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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TUFT1-PKN2 (FusionGDB2 ID:95436)

Fusion Gene Summary for TUFT1-PKN2

check button Fusion gene summary
Fusion gene informationFusion gene name: TUFT1-PKN2
Fusion gene ID: 95436
HgeneTgene
Gene symbol

TUFT1

PKN2

Gene ID

7286

5586

Gene nametuftelin 1protein kinase N2
Synonyms-PAK2|PRK2|PRKCL2|PRO2042|Pak-2|STK7
Cytomap

1q21.3

1p22.2

Type of geneprotein-codingprotein-coding
Descriptiontuftelinserine/threonine-protein kinase N2PKN gammacardiolipin-activated protein kinase Pak2protein kinase C-like 2protein-kinase C-related kinase 2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000353024, ENST00000368848, 
ENST00000368849, ENST00000392712, 
ENST00000538902, 		ENST00000370505, 
ENST00000370513, ENST00000495119, 
ENST00000544045, ENST00000316005, 
ENST00000370521, 
Fusion gene scores* DoF score10 X 6 X 10=6005 X 3 X 3=45
# samples 134
** MAII scorelog2(13/600*10)=-2.20645087746743
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/45*10)=-0.169925001442312
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TUFT1 [Title/Abstract] AND PKN2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTUFT1(151512902)-PKN2(89206671), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePKN2

GO:0006468

protein phosphorylation

17332740

TgenePKN2

GO:0010631

epithelial cell migration

21754995


check buttonFusion gene breakpoints across TUFT1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PKN2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A23U-01ATUFT1chr1

151512902

-PKN2chr1

89206671

+
ChimerDB4SARCTCGA-DX-A23U-01ATUFT1chr1

151512902

+PKN2chr1

89206671

+


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Fusion Gene ORF analysis for TUFT1-PKN2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000353024ENST00000370505TUFT1chr1

151512902

+PKN2chr1

89206671

+
5CDS-intronENST00000353024ENST00000370513TUFT1chr1

151512902

+PKN2chr1

89206671

+
5CDS-intronENST00000353024ENST00000495119TUFT1chr1

151512902

+PKN2chr1

89206671

+
5CDS-intronENST00000353024ENST00000544045TUFT1chr1

151512902

+PKN2chr1

89206671

+
5CDS-intronENST00000368848ENST00000370505TUFT1chr1

151512902

+PKN2chr1

89206671

+
5CDS-intronENST00000368848ENST00000370513TUFT1chr1

151512902

+PKN2chr1

89206671

+
5CDS-intronENST00000368848ENST00000495119TUFT1chr1

151512902

+PKN2chr1

89206671

+
5CDS-intronENST00000368848ENST00000544045TUFT1chr1

151512902

+PKN2chr1

89206671

+
5CDS-intronENST00000368849ENST00000370505TUFT1chr1

151512902

+PKN2chr1

89206671

+
5CDS-intronENST00000368849ENST00000370513TUFT1chr1

151512902

+PKN2chr1

89206671

+
5CDS-intronENST00000368849ENST00000495119TUFT1chr1

151512902

+PKN2chr1

89206671

+
5CDS-intronENST00000368849ENST00000544045TUFT1chr1

151512902

+PKN2chr1

89206671

+
5CDS-intronENST00000392712ENST00000370505TUFT1chr1

151512902

+PKN2chr1

89206671

+
5CDS-intronENST00000392712ENST00000370513TUFT1chr1

151512902

+PKN2chr1

89206671

+
5CDS-intronENST00000392712ENST00000495119TUFT1chr1

151512902

+PKN2chr1

89206671

+
5CDS-intronENST00000392712ENST00000544045TUFT1chr1

151512902

+PKN2chr1

89206671

+
5UTR-3CDSENST00000538902ENST00000316005TUFT1chr1

151512902

+PKN2chr1

89206671

+
5UTR-3CDSENST00000538902ENST00000370521TUFT1chr1

151512902

+PKN2chr1

89206671

+
5UTR-intronENST00000538902ENST00000370505TUFT1chr1

151512902

+PKN2chr1

89206671

+
5UTR-intronENST00000538902ENST00000370513TUFT1chr1

151512902

+PKN2chr1

89206671

+
5UTR-intronENST00000538902ENST00000495119TUFT1chr1

151512902

+PKN2chr1

89206671

+
5UTR-intronENST00000538902ENST00000544045TUFT1chr1

151512902

+PKN2chr1

89206671

+
In-frameENST00000353024ENST00000316005TUFT1chr1

151512902

+PKN2chr1

89206671

+
In-frameENST00000353024ENST00000370521TUFT1chr1

151512902

+PKN2chr1

89206671

+
In-frameENST00000368848ENST00000316005TUFT1chr1

151512902

+PKN2chr1

89206671

+
In-frameENST00000368848ENST00000370521TUFT1chr1

151512902

+PKN2chr1

89206671

+
In-frameENST00000368849ENST00000316005TUFT1chr1

151512902

+PKN2chr1

89206671

+
In-frameENST00000368849ENST00000370521TUFT1chr1

151512902

+PKN2chr1

89206671

+
In-frameENST00000392712ENST00000316005TUFT1chr1

151512902

+PKN2chr1

89206671

+
In-frameENST00000392712ENST00000370521TUFT1chr1

151512902

+PKN2chr1

89206671

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000353024TUFT1chr1151512902+ENST00000316005PKN2chr189206671+2347122441888614
ENST00000353024TUFT1chr1151512902+ENST00000370521PKN2chr189206671+5836122443028994
ENST00000392712TUFT1chr1151512902+ENST00000316005PKN2chr189206671+2347122441888614
ENST00000392712TUFT1chr1151512902+ENST00000370521PKN2chr189206671+5836122443028994
ENST00000368849TUFT1chr1151512902+ENST00000316005PKN2chr189206671+2347122441888614
ENST00000368849TUFT1chr1151512902+ENST00000370521PKN2chr189206671+5836122443028994
ENST00000368848TUFT1chr1151512902+ENST00000316005PKN2chr189206671+2344119411885614
ENST00000368848TUFT1chr1151512902+ENST00000370521PKN2chr189206671+5833119413025994

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000353024ENST00000316005TUFT1chr1151512902+PKN2chr189206671+0.0004092660.9995907
ENST00000353024ENST00000370521TUFT1chr1151512902+PKN2chr189206671+4.42E-050.9999558
ENST00000392712ENST00000316005TUFT1chr1151512902+PKN2chr189206671+0.0004092660.9995907
ENST00000392712ENST00000370521TUFT1chr1151512902+PKN2chr189206671+4.42E-050.9999558
ENST00000368849ENST00000316005TUFT1chr1151512902+PKN2chr189206671+0.0004092660.9995907
ENST00000368849ENST00000370521TUFT1chr1151512902+PKN2chr189206671+4.42E-050.9999558
ENST00000368848ENST00000316005TUFT1chr1151512902+PKN2chr189206671+0.0004134330.9995865
ENST00000368848ENST00000370521TUFT1chr1151512902+PKN2chr189206671+4.44E-050.99995565

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Fusion Genomic Features for TUFT1-PKN2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TUFT1chr1151512902+PKN2chr189206670+3.40E-081
TUFT1chr1151512902+PKN2chr189206670+3.40E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for TUFT1-PKN2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:151512902/chr1:89206671)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePKN2chr1:151512902chr1:89206671ENST00000370505021121_2030828.0DomainREM-1 2
TgenePKN2chr1:151512902chr1:89206671ENST00000370505021204_2840828.0DomainREM-1 3
TgenePKN2chr1:151512902chr1:89206671ENST0000037050502133_1090828.0DomainREM-1 1
TgenePKN2chr1:151512902chr1:89206671ENST00000370505021353_4730828.0DomainC2
TgenePKN2chr1:151512902chr1:89206671ENST00000370505021657_9160828.0DomainProtein kinase
TgenePKN2chr1:151512902chr1:89206671ENST00000370505021917_9840828.0DomainAGC-kinase C-terminal
TgenePKN2chr1:151512902chr1:89206671ENST00000370513021121_20316937.0DomainREM-1 2
TgenePKN2chr1:151512902chr1:89206671ENST00000370513021204_28416937.0DomainREM-1 3
TgenePKN2chr1:151512902chr1:89206671ENST0000037051302133_10916937.0DomainREM-1 1
TgenePKN2chr1:151512902chr1:89206671ENST00000370513021353_47316937.0DomainC2
TgenePKN2chr1:151512902chr1:89206671ENST00000370513021657_91616937.0DomainProtein kinase
TgenePKN2chr1:151512902chr1:89206671ENST00000370513021917_98416937.0DomainAGC-kinase C-terminal
TgenePKN2chr1:151512902chr1:89206671ENST00000370521022121_20316985.0DomainREM-1 2
TgenePKN2chr1:151512902chr1:89206671ENST00000370521022204_28416985.0DomainREM-1 3
TgenePKN2chr1:151512902chr1:89206671ENST0000037052102233_10916985.0DomainREM-1 1
TgenePKN2chr1:151512902chr1:89206671ENST00000370521022353_47316985.0DomainC2
TgenePKN2chr1:151512902chr1:89206671ENST00000370521022657_91616985.0DomainProtein kinase
TgenePKN2chr1:151512902chr1:89206671ENST00000370521022917_98416985.0DomainAGC-kinase C-terminal
TgenePKN2chr1:151512902chr1:89206671ENST00000544045017121_2030659.0DomainREM-1 2
TgenePKN2chr1:151512902chr1:89206671ENST00000544045017204_2840659.0DomainREM-1 3
TgenePKN2chr1:151512902chr1:89206671ENST0000054404501733_1090659.0DomainREM-1 1
TgenePKN2chr1:151512902chr1:89206671ENST00000544045017353_4730659.0DomainC2
TgenePKN2chr1:151512902chr1:89206671ENST00000544045017657_9160659.0DomainProtein kinase
TgenePKN2chr1:151512902chr1:89206671ENST00000544045017917_9840659.0DomainAGC-kinase C-terminal
TgenePKN2chr1:151512902chr1:89206671ENST00000370505021663_6710828.0Nucleotide bindingATP
TgenePKN2chr1:151512902chr1:89206671ENST00000370513021663_67116937.0Nucleotide bindingATP
TgenePKN2chr1:151512902chr1:89206671ENST00000370521022663_67116985.0Nucleotide bindingATP
TgenePKN2chr1:151512902chr1:89206671ENST00000544045017663_6710659.0Nucleotide bindingATP
TgenePKN2chr1:151512902chr1:89206671ENST00000370505021382_4630828.0RegionNecessary to rescue apical junction formation
TgenePKN2chr1:151512902chr1:89206671ENST00000370505021917_9770828.0RegionNote=Necessary for the catalytic activity
TgenePKN2chr1:151512902chr1:89206671ENST00000370505021978_9840828.0RegionNote=Negatively regulates the responsiveness of the catalytic activity by cardiolipin and is required for optimal activation by the GTP-bound RhoA
TgenePKN2chr1:151512902chr1:89206671ENST00000370513021382_46316937.0RegionNecessary to rescue apical junction formation
TgenePKN2chr1:151512902chr1:89206671ENST00000370513021917_97716937.0RegionNote=Necessary for the catalytic activity
TgenePKN2chr1:151512902chr1:89206671ENST00000370513021978_98416937.0RegionNote=Negatively regulates the responsiveness of the catalytic activity by cardiolipin and is required for optimal activation by the GTP-bound RhoA
TgenePKN2chr1:151512902chr1:89206671ENST00000370521022382_46316985.0RegionNecessary to rescue apical junction formation
TgenePKN2chr1:151512902chr1:89206671ENST00000370521022917_97716985.0RegionNote=Necessary for the catalytic activity
TgenePKN2chr1:151512902chr1:89206671ENST00000370521022978_98416985.0RegionNote=Negatively regulates the responsiveness of the catalytic activity by cardiolipin and is required for optimal activation by the GTP-bound RhoA
TgenePKN2chr1:151512902chr1:89206671ENST00000544045017382_4630659.0RegionNecessary to rescue apical junction formation
TgenePKN2chr1:151512902chr1:89206671ENST00000544045017917_9770659.0RegionNote=Necessary for the catalytic activity
TgenePKN2chr1:151512902chr1:89206671ENST00000544045017978_9840659.0RegionNote=Negatively regulates the responsiveness of the catalytic activity by cardiolipin and is required for optimal activation by the GTP-bound RhoA

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTUFT1chr1:151512902chr1:89206671ENST00000353024+111162_35120332.0Coiled coilOntology_term=ECO:0000255
HgeneTUFT1chr1:151512902chr1:89206671ENST00000353024+11188_12620332.0Coiled coilOntology_term=ECO:0000255
HgeneTUFT1chr1:151512902chr1:89206671ENST00000368848+112162_35120366.0Coiled coilOntology_term=ECO:0000255
HgeneTUFT1chr1:151512902chr1:89206671ENST00000368848+11288_12620366.0Coiled coilOntology_term=ECO:0000255
HgeneTUFT1chr1:151512902chr1:89206671ENST00000368849+113162_35120391.0Coiled coilOntology_term=ECO:0000255
HgeneTUFT1chr1:151512902chr1:89206671ENST00000368849+11388_12620391.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for TUFT1-PKN2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>95436_95436_1_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000353024_PKN2_chr1_89206671_ENST00000316005_length(transcript)=2347nt_BP=122nt
GCCCAGTTGGAGCCAGACAGCGGGGTGGACAAGTGGCGTGTGTGCTGCGACCCCGAGGGAAGATGAACGGGACGCGGAACTGGTGTACCC
TGGTGGACGTGCACCCAGAGGACCAGGCGGCGGGGGATTCCCGAAGTCTTCCGTTTTCTGAGAATGTGAGTGCTGTTCAAAAATTAGACT
TTTCAGATACAATGGTGCAGCAGAAATTGGATGATATCAAGGATCGAATTAAGAGAGAAATAAGGAAAGAACTGAAAATCAAAGAAGGAG
CTGAAAATCTGAGGAAAGTCACAACAGATAAAAAAAGTTTGGCTTATGTAGACAACATTTTGAAAAAATCAAATAAAAAATTAGAAGAAC
TACATCACAAGCTGCAGGAATTAAATGCACATATTGTTGTATCAGATCCAGAAGATATTACAGATTGCCCAAGGACTCCAGATACTCCAA
ATAATGACCCTCGTTGTTCTACTAGCAACAATAGATTGAAGGCCTTACAAAAACAATTGGATATAGAACTTAAAGTAAAACAAGGTGCAG
AGAATATGATACAGATGTATTCAAATGGATCTTCAAAGGATCGGAAACTCCATGGTACAGCTCAGCAACTGCTCCAGGACAGCAAGACAA
AAATAGAAGTCATACGAATGCAGATTCTTCAGGCAGTCCAGACTAATGAATTGGCTTTTGATAATGCAAAACCTGTGATAAGTCCTCTTG
AACTTCGGATGGAAGAATTAAGGCATCATTTTAGGATAGAGTTTGCAGTAGCAGAAGGTGCAAAGAATGTAATGAAATTACTTGGCTCAG
GAAAAGTAACAGACAGAAAAGCACTTTCAGAAGCTCAAGCAAGATTTAATGAATCAAGTCAGAAGTTGGACCTTTTAAAGTATTCATTAG
AGCAAAGATTAAACGAAGTCCCCAAGAATCATCCCAAAAGCAGGATTATTATTGAAGAACTTTCACTTGTTGCTGCATCACCAACACTAA
GTCCACGTCAAAGTATGATATCTACGCAAAATCAATATAGTACACTATCCAAACCAGCAGCACTAACAGGTACTTTGGAAGTTCGTCTTA
TGGGCTGCCAAGATATCCTAGAGAATGTCCCTGGACGGTCAAAAGCAACATCAGTTGCACTGCCTGGTTGGAGTCCAAGTGAAACCAGAT
CATCTTTCATGAGCAGAACGAGTAAAAGTAAAAGCGGAAGTAGTCGAAATCTTCTAAAAACCGATGACTTGTCCAATGATGTCTGTGCTG
TTTTGAAGCTCGATAATACTGTGGTTGGCCAAACTAGCTGGAAACCCATTTCCAATCAGTCATGGGACCAGAAGTTTACACTGGAACTGG
ACAGGTCACGTGAACTGGAAATTTCAGTTTATTGGCGTGATTGGCGGTCTCTGTGTGCTGTAAAATTTCTGAGGTTAGAAGATTTTTTAG
ACAACCAACGGCATGGCATGTGTCTCTATTTGGAACCACAGGGTACTTTATTTGCAGAGGTTACCTTTTTTAATCCAGTTATTGAAAGAA
GACCAAAACTTCAAAGACAAAAGAAAATTTTTTCAAAGCAACAAGGCAAAACATTTCTCAGAGCTCCTCAAATGAATATTAATATTGCCA
CTTGGGGAAGGCTAGTAAGAAGAGCTATTCCTACAGTAAATCATTCTGGCACCTTCAGCCCTCAAGCTCCTGTGCCTACTACAGTGCCAG
TGGTTGATGTACGCATCCCTCAACTAGCACCTCCAGCTAGGTATGTGTCTGAGATTTTAAGCATCTCTTATACAAAGTTATTGGGACATT
CTTACGTACTGATTATAGCAGGTGTACTGAGTCTTGCTTTTTTCCCAAGTAGTATTTTGAAAGTAGTGTTCTGTTTACTTAAAAAGTAAA
TTGTTTGCTTTAATTTTAAAGCTGTTTAAAATACAGACTTTCTATTACTGTTTTGGTGAGTTACTTTATCTTCTATAAGTGATTCTACAG
TAACCAAATTGGACTTTGATCTTGAGCCTGAACCTCCTCCAGCCCCACCACGAGCTTCTTCTCTTGGAGAAATAGATGAATCTTCTGAAT
TAAGAGTTTTGGATATACCAGGACAGGCAAGCCATTTTAAACCTTGCATAATTCCTCTTCACTGAATGAATTAGCAATAAAAGCATCATA
GTGAATAAGGCGTGTCTTTCCATTTAAAATTGCCACTGAACTGTGAATTTATGGTTTTTTGTTTGTTTTTTGTTTTTGTTTTTGTTTTTT
GAGACAGAGTTTCACTCTTGTTACCCAGGCTGGAGTGCAATGGCATGATCTCGGCTCACTGCAACCTCCGCCTCCCGGATTCAAGCGATT

>95436_95436_1_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000353024_PKN2_chr1_89206671_ENST00000316005_length(amino acids)=614AA_BP=26
MRPRGKMNGTRNWCTLVDVHPEDQAAGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKELKIKEGAENLRKVTTDKKSLA
YVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPRTPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDR
KLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQAR
FNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVAASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSK
ATSVALPGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRDW
RSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNH

--------------------------------------------------------------
>95436_95436_2_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000353024_PKN2_chr1_89206671_ENST00000370521_length(transcript)=5836nt_BP=122nt
GCCCAGTTGGAGCCAGACAGCGGGGTGGACAAGTGGCGTGTGTGCTGCGACCCCGAGGGAAGATGAACGGGACGCGGAACTGGTGTACCC
TGGTGGACGTGCACCCAGAGGACCAGGCGGCGGGGGATTCCCGAAGTCTTCCGTTTTCTGAGAATGTGAGTGCTGTTCAAAAATTAGACT
TTTCAGATACAATGGTGCAGCAGAAATTGGATGATATCAAGGATCGAATTAAGAGAGAAATAAGGAAAGAACTGAAAATCAAAGAAGGAG
CTGAAAATCTGAGGAAAGTCACAACAGATAAAAAAAGTTTGGCTTATGTAGACAACATTTTGAAAAAATCAAATAAAAAATTAGAAGAAC
TACATCACAAGCTGCAGGAATTAAATGCACATATTGTTGTATCAGATCCAGAAGATATTACAGATTGCCCAAGGACTCCAGATACTCCAA
ATAATGACCCTCGTTGTTCTACTAGCAACAATAGATTGAAGGCCTTACAAAAACAATTGGATATAGAACTTAAAGTAAAACAAGGTGCAG
AGAATATGATACAGATGTATTCAAATGGATCTTCAAAGGATCGGAAACTCCATGGTACAGCTCAGCAACTGCTCCAGGACAGCAAGACAA
AAATAGAAGTCATACGAATGCAGATTCTTCAGGCAGTCCAGACTAATGAATTGGCTTTTGATAATGCAAAACCTGTGATAAGTCCTCTTG
AACTTCGGATGGAAGAATTAAGGCATCATTTTAGGATAGAGTTTGCAGTAGCAGAAGGTGCAAAGAATGTAATGAAATTACTTGGCTCAG
GAAAAGTAACAGACAGAAAAGCACTTTCAGAAGCTCAAGCAAGATTTAATGAATCAAGTCAGAAGTTGGACCTTTTAAAGTATTCATTAG
AGCAAAGATTAAACGAAGTCCCCAAGAATCATCCCAAAAGCAGGATTATTATTGAAGAACTTTCACTTGTTGCTGCATCACCAACACTAA
GTCCACGTCAAAGTATGATATCTACGCAAAATCAATATAGTACACTATCCAAACCAGCAGCACTAACAGGTACTTTGGAAGTTCGTCTTA
TGGGCTGCCAAGATATCCTAGAGAATGTCCCTGGACGGTCAAAAGCAACATCAGTTGCACTGCCTGGTTGGAGTCCAAGTGAAACCAGAT
CATCTTTCATGAGCAGAACGAGTAAAAGTAAAAGCGGAAGTAGTCGAAATCTTCTAAAAACCGATGACTTGTCCAATGATGTCTGTGCTG
TTTTGAAGCTCGATAATACTGTGGTTGGCCAAACTAGCTGGAAACCCATTTCCAATCAGTCATGGGACCAGAAGTTTACACTGGAACTGG
ACAGGTCACGTGAACTGGAAATTTCAGTTTATTGGCGTGATTGGCGGTCTCTGTGTGCTGTAAAATTTCTGAGGTTAGAAGATTTTTTAG
ACAACCAACGGCATGGCATGTGTCTCTATTTGGAACCACAGGGTACTTTATTTGCAGAGGTTACCTTTTTTAATCCAGTTATTGAAAGAA
GACCAAAACTTCAAAGACAAAAGAAAATTTTTTCAAAGCAACAAGGCAAAACATTTCTCAGAGCTCCTCAAATGAATATTAATATTGCCA
CTTGGGGAAGGCTAGTAAGAAGAGCTATTCCTACAGTAAATCATTCTGGCACCTTCAGCCCTCAAGCTCCTGTGCCTACTACAGTGCCAG
TGGTTGATGTACGCATCCCTCAACTAGCACCTCCAGCTAGTGATTCTACAGTAACCAAATTGGACTTTGATCTTGAGCCTGAACCTCCTC
CAGCCCCACCACGAGCTTCTTCTCTTGGAGAAATAGATGAATCTTCTGAATTAAGAGTTTTGGATATACCAGGACAGGATTCAGAGACTG
TTTTTGATATTCAGAATGACAGAAATAGTATACTTCCAAAATCTCAATCTGAATACAAGCCTGATACTCCTCAGTCAGGCCTAGAATATA
GTGGTATTCAAGAACTTGAGGACAGAAGATCTCAGCAAAGGTTTCAGTTTAATCTACAAGATTTCAGGTGTTGTGCTGTCTTGGGAAGAG
GACATTTTGGAAAGGTGCTTTTAGCTGAATATAAAAACACAAATGAGATGTTTGCTATAAAAGCCTTAAAGAAAGGAGATATTGTGGCTC
GAGATGAAGTAGACAGCCTGATGTGTGAAAAAAGAATTTTTGAAACTGTGAATAGTGTAAGGCATCCCTTTTTGGTGAACCTTTTTGCAT
GTTTCCAAACCAAAGAGCATGTTTGCTTTGTAATGGAATATGCTGCCGGTGGGGACCTAATGATGCACATTCATACTGATGTCTTTTCTG
AACCAAGAGCTGTATTTTATGCTGCTTGTGTAGTTCTTGGGTTGCAGTATTTACATGAACACAAAATTGTTTATAGAGATTTGAAATTGG
ATAACTTATTGCTAGATACAGAGGGCTTTGTGAAAATTGCTGATTTTGGTCTTTGCAAAGAAGGAATGGGATATGGAGATAGAACAAGCA
CATTTTGTGGCACTCCTGAATTTCTTGCCCCAGAAGTATTAACAGAAACTTCTTATACAAGGGCTGTAGATTGGTGGGGCCTTGGCGTGC
TTATATATGAAATGCTTGTTGGTGAGTCTCCCTTTCCTGGTGATGATGAAGAGGAAGTTTTTGACAGTATTGTAAATGATGAAGTAAGGT
ATCCAAGGTTCTTATCTACAGAAGCCATTTCTATAATGAGAAGGCTGTTAAGAAGAAATCCTGAACGGCGCCTTGGGGCTAGCGAGAAAG
ATGCAGAGGATGTAAAAAAGCACCCATTTTTCCGGCTAATTGATTGGAGCGCTCTGATGGACAAAAAAGTAAAGCCACCATTTATACCTA
CCATAAGAGGACGAGAAGATGTTAGTAATTTTGATGATGAATTTACCTCAGAAGCACCTATTCTGACTCCACCTCGAGAACCAAGGATAC
TTTCGGAAGAGGAGCAGGAAATGTTCAGAGATTTTGACTACATTGCTGATTGGTGTTAAGTTGCTAGACACTGCGAAACCAAGCTGACTC
ACAAGAAGACCTCTTAAAAATAGCAACCCTTCATTTGCTCTCTGTGCCACCAATAGCTTCTGAGTTTTTTGTTGTTGTTGTTTTTATTGA
AACACGTGAAGATTTGTTTAAAAGTACCATTCTAATACTTCTTCAAAAGTGGCTCCTCATTGTACTTCAGCGTAAATATGAGCACTGGAA
ACAGTTTCATGGAGTTTAAGTTGAGTGAACATCGGCCATGAAAATCCATCACGAATACTTTTGGATCAATAGTCTATTTTTAAAAAGAAA
GAAAAAAACCACTTTTTTATAGTCCCTAGCTTTGCCATATGCCCGCCTTAAGTGGAAGGAAAGTTAATCACTTAACTATGTTTTATAAAA
AGAAAAAAGGGCTTGGAATGCTATTACTGTTCACACAAAGTATGATTCTGTTTGAATAAGGCAAATGCTCCTTTTTTTAAAAAAAAAGAC
ATTACTGTAATATCAAAAACCGTGGCAGTTTGTATACAACTCGGGGCTTGATTTTTTTTAAAAAAACAGAATGAATTGATGTCTTATTTT
ATAAATGTTCTATATTTATTAGGAGAAAACTTTATATTGCCTTTTTTATCAATCATGTAACAGGCTTATAGCTTTCCAACAGAGCTGCTT
GCCAAACAATTTTTTTTGTTTATTAAACAGTGCTGAAACAAACAGGATCAGCATTTACTTAAGATGTTAAGAATGAGGACTTTTAATCAG
CCGAACCAAGATATTGTTACCTGTATGCATTCCCAAAGTCTAGATGCTCAGTATGTTCAGTCATATCTTTCAGAATCAGTGAACCGATTA
CCCTTTTTTTGGTATTCACTCTACATCTGCCAACCTAGTTCACCTTGGTTTTGTGTCTGCTGTAGAAGGGAACCATAACTTGGTTAAACC
GTAGGGATTATCATTGTATACATGCTGTGAACATGTATATGTGCAAGTTTTAATGTATTCTATGTTGTAGGCTTATTATTTAATTTTACC
ACTTCATCACTTTTGTACAGTGGCCAAGCAGACACCTCAAACTCCAGCATTTACATTAAGTGCATTTGTACATTTTAGGCCACTGGATCC
AGATTTTATATTGGCAGTTATTGAGGGCAAAAGCAATATATTGTAACAGAATGTATAAATATTTTTGATAAAACAGTCTATATTTTATTA
AAAAATGAATTATAACACTAAAGCTGTACCTCAAAAGTCTCAAAAATAATTTGATGAAATATTTTATACAACTCTTCAAAGGATCCGTCT
GTGGCTTTTTATACTCTTTTAGGGTTGTCTTTTTACAAACCATGACTTTCCACTTGCCTGTAGTTTTTTGTTTGTTTTGGTTTGGTTTGA
TTTTATATTTTTTTCTCCTAATCTATGACTTTATTGTTTTTTCTTAGTTTAGTAATAGCATCTTTGATCCTGTGCTTAGCATGTTAGGGT
CATTATACCTCAGGAATAGCAAGCTGTTAAGTAACCATACTGAATTAACTATTTAATTACAGTGAGCTCATCTCTTAAAAATTGTTCAGG
TGTAAATCTTATGAGAAACATGAAAAAGCACACTGATTTATGGAGAGTTGAGCTAAAAACATTTATAAATATTTGCTGGGATGTTTTAGC
ATCTTTTCATTGTACTCTGAGAACAATTAAAATTGTCCAGAGATCATTTATATTACCTTCCAAATTGTTTATTACCCAAGATCCTTTGGG
AGAAAATCTTATAGAATGGGGGAACAATATGTGGTTTAAAGTTATTTTAAAATGCCAGTTAATTTCCTCGGCAAAGGACAATAGAGGAAC
TTAGCTTAATTGTCTGGCTTTAATTTAAACTGTGTTAATACAACATTAAAATAAAACACTAAATACTTTTGAGGTACAGTCTGCTCACTT
TTTTGGTTCTCAAATAGCAAAGAAAGTAATGTCTAAAATAGGCTCTTAGCATTAAAAACTGACAGCATTTCGTAACTACACAGTGTACAG
AATTTTTTTTTAATTGAAGTCAATCACTAAAAAAATTAGAAGGCAGGGTCTATTTACACAATTAAGCTGAAGAAAGCACTAATTTTTTGT
AGTTTAAAATATATATATATTTTAGTCAGATTTAAAATTTTAAGCTTTATAGAGTGTAAATATATTTTGCTATTACTGTATGTGTATGTG
ACTGCTCAAGCACTTTGTAAAGAAATTAGGATATTTTAGAATGGTACACTATGCATTCAAATGAAATGTGCCTTTCACTATGTCATTCTA
AGAAAACAAGTGTTTTTTGCAGTCATAAATTATCACAAATGCACAAATTAAAGTCTATATAGATTGAAATTTGTAACTTTGGTTTTAAGT
ATTCTTTCCTTTTAGAAACTTCCTAATGATTAAAATATACTTTAACTTTTCTGTGTTCAAAATCTCAAAGACTAATTAACTTTAATAAAC
ATTCTTGCAAGTACTTTTTGTCCTAGTGAAGGCTTAAAACCATGAACATTCAGAGCAAACTGTCCACTTCATTGGGAATAATGGGAAAAG
TTTGTATTCTGCTCCTGTAAGGTCAGTAGCATCTTTTATTTGAAGCATATTTATGGACTGCTTACTGTGTATAGATACTGAGAATAGGAA
GTTTTTTTTTTTAAAGCAACAAAATGTTGATGAATGAAGAACAGCCTGTTTTAATTAAGATGCAAGCACCAGTATTGTATGTACTTTTCT

>95436_95436_2_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000353024_PKN2_chr1_89206671_ENST00000370521_length(amino acids)=994AA_BP=26
MRPRGKMNGTRNWCTLVDVHPEDQAAGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKELKIKEGAENLRKVTTDKKSLA
YVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPRTPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDR
KLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQAR
FNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVAASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSK
ATSVALPGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRDW
RSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNH
SGTFSPQAPVPTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPGQDSETVFDIQNDRNSILPKS
QSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFE
TVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIAD
FGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR
LLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYI

--------------------------------------------------------------
>95436_95436_3_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000368848_PKN2_chr1_89206671_ENST00000316005_length(transcript)=2344nt_BP=119nt
CAGTTGGAGCCAGACAGCGGGGTGGACAAGTGGCGTGTGTGCTGCGACCCCGAGGGAAGATGAACGGGACGCGGAACTGGTGTACCCTGG
TGGACGTGCACCCAGAGGACCAGGCGGCGGGGGATTCCCGAAGTCTTCCGTTTTCTGAGAATGTGAGTGCTGTTCAAAAATTAGACTTTT
CAGATACAATGGTGCAGCAGAAATTGGATGATATCAAGGATCGAATTAAGAGAGAAATAAGGAAAGAACTGAAAATCAAAGAAGGAGCTG
AAAATCTGAGGAAAGTCACAACAGATAAAAAAAGTTTGGCTTATGTAGACAACATTTTGAAAAAATCAAATAAAAAATTAGAAGAACTAC
ATCACAAGCTGCAGGAATTAAATGCACATATTGTTGTATCAGATCCAGAAGATATTACAGATTGCCCAAGGACTCCAGATACTCCAAATA
ATGACCCTCGTTGTTCTACTAGCAACAATAGATTGAAGGCCTTACAAAAACAATTGGATATAGAACTTAAAGTAAAACAAGGTGCAGAGA
ATATGATACAGATGTATTCAAATGGATCTTCAAAGGATCGGAAACTCCATGGTACAGCTCAGCAACTGCTCCAGGACAGCAAGACAAAAA
TAGAAGTCATACGAATGCAGATTCTTCAGGCAGTCCAGACTAATGAATTGGCTTTTGATAATGCAAAACCTGTGATAAGTCCTCTTGAAC
TTCGGATGGAAGAATTAAGGCATCATTTTAGGATAGAGTTTGCAGTAGCAGAAGGTGCAAAGAATGTAATGAAATTACTTGGCTCAGGAA
AAGTAACAGACAGAAAAGCACTTTCAGAAGCTCAAGCAAGATTTAATGAATCAAGTCAGAAGTTGGACCTTTTAAAGTATTCATTAGAGC
AAAGATTAAACGAAGTCCCCAAGAATCATCCCAAAAGCAGGATTATTATTGAAGAACTTTCACTTGTTGCTGCATCACCAACACTAAGTC
CACGTCAAAGTATGATATCTACGCAAAATCAATATAGTACACTATCCAAACCAGCAGCACTAACAGGTACTTTGGAAGTTCGTCTTATGG
GCTGCCAAGATATCCTAGAGAATGTCCCTGGACGGTCAAAAGCAACATCAGTTGCACTGCCTGGTTGGAGTCCAAGTGAAACCAGATCAT
CTTTCATGAGCAGAACGAGTAAAAGTAAAAGCGGAAGTAGTCGAAATCTTCTAAAAACCGATGACTTGTCCAATGATGTCTGTGCTGTTT
TGAAGCTCGATAATACTGTGGTTGGCCAAACTAGCTGGAAACCCATTTCCAATCAGTCATGGGACCAGAAGTTTACACTGGAACTGGACA
GGTCACGTGAACTGGAAATTTCAGTTTATTGGCGTGATTGGCGGTCTCTGTGTGCTGTAAAATTTCTGAGGTTAGAAGATTTTTTAGACA
ACCAACGGCATGGCATGTGTCTCTATTTGGAACCACAGGGTACTTTATTTGCAGAGGTTACCTTTTTTAATCCAGTTATTGAAAGAAGAC
CAAAACTTCAAAGACAAAAGAAAATTTTTTCAAAGCAACAAGGCAAAACATTTCTCAGAGCTCCTCAAATGAATATTAATATTGCCACTT
GGGGAAGGCTAGTAAGAAGAGCTATTCCTACAGTAAATCATTCTGGCACCTTCAGCCCTCAAGCTCCTGTGCCTACTACAGTGCCAGTGG
TTGATGTACGCATCCCTCAACTAGCACCTCCAGCTAGGTATGTGTCTGAGATTTTAAGCATCTCTTATACAAAGTTATTGGGACATTCTT
ACGTACTGATTATAGCAGGTGTACTGAGTCTTGCTTTTTTCCCAAGTAGTATTTTGAAAGTAGTGTTCTGTTTACTTAAAAAGTAAATTG
TTTGCTTTAATTTTAAAGCTGTTTAAAATACAGACTTTCTATTACTGTTTTGGTGAGTTACTTTATCTTCTATAAGTGATTCTACAGTAA
CCAAATTGGACTTTGATCTTGAGCCTGAACCTCCTCCAGCCCCACCACGAGCTTCTTCTCTTGGAGAAATAGATGAATCTTCTGAATTAA
GAGTTTTGGATATACCAGGACAGGCAAGCCATTTTAAACCTTGCATAATTCCTCTTCACTGAATGAATTAGCAATAAAAGCATCATAGTG
AATAAGGCGTGTCTTTCCATTTAAAATTGCCACTGAACTGTGAATTTATGGTTTTTTGTTTGTTTTTTGTTTTTGTTTTTGTTTTTTGAG
ACAGAGTTTCACTCTTGTTACCCAGGCTGGAGTGCAATGGCATGATCTCGGCTCACTGCAACCTCCGCCTCCCGGATTCAAGCGATTCTC

>95436_95436_3_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000368848_PKN2_chr1_89206671_ENST00000316005_length(amino acids)=614AA_BP=26
MRPRGKMNGTRNWCTLVDVHPEDQAAGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKELKIKEGAENLRKVTTDKKSLA
YVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPRTPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDR
KLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQAR
FNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVAASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSK
ATSVALPGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRDW
RSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNH

--------------------------------------------------------------
>95436_95436_4_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000368848_PKN2_chr1_89206671_ENST00000370521_length(transcript)=5833nt_BP=119nt
CAGTTGGAGCCAGACAGCGGGGTGGACAAGTGGCGTGTGTGCTGCGACCCCGAGGGAAGATGAACGGGACGCGGAACTGGTGTACCCTGG
TGGACGTGCACCCAGAGGACCAGGCGGCGGGGGATTCCCGAAGTCTTCCGTTTTCTGAGAATGTGAGTGCTGTTCAAAAATTAGACTTTT
CAGATACAATGGTGCAGCAGAAATTGGATGATATCAAGGATCGAATTAAGAGAGAAATAAGGAAAGAACTGAAAATCAAAGAAGGAGCTG
AAAATCTGAGGAAAGTCACAACAGATAAAAAAAGTTTGGCTTATGTAGACAACATTTTGAAAAAATCAAATAAAAAATTAGAAGAACTAC
ATCACAAGCTGCAGGAATTAAATGCACATATTGTTGTATCAGATCCAGAAGATATTACAGATTGCCCAAGGACTCCAGATACTCCAAATA
ATGACCCTCGTTGTTCTACTAGCAACAATAGATTGAAGGCCTTACAAAAACAATTGGATATAGAACTTAAAGTAAAACAAGGTGCAGAGA
ATATGATACAGATGTATTCAAATGGATCTTCAAAGGATCGGAAACTCCATGGTACAGCTCAGCAACTGCTCCAGGACAGCAAGACAAAAA
TAGAAGTCATACGAATGCAGATTCTTCAGGCAGTCCAGACTAATGAATTGGCTTTTGATAATGCAAAACCTGTGATAAGTCCTCTTGAAC
TTCGGATGGAAGAATTAAGGCATCATTTTAGGATAGAGTTTGCAGTAGCAGAAGGTGCAAAGAATGTAATGAAATTACTTGGCTCAGGAA
AAGTAACAGACAGAAAAGCACTTTCAGAAGCTCAAGCAAGATTTAATGAATCAAGTCAGAAGTTGGACCTTTTAAAGTATTCATTAGAGC
AAAGATTAAACGAAGTCCCCAAGAATCATCCCAAAAGCAGGATTATTATTGAAGAACTTTCACTTGTTGCTGCATCACCAACACTAAGTC
CACGTCAAAGTATGATATCTACGCAAAATCAATATAGTACACTATCCAAACCAGCAGCACTAACAGGTACTTTGGAAGTTCGTCTTATGG
GCTGCCAAGATATCCTAGAGAATGTCCCTGGACGGTCAAAAGCAACATCAGTTGCACTGCCTGGTTGGAGTCCAAGTGAAACCAGATCAT
CTTTCATGAGCAGAACGAGTAAAAGTAAAAGCGGAAGTAGTCGAAATCTTCTAAAAACCGATGACTTGTCCAATGATGTCTGTGCTGTTT
TGAAGCTCGATAATACTGTGGTTGGCCAAACTAGCTGGAAACCCATTTCCAATCAGTCATGGGACCAGAAGTTTACACTGGAACTGGACA
GGTCACGTGAACTGGAAATTTCAGTTTATTGGCGTGATTGGCGGTCTCTGTGTGCTGTAAAATTTCTGAGGTTAGAAGATTTTTTAGACA
ACCAACGGCATGGCATGTGTCTCTATTTGGAACCACAGGGTACTTTATTTGCAGAGGTTACCTTTTTTAATCCAGTTATTGAAAGAAGAC
CAAAACTTCAAAGACAAAAGAAAATTTTTTCAAAGCAACAAGGCAAAACATTTCTCAGAGCTCCTCAAATGAATATTAATATTGCCACTT
GGGGAAGGCTAGTAAGAAGAGCTATTCCTACAGTAAATCATTCTGGCACCTTCAGCCCTCAAGCTCCTGTGCCTACTACAGTGCCAGTGG
TTGATGTACGCATCCCTCAACTAGCACCTCCAGCTAGTGATTCTACAGTAACCAAATTGGACTTTGATCTTGAGCCTGAACCTCCTCCAG
CCCCACCACGAGCTTCTTCTCTTGGAGAAATAGATGAATCTTCTGAATTAAGAGTTTTGGATATACCAGGACAGGATTCAGAGACTGTTT
TTGATATTCAGAATGACAGAAATAGTATACTTCCAAAATCTCAATCTGAATACAAGCCTGATACTCCTCAGTCAGGCCTAGAATATAGTG
GTATTCAAGAACTTGAGGACAGAAGATCTCAGCAAAGGTTTCAGTTTAATCTACAAGATTTCAGGTGTTGTGCTGTCTTGGGAAGAGGAC
ATTTTGGAAAGGTGCTTTTAGCTGAATATAAAAACACAAATGAGATGTTTGCTATAAAAGCCTTAAAGAAAGGAGATATTGTGGCTCGAG
ATGAAGTAGACAGCCTGATGTGTGAAAAAAGAATTTTTGAAACTGTGAATAGTGTAAGGCATCCCTTTTTGGTGAACCTTTTTGCATGTT
TCCAAACCAAAGAGCATGTTTGCTTTGTAATGGAATATGCTGCCGGTGGGGACCTAATGATGCACATTCATACTGATGTCTTTTCTGAAC
CAAGAGCTGTATTTTATGCTGCTTGTGTAGTTCTTGGGTTGCAGTATTTACATGAACACAAAATTGTTTATAGAGATTTGAAATTGGATA
ACTTATTGCTAGATACAGAGGGCTTTGTGAAAATTGCTGATTTTGGTCTTTGCAAAGAAGGAATGGGATATGGAGATAGAACAAGCACAT
TTTGTGGCACTCCTGAATTTCTTGCCCCAGAAGTATTAACAGAAACTTCTTATACAAGGGCTGTAGATTGGTGGGGCCTTGGCGTGCTTA
TATATGAAATGCTTGTTGGTGAGTCTCCCTTTCCTGGTGATGATGAAGAGGAAGTTTTTGACAGTATTGTAAATGATGAAGTAAGGTATC
CAAGGTTCTTATCTACAGAAGCCATTTCTATAATGAGAAGGCTGTTAAGAAGAAATCCTGAACGGCGCCTTGGGGCTAGCGAGAAAGATG
CAGAGGATGTAAAAAAGCACCCATTTTTCCGGCTAATTGATTGGAGCGCTCTGATGGACAAAAAAGTAAAGCCACCATTTATACCTACCA
TAAGAGGACGAGAAGATGTTAGTAATTTTGATGATGAATTTACCTCAGAAGCACCTATTCTGACTCCACCTCGAGAACCAAGGATACTTT
CGGAAGAGGAGCAGGAAATGTTCAGAGATTTTGACTACATTGCTGATTGGTGTTAAGTTGCTAGACACTGCGAAACCAAGCTGACTCACA
AGAAGACCTCTTAAAAATAGCAACCCTTCATTTGCTCTCTGTGCCACCAATAGCTTCTGAGTTTTTTGTTGTTGTTGTTTTTATTGAAAC
ACGTGAAGATTTGTTTAAAAGTACCATTCTAATACTTCTTCAAAAGTGGCTCCTCATTGTACTTCAGCGTAAATATGAGCACTGGAAACA
GTTTCATGGAGTTTAAGTTGAGTGAACATCGGCCATGAAAATCCATCACGAATACTTTTGGATCAATAGTCTATTTTTAAAAAGAAAGAA
AAAAACCACTTTTTTATAGTCCCTAGCTTTGCCATATGCCCGCCTTAAGTGGAAGGAAAGTTAATCACTTAACTATGTTTTATAAAAAGA
AAAAAGGGCTTGGAATGCTATTACTGTTCACACAAAGTATGATTCTGTTTGAATAAGGCAAATGCTCCTTTTTTTAAAAAAAAAGACATT
ACTGTAATATCAAAAACCGTGGCAGTTTGTATACAACTCGGGGCTTGATTTTTTTTAAAAAAACAGAATGAATTGATGTCTTATTTTATA
AATGTTCTATATTTATTAGGAGAAAACTTTATATTGCCTTTTTTATCAATCATGTAACAGGCTTATAGCTTTCCAACAGAGCTGCTTGCC
AAACAATTTTTTTTGTTTATTAAACAGTGCTGAAACAAACAGGATCAGCATTTACTTAAGATGTTAAGAATGAGGACTTTTAATCAGCCG
AACCAAGATATTGTTACCTGTATGCATTCCCAAAGTCTAGATGCTCAGTATGTTCAGTCATATCTTTCAGAATCAGTGAACCGATTACCC
TTTTTTTGGTATTCACTCTACATCTGCCAACCTAGTTCACCTTGGTTTTGTGTCTGCTGTAGAAGGGAACCATAACTTGGTTAAACCGTA
GGGATTATCATTGTATACATGCTGTGAACATGTATATGTGCAAGTTTTAATGTATTCTATGTTGTAGGCTTATTATTTAATTTTACCACT
TCATCACTTTTGTACAGTGGCCAAGCAGACACCTCAAACTCCAGCATTTACATTAAGTGCATTTGTACATTTTAGGCCACTGGATCCAGA
TTTTATATTGGCAGTTATTGAGGGCAAAAGCAATATATTGTAACAGAATGTATAAATATTTTTGATAAAACAGTCTATATTTTATTAAAA
AATGAATTATAACACTAAAGCTGTACCTCAAAAGTCTCAAAAATAATTTGATGAAATATTTTATACAACTCTTCAAAGGATCCGTCTGTG
GCTTTTTATACTCTTTTAGGGTTGTCTTTTTACAAACCATGACTTTCCACTTGCCTGTAGTTTTTTGTTTGTTTTGGTTTGGTTTGATTT
TATATTTTTTTCTCCTAATCTATGACTTTATTGTTTTTTCTTAGTTTAGTAATAGCATCTTTGATCCTGTGCTTAGCATGTTAGGGTCAT
TATACCTCAGGAATAGCAAGCTGTTAAGTAACCATACTGAATTAACTATTTAATTACAGTGAGCTCATCTCTTAAAAATTGTTCAGGTGT
AAATCTTATGAGAAACATGAAAAAGCACACTGATTTATGGAGAGTTGAGCTAAAAACATTTATAAATATTTGCTGGGATGTTTTAGCATC
TTTTCATTGTACTCTGAGAACAATTAAAATTGTCCAGAGATCATTTATATTACCTTCCAAATTGTTTATTACCCAAGATCCTTTGGGAGA
AAATCTTATAGAATGGGGGAACAATATGTGGTTTAAAGTTATTTTAAAATGCCAGTTAATTTCCTCGGCAAAGGACAATAGAGGAACTTA
GCTTAATTGTCTGGCTTTAATTTAAACTGTGTTAATACAACATTAAAATAAAACACTAAATACTTTTGAGGTACAGTCTGCTCACTTTTT
TGGTTCTCAAATAGCAAAGAAAGTAATGTCTAAAATAGGCTCTTAGCATTAAAAACTGACAGCATTTCGTAACTACACAGTGTACAGAAT
TTTTTTTTAATTGAAGTCAATCACTAAAAAAATTAGAAGGCAGGGTCTATTTACACAATTAAGCTGAAGAAAGCACTAATTTTTTGTAGT
TTAAAATATATATATATTTTAGTCAGATTTAAAATTTTAAGCTTTATAGAGTGTAAATATATTTTGCTATTACTGTATGTGTATGTGACT
GCTCAAGCACTTTGTAAAGAAATTAGGATATTTTAGAATGGTACACTATGCATTCAAATGAAATGTGCCTTTCACTATGTCATTCTAAGA
AAACAAGTGTTTTTTGCAGTCATAAATTATCACAAATGCACAAATTAAAGTCTATATAGATTGAAATTTGTAACTTTGGTTTTAAGTATT
CTTTCCTTTTAGAAACTTCCTAATGATTAAAATATACTTTAACTTTTCTGTGTTCAAAATCTCAAAGACTAATTAACTTTAATAAACATT
CTTGCAAGTACTTTTTGTCCTAGTGAAGGCTTAAAACCATGAACATTCAGAGCAAACTGTCCACTTCATTGGGAATAATGGGAAAAGTTT
GTATTCTGCTCCTGTAAGGTCAGTAGCATCTTTTATTTGAAGCATATTTATGGACTGCTTACTGTGTATAGATACTGAGAATAGGAAGTT
TTTTTTTTTAAAGCAACAAAATGTTGATGAATGAAGAACAGCCTGTTTTAATTAAGATGCAAGCACCAGTATTGTATGTACTTTTCTCTT

>95436_95436_4_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000368848_PKN2_chr1_89206671_ENST00000370521_length(amino acids)=994AA_BP=26
MRPRGKMNGTRNWCTLVDVHPEDQAAGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKELKIKEGAENLRKVTTDKKSLA
YVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPRTPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDR
KLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQAR
FNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVAASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSK
ATSVALPGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRDW
RSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNH
SGTFSPQAPVPTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPGQDSETVFDIQNDRNSILPKS
QSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFE
TVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIAD
FGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR
LLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYI

--------------------------------------------------------------
>95436_95436_5_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000368849_PKN2_chr1_89206671_ENST00000316005_length(transcript)=2347nt_BP=122nt
GCCCAGTTGGAGCCAGACAGCGGGGTGGACAAGTGGCGTGTGTGCTGCGACCCCGAGGGAAGATGAACGGGACGCGGAACTGGTGTACCC
TGGTGGACGTGCACCCAGAGGACCAGGCGGCGGGGGATTCCCGAAGTCTTCCGTTTTCTGAGAATGTGAGTGCTGTTCAAAAATTAGACT
TTTCAGATACAATGGTGCAGCAGAAATTGGATGATATCAAGGATCGAATTAAGAGAGAAATAAGGAAAGAACTGAAAATCAAAGAAGGAG
CTGAAAATCTGAGGAAAGTCACAACAGATAAAAAAAGTTTGGCTTATGTAGACAACATTTTGAAAAAATCAAATAAAAAATTAGAAGAAC
TACATCACAAGCTGCAGGAATTAAATGCACATATTGTTGTATCAGATCCAGAAGATATTACAGATTGCCCAAGGACTCCAGATACTCCAA
ATAATGACCCTCGTTGTTCTACTAGCAACAATAGATTGAAGGCCTTACAAAAACAATTGGATATAGAACTTAAAGTAAAACAAGGTGCAG
AGAATATGATACAGATGTATTCAAATGGATCTTCAAAGGATCGGAAACTCCATGGTACAGCTCAGCAACTGCTCCAGGACAGCAAGACAA
AAATAGAAGTCATACGAATGCAGATTCTTCAGGCAGTCCAGACTAATGAATTGGCTTTTGATAATGCAAAACCTGTGATAAGTCCTCTTG
AACTTCGGATGGAAGAATTAAGGCATCATTTTAGGATAGAGTTTGCAGTAGCAGAAGGTGCAAAGAATGTAATGAAATTACTTGGCTCAG
GAAAAGTAACAGACAGAAAAGCACTTTCAGAAGCTCAAGCAAGATTTAATGAATCAAGTCAGAAGTTGGACCTTTTAAAGTATTCATTAG
AGCAAAGATTAAACGAAGTCCCCAAGAATCATCCCAAAAGCAGGATTATTATTGAAGAACTTTCACTTGTTGCTGCATCACCAACACTAA
GTCCACGTCAAAGTATGATATCTACGCAAAATCAATATAGTACACTATCCAAACCAGCAGCACTAACAGGTACTTTGGAAGTTCGTCTTA
TGGGCTGCCAAGATATCCTAGAGAATGTCCCTGGACGGTCAAAAGCAACATCAGTTGCACTGCCTGGTTGGAGTCCAAGTGAAACCAGAT
CATCTTTCATGAGCAGAACGAGTAAAAGTAAAAGCGGAAGTAGTCGAAATCTTCTAAAAACCGATGACTTGTCCAATGATGTCTGTGCTG
TTTTGAAGCTCGATAATACTGTGGTTGGCCAAACTAGCTGGAAACCCATTTCCAATCAGTCATGGGACCAGAAGTTTACACTGGAACTGG
ACAGGTCACGTGAACTGGAAATTTCAGTTTATTGGCGTGATTGGCGGTCTCTGTGTGCTGTAAAATTTCTGAGGTTAGAAGATTTTTTAG
ACAACCAACGGCATGGCATGTGTCTCTATTTGGAACCACAGGGTACTTTATTTGCAGAGGTTACCTTTTTTAATCCAGTTATTGAAAGAA
GACCAAAACTTCAAAGACAAAAGAAAATTTTTTCAAAGCAACAAGGCAAAACATTTCTCAGAGCTCCTCAAATGAATATTAATATTGCCA
CTTGGGGAAGGCTAGTAAGAAGAGCTATTCCTACAGTAAATCATTCTGGCACCTTCAGCCCTCAAGCTCCTGTGCCTACTACAGTGCCAG
TGGTTGATGTACGCATCCCTCAACTAGCACCTCCAGCTAGGTATGTGTCTGAGATTTTAAGCATCTCTTATACAAAGTTATTGGGACATT
CTTACGTACTGATTATAGCAGGTGTACTGAGTCTTGCTTTTTTCCCAAGTAGTATTTTGAAAGTAGTGTTCTGTTTACTTAAAAAGTAAA
TTGTTTGCTTTAATTTTAAAGCTGTTTAAAATACAGACTTTCTATTACTGTTTTGGTGAGTTACTTTATCTTCTATAAGTGATTCTACAG
TAACCAAATTGGACTTTGATCTTGAGCCTGAACCTCCTCCAGCCCCACCACGAGCTTCTTCTCTTGGAGAAATAGATGAATCTTCTGAAT
TAAGAGTTTTGGATATACCAGGACAGGCAAGCCATTTTAAACCTTGCATAATTCCTCTTCACTGAATGAATTAGCAATAAAAGCATCATA
GTGAATAAGGCGTGTCTTTCCATTTAAAATTGCCACTGAACTGTGAATTTATGGTTTTTTGTTTGTTTTTTGTTTTTGTTTTTGTTTTTT
GAGACAGAGTTTCACTCTTGTTACCCAGGCTGGAGTGCAATGGCATGATCTCGGCTCACTGCAACCTCCGCCTCCCGGATTCAAGCGATT

>95436_95436_5_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000368849_PKN2_chr1_89206671_ENST00000316005_length(amino acids)=614AA_BP=26
MRPRGKMNGTRNWCTLVDVHPEDQAAGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKELKIKEGAENLRKVTTDKKSLA
YVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPRTPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDR
KLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQAR
FNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVAASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSK
ATSVALPGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRDW
RSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNH

--------------------------------------------------------------
>95436_95436_6_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000368849_PKN2_chr1_89206671_ENST00000370521_length(transcript)=5836nt_BP=122nt
GCCCAGTTGGAGCCAGACAGCGGGGTGGACAAGTGGCGTGTGTGCTGCGACCCCGAGGGAAGATGAACGGGACGCGGAACTGGTGTACCC
TGGTGGACGTGCACCCAGAGGACCAGGCGGCGGGGGATTCCCGAAGTCTTCCGTTTTCTGAGAATGTGAGTGCTGTTCAAAAATTAGACT
TTTCAGATACAATGGTGCAGCAGAAATTGGATGATATCAAGGATCGAATTAAGAGAGAAATAAGGAAAGAACTGAAAATCAAAGAAGGAG
CTGAAAATCTGAGGAAAGTCACAACAGATAAAAAAAGTTTGGCTTATGTAGACAACATTTTGAAAAAATCAAATAAAAAATTAGAAGAAC
TACATCACAAGCTGCAGGAATTAAATGCACATATTGTTGTATCAGATCCAGAAGATATTACAGATTGCCCAAGGACTCCAGATACTCCAA
ATAATGACCCTCGTTGTTCTACTAGCAACAATAGATTGAAGGCCTTACAAAAACAATTGGATATAGAACTTAAAGTAAAACAAGGTGCAG
AGAATATGATACAGATGTATTCAAATGGATCTTCAAAGGATCGGAAACTCCATGGTACAGCTCAGCAACTGCTCCAGGACAGCAAGACAA
AAATAGAAGTCATACGAATGCAGATTCTTCAGGCAGTCCAGACTAATGAATTGGCTTTTGATAATGCAAAACCTGTGATAAGTCCTCTTG
AACTTCGGATGGAAGAATTAAGGCATCATTTTAGGATAGAGTTTGCAGTAGCAGAAGGTGCAAAGAATGTAATGAAATTACTTGGCTCAG
GAAAAGTAACAGACAGAAAAGCACTTTCAGAAGCTCAAGCAAGATTTAATGAATCAAGTCAGAAGTTGGACCTTTTAAAGTATTCATTAG
AGCAAAGATTAAACGAAGTCCCCAAGAATCATCCCAAAAGCAGGATTATTATTGAAGAACTTTCACTTGTTGCTGCATCACCAACACTAA
GTCCACGTCAAAGTATGATATCTACGCAAAATCAATATAGTACACTATCCAAACCAGCAGCACTAACAGGTACTTTGGAAGTTCGTCTTA
TGGGCTGCCAAGATATCCTAGAGAATGTCCCTGGACGGTCAAAAGCAACATCAGTTGCACTGCCTGGTTGGAGTCCAAGTGAAACCAGAT
CATCTTTCATGAGCAGAACGAGTAAAAGTAAAAGCGGAAGTAGTCGAAATCTTCTAAAAACCGATGACTTGTCCAATGATGTCTGTGCTG
TTTTGAAGCTCGATAATACTGTGGTTGGCCAAACTAGCTGGAAACCCATTTCCAATCAGTCATGGGACCAGAAGTTTACACTGGAACTGG
ACAGGTCACGTGAACTGGAAATTTCAGTTTATTGGCGTGATTGGCGGTCTCTGTGTGCTGTAAAATTTCTGAGGTTAGAAGATTTTTTAG
ACAACCAACGGCATGGCATGTGTCTCTATTTGGAACCACAGGGTACTTTATTTGCAGAGGTTACCTTTTTTAATCCAGTTATTGAAAGAA
GACCAAAACTTCAAAGACAAAAGAAAATTTTTTCAAAGCAACAAGGCAAAACATTTCTCAGAGCTCCTCAAATGAATATTAATATTGCCA
CTTGGGGAAGGCTAGTAAGAAGAGCTATTCCTACAGTAAATCATTCTGGCACCTTCAGCCCTCAAGCTCCTGTGCCTACTACAGTGCCAG
TGGTTGATGTACGCATCCCTCAACTAGCACCTCCAGCTAGTGATTCTACAGTAACCAAATTGGACTTTGATCTTGAGCCTGAACCTCCTC
CAGCCCCACCACGAGCTTCTTCTCTTGGAGAAATAGATGAATCTTCTGAATTAAGAGTTTTGGATATACCAGGACAGGATTCAGAGACTG
TTTTTGATATTCAGAATGACAGAAATAGTATACTTCCAAAATCTCAATCTGAATACAAGCCTGATACTCCTCAGTCAGGCCTAGAATATA
GTGGTATTCAAGAACTTGAGGACAGAAGATCTCAGCAAAGGTTTCAGTTTAATCTACAAGATTTCAGGTGTTGTGCTGTCTTGGGAAGAG
GACATTTTGGAAAGGTGCTTTTAGCTGAATATAAAAACACAAATGAGATGTTTGCTATAAAAGCCTTAAAGAAAGGAGATATTGTGGCTC
GAGATGAAGTAGACAGCCTGATGTGTGAAAAAAGAATTTTTGAAACTGTGAATAGTGTAAGGCATCCCTTTTTGGTGAACCTTTTTGCAT
GTTTCCAAACCAAAGAGCATGTTTGCTTTGTAATGGAATATGCTGCCGGTGGGGACCTAATGATGCACATTCATACTGATGTCTTTTCTG
AACCAAGAGCTGTATTTTATGCTGCTTGTGTAGTTCTTGGGTTGCAGTATTTACATGAACACAAAATTGTTTATAGAGATTTGAAATTGG
ATAACTTATTGCTAGATACAGAGGGCTTTGTGAAAATTGCTGATTTTGGTCTTTGCAAAGAAGGAATGGGATATGGAGATAGAACAAGCA
CATTTTGTGGCACTCCTGAATTTCTTGCCCCAGAAGTATTAACAGAAACTTCTTATACAAGGGCTGTAGATTGGTGGGGCCTTGGCGTGC
TTATATATGAAATGCTTGTTGGTGAGTCTCCCTTTCCTGGTGATGATGAAGAGGAAGTTTTTGACAGTATTGTAAATGATGAAGTAAGGT
ATCCAAGGTTCTTATCTACAGAAGCCATTTCTATAATGAGAAGGCTGTTAAGAAGAAATCCTGAACGGCGCCTTGGGGCTAGCGAGAAAG
ATGCAGAGGATGTAAAAAAGCACCCATTTTTCCGGCTAATTGATTGGAGCGCTCTGATGGACAAAAAAGTAAAGCCACCATTTATACCTA
CCATAAGAGGACGAGAAGATGTTAGTAATTTTGATGATGAATTTACCTCAGAAGCACCTATTCTGACTCCACCTCGAGAACCAAGGATAC
TTTCGGAAGAGGAGCAGGAAATGTTCAGAGATTTTGACTACATTGCTGATTGGTGTTAAGTTGCTAGACACTGCGAAACCAAGCTGACTC
ACAAGAAGACCTCTTAAAAATAGCAACCCTTCATTTGCTCTCTGTGCCACCAATAGCTTCTGAGTTTTTTGTTGTTGTTGTTTTTATTGA
AACACGTGAAGATTTGTTTAAAAGTACCATTCTAATACTTCTTCAAAAGTGGCTCCTCATTGTACTTCAGCGTAAATATGAGCACTGGAA
ACAGTTTCATGGAGTTTAAGTTGAGTGAACATCGGCCATGAAAATCCATCACGAATACTTTTGGATCAATAGTCTATTTTTAAAAAGAAA
GAAAAAAACCACTTTTTTATAGTCCCTAGCTTTGCCATATGCCCGCCTTAAGTGGAAGGAAAGTTAATCACTTAACTATGTTTTATAAAA
AGAAAAAAGGGCTTGGAATGCTATTACTGTTCACACAAAGTATGATTCTGTTTGAATAAGGCAAATGCTCCTTTTTTTAAAAAAAAAGAC
ATTACTGTAATATCAAAAACCGTGGCAGTTTGTATACAACTCGGGGCTTGATTTTTTTTAAAAAAACAGAATGAATTGATGTCTTATTTT
ATAAATGTTCTATATTTATTAGGAGAAAACTTTATATTGCCTTTTTTATCAATCATGTAACAGGCTTATAGCTTTCCAACAGAGCTGCTT
GCCAAACAATTTTTTTTGTTTATTAAACAGTGCTGAAACAAACAGGATCAGCATTTACTTAAGATGTTAAGAATGAGGACTTTTAATCAG
CCGAACCAAGATATTGTTACCTGTATGCATTCCCAAAGTCTAGATGCTCAGTATGTTCAGTCATATCTTTCAGAATCAGTGAACCGATTA
CCCTTTTTTTGGTATTCACTCTACATCTGCCAACCTAGTTCACCTTGGTTTTGTGTCTGCTGTAGAAGGGAACCATAACTTGGTTAAACC
GTAGGGATTATCATTGTATACATGCTGTGAACATGTATATGTGCAAGTTTTAATGTATTCTATGTTGTAGGCTTATTATTTAATTTTACC
ACTTCATCACTTTTGTACAGTGGCCAAGCAGACACCTCAAACTCCAGCATTTACATTAAGTGCATTTGTACATTTTAGGCCACTGGATCC
AGATTTTATATTGGCAGTTATTGAGGGCAAAAGCAATATATTGTAACAGAATGTATAAATATTTTTGATAAAACAGTCTATATTTTATTA
AAAAATGAATTATAACACTAAAGCTGTACCTCAAAAGTCTCAAAAATAATTTGATGAAATATTTTATACAACTCTTCAAAGGATCCGTCT
GTGGCTTTTTATACTCTTTTAGGGTTGTCTTTTTACAAACCATGACTTTCCACTTGCCTGTAGTTTTTTGTTTGTTTTGGTTTGGTTTGA
TTTTATATTTTTTTCTCCTAATCTATGACTTTATTGTTTTTTCTTAGTTTAGTAATAGCATCTTTGATCCTGTGCTTAGCATGTTAGGGT
CATTATACCTCAGGAATAGCAAGCTGTTAAGTAACCATACTGAATTAACTATTTAATTACAGTGAGCTCATCTCTTAAAAATTGTTCAGG
TGTAAATCTTATGAGAAACATGAAAAAGCACACTGATTTATGGAGAGTTGAGCTAAAAACATTTATAAATATTTGCTGGGATGTTTTAGC
ATCTTTTCATTGTACTCTGAGAACAATTAAAATTGTCCAGAGATCATTTATATTACCTTCCAAATTGTTTATTACCCAAGATCCTTTGGG
AGAAAATCTTATAGAATGGGGGAACAATATGTGGTTTAAAGTTATTTTAAAATGCCAGTTAATTTCCTCGGCAAAGGACAATAGAGGAAC
TTAGCTTAATTGTCTGGCTTTAATTTAAACTGTGTTAATACAACATTAAAATAAAACACTAAATACTTTTGAGGTACAGTCTGCTCACTT
TTTTGGTTCTCAAATAGCAAAGAAAGTAATGTCTAAAATAGGCTCTTAGCATTAAAAACTGACAGCATTTCGTAACTACACAGTGTACAG
AATTTTTTTTTAATTGAAGTCAATCACTAAAAAAATTAGAAGGCAGGGTCTATTTACACAATTAAGCTGAAGAAAGCACTAATTTTTTGT
AGTTTAAAATATATATATATTTTAGTCAGATTTAAAATTTTAAGCTTTATAGAGTGTAAATATATTTTGCTATTACTGTATGTGTATGTG
ACTGCTCAAGCACTTTGTAAAGAAATTAGGATATTTTAGAATGGTACACTATGCATTCAAATGAAATGTGCCTTTCACTATGTCATTCTA
AGAAAACAAGTGTTTTTTGCAGTCATAAATTATCACAAATGCACAAATTAAAGTCTATATAGATTGAAATTTGTAACTTTGGTTTTAAGT
ATTCTTTCCTTTTAGAAACTTCCTAATGATTAAAATATACTTTAACTTTTCTGTGTTCAAAATCTCAAAGACTAATTAACTTTAATAAAC
ATTCTTGCAAGTACTTTTTGTCCTAGTGAAGGCTTAAAACCATGAACATTCAGAGCAAACTGTCCACTTCATTGGGAATAATGGGAAAAG
TTTGTATTCTGCTCCTGTAAGGTCAGTAGCATCTTTTATTTGAAGCATATTTATGGACTGCTTACTGTGTATAGATACTGAGAATAGGAA
GTTTTTTTTTTTAAAGCAACAAAATGTTGATGAATGAAGAACAGCCTGTTTTAATTAAGATGCAAGCACCAGTATTGTATGTACTTTTCT

>95436_95436_6_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000368849_PKN2_chr1_89206671_ENST00000370521_length(amino acids)=994AA_BP=26
MRPRGKMNGTRNWCTLVDVHPEDQAAGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKELKIKEGAENLRKVTTDKKSLA
YVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPRTPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDR
KLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQAR
FNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVAASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSK
ATSVALPGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRDW
RSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNH
SGTFSPQAPVPTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPGQDSETVFDIQNDRNSILPKS
QSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFE
TVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIAD
FGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR
LLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYI

--------------------------------------------------------------
>95436_95436_7_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000392712_PKN2_chr1_89206671_ENST00000316005_length(transcript)=2347nt_BP=122nt
GCCCAGTTGGAGCCAGACAGCGGGGTGGACAAGTGGCGTGTGTGCTGCGACCCCGAGGGAAGATGAACGGGACGCGGAACTGGTGTACCC
TGGTGGACGTGCACCCAGAGGACCAGGCGGCGGGGGATTCCCGAAGTCTTCCGTTTTCTGAGAATGTGAGTGCTGTTCAAAAATTAGACT
TTTCAGATACAATGGTGCAGCAGAAATTGGATGATATCAAGGATCGAATTAAGAGAGAAATAAGGAAAGAACTGAAAATCAAAGAAGGAG
CTGAAAATCTGAGGAAAGTCACAACAGATAAAAAAAGTTTGGCTTATGTAGACAACATTTTGAAAAAATCAAATAAAAAATTAGAAGAAC
TACATCACAAGCTGCAGGAATTAAATGCACATATTGTTGTATCAGATCCAGAAGATATTACAGATTGCCCAAGGACTCCAGATACTCCAA
ATAATGACCCTCGTTGTTCTACTAGCAACAATAGATTGAAGGCCTTACAAAAACAATTGGATATAGAACTTAAAGTAAAACAAGGTGCAG
AGAATATGATACAGATGTATTCAAATGGATCTTCAAAGGATCGGAAACTCCATGGTACAGCTCAGCAACTGCTCCAGGACAGCAAGACAA
AAATAGAAGTCATACGAATGCAGATTCTTCAGGCAGTCCAGACTAATGAATTGGCTTTTGATAATGCAAAACCTGTGATAAGTCCTCTTG
AACTTCGGATGGAAGAATTAAGGCATCATTTTAGGATAGAGTTTGCAGTAGCAGAAGGTGCAAAGAATGTAATGAAATTACTTGGCTCAG
GAAAAGTAACAGACAGAAAAGCACTTTCAGAAGCTCAAGCAAGATTTAATGAATCAAGTCAGAAGTTGGACCTTTTAAAGTATTCATTAG
AGCAAAGATTAAACGAAGTCCCCAAGAATCATCCCAAAAGCAGGATTATTATTGAAGAACTTTCACTTGTTGCTGCATCACCAACACTAA
GTCCACGTCAAAGTATGATATCTACGCAAAATCAATATAGTACACTATCCAAACCAGCAGCACTAACAGGTACTTTGGAAGTTCGTCTTA
TGGGCTGCCAAGATATCCTAGAGAATGTCCCTGGACGGTCAAAAGCAACATCAGTTGCACTGCCTGGTTGGAGTCCAAGTGAAACCAGAT
CATCTTTCATGAGCAGAACGAGTAAAAGTAAAAGCGGAAGTAGTCGAAATCTTCTAAAAACCGATGACTTGTCCAATGATGTCTGTGCTG
TTTTGAAGCTCGATAATACTGTGGTTGGCCAAACTAGCTGGAAACCCATTTCCAATCAGTCATGGGACCAGAAGTTTACACTGGAACTGG
ACAGGTCACGTGAACTGGAAATTTCAGTTTATTGGCGTGATTGGCGGTCTCTGTGTGCTGTAAAATTTCTGAGGTTAGAAGATTTTTTAG
ACAACCAACGGCATGGCATGTGTCTCTATTTGGAACCACAGGGTACTTTATTTGCAGAGGTTACCTTTTTTAATCCAGTTATTGAAAGAA
GACCAAAACTTCAAAGACAAAAGAAAATTTTTTCAAAGCAACAAGGCAAAACATTTCTCAGAGCTCCTCAAATGAATATTAATATTGCCA
CTTGGGGAAGGCTAGTAAGAAGAGCTATTCCTACAGTAAATCATTCTGGCACCTTCAGCCCTCAAGCTCCTGTGCCTACTACAGTGCCAG
TGGTTGATGTACGCATCCCTCAACTAGCACCTCCAGCTAGGTATGTGTCTGAGATTTTAAGCATCTCTTATACAAAGTTATTGGGACATT
CTTACGTACTGATTATAGCAGGTGTACTGAGTCTTGCTTTTTTCCCAAGTAGTATTTTGAAAGTAGTGTTCTGTTTACTTAAAAAGTAAA
TTGTTTGCTTTAATTTTAAAGCTGTTTAAAATACAGACTTTCTATTACTGTTTTGGTGAGTTACTTTATCTTCTATAAGTGATTCTACAG
TAACCAAATTGGACTTTGATCTTGAGCCTGAACCTCCTCCAGCCCCACCACGAGCTTCTTCTCTTGGAGAAATAGATGAATCTTCTGAAT
TAAGAGTTTTGGATATACCAGGACAGGCAAGCCATTTTAAACCTTGCATAATTCCTCTTCACTGAATGAATTAGCAATAAAAGCATCATA
GTGAATAAGGCGTGTCTTTCCATTTAAAATTGCCACTGAACTGTGAATTTATGGTTTTTTGTTTGTTTTTTGTTTTTGTTTTTGTTTTTT
GAGACAGAGTTTCACTCTTGTTACCCAGGCTGGAGTGCAATGGCATGATCTCGGCTCACTGCAACCTCCGCCTCCCGGATTCAAGCGATT

>95436_95436_7_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000392712_PKN2_chr1_89206671_ENST00000316005_length(amino acids)=614AA_BP=26
MRPRGKMNGTRNWCTLVDVHPEDQAAGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKELKIKEGAENLRKVTTDKKSLA
YVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPRTPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDR
KLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQAR
FNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVAASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSK
ATSVALPGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRDW
RSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNH

--------------------------------------------------------------
>95436_95436_8_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000392712_PKN2_chr1_89206671_ENST00000370521_length(transcript)=5836nt_BP=122nt
GCCCAGTTGGAGCCAGACAGCGGGGTGGACAAGTGGCGTGTGTGCTGCGACCCCGAGGGAAGATGAACGGGACGCGGAACTGGTGTACCC
TGGTGGACGTGCACCCAGAGGACCAGGCGGCGGGGGATTCCCGAAGTCTTCCGTTTTCTGAGAATGTGAGTGCTGTTCAAAAATTAGACT
TTTCAGATACAATGGTGCAGCAGAAATTGGATGATATCAAGGATCGAATTAAGAGAGAAATAAGGAAAGAACTGAAAATCAAAGAAGGAG
CTGAAAATCTGAGGAAAGTCACAACAGATAAAAAAAGTTTGGCTTATGTAGACAACATTTTGAAAAAATCAAATAAAAAATTAGAAGAAC
TACATCACAAGCTGCAGGAATTAAATGCACATATTGTTGTATCAGATCCAGAAGATATTACAGATTGCCCAAGGACTCCAGATACTCCAA
ATAATGACCCTCGTTGTTCTACTAGCAACAATAGATTGAAGGCCTTACAAAAACAATTGGATATAGAACTTAAAGTAAAACAAGGTGCAG
AGAATATGATACAGATGTATTCAAATGGATCTTCAAAGGATCGGAAACTCCATGGTACAGCTCAGCAACTGCTCCAGGACAGCAAGACAA
AAATAGAAGTCATACGAATGCAGATTCTTCAGGCAGTCCAGACTAATGAATTGGCTTTTGATAATGCAAAACCTGTGATAAGTCCTCTTG
AACTTCGGATGGAAGAATTAAGGCATCATTTTAGGATAGAGTTTGCAGTAGCAGAAGGTGCAAAGAATGTAATGAAATTACTTGGCTCAG
GAAAAGTAACAGACAGAAAAGCACTTTCAGAAGCTCAAGCAAGATTTAATGAATCAAGTCAGAAGTTGGACCTTTTAAAGTATTCATTAG
AGCAAAGATTAAACGAAGTCCCCAAGAATCATCCCAAAAGCAGGATTATTATTGAAGAACTTTCACTTGTTGCTGCATCACCAACACTAA
GTCCACGTCAAAGTATGATATCTACGCAAAATCAATATAGTACACTATCCAAACCAGCAGCACTAACAGGTACTTTGGAAGTTCGTCTTA
TGGGCTGCCAAGATATCCTAGAGAATGTCCCTGGACGGTCAAAAGCAACATCAGTTGCACTGCCTGGTTGGAGTCCAAGTGAAACCAGAT
CATCTTTCATGAGCAGAACGAGTAAAAGTAAAAGCGGAAGTAGTCGAAATCTTCTAAAAACCGATGACTTGTCCAATGATGTCTGTGCTG
TTTTGAAGCTCGATAATACTGTGGTTGGCCAAACTAGCTGGAAACCCATTTCCAATCAGTCATGGGACCAGAAGTTTACACTGGAACTGG
ACAGGTCACGTGAACTGGAAATTTCAGTTTATTGGCGTGATTGGCGGTCTCTGTGTGCTGTAAAATTTCTGAGGTTAGAAGATTTTTTAG
ACAACCAACGGCATGGCATGTGTCTCTATTTGGAACCACAGGGTACTTTATTTGCAGAGGTTACCTTTTTTAATCCAGTTATTGAAAGAA
GACCAAAACTTCAAAGACAAAAGAAAATTTTTTCAAAGCAACAAGGCAAAACATTTCTCAGAGCTCCTCAAATGAATATTAATATTGCCA
CTTGGGGAAGGCTAGTAAGAAGAGCTATTCCTACAGTAAATCATTCTGGCACCTTCAGCCCTCAAGCTCCTGTGCCTACTACAGTGCCAG
TGGTTGATGTACGCATCCCTCAACTAGCACCTCCAGCTAGTGATTCTACAGTAACCAAATTGGACTTTGATCTTGAGCCTGAACCTCCTC
CAGCCCCACCACGAGCTTCTTCTCTTGGAGAAATAGATGAATCTTCTGAATTAAGAGTTTTGGATATACCAGGACAGGATTCAGAGACTG
TTTTTGATATTCAGAATGACAGAAATAGTATACTTCCAAAATCTCAATCTGAATACAAGCCTGATACTCCTCAGTCAGGCCTAGAATATA
GTGGTATTCAAGAACTTGAGGACAGAAGATCTCAGCAAAGGTTTCAGTTTAATCTACAAGATTTCAGGTGTTGTGCTGTCTTGGGAAGAG
GACATTTTGGAAAGGTGCTTTTAGCTGAATATAAAAACACAAATGAGATGTTTGCTATAAAAGCCTTAAAGAAAGGAGATATTGTGGCTC
GAGATGAAGTAGACAGCCTGATGTGTGAAAAAAGAATTTTTGAAACTGTGAATAGTGTAAGGCATCCCTTTTTGGTGAACCTTTTTGCAT
GTTTCCAAACCAAAGAGCATGTTTGCTTTGTAATGGAATATGCTGCCGGTGGGGACCTAATGATGCACATTCATACTGATGTCTTTTCTG
AACCAAGAGCTGTATTTTATGCTGCTTGTGTAGTTCTTGGGTTGCAGTATTTACATGAACACAAAATTGTTTATAGAGATTTGAAATTGG
ATAACTTATTGCTAGATACAGAGGGCTTTGTGAAAATTGCTGATTTTGGTCTTTGCAAAGAAGGAATGGGATATGGAGATAGAACAAGCA
CATTTTGTGGCACTCCTGAATTTCTTGCCCCAGAAGTATTAACAGAAACTTCTTATACAAGGGCTGTAGATTGGTGGGGCCTTGGCGTGC
TTATATATGAAATGCTTGTTGGTGAGTCTCCCTTTCCTGGTGATGATGAAGAGGAAGTTTTTGACAGTATTGTAAATGATGAAGTAAGGT
ATCCAAGGTTCTTATCTACAGAAGCCATTTCTATAATGAGAAGGCTGTTAAGAAGAAATCCTGAACGGCGCCTTGGGGCTAGCGAGAAAG
ATGCAGAGGATGTAAAAAAGCACCCATTTTTCCGGCTAATTGATTGGAGCGCTCTGATGGACAAAAAAGTAAAGCCACCATTTATACCTA
CCATAAGAGGACGAGAAGATGTTAGTAATTTTGATGATGAATTTACCTCAGAAGCACCTATTCTGACTCCACCTCGAGAACCAAGGATAC
TTTCGGAAGAGGAGCAGGAAATGTTCAGAGATTTTGACTACATTGCTGATTGGTGTTAAGTTGCTAGACACTGCGAAACCAAGCTGACTC
ACAAGAAGACCTCTTAAAAATAGCAACCCTTCATTTGCTCTCTGTGCCACCAATAGCTTCTGAGTTTTTTGTTGTTGTTGTTTTTATTGA
AACACGTGAAGATTTGTTTAAAAGTACCATTCTAATACTTCTTCAAAAGTGGCTCCTCATTGTACTTCAGCGTAAATATGAGCACTGGAA
ACAGTTTCATGGAGTTTAAGTTGAGTGAACATCGGCCATGAAAATCCATCACGAATACTTTTGGATCAATAGTCTATTTTTAAAAAGAAA
GAAAAAAACCACTTTTTTATAGTCCCTAGCTTTGCCATATGCCCGCCTTAAGTGGAAGGAAAGTTAATCACTTAACTATGTTTTATAAAA
AGAAAAAAGGGCTTGGAATGCTATTACTGTTCACACAAAGTATGATTCTGTTTGAATAAGGCAAATGCTCCTTTTTTTAAAAAAAAAGAC
ATTACTGTAATATCAAAAACCGTGGCAGTTTGTATACAACTCGGGGCTTGATTTTTTTTAAAAAAACAGAATGAATTGATGTCTTATTTT
ATAAATGTTCTATATTTATTAGGAGAAAACTTTATATTGCCTTTTTTATCAATCATGTAACAGGCTTATAGCTTTCCAACAGAGCTGCTT
GCCAAACAATTTTTTTTGTTTATTAAACAGTGCTGAAACAAACAGGATCAGCATTTACTTAAGATGTTAAGAATGAGGACTTTTAATCAG
CCGAACCAAGATATTGTTACCTGTATGCATTCCCAAAGTCTAGATGCTCAGTATGTTCAGTCATATCTTTCAGAATCAGTGAACCGATTA
CCCTTTTTTTGGTATTCACTCTACATCTGCCAACCTAGTTCACCTTGGTTTTGTGTCTGCTGTAGAAGGGAACCATAACTTGGTTAAACC
GTAGGGATTATCATTGTATACATGCTGTGAACATGTATATGTGCAAGTTTTAATGTATTCTATGTTGTAGGCTTATTATTTAATTTTACC
ACTTCATCACTTTTGTACAGTGGCCAAGCAGACACCTCAAACTCCAGCATTTACATTAAGTGCATTTGTACATTTTAGGCCACTGGATCC
AGATTTTATATTGGCAGTTATTGAGGGCAAAAGCAATATATTGTAACAGAATGTATAAATATTTTTGATAAAACAGTCTATATTTTATTA
AAAAATGAATTATAACACTAAAGCTGTACCTCAAAAGTCTCAAAAATAATTTGATGAAATATTTTATACAACTCTTCAAAGGATCCGTCT
GTGGCTTTTTATACTCTTTTAGGGTTGTCTTTTTACAAACCATGACTTTCCACTTGCCTGTAGTTTTTTGTTTGTTTTGGTTTGGTTTGA
TTTTATATTTTTTTCTCCTAATCTATGACTTTATTGTTTTTTCTTAGTTTAGTAATAGCATCTTTGATCCTGTGCTTAGCATGTTAGGGT
CATTATACCTCAGGAATAGCAAGCTGTTAAGTAACCATACTGAATTAACTATTTAATTACAGTGAGCTCATCTCTTAAAAATTGTTCAGG
TGTAAATCTTATGAGAAACATGAAAAAGCACACTGATTTATGGAGAGTTGAGCTAAAAACATTTATAAATATTTGCTGGGATGTTTTAGC
ATCTTTTCATTGTACTCTGAGAACAATTAAAATTGTCCAGAGATCATTTATATTACCTTCCAAATTGTTTATTACCCAAGATCCTTTGGG
AGAAAATCTTATAGAATGGGGGAACAATATGTGGTTTAAAGTTATTTTAAAATGCCAGTTAATTTCCTCGGCAAAGGACAATAGAGGAAC
TTAGCTTAATTGTCTGGCTTTAATTTAAACTGTGTTAATACAACATTAAAATAAAACACTAAATACTTTTGAGGTACAGTCTGCTCACTT
TTTTGGTTCTCAAATAGCAAAGAAAGTAATGTCTAAAATAGGCTCTTAGCATTAAAAACTGACAGCATTTCGTAACTACACAGTGTACAG
AATTTTTTTTTAATTGAAGTCAATCACTAAAAAAATTAGAAGGCAGGGTCTATTTACACAATTAAGCTGAAGAAAGCACTAATTTTTTGT
AGTTTAAAATATATATATATTTTAGTCAGATTTAAAATTTTAAGCTTTATAGAGTGTAAATATATTTTGCTATTACTGTATGTGTATGTG
ACTGCTCAAGCACTTTGTAAAGAAATTAGGATATTTTAGAATGGTACACTATGCATTCAAATGAAATGTGCCTTTCACTATGTCATTCTA
AGAAAACAAGTGTTTTTTGCAGTCATAAATTATCACAAATGCACAAATTAAAGTCTATATAGATTGAAATTTGTAACTTTGGTTTTAAGT
ATTCTTTCCTTTTAGAAACTTCCTAATGATTAAAATATACTTTAACTTTTCTGTGTTCAAAATCTCAAAGACTAATTAACTTTAATAAAC
ATTCTTGCAAGTACTTTTTGTCCTAGTGAAGGCTTAAAACCATGAACATTCAGAGCAAACTGTCCACTTCATTGGGAATAATGGGAAAAG
TTTGTATTCTGCTCCTGTAAGGTCAGTAGCATCTTTTATTTGAAGCATATTTATGGACTGCTTACTGTGTATAGATACTGAGAATAGGAA
GTTTTTTTTTTTAAAGCAACAAAATGTTGATGAATGAAGAACAGCCTGTTTTAATTAAGATGCAAGCACCAGTATTGTATGTACTTTTCT

>95436_95436_8_TUFT1-PKN2_TUFT1_chr1_151512902_ENST00000392712_PKN2_chr1_89206671_ENST00000370521_length(amino acids)=994AA_BP=26
MRPRGKMNGTRNWCTLVDVHPEDQAAGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKELKIKEGAENLRKVTTDKKSLA
YVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPRTPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDR
KLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQAR
FNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVAASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSK
ATSVALPGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRDW
RSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNH
SGTFSPQAPVPTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPGQDSETVFDIQNDRNSILPKS
QSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFE
TVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIAD
FGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR
LLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYI

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Fusion Gene PPI Analysis for TUFT1-PKN2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TUFT1-PKN2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TUFT1-PKN2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource