCTTTCCCATCTCCACCTG

>95378_95378_22_TUBD1-CDK12_TUBD1_chr17_57955464_ENST00000325752_CDK12_chr17_37667782_ENST00000447079_length(amino acids)=592AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPH
ILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGF
SAIDTDERNSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQ

--------------------------------------------------------------
>95378_95378_23_TUBD1-CDK12_TUBD1_chr17_57955464_ENST00000340993_CDK12_chr17_37667782_ENST00000430627_length(transcript)=3973nt_BP=1032nt
TGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATAGGAAAAAATATATAC
ACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGCATGGTGAGTAGGTTG
GTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGTGGCTCAGCATGTCAA
TTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCACACAGTTCCCAGGGAC
TCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAGTTCCAATTGCCCGGG
CTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAATATGGTCAACATGCAT
GCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAATCTATAATGAACATAA
TCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGATCAGGATTAGGAGCTT
TCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTGGTGAGGTTATTGTTC
AAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATGCCATCCATAAGATCT
GTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTGTGTTCCAGCCTACTT
ATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGA
ACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTAT
TTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAA
ACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGA
TTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACT
CAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGT
TGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGC
ACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGA
ATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGA
GATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCC
AGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGA
CATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAA
CAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCCACAGGAGGAGGCAGCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACC
GCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACT
TTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCC
AAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGA
ATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTC
AGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGA
GGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGG
AGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAG
AGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTT
AATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAG
GCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAA
GTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACA
GTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTT
AATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGA
GTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCT
TGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCA
GGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTC
TCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGG
AAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTC
TGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCT
GCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATATTGTTTACACATATATTTTTATGTCAAA

>95378_95378_23_TUBD1-CDK12_TUBD1_chr17_57955464_ENST00000340993_CDK12_chr17_37667782_ENST00000430627_length(amino acids)=583AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPP
EPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERN
SGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGT

--------------------------------------------------------------
>95378_95378_24_TUBD1-CDK12_TUBD1_chr17_57955464_ENST00000340993_CDK12_chr17_37667782_ENST00000447079_length(transcript)=6669nt_BP=1032nt
TGGACAGTGAGCATGCGTACCATATCTGAAGTTCGTAAATTGAAATTGAACATGCGTAATTAATCTTTCTGAATAGGAAAAAATATATAC
ACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAAAGTGAGCATGCGCATGGTGAGTAGGTTG
GTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAATACACCTAGTTTGTGGCTCAGCATGTCAA
TTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTGCTTAGTGACTCACACAGTTCCCAGGGAC
TCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAGGAGGAGAATGGAGTTCCAATTGCCCGGG
CTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCTGGCCAATGGAAATATGGTCAACATGCAT
GCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCCAGGCATGAAGAATCTATAATGAACATAA
TCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCTGGGGGCACAGGATCAGGATTAGGAGCTT
TCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGGCCTTATGGAACTGGTGAGGTTATTGTTC
AAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTTCATGAGAATGATGCCATCCATAAGATCT
GTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACATCAGCTGGGAAGTGTGTTCCAGCCTACTT
ATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGTCGCCCTTACACAAACAAAGTCATTACTTTGTGGTACCGACCTCCAGA
ACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGATGTTTGGAGCTGTGGATGTATTCTTGGGGAACTATTCACAAAGAAGCCTAT
TTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGATCAGCCGACTTTGTGGTAGCCCTTGTCCAGCTGTGTGGCCTGATGTTATCAA
ACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATATCGAAGGCGTCTACGAGAAGAATTCTCTTTCATTCCTTCTGCAGCACTTGA
TTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCGGTGCACAGCTGAACAGACCCTACAGAGCGACTTCCTTAAAGATGTCGAACT
CAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGATTGCCATGAGTTGTGGAGTAAGAAACGGCGACGTCAGCGACAAAGTGGTGT
TGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAAAGAAACTACCTCAGGGACAAGTACTGAGCCTGTGAAGAACAGCAGCCCAGC
ACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGCTGGGGATGCAATAGGCCTTGCTGACATCACACAACAGCTGAATCAAAGTGA
ATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGACCTGAGCATCCCTCAAATGGCACAGCTGCTTAACATCCACTCCAACCCAGA
GATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAGTGCCCTGACGGAAGCTACTTCCCAGCAGCAGGACTCAGAGACCATGGCCCC
AGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGATCCTGCCTTCAGCAGAACAGACGACCCTTGAAGCTTCAAGCACACCAGCTGA
CATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGATGAAAACCCAAGAGCCAGCAGGCAGTCTGGAGGAAAACAACAGTGACAAGAA
CAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCCACAGGAGGAGGCAGCAGCATGTCCTCCTCACATTCTTCCACCAGAGAAGAG
GCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACCC
AGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGACC
AATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATGA
ACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGGA
GTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGGT
GGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGCC
AGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGCC
TACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCCA
TCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTTG
TATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATTT
ACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGCA
CTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGATT
GTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCTC
TTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAAG
TGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAGA
TACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTTG
CTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTGT
TTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAAA
GGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATTT
GTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATAT
TGTTTACACATATATTTTTATGTCAAAAAAAAAACAAAAACCTTTCAAACAGAGCATTGTGATATTGTCAAAGAGAAAAACAAATCCTGA
AGATACATGGAAATGTAACCTAGTTTAGGGTGGGTATTTTTCTGAAGATACATCAATACCTGACCTTTTTTAAAAAAATAATTTTAAAAC
AGCATACTGTGAGGAAGAACAGTATTGACATACCCACATCCCAGCATGTGTACCCTGCCAGTTCTTTTAGGGATTTTTCCTCCAAAGAGA
TTTGGATTTGGTTTTGGTAAAAGGGGTTAAATTGTGCTTCCAGGCAAGAACTTTGCCTTATCATAAACAGGAAATGAAAAAGGGAAGGGC
TGTCAGGATGGGATAATTTGGGAGGCTTCTCATTCTGGCTTCTATTTCTATGTGAGTACCAGCATATAGAGTGTTTTAAAAACAGATACA
TGTCATATAATTTATCTGCACAGACTTAGACCTTCAGGAAACATAGGTTAAGCCCCCTTTTACAAAGAAAAAGTAAACATACTTCAGCAT
CTTGGAGGGTAGTTTTCAAAACTCAAGTTTCATGTTTCAATGCCAAGTTCTTATTTTAAAAAATAAAATCTACTTATAAGAGAAAGGTGC
ATTACTTAAAAAAAAAAAACTTTAAAGAAATGAAAGAAGAACCCTCTTCAGATACTTACTTGAAGACTGTTTTCCCCTGTTAATGAGATA
TAGCTAGATATCGGTGTGTGTATTTCTTTATTATTCTCTGGTTTTTGATCTGGCCTTGCCTCCAGGGCCAAACACTGATTTAGAAAGAGA
GCCTTCTAGCTATTTTGGCATTGATGGCTTTTTATACCAGTGTGTCCAGTTAGATTTACTAGGCTTACTGACATGCTATTGGTAAATCGC
ATTAAAGTTCATCTGAACCTTCTGTCTGTTGACTTCTTAGTCCTCAGACATGGGCCTTTGTGTTTTAGAATATTTGAATTTGAGTTATTG
GGCCCCACTCCCTGTTTTTTATTAAAGAACGTGAGCCTGGGATACTTTCAGAAGTATCTGTTCAATGAAAAAAAGTTGGTTTCCCATCAA
ATATGAATAAAATTCTCTATATATTTCATTGTATTTTGGTTATCAGCAGTCATCAATAATGTTTTTCCCTCCCCTCTCCCACCTCTTATT
TTTAATTATGCCAAATATCCTAAATAATATACTTAAGCCTCCATTCCCTCATCCCTACTAGGGAAGGGGGTGAGTGTATGTGTGAGTGTA
TGTGTATGTATGATCCCATCTCACCCCCACCCCCATTTTGGGAGTCTTTTAAAATGAAAACAAAGTTTGGTAGTTTTGACTATTTCTAAA
AGCAGAGGAGAAAAAAAAACTTATTTAAATATCCTGGAATCTGTATGGAGGAAGAAAAGGTATTTGTTAATTTTTCAGTTACGTTATCTA
TAAACATGATGGAAGTAAAGGTTTGGCAGAATTTCACCTTGACTATTTGAAAATTACAGACCCAATTAATTCCATTCAAAAGTGGTTTTC
GTTTTGTTTTAATTATTGTACAATGAGAGATATTGTCTATTAAATACATTATTTTGAACAGATGAGAAATCTGATTCTGTTCATGAGTGG
GAGGCAAAACTGGTTTGACCGTGATCATTTTTGTGGTTTTGAAAACAAATATACTTGACCCAGTTTCCTTAGTTTTTTCTTCAACTGTCC
ATAGGAACGATAAGTATTTGAAAGCAACATCAAATCTATACGTTTAAAGCAGGGCAGTTAGCACAAATTTGCAAGTAGAACTTCTATTAG
CTTATGCCATAGACATCACCCAACCACTTGTATGTGTGTGTGTATATATAATATGCATATATAGTTACCGTGCTAAAATGGTTACCAGCA
GGTTTTGAGAGAGAATGCTGCATCAGAAAAGTGTCAGTTGCCACCTCATTCTCCCTGATTTAGGTTCCTGACACTGATTCCTTTCTCTCT
CGTTTTTGACCCCCATTGGGTGTATCTTGTCTATGTACAGATATTTTGTAATATATTAAATTTTTTTCTTTCAGTTTATAAAAATGGAAA
GTGGAGATTGGAAAATTAAATATTTCCTGTTACTATACCACTTTTGCTCCATTGCATTTACTTCTTAATCTGTACCCCCTGAGCATATCT
AATCATGTATAAAGGACGTTTTTCCTCCACTTTATCTTAGGGGTTCTCTGTCTCAGAATCATTATAGACTCATTAACTCCCCCTCCCAGC
AAAAGGTTATCAGGATTTGAAGAGGTGCTTGAAAACGCTAGACTAGGAACTAGAGAATAAATGAGTTGGGAAAAACCATGAAATGTGATT
TTTTTAAAGTAGAAAAGTTATACAAATAATGGTACCAAACCATCAAAAGAGTTGAGCTTCATGTACCCTGACTCCTCCTGACAGGAGAGG
TAAGTGGGTTTGAGCTCAACTGTCATCAAGGGAAGTTGGTAAGAGGCTGTTTAGACCCAAAGGATAGTCTTAAACCAGACTTCACCACCC
ACCCTACCTCAGTTCCCATGTTATTACATGCAGAGTCAGCATGGGGATTAGTGTACCTACCTTTGCTGAGATTTCCCGATGCGTTGCCAA
TCCAGAAAGTGAATCAAAAAGTTGTTTAAAAGTTAAAATCTCTATTGTTTCCAAAATCTTTCCCATCTCCACCTGAAGACAGAATTGCTT

>95378_95378_24_TUBD1-CDK12_TUBD1_chr17_57955464_ENST00000340993_CDK12_chr17_37667782_ENST00000447079_length(amino acids)=592AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPH
ILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGF
SAIDTDERNSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQ

--------------------------------------------------------------
>95378_95378_25_TUBD1-CDK12_TUBD1_chr17_57955464_ENST00000394239_CDK12_chr17_37667782_ENST00000430627_length(transcript)=3911nt_BP=970nt
ATCTTTCTGAATAGGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAA
AGTGAGCATGCGCATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAAT
ACACCTAGTTTGTGGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTG
CTTAGTGACTCACACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAG
GAGGAGAATGGAGTTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCT
GGCCAATGGAAATATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCC
AGGCATGAAGAATCTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCT
GGGGGCACAGGATCAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGG
CCTTATGGAACTGGTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTT
CATGAGAATGATGCCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACAT
CAGCTGGGAAGTGTGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGTCGCCCTTACACAAACAAAG
TCATTACTTTGTGGTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGATGTTTGGAGCTGTGGATGTATTC
TTGGGGAACTATTCACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGATCAGCCGACTTTGTGGTAGCCCTT
GTCCAGCTGTGTGGCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATATCGAAGGCGTCTACGAGAAGAAT
TCTCTTTCATTCCTTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCGGTGCACAGCTGAACAGACCCTAC
AGAGCGACTTCCTTAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGATTGCCATGAGTTGTGGAGTAAGA
AACGGCGACGTCAGCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAAAGAAACTACCTCAGGGACAAGTA
CTGAGCCTGTGAAGAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGCTGGGGATGCAATAGGCCTTGCTG
ACATCACACAACAGCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGACCTGAGCATCCCTCAAATGGCAC
AGCTGCTTAACATCCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAGTGCCCTGACGGAAGCTACTTCCC
AGCAGCAGGACTCAGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGATCCTGCCTTCAGCAGAACAGACGA
CCCTTGAAGCTTCAAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGATGAAAACCCAAGAGCCAGCAGGCA
GTCTGGAGGAAAACAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCCACAGGAGGAGGCAGCAGAGAAGA
GGCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAACC
CAGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCACCAGGCCTTGAGAC
CAATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCTGAAACAGGGTTCAGTGCCATTGACACTGATG
AACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCTTCTCAGGCTCTCTGAGCCACCTTGGGG
AGTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTGCCAGGGTCCCCTTAGCGTTACACCCGG
TGGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAGACCAAATTGCAAAACTATGGGGAGCTGGGGC
CAGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTTCTGCTTATGGAAAACTCTATCGGGGGC
CTACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCAGTGTCCTGAAAGATTCCTTTCCTATCC
ATCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCATCTGCATTTGGCTACTGCAAAGCTGTCCGTT
GTATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAGTTCCCCCTGGATGGGCTATAGCCAGAACATT
TACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGAAAAGTAAATGTTTTATTAGTTCATTGCCTGC
ACTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTTGATTTTTAAAGTTTTGGGGTGGGGGAT
TGTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAGAATAGTGTTCACAAAATTTGAGCTGCT
CTTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCTCTCCACCATCTCACATTTTGCTTTTAA
GTGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTCATCCTTAAAGTTTACTCCACTTTGACAAAAG
ATACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTAGACTTTACCCAGTCTCTTTCCTTTTTT
GCTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCGCTTGCTCGCTCTCGCTG
TTTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGGATAATTCTTTACTTTTTTTGAAATAAAGGAA
AGGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTAAACCATGTTCTGATGGGGAAGTTGATT
TGTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCTAGAGGGCTAATAACAGCATTTAGCATA

>95378_95378_25_TUBD1-CDK12_TUBD1_chr17_57955464_ENST00000394239_CDK12_chr17_37667782_ENST00000430627_length(amino acids)=583AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPP
EPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERN
SGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGT

--------------------------------------------------------------
>95378_95378_26_TUBD1-CDK12_TUBD1_chr17_57955464_ENST00000394239_CDK12_chr17_37667782_ENST00000447079_length(transcript)=6607nt_BP=970nt
ATCTTTCTGAATAGGAAAAAATATATACACAACAAAACTCTCCGTTTATGGAACATGCGCATTTGTTCTCAGTAAGTTTTTCGTTTTGAA
AGTGAGCATGCGCATGGTGAGTAGGTTGGTCCGAAGTTTGAACCGGACAGAAGCGCTGGTCGGCGTCTGGCGGTTGTTTTTAGAGGTAAT
ACACCTAGTTTGTGGCTCAGCATGTCAATTGTAACAGTGCAACTTGGTCAGTGTGGCAATCAGATTGGTTTTGAAGTTTTTGATGCTTTG
CTTAGTGACTCACACAGTTCCCAGGGACTCTGCTCTATGAGAGAGAATGAGGCATATCAAGCATCTTGCAAAGAAAGATTCTTCAGTGAG
GAGGAGAATGGAGTTCCAATTGCCCGGGCTGTTCTTGTTGACATGGAACCCAAAGTTATCAATCAAATGCTGTCAAAGGCTGCCCAGTCT
GGCCAATGGAAATATGGTCAACATGCATGCTTCTGTCAAAAACAAGGTTCTGGAAACAACTGGGCATATGGTTACTCTGTTCATGGACCC
AGGCATGAAGAATCTATAATGAACATAATCCGGAAGGAAGTGGAGAAATGTGACTCTTTCAGTGGTTTTTTCATCATAATGAGTATGGCT
GGGGGCACAGGATCAGGATTAGGAGCTTTCGTTACACAGAATTTAGAAGATCAGTACTCAAACTCATTGAAAATGAATCAGATTATTTGG
CCTTATGGAACTGGTGAGGTTATTGTTCAAAACTACAACTCCATTTTGACACTTTCTCACTTGTACCGATCTTCAGACGCCCTCCTTCTT
CATGAGAATGATGCCATCCATAAGATCTGTGCAAAACTGATGAATATCAAGCAGATCTCCTTTAGTGATATCAATCAAGTCCTCGCACAT
CAGCTGGGAAGTGTGTTCCAGCCTACTTATTCTGCAGAAAGCTCATTTCACTACAGACGAAATCCACTAGTCGCCCTTACACAAACAAAG
TCATTACTTTGTGGTACCGACCTCCAGAACTACTGCTAGGAGAGGAACGTTACACACCAGCCATAGATGTTTGGAGCTGTGGATGTATTC
TTGGGGAACTATTCACAAAGAAGCCTATTTTTCAAGCCAATCTGGAACTGGCTCAGCTAGAACTGATCAGCCGACTTTGTGGTAGCCCTT
GTCCAGCTGTGTGGCCTGATGTTATCAAACTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATATCGAAGGCGTCTACGAGAAGAAT
TCTCTTTCATTCCTTCTGCAGCACTTGATTTATTGGACCACATGCTGACACTAGATCCTAGTAAGCGGTGCACAGCTGAACAGACCCTAC
AGAGCGACTTCCTTAAAGATGTCGAACTCAGCAAAATGGCTCCTCCAGACCTCCCCCACTGGCAGGATTGCCATGAGTTGTGGAGTAAGA
AACGGCGACGTCAGCGACAAAGTGGTGTTGTAGTCGAAGAGCCACCTCCATCCAAAACTTCTCGAAAAGAAACTACCTCAGGGACAAGTA
CTGAGCCTGTGAAGAACAGCAGCCCAGCACCACCTCAGCCTGCTCCTGGCAAGGTGGAGTCTGGGGCTGGGGATGCAATAGGCCTTGCTG
ACATCACACAACAGCTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTGCAGAGCCAAACCGACCTGAGCATCCCTCAAATGGCAC
AGCTGCTTAACATCCACTCCAACCCAGAGATGCAGCAGCAGCTGGAAGCCCTGAACCAATCCATCAGTGCCCTGACGGAAGCTACTTCCC
AGCAGCAGGACTCAGAGACCATGGCCCCAGAGGAGTCTTTGAAGGAAGCACCCTCTGCCCCAGTGATCCTGCCTTCAGCAGAACAGACGA
CCCTTGAAGCTTCAAGCACACCAGCTGACATGCAGAATATATTGGCAGTTCTCTTGAGTCAGCTGATGAAAACCCAAGAGCCAGCAGGCA
GTCTGGAGGAAAACAACAGTGACAAGAACAGTGGGCCACAGGGGCCCCGAAGAACTCCCACAATGCCACAGGAGGAGGCAGCAGCATGTC
CTCCTCACATTCTTCCACCAGAGAAGAGGCCCCCTGAGCCCCCCGGACCTCCACCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATC
TTTCCAGCGCCCCCCAGGAGTTGAACCCAGCCGTGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACC
TGCCACATGAGCACCAGGCCTTGAGACCAATGGAGTACTCCACCCGACCCCGTCCAAACAGGACTTATGGAAACACTGATGGGCCTGAAA
CAGGGTTCAGTGCCATTGACACTGATGAACGAAACTCTGGTCCAGCCTTGACAGAATCCTTGGTCCAGACCCTGGTGAAGAACAGGACCT
TCTCAGGCTCTCTGAGCCACCTTGGGGAGTCCAGCAGTTACCAGGGCACAGGGTCAGTGCAGTTTCCAGGGGACCAGGACCTCCGTTTTG
CCAGGGTCCCCTTAGCGTTACACCCGGTGGTCGGGCAACCATTCCTGAAGGCTGAGGGAAGCAGCAATTCTGTGGTACATGCAGAGACCA
AATTGCAAAACTATGGGGAGCTGGGGCCAGGAACCACTGGGGCCAGCAGCTCAGGAGCAGGCCTTCACTGGGGGGGCCCAACTCAGTCTT
CTGCTTATGGAAAACTCTATCGGGGGCCTACAAGAGTCCCACCAAGAGGGGGAAGAGGGAGAGGAGTTCCTTACTAACCCAGAGACTTCA
GTGTCCTGAAAGATTCCTTTCCTATCCATCCTTCCATCCAGTTCTCTGAATCTTTAATGAAATCATTTGCCAGAGCGAGGTAATCATCTG
CATTTGGCTACTGCAAAGCTGTCCGTTGTATTCCTTGCTCACTTGCTACTAGCAGGCGACTTACGAAATAATGATGTTGGCACCAGTTCC
CCCTGGATGGGCTATAGCCAGAACATTTACTTCAACTCTACCTTAGTAGATACAAGTAGAGAATATGGAGAGGATCATTACATTGAAAAG
TAAATGTTTTATTAGTTCATTGCCTGCACTTACTGATCGGAAGAGAGAAAGAACAGTTTCAGTATTGAGATGGCTCAGGAGAGGCTCTTT
GATTTTTAAAGTTTTGGGGTGGGGGATTGTGTGTGGTTTCTTTCTTTTGAATTTTAATTTAGGTGTTTTGGGTTTTTTTCCTTTAAAGAG
AATAGTGTTCACAAAATTTGAGCTGCTCTTTGGCTTTTGCTATAAGGGAAACAGAGTGGCCTGGCTGATTTGAATAAATGTTTCTTTCCT
CTCCACCATCTCACATTTTGCTTTTAAGTGAACACTTTTTCCCCATTGAGCATCTTGAACATACTTTTTTTCCAAATAAATTACTCATCC
TTAAAGTTTACTCCACTTTGACAAAAGATACGCCCTTCTCCCTGCACATAAAGCAGGTTGTAGAACGTGGCATTCTTGGGCAAGTAGGTA
GACTTTACCCAGTCTCTTTCCTTTTTTGCTGATGTGTGCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT
CTCTGTCTCGCTTGCTCGCTCTCGCTGTTTCTCTCTCTTTGAGGCATTTGTTTGGAAAAAATCGTTGAGATGCCCAAGAACCTGGGATAA
TTCTTTACTTTTTTTGAAATAAAGGAAAGGAAATTCAGACTCTTACATTGTTCTCTGTAACTCTTCAATTCTAAAATGTTTTGTTTTTTA
AACCATGTTCTGATGGGGAAGTTGATTTGTAAGTGTGGACAGCTTGGACATTGCTGCTGAGCTGTGGTTAGAGATGATGCCTCCATTCCT
AGAGGGCTAATAACAGCATTTAGCATATTGTTTACACATATATTTTTATGTCAAAAAAAAAACAAAAACCTTTCAAACAGAGCATTGTGA
TATTGTCAAAGAGAAAAACAAATCCTGAAGATACATGGAAATGTAACCTAGTTTAGGGTGGGTATTTTTCTGAAGATACATCAATACCTG
ACCTTTTTTAAAAAAATAATTTTAAAACAGCATACTGTGAGGAAGAACAGTATTGACATACCCACATCCCAGCATGTGTACCCTGCCAGT
TCTTTTAGGGATTTTTCCTCCAAAGAGATTTGGATTTGGTTTTGGTAAAAGGGGTTAAATTGTGCTTCCAGGCAAGAACTTTGCCTTATC
ATAAACAGGAAATGAAAAAGGGAAGGGCTGTCAGGATGGGATAATTTGGGAGGCTTCTCATTCTGGCTTCTATTTCTATGTGAGTACCAG
CATATAGAGTGTTTTAAAAACAGATACATGTCATATAATTTATCTGCACAGACTTAGACCTTCAGGAAACATAGGTTAAGCCCCCTTTTA
CAAAGAAAAAGTAAACATACTTCAGCATCTTGGAGGGTAGTTTTCAAAACTCAAGTTTCATGTTTCAATGCCAAGTTCTTATTTTAAAAA
ATAAAATCTACTTATAAGAGAAAGGTGCATTACTTAAAAAAAAAAAACTTTAAAGAAATGAAAGAAGAACCCTCTTCAGATACTTACTTG
AAGACTGTTTTCCCCTGTTAATGAGATATAGCTAGATATCGGTGTGTGTATTTCTTTATTATTCTCTGGTTTTTGATCTGGCCTTGCCTC
CAGGGCCAAACACTGATTTAGAAAGAGAGCCTTCTAGCTATTTTGGCATTGATGGCTTTTTATACCAGTGTGTCCAGTTAGATTTACTAG
