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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:TXNL4B-SMG1 (FusionGDB2 ID:95597) |
Fusion Gene Summary for TXNL4B-SMG1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TXNL4B-SMG1 | Fusion gene ID: 95597 | Hgene | Tgene | Gene symbol | TXNL4B | SMG1 | Gene ID | 54957 | 23049 |
| Gene name | thioredoxin like 4B | SMG1 nonsense mediated mRNA decay associated PI3K related kinase | |
| Synonyms | DLP|Dim2 | 61E3.4|ATX|LIP | |
| Cytomap | 16q22.2 | 16p12.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | thioredoxin-like protein 4BDim1-like protein | serine/threonine-protein kinase SMG1PI-3-kinase-related kinase SMG-1SMG1 phosphatidylinositol 3-kinase-related kinaselambda-interacting proteinlambda/iota protein kinase C-interacting proteinsmg-1 homolog, phosphatidylinositol 3-kinase-related kinase | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000268483, ENST00000423037, ENST00000426362, | ENST00000567737, ENST00000389467, ENST00000446231, ENST00000565224, | |
| Fusion gene scores | * DoF score | 6 X 5 X 3=90 | 17 X 19 X 7=2261 |
| # samples | 6 | 18 | |
| ** MAII score | log2(6/90*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(18/2261*10)=-3.65089218042185 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: TXNL4B [Title/Abstract] AND SMG1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | TXNL4B(72122885)-SMG1(18891041), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | TXNL4B-SMG1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. TXNL4B-SMG1 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF. TXNL4B-SMG1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. TXNL4B-SMG1 seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | SMG1 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 11544179 |
| Tgene | SMG1 | GO:0018105 | peptidyl-serine phosphorylation | 11544179|15175154 |
| Tgene | SMG1 | GO:0046777 | protein autophosphorylation | 11331269|11544179 |
| Tgene | SMG1 | GO:0046854 | phosphatidylinositol phosphorylation | 11331269 |
| Tgene | SMG1 | GO:2001020 | regulation of response to DNA damage stimulus | 15175154 |
| Fusion gene breakpoints across TXNL4B (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across SMG1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | ESCA | TCGA-Q9-A6FU | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - |
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Fusion Gene ORF analysis for TXNL4B-SMG1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000268483 | ENST00000567737 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - |
| 5CDS-intron | ENST00000423037 | ENST00000567737 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - |
| 5CDS-intron | ENST00000426362 | ENST00000567737 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - |
| Frame-shift | ENST00000268483 | ENST00000389467 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - |
| Frame-shift | ENST00000268483 | ENST00000446231 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - |
| Frame-shift | ENST00000268483 | ENST00000565224 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - |
| In-frame | ENST00000423037 | ENST00000389467 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - |
| In-frame | ENST00000423037 | ENST00000446231 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - |
| In-frame | ENST00000423037 | ENST00000565224 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - |
| In-frame | ENST00000426362 | ENST00000389467 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - |
| In-frame | ENST00000426362 | ENST00000446231 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - |
| In-frame | ENST00000426362 | ENST00000565224 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000423037 | TXNL4B | chr16 | 72122885 | - | ENST00000389467 | SMG1 | chr16 | 18891041 | - | 14958 | 546 | 549 | 10241 | 3230 |
| ENST00000423037 | TXNL4B | chr16 | 72122885 | - | ENST00000446231 | SMG1 | chr16 | 18891041 | - | 14955 | 546 | 549 | 10238 | 3229 |
| ENST00000423037 | TXNL4B | chr16 | 72122885 | - | ENST00000565224 | SMG1 | chr16 | 18891041 | - | 1659 | 546 | 549 | 1154 | 201 |
| ENST00000426362 | TXNL4B | chr16 | 72122885 | - | ENST00000389467 | SMG1 | chr16 | 18891041 | - | 14971 | 559 | 562 | 10254 | 3230 |
| ENST00000426362 | TXNL4B | chr16 | 72122885 | - | ENST00000446231 | SMG1 | chr16 | 18891041 | - | 14968 | 559 | 562 | 10251 | 3229 |
| ENST00000426362 | TXNL4B | chr16 | 72122885 | - | ENST00000565224 | SMG1 | chr16 | 18891041 | - | 1672 | 559 | 562 | 1167 | 201 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000423037 | ENST00000389467 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - | 0.000482853 | 0.9995172 |
| ENST00000423037 | ENST00000446231 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - | 0.000780448 | 0.99921954 |
| ENST00000423037 | ENST00000565224 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - | 0.000592499 | 0.99940753 |
| ENST00000426362 | ENST00000389467 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - | 0.000529163 | 0.9994709 |
| ENST00000426362 | ENST00000446231 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - | 0.000853367 | 0.9991466 |
| ENST00000426362 | ENST00000565224 | TXNL4B | chr16 | 72122885 | - | SMG1 | chr16 | 18891041 | - | 0.000922177 | 0.9990778 |
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Fusion Genomic Features for TXNL4B-SMG1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for TXNL4B-SMG1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:72122885/chr16:18891041) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | SMG1 | chr16:72122885 | chr16:18891041 | ENST00000446231 | 9 | 63 | 1283_1866 | 431 | 3662.0 | Domain | FAT | |
| Tgene | SMG1 | chr16:72122885 | chr16:18891041 | ENST00000446231 | 9 | 63 | 2150_2478 | 431 | 3662.0 | Domain | PI3K/PI4K | |
| Tgene | SMG1 | chr16:72122885 | chr16:18891041 | ENST00000446231 | 9 | 63 | 3629_3661 | 431 | 3662.0 | Domain | FATC | |
| Tgene | SMG1 | chr16:72122885 | chr16:18891041 | ENST00000446231 | 9 | 63 | 1817_1852 | 431 | 3662.0 | Repeat | Note=HEAT |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for TXNL4B-SMG1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >95597_95597_1_TXNL4B-SMG1_TXNL4B_chr16_72122885_ENST00000423037_SMG1_chr16_18891041_ENST00000389467_length(transcript)=14958nt_BP=546nt ACGCCCGATTCCTGGATCCAAGTGTGGAACGGTACGCCAACAGGCTCTCAAGGCCTCCTCTGGGGCTCTGATCAGACACTTCCGAGTCTC CTTGTGACCAATCACTCTTAGCCTAAGAGACTACATCCCGCCTCTAGTCTGGGGGCAGGAAAAGGAGGGGAAAAAGGTCGACCATCTTTA ATACGGGCGGAGGTGACGCCTAGCTTCCGGTCAGAGCCGAGCAAGGAGTGACAGTGAGGATTCACATTTGGGTTATTTCAAGATGAGCTT CCTACTGCCCAAGCTGACTAGCAAAAAGGAAGTAGACCAGGCGATAAAAAGTACTGCTGAGAAGGTGTTGGTTCTCAGGTTTGGGAGAGA TGAAGATCCTGTCTGTCTGCAGCTAGATGATATTCTTTCTAAGACCTCTTCTGACTTAAGTAAAATGGCTGCTATATACCTGGTAGATGT GGACCAAACTGCAGTTTATACACAGTATTTTGACATCAGTTATATTCCATCTACTGTCTTTTTCTTCAATGGGCAGCATATGAAAGTGGA TTATGGGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAGGCTGTGTTGACAGCTGCTAATGAGTGT GTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACATATGGATTAGACCAACTGGAGAATTGC CAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAGATAAATACGAAACTGCCATCATCATTT GTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAGGTTGTTGCTGTAGCCCATGCTGTTTAT CAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGAGAAATGACTTGTGCCCTAAACAACCTC CTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCATGTGTTCAATGTAGACAATGCAAAATTT GTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGGATGTGGGCGCTATCTCCAACTGTCTTT GCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCTCTACACATTGTAT TCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGTGATTAGCACTGTA ACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCAGGACACGAGGAAA CTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCCGTCTTTCCATAAA TTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGCTCTGTCCTCTTCC TTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACAAGCATTTGGAAAA CTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATTAAGAAGTCACATG AGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCATAGAACAGGGAAG GACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCTCCTGAAGACAGAT GCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAGAGCTCAAGACACC TTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGACAACTGCAGACAAT GATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTATAATGCATACGAG GGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGACTGGCTAACGCGG ATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCTTACAGAGATGAAA ACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTGTCCTGAAGCTATA CAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGAAGGGAGGTTTGAA AAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATCGGTGCTCACCTTA GCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACCGACTGACTCTTCC CCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGAATGGCAGAACGCT ATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAGCAGCTTTGAGTCT GGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAAAGAAAAAATAGAC ATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAGAAGTTCTGTTTGT TTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAAGCAAACATCCCGC ATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTATTGCTCATCTGCT TTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATGTAAACAGCATGAC GTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGAACAAACAGTCCCAATTAGAAGC CATCTCATGGAATTAGGTCTAACAGCAGCAAAATTTGCTAGAAAACGAGGGAATGTGTCCCTTGCAACAAGACTGCTGGCACAGTGCAGT GAAGTTCAGCTGGGAAAGACCACCACTGCACAGGATTTAGTCCAACATTTTAAAAAACTATCAACCCAAGGTCAAGTGGATGAAAAATGG GGGCCCGAACTTGATATTGAAAAAACCAAATTGCTTTATACAGCAGGCCAGTCAACACATGCAATGGAAATGTTGAGTTCTTGTGCCATA TCTTTCTGCAAGTCTGTGAAAGCTGAATATGCAGTTGCTAAATCAATTCTGACACTGGCTAAATGGATCCAGGCAGAATGGAAAGAGATT TCAGGACAGCTGAAACAGGTTTACAGAGCTCAGCACCAACAGAACTTCACAGGTCTTTCTACTTTGTCTAAAAACATACTCACTCTAATA GAACTGCCATCTGTTAATACGATGGAAGAAGAGTATCCTCGGATCGAGAGTGAATCTACAGTGCATATTGGAGTTGGAGAACCTGACTTC ATTTTGGGACAGTTGTATCACCTGTCTTCAGTACAGGCACCTGAAGTAGCCAAATCTTGGGCAGCGTTGGCCAGCTGGGCTTATAGGTGG GGCAGAAAGGTGGTTGACAATGCCAGTCAGGGAGAAGGTGTTCGTCTGCTGCCTAGAGAAAAATCTGAAGTTCAGAATCTACTTCCAGAC ACTATAACTGAGGAAGAGAAAGAGAGAATATATGGTATTCTTGGACAGGCTGTGTGTCGGCCGGCGGGGATTCAGGATGAAGATATAACA CTTCAGATAACTGAGAGTGAAGACAACGAAGAAGATGACATGGTTGATGTTATCTGGCGTCAGTTGATATCAAGCTGCCCATGGCTTTCA GAACTTGATGAAAGTGCAACTGAAGGAGTTATTAAAGTGTGGAGGAAAGTTGTAGATAGAATATTCAGCCTGTACAAACTCTCTTGCAGT GCATACTTTACTTTCCTTAAACTCAACGCTGGTCAAATTCCTTTAGATGAGGATGACCCTAGGCTGCATTTAAGTCACAGAGTGGAACAG AGCACTGATGACATGATTGTGATGGCCACATTGCGCCTGCTGCGGTTGCTCGTGAAGCATGCTGGTGAGCTTCGGCAGTATCTGGAGCAC GGCTTGGAGACAACACCCACTGCACCATGGAGAGGAATTATTCCGCAACTTTTCTCACGCTTAAACCACCCTGAAGTGTATGTGCGCCAA AGTATTTGTAACCTTCTCTGCCGTGTGGCTCAAGATTCCCCACATCTCATATTGTATCCTGCAATAGTGGGTACCATATCGCTTAGTAGT GAATCCCAGGCTTCAGGAAATAAATTTTCCACTGCAATTCCAACTTTACTTGGCAATATTCAAGGAGAAGAATTGCTGGTTTCTGAATGT GAGGGAGGAAGTCCTCCTGCATCTCAGGATAGCAATAAGGATGAACCTAAAAGTGGATTAAATGAAGACCAAGCCATGATGCAGGATTGT TACAGCAAAATTGTAGATAAGCTGTCCTCTGCAAACCCCACCATGGTATTACAGGTTCAGATGCTCGTGGCTGAACTGCGCAGGGTCACT GTGCTCTGGGATGAGCTCTGGCTGGGAGTTTTGCTGCAACAACACATGTATGTCCTGAGACGAATTCAGCAGCTTGAAGATGAGGTGAAG AGAGTCCAGAACAACAACACCTTACGCAAAGAAGAGAAAATTGCAATCATGAGGGAGAAGCACACAGCTTTGATGAAGCCCATCGTATTT GCTTTGGAGCATGTGAGGAGTATCACAGCGGCTCCTGCAGAAACACCTCATGAAAAATGGTTTCAGGATAACTATGGTGATGCCATTGAA AATGCCCTAGAAAAACTGAAGACTCCATTGAACCCTGCAAAGCCTGGGAGCAGCTGGATTCCATTTAAAGAGATAATGCTAAGTTTGCAA CAGAGAGCACAGAAACGTGCAAGTTACATCTTGCGTCTTGAAGAAATCAGTCCATGGTTGGCTGCCATGACTAACACTGAAATTGCTCTT CCTGGGGAAGTCTCAGCCAGAGACACTGTCACAATCCATAGTGTGGGCGGAACCATCACAATCTTACCGACTAAAACCAAGCCAAAGAAA CTTCTCTTTCTTGGATCAGATGGGAAGAGCTATCCTTATCTTTTCAAAGGACTGGAGGATTTACATCTGGATGAGAGAATAATGCAGTTC CTATCTATTGTGAATACCATGTTTGCTACAATTAATCGCCAAGAAACACCCCGGTTCCATGCTCGACACTATTCTGTAACACCACTAGGA ACAAGATCAGGACTAATCCAGTGGGTAGATGGAGCCACACCCTTATTTGGTCTTTACAAACGATGGCAACAACGGGAAGCTGCCTTACAA GCACAAAAGGCCCAAGATTCCTACCAAACTCCTCAGAATCCTGGAATTGTACCCCGTCCTAGTGAACTTTATTACAGTAAAATTGGCCCT GCTTTGAAAACAGTTGGGCTTAGCCTGGATGTGTCCCGTCGGGATTGGCCTCTTCATGTAATGAAGGCAGTATTGGAAGAGTTAATGGAG GCCACACCCCCGAATCTCCTTGCCAAAGAGCTCTGGTCATCTTGCACAACACCTGATGAATGGTGGAGAGTTACGCAGTCTTATGCAAGA TCTACTGCAGTCATGTCTATGGTTGGATACATAATTGGCCTTGGAGACAGACATCTGGATAATGTTCTTATAGATATGACGACTGGAGAA GTTGTTCACATAGATTACAATGTTTGCTTTGAAAAAGGTAAAAGCCTTAGAGTTCCTGAGAAAGTACCTTTTCGAATGACACAAAACATT GAAACAGCACTGGGTGTAACTGGAGTAGAAGGTGTATTTAGGCTTTCATGTGAGCAGGTTTTACACATTATGCGGCGTGGCAGAGAGACC CTGCTGACGCTGCTGGAGGCCTTTGTGTACGACCCTCTGGTGGACTGGACAGCAGGAGGCGAGGCTGGGTTTGCTGGTGCTGTCTATGGT GGAGGTGGCCAGCAGGCCGAGAGCAAGCAGAGCAAGAGAGAGATGGAGCGAGAGATCACCCGCAGCCTGTTTTCTTCTAGAGTAGCTGAG ATTAAGGTGAACTGGTTTAAGAATAGAGATGAGATGCTGGTTGTGCTTCCCAAGTTGGACGGTAGCTTAGATGAATACCTAAGCTTGCAA GAGCAACTGACAGATGTGGAAAAACTGCAGGGCAAACTACTGGAGGAAATAGAGTTTCTAGAAGGAGCTGAAGGGGTGGATCATCCTTCT CATACTCTGCAACACAGGTATTCTGAGCACACCCAACTACAGACTCAGCAAAGAGCTGTTCAGGAAGCAATCCAGGTGAAGCTGAATGAA TTTGAACAATGGATAACACATTATCAGGCTGCATTCAATAATTTAGAAGCAACACAGCTTGCAAGCTTGCTTCAAGAGATAAGCACACAA ATGGACCTTGGTCCTCCAAGTTACGTGCCAGCAACAGCCTTTCTGCAGAATGCTGGTCAGGCCCACTTGATTAGCCAGTGCGAGCAGCTG GAGGGGGAGGTTGGTGCTCTCCTGCAGCAGAGGCGCTCCGTGCTCCGTGGCTGTCTGGAGCAACTGCATCACTATGCAACCGTGGCCCTG CAGTATCCGAAGGCCATATTTCAGAAACATCGAATTGAACAGTGGAAGACCTGGATGGAAGAGCTCATCTGTAACACCACAGTAGAGCGT TGTCAAGAGCTCTATAGGAAATATGAAATGCAATATGCTCCCCAGCCACCCCCAACAGTGTGTCAGTTCATCACTGCCACTGAAATGACC CTGCAGCGATACGCAGCAGACATCAACAGCAGACTTATTAGACAAGTGGAACGCTTGAAACAGGAAGCTGTCACTGTGCCAGTTTGTGAA GATCAGTTGAAAGAAATTGAACGTTGCATTAAAGTTTTCCTTCATGAGAATGGAGAAGAAGGATCTTTGAGTCTAGCAAGTGTTATTATT TCTGCCCTTTGTACCCTTACAAGGCGTAACCTGATGATGGAAGGTGCAGCGTCAAGTGCTGGAGAACAGCTGGTTGATCTGACTTCTCGG GATGGAGCCTGGTTCTTGGAGGAACTCTGCAGTATGAGCGGAAACGTCACCTGCTTGGTTCAGTTACTGAAGCAGTGCCACCTGGTGCCA CAGGACTTAGATATCCCGAACCCCATGGAAGCGTCTGAGACAGTTCACTTAGCCAATGGAGTGTATACCTCACTTCAGGAATTGAATTCG AATTTCCGGCAAATCATATTTCCAGAAGCACTTCGATGTTTAATGAAAGGGGAATACACGTTAGAAAGTATGCTGCATGAACTGGACGGT CTTATTGAGCAGACCACCGATGGCGTTCCCCTGCAGACTCTAGTGGAATCTCTTCAGGCCTACTTAAGAAACGCAGCTATGGGACTGGAA GAAGAAACACATGCTCATTACATCGATGTTGCCAGACTACTACATGCTCAGTACGGTGAATTAATCCAACCGAGAAATGGTTCAGTTGAT GAAACACCCAAAATGTCAGCTGGCCAGATGCTTTTGGTAGCATTCGATGGCATGTTTGCTCAAGTTGAAACTGCTTTCAGCTTATTAGTT GAAAAGTTGAACAAGATGGAAATTCCCATAGCTTGGCGAAAGATTGACATCATAAGGGAAGCCAGGAGTACTCAAGTTAATTTTTTTGAT GATGATAATCACCGGCAGGTGCTAGAAGAGATTTTCTTTCTAAAAAGACTACAGACTATTAAGGAGTTCTTCAGGCTCTGTGGTACCTTT TCTAAAACATTGTCAGGATCAAGTTCACTTGAAGATCAGAATACTGTGAATGGGCCTGTACAGATTGTCAATGTGAAAACCCTTTTTAGA AACTCTTGTTTCAGTGAAGACCAAATGGCCAAACCTATCAAGGCATTCACAGCTGACTTTGTGAGGCAGCTCTTGATAGGGCTACCCAAC CAAGCCCTCGGACTCACACTGTGCAGTTTTATCAGTGCTCTGGGTGTAGACATCATTGCTCAAGTAGAGGCAAAGGACTTTGGTGCCGAA AGCAAAGTTTCTGTTGATGATCTCTGTAAGAAAGCGGTGGAACATAACATCCAGATAGGGAAGTTCTCTCAGCTGGTTATGAACAGGGCA ACTGTGTTAGCAAGTTCTTACGACACTGCCTGGAAGAAGCATGACTTGGTGCGAAGGCTAGAAACCAGTATTTCTTCTTGTAAGACAAGC CTGCAGCGGGTTCAGCTGCATATTGCCATGTTTCAGCAGTGGCAACATGAAGATCTACTTATCAATAGACCACAAGCCATGTCAGTCACA CCTCCCCCACGGTCTGCTATCCTAACCAGCATGAAAAAGAAGCTGCATACCCTGAGCCAGATTGAAACTTCTATTGCAACAGTTCAGGAG AAGCTAGCTGCACTTGAATCAAGTATTGAACAGCGACTCAAGTGGGCAGGTGGTGCCAACCCTGCATTGGCCCCTGTACTACAAGATTTT GAAGCAACGATAGCTGAAAGAAGAAATCTTGTCCTTAAAGAGAGCCAAAGAGCAAGTCAGGTCACATTTCTCTGCAGCAATATCATTCAT TTTGAAAGTTTACGAACAAGAACTGCAGAAGCCTTAAACCTGGATGCGGCGTTATTTGAACTAATCAAGCGATGTCAGCAGATGTGTTCG TTTGCATCACAGTTTAACAGTTCAGTGTCTGAGTTAGAGCTTCGTTTATTACAGAGAGTGGACACTGGTCTTGAACATCCTATTGGCAGC TCTGAATGGCTTTTGTCAGCACACAAACAGTTGACCCAGGATATGTCTACTCAGAGGGCAATTCAGACAGAGAAAGAGCAGCAGATAGAA ACGGTCTGTGAAACAATTCAGAATCTGGTTGATAATATAAAGACTGTGCTCACTGGTCATAACCGACAGCTTGGAGATGTCAAACATCTC TTGAAAGCTATGGCTAAGGATGAAGAAGCTGCTCTGGCAGATGGTGAAGATGTTCCCTATGAGAACAGTGTTAGGCAGTTTTTGGGTGAA TATAAATCATGGCAAGACAACATTCAAACAGTTCTATTTACATTAGTCCAGGCTATGGGTCAGGTTCGAAGTCAAGAACACGTTGAAATG CTCCAGGAAATCACTCCCACCTTGAAAGAACTGAAAACACAAAGTCAGAGTATCTATAATAATTTAGTGAGTTTTGCATCACCCTTAGTC ACCGATGCAACAAATGAATGTTCGAGTCCAACGTCATCTGCTACTTATCAGCCATCCTTCGCTGCAGCAGTCCGGAGTAACACTGGCCAG AAGACTCAGCCTGATGTCATGTCACAGAATGCTAGAAAGCTGATCCAAAAAAATCTTGCTACATCAGCTGATACTCCACCAAGCACCGTT CCAGGAACTGGCAAGAGTGTTGCTTGTAGTCCTAAAAAGGCAGTCAGAGACCCTAAAACTGGGAAAGCGGTGCAAGAGAGAAACTCCTAT GCAGTGAGTGTGTGGAAGAGAGTGAAAGCCAAGTTAGAGGGCCGAGATGTTGATCCGAATAGGAGGATGTCAGTTGCTGAACAGGTTGAC TATGTCATTAAGGAAGCAACTAATCTAGATAACTTGGCTCAGCTGTATGAAGGTTGGACAGCCTGGGTGTGAATGGCAAGACAGTAGATG AGTCTGGTTAAGCGAGGTCAGACATCCACCAGAATCAACTCAGCCTCAGGCATCCAAAGCCACACCACAGTCGGTGGTGATGCAACTGGG GGCTTACTCTGAGGAAACCTAGGAAATCTCGGTGCACTAGGAAGTGAATCCCGCAGGACAGCTGCACTCAGGGATACGCCCAACACCATG GCCTGCAACCCCAGGGTCAAGGGTGAAGGAAAGCAAGCTCACCGCCTGAACACGGAGATTGTCTTTCTGCCACAGAACAGCAGCAGACGT GTCGGGAGGTTAGCTGCGGAAAGAAATCGGGATGCCGCGGAGCACAGAGTGATTTGGAACTCCATTCCACCTGACCCTGTGTGTACAATC CAGGAAAAAAACAAACCCCACTCAGAAACAGAGAAAACTGGGGTCGCGAAGAAATCACAGCCAAGGAAGATTTGATGCATTCAGATTCTC GTGTAACACTTGTTGCTTGGCAACAGTACTGGTTGGGTTGACCAGTAAGTAGAAAAAGGCTAAAGGCTATGCGATATGAATTTCAGAAAT GGACTGAAAATGGAGAGCTATGTAACAGATACACTACAGTAGAAGAACTTACTTCTGAAATGAAGGGAAAAAAACCACCCCATCGTTCCC TACTCCTCCCCACCACTTACCCGTTCCCCCTTTACCTAATCTAGTAGATTAGCCATCTTTCAAATTCACTTTTATTTCAGTCCTTATATT TCATATACTTCCGTCTCGATGCTGTTAACAACTTCTGATAACATGGAAAATTCAAGGATTGTTTAAAGGTCTGATGATCACACACAAAAT GTAATTCCGGTTATTTAAGTCATTTCTGTGATTCTATCATGTACAGTTTCCAGAATTGTCACTGTGCATTCAAAAGTAATGAATCTAACA GACATTTGATTTAATGTACACTCCCTTTTGCTTATAGTGTGCATTTTTTTTGGAGGTCATTCAAATTTTCCCTCTTCTGTGATAGCTGTA GTTTCTTTCATAGAAAGTAGCTAATCCAGTGTAATCTTTTACCTTTTTAAAAACCAAGATAGAGTATCTATTAGAGTTTTACATTGTTGA TGATAGATTAACAATAAAGTGATGTTCTGGTGGAGGTAGACTGAAATTTTTTTAATTCATGTTTTTCATTTGATACTTTTAATTTACACT TAGTAAATTAAAAGTTGTTTAATTTACTTGGCATTTTAGGACATGTACATGAAACAGTGAAAATGAGATCCACCAACATCTTTTATTAAG TTCAGTTATTAGTCTGTGAAGTGCTTTACTTTTTGCACAATTTTAATAGCTTGCTATTCAGTAATACATTATAGTGAATTCATGATCAAG GTTTCCTTAAATTTAGCATTGCATTTCAGTACTGACTGTGTAAGCTAAATTGCTGATCCAAAATAAAAACCCAGACTAGAATAGGGTTCT TAAAATCAAGTATCAATACAAAATAGAACACAATTAAAATCTTAATTGTTGGCTGGGCACAGTGGCTCACGCCTGTAATCCCAGCACTTT GGGAGGCCGAGGCGGGCGGATCATGAGGTTAGGAGAGCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTTTACTAAAAATACAAAA AAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGGAGGCGGAGC TTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAGAGCTAGACTCTGTGTCAAAAATAAATGACTAGATAAAAAAAAA AATTGTTTGAGTACATTTTCCCTGCATTTTAGAGATTAGGACAGTGGTCACTTTCTAGTTGCCGTCTTCACAGACAAACTTGAAAGGTAT TAAGGAAAAAATTCCACATAGCTCTGGGCCTTTTTTGTATTCTGATTGCCACGTTAATCTGTAATCGTTAAGTACCCATGAAAGAATGTG TTTCAGTATCAGTGCTTTTTTGGTACTTTAACAAGTATTGTAGGCACGGTGGATTTTTTTGAAATACCCATGTGTCCAATAGCAAGTTAA GGAACCTAGCGCATCAAATTTTGTTTTCTTCATTCATTTGGAACCTTATTTTCGCAAAAAACCTAGCTGGAATAATAATGCCATATTGTA TTTTGCACACTGCTTTATTTTCTAGAGGCTCTGGGAGCAAATTACATTCATCACATTACCTCTGCTCTCTCAAGATTAAAGTCTTTCAGC AACATTCTTTATTGTCATCATAAGGAAAAACTTTTATCGCAATGATAGTCAGTTCACATTAGTTTAGCACTATAGATAGTATTCAGAAAT TGCTTTCTCTTTGGTAAAGAAGATAAATAGGTGAATTTTATTGCCTGTGTTTTCAGGCTTCAGAGGTACCTGGCACCTTACTCAAGCAAA AACAAAAAACAGCTTTACTTCAAAAGCATGTGCCTCTGGTAAATTATCCATCACTTTTGTTTTAAAGTGGTCCCTCCAAGAATAATGTGG CATACACAGTGGGTTTGGTTGTAAGGCAGATGTAATAGATGACTTCAAAAGCCTGCTCCTTACTGCACTCTGGACAAGGCCCTGGTCTGT ATAGTTTGGCTTCCTCTGTTAAGTCATTCTACAAGGTGACTTGCCATTTGAACTTTCGTAAGAGACCTCAGCAGTTAGACTGAGAAAAGT TAGAGTGCTGTAGTTATGAAGTCATACATTTTTGATAAAATACCTGTGGAAAACCAGGGATCCTCTCCTGTTTCTCTCTCTTGCCTCCCC CTTTCCCTCCATTCCTCTGTCGCCTCCCCCTCTCCTCCACTTTCTTTAAGAATCAGGGGGTACAGAATAACCTACAAACAACCTCTTCAA AGTACCCTTGGAAATTGAAGTTCAATCTTAAGTTTTTTGCTGTCTTTAATTTACTAGAATTGCCTAATTTTTAGTTGATTTCTCTACAGA GCTTAGCTTGTGTAGTTATTTCTCTTTTACTGTTGCTTTGGTGTGTCTTGAAGTTTGATTGATTATTTTTGGTCATTGAGTTCTTAGTGT AGTTTGCTAGATGATTATTAAGATTCTTTTGTGTCTGACACTTGTGGTGAGTTGCTTTTGAAATCTGTTGAGATTTCCATGTGAGAACTG ATAATCAGGCTCTTGATCTGCTTCCCTAAATTACTTTTTTAGAGCCCAAACCCCAGGTTTAGGGTGAGGGTTTGTAATACAAAGAAACAC TTCCATCACTTCTGCCCTTAACCCTTGCCTCTATTACCTAAGCTTAGTAAGTAGTTTTCTTAATATTGTCCAATGTTTGGTGTTATCTGC ATTGTTTTTTGTTTTTTTAATTGTGGTTGTTCTGACGTGTGAAATTTAAGGAAAGAGCCATTTTTTAAAAATGCCGAGCAGGGCAATGCA AGTACAGCCAAATATTAGACTTGATGTGCAATCTTCGGTCCTTTTTAATCTGGGGTATTATAGGCAGTACTTTAAATTGCAAAGTCTTCC GGGCCTATTTTCCTCTACATTTTTGTAATTAACTCTGGGGGCTTACTTGTTTTGGCAGTACTGAAATCAAAGGAGCTGGTTCTTCTTTTC TCCCAATTATTTTCATATGAAAGCACCTACAATTAGCCTGTTAGTCCTATTCAGATACATCAAATATCAGTGAATGCTTTACTATTCGCA CATTTAAGCATCTTTGTTTTACATAAAATTAGAGTATGAAAACCAGTGTTCAATTTTTTATCTTGTTGAGCTTGTAAAATGCCAGCAATT TAAAACTAGGACTTTTCCCCCCATAAGCCAAGGAGGTAGAATTACTAATACAAGGGTTAAAGAAGGTAGATTTTGTTTTCAATATTTGGG TAATATTAGAAAGATTCTTCCCACAGGGAAGAACTAGCAAGTGTCCCAATTTTTTCCAAACGTTGGGGAGGGGAAAATTCACTGTATCAT GAAACCCTAAGGGTTTGTTGCACTTCCTGCTTTTTAGGCCTGGATAACAGTATCACCATCCTTATTTACAGAAGGGTAAAACTGACTCTT AATGAGAAAAGCTTTATAAGTTCAAGGGCTGTAAAATATGAACTACTTAGGGTCGTTTGCCTTCCATGGGAACTTGGCTAGACTTAGAAA AAGCTGTTTGTTGTGCTAATGTAAAAGTGTCATACAATTTAGAAGATTTTTGAAGATGGTAAACTTAGAAGAATTCTATGTTCTGAAATG CACACTTTTAGAATGTTTTTCTTTGAAAACAGGCTAATAGTTTTTTCTTTTTTTGACAAAGTTTCAGCTCCTCTTTAAAGTTATTGTGTC ATTTTTCTGGTTTAAATTTCCCTTATATTTCCACCTGTAATGTCAGTGGCAACAACATCATACTTCACTTACTTGTTAATTTACTTTTTA CCCTTATTCTAAGAGCAAGTTGAGTTGAACTGAATCTTCCTTGTCTTAGTAACAATGTATAAATAGTGGCTTTTCTGTACAAAAGGTTGT AATGCCTCCTGATGGATATAATTTTGTGATTGTATTTAAAAGTTGAATAAATCACACCAGCTTCCTGAAAATGTTCATAATGCATCTTTT GGAAAACAAATACATGCCTACTTTGTGCATATTTGCATTAACATGGCAAAGATTGTATGAAATACCTGTTTTTCAGAAAATAAAGGTTCA >95597_95597_1_TXNL4B-SMG1_TXNL4B_chr16_72122885_ENST00000423037_SMG1_chr16_18891041_ENST00000389467_length(amino acids)=3230AA_BP=1 MYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPSMTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEK LFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPVLETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVI FDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTA TKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPD DLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNW LERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEG HGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTS LSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANA GRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKF VECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAI GPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKEQTVPIRSHLM ELGLTAAKFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQSTHAMEMLSSCAISFC KSVKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLSTLSKNILTLIELPSVNTMEEEYPRIESESTVHIGVGEPDFILG QLYHLSSVQAPEVAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQAVCRPAGIQDEDITLQI TESEDNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQIPLDEDDPRLHLSHRVEQSTD DMIVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLILYPAIVGTISLSSESQ ASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLW DELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWFQDNYGDAIENAL EKLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKPKKLLF LGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQK AQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTA VMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLT LLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVLPKLDGSLDEYLSLQEQL TDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRYSEHTQLQTQQRAVQEAIQVKLNEFEQWITHYQAAFNNLEATQLASLLQEISTQMDL GPPSYVPATAFLQNAGQAHLISQCEQLEGEVGALLQQRRSVLRGCLEQLHHYATVALQYPKAIFQKHRIEQWKTWMEELICNTTVERCQE LYRKYEMQYAPQPPPTVCQFITATEMTLQRYAADINSRLIRQVERLKQEAVTVPVCEDQLKEIERCIKVFLHENGEEGSLSLASVIISAL CTLTRRNLMMEGAASSAGEQLVDLTSRDGAWFLEELCSMSGNVTCLVQLLKQCHLVPQDLDIPNPMEASETVHLANGVYTSLQELNSNFR QIIFPEALRCLMKGEYTLESMLHELDGLIEQTTDGVPLQTLVESLQAYLRNAAMGLEEETHAHYIDVARLLHAQYGELIQPRNGSVDETP KMSAGQMLLVAFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREARSTQVNFFDDDNHRQVLEEIFFLKRLQTIKEFFRLCGTFSKT LSGSSSLEDQNTVNGPVQIVNVKTLFRNSCFSEDQMAKPIKAFTADFVRQLLIGLPNQALGLTLCSFISALGVDIIAQVEAKDFGAESKV SVDDLCKKAVEHNIQIGKFSQLVMNRATVLASSYDTAWKKHDLVRRLETSISSCKTSLQRVQLHIAMFQQWQHEDLLINRPQAMSVTPPP RSAILTSMKKKLHTLSQIETSIATVQEKLAALESSIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQRASQVTFLCSNIIHFES LRTRTAEALNLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDTGLEHPIGSSEWLLSAHKQLTQDMSTQRAIQTEKEQQIETVC ETIQNLVDNIKTVLTGHNRQLGDVKHLLKAMAKDEEAALADGEDVPYENSVRQFLGEYKSWQDNIQTVLFTLVQAMGQVRSQEHVEMLQE ITPTLKELKTQSQSIYNNLVSFASPLVTDATNECSSPTSSATYQPSFAAAVRSNTGQKTQPDVMSQNARKLIQKNLATSADTPPSTVPGT -------------------------------------------------------------- >95597_95597_2_TXNL4B-SMG1_TXNL4B_chr16_72122885_ENST00000423037_SMG1_chr16_18891041_ENST00000446231_length(transcript)=14955nt_BP=546nt ACGCCCGATTCCTGGATCCAAGTGTGGAACGGTACGCCAACAGGCTCTCAAGGCCTCCTCTGGGGCTCTGATCAGACACTTCCGAGTCTC CTTGTGACCAATCACTCTTAGCCTAAGAGACTACATCCCGCCTCTAGTCTGGGGGCAGGAAAAGGAGGGGAAAAAGGTCGACCATCTTTA ATACGGGCGGAGGTGACGCCTAGCTTCCGGTCAGAGCCGAGCAAGGAGTGACAGTGAGGATTCACATTTGGGTTATTTCAAGATGAGCTT CCTACTGCCCAAGCTGACTAGCAAAAAGGAAGTAGACCAGGCGATAAAAAGTACTGCTGAGAAGGTGTTGGTTCTCAGGTTTGGGAGAGA TGAAGATCCTGTCTGTCTGCAGCTAGATGATATTCTTTCTAAGACCTCTTCTGACTTAAGTAAAATGGCTGCTATATACCTGGTAGATGT GGACCAAACTGCAGTTTATACACAGTATTTTGACATCAGTTATATTCCATCTACTGTCTTTTTCTTCAATGGGCAGCATATGAAAGTGGA TTATGGGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAGGCTGTGTTGACAGCTGCTAATGAGTGT GTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACATATGGATTAGACCAACTGGAGAATTGC CAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAGATAAATACGAAACTGCCATCATCATTT GTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAGGTTGTTGCTGTAGCCCATGCTGTTTAT CAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGAGAAATGACTTGTGCCCTAAACAACCTC CTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCATGTGTTCAATGTAGACAATGCAAAATTT GTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGGATGTGGGCGCTATCTCCAACTGTCTTT GCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCTCTACACATTGTAT TCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGTGATTAGCACTGTA ACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCAGGACACGAGGAAA CTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCCGTCTTTCCATAAA TTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGCTCTGTCCTCTTCC TTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACAAGCATTTGGAAAA CTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATTAAGAAGTCACATG AGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCATAGAACAGGGAAG GACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCTCCTGAAGACAGAT GCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAGAGCTCAAGACACC TTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGACAACTGCAGACAAT GATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTATAATGCATACGAG GGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGACTGGCTAACGCGG ATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCTTACAGAGATGAAA ACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTGTCCTGAAGCTATA CAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGAAGGGAGGTTTGAA AAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATCGGTGCTCACCTTA GCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACCGACTGACTCTTCC CCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGAATGGCAGAACGCT ATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAGCAGCTTTGAGTCT GGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAAAGAAAAAATAGAC ATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAGAAGTTCTGTTTGT TTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAAGCAAACATCCCGC ATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTATTGCTCATCTGCT TTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATGTAAACAGCATGAC GTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGAACAAACAGTCCCAATTAGAAGC CATCTCATGGAATTAGGTCTAACAGCAGCAAAATTTGCTAGAAAACGAGGGAATGTGTCCCTTGCAACAAGACTGCTGGCACAGTGCAGT GAAGTTCAGCTGGGAAAGACCACCACTGCACAGGATTTAGTCCAACATTTTAAAAAACTATCAACCCAAGGTCAAGTGGATGAAAAATGG GGGCCCGAACTTGATATTGAAAAAACCAAATTGCTTTATACAGCAGGCCAGTCAACACATGCAATGGAAATGTTGAGTTCTTGTGCCATA TCTTTCTGCAAGTCTGTGAAAGCTGAATATGCAGTTGCTAAATCAATTCTGACACTGGCTAAATGGATCCAGGCAGAATGGAAAGAGATT TCAGGACAGCTGAAACAGGTTTACAGAGCTCAGCACCAACAGAACTTCACAGGTCTTTCTACTTTGTCTAAAAACATACTCACTCTAATA GAACTGCCATCTGTTAATACGATGGAAGAAGAGTATCCTCGGATCGAGAGTGAATCTACAGTGCATATTGGAGTTGGAGAACCTGACTTC ATTTTGGGACAGTTGTATCACCTGTCTTCAGTACAGGCACCTGAAGTAGCCAAATCTTGGGCAGCGTTGGCCAGCTGGGCTTATAGGTGG GGCAGAAAGGTGGTTGACAATGCCAGTCAGGGAGAAGGTGTTCGTCTGCTGCCTAGAGAAAAATCTGAAGTTCAGAATCTACTTCCAGAC ACTATAACTGAGGAAGAGAAAGAGAGAATATATGGTATTCTTGGACAGGCTGTGTGTCGGCCGGCGGGGATTCAGGATGAAGATATAACA CTTCAGATAACTGAGAGTGAAGACAACGAAGAAGATGACATGGTTGATGTTATCTGGCGTCAGTTGATATCAAGCTGCCCATGGCTTTCA GAACTTGATGAAAGTGCAACTGAAGGAGTTATTAAAGTGTGGAGGAAAGTTGTAGATAGAATATTCAGCCTGTACAAACTCTCTTGCAGT GCATACTTTACTTTCCTTAAACTCAACGCTGGTCAAATTCCTTTAGATGAGGATGACCCTAGGCTGCATTTAAGTCACAGAGTGGAACAG AGCACTGATGACATGATTGTGATGGCCACATTGCGCCTGCTGCGGTTGCTCGTGAAGCATGCTGGTGAGCTTCGGCAGTATCTGGAGCAC GGCTTGGAGACAACACCCACTGCACCATGGAGAGGAATTATTCCGCAACTTTTCTCACGCTTAAACCACCCTGAAGTGTATGTGCGCCAA AGTATTTGTAACCTTCTCTGCCGTGTGGCTCAAGATTCCCCACATCTCATATTGTATCCTGCAATAGTGGGTACCATATCGCTTAGTAGT GAATCCCAGGCTTCAGGAAATAAATTTTCCACTGCAATTCCAACTTTACTTGGCAATATTCAAGGAGAAGAATTGCTGGTTTCTGAATGT GAGGGAGGAAGTCCTCCTGCATCTCAGGATAGCAATAAGGATGAACCTAAAAGTGGATTAAATGAAGACCAAGCCATGATGCAGGATTGT TACAGCAAAATTGTAGATAAGCTGTCCTCTGCAAACCCCACCATGGTATTACAGGTTCAGATGCTCGTGGCTGAACTGCGCAGGGTCACT GTGCTCTGGGATGAGCTCTGGCTGGGAGTTTTGCTGCAACAACACATGTATGTCCTGAGACGAATTCAGCAGCTTGAAGATGAGGTGAAG AGAGTCCAGAACAACAACACCTTACGCAAAGAAGAGAAAATTGCAATCATGAGGGAGAAGCACACAGCTTTGATGAAGCCCATCGTATTT GCTTTGGAGCATGTGAGGAGTATCACAGCGGCTCCTGCAGAAACACCTCATGAAAAATGGTTTCAGGATAACTATGGTGATGCCATTGAA AATGCCCTAGAAAAACTGAAGACTCCATTGAACCCTGCAAAGCCTGGGAGCAGCTGGATTCCATTTAAAGAGATAATGCTAAGTTTGCAA CAGAGAGCACAGAAACGTGCAAGTTACATCTTGCGTCTTGAAGAAATCAGTCCATGGTTGGCTGCCATGACTAACACTGAAATTGCTCTT CCTGGGGAAGTCTCAGCCAGAGACACTGTCACAATCCATAGTGTGGGCGGAACCATCACAATCTTACCGACTAAAACCAAGCCAAAGAAA CTTCTCTTTCTTGGATCAGATGGGAAGAGCTATCCTTATCTTTTCAAAGGACTGGAGGATTTACATCTGGATGAGAGAATAATGCAGTTC CTATCTATTGTGAATACCATGTTTGCTACAATTAATCGCCAAGAAACACCCCGGTTCCATGCTCGACACTATTCTGTAACACCACTAGGA ACAAGATCAGGACTAATCCAGTGGGTAGATGGAGCCACACCCTTATTTGGTCTTTACAAACGATGGCAACAACGGGAAGCTGCCTTACAA GCACAAAAGGCCCAAGATTCCTACCAAACTCCTCAGAATCCTGGAATTGTACCCCGTCCTAGTGAACTTTATTACAGTAAAATTGGCCCT GCTTTGAAAACAGTTGGGCTTAGCCTGGATGTGTCCCGTCGGGATTGGCCTCTTCATGTAATGAAGGCAGTATTGGAAGAGTTAATGGAG GCCACACCCCCGAATCTCCTTGCCAAAGAGCTCTGGTCATCTTGCACAACACCTGATGAATGGTGGAGAGTTACGCAGTCTTATGCAAGA TCTACTGCAGTCATGTCTATGGTTGGATACATAATTGGCCTTGGAGACAGACATCTGGATAATGTTCTTATAGATATGACGACTGGAGAA GTTGTTCACATAGATTACAATGTTTGCTTTGAAAAAGGTAAAAGCCTTAGAGTTCCTGAGAAAGTACCTTTTCGAATGACACAAAACATT GAAACAGCACTGGGTGTAACTGGAGTAGAAGGTGTATTTAGGCTTTCATGTGAGCAGGTTTTACACATTATGCGGCGTGGCAGAGAGACC CTGCTGACGCTGCTGGAGGCCTTTGTGTACGACCCTCTGGTGGACTGGACAGCAGGAGGCGAGGCTGGGTTTGCTGGTGCTGTCTATGGT GGAGGTGGCCAGCAGGCCGAGAGCAAGCAGAGCAAGAGAGAGATGGAGCGAGAGATCACCCGCAGCCTGTTTTCTTCTAGAGTAGCTGAG ATTAAGGTGAACTGGTTTAAGAATAGAGATGAGATGCTGGTTGTGCTTCCCAAGTTGGACGGTAGCTTAGATGAATACCTAAGCTTGCAA GAGCAACTGACAGATGTGGAAAAACTGCAGGGCAAACTACTGGAGGAAATAGAGTTTCTAGAAGGAGCTGAAGGGGTGGATCATCCTTCT CATACTCTGCAACACAGGTATTCTGAGCACACCCAACTACAGACTCAGCAAAGAGCTGTTCAGGAAGCAATCCAGGTGAAGCTGAATGAA TTTGAACAATGGATAACACATTATCAGGCTGCATTCAATAATTTAGAAGCAACACAGCTTGCAAGCTTGCTTCAAGAGATAAGCACACAA ATGGACCTTGGTCCTCCAAGTTACGTGCCAGCAACAGCCTTTCTGCAGAATGCTGGTCAGGCCCACTTGATTAGCCAGTGCGAGCAGCTG GAGGGGGAGGTTGGTGCTCTCCTGCAGCAGAGGCGCTCCGTGCTCCGTGGCTGTCTGGAGCAACTGCATCACTATGCAACCGTGGCCCTG CAGTATCCGAAGGCCATATTTCAGAAACATCGAATTGAACAGTGGAAGACCTGGATGGAAGAGCTCATCTGTAACACCACAGTAGAGCGT TGTCAAGAGCTCTATAGGAAATATGAAATGCAATATGCTCCCCAGCCACCCCCAACAGTGTGTCAGTTCATCACTGCCACTGAAATGACC CTGCAGCGATACGCAGCAGACATCAACAGCAGACTTATTAGACAAGTGGAACGCTTGAAACAGGAAGCTGTCACTGTGCCAGTTTGTGAA GATCAGTTGAAAGAAATTGAACGTTGCATTAAAGTTTTCCTTCATGAGAATGGAGAAGAAGGATCTTTGAGTCTAGCAAGTGTTATTATT TCTGCCCTTTGTACCCTTACAAGGCGTAACCTGATGATGGAAGGTGCAGCGTCAAGTGCTGGAGAACAGCTGGTTGATCTGACTTCTCGG GATGGAGCCTGGTTCTTGGAGGAACTCTGCAGTATGAGCGGAAACGTCACCTGCTTGGTTCAGTTACTGAAGCAGTGCCACCTGGTGCCA CAGGACTTAGATATCCCGAACCCCATGGAAGCGTCTGAGACAGTTCACTTAGCCAATGGAGTGTATACCTCACTTCAGGAATTGAATTCG AATTTCCGGCAAATCATATTTCCAGAAGCACTTCGATGTTTAATGAAAGGGGAATACACGTTAGAAAGTATGCTGCATGAACTGGACGGT CTTATTGAGCAGACCACCGATGGCGTTCCCCTGCAGACTCTAGTGGAATCTCTTCAGGCCTACTTAAGAAACGCAGCTATGGGACTGGAA GAAGAAACACATGCTCATTACATCGATGTTGCCAGACTACTACATGCTCAGTACGGTGAATTAATCCAACCGAGAAATGGTTCAGTTGAT GAAACACCCAAAATGTCAGCTGGCCAGATGCTTTTGGTAGCATTCGATGGCATGTTTGCTCAAGTTGAAACTGCTTTCAGCTTATTAGTT GAAAAGTTGAACAAGATGGAAATTCCCATAGCTTGGCGAAAGATTGACATCATAAGGGAAGCCAGGAGTACTCAAGTTAATTTTTTTGAT GATGATAATCACCGGCAGGTGCTAGAAGAGATTTTCTTTCTAAAAAGACTACAGACTATTAAGGAGTTCTTCAGGCTCTGTGGTACCTTT TCTAAAACATTGTCAGGATCAAGTTCACTTGAAGATCAGAATACTGTGAATGGGCCTGTACAGATTGTCAATGTGAAAACCCTTTTTAGA AACTCTTGTTTCAGTGAAGACCAAATGGCCAAACCTATCAAGGCATTCACAGCTGACTTTGTGAGGCAGCTCTTGATAGGGCTACCCAAC CAAGCCCTCGGACTCACACTGTGCAGTTTTATCAGTGCTCTGGGTGTAGACATCATTGCTCAAGTAGAGGCAAAGGACTTTGGTGCCGAA AGCAAAGTTTCTGTTGATGATCTCTGTAAGAAAGCGGTGGAACATAACATCCAGATAGGGAAGTTCTCTCAGCTGGTTATGAACAGGGCA ACTGTGTTAGCAAGTTCTTACGACACTGCCTGGAAGAAGCATGACTTGGTGCGAAGGCTAGAAACCAGTATTTCTTCTTGTAAGACAAGC CTGCAGCGGGTTCAGCTGCATATTGCCATGTTTCAGTGGCAACATGAAGATCTACTTATCAATAGACCACAAGCCATGTCAGTCACACCT CCCCCACGGTCTGCTATCCTAACCAGCATGAAAAAGAAGCTGCATACCCTGAGCCAGATTGAAACTTCTATTGCAACAGTTCAGGAGAAG CTAGCTGCACTTGAATCAAGTATTGAACAGCGACTCAAGTGGGCAGGTGGTGCCAACCCTGCATTGGCCCCTGTACTACAAGATTTTGAA GCAACGATAGCTGAAAGAAGAAATCTTGTCCTTAAAGAGAGCCAAAGAGCAAGTCAGGTCACATTTCTCTGCAGCAATATCATTCATTTT GAAAGTTTACGAACAAGAACTGCAGAAGCCTTAAACCTGGATGCGGCGTTATTTGAACTAATCAAGCGATGTCAGCAGATGTGTTCGTTT GCATCACAGTTTAACAGTTCAGTGTCTGAGTTAGAGCTTCGTTTATTACAGAGAGTGGACACTGGTCTTGAACATCCTATTGGCAGCTCT GAATGGCTTTTGTCAGCACACAAACAGTTGACCCAGGATATGTCTACTCAGAGGGCAATTCAGACAGAGAAAGAGCAGCAGATAGAAACG GTCTGTGAAACAATTCAGAATCTGGTTGATAATATAAAGACTGTGCTCACTGGTCATAACCGACAGCTTGGAGATGTCAAACATCTCTTG AAAGCTATGGCTAAGGATGAAGAAGCTGCTCTGGCAGATGGTGAAGATGTTCCCTATGAGAACAGTGTTAGGCAGTTTTTGGGTGAATAT AAATCATGGCAAGACAACATTCAAACAGTTCTATTTACATTAGTCCAGGCTATGGGTCAGGTTCGAAGTCAAGAACACGTTGAAATGCTC CAGGAAATCACTCCCACCTTGAAAGAACTGAAAACACAAAGTCAGAGTATCTATAATAATTTAGTGAGTTTTGCATCACCCTTAGTCACC GATGCAACAAATGAATGTTCGAGTCCAACGTCATCTGCTACTTATCAGCCATCCTTCGCTGCAGCAGTCCGGAGTAACACTGGCCAGAAG ACTCAGCCTGATGTCATGTCACAGAATGCTAGAAAGCTGATCCAAAAAAATCTTGCTACATCAGCTGATACTCCACCAAGCACCGTTCCA GGAACTGGCAAGAGTGTTGCTTGTAGTCCTAAAAAGGCAGTCAGAGACCCTAAAACTGGGAAAGCGGTGCAAGAGAGAAACTCCTATGCA GTGAGTGTGTGGAAGAGAGTGAAAGCCAAGTTAGAGGGCCGAGATGTTGATCCGAATAGGAGGATGTCAGTTGCTGAACAGGTTGACTAT GTCATTAAGGAAGCAACTAATCTAGATAACTTGGCTCAGCTGTATGAAGGTTGGACAGCCTGGGTGTGAATGGCAAGACAGTAGATGAGT CTGGTTAAGCGAGGTCAGACATCCACCAGAATCAACTCAGCCTCAGGCATCCAAAGCCACACCACAGTCGGTGGTGATGCAACTGGGGGC TTACTCTGAGGAAACCTAGGAAATCTCGGTGCACTAGGAAGTGAATCCCGCAGGACAGCTGCACTCAGGGATACGCCCAACACCATGGCC TGCAACCCCAGGGTCAAGGGTGAAGGAAAGCAAGCTCACCGCCTGAACACGGAGATTGTCTTTCTGCCACAGAACAGCAGCAGACGTGTC GGGAGGTTAGCTGCGGAAAGAAATCGGGATGCCGCGGAGCACAGAGTGATTTGGAACTCCATTCCACCTGACCCTGTGTGTACAATCCAG GAAAAAAACAAACCCCACTCAGAAACAGAGAAAACTGGGGTCGCGAAGAAATCACAGCCAAGGAAGATTTGATGCATTCAGATTCTCGTG TAACACTTGTTGCTTGGCAACAGTACTGGTTGGGTTGACCAGTAAGTAGAAAAAGGCTAAAGGCTATGCGATATGAATTTCAGAAATGGA CTGAAAATGGAGAGCTATGTAACAGATACACTACAGTAGAAGAACTTACTTCTGAAATGAAGGGAAAAAAACCACCCCATCGTTCCCTAC TCCTCCCCACCACTTACCCGTTCCCCCTTTACCTAATCTAGTAGATTAGCCATCTTTCAAATTCACTTTTATTTCAGTCCTTATATTTCA TATACTTCCGTCTCGATGCTGTTAACAACTTCTGATAACATGGAAAATTCAAGGATTGTTTAAAGGTCTGATGATCACACACAAAATGTA ATTCCGGTTATTTAAGTCATTTCTGTGATTCTATCATGTACAGTTTCCAGAATTGTCACTGTGCATTCAAAAGTAATGAATCTAACAGAC ATTTGATTTAATGTACACTCCCTTTTGCTTATAGTGTGCATTTTTTTTGGAGGTCATTCAAATTTTCCCTCTTCTGTGATAGCTGTAGTT TCTTTCATAGAAAGTAGCTAATCCAGTGTAATCTTTTACCTTTTTAAAAACCAAGATAGAGTATCTATTAGAGTTTTACATTGTTGATGA TAGATTAACAATAAAGTGATGTTCTGGTGGAGGTAGACTGAAATTTTTTTAATTCATGTTTTTCATTTGATACTTTTAATTTACACTTAG TAAATTAAAAGTTGTTTAATTTACTTGGCATTTTAGGACATGTACATGAAACAGTGAAAATGAGATCCACCAACATCTTTTATTAAGTTC AGTTATTAGTCTGTGAAGTGCTTTACTTTTTGCACAATTTTAATAGCTTGCTATTCAGTAATACATTATAGTGAATTCATGATCAAGGTT TCCTTAAATTTAGCATTGCATTTCAGTACTGACTGTGTAAGCTAAATTGCTGATCCAAAATAAAAACCCAGACTAGAATAGGGTTCTTAA AATCAAGTATCAATACAAAATAGAACACAATTAAAATCTTAATTGTTGGCTGGGCACAGTGGCTCACGCCTGTAATCCCAGCACTTTGGG AGGCCGAGGCGGGCGGATCATGAGGTTAGGAGAGCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTTTACTAAAAATACAAAAAAA ATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGGAGGCGGAGCTTG CAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAGAGCTAGACTCTGTGTCAAAAATAAATGACTAGATAAAAAAAAAAAT TGTTTGAGTACATTTTCCCTGCATTTTAGAGATTAGGACAGTGGTCACTTTCTAGTTGCCGTCTTCACAGACAAACTTGAAAGGTATTAA GGAAAAAATTCCACATAGCTCTGGGCCTTTTTTGTATTCTGATTGCCACGTTAATCTGTAATCGTTAAGTACCCATGAAAGAATGTGTTT CAGTATCAGTGCTTTTTTGGTACTTTAACAAGTATTGTAGGCACGGTGGATTTTTTTGAAATACCCATGTGTCCAATAGCAAGTTAAGGA ACCTAGCGCATCAAATTTTGTTTTCTTCATTCATTTGGAACCTTATTTTCGCAAAAAACCTAGCTGGAATAATAATGCCATATTGTATTT TGCACACTGCTTTATTTTCTAGAGGCTCTGGGAGCAAATTACATTCATCACATTACCTCTGCTCTCTCAAGATTAAAGTCTTTCAGCAAC ATTCTTTATTGTCATCATAAGGAAAAACTTTTATCGCAATGATAGTCAGTTCACATTAGTTTAGCACTATAGATAGTATTCAGAAATTGC TTTCTCTTTGGTAAAGAAGATAAATAGGTGAATTTTATTGCCTGTGTTTTCAGGCTTCAGAGGTACCTGGCACCTTACTCAAGCAAAAAC AAAAAACAGCTTTACTTCAAAAGCATGTGCCTCTGGTAAATTATCCATCACTTTTGTTTTAAAGTGGTCCCTCCAAGAATAATGTGGCAT ACACAGTGGGTTTGGTTGTAAGGCAGATGTAATAGATGACTTCAAAAGCCTGCTCCTTACTGCACTCTGGACAAGGCCCTGGTCTGTATA GTTTGGCTTCCTCTGTTAAGTCATTCTACAAGGTGACTTGCCATTTGAACTTTCGTAAGAGACCTCAGCAGTTAGACTGAGAAAAGTTAG AGTGCTGTAGTTATGAAGTCATACATTTTTGATAAAATACCTGTGGAAAACCAGGGATCCTCTCCTGTTTCTCTCTCTTGCCTCCCCCTT TCCCTCCATTCCTCTGTCGCCTCCCCCTCTCCTCCACTTTCTTTAAGAATCAGGGGGTACAGAATAACCTACAAACAACCTCTTCAAAGT ACCCTTGGAAATTGAAGTTCAATCTTAAGTTTTTTGCTGTCTTTAATTTACTAGAATTGCCTAATTTTTAGTTGATTTCTCTACAGAGCT TAGCTTGTGTAGTTATTTCTCTTTTACTGTTGCTTTGGTGTGTCTTGAAGTTTGATTGATTATTTTTGGTCATTGAGTTCTTAGTGTAGT TTGCTAGATGATTATTAAGATTCTTTTGTGTCTGACACTTGTGGTGAGTTGCTTTTGAAATCTGTTGAGATTTCCATGTGAGAACTGATA ATCAGGCTCTTGATCTGCTTCCCTAAATTACTTTTTTAGAGCCCAAACCCCAGGTTTAGGGTGAGGGTTTGTAATACAAAGAAACACTTC CATCACTTCTGCCCTTAACCCTTGCCTCTATTACCTAAGCTTAGTAAGTAGTTTTCTTAATATTGTCCAATGTTTGGTGTTATCTGCATT GTTTTTTGTTTTTTTAATTGTGGTTGTTCTGACGTGTGAAATTTAAGGAAAGAGCCATTTTTTAAAAATGCCGAGCAGGGCAATGCAAGT ACAGCCAAATATTAGACTTGATGTGCAATCTTCGGTCCTTTTTAATCTGGGGTATTATAGGCAGTACTTTAAATTGCAAAGTCTTCCGGG CCTATTTTCCTCTACATTTTTGTAATTAACTCTGGGGGCTTACTTGTTTTGGCAGTACTGAAATCAAAGGAGCTGGTTCTTCTTTTCTCC CAATTATTTTCATATGAAAGCACCTACAATTAGCCTGTTAGTCCTATTCAGATACATCAAATATCAGTGAATGCTTTACTATTCGCACAT TTAAGCATCTTTGTTTTACATAAAATTAGAGTATGAAAACCAGTGTTCAATTTTTTATCTTGTTGAGCTTGTAAAATGCCAGCAATTTAA AACTAGGACTTTTCCCCCCATAAGCCAAGGAGGTAGAATTACTAATACAAGGGTTAAAGAAGGTAGATTTTGTTTTCAATATTTGGGTAA TATTAGAAAGATTCTTCCCACAGGGAAGAACTAGCAAGTGTCCCAATTTTTTCCAAACGTTGGGGAGGGGAAAATTCACTGTATCATGAA ACCCTAAGGGTTTGTTGCACTTCCTGCTTTTTAGGCCTGGATAACAGTATCACCATCCTTATTTACAGAAGGGTAAAACTGACTCTTAAT GAGAAAAGCTTTATAAGTTCAAGGGCTGTAAAATATGAACTACTTAGGGTCGTTTGCCTTCCATGGGAACTTGGCTAGACTTAGAAAAAG CTGTTTGTTGTGCTAATGTAAAAGTGTCATACAATTTAGAAGATTTTTGAAGATGGTAAACTTAGAAGAATTCTATGTTCTGAAATGCAC ACTTTTAGAATGTTTTTCTTTGAAAACAGGCTAATAGTTTTTTCTTTTTTTGACAAAGTTTCAGCTCCTCTTTAAAGTTATTGTGTCATT TTTCTGGTTTAAATTTCCCTTATATTTCCACCTGTAATGTCAGTGGCAACAACATCATACTTCACTTACTTGTTAATTTACTTTTTACCC TTATTCTAAGAGCAAGTTGAGTTGAACTGAATCTTCCTTGTCTTAGTAACAATGTATAAATAGTGGCTTTTCTGTACAAAAGGTTGTAAT GCCTCCTGATGGATATAATTTTGTGATTGTATTTAAAAGTTGAATAAATCACACCAGCTTCCTGAAAATGTTCATAATGCATCTTTTGGA AAACAAATACATGCCTACTTTGTGCATATTTGCATTAACATGGCAAAGATTGTATGAAATACCTGTTTTTCAGAAAATAAAGGTTCAGTC >95597_95597_2_TXNL4B-SMG1_TXNL4B_chr16_72122885_ENST00000423037_SMG1_chr16_18891041_ENST00000446231_length(amino acids)=3229AA_BP=1 MYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPSMTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEK LFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPVLETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVI FDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTA TKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPD DLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNW LERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEG HGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTS LSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANA GRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKF VECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAI GPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKEQTVPIRSHLM ELGLTAAKFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQSTHAMEMLSSCAISFC KSVKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLSTLSKNILTLIELPSVNTMEEEYPRIESESTVHIGVGEPDFILG QLYHLSSVQAPEVAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQAVCRPAGIQDEDITLQI TESEDNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQIPLDEDDPRLHLSHRVEQSTD DMIVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLILYPAIVGTISLSSESQ ASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLW DELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWFQDNYGDAIENAL EKLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKPKKLLF LGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQK AQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTA VMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLT LLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVLPKLDGSLDEYLSLQEQL TDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRYSEHTQLQTQQRAVQEAIQVKLNEFEQWITHYQAAFNNLEATQLASLLQEISTQMDL GPPSYVPATAFLQNAGQAHLISQCEQLEGEVGALLQQRRSVLRGCLEQLHHYATVALQYPKAIFQKHRIEQWKTWMEELICNTTVERCQE LYRKYEMQYAPQPPPTVCQFITATEMTLQRYAADINSRLIRQVERLKQEAVTVPVCEDQLKEIERCIKVFLHENGEEGSLSLASVIISAL CTLTRRNLMMEGAASSAGEQLVDLTSRDGAWFLEELCSMSGNVTCLVQLLKQCHLVPQDLDIPNPMEASETVHLANGVYTSLQELNSNFR QIIFPEALRCLMKGEYTLESMLHELDGLIEQTTDGVPLQTLVESLQAYLRNAAMGLEEETHAHYIDVARLLHAQYGELIQPRNGSVDETP KMSAGQMLLVAFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREARSTQVNFFDDDNHRQVLEEIFFLKRLQTIKEFFRLCGTFSKT LSGSSSLEDQNTVNGPVQIVNVKTLFRNSCFSEDQMAKPIKAFTADFVRQLLIGLPNQALGLTLCSFISALGVDIIAQVEAKDFGAESKV SVDDLCKKAVEHNIQIGKFSQLVMNRATVLASSYDTAWKKHDLVRRLETSISSCKTSLQRVQLHIAMFQWQHEDLLINRPQAMSVTPPPR SAILTSMKKKLHTLSQIETSIATVQEKLAALESSIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQRASQVTFLCSNIIHFESL RTRTAEALNLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDTGLEHPIGSSEWLLSAHKQLTQDMSTQRAIQTEKEQQIETVCE TIQNLVDNIKTVLTGHNRQLGDVKHLLKAMAKDEEAALADGEDVPYENSVRQFLGEYKSWQDNIQTVLFTLVQAMGQVRSQEHVEMLQEI TPTLKELKTQSQSIYNNLVSFASPLVTDATNECSSPTSSATYQPSFAAAVRSNTGQKTQPDVMSQNARKLIQKNLATSADTPPSTVPGTG -------------------------------------------------------------- >95597_95597_3_TXNL4B-SMG1_TXNL4B_chr16_72122885_ENST00000423037_SMG1_chr16_18891041_ENST00000565224_length(transcript)=1659nt_BP=546nt ACGCCCGATTCCTGGATCCAAGTGTGGAACGGTACGCCAACAGGCTCTCAAGGCCTCCTCTGGGGCTCTGATCAGACACTTCCGAGTCTC CTTGTGACCAATCACTCTTAGCCTAAGAGACTACATCCCGCCTCTAGTCTGGGGGCAGGAAAAGGAGGGGAAAAAGGTCGACCATCTTTA ATACGGGCGGAGGTGACGCCTAGCTTCCGGTCAGAGCCGAGCAAGGAGTGACAGTGAGGATTCACATTTGGGTTATTTCAAGATGAGCTT CCTACTGCCCAAGCTGACTAGCAAAAAGGAAGTAGACCAGGCGATAAAAAGTACTGCTGAGAAGGTGTTGGTTCTCAGGTTTGGGAGAGA TGAAGATCCTGTCTGTCTGCAGCTAGATGATATTCTTTCTAAGACCTCTTCTGACTTAAGTAAAATGGCTGCTATATACCTGGTAGATGT GGACCAAACTGCAGTTTATACACAGTATTTTGACATCAGTTATATTCCATCTACTGTCTTTTTCTTCAATGGGCAGCATATGAAAGTGGA TTATGGGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAGGCTGTGTTGACAGCTGCTAATGAGTGT GTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACATATGGATTAGACCAACTGGAGAATTGC CAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAGATAAATACGAAACTGCCATCATCATTT GTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAGGTTGTTGCTGTAGCCCATGCTGTTTAT CAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGAGAAATGACTTGTGCCCTAAACAACCTC CTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCATGTGTTCAATGTAGACAATGCAAAATTT GTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGGGTGAGTCTTTAATTGTAATGACTTTGT TTTATCCACAGTTAAGCCTTTTCTCATTACATATTTATGTATTTCACTGTCATGTCAAGATGTCTGCAGAATCACTGTGTGTAACAAACA GCCATATTTAAGACATGCCTGGATAAATAAAATTGGTAGGAATGTTTTCTTGGCATTATATTTAACTTTTCTTCTTCTTTTTCCTTGACA AATCTTGATAAGTTTTTTTATATTAGTTTTATTTTCTAGAAAATGTCTTATGAATTTCTCCTATTTGCTCTAGCATGCTTATAGAAAATG TCAGTGTTTCTTACAGCTCAAATTTGTGTAGTTGTTTTAAAATGCGGTCTCTTTCTTCTTCCCCTGGTACTTTTTTCTTTCTGTCTACTG AAGTTAGTTCTTATACATGGTCTTATATTTTGGCTGTCTCTTTTCCCTAGGAACATTCATACAGGTTGAATATTCCTTATCTGAAATACT >95597_95597_3_TXNL4B-SMG1_TXNL4B_chr16_72122885_ENST00000423037_SMG1_chr16_18891041_ENST00000565224_length(amino acids)=201AA_BP=1 MYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPSMTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEK LFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPVLETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVI -------------------------------------------------------------- >95597_95597_4_TXNL4B-SMG1_TXNL4B_chr16_72122885_ENST00000426362_SMG1_chr16_18891041_ENST00000389467_length(transcript)=14971nt_BP=559nt GAGATCGCCCACCAGATTGCCTGGTATAAATGACACTGTGAGAGAGCAGAGGAAGACACAAGGAGTCCTACTCGGGCTCGGTGACAGTCT GGGGTGGGTTAAAGCGGAGGCCTGGGAGAGGGACCAAGGCCACTCCAGGCAGCATCCCTGGATCTCAGCGAGGCCGCTCCAGGCAGCAGG ATTTGACCAGAGCAAGGAGGAAGGCCAAGGCGGCCAGGACGGATGCAGCATCCCTGAGGAGTGACAGTGAGGATTCACATTTGGGTTATT TCAAGATGAGCTTCCTACTGCCCAAGCTGACTAGCAAAAAGGAAGTAGACCAGGCGATAAAAAGTACTGCTGAGAAGGTGTTGGTTCTCA GGTTTGGGAGAGATGAAGATCCTGTCTGTCTGCAGCTAGATGATATTCTTTCTAAGACCTCTTCTGACTTAAGTAAAATGGCTGCTATAT ACCTGGTAGATGTGGACCAAACTGCAGTTTATACACAGTATTTTGACATCAGTTATATTCCATCTACTGTCTTTTTCTTCAATGGGCAGC ATATGAAAGTGGATTATGGGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAGGCTGTGTTGACAGC TGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACATATGGATTAGACCA ACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAGATAAATACGAAACT GCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAGGTTGTTGCTGTAGC CCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGAGAAATGACTTGTGC CCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCATGTGTTCAATGTAGA CAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGGATGTGGGCGCTATC TCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCT CTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGT GATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCA GGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCC GTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGC TCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACA AGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATT AAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCA TAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCT CCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAG AGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGAC AACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTA TAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGA CTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCT TACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTG TCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGA AGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATC GGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACC GACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGA ATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAG CAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAA AGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAG AAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAA GCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTA TTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATG TAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGAACAAACAGT CCCAATTAGAAGCCATCTCATGGAATTAGGTCTAACAGCAGCAAAATTTGCTAGAAAACGAGGGAATGTGTCCCTTGCAACAAGACTGCT GGCACAGTGCAGTGAAGTTCAGCTGGGAAAGACCACCACTGCACAGGATTTAGTCCAACATTTTAAAAAACTATCAACCCAAGGTCAAGT GGATGAAAAATGGGGGCCCGAACTTGATATTGAAAAAACCAAATTGCTTTATACAGCAGGCCAGTCAACACATGCAATGGAAATGTTGAG TTCTTGTGCCATATCTTTCTGCAAGTCTGTGAAAGCTGAATATGCAGTTGCTAAATCAATTCTGACACTGGCTAAATGGATCCAGGCAGA ATGGAAAGAGATTTCAGGACAGCTGAAACAGGTTTACAGAGCTCAGCACCAACAGAACTTCACAGGTCTTTCTACTTTGTCTAAAAACAT ACTCACTCTAATAGAACTGCCATCTGTTAATACGATGGAAGAAGAGTATCCTCGGATCGAGAGTGAATCTACAGTGCATATTGGAGTTGG AGAACCTGACTTCATTTTGGGACAGTTGTATCACCTGTCTTCAGTACAGGCACCTGAAGTAGCCAAATCTTGGGCAGCGTTGGCCAGCTG GGCTTATAGGTGGGGCAGAAAGGTGGTTGACAATGCCAGTCAGGGAGAAGGTGTTCGTCTGCTGCCTAGAGAAAAATCTGAAGTTCAGAA TCTACTTCCAGACACTATAACTGAGGAAGAGAAAGAGAGAATATATGGTATTCTTGGACAGGCTGTGTGTCGGCCGGCGGGGATTCAGGA TGAAGATATAACACTTCAGATAACTGAGAGTGAAGACAACGAAGAAGATGACATGGTTGATGTTATCTGGCGTCAGTTGATATCAAGCTG CCCATGGCTTTCAGAACTTGATGAAAGTGCAACTGAAGGAGTTATTAAAGTGTGGAGGAAAGTTGTAGATAGAATATTCAGCCTGTACAA ACTCTCTTGCAGTGCATACTTTACTTTCCTTAAACTCAACGCTGGTCAAATTCCTTTAGATGAGGATGACCCTAGGCTGCATTTAAGTCA CAGAGTGGAACAGAGCACTGATGACATGATTGTGATGGCCACATTGCGCCTGCTGCGGTTGCTCGTGAAGCATGCTGGTGAGCTTCGGCA GTATCTGGAGCACGGCTTGGAGACAACACCCACTGCACCATGGAGAGGAATTATTCCGCAACTTTTCTCACGCTTAAACCACCCTGAAGT GTATGTGCGCCAAAGTATTTGTAACCTTCTCTGCCGTGTGGCTCAAGATTCCCCACATCTCATATTGTATCCTGCAATAGTGGGTACCAT ATCGCTTAGTAGTGAATCCCAGGCTTCAGGAAATAAATTTTCCACTGCAATTCCAACTTTACTTGGCAATATTCAAGGAGAAGAATTGCT GGTTTCTGAATGTGAGGGAGGAAGTCCTCCTGCATCTCAGGATAGCAATAAGGATGAACCTAAAAGTGGATTAAATGAAGACCAAGCCAT GATGCAGGATTGTTACAGCAAAATTGTAGATAAGCTGTCCTCTGCAAACCCCACCATGGTATTACAGGTTCAGATGCTCGTGGCTGAACT GCGCAGGGTCACTGTGCTCTGGGATGAGCTCTGGCTGGGAGTTTTGCTGCAACAACACATGTATGTCCTGAGACGAATTCAGCAGCTTGA AGATGAGGTGAAGAGAGTCCAGAACAACAACACCTTACGCAAAGAAGAGAAAATTGCAATCATGAGGGAGAAGCACACAGCTTTGATGAA GCCCATCGTATTTGCTTTGGAGCATGTGAGGAGTATCACAGCGGCTCCTGCAGAAACACCTCATGAAAAATGGTTTCAGGATAACTATGG TGATGCCATTGAAAATGCCCTAGAAAAACTGAAGACTCCATTGAACCCTGCAAAGCCTGGGAGCAGCTGGATTCCATTTAAAGAGATAAT GCTAAGTTTGCAACAGAGAGCACAGAAACGTGCAAGTTACATCTTGCGTCTTGAAGAAATCAGTCCATGGTTGGCTGCCATGACTAACAC TGAAATTGCTCTTCCTGGGGAAGTCTCAGCCAGAGACACTGTCACAATCCATAGTGTGGGCGGAACCATCACAATCTTACCGACTAAAAC CAAGCCAAAGAAACTTCTCTTTCTTGGATCAGATGGGAAGAGCTATCCTTATCTTTTCAAAGGACTGGAGGATTTACATCTGGATGAGAG AATAATGCAGTTCCTATCTATTGTGAATACCATGTTTGCTACAATTAATCGCCAAGAAACACCCCGGTTCCATGCTCGACACTATTCTGT AACACCACTAGGAACAAGATCAGGACTAATCCAGTGGGTAGATGGAGCCACACCCTTATTTGGTCTTTACAAACGATGGCAACAACGGGA AGCTGCCTTACAAGCACAAAAGGCCCAAGATTCCTACCAAACTCCTCAGAATCCTGGAATTGTACCCCGTCCTAGTGAACTTTATTACAG TAAAATTGGCCCTGCTTTGAAAACAGTTGGGCTTAGCCTGGATGTGTCCCGTCGGGATTGGCCTCTTCATGTAATGAAGGCAGTATTGGA AGAGTTAATGGAGGCCACACCCCCGAATCTCCTTGCCAAAGAGCTCTGGTCATCTTGCACAACACCTGATGAATGGTGGAGAGTTACGCA GTCTTATGCAAGATCTACTGCAGTCATGTCTATGGTTGGATACATAATTGGCCTTGGAGACAGACATCTGGATAATGTTCTTATAGATAT GACGACTGGAGAAGTTGTTCACATAGATTACAATGTTTGCTTTGAAAAAGGTAAAAGCCTTAGAGTTCCTGAGAAAGTACCTTTTCGAAT GACACAAAACATTGAAACAGCACTGGGTGTAACTGGAGTAGAAGGTGTATTTAGGCTTTCATGTGAGCAGGTTTTACACATTATGCGGCG TGGCAGAGAGACCCTGCTGACGCTGCTGGAGGCCTTTGTGTACGACCCTCTGGTGGACTGGACAGCAGGAGGCGAGGCTGGGTTTGCTGG TGCTGTCTATGGTGGAGGTGGCCAGCAGGCCGAGAGCAAGCAGAGCAAGAGAGAGATGGAGCGAGAGATCACCCGCAGCCTGTTTTCTTC TAGAGTAGCTGAGATTAAGGTGAACTGGTTTAAGAATAGAGATGAGATGCTGGTTGTGCTTCCCAAGTTGGACGGTAGCTTAGATGAATA CCTAAGCTTGCAAGAGCAACTGACAGATGTGGAAAAACTGCAGGGCAAACTACTGGAGGAAATAGAGTTTCTAGAAGGAGCTGAAGGGGT GGATCATCCTTCTCATACTCTGCAACACAGGTATTCTGAGCACACCCAACTACAGACTCAGCAAAGAGCTGTTCAGGAAGCAATCCAGGT GAAGCTGAATGAATTTGAACAATGGATAACACATTATCAGGCTGCATTCAATAATTTAGAAGCAACACAGCTTGCAAGCTTGCTTCAAGA GATAAGCACACAAATGGACCTTGGTCCTCCAAGTTACGTGCCAGCAACAGCCTTTCTGCAGAATGCTGGTCAGGCCCACTTGATTAGCCA GTGCGAGCAGCTGGAGGGGGAGGTTGGTGCTCTCCTGCAGCAGAGGCGCTCCGTGCTCCGTGGCTGTCTGGAGCAACTGCATCACTATGC AACCGTGGCCCTGCAGTATCCGAAGGCCATATTTCAGAAACATCGAATTGAACAGTGGAAGACCTGGATGGAAGAGCTCATCTGTAACAC CACAGTAGAGCGTTGTCAAGAGCTCTATAGGAAATATGAAATGCAATATGCTCCCCAGCCACCCCCAACAGTGTGTCAGTTCATCACTGC CACTGAAATGACCCTGCAGCGATACGCAGCAGACATCAACAGCAGACTTATTAGACAAGTGGAACGCTTGAAACAGGAAGCTGTCACTGT GCCAGTTTGTGAAGATCAGTTGAAAGAAATTGAACGTTGCATTAAAGTTTTCCTTCATGAGAATGGAGAAGAAGGATCTTTGAGTCTAGC AAGTGTTATTATTTCTGCCCTTTGTACCCTTACAAGGCGTAACCTGATGATGGAAGGTGCAGCGTCAAGTGCTGGAGAACAGCTGGTTGA TCTGACTTCTCGGGATGGAGCCTGGTTCTTGGAGGAACTCTGCAGTATGAGCGGAAACGTCACCTGCTTGGTTCAGTTACTGAAGCAGTG CCACCTGGTGCCACAGGACTTAGATATCCCGAACCCCATGGAAGCGTCTGAGACAGTTCACTTAGCCAATGGAGTGTATACCTCACTTCA GGAATTGAATTCGAATTTCCGGCAAATCATATTTCCAGAAGCACTTCGATGTTTAATGAAAGGGGAATACACGTTAGAAAGTATGCTGCA TGAACTGGACGGTCTTATTGAGCAGACCACCGATGGCGTTCCCCTGCAGACTCTAGTGGAATCTCTTCAGGCCTACTTAAGAAACGCAGC TATGGGACTGGAAGAAGAAACACATGCTCATTACATCGATGTTGCCAGACTACTACATGCTCAGTACGGTGAATTAATCCAACCGAGAAA TGGTTCAGTTGATGAAACACCCAAAATGTCAGCTGGCCAGATGCTTTTGGTAGCATTCGATGGCATGTTTGCTCAAGTTGAAACTGCTTT CAGCTTATTAGTTGAAAAGTTGAACAAGATGGAAATTCCCATAGCTTGGCGAAAGATTGACATCATAAGGGAAGCCAGGAGTACTCAAGT TAATTTTTTTGATGATGATAATCACCGGCAGGTGCTAGAAGAGATTTTCTTTCTAAAAAGACTACAGACTATTAAGGAGTTCTTCAGGCT CTGTGGTACCTTTTCTAAAACATTGTCAGGATCAAGTTCACTTGAAGATCAGAATACTGTGAATGGGCCTGTACAGATTGTCAATGTGAA AACCCTTTTTAGAAACTCTTGTTTCAGTGAAGACCAAATGGCCAAACCTATCAAGGCATTCACAGCTGACTTTGTGAGGCAGCTCTTGAT AGGGCTACCCAACCAAGCCCTCGGACTCACACTGTGCAGTTTTATCAGTGCTCTGGGTGTAGACATCATTGCTCAAGTAGAGGCAAAGGA CTTTGGTGCCGAAAGCAAAGTTTCTGTTGATGATCTCTGTAAGAAAGCGGTGGAACATAACATCCAGATAGGGAAGTTCTCTCAGCTGGT TATGAACAGGGCAACTGTGTTAGCAAGTTCTTACGACACTGCCTGGAAGAAGCATGACTTGGTGCGAAGGCTAGAAACCAGTATTTCTTC TTGTAAGACAAGCCTGCAGCGGGTTCAGCTGCATATTGCCATGTTTCAGCAGTGGCAACATGAAGATCTACTTATCAATAGACCACAAGC CATGTCAGTCACACCTCCCCCACGGTCTGCTATCCTAACCAGCATGAAAAAGAAGCTGCATACCCTGAGCCAGATTGAAACTTCTATTGC AACAGTTCAGGAGAAGCTAGCTGCACTTGAATCAAGTATTGAACAGCGACTCAAGTGGGCAGGTGGTGCCAACCCTGCATTGGCCCCTGT ACTACAAGATTTTGAAGCAACGATAGCTGAAAGAAGAAATCTTGTCCTTAAAGAGAGCCAAAGAGCAAGTCAGGTCACATTTCTCTGCAG CAATATCATTCATTTTGAAAGTTTACGAACAAGAACTGCAGAAGCCTTAAACCTGGATGCGGCGTTATTTGAACTAATCAAGCGATGTCA GCAGATGTGTTCGTTTGCATCACAGTTTAACAGTTCAGTGTCTGAGTTAGAGCTTCGTTTATTACAGAGAGTGGACACTGGTCTTGAACA TCCTATTGGCAGCTCTGAATGGCTTTTGTCAGCACACAAACAGTTGACCCAGGATATGTCTACTCAGAGGGCAATTCAGACAGAGAAAGA GCAGCAGATAGAAACGGTCTGTGAAACAATTCAGAATCTGGTTGATAATATAAAGACTGTGCTCACTGGTCATAACCGACAGCTTGGAGA TGTCAAACATCTCTTGAAAGCTATGGCTAAGGATGAAGAAGCTGCTCTGGCAGATGGTGAAGATGTTCCCTATGAGAACAGTGTTAGGCA GTTTTTGGGTGAATATAAATCATGGCAAGACAACATTCAAACAGTTCTATTTACATTAGTCCAGGCTATGGGTCAGGTTCGAAGTCAAGA ACACGTTGAAATGCTCCAGGAAATCACTCCCACCTTGAAAGAACTGAAAACACAAAGTCAGAGTATCTATAATAATTTAGTGAGTTTTGC ATCACCCTTAGTCACCGATGCAACAAATGAATGTTCGAGTCCAACGTCATCTGCTACTTATCAGCCATCCTTCGCTGCAGCAGTCCGGAG TAACACTGGCCAGAAGACTCAGCCTGATGTCATGTCACAGAATGCTAGAAAGCTGATCCAAAAAAATCTTGCTACATCAGCTGATACTCC ACCAAGCACCGTTCCAGGAACTGGCAAGAGTGTTGCTTGTAGTCCTAAAAAGGCAGTCAGAGACCCTAAAACTGGGAAAGCGGTGCAAGA GAGAAACTCCTATGCAGTGAGTGTGTGGAAGAGAGTGAAAGCCAAGTTAGAGGGCCGAGATGTTGATCCGAATAGGAGGATGTCAGTTGC TGAACAGGTTGACTATGTCATTAAGGAAGCAACTAATCTAGATAACTTGGCTCAGCTGTATGAAGGTTGGACAGCCTGGGTGTGAATGGC AAGACAGTAGATGAGTCTGGTTAAGCGAGGTCAGACATCCACCAGAATCAACTCAGCCTCAGGCATCCAAAGCCACACCACAGTCGGTGG TGATGCAACTGGGGGCTTACTCTGAGGAAACCTAGGAAATCTCGGTGCACTAGGAAGTGAATCCCGCAGGACAGCTGCACTCAGGGATAC GCCCAACACCATGGCCTGCAACCCCAGGGTCAAGGGTGAAGGAAAGCAAGCTCACCGCCTGAACACGGAGATTGTCTTTCTGCCACAGAA CAGCAGCAGACGTGTCGGGAGGTTAGCTGCGGAAAGAAATCGGGATGCCGCGGAGCACAGAGTGATTTGGAACTCCATTCCACCTGACCC TGTGTGTACAATCCAGGAAAAAAACAAACCCCACTCAGAAACAGAGAAAACTGGGGTCGCGAAGAAATCACAGCCAAGGAAGATTTGATG CATTCAGATTCTCGTGTAACACTTGTTGCTTGGCAACAGTACTGGTTGGGTTGACCAGTAAGTAGAAAAAGGCTAAAGGCTATGCGATAT GAATTTCAGAAATGGACTGAAAATGGAGAGCTATGTAACAGATACACTACAGTAGAAGAACTTACTTCTGAAATGAAGGGAAAAAAACCA CCCCATCGTTCCCTACTCCTCCCCACCACTTACCCGTTCCCCCTTTACCTAATCTAGTAGATTAGCCATCTTTCAAATTCACTTTTATTT CAGTCCTTATATTTCATATACTTCCGTCTCGATGCTGTTAACAACTTCTGATAACATGGAAAATTCAAGGATTGTTTAAAGGTCTGATGA TCACACACAAAATGTAATTCCGGTTATTTAAGTCATTTCTGTGATTCTATCATGTACAGTTTCCAGAATTGTCACTGTGCATTCAAAAGT AATGAATCTAACAGACATTTGATTTAATGTACACTCCCTTTTGCTTATAGTGTGCATTTTTTTTGGAGGTCATTCAAATTTTCCCTCTTC TGTGATAGCTGTAGTTTCTTTCATAGAAAGTAGCTAATCCAGTGTAATCTTTTACCTTTTTAAAAACCAAGATAGAGTATCTATTAGAGT TTTACATTGTTGATGATAGATTAACAATAAAGTGATGTTCTGGTGGAGGTAGACTGAAATTTTTTTAATTCATGTTTTTCATTTGATACT TTTAATTTACACTTAGTAAATTAAAAGTTGTTTAATTTACTTGGCATTTTAGGACATGTACATGAAACAGTGAAAATGAGATCCACCAAC ATCTTTTATTAAGTTCAGTTATTAGTCTGTGAAGTGCTTTACTTTTTGCACAATTTTAATAGCTTGCTATTCAGTAATACATTATAGTGA ATTCATGATCAAGGTTTCCTTAAATTTAGCATTGCATTTCAGTACTGACTGTGTAAGCTAAATTGCTGATCCAAAATAAAAACCCAGACT AGAATAGGGTTCTTAAAATCAAGTATCAATACAAAATAGAACACAATTAAAATCTTAATTGTTGGCTGGGCACAGTGGCTCACGCCTGTA ATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCATGAGGTTAGGAGAGCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTTTAC TAAAAATACAAAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACC CAGGAGGCGGAGCTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAGAGCTAGACTCTGTGTCAAAAATAAATGACT AGATAAAAAAAAAAATTGTTTGAGTACATTTTCCCTGCATTTTAGAGATTAGGACAGTGGTCACTTTCTAGTTGCCGTCTTCACAGACAA ACTTGAAAGGTATTAAGGAAAAAATTCCACATAGCTCTGGGCCTTTTTTGTATTCTGATTGCCACGTTAATCTGTAATCGTTAAGTACCC ATGAAAGAATGTGTTTCAGTATCAGTGCTTTTTTGGTACTTTAACAAGTATTGTAGGCACGGTGGATTTTTTTGAAATACCCATGTGTCC AATAGCAAGTTAAGGAACCTAGCGCATCAAATTTTGTTTTCTTCATTCATTTGGAACCTTATTTTCGCAAAAAACCTAGCTGGAATAATA ATGCCATATTGTATTTTGCACACTGCTTTATTTTCTAGAGGCTCTGGGAGCAAATTACATTCATCACATTACCTCTGCTCTCTCAAGATT AAAGTCTTTCAGCAACATTCTTTATTGTCATCATAAGGAAAAACTTTTATCGCAATGATAGTCAGTTCACATTAGTTTAGCACTATAGAT AGTATTCAGAAATTGCTTTCTCTTTGGTAAAGAAGATAAATAGGTGAATTTTATTGCCTGTGTTTTCAGGCTTCAGAGGTACCTGGCACC TTACTCAAGCAAAAACAAAAAACAGCTTTACTTCAAAAGCATGTGCCTCTGGTAAATTATCCATCACTTTTGTTTTAAAGTGGTCCCTCC AAGAATAATGTGGCATACACAGTGGGTTTGGTTGTAAGGCAGATGTAATAGATGACTTCAAAAGCCTGCTCCTTACTGCACTCTGGACAA GGCCCTGGTCTGTATAGTTTGGCTTCCTCTGTTAAGTCATTCTACAAGGTGACTTGCCATTTGAACTTTCGTAAGAGACCTCAGCAGTTA GACTGAGAAAAGTTAGAGTGCTGTAGTTATGAAGTCATACATTTTTGATAAAATACCTGTGGAAAACCAGGGATCCTCTCCTGTTTCTCT CTCTTGCCTCCCCCTTTCCCTCCATTCCTCTGTCGCCTCCCCCTCTCCTCCACTTTCTTTAAGAATCAGGGGGTACAGAATAACCTACAA ACAACCTCTTCAAAGTACCCTTGGAAATTGAAGTTCAATCTTAAGTTTTTTGCTGTCTTTAATTTACTAGAATTGCCTAATTTTTAGTTG ATTTCTCTACAGAGCTTAGCTTGTGTAGTTATTTCTCTTTTACTGTTGCTTTGGTGTGTCTTGAAGTTTGATTGATTATTTTTGGTCATT GAGTTCTTAGTGTAGTTTGCTAGATGATTATTAAGATTCTTTTGTGTCTGACACTTGTGGTGAGTTGCTTTTGAAATCTGTTGAGATTTC CATGTGAGAACTGATAATCAGGCTCTTGATCTGCTTCCCTAAATTACTTTTTTAGAGCCCAAACCCCAGGTTTAGGGTGAGGGTTTGTAA TACAAAGAAACACTTCCATCACTTCTGCCCTTAACCCTTGCCTCTATTACCTAAGCTTAGTAAGTAGTTTTCTTAATATTGTCCAATGTT TGGTGTTATCTGCATTGTTTTTTGTTTTTTTAATTGTGGTTGTTCTGACGTGTGAAATTTAAGGAAAGAGCCATTTTTTAAAAATGCCGA GCAGGGCAATGCAAGTACAGCCAAATATTAGACTTGATGTGCAATCTTCGGTCCTTTTTAATCTGGGGTATTATAGGCAGTACTTTAAAT TGCAAAGTCTTCCGGGCCTATTTTCCTCTACATTTTTGTAATTAACTCTGGGGGCTTACTTGTTTTGGCAGTACTGAAATCAAAGGAGCT GGTTCTTCTTTTCTCCCAATTATTTTCATATGAAAGCACCTACAATTAGCCTGTTAGTCCTATTCAGATACATCAAATATCAGTGAATGC TTTACTATTCGCACATTTAAGCATCTTTGTTTTACATAAAATTAGAGTATGAAAACCAGTGTTCAATTTTTTATCTTGTTGAGCTTGTAA AATGCCAGCAATTTAAAACTAGGACTTTTCCCCCCATAAGCCAAGGAGGTAGAATTACTAATACAAGGGTTAAAGAAGGTAGATTTTGTT TTCAATATTTGGGTAATATTAGAAAGATTCTTCCCACAGGGAAGAACTAGCAAGTGTCCCAATTTTTTCCAAACGTTGGGGAGGGGAAAA TTCACTGTATCATGAAACCCTAAGGGTTTGTTGCACTTCCTGCTTTTTAGGCCTGGATAACAGTATCACCATCCTTATTTACAGAAGGGT AAAACTGACTCTTAATGAGAAAAGCTTTATAAGTTCAAGGGCTGTAAAATATGAACTACTTAGGGTCGTTTGCCTTCCATGGGAACTTGG CTAGACTTAGAAAAAGCTGTTTGTTGTGCTAATGTAAAAGTGTCATACAATTTAGAAGATTTTTGAAGATGGTAAACTTAGAAGAATTCT ATGTTCTGAAATGCACACTTTTAGAATGTTTTTCTTTGAAAACAGGCTAATAGTTTTTTCTTTTTTTGACAAAGTTTCAGCTCCTCTTTA AAGTTATTGTGTCATTTTTCTGGTTTAAATTTCCCTTATATTTCCACCTGTAATGTCAGTGGCAACAACATCATACTTCACTTACTTGTT AATTTACTTTTTACCCTTATTCTAAGAGCAAGTTGAGTTGAACTGAATCTTCCTTGTCTTAGTAACAATGTATAAATAGTGGCTTTTCTG TACAAAAGGTTGTAATGCCTCCTGATGGATATAATTTTGTGATTGTATTTAAAAGTTGAATAAATCACACCAGCTTCCTGAAAATGTTCA TAATGCATCTTTTGGAAAACAAATACATGCCTACTTTGTGCATATTTGCATTAACATGGCAAAGATTGTATGAAATACCTGTTTTTCAGA >95597_95597_4_TXNL4B-SMG1_TXNL4B_chr16_72122885_ENST00000426362_SMG1_chr16_18891041_ENST00000389467_length(amino acids)=3230AA_BP=1 MYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPSMTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEK LFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPVLETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVI FDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTA TKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPD DLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNW LERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEG HGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTS LSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANA GRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKF VECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAI GPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKEQTVPIRSHLM ELGLTAAKFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQSTHAMEMLSSCAISFC KSVKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLSTLSKNILTLIELPSVNTMEEEYPRIESESTVHIGVGEPDFILG QLYHLSSVQAPEVAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQAVCRPAGIQDEDITLQI TESEDNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQIPLDEDDPRLHLSHRVEQSTD DMIVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLILYPAIVGTISLSSESQ ASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLW DELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWFQDNYGDAIENAL EKLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKPKKLLF LGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQK AQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTA VMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLT LLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVLPKLDGSLDEYLSLQEQL TDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRYSEHTQLQTQQRAVQEAIQVKLNEFEQWITHYQAAFNNLEATQLASLLQEISTQMDL GPPSYVPATAFLQNAGQAHLISQCEQLEGEVGALLQQRRSVLRGCLEQLHHYATVALQYPKAIFQKHRIEQWKTWMEELICNTTVERCQE LYRKYEMQYAPQPPPTVCQFITATEMTLQRYAADINSRLIRQVERLKQEAVTVPVCEDQLKEIERCIKVFLHENGEEGSLSLASVIISAL CTLTRRNLMMEGAASSAGEQLVDLTSRDGAWFLEELCSMSGNVTCLVQLLKQCHLVPQDLDIPNPMEASETVHLANGVYTSLQELNSNFR QIIFPEALRCLMKGEYTLESMLHELDGLIEQTTDGVPLQTLVESLQAYLRNAAMGLEEETHAHYIDVARLLHAQYGELIQPRNGSVDETP KMSAGQMLLVAFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREARSTQVNFFDDDNHRQVLEEIFFLKRLQTIKEFFRLCGTFSKT LSGSSSLEDQNTVNGPVQIVNVKTLFRNSCFSEDQMAKPIKAFTADFVRQLLIGLPNQALGLTLCSFISALGVDIIAQVEAKDFGAESKV SVDDLCKKAVEHNIQIGKFSQLVMNRATVLASSYDTAWKKHDLVRRLETSISSCKTSLQRVQLHIAMFQQWQHEDLLINRPQAMSVTPPP RSAILTSMKKKLHTLSQIETSIATVQEKLAALESSIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQRASQVTFLCSNIIHFES LRTRTAEALNLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDTGLEHPIGSSEWLLSAHKQLTQDMSTQRAIQTEKEQQIETVC ETIQNLVDNIKTVLTGHNRQLGDVKHLLKAMAKDEEAALADGEDVPYENSVRQFLGEYKSWQDNIQTVLFTLVQAMGQVRSQEHVEMLQE ITPTLKELKTQSQSIYNNLVSFASPLVTDATNECSSPTSSATYQPSFAAAVRSNTGQKTQPDVMSQNARKLIQKNLATSADTPPSTVPGT -------------------------------------------------------------- >95597_95597_5_TXNL4B-SMG1_TXNL4B_chr16_72122885_ENST00000426362_SMG1_chr16_18891041_ENST00000446231_length(transcript)=14968nt_BP=559nt GAGATCGCCCACCAGATTGCCTGGTATAAATGACACTGTGAGAGAGCAGAGGAAGACACAAGGAGTCCTACTCGGGCTCGGTGACAGTCT GGGGTGGGTTAAAGCGGAGGCCTGGGAGAGGGACCAAGGCCACTCCAGGCAGCATCCCTGGATCTCAGCGAGGCCGCTCCAGGCAGCAGG ATTTGACCAGAGCAAGGAGGAAGGCCAAGGCGGCCAGGACGGATGCAGCATCCCTGAGGAGTGACAGTGAGGATTCACATTTGGGTTATT TCAAGATGAGCTTCCTACTGCCCAAGCTGACTAGCAAAAAGGAAGTAGACCAGGCGATAAAAAGTACTGCTGAGAAGGTGTTGGTTCTCA GGTTTGGGAGAGATGAAGATCCTGTCTGTCTGCAGCTAGATGATATTCTTTCTAAGACCTCTTCTGACTTAAGTAAAATGGCTGCTATAT ACCTGGTAGATGTGGACCAAACTGCAGTTTATACACAGTATTTTGACATCAGTTATATTCCATCTACTGTCTTTTTCTTCAATGGGCAGC ATATGAAAGTGGATTATGGGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAGGCTGTGTTGACAGC TGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACATATGGATTAGACCA ACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAGATAAATACGAAACT GCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAGGTTGTTGCTGTAGC CCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGAGAAATGACTTGTGC CCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCATGTGTTCAATGTAGA CAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGGATGTGGGCGCTATC TCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCT CTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGT GATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCA GGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCC GTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGC TCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACA AGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATT AAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCA TAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCT CCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAG AGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGAC AACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTA TAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGA CTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCT TACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTG TCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGA AGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATC GGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACC GACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGA ATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAG CAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAA AGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAG AAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAA GCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTA TTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATG TAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGAACAAACAGT CCCAATTAGAAGCCATCTCATGGAATTAGGTCTAACAGCAGCAAAATTTGCTAGAAAACGAGGGAATGTGTCCCTTGCAACAAGACTGCT GGCACAGTGCAGTGAAGTTCAGCTGGGAAAGACCACCACTGCACAGGATTTAGTCCAACATTTTAAAAAACTATCAACCCAAGGTCAAGT GGATGAAAAATGGGGGCCCGAACTTGATATTGAAAAAACCAAATTGCTTTATACAGCAGGCCAGTCAACACATGCAATGGAAATGTTGAG TTCTTGTGCCATATCTTTCTGCAAGTCTGTGAAAGCTGAATATGCAGTTGCTAAATCAATTCTGACACTGGCTAAATGGATCCAGGCAGA ATGGAAAGAGATTTCAGGACAGCTGAAACAGGTTTACAGAGCTCAGCACCAACAGAACTTCACAGGTCTTTCTACTTTGTCTAAAAACAT ACTCACTCTAATAGAACTGCCATCTGTTAATACGATGGAAGAAGAGTATCCTCGGATCGAGAGTGAATCTACAGTGCATATTGGAGTTGG AGAACCTGACTTCATTTTGGGACAGTTGTATCACCTGTCTTCAGTACAGGCACCTGAAGTAGCCAAATCTTGGGCAGCGTTGGCCAGCTG GGCTTATAGGTGGGGCAGAAAGGTGGTTGACAATGCCAGTCAGGGAGAAGGTGTTCGTCTGCTGCCTAGAGAAAAATCTGAAGTTCAGAA TCTACTTCCAGACACTATAACTGAGGAAGAGAAAGAGAGAATATATGGTATTCTTGGACAGGCTGTGTGTCGGCCGGCGGGGATTCAGGA TGAAGATATAACACTTCAGATAACTGAGAGTGAAGACAACGAAGAAGATGACATGGTTGATGTTATCTGGCGTCAGTTGATATCAAGCTG CCCATGGCTTTCAGAACTTGATGAAAGTGCAACTGAAGGAGTTATTAAAGTGTGGAGGAAAGTTGTAGATAGAATATTCAGCCTGTACAA ACTCTCTTGCAGTGCATACTTTACTTTCCTTAAACTCAACGCTGGTCAAATTCCTTTAGATGAGGATGACCCTAGGCTGCATTTAAGTCA CAGAGTGGAACAGAGCACTGATGACATGATTGTGATGGCCACATTGCGCCTGCTGCGGTTGCTCGTGAAGCATGCTGGTGAGCTTCGGCA GTATCTGGAGCACGGCTTGGAGACAACACCCACTGCACCATGGAGAGGAATTATTCCGCAACTTTTCTCACGCTTAAACCACCCTGAAGT GTATGTGCGCCAAAGTATTTGTAACCTTCTCTGCCGTGTGGCTCAAGATTCCCCACATCTCATATTGTATCCTGCAATAGTGGGTACCAT ATCGCTTAGTAGTGAATCCCAGGCTTCAGGAAATAAATTTTCCACTGCAATTCCAACTTTACTTGGCAATATTCAAGGAGAAGAATTGCT GGTTTCTGAATGTGAGGGAGGAAGTCCTCCTGCATCTCAGGATAGCAATAAGGATGAACCTAAAAGTGGATTAAATGAAGACCAAGCCAT GATGCAGGATTGTTACAGCAAAATTGTAGATAAGCTGTCCTCTGCAAACCCCACCATGGTATTACAGGTTCAGATGCTCGTGGCTGAACT GCGCAGGGTCACTGTGCTCTGGGATGAGCTCTGGCTGGGAGTTTTGCTGCAACAACACATGTATGTCCTGAGACGAATTCAGCAGCTTGA AGATGAGGTGAAGAGAGTCCAGAACAACAACACCTTACGCAAAGAAGAGAAAATTGCAATCATGAGGGAGAAGCACACAGCTTTGATGAA GCCCATCGTATTTGCTTTGGAGCATGTGAGGAGTATCACAGCGGCTCCTGCAGAAACACCTCATGAAAAATGGTTTCAGGATAACTATGG TGATGCCATTGAAAATGCCCTAGAAAAACTGAAGACTCCATTGAACCCTGCAAAGCCTGGGAGCAGCTGGATTCCATTTAAAGAGATAAT GCTAAGTTTGCAACAGAGAGCACAGAAACGTGCAAGTTACATCTTGCGTCTTGAAGAAATCAGTCCATGGTTGGCTGCCATGACTAACAC TGAAATTGCTCTTCCTGGGGAAGTCTCAGCCAGAGACACTGTCACAATCCATAGTGTGGGCGGAACCATCACAATCTTACCGACTAAAAC CAAGCCAAAGAAACTTCTCTTTCTTGGATCAGATGGGAAGAGCTATCCTTATCTTTTCAAAGGACTGGAGGATTTACATCTGGATGAGAG AATAATGCAGTTCCTATCTATTGTGAATACCATGTTTGCTACAATTAATCGCCAAGAAACACCCCGGTTCCATGCTCGACACTATTCTGT AACACCACTAGGAACAAGATCAGGACTAATCCAGTGGGTAGATGGAGCCACACCCTTATTTGGTCTTTACAAACGATGGCAACAACGGGA AGCTGCCTTACAAGCACAAAAGGCCCAAGATTCCTACCAAACTCCTCAGAATCCTGGAATTGTACCCCGTCCTAGTGAACTTTATTACAG TAAAATTGGCCCTGCTTTGAAAACAGTTGGGCTTAGCCTGGATGTGTCCCGTCGGGATTGGCCTCTTCATGTAATGAAGGCAGTATTGGA AGAGTTAATGGAGGCCACACCCCCGAATCTCCTTGCCAAAGAGCTCTGGTCATCTTGCACAACACCTGATGAATGGTGGAGAGTTACGCA GTCTTATGCAAGATCTACTGCAGTCATGTCTATGGTTGGATACATAATTGGCCTTGGAGACAGACATCTGGATAATGTTCTTATAGATAT GACGACTGGAGAAGTTGTTCACATAGATTACAATGTTTGCTTTGAAAAAGGTAAAAGCCTTAGAGTTCCTGAGAAAGTACCTTTTCGAAT GACACAAAACATTGAAACAGCACTGGGTGTAACTGGAGTAGAAGGTGTATTTAGGCTTTCATGTGAGCAGGTTTTACACATTATGCGGCG TGGCAGAGAGACCCTGCTGACGCTGCTGGAGGCCTTTGTGTACGACCCTCTGGTGGACTGGACAGCAGGAGGCGAGGCTGGGTTTGCTGG TGCTGTCTATGGTGGAGGTGGCCAGCAGGCCGAGAGCAAGCAGAGCAAGAGAGAGATGGAGCGAGAGATCACCCGCAGCCTGTTTTCTTC TAGAGTAGCTGAGATTAAGGTGAACTGGTTTAAGAATAGAGATGAGATGCTGGTTGTGCTTCCCAAGTTGGACGGTAGCTTAGATGAATA CCTAAGCTTGCAAGAGCAACTGACAGATGTGGAAAAACTGCAGGGCAAACTACTGGAGGAAATAGAGTTTCTAGAAGGAGCTGAAGGGGT GGATCATCCTTCTCATACTCTGCAACACAGGTATTCTGAGCACACCCAACTACAGACTCAGCAAAGAGCTGTTCAGGAAGCAATCCAGGT GAAGCTGAATGAATTTGAACAATGGATAACACATTATCAGGCTGCATTCAATAATTTAGAAGCAACACAGCTTGCAAGCTTGCTTCAAGA GATAAGCACACAAATGGACCTTGGTCCTCCAAGTTACGTGCCAGCAACAGCCTTTCTGCAGAATGCTGGTCAGGCCCACTTGATTAGCCA GTGCGAGCAGCTGGAGGGGGAGGTTGGTGCTCTCCTGCAGCAGAGGCGCTCCGTGCTCCGTGGCTGTCTGGAGCAACTGCATCACTATGC AACCGTGGCCCTGCAGTATCCGAAGGCCATATTTCAGAAACATCGAATTGAACAGTGGAAGACCTGGATGGAAGAGCTCATCTGTAACAC CACAGTAGAGCGTTGTCAAGAGCTCTATAGGAAATATGAAATGCAATATGCTCCCCAGCCACCCCCAACAGTGTGTCAGTTCATCACTGC CACTGAAATGACCCTGCAGCGATACGCAGCAGACATCAACAGCAGACTTATTAGACAAGTGGAACGCTTGAAACAGGAAGCTGTCACTGT GCCAGTTTGTGAAGATCAGTTGAAAGAAATTGAACGTTGCATTAAAGTTTTCCTTCATGAGAATGGAGAAGAAGGATCTTTGAGTCTAGC AAGTGTTATTATTTCTGCCCTTTGTACCCTTACAAGGCGTAACCTGATGATGGAAGGTGCAGCGTCAAGTGCTGGAGAACAGCTGGTTGA TCTGACTTCTCGGGATGGAGCCTGGTTCTTGGAGGAACTCTGCAGTATGAGCGGAAACGTCACCTGCTTGGTTCAGTTACTGAAGCAGTG CCACCTGGTGCCACAGGACTTAGATATCCCGAACCCCATGGAAGCGTCTGAGACAGTTCACTTAGCCAATGGAGTGTATACCTCACTTCA GGAATTGAATTCGAATTTCCGGCAAATCATATTTCCAGAAGCACTTCGATGTTTAATGAAAGGGGAATACACGTTAGAAAGTATGCTGCA TGAACTGGACGGTCTTATTGAGCAGACCACCGATGGCGTTCCCCTGCAGACTCTAGTGGAATCTCTTCAGGCCTACTTAAGAAACGCAGC TATGGGACTGGAAGAAGAAACACATGCTCATTACATCGATGTTGCCAGACTACTACATGCTCAGTACGGTGAATTAATCCAACCGAGAAA TGGTTCAGTTGATGAAACACCCAAAATGTCAGCTGGCCAGATGCTTTTGGTAGCATTCGATGGCATGTTTGCTCAAGTTGAAACTGCTTT CAGCTTATTAGTTGAAAAGTTGAACAAGATGGAAATTCCCATAGCTTGGCGAAAGATTGACATCATAAGGGAAGCCAGGAGTACTCAAGT TAATTTTTTTGATGATGATAATCACCGGCAGGTGCTAGAAGAGATTTTCTTTCTAAAAAGACTACAGACTATTAAGGAGTTCTTCAGGCT CTGTGGTACCTTTTCTAAAACATTGTCAGGATCAAGTTCACTTGAAGATCAGAATACTGTGAATGGGCCTGTACAGATTGTCAATGTGAA AACCCTTTTTAGAAACTCTTGTTTCAGTGAAGACCAAATGGCCAAACCTATCAAGGCATTCACAGCTGACTTTGTGAGGCAGCTCTTGAT AGGGCTACCCAACCAAGCCCTCGGACTCACACTGTGCAGTTTTATCAGTGCTCTGGGTGTAGACATCATTGCTCAAGTAGAGGCAAAGGA CTTTGGTGCCGAAAGCAAAGTTTCTGTTGATGATCTCTGTAAGAAAGCGGTGGAACATAACATCCAGATAGGGAAGTTCTCTCAGCTGGT TATGAACAGGGCAACTGTGTTAGCAAGTTCTTACGACACTGCCTGGAAGAAGCATGACTTGGTGCGAAGGCTAGAAACCAGTATTTCTTC TTGTAAGACAAGCCTGCAGCGGGTTCAGCTGCATATTGCCATGTTTCAGTGGCAACATGAAGATCTACTTATCAATAGACCACAAGCCAT GTCAGTCACACCTCCCCCACGGTCTGCTATCCTAACCAGCATGAAAAAGAAGCTGCATACCCTGAGCCAGATTGAAACTTCTATTGCAAC AGTTCAGGAGAAGCTAGCTGCACTTGAATCAAGTATTGAACAGCGACTCAAGTGGGCAGGTGGTGCCAACCCTGCATTGGCCCCTGTACT ACAAGATTTTGAAGCAACGATAGCTGAAAGAAGAAATCTTGTCCTTAAAGAGAGCCAAAGAGCAAGTCAGGTCACATTTCTCTGCAGCAA TATCATTCATTTTGAAAGTTTACGAACAAGAACTGCAGAAGCCTTAAACCTGGATGCGGCGTTATTTGAACTAATCAAGCGATGTCAGCA GATGTGTTCGTTTGCATCACAGTTTAACAGTTCAGTGTCTGAGTTAGAGCTTCGTTTATTACAGAGAGTGGACACTGGTCTTGAACATCC TATTGGCAGCTCTGAATGGCTTTTGTCAGCACACAAACAGTTGACCCAGGATATGTCTACTCAGAGGGCAATTCAGACAGAGAAAGAGCA GCAGATAGAAACGGTCTGTGAAACAATTCAGAATCTGGTTGATAATATAAAGACTGTGCTCACTGGTCATAACCGACAGCTTGGAGATGT CAAACATCTCTTGAAAGCTATGGCTAAGGATGAAGAAGCTGCTCTGGCAGATGGTGAAGATGTTCCCTATGAGAACAGTGTTAGGCAGTT TTTGGGTGAATATAAATCATGGCAAGACAACATTCAAACAGTTCTATTTACATTAGTCCAGGCTATGGGTCAGGTTCGAAGTCAAGAACA CGTTGAAATGCTCCAGGAAATCACTCCCACCTTGAAAGAACTGAAAACACAAAGTCAGAGTATCTATAATAATTTAGTGAGTTTTGCATC ACCCTTAGTCACCGATGCAACAAATGAATGTTCGAGTCCAACGTCATCTGCTACTTATCAGCCATCCTTCGCTGCAGCAGTCCGGAGTAA CACTGGCCAGAAGACTCAGCCTGATGTCATGTCACAGAATGCTAGAAAGCTGATCCAAAAAAATCTTGCTACATCAGCTGATACTCCACC AAGCACCGTTCCAGGAACTGGCAAGAGTGTTGCTTGTAGTCCTAAAAAGGCAGTCAGAGACCCTAAAACTGGGAAAGCGGTGCAAGAGAG AAACTCCTATGCAGTGAGTGTGTGGAAGAGAGTGAAAGCCAAGTTAGAGGGCCGAGATGTTGATCCGAATAGGAGGATGTCAGTTGCTGA ACAGGTTGACTATGTCATTAAGGAAGCAACTAATCTAGATAACTTGGCTCAGCTGTATGAAGGTTGGACAGCCTGGGTGTGAATGGCAAG ACAGTAGATGAGTCTGGTTAAGCGAGGTCAGACATCCACCAGAATCAACTCAGCCTCAGGCATCCAAAGCCACACCACAGTCGGTGGTGA TGCAACTGGGGGCTTACTCTGAGGAAACCTAGGAAATCTCGGTGCACTAGGAAGTGAATCCCGCAGGACAGCTGCACTCAGGGATACGCC CAACACCATGGCCTGCAACCCCAGGGTCAAGGGTGAAGGAAAGCAAGCTCACCGCCTGAACACGGAGATTGTCTTTCTGCCACAGAACAG CAGCAGACGTGTCGGGAGGTTAGCTGCGGAAAGAAATCGGGATGCCGCGGAGCACAGAGTGATTTGGAACTCCATTCCACCTGACCCTGT GTGTACAATCCAGGAAAAAAACAAACCCCACTCAGAAACAGAGAAAACTGGGGTCGCGAAGAAATCACAGCCAAGGAAGATTTGATGCAT TCAGATTCTCGTGTAACACTTGTTGCTTGGCAACAGTACTGGTTGGGTTGACCAGTAAGTAGAAAAAGGCTAAAGGCTATGCGATATGAA TTTCAGAAATGGACTGAAAATGGAGAGCTATGTAACAGATACACTACAGTAGAAGAACTTACTTCTGAAATGAAGGGAAAAAAACCACCC CATCGTTCCCTACTCCTCCCCACCACTTACCCGTTCCCCCTTTACCTAATCTAGTAGATTAGCCATCTTTCAAATTCACTTTTATTTCAG TCCTTATATTTCATATACTTCCGTCTCGATGCTGTTAACAACTTCTGATAACATGGAAAATTCAAGGATTGTTTAAAGGTCTGATGATCA CACACAAAATGTAATTCCGGTTATTTAAGTCATTTCTGTGATTCTATCATGTACAGTTTCCAGAATTGTCACTGTGCATTCAAAAGTAAT GAATCTAACAGACATTTGATTTAATGTACACTCCCTTTTGCTTATAGTGTGCATTTTTTTTGGAGGTCATTCAAATTTTCCCTCTTCTGT GATAGCTGTAGTTTCTTTCATAGAAAGTAGCTAATCCAGTGTAATCTTTTACCTTTTTAAAAACCAAGATAGAGTATCTATTAGAGTTTT ACATTGTTGATGATAGATTAACAATAAAGTGATGTTCTGGTGGAGGTAGACTGAAATTTTTTTAATTCATGTTTTTCATTTGATACTTTT AATTTACACTTAGTAAATTAAAAGTTGTTTAATTTACTTGGCATTTTAGGACATGTACATGAAACAGTGAAAATGAGATCCACCAACATC TTTTATTAAGTTCAGTTATTAGTCTGTGAAGTGCTTTACTTTTTGCACAATTTTAATAGCTTGCTATTCAGTAATACATTATAGTGAATT CATGATCAAGGTTTCCTTAAATTTAGCATTGCATTTCAGTACTGACTGTGTAAGCTAAATTGCTGATCCAAAATAAAAACCCAGACTAGA ATAGGGTTCTTAAAATCAAGTATCAATACAAAATAGAACACAATTAAAATCTTAATTGTTGGCTGGGCACAGTGGCTCACGCCTGTAATC CCAGCACTTTGGGAGGCCGAGGCGGGCGGATCATGAGGTTAGGAGAGCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTTTACTAA AAATACAAAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAG GAGGCGGAGCTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAGAGCTAGACTCTGTGTCAAAAATAAATGACTAGA TAAAAAAAAAAATTGTTTGAGTACATTTTCCCTGCATTTTAGAGATTAGGACAGTGGTCACTTTCTAGTTGCCGTCTTCACAGACAAACT TGAAAGGTATTAAGGAAAAAATTCCACATAGCTCTGGGCCTTTTTTGTATTCTGATTGCCACGTTAATCTGTAATCGTTAAGTACCCATG AAAGAATGTGTTTCAGTATCAGTGCTTTTTTGGTACTTTAACAAGTATTGTAGGCACGGTGGATTTTTTTGAAATACCCATGTGTCCAAT AGCAAGTTAAGGAACCTAGCGCATCAAATTTTGTTTTCTTCATTCATTTGGAACCTTATTTTCGCAAAAAACCTAGCTGGAATAATAATG CCATATTGTATTTTGCACACTGCTTTATTTTCTAGAGGCTCTGGGAGCAAATTACATTCATCACATTACCTCTGCTCTCTCAAGATTAAA GTCTTTCAGCAACATTCTTTATTGTCATCATAAGGAAAAACTTTTATCGCAATGATAGTCAGTTCACATTAGTTTAGCACTATAGATAGT ATTCAGAAATTGCTTTCTCTTTGGTAAAGAAGATAAATAGGTGAATTTTATTGCCTGTGTTTTCAGGCTTCAGAGGTACCTGGCACCTTA CTCAAGCAAAAACAAAAAACAGCTTTACTTCAAAAGCATGTGCCTCTGGTAAATTATCCATCACTTTTGTTTTAAAGTGGTCCCTCCAAG AATAATGTGGCATACACAGTGGGTTTGGTTGTAAGGCAGATGTAATAGATGACTTCAAAAGCCTGCTCCTTACTGCACTCTGGACAAGGC CCTGGTCTGTATAGTTTGGCTTCCTCTGTTAAGTCATTCTACAAGGTGACTTGCCATTTGAACTTTCGTAAGAGACCTCAGCAGTTAGAC TGAGAAAAGTTAGAGTGCTGTAGTTATGAAGTCATACATTTTTGATAAAATACCTGTGGAAAACCAGGGATCCTCTCCTGTTTCTCTCTC TTGCCTCCCCCTTTCCCTCCATTCCTCTGTCGCCTCCCCCTCTCCTCCACTTTCTTTAAGAATCAGGGGGTACAGAATAACCTACAAACA ACCTCTTCAAAGTACCCTTGGAAATTGAAGTTCAATCTTAAGTTTTTTGCTGTCTTTAATTTACTAGAATTGCCTAATTTTTAGTTGATT TCTCTACAGAGCTTAGCTTGTGTAGTTATTTCTCTTTTACTGTTGCTTTGGTGTGTCTTGAAGTTTGATTGATTATTTTTGGTCATTGAG TTCTTAGTGTAGTTTGCTAGATGATTATTAAGATTCTTTTGTGTCTGACACTTGTGGTGAGTTGCTTTTGAAATCTGTTGAGATTTCCAT GTGAGAACTGATAATCAGGCTCTTGATCTGCTTCCCTAAATTACTTTTTTAGAGCCCAAACCCCAGGTTTAGGGTGAGGGTTTGTAATAC AAAGAAACACTTCCATCACTTCTGCCCTTAACCCTTGCCTCTATTACCTAAGCTTAGTAAGTAGTTTTCTTAATATTGTCCAATGTTTGG TGTTATCTGCATTGTTTTTTGTTTTTTTAATTGTGGTTGTTCTGACGTGTGAAATTTAAGGAAAGAGCCATTTTTTAAAAATGCCGAGCA GGGCAATGCAAGTACAGCCAAATATTAGACTTGATGTGCAATCTTCGGTCCTTTTTAATCTGGGGTATTATAGGCAGTACTTTAAATTGC AAAGTCTTCCGGGCCTATTTTCCTCTACATTTTTGTAATTAACTCTGGGGGCTTACTTGTTTTGGCAGTACTGAAATCAAAGGAGCTGGT TCTTCTTTTCTCCCAATTATTTTCATATGAAAGCACCTACAATTAGCCTGTTAGTCCTATTCAGATACATCAAATATCAGTGAATGCTTT ACTATTCGCACATTTAAGCATCTTTGTTTTACATAAAATTAGAGTATGAAAACCAGTGTTCAATTTTTTATCTTGTTGAGCTTGTAAAAT GCCAGCAATTTAAAACTAGGACTTTTCCCCCCATAAGCCAAGGAGGTAGAATTACTAATACAAGGGTTAAAGAAGGTAGATTTTGTTTTC AATATTTGGGTAATATTAGAAAGATTCTTCCCACAGGGAAGAACTAGCAAGTGTCCCAATTTTTTCCAAACGTTGGGGAGGGGAAAATTC ACTGTATCATGAAACCCTAAGGGTTTGTTGCACTTCCTGCTTTTTAGGCCTGGATAACAGTATCACCATCCTTATTTACAGAAGGGTAAA ACTGACTCTTAATGAGAAAAGCTTTATAAGTTCAAGGGCTGTAAAATATGAACTACTTAGGGTCGTTTGCCTTCCATGGGAACTTGGCTA GACTTAGAAAAAGCTGTTTGTTGTGCTAATGTAAAAGTGTCATACAATTTAGAAGATTTTTGAAGATGGTAAACTTAGAAGAATTCTATG TTCTGAAATGCACACTTTTAGAATGTTTTTCTTTGAAAACAGGCTAATAGTTTTTTCTTTTTTTGACAAAGTTTCAGCTCCTCTTTAAAG TTATTGTGTCATTTTTCTGGTTTAAATTTCCCTTATATTTCCACCTGTAATGTCAGTGGCAACAACATCATACTTCACTTACTTGTTAAT TTACTTTTTACCCTTATTCTAAGAGCAAGTTGAGTTGAACTGAATCTTCCTTGTCTTAGTAACAATGTATAAATAGTGGCTTTTCTGTAC AAAAGGTTGTAATGCCTCCTGATGGATATAATTTTGTGATTGTATTTAAAAGTTGAATAAATCACACCAGCTTCCTGAAAATGTTCATAA TGCATCTTTTGGAAAACAAATACATGCCTACTTTGTGCATATTTGCATTAACATGGCAAAGATTGTATGAAATACCTGTTTTTCAGAAAA >95597_95597_5_TXNL4B-SMG1_TXNL4B_chr16_72122885_ENST00000426362_SMG1_chr16_18891041_ENST00000446231_length(amino acids)=3229AA_BP=1 MYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPSMTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEK LFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPVLETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVI FDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTA TKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPD DLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNW LERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEG HGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTS LSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANA GRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKF VECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAI GPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKEQTVPIRSHLM ELGLTAAKFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQSTHAMEMLSSCAISFC KSVKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLSTLSKNILTLIELPSVNTMEEEYPRIESESTVHIGVGEPDFILG QLYHLSSVQAPEVAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQAVCRPAGIQDEDITLQI TESEDNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQIPLDEDDPRLHLSHRVEQSTD DMIVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLILYPAIVGTISLSSESQ ASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLW DELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWFQDNYGDAIENAL EKLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKPKKLLF LGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQK AQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTA VMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLT LLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVLPKLDGSLDEYLSLQEQL TDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRYSEHTQLQTQQRAVQEAIQVKLNEFEQWITHYQAAFNNLEATQLASLLQEISTQMDL GPPSYVPATAFLQNAGQAHLISQCEQLEGEVGALLQQRRSVLRGCLEQLHHYATVALQYPKAIFQKHRIEQWKTWMEELICNTTVERCQE LYRKYEMQYAPQPPPTVCQFITATEMTLQRYAADINSRLIRQVERLKQEAVTVPVCEDQLKEIERCIKVFLHENGEEGSLSLASVIISAL CTLTRRNLMMEGAASSAGEQLVDLTSRDGAWFLEELCSMSGNVTCLVQLLKQCHLVPQDLDIPNPMEASETVHLANGVYTSLQELNSNFR QIIFPEALRCLMKGEYTLESMLHELDGLIEQTTDGVPLQTLVESLQAYLRNAAMGLEEETHAHYIDVARLLHAQYGELIQPRNGSVDETP KMSAGQMLLVAFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREARSTQVNFFDDDNHRQVLEEIFFLKRLQTIKEFFRLCGTFSKT LSGSSSLEDQNTVNGPVQIVNVKTLFRNSCFSEDQMAKPIKAFTADFVRQLLIGLPNQALGLTLCSFISALGVDIIAQVEAKDFGAESKV SVDDLCKKAVEHNIQIGKFSQLVMNRATVLASSYDTAWKKHDLVRRLETSISSCKTSLQRVQLHIAMFQWQHEDLLINRPQAMSVTPPPR SAILTSMKKKLHTLSQIETSIATVQEKLAALESSIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQRASQVTFLCSNIIHFESL RTRTAEALNLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDTGLEHPIGSSEWLLSAHKQLTQDMSTQRAIQTEKEQQIETVCE TIQNLVDNIKTVLTGHNRQLGDVKHLLKAMAKDEEAALADGEDVPYENSVRQFLGEYKSWQDNIQTVLFTLVQAMGQVRSQEHVEMLQEI TPTLKELKTQSQSIYNNLVSFASPLVTDATNECSSPTSSATYQPSFAAAVRSNTGQKTQPDVMSQNARKLIQKNLATSADTPPSTVPGTG -------------------------------------------------------------- >95597_95597_6_TXNL4B-SMG1_TXNL4B_chr16_72122885_ENST00000426362_SMG1_chr16_18891041_ENST00000565224_length(transcript)=1672nt_BP=559nt GAGATCGCCCACCAGATTGCCTGGTATAAATGACACTGTGAGAGAGCAGAGGAAGACACAAGGAGTCCTACTCGGGCTCGGTGACAGTCT GGGGTGGGTTAAAGCGGAGGCCTGGGAGAGGGACCAAGGCCACTCCAGGCAGCATCCCTGGATCTCAGCGAGGCCGCTCCAGGCAGCAGG ATTTGACCAGAGCAAGGAGGAAGGCCAAGGCGGCCAGGACGGATGCAGCATCCCTGAGGAGTGACAGTGAGGATTCACATTTGGGTTATT TCAAGATGAGCTTCCTACTGCCCAAGCTGACTAGCAAAAAGGAAGTAGACCAGGCGATAAAAAGTACTGCTGAGAAGGTGTTGGTTCTCA GGTTTGGGAGAGATGAAGATCCTGTCTGTCTGCAGCTAGATGATATTCTTTCTAAGACCTCTTCTGACTTAAGTAAAATGGCTGCTATAT ACCTGGTAGATGTGGACCAAACTGCAGTTTATACACAGTATTTTGACATCAGTTATATTCCATCTACTGTCTTTTTCTTCAATGGGCAGC ATATGAAAGTGGATTATGGGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAGGCTGTGTTGACAGC TGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACATATGGATTAGACCA ACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAGATAAATACGAAACT GCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAGGTTGTTGCTGTAGC CCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGAGAAATGACTTGTGC CCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCATGTGTTCAATGTAGA CAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGGGTGAGTCTTTAATT GTAATGACTTTGTTTTATCCACAGTTAAGCCTTTTCTCATTACATATTTATGTATTTCACTGTCATGTCAAGATGTCTGCAGAATCACTG TGTGTAACAAACAGCCATATTTAAGACATGCCTGGATAAATAAAATTGGTAGGAATGTTTTCTTGGCATTATATTTAACTTTTCTTCTTC TTTTTCCTTGACAAATCTTGATAAGTTTTTTTATATTAGTTTTATTTTCTAGAAAATGTCTTATGAATTTCTCCTATTTGCTCTAGCATG CTTATAGAAAATGTCAGTGTTTCTTACAGCTCAAATTTGTGTAGTTGTTTTAAAATGCGGTCTCTTTCTTCTTCCCCTGGTACTTTTTTC TTTCTGTCTACTGAAGTTAGTTCTTATACATGGTCTTATATTTTGGCTGTCTCTTTTCCCTAGGAACATTCATACAGGTTGAATATTCCT >95597_95597_6_TXNL4B-SMG1_TXNL4B_chr16_72122885_ENST00000426362_SMG1_chr16_18891041_ENST00000565224_length(amino acids)=201AA_BP=1 MYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPSMTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEK LFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPVLETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVI -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for TXNL4B-SMG1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Tgene | SMG1 | chr16:72122885 | chr16:18891041 | ENST00000446231 | 9 | 63 | 1_1977 | 431.0 | 3662.0 | SMG8 and SMG9 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for TXNL4B-SMG1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for TXNL4B-SMG1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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