GCTTACTGACATGCTATTGGTAAATCGCATTAAAGTTCATCTGAACCTTCTGTCTGTTGACTTCTTAGTCCTCAGACATGGGCCTTTGTG
TTTTAGAATATTTGAATTTGAGTTATTGGGCCCCACTCCCTGTTTTTTATTAAAGAACGTGAGCCTGGGATACTTTCAGAAGTATCTGTT
CAATGAAAAAAAGTTGGTTTCCCATCAAATATGAATAAAATTCTCTATATATTTCATTGTATTTTGGTTATCAGCAGTCATCAATAATGT
TTTTCCCTCCCCTCTCCCACCTCTTATTTTTAATTATGCCAAATATCCTAAATAATATACTTAAGCCTCCATTCCCTCATCCCTACTAGG
GAAGGGGGTGAGTGTATGTGTGAGTGTATGTGTATGTATGATCCCATCTCACCCCCACCCCCATTTTGGGAGTCTTTTAAAATGAAAACA
AAGTTTGGTAGTTTTGACTATTTCTAAAAGCAGAGGAGAAAAAAAAACTTATTTAAATATCCTGGAATCTGTATGGAGGAAGAAAAGGTA
TTTGTTAATTTTTCAGTTACGTTATCTATAAACATGATGGAAGTAAAGGTTTGGCAGAATTTCACCTTGACTATTTGAAAATTACAGACC
CAATTAATTCCATTCAAAAGTGGTTTTCGTTTTGTTTTAATTATTGTACAATGAGAGATATTGTCTATTAAATACATTATTTTGAACAGA
TGAGAAATCTGATTCTGTTCATGAGTGGGAGGCAAAACTGGTTTGACCGTGATCATTTTTGTGGTTTTGAAAACAAATATACTTGACCCA
GTTTCCTTAGTTTTTTCTTCAACTGTCCATAGGAACGATAAGTATTTGAAAGCAACATCAAATCTATACGTTTAAAGCAGGGCAGTTAGC
ACAAATTTGCAAGTAGAACTTCTATTAGCTTATGCCATAGACATCACCCAACCACTTGTATGTGTGTGTGTATATATAATATGCATATAT
AGTTACCGTGCTAAAATGGTTACCAGCAGGTTTTGAGAGAGAATGCTGCATCAGAAAAGTGTCAGTTGCCACCTCATTCTCCCTGATTTA
GGTTCCTGACACTGATTCCTTTCTCTCTCGTTTTTGACCCCCATTGGGTGTATCTTGTCTATGTACAGATATTTTGTAATATATTAAATT
TTTTTCTTTCAGTTTATAAAAATGGAAAGTGGAGATTGGAAAATTAAATATTTCCTGTTACTATACCACTTTTGCTCCATTGCATTTACT
TCTTAATCTGTACCCCCTGAGCATATCTAATCATGTATAAAGGACGTTTTTCCTCCACTTTATCTTAGGGGTTCTCTGTCTCAGAATCAT
TATAGACTCATTAACTCCCCCTCCCAGCAAAAGGTTATCAGGATTTGAAGAGGTGCTTGAAAACGCTAGACTAGGAACTAGAGAATAAAT
GAGTTGGGAAAAACCATGAAATGTGATTTTTTTAAAGTAGAAAAGTTATACAAATAATGGTACCAAACCATCAAAAGAGTTGAGCTTCAT
GTACCCTGACTCCTCCTGACAGGAGAGGTAAGTGGGTTTGAGCTCAACTGTCATCAAGGGAAGTTGGTAAGAGGCTGTTTAGACCCAAAG
GATAGTCTTAAACCAGACTTCACCACCCACCCTACCTCAGTTCCCATGTTATTACATGCAGAGTCAGCATGGGGATTAGTGTACCTACCT
TTGCTGAGATTTCCCGATGCGTTGCCAATCCAGAAAGTGAATCAAAAAGTTGTTTAAAAGTTAAAATCTCTATTGTTTCCAAAATCTTTC

>95378_95378_26_TUBD1-CDK12_TUBD1_chr17_57955464_ENST00000394239_CDK12_chr17_37667782_ENST00000447079_length(amino acids)=592AA_BP=
MWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSF
IPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEP
VKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQ
DSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPH
ILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGF
SAIDTDERNSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQ

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Fusion Gene PPI Analysis for TUBD1-CDK12


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TUBD1-CDK12


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TUBD1-CDK12


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